Reviewer’s report
Title: 
Apatinib treatment is effective for metastatic malignant phyllodes tumors
of the breast: a case report
Version: 
0 
Date: 
14 Apr 2021
Reviewer's report:
In this case report, the authors are providing evidence for effectiveness of
apatinib in treatment of phyllodes tumors.
Please find my comments for consideration by authors:
Avoid abbreviations in the abstract
Review the use of symbols in text (e.g. right mastectomy+sentinel lymph node
biopsy + Latissimus dorsi flap restoration, measuring 17*16*15 cm, others).
They can be better presented as text.
Provide the long-term of abbreviations upon their first appearance in text.
Line 60: what do you mean by HER2 (0)? You mean HER2-negative expression,
0 score by IHC?
Is there any advantage to using apatinib over other angiogenesis inhibitors in
phyllodes tumors? Please add a paragraph discussing the role of angiogenesis
inhibitors in this type of tumors. 
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