Reviewer’s report
Title: 
Lifestyle modifications after the diagnosis of gynecological cancer
Version: 
2 
Date: 
26 Nov 2020
Reviewer's report:
I read with great interest the Manuscript titled "Lifestyle modifications after the
diagnosis of gynecological cancer" (BMWH-D-20-01066R2), which falls within
the aim of BMC Women's Health. 
In my honest opinion, the topic is interesting enough to attract the readers'
attention. Methodology is accurate and conclusions are supported by the data
analysis. Nevertheless, authors should clarify some point and improve the
discussion citing relevant and novel key articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be further revised by a native English speaker.
- Inclusion/exclusion criteria should be better clarified.
- The Authors did not mention the sample size calculation for their study. It is
essential to specify this data in order to guarantee an adequate significance of the
results obtained by the Authors.
- In the Results section, the Authors have simply reported the p values from
which however it is not possible to deduce the real clinical relevance of the
highlighted statistical significance. In order to better understand the results
obtained, I strongly suggest reporting not only the p values but also the
corresponding confidence intervals.
- The authors have not adequately highlighted the strengths and limitations of
their study. I suggest better specifying these points.
- What are the actual clinical implications of this study? it is important to report
the results obtained by the authors in the context of clinical practice and to
adequately highlight what contribution this study adds to the literature already
existing on the topic and to future study perspectives.
- It would be interesting to underline the impact of lifestyle modifications on
other female conditions such as reproductive health and pregnancy. I suggest
referring to these recent articles on the topic: PMID: 30994167; PMID:
30501641.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes