Reviewer’s report
Title: Suitability of MDA, 8-OHdG and Wild-type p53 as Genotoxic Biomarkers in Metal (Co, Ni
and Cr) Exposed Dental Technicians: A Cross-Sectional study
Version: 1 Date: 28 Sep 2019
Reviewer: Mehrnoosh Akhtari-Zavare
Reviewer's report:
Incidence Trend of Breast Cancer in Women of Eastern Mediterranean Region countries from 1998 to
2018: A Systematic Review and Meta-Analysis (BMWH-D-19-00560R1)
Thank you for the opportunity to review this interesting and useful paper. I recommend some changes
to improve the manuscript which are as follows:
1. In introduction need to more information about prevalence of BC, age of onset BC, in EMR?
2. In methodology part need more explanation about "JBI (The Joanna Brigge Institute) checklist and
risk assessment checklist", 
Items and what is the name of scales for given score 0-10, 
How check their validity and reliability?
Who fill up checklist?
How control the bias?
3. Add the flow chart for methodology for better understanding and following method?
4. Result and discussion are acceptable
5. What is the recommendation for further study?
I hope that this information is useful to the editors and authors. Finally, to draw a conclusion, I believe
the authors should do the above minor corrections before you publish it.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?
If an additional statistical review is recommended, please specify what aspects require further
assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
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organisation that may in any way gain or lose financially from the publication of this
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financially from the publication of this manuscript, either now or in the future?
3. Do you hold or are you currently applying for any patents relating to the content of the
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds
or has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?
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If your reply is yes to any, please give details below.
I declare that I have no competing interests
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