Reviewer ’s report  
 
Title: Lesion distribution characteristics of deep infiltrating endometriosis with ovarian  
endometrioma: An observational clinical study  
 
Version: 1 Date: 21 Mar 2020  
 
Reviewer: Pedro Acién  
 
Reviewer's report:  
 
However:  
- I do not agree with what they point out about the symptom dyspareunia: "There are no 
corresponding relationship between dyspareunia and DIE lesions in ligaments, vaginal, posterior 
fornix, etc. The presenc e of these lesions is often associated with dysmenorrhea". I believe that 
deep dyspareunia is the most specific symptom in women with DIE (if they have sexual 
intercourse) and corresponds to the pain induced by vaginal touch in the Douglas cul de sac and 
in the touch of nodules like pellets on the uterosacral ligaments.  
- You should review the bibliographic citations in the text: "Indeed, Maria et al. [11] created a 
predictive model…" "Diego Raimondo et al. [27] pointed…".  Maria is de name (M) "11. 
Perello , M., et al., Markers .. " and it should also be Raimondo D.  
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported  by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please spec ify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
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organisation that may in any way gain or lose financially from the publication of th is 
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3. Do you hold or are you currently applyi ng for any patents relating to the content of the  
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holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
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below.  If your reply is y es to any, please give details below.  
 
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