Reviewer’s report
Title: 
Clinical and MRI features of sacral insufficiency fractures after
radiotherapy in patients with cervical cancer
Version: 
4 
Date: 
22 Mar 2022
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
OBJECTIVE - Full research articles: is there a clear objective that addresses one
or several testable research questions? (Brief or other article types: is there a
clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols)
appropriate for the objective?
No - there are major issues
EXECUTION - Are the experiments and analyses performed with sufficient
technical rigor to allow confidence in the results?
No - there are major issues
STATISTICS - Is the use of statistics in the manuscript appropriate?
Not sure - I am not able to assess the statistics in this study
INTERPRETATION - Is the current interpretation/discussion of the results
reasonable and not overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your
concerns sufficiently for you to now recommend the work as a technically sound
contribution? If not, can further revisions be made to make the work technically
sound?
No - manuscript has some fundamental flaw(s)
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: I would like to thank the authors for the revisions.
However, still I believe there is lack of novelty with this paper. The manuscript
doesn't add anything to our current knowledge. Also the methodology is
suboptimal with lack of DWI imaging. I am not sure if any revision can resolve
these inherent limitations
REQUESTED REVISIONS: 
As above
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
No
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes