Reviewer’s report
Title: 
Cancer prevention in females with and without obesity – Does perceived
and internalised weight bias determine cancer prevention behaviour?
Version: 
1 
Date: 
07 Apr 2022
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
OBJECTIVE - Full research articles: is there a clear objective that addresses one
or several testable research questions? (Brief or other article types: is there a
clear objective?)
No - there are minor issues
DESIGN - Is the current approach (including controls and analysis protocols)
appropriate for the objective?
No - there are minor issues
EXECUTION - Are the experiments and analyses performed with sufficient
technical rigor to allow confidence in the results?
No - there are major issues
STATISTICS - Is the use of statistics in the manuscript appropriate?
Not sure - I am not able to assess the statistics in this study
INTERPRETATION - Is the current interpretation/discussion of the results
reasonable and not overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your
concerns sufficiently for you to now recommend the work as a technically sound
contribution? If not, can further revisions be made to make the work technically
sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: Overall the authors have been responsive to previous
critiques. Some problems still remain and it appears the critiques may not have
been fully understood in some cases. The manuscript is interesting but there are
moderate weaknesses that remain
REQUESTED REVISIONS: 
1. I do not think the use of the term "cis" belongs in the title - it should either be
cisgender or biological women or XX women or something to that effort cis is
an abbreviation not well understood. It can be used throughout the manuscript if
defined early on 2. It does not make sense to include this information (pg 3 line
81) in the background when the purpose of the study has not yet been listed. 3. It
is stated the study sought to investigate weight bias and weight bias
internalization, but actual weight bias (which would be a perception from an
external person) does not appear to be measured- perhaps there should be clear
definitions of these variables. 4. Parity refers to the number of children a woman
has had and even the number of pregnancies and the outcomes of those
pregnancy 
- the authors appear to have misunderstood this and it remain
unaddressed. 5. It would have been important to address sexual orientation,
although the numbers of gay/lesbian woman may have been small, it is well
documented that body image can be perceived differently in this community as
well as many misperceptions that cancer screenings are not needed among
women who do not have sex with men. Further, partner status would have been a
key variable to consider as the literature suggests people in relationships are
more likely to encourage one another to receive cancer screenings. 6. The
explanation of the screenings and the healthcare system is very helpful - it does
not appear to take into account family history? Women with a strong family
history of breast or ovarian cancer have different recommendation that are not
based exclusively on age.
ADDITIONAL REQUESTS/SUGGESTIONS: 
The prior reviewer (1) recommended revisions that were not addressed
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
No
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
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Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes