Reviewer’s report
Title: 
Relationship between vitamin D receptor gene polymorphisms (BsmI,
TaqI, ApaI, and FokI) and calcium intake on bone mass in young Japanese
women
Version: 
0 
Date: 
15 Jan 2021
Reviewer: 
Longla Acheliu
Reviewer's report:
Generally, the main findings of the study have been presented concisely and
clearly making it easy to understand. The study also reveals important findings
on the association between genetic and dietary factors and bone mass among
young females in Japan. However, there were a couple of things that I will like
to highlight on the various sections of the manuscript. 
Abstract- Ok but a few issues that will be highlighted in the other sections
Introduction- OK
Methods- Please indicate the study design clearly
- No minimum sample size calculation
- Since the questionnaire used to assess calcium intake is not part of the article, I
think it is important to be a bit more explicit about about how the calcium intake
was assessed since quantitative measures of calcium intake were reported in your
study
Conclusion - You stated that your study could result in the development of
strategies to prevent loss of bone mass. I think you should mention one or two of
such strategies.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes