Reviewer’ s report
Title: LncRNA GATA6-AS inhibits cancer cell proliferation and promotes cancer cell apoptosis in
cervical cancer by down-regulating miR-205
Version: 0Date: 26 Aug 2019
Reviewer: Hao Xu
Reviewer's report:
1.This study found that GATA6-AS may inhibit cancer cell proliferation and promote cancer cell
apoptosis in CSCC by downregulating miR-205. This is meaningful, but there are also someproblems in this paper.2.This study describe the relationship between lncRNA and cancer in the introduction part.Is therea need to supplement the research progress of the relationship between lncRNA and cervicalcancer? In order to give a full explanation of its research significance, the mechanism of GATA6-AS in tumors can be more fully described in this paper.3.It is of great significance to choose miR-205 to study,but why is miR-205 not described in theintroduction?4.There are some spelling errors and some grammatical problems.It needs experts who speakEnglish as their mother tongue to polish it up!
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
YesAre the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being publishedDeclaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an
organisation that may in any way gain or lose financially from the publication of this
manuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose
financially from the publication of this manuscript, either now or in the future?
3. Do you hold or are you currently applying for any patents relating to the content of the
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds
or has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below.
If your reply is yes to any, please give details below.
I declare that I have no competing interests
I agree to the open peer review policy of the journal. I understand that my name will be included
on my report to the authors and, if the manuscript is accepted for publication, my named reportincluding any attachments I upload will be posted on the website along with the authors'responses. I agree for my report to be made available under an Open Access Creative CommonsCC-BY license (http://creativecommons.org/licenses/by/4.0/). I understand that any commentswhich I do not wish to be included in my named report can be included as confidential commentsto the editors, which will not be published.
I agree to the open peer review policy of the journal