Deep learning for neuroimaging: a validation study
Authors: Sergey M. Plis, Devon R. Hjelm, Ruslan Salakhutdinov, Vince D. Calhoun
ICLR 2014

Abstract: Deep learning methods have recently enjoyed a number of successes in the tasks of classification and representation learning. These tasks are very important for brain imaging and neuroscience discovery, making the methods attractive candidates for porting to a neuroimager's toolbox. Successes are, in part, explained by a great flexibility of deep learning models. This flexibility makes the process of porting to new areas a difficult parameter optimization problem. In this work we demonstrate our results (and feasible parameter ranges) in application of deep learning methods to structural and functional brain imaging data. We also describe a novel constraint-based approach to visualizing high dimensional data. We use it to analyze the effect of parameter choices on data transformations. Our results show that deep learning methods are able to learn physiologically important representations and detect latent relations in neuroimaging data.


Peer review:
[Review]:
Computation for Section 3.3 have just completed and I have uploaded the revision to arxiv with updated Table 1. Temporarily, while arxiv is processing the paper I am keeping the current version at http://cs.unm.edu/~pliz/iclr2014.pdf