JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Intraoperative implantation of 125I seeds improves prognosis in refractory stage IIIB
cervical cancer: A Case Report and literature review
Version: 0 Date: 27 Nov 2023
Reviewer's report:
I read with great interest the manuscript, which falls within the aim of this Journal and offers
a high-quality overview of the topic.
The abstract perfectly summarizes the contents of the manuscript
Methodology is accurate and conclusions are supported by the data analysis. The figures are
clear and interesting.
Although the manuscript can be considered already of high quality, I would suggest taking into
account the following minor recommendations:
- I suggest another round of language revision, in order to correct a few typos and improve
readability.
- I find it interesting to include a reference to the screening programs for early cervical cancer
diagnosis (Golia D'Augè T, Giannini A, Bogani G, Di Dio C, Laganà AS, Di Donato V, Salerno
MG, Caserta D, Chiantera V, Vizza E, Muzii L, D’Oria O. Prevention, Screening, Treatment and
Follow-Up of Gynecological Cancers: State of Art and Future Perspectives. Clin. Exp. Obstet.
Gynecol. 2023, 50(8), 160. https://doi.org/10.31083/j.ceog5008160).
-What are the implications of these findings for clinical practice and/or further research?
-What are the strengths and limitations of this manuscript?
- I find it interesting to include a reference to the long-term outcomes of patients with cervical
cancer treated with a minimally-invasive approach compared to the "classic" open approach (see
PMID: 37149905).
Title: Intraoperative implantation of 125I seeds improves prognosis in refractory stage IIIB
cervical cancer: A Case Report and literature review
Version: 0 Date: 06 Dec 2023
Reviewer's report:
The authors present a case report on the use of radioactive seeds in the treament of a cervical
cancer patient. The idea of completing the therapy of patients with advanced lesion with
intratumoral radioactive seeds is definetely an interesting option and warrants further study.
However, the submitted manuscript requires further work in order to better  present the case
study. Firstly, the text requires English proofing in order to ensure a clear and fluent writting.
Secondly, the description of the case must be completed with more data, such as patient history
and co-morbidities (possible risk factors for the occurence of cervical cancer, HPV status, etc).
The timeline to each procedure should be more clearly outlined (how many weeks from diagnosis
to treatment initiation, from neoadjuvant radiotherapy to surgery). The authors mention that the
radioactive seeds were implanted in ”recurrent  tumors” - this is unclear, how could the patient
have recurring tumors if she was undergoing surgery for the first time? Abbreviations should
be defined at first use. The figures are not mentioned in text.  Since this procedure is not a
standard, the exact placement of the seeds following hysterectomy should be explained. Was
pelvic lymphadenectomy performed?
Title: Intraoperative implantation of 125I seeds improves prognosis in refractory stage IIIB
cervical cancer: A Case Report and literature review
Version: 2 Date: 03 Jan 2024
Reviewer's report:
The quality of the manuscript has improved thanks to the changes made. I think it could be of
interest to the readers and, in my opinion, it deserves the priority to be published.
Title: Intraoperative implantation of 125I seeds improves prognosis in refractory stage IIIB
cervical cancer: A Case Report and literature review
Version: 2 Date: 23 Jan 2024
Reviewer's report:
Thank you for the opportunity to review this interesting article. It is well written, although some
minor comments could be helpful and improve the quality of the article.
Line 23: m After undergoing radical hysterectomy and experiencing poor efficacy after
radiotherapy ... it is not celar what type of treatment was given first... radical hysterectomy or
radiotherapy? Please rephrase.
Line 58: Treatment options for recurrent or metastatic cervical cancer are limited and pose a
difficult and complex challenge... one of the safe and successful treatment options for recurrent
vulvar cancer is electrochemotherapy, which could also be used for cervical cancer. You could
mention this as part of the non-standardised treatment for recurrent cervical cancer in Vivod G,
Bosnjak M, Kovacevic N, Sersa G, Merlo S, Cemazar M. Safety and Feasibility of Vulvar Cancer
Treatment with Electrochemotherapy. Cancers (Basel). 2023;15(12):3079. Published 2023 Jun
7. doi:10.3390/cancers15123079
Line 81: The vulva showed normal development, indicating that the individual had been married
and had given birth ... i think normal vulvar development is not an indicator of marital status.
Marital status is also irrelevant to a research article. Rephrase the sentence or delete it.
Line 96: These lymph nodes were determined to be metastatic... on CT or PET-CT?
Line 171: Pelvic exenteration is a complex and demanding intervention, with a perioperative
mortality rate ranging from 2% to 5% and a surgical complication rate ranging from
32% to 84% [12]. These complications mainly include wound healing disorders, ileus
complaints, intra-abdominal abscesses or anastomotic insufficiencies, fistulas and ureteral
stenosis, resulting in prolonged hospital stays and poor quality of life after surgery.
Furthermore, some patients still face the risk of recurrence [13].... Perhaps mention
electrochemotherapy as an alternative to pelvic exenteration in Vivod G, Kovacevic N,
#emažar M, et al. Electrochemotherapy as an Alternative Treatment Option to Pelvic
Exenteration for Recurrent Vulvar Cancer of the Perineum Region. Technol Cancer Res Treat.
2022;21:15330338221116489. doi:10.1177/15330338221116489
Title: COVID 19 vaccination as a trigger of acute genital ulcers in an immunocompromised
adolescent - case study and literature review.
Version: 0 Date: 15 Oct 2023
Reviewer:  Dina Akeel Salman
Reviewer's report:
The comment
1. In line 26 add the full name of SARS-CoV-2
2.  In line   32   the paragraph so long is divided it into the paragraph
3.  In line   42 add the definition of acute ulcer.
4.  In line 68 add   Add abbreviation  CRP
5. In line 82 rewrite this part
6. In line 84 Table 1 specifies this normal range for females
7. In line 98 in Figure 2    is this picture placed after taken permission or not if your answer
is yes add it .
8. In line 115 add the most common cause of ulcers at this age
9. In line 159 Rewrite this paragraph
10.  In line 178 add the duration of follow up
11. In line 221 put a new reference
12. In line 307 unclear rewrite it
Title: COVID 19 vaccination as a trigger of acute genital ulcers in an immunocompromised
adolescent - case study and literature review.
Version: 0 Date: 15 Oct 2023
Reviewer's report:
It is an interesting case report about acute genital ulcers in an adolescent with a prior history of.
PFAPA syndrome and IgA vasculitis, which developed a week after  COVID-19 vaccination
(Comirnaty Pfizer BioNTech). The authors also discussed other causes of genital ulcers, such
as Behcet’s disease, infections, and malignancy. However, in the abstract (lines 31-33) they
highlighted only autoimmunity and COVID-19 vaccination.
"Review of literature is focused on the possible causal link between appearance of AGU,
autoimmunity, and COVID-19 vaccination".
1. Please add in this sentence other causes of genital ulcers you have discussed and add "the"
before "appearance".
2. The title "COVID 19 vaccination as a trigger of acute genital ulcers in an autoimmune
predisposed adolescent - a case report and literature review". PFAPA syndrome refers to
autoinflammatory, not an autoimmune syndrome, so would be better to write "in predisposed
adolescent" or " in immunocompromised adolescent".
3. There are many mistakes in the text that should be corrected. They are mainly related to the
omission of "the", "a" and commas. However, there are others.
4. Line 67. "dysuria from few days".  Please correct "dysuria for a few days".
5. Lines 131-132. inflamamtory cytokine IL-12, which stimulates CD4 and CD8 lymphocytes to
produce excessive amounts of IFN-# and lipopolisacharide (LPS). Please correct inflammatory
and lipopolysaccharides.
6. Lines 159-160. "We considered the possible influence of PFAPA syndrome on the
development of labia ulceration in our patient". In this case, as in the text in general, it is
necessary to correct that it was not the PFAPA syndrome that influenced the development of
ulcers, but the immune and genetic determinants that caused the PFAPA syndrome could also
lead to the appearance of ulcers after provoking factors.
Title: COVID 19 vaccination as a trigger of acute genital ulcers in an immunocompromised
adolescent - case study and literature review.
Version: 2 Date: 05 Nov 2023
Reviewer's report:
Despite many corrections being made, there are still many grammatical mistakes remaining.
Line 28. 12-years-old  should be 12-year-old.
Line 29 - history. Please add "a" before history.
Line 59 - ulceration,6., 7. Which is included in Figure 1.  Please correct  - which.
Line 166. According Scattoni et al.   Please add "to"  after according.
Line 191. Despite a different approach, the ulcers are usually self-limiting and heals... Please
correct "heal " instead "heals".
Line  206. "particular autoantibodies production ". Please correct  "particular autoantibody
production".
Line 212. "mucosal and skin lesion". Please correct "skin lesions".
There are other mistakes, mainly commas, and articles, so the text requires another proofreading
by a native speaker.
Title: COVID 19 vaccination as a trigger of acute genital ulcers in an immunocompromised
adolescent - case study and literature review.
Version: 2 Date: 18 Nov 2023
Reviewer's report:
The manuscript “COVID 19 vaccination as a trigger of acute genital ulcers in
immunocompromised adolescent - a case report and literature review” treats a very interesting
and useful topic. However, some minor changes are needed.
ABSTRACT: In the sentence “Infectious, autoimmune, malignant, traumatic, or vaccines are
the possible conditions” the author should specify “possible conditions associated with AGU”.
Also the acronym “COVID-19” should be firstly named entirely.
In the sentence “syndrome and IgA vasculitis (also known as Henoch-Schönlein purpura) in the
past” authors should write “in her past medical history”.
MANUSCRIPT
Line 46: “where a few ulcers”, authors should eliminate “a”.
Line 53: “flu-like symptoms might also occur. It is manifested..” authors should use the plural
since they are talking about flu-like symptomS.
Line 47 and 55: “An infection mainly triggers the conditions, which tend to resolve
spontaneously”,It is perceived that the etiology is viral.”, authors should said that the condition
tends to resolve spontaneously but should eliminate the other information since it is explained
in the next paragraph about the infectious etiology. There is the same information reported three
times in different ways.
Line 59: “Which is included in Figure 1” should be “which are included in Figure 1”.
Line 301: “are a heterogeneous” should be “are an heterogeneous”.
A "method section" should be included in the manuscript.
Title: Women’s access to sexual and reproductive health services and information in Ismailia,
Egypt
Version: 1 Date: 13 Jan 2023
Reviewer's report:
The overall impression of the work is good. The study is unique in its observation. The
manuscript is written in different sections. The method section of the study is well explained.
There are however some areas that need to be looked into. The manuscript could be improved
if the thematic area were further reviewed and refined and if findings were provided more
concisely. Moreover, there are some grammatical issues that can be rectified.
Major Issues
• Abstract: Please review the thematic area in the result section and provide information based
on your findings. Furthermore, the study has explored neither the quality of SRH services nor
the relations and collaboration between the government and relevant stakeholders. It would be
better to provide recommendations based on the study's findings.
• Introduction: The content of the introduction section need to be reviewed and revised. It would
be better to start with the definition of SRH, link SRH with SDG, and write about the global,
regional and national level initiatives (including SRH service provided in the study area).
• Method: Information related to interview guidelines, major changes made after the pilot study,
interviewer qualification, and determination of saturation level were missing in the manuscript.
• Result: Please review and refine the thematic area. Results are not presented as mentioned
in the last paragram of page no 10  of the manuscript  [(4) The facilitating factors that make
it easy for women to access SRH services and information, (5) The challenges that make it
difficult for women to access SRH services and information, (6) Married women’s suggestions
for improving their access to SRH services and information to ensure their sexual health and
sexual wellbeing, were missing]
• Discussion: Need to rephrase the discussion session making it more concise and informative.
• Conclusion: The study has explored neither the relations and collaboration between
government and relevant stakeholders nor the gap in the national policies and political
commitment. It would be better to provide recommendations based on the study's findings.
Minor Issues
1. There exist some typing errors and grammatical mistakes, that need to be corrected.
Title: Women’s access to sexual and reproductive health services and information in Ismailia,
Egypt
Version: 1 Date: 25 Jan 2023
Reviewer:  Vitalis Ngambouk
Reviewer's report:
This manuscript examines a very pertinent reproductive health issue---women's access to sexual
and reproductive health services in  Ismailia, Egypt. The choice of Ismaila is not justified, neither
do we know the population.
There is, however, engagement with the literature on the topic, with comparisons to other Arab
countries. It is sufficient  for publication as it stands.
Title: Women’s access to sexual and reproductive health services and information in Ismailia,
Egypt
Version: 2 Date: 09 Aug 2023
Reviewer's report:
Brief Summary of the Manuscript
The overall impression of the work is good. The author has integrated most of the inputs
provided.
Details comments on the paper
Major Issues
• Abstract: Please provide the specific findings of the study regarding the factors affecting
women's access to sexual and reproductive health (SRH) services and information. It's important
to note that the policy factor was not mentioned in the results section.
• Result: It would be better to focus on developing a theme and sub-theme that emphasize the
intersectional factors affecting women's access to SRH services and information.
• Conclusion: Please state the specific findings of the study regarding the factors affecting
women’s access to SRH services and information. Please include any novel insights uncovered
by your study in the conclusion section
Minor Issues
• Method: Please mention the type of health professional [within brackets].
• There still exists some typo errors and grammatical mistakes, that need to be corrected
I have thoroughly gone through the manuscript. There are no ethical concerns and I couldn't
find any conflict of interest, plagiarism or violation of the publication ethics. This study can be
published with a few revisions.
Title: The role of a community health worker-delivered preconception and pregnancy
intervention in achieving a more positive pregnancy experience: the Bukhali trial in Soweto,
South Africa
Version: 1 Date: 18 Nov 2023
Reviewer's report:
Comments:
Thank you for your important work on pregnancy experiences in South Africa! It was a pleasure
to read this manuscript. Thank you for advancing this important work.
Minor comments:
1. Methods indicate 15 IDIs were conducted, but one participant is referred to as IDI 16 (page
15). Is this a typo? If not, please clarify the numbering.
2. I noted inconsistent use of acronyms. Be sure that all acronyms are spelled out at first use
(BMI, BP on page 13; health helpers/HH throughout and in Table 2). I also recommend adding
these acronyms to the list on page 22.
3. Table 2 – there are two boxes with the symbol “/” – please define or provide more information.
Are these not applicable based on the design of the intervention?
4. Page 16 – typo in quote on the second line of the page should be “you’re”
5. Page 16 – illustrative quote clarification for third quote. “It was less when I spoke to people…”
Please add clarification – what is the participant referring to?
Major comments:
1. I recommend including a COREQ checklist as an appendix, ensuring that methods are reported
comprehensively and sufficiently to allow the study to be repeated. Many, but not all, of the
items on the COREQ checklist are reported in the manuscript.
2. The results and discussion would be strengthened by presenting and analyzing disconfirming
evidence. For example, section 3.1.1 suggests all participants were unhappy about being
pregnant, yet one of the quotes describes initial disappointment followed by feelings of
happiness. I recommend adding nuance to the write-up, exploring mixed feelings that
participants described. I have similar comments for subsequent sections – for 3.1.2, did any
participants describe feeling that motherhood would be easier as it was their second baby, or that
responsibilities would be easier to manage? For 3.1.3, did any describe an easier pregnancy?
For 3.1.4, the theme suggests lessened social support and traumatic experiences, but some
participants described increased support with the second pregnancy (second illustrative quote)
– I recommend adding nuance to the text describing these findings.
3. The discussion clearly describes was in which the results support the three equal and
complementary pillars of care. Where are there areas where participant experiences did not
cleanly support these pillars of care? Did any participants describe other areas as important to
their experience, not covered by these three domains? I recommend deepening this analysis to
provide more complex insights based on participant interviews.
Thank you again for this important contribution!
Title: The role of a community health worker-delivered preconception and pregnancy
intervention in achieving a more positive pregnancy experience: the Bukhali trial in Soweto,
South Africa
Version: 1 Date: 30 Nov 2023
Reviewer's report:
• In the abstract part under method section narration is needed
o Include pertinent parts of the research part like statical analysis, data collection method,
sampling method , sample size n other  you mentioned issues not a such impressive for scientific
community (readers)
o The result should be mentioned as a theme to make it inclusive
o The conclusion should include PCC
• Under method part
o Say methods and materials
o Study design, setting, and population
# Although the socioeconomic milieu is increasingly varied, young women living in Soweto
are faced with several structural and social challenges. These include experiencing traumatic
events, gender-based violence, unemployment, food insecurity, mental health challenges, and
limited health literacy [21–27]. Rather than this issue it is better to write description of your study
population which in lines with your study objective…..take it the above sentence in introduction
part it is unnecessary here
#  All reproductive age group women are eligible for your study why you only included18-28
aged women
# In analysis – mention the software used
o In result part--- only write results avoid unnecessary descriptions
# Start with result of the study based on your objective by giving heading like characteristics of
the study,…then describing the mentioned issues
# Also before the figure narration about the figure is needed
# …3.2 Trial components influencing pregnancy experiences
# Table 2 provides an overview of the identified ways in which intervention support, information,
and care practices influenced participant experiences in pregnancy, which are described in more
detail in sections 3.2.1-3.2.3. These identified processes can be categorised into four main
themes, namely “acceptance and mother/child bonding”, “growing and adapting in their role as
a mother”, “receiving tools for their health”, and “having ways to cope in difficult situations”.
Lastly, Table 3 summarises the identified gaps in routine ANC care for support, information,
and care practices…… this is not informative first narrate about table two and cite it
o Discussion part
# The first paragraph seems summery ----avoid it replace with evidences related to your objective
Title: Presentation and treatment of two cases of malignant struma ovarii
Version: 2 Date: 13 Jan 2024
Reviewer:  Imane Boujguenna
Reviewer's report:
A very interesting article that adds scientific value to the literature.
Reported cases of struma ovarii are rare, even more so if it is a malignant variant.
my comments are of interest:
Images: I suggest you add macroscopic and radiological images.
Anatomopathological examination: specify the criteria that led to the diagnosis of papillary
carcinoma and that classify well-differentiated high-grade thyroid carcinomas: mitotic index and
necrosis, essentially according to the latest WHO classification.
BRAF in papillary thyroid carcinoma of ovary (struma ovarii).
Jason Schmidt 1, Victoria Derr, Michael C Heinrich, Christopher P Crum, Jonathan A Fletcher,
Christopher L Corless, Vânia Nosé.
References: add to references: WHO classifications.
I congratulate you once again on the quality of your article.
Title: Presentation and treatment of two cases of malignant struma ovarii
Version: 2 Date: 19 Jan 2024
Reviewer's report:
I would like to thank you for inviting me to review this manuscript. I read the article carefully but
didn't find the novelty in the subject of the research and the obtained results. Another concern is
about the structure of the article. Considering the CARE checklist is essential for reporting a case
report. Besides, in the discussion section, it is unclear how your added research will dispel many
of the misunderstandings surrounding this difficult situation since the data was only described
and you did not contribute significantly to better manage these problems.
Title: Presentation and treatment of two cases of malignant struma ovarii
Version: 2 Date: 20 Jan 2024
Reviewer's report:
Authors introduce the explore the dearth of consensus on optimal management of the condition
in their introduction before presenting the 2 cases of malignant stroma ovarii (MSO) managed
in their facility.
They present their management and present literature that supports their management choices
while presenting fertility sparing options available in carefully selected patients.
Well written case reports