JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Predicting cervical cancer screening behavior among women in southern Iran: A cross-
sectional study with PEN-3 model
Version: 0 Date: 18 Apr 2023
Reviewer:  Ilaria Cuccu
Reviewer's report:
In my opinion, the analyzed topic is interesting enough to attract the readers’ attention. The
goal of this  article was to predict cervical cancer screening behavior with PEN-3 model among
women residents of Bandar Abbas. I think that the abstract of this article is well organized and
clear. In my opinion, the discussion could be studied in depth and extended. Maybe, it could be
useful the evaluation of the state of the art of early stage surgery and postoperative outcomes
in order to sensitize women to screening protocols. In particular I suggest these two articles
PMID: 36141917 and PMID: 35909005. Because of these reasons, the article should be revised
and completed. Tables are clear. Considered all these points, I think it could be of interest for
the readers and, in my opinion, it deserves the priority to be published after minor revisions.
Title: Predicting cervical cancer screening behavior among women in southern Iran: A cross-
sectional study with PEN-3 model
Version: 2 Date: 04 May 2023
Reviewer:  Ilaria Cuccu
Reviewer's report:
I read with great interest the Manuscript titled " Predicting cervical cancer screening behavior
among women in southern Iran: A cross- sectional study with PEN- 3 model” , topic interesting
enough to attract readers' attention.
The quality of the manuscript has improved thanks to the changes made. The methodology
is accurate, and conclusions are supported by data analysis. The discussions are clear and
comprehensive.
Considering all these points, I think it could be of interest to the readers and, in my opinion, it
deserves the priority to be published.
Title: Urinary phytoestrogens and the risk of uterine leiomyomata in US women
Version: 0 Date: 15 Feb 2023
Reviewer's report:
Lines 24-26: How to use the "weighted" method?
Please add a description of how to combine four cycle data (NHANES 1999-2000, 2001-2002,
2003-2004, 2005-2006).
There is an inconsistency between the lines 123-132 and the lines 151-157 and the Supplemental
Table.
Please provide actual P values, such as lines 169 and 173.
As shown in Table 2, consider the potential causes why there was not statistical significance
of equol in model 1, but statistical significance in model 2 and model 3, and the protective
efficiency of enterolactone in model 1.
Based on Table 3, interpret the causes of only selecting positive associations between urinary
phytoestrogen and UL in lines 177-182.
In Supplemental Table 3, is it appropriate to introduce BMI, waist circumference, cotinine, age
at menarche directly into the logistic regression?
Spelling and grammar must be checked carefully.
There must be revision to the discussion, such as comparing it with other studies, and providing
more information about mechanisms.
Please check carefully the conclusions of this study, for example lines 203-204.
Title: The Survival Impact of Adjuvant Radiotherapy and Chemotherapy in Patients with Non-
endometrioid Endometrial Carcinomas: a PSM-IPTW Analysis Based on SEER Database
Version: 2 Date: 23 Apr 2023
Reviewer's report:
The present study enrolled 5,577 non-endometrioid endometrial carcinomas (NEEC) patients
and investigated impact of combined chemotherapy and radiotherapy (CRT), chemotherapy
alone, and radiotherapy alone after surgery on overall survival and cause-specific survival.
Stratified by radiotherapy administrated or not, propensity score matching (PSM) method
was employed to explore effect of radiotherapy on NEECs. Supplementary Table 1. showed
two cohorts after IPTW-adjusted by postoperative chemotherapy or not and by postoperative
radiotherapy or not. Please demonstrate which or both cohorts were explored for further analysis,
as survival analysis of predicting CSS and OS after IPTW-adjusted by CRT or RT and by CRT
or CT. However, the first line in table 3 displayed the CRT or RT alone, which is confusing.
Subgroup analysis was used to explore postoperative adjuvant treatment impact on survival
outcome in the whole cohort and sensitivity analysis for patients with serous and clear cell
histology at different TNM stages were performed. Please demonstrate the purpose of sensitivity
analysis in the statistical analysis section and the methods used, such as changing different
cutoff value of covariates, different subgroup population and subgroup analysis. The sensitivity
analysis proved the estimated effect in the primary analysis or not? Please indicate the current
conclusion is robust or not and discuss it in discussion section.
The important factors affecting OS and CSS for different cohorts should be analyzed in the
discussion section.
Language needs to be further improved, for example, epifacial total hysterectomy, distal
metastasis, et al.
Title: The Survival Impact of Adjuvant Radiotherapy and Chemotherapy in Patients with Non-
endometrioid Endometrial Carcinomas: a PSM-IPTW Analysis Based on SEER Database
Version: 2 Date: 23 Apr 2023
Reviewer's report:
In my opinion, the analyzed topic is interesting enough to attract the readers’ attention. The
goal of this  article is to investigate outcomes of adjuvant treatments for non-endometrioid
endometrial carcinomas . I think that the abstract of this article is well structured and clear.
In my opinion, the discussion could be studied in depth and extended. Maybe, it could be useful
the evaluation of the state of the art of possible new ways of management of endometrial cancer
analyzing also its molecular aspects. In particular I suggest these two articles  PMID: 36833105
and PMID: 36983243. Because of these reasons, the article should be revised and completed.
Tables are interesting. Considered all these points, I think it could be of interest for the readers
and, in my opinion, it deserves the priority to be published after minor revisions.
Title: The Survival Impact of Adjuvant Radiotherapy and Chemotherapy in Patients with Non-
endometrioid Endometrial Carcinomas: a PSM-IPTW Analysis Based on SEER Database
Version: 2 Date: 23 Apr 2023
Reviewer:  Ilaria Cuccu
Reviewer's report:
In my opinion, this topic analyzed is interesting enough to attract readers’ attention. The goal of
this study is to investigate outcomes of adjuvant treatments for non-endometrioid endometrial
carcinomas (NEEC).
Methodology is accurate and conclusions are supported by the data analysis. Nevertheless,
authors should clarify some points:
- I suggest a round of language revision, in order to correct few typos and improve readability.
- It would be interesting to discuss results of this study in the scenario of the current molecular
classification and recent evidence present in the literature of endometrial cancer (In particular,
I suggest this article to get deeper in the topic PMID: 36979434).
- The authors should discuss solid evidence on the use of new strategies for management of
endometrial cancer. For example, you might consider using artificial intelligence, especially
radiomic analysis of radiological images. (In particular, I suggest this article to get deeper in
the topic PMID: 36553988)
Because of these reasons, the article should be revised and completed. Tables and figures are
clear and interesting. Considering all these points, I think it could be of interest to the readers
and, in my opinion, it deserves the priority to be published after minor revisions.
Title: The Survival Impact of Adjuvant Radiotherapy and Chemotherapy in Patients with Non-
endometrioid Endometrial Carcinomas: a PSM-IPTW Analysis Based on SEER Database
Version: 4 Date: 06 May 2023
Reviewer:  Ilaria Cuccu
Reviewer's report:
I read with great interest the Manuscript titled " The Survival Impact of Adjuvant Radiotherapy
and Chemotherapy in Patients with Non-endometrioid Endometrial Carcinomas: a PSM-IPTW
Analysis Based on SEER Database”, topic interesting enough to attract readers' attention.
The quality of the manuscript has improved thanks to the changes made. The methodology
is accurate, and conclusions are supported by data analysis. The discussions are clear and
comprehensive. References are relevant to the search
Considering all these points, I think it could be of interest to the readers and, in my opinion, it
deserves the priority to be published.
Title: The Survival Impact of Adjuvant Radiotherapy and Chemotherapy in Patients with Non-
endometrioid Endometrial Carcinomas: a PSM-IPTW Analysis Based on SEER Database
Version: 4 Date: 10 May 2023
Reviewer's report:
I wanted to thank the authors for making the requested changes and thus broadening and
clarifying the discussion. Thanks to these modifications the article is much more flowing and
clearer and that's why it is deserves the priority to be published
Title: Stage IIB-IVA Cervix Carcinoma in Elderly Patients Treated with Radiation Therapy: A
Longitudinal Cohort Study by Propensity Score Matching Analysis
Version: 3 Date: 15 Mar 2023
Reviewer:  Kosuke Yoshida
Reviewer's report:
In the present study, the authors investigated the overall survival of elderly patients with uterine
cervical cancer. This is one of the large-scale studies; therefore, this study would benefit
gynecologists. However, there were several concerns, and the detailed comments are following.
1. In the entire cohort, the authors showed that the prognosis of elderly patients was poorer than
that of young patients. Did the authors evaluate the prognosis by stratifying with the FIGO stage?
I think that the Kaplan-Meier curves for each stage may provide more beneficial information.
2. In Figure 3, even in the patients who received trimodal therapy, the prognosis of the elderly
patients was poor. What are the potential reasons for this?
3. Can the authors evaluate other prognostic parameters, such as progression-free survival or
cancer-specific death, in this dataset?
Title: Stage IIB-IVA Cervix Carcinoma in Elderly Patients Treated with Radiation Therapy: A
Longitudinal Cohort Study by Propensity Score Matching Analysis
Version: 3 Date: 11 Apr 2023
Reviewer's report:
In this paper, Shou et al. investigated the treatment modality and the prognostic impact of age
at diagnosis on stage IIB-IVA cervical carcinoma.  They retrospectively analyzed the SEER
database,  showing that older patients were less likely to receive aggressive treatments and
their prognosis was worse.  The study is interesting because the elder population is increasing,
however, there are several limitations. The data are collected from 2004 to 2016, a very extensive
time frame.  Indeed, in this period of time, cervical cancer treatment has been completely
revisited.  Further details would be necessary to be able to compare the two populations.
Furthermore,  the 2016 FIGO classification was considered in the paper, and this makes the
results not applicable in current clinical practice. For this reasons, I would suggest rejecting this
manuscript.
Title: Trust in the provider  and accurate self-reported PrEP adherence among adolescent girls
and young women in South Africa and Zimbabwe: HPTN 082 study
Version: 1 Date: 14 Mar 2023
Reviewer's report:
The current study examines the association between trust in providers and adherence to pre-
exposure prophylaxis (PrEP) and accurate reporting of adherence.  The study enrolled youth and
young adults (ages16-25 years) from South Africa and Zimbabwe.  Overall, it is a well written
paper addressing an important issue.  Increasing adherence to PrEP would help in reducing HIV
exposure.  There are a few areas that require clarifications as follows:
1. Methods
• The authors should mention whether or not parental consent was required for minors.  It would
also be helpful to indicate if minors in these countries can access PrEP without parental consent.
• The authors provide a reference for the Epidemiologic Studies Depression Scale.  However,
there is no reference to the provider trust scale.  The authors mention the Sandford Trust in
Physician Scale, a 10-itme scale. The author should provide a rationale for the selection of three
items.  Also, the authors do not provide a reference for the HIV risk perception.  It would be
helpful to mention how these scales/questions fit a youth population.
2. Results
• The authors report the results for both countries combined.  Did the authors conduct an analysis
per country? Are there differences between the countries that will justify a separate analysis?
The authors should briefly comment on their decision to provide aggregated results.
3. Discussion
• The sentence “May improve understanding of trust factors” in the context of the sentence on
line 248 is unclear.  Please clarify who will understand trust factors. Also, it would be helpful
to describe the constructs of the scale before commenting on its usefulness.
• The authors recommend the development of a culturally sensitive trust questionnaire.
However, addressing cultural aspects of care by providers is not addressed.  It would be helpful
to integrate it in describing a youth friendly environment.
• The authors include an extensive discussion about reasons for discordant adherence and include
several references.  However, in the introduction they state there is limited research on whether
patients are transparent about their PrEP adherence.  The authors should describe the results of
the limited research in the introduction.  This will also help in reducing the long discussion in
the discussion section.
• Are the same recommendations relevant for both countries?
• The authors should comment in the limitations section about the implications of using only
three times to assess provider trust.
Title: Trust in the provider  and accurate self-reported PrEP adherence among adolescent girls
and young women in South Africa and Zimbabwe: HPTN 082 study
Version: 1 Date: 25 Mar 2023
Reviewer's report:
Authors, please apply the following comments.
1. The title is long.
2. The Methods section in the abstract should be modified so that the following items are
included: type of study, number of participants, study time, sampling method and follow-up
times, tools used, statistical methods, software used.
3. In the Background section (in the main text), about trust, which is the main variable, and the
ways to acquire it, should be explained more.
4. In the Methods section (in the main text), express inclusion and exclusion criteria, the type
of study and the sampling method, please be clearly stated.
Title: Reasons For Modern Contraceptives Choice and Long-Acting Reversible Contraceptives
Early Removal In Amhara Region, Northwest Ethiopia; Qualitative Approach
Version: 3 Date: 09 Feb 2023
Reviewer:  Ottavia D'Oria
Reviewer's report:
In my opinion, this topic analyzed is interesting enough to attract readers’ attention.
-The abstract of this article is not very clear and a bit too long. So I think that the abstract should
be completely rewritten in order to better summarize the contents of the manuscript.
-The results are not very clear and too confusing. I think that those should be reorganized. I think
that should be important also evaluate contraception after surgery. Because of that, i think that
the discussion could be expanded with this article: PMID: 26364832 .
-In my opinion, the discussion could be for this reasons studied in deep and extended.
-Moreover, an extensive correction of the English language is necessary in order to make the
work clearer and more readable.
-Tables’ layout should be improved .
-Article’s layout could be improved, especially the references part.
Because of these reasons, the article should be revised and completed.
Considered all this points, I think it could be of interest for the readers and, in my opinion, it
deserves the priority to be published after major revisions.
Title: Reasons For Modern Contraceptives Choice and Long-Acting Reversible Contraceptives
Early Removal In Amhara Region, Northwest Ethiopia; Qualitative Approach
Version: 3 Date: 19 Feb 2023
Reviewer:  Davide Coldebella
Reviewer's report:
I read your article with interest because it represents a very different reality from the one in which
I’m working in Italy. The use of different contraceptives is closely linked to the culture of a
country, in addition to the different economic possibilities. European or American guidelines or
counselling cannot be applied without thinking the specificity of your country. So it is essential
to collect local data to guide regional policies towards the objectives you mentioned (FP 2020
Sustainable Development Goals). Since the size of the exploratory sample is low, I think it has
been effective to use people's words to better understand the cultural context that guides the
choices of the contraceptive method.
I suggest preparing a table that presents the results (reasons for contraceptive choice and reasons
for discontinuing the LARC) in a more schematic and straightforward way.
Title: Knowledge, attitude, and uptake of human papillomavirus vaccine among adolescent
schoolgirls in Ethiopia: A systematic review and meta-analysis
Version: 0 Date: 24 Jan 2023
Reviewer:  Minwuyelet Maru Temesgen
Reviewer's report:
This is an interesting review and is generally well structured. However, in my opinion, the paper
has shortcomings in regard to the text and the analysis part. Below I have provided some remarks.
• Grammatical and spelling errors and unnecessary repetitions and wordings
• Result: A high percentage of Heterogeneity is reported in the meta-analysis, and this is not a
problem by itself if it is justified. But I haven’t seen a description or reasons and it is mandatory
to do so
• Result: Page 11, Figure 4: If the P-value is 0.000, it should be written as P-value  < 0.001 and
No spacing between columns
• Discussion: It should describe detailed reasons for variations between compared findings
between different countries as the setting of these countries vary from Ethiopia
• Discussion should also include a study from Tanzania because Ethiopia and Tanzania are the
two countries that introduced 14 years of girls’ vaccination from Africa.
Title: Knowledge, attitude, and uptake of human papillomavirus vaccine among adolescent
schoolgirls in Ethiopia: A systematic review and meta-analysis
Version: 2 Date: 05 Apr 2023
Reviewer's report:
Thank you for submitting the revised manuscript” Knowledge, attitude, and uptake of human
papillomavirus vaccine among adolescent schoolgirls in Ethiopia: A systematic review and
meta-analysis” to BMC Women's Health.
Some additional revisions are suggested as follows:
Please compare your results to those of other studies that have been conducted on the same/
similar topic, and highlight similarities and differences between your findings and those of other
researchers with supporting evidence.
Discussion:
On pages 18-19, "The variation in the level of knowledge could be attributed to differences in
governmental concern, media coverage, and public concerns about cervical cancer and the HPV
virus across countries. In addition, disparities in HPV-focused educational programs and data
collection periods between the two countries may contribute to these gaps".  Please provide a
more detailed description of the information contained in this sentence and include appropriate
citations as necessary.
On page 19, "This finding was also in line with a meta-analysis study in high and low-income
countries, which was 41.5% [39]". Please provide a more detailed explanation of the value being
referred to and how it varies between countries with high and low income.
On page 19, "This discrepancy might be due to variations in vaccine delivery strategies. In
Ethiopia, the vaccine is delivered through a school-based approach to reach all 14-year-old
girls. The higher uptake rates in this study imply that a school-based strategy can remove
some obstacles and raise the possibility that adolescents will enroll in the program. " Please
provide a more elaborate explanation of how the vaccine delivery strategies differ, along with
the corresponding rationale, not only within Ethiopia but also in other settings.
On page 19, "This could be due to differences in the accessibility of the vaccine, with relatively
low access coverage in Ethiopia." Please elaborate on the differences in vaccine accessibility
and provide the rationale for the differences.
On page 19, "Moreover, the difference might be attributable to variations in HPV vaccination
policies between the two countries, where HPV vaccination programs are restricted to low age
groups of females (ages 9–14 years) in Ethiopia. " Please further describe and provide the
rationale for the differences in HPV vaccination policies.
Title: Knowledge, attitude, and uptake of human papillomavirus vaccine among adolescent
schoolgirls in Ethiopia: A systematic review and meta-analysis
Version: 2 Date: 09 Apr 2023
Reviewer's report:
Most of my concerns on the previous review were addressed but some are missed.
Pooled estimate:
As the study is a meta-analyses, can you predict the possible probability (range of result) for any
future study regarding the research question in the study area.
sensitivity analysis
During your analysis, the software will remove one paper at a time, yes. That is the problem.
You need to do analysis by removing more tan one paper at a time.
What is the intake from sensitivity analysis?  For example you have presented result on table 3.
in the first section when Geneti et al (2016) & Bulto et al (2021) are removed there is a change
in the pooled estimate with more than 5 digits.
You need to present the I2 in the table to indicate change in heterogeneity
Figure 2 and 3 needs edition
please include cumulative analysis after sorting based on sample size
grammatical and typo errors: please revise for grammatical and typo errors
figure title: revise figure 5,6,7 title for typo errors