Reviewer’s report  
 
Title:  Laparoscopic sacrocolpopexy versus vaginal sacrospinous fixation for vaginal vault 
prolapse, a randomized controlled trial: SALTO -2 trial, study protocol  
 
Version:  0 Date:  02 Feb 2017 
 
Reviewer:  Patrick  Dällenbac h 
 
Reviewer’s report:  
 
This is a very interesting research protocol.  
 
My only comment is about sutures used in your protocol.  For sacrospinofixation, I don't think it 
is necessary to use non -absorbable sutures. Vicryl sutures work just as well as it is the fibrosis 
who will do the job. I am happy that you use PDS, an absorbable suture, to fix the mesh in the 
sacrocolpopexy group, the principle of fibrosis fixing the mesh is the same. However, PD S is a 
long lasting absorbable suture and I am not sure that it is necessary, as the mesh will be 
colonized during the first two weeks allready. Moreover, PDS is a monfilament, which is more 
difficult to use it laparoscopically than Vicryl.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Unable to assess  
 
Are you able to ass ess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I recommend additional statistical review  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
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