JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022
Version: 1 Date: 19 Oct 2024
Reviewer:  Amany H Refaat
Reviewer's report:
Dear authors,
Thank you for sharing this interesting study for publication. I have the following comments:
1- As you covered in your introduction, the study's topic is well studied in previous research.
You may want to add the rationale for conducting this study and what is the gap of knowledge
it will cover.
2- The DHS collects data on 4 types of IPV: emotional, less severe physical, severe physical,
and sexual.  Please kindly elaborate on your choice of using 3 only.
3- in Table 1: mean age with SD expression need review since SD usually is expressed by lower
and upper limits.
4- What is the source of Fig 1? Did you devlop it  by geosapatial analysis or you get it from
another source (citation?`). You did not explain it or comment on it in teh results too.
Best of luck
Title: Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022
Version: 3 Date: 03 Dec 2024
Reviewer:  Amany H Refaat
Reviewer's report:
Dear authors,
Thank you for responding to reviewers comments. Please change the parity in tables to 5+ more
instead of the high figure of 5-17.
Best of luck
Title: Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022
Version: 3 Date: 11 Dec 2024
Reviewer's report:
Thank you for the revised manuscript and clear response sheet to reviewer’s comments. My
comments on some of the responses and actions are in the attached file.
My comments and suggestions on the revised manuscript are included in the file manuscript
itself.
Title: Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022
Version: 3 Date: 14 Dec 2024
Reviewer's report:
The manuscript tackles a public health issue by analyzing IPV prevalence and associated factors
using recent and robust data. The study’s findings are relevant and actionable, particularly for
policymakers in Tanzania and similar contexts. However, the manuscript requires revisions to
improve clarity, deepen the literature review, and better contextualize findings. These changes
are moderate but necessary for enhancing the overall impact and readability of the study. I
recommend acceptance pending these revisions.
Title: Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022
Version: 4 Date: 03 Jan 2025
Reviewer:  Amany H Refaat
Reviewer's report:
Dear authors,
Thank you for responding to almost all of my comments. Your study is a much stronger one
now. However, I still have the following comments:
1- You mentioned in the methodology that the main variable of women's empowerment is
measured as "A binary variable for women’s empowerment (empowerment) was created to
test the direct influence of women's empowerment on IPV. Empowerment was assessed based
on decision-making participation and rejection of wife-beating. Women were classified as
"empowered" if they participated in decisions regarding their own health care, large household
purchases, and visits to family or relatives, either alone or jointly with their husbands, and
rejected all justifications for wife-beating. Women not meeting both criteria were classified
as "not empowered,".  However, you described only the decision-making participation under
women's autonomy.  Where is the rejection of justification of IPV?
2-  Please show the prevalence of empowered women too.
Best of luck
Title: Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022
Version: 6 Date: 20 Mar 2025
Reviewer:  Zacharie Tsala Tsala Dimbuene
Reviewer's report:
Review report:
Title: “Prevalence and factors associated with Intimate Partner Violence among women in
Tanzania: Evidence from Tanzanian Demographic and Health Survey 2022È
Authors:
• Pankras Luoga
• Siri A. Abihudi
• Jovinary Adam
• Magreth Thadei Mwakilasa
Comments:
The paper addressing an interesting topic regarding intimate partner violence in a context where
women and girls are not fully protected despite the exiting legal frameworks and cultural norms.
The paper however, treats the three forms of IPV (physical, emotional, and sexual) as a single
item resulting in yes/ no. I wonder why the authors didn’t do any efforts to examine these
components separately and test whether these three types of IPV are driven by same social
forces?
Major comments:
I am a bit concerned by the methodology used in the paper, especially by the fact that the authors
used a sub-sample of married/cohabiting women, yet they didn’t state clearly how this approach
and using complete-case analyses could affect the estimates (especially, variances necessary to
compute 95% CI)?
I have included in the annotated manuscript a link from UCLA which explains how to conduct
analyses on sub-populations, as it is the case in the paper.
Minor comments:
The authors mention that women’s and hubby/partner’s age are strongly correlated. However,
they were equally included in the analyses without further statistical implications/considerations.
I have suggested to include instead “age differences” between spouses to account for the effect
of hubby/partner’s age if this latter is not correlated with women’s age.
Decision: Major Revision
Title: Insufficient Knowledge of Human Papilloma Virus among Reproductive-Aged Women
from Arak, Iran
Version: 3 Date: 30 Mar 2023
Reviewer's report:
Hello,
We need to consider why there is a lack of information about HPV among Iranian people
in studies. We must make greater efforts to increase public awareness, which can help
prevent HPV-related diseases. All organizations and the government should collaborate to
raise awareness through effective advertising and education, so that individuals become more
informed about HPV-related issues. We must try to identify high-risk populations and help
them better protect themselves, for example, by organizing mass vaccination campaigns. These
solutions can help reduce the incidence of HPV-related diseases, and it's the best we can do for
the Iranian community.
Please consider the question of why there is a lack of information about Human Papillomavirus
(HPV) in Iranian studies? More effort is needed to increase public awareness and prevent
the spread of this virus. It is of great importance for all organizations and governments to
promote effective advertising and education to the public. Additionally, mass vaccination can
significantly reduce HPV-related diseases. Therefore, it is necessary for the community to
cooperate to emphasize the prevention and management of this virus.
Thank you to the author of the article for presenting this important issue.
As far as the opinion is concerned, the p-value is not mentioned in the table, which needs to be
corrected. It is important to investigate this.
Title: Insufficient Knowledge of Human Papilloma Virus among Reproductive-Aged Women
from Arak, Iran
Version: 7 Date: 27 Sep 2024
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
No - there are issues with the statistics in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
No - there are major issues
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Maybe - with major revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: In their present revised version, authors have addressed part of
previously raised concerns. However, i believe some issues deserves further attention
REQUESTED REVISIONS:
The methodological approach is still an issue. If authors decide to use an arbitrary threshold to
define “insufficient”HPV vaccine knowledge that is ok (as long as you cite a previous similar
study applying the same approach and discuss that in the limitation section). However, authors
should seek advice from a senior statistician to run a multivariate model adjusting for potential
confounders.
« if a person did not sign the informed consent, was not included in the study. Nevertheless, they
were very limited.” Authors should clearly state in their result section how many participants
were solicited to contribute and how many were not part of the analysis and for what reasons.
Title: Insufficient Knowledge of Human Papilloma Virus among Reproductive-Aged Women
from Arak, Iran
Version: 8 Date: 06 Mar 2025
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
No - there are issues with the statistics in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Maybe - with major revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: In their present revised version, authors have only partly addressed
my previous comments. There are still unclear elements related to the statistical approach.
REQUESTED REVISIONS:
Authors stated that "Quantile regression was employed to account for potential confounding
factors." That statement lacks of details on how the multivariable analysis was effectively
conducted. Quantile regression is not an usual regression model used in health science compared
to linear regression model as I supposed authors are considering a continuous variable as their
variable of interest. Therefore, authors need to expand more (with reference) why and how
the used this modelling approach. What was the variable of interest, considered? explanatory
variable? Why they were considered and Which strategy was applied to select a final model.
This should complete the statistical analysis section.
Title: Does Adenomyosis Influence Tumor Characteristics and Survival in Endometrioid-Type
Endometrial Cancer?
Version: 2 Date: 22 Apr 2025
Reviewer's report:
This is a well-structured and clinically relevant study exploring the association between
adenomyosis and tumor aggressiveness in endometrioid-type endometrial cancer. It adds
meaningful data to an area with mixed findings in the literature.
However, the following areas could be improved:
1. The current title is fine, but a question-style or slightly more specific title can be more
engaging.
2. The abstract should report key statistics, including % reduction in lymphovascular invasion,
p-values for survival difference and an zctual 5-year survival numbers in both groups. Add a
clearer statement of the main conclusion.
3. In the methodology section,
a) Clarify staging: Were all patients FIGO-staged? Add that info.
b) Frozen section policy has been described in detail but can be slightly condensed.
c) Consider explaining why para-aortic lymphadenectomy was omitted in certain cases.
d) Some terminology needs consistency: e.g., "gravity" should be "gravidity"
e) Is “scientific data” meant to be “clinical data”?
4. In the results section,
a) Include confidence intervals with survival data.
b) In survival comparison: "The rate was higher but not statistically significant", could be better
quantified (e.g., HR, CI, p-value).
c) Rephrase: “Patients with adenomyosis had a higher number of pregnancies and deliveries”
5. For Tables and Figure
a) Table 1 and Table 2: Should be included directly in the manuscript or supplementary files
(they are referenced but not visible).
b) Figure 1 (Kaplan-Meier curve): Needs clearer labeling (axes, group names, p-value display).
c) Consider adding a Table 3 summarizing key pathological features with corresponding odds
ratios or percentages.
6. In the Discussion section, consider adding:
a) The potential influence of hormonal exposure or HRT on adenomyosis/EC interplay.
b) More elaboration on the lack of survival significance: could it be due to short follow-up, low
event rate, or treatment parity between groups?
c) Reconsider repetition: "less aggressive tumor characteristics" is used many times.
Title: Does Adenomyosis Influence Tumor Characteristics and Survival in Endometrioid-Type
Endometrial Cancer?
Version: 2 Date: 23 Apr 2025
Reviewer's report:
Dear Authors
I would like to express my gratitude to the authors for their dedication.
Your article is a current investigation that is in accordance with the existing body of literature.
I recommend that you enhance the quality of your article's writing.
Kind Regards
Title: A Study on Early Marriages and Pregnancy Health in The South-Eastern Region 0f
Türkiye
Version: 3 Date: 11 Apr 2025
Reviewer's report:
This manuscript addresses an extremely important and sensitive topic—the issue of early
marriages and their impact on women’s reproductive health and well-being. The study sheds
light on the serious negative consequences of early pregnancies, including health complications
that can threaten the lives of young mothers. The lack of adequate medical care and low health
awareness, often seen in these cases, further exacerbates the risks and underscores the urgency
of the problem.
The introduction and discussion sections are well-written and clearly establish the context,
relevance, and implications of the research. The study provides insightful and meaningful
perspectives from the women affected, giving voice to their lived experiences and emphasizing
the cultural and societal structures that perpetuate early marriages.
The themes identified—ranging from the family-driven nature of early marriage to the
challenges of young motherhood—are both powerful and thought-provoking. They help the
reader understand not just the individual impacts but also the broader socio-cultural dynamics
involved.
However, I must note that I am not in a position to fully evaluate the methodological aspects
of the study, particularly the use of phenomenological design and deductive content analysis,
due to my limited experience with qualitative research techniques. That said, the presentation
of the findings appears coherent and grounded in the data, and the conclusions are appropriately
formulated and consistent with the results.
In sum, this is a valuable and timely contribution to the literature on women’s health and human
rights. The topic is highly relevant for public health, gender equity, and education policy, and I
believe this work deserves to be shared with a broader audience.
I recommend the manuscript for publication, with only minor editorial revisions if needed.
Title: Metabolism-associated marker gene-based predictive model for prognosis, targeted
therapy, and immune landscape in ovarian cancer: An integrative analysis of single-cell and bulk
RNA sequencing with spatial transcriptomics
Version: 4 Date: 18 Aug 2024
Reviewer's report:
The present is an experimental stidy aimed to assess a prognostic model constructed through
the combined analysis of glucose metabolism, lipid metabolism, choline metabolism, and
sphingolipid metabolism. The study is weel-done but the Authors should explain such terms for
a better understanding of research value.
The abstract include terms, such as “AddModuleScore” or “Seurat package that should be
explaired for readers not so expert in the field.
The sample size (the samples studied) seem very little. This makes valid the findings. Please
explain the potential validity and variability of the findings or the little sample may reduce the
external validity of your results.
Have you tested the robustness of your data in different laboratories?
Have you test the intra-operator and inter-operator coefficient of variation fo your results?
Have you analyzed your data using the artificial intelligence?
More detail about the characteristics of the patients should be provided.
The discussion should be revised introducing also clinical notes. Have you tested your results
in the clinical practice?
Title: Metabolism-associated marker gene-based predictive model for prognosis, targeted
therapy, and immune landscape in ovarian cancer: An integrative analysis of single-cell and bulk
RNA sequencing with spatial transcriptomics
Version: 5 Date: 23 Mar 2025
Reviewer's report:
The authors of ‘Metabolism-associated marker gene-based predictive model for prognosis,
targeted therapy, and immune landscape in ovarian cancer: An integrative analysis of single-
cell and bulk RNA sequencing with spatial transcriptomics’  have devoted substantial effort
to addressing the points of the prior review, and in general the manuscript is now suitable for
publication, with a few minor points described below that can be easily addressed.  I will,
however, take exception to their argument that ‘allocation of resources’ precluded them from in
vitro and in vivo validation of their assertions regarding ATGR2 and cardesartan, on the simple
observation that equivalent resources were dedicated to the study of TREM1.  Had they chosen
to relegate TREM1 to a separate study, as they propose to do for ATGR2 in their reply, then the
resulting manuscript would have been far more coherent and compelling.
Minor concerns:
1. The acronyms ‘HRG’ and ‘LRG’ need to be defined at first use, on page 11. This is particularly
needed given that the acronym ‘MRG’ is highly similar, but instead refers to ‘metabolism related
genes’.  I am assuming HRG and LRG refer to High Risk Group and Low Risk Group, but that
is never explicitly stated.
2. When the focus on TREM1 is first introduced on page 24, the assertion that it
is a ‘prognostically significant gene related to metabolism’ needs to be supported with
REFERENCES. The references currently listed as #45 and #46 could be cited, and then described
in greater detail in the Discussion section where these references are currently first introduced.
3. On page 14 and in the figure legend to Figure 13, ‘WT’ is not defined.  Moreover, Figure
13 panels C, D, and E refer to a control ‘shNC’ which is never defined anywhere. Is ‘WT’
untransfected, and ‘shNC’ transfected with a non-coding shRNA? One can infer that, but one
should NEVER be asked to interpret data on the basis of inference. Ideally, the Methods section
should also contain the sequence of both the shTREM1 and the shNC constructs.
4. References 49 and 50 (published in 2015 and 017) are significantly out of date regarding the
fallopian tube versus ovary debate regarding the origin of high grade serous ovarian carcinoma.
See for example Greenwood A, et al. Obstet Gynecol. 2024. PMID: 38176019
Title: MCT-modified Ketogenic Diet as an Adjunct to Standard Treatment Regimen Could
Alleviate Clinical Symptoms in Women with Endometriosis
Version: 2 Date: 12 Apr 2025
Reviewer's report:
1. The study exclusively enrolled women with stage I and II endometriosis, which limits the
generalizability of findings to those with moderate to severe disease (stages III and IV). This
limitation should be explicitly acknowledged and discussed as a direction for future studies.
2. The narrow inclusion criteria for age (25–35 years) and BMI (21–25 kg/m²) may limit the
external validity of the study. Consider noting that the findings may not apply to populations
with overweight/obesity or older reproductive-age women. Acknowledge this limitation.
3. The discussion refers to inhibition of Wnt/#-catenin signaling as a possible mechanism, but
the study did not measure any molecular or inflammatory markers. This should be clearly noted
as a theoretical explanation, not a demonstrated outcome in this trial.
4. Given the anti-inflammatory hypothesis of the ketogenic diet, it is a missed opportunity not
to measure biomarkers such as CRP, IL-6, or TNF-#. This limitation should be acknowledged
and used to justify future research priorities.
5. The manuscript states that the diet "significantly alleviated pelvic pain", yet the reported
p-value is 0.07. This should be reframed as a "marginal" or "trend-level" finding to avoid
overstating the result.
6. It is recommended that the discussion section of this paper highlight the importance
of incorporating validated quality of life assessment tools such as the SF-36 or EHP-30
questionnaires to evaluate the broader impact of the dietary intervention on patients’ well-being.
Title: MCT-modified Ketogenic Diet as an Adjunct to Standard Treatment Regimen Could
Alleviate Clinical Symptoms in Women with Endometriosis
Version: 2 Date: 15 Apr 2025
Reviewer's report:
I would like to thank the authors for the opportunity to review this well-written and clinically
meaningful study. The manuscript addresses a relevant topic in women's health and presents
promising preliminary findings. I offer the following comments for the authors' consideration.
1. The authors are encouraged to provide a clearer rationale for the selection of the MCT-
modified ketogenic diet, rather than a general ketogenic diet, in the Introduction section.
Elaboration on the specific characteristics or hypothesized advantages of the MCT-based
approach in the context of endometriosis would strengthen the background and help justify the
intervention choice.
2. Details regarding the overall duration of the study, including the intervention period and
follow-up schedule, should be clearly described. This would improve the transparency and
reproducibility of the trial methodology.
3. In Table 4, the authors have appropriately presented baseline values, post-treatment values,
and change-from-baseline (#) values for both groups. However, in the main text, only
the between-group comparison of post-treatment values is discussed. It is generally more
appropriate in interventional studies to compare the change-from-baseline values between
groups, rather than comparing post-treatment values alone, in order to better reflect the net effect
of the intervention. Revising the analysis description in the Results section accordingly would
improve the clarity and validity of the interpretation.
4. In addition, the outcome for pelvic pain did not show statistical significance in either the
post-treatment comparison or the between-group change. This point should be more clearly
acknowledged and interpreted in the Results and Discussion sections to avoid overstating the
clinical impact.
Title: Prevalence of Depression and Anxiety among Working Women in Saudi Arabia:
Psychosocial and Perinatal Correlates
Version: 2 Date: 21 Sep 2024
Reviewer:  Enas Mahrous Abdelaziz
Reviewer's report:
In reviewing the remarkable contributions of your efforts , I am truly inspired by the dedication
and passion to each one  brings to their work. It's evident that every task is approached with
meticulous attention to detail and a genuine desire to excel.