Reviewer’ s report
Title: Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysopho-
sphatidic acid receptors in adenomyosis
Version: 0Date: 11 Jul 2017
Reviewer: Akmal El-Mazny
Reviewer's report:
Thank you for giving me the opportunity to review this interesting study "Elevated plasma levels
of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors inadenomyosis".However, I have some comments and recommendations:Comments:Title: - Isappropriate for the content of the article.Abstract: - Represents a suitable summary of thework.Article content: - The design, methods and analysis of the results from the study have beenexplained and are appropriate for the study.Data: - Enough information has been provided in ausable format to be able to replicate the study.Conclusions:- Are sensible, balanced and justifiedon the basis of the results of the study.Recommendations:Introduction:- Be concise and focused;emphasize the gap of knowledge.Methods:- Adequately describe inclusion and exclusion criteria.-Mention appropriate details of diagnostic techniques for adenomyosis.Results:- The text shouldcomplement the tables and figures.- Clarify the effect size for the main outcome.Discussion:-Shorten the size; focus on highly relevant studies.- Mention the limitations of the study.-References:- Shorten the list.- Stick to the format of the journal.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
YesAre the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
AcceptableDeclaration of competing interests
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5. Do you have any other financial competing interests?6. Do you have any non-financial competing interests in relation to this paper?
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If your reply is yes to any, please give details below.
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on my report to the authors and, if the manuscript is accepted for publication, my named reportincluding any attachments I upload will be posted on the website along with the authors'responses. I agree for my report to be made available under an Open Access Creative CommonsCC-BY license (http://creativecommons.org/licenses/by/4.0/). I understand that any commentswhich I do not wish to be included in my named report can be included as confidential commentsto the editors, which will not be published.
I agree to the open peer review policy of the journal