Reviewer ’s report  
 
Title: Radiation therapy for vaginal cancer in complete uterine prolapse: a case report  
 
Version: 0 Date: 11 Mar 2019  
 
Reviewer: Joana Marra  
 
Reviewer's report:  
 
1. The total dose in the first treatment course was about half the total dose delivered to achieve 
tumor response. What was considered to choose the first course dose?  
2. In this particular anatomy setting, with main tu mor volume close to the anterior vaginal wall 
or the urethral exterior meatus, it would be interesting to report  urethral dose for main volumes 
(0.1, 1 and 2cc).  
3. Perhaps a future case update could report late toxicities.  
Best regards,  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to th e authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
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