Reviewer’s report
Title: 
Clinical and MRI features of sacral insufficiency fractures after
radiotherapy in patients with cervical cancer
Version: 
1 
Date: 
20 Aug 2021
Reviewer: 
Gordana Kovacevic
Reviewer's report:
The authors report that SIF is a common complication in cervical cancer after
radiotherapy and 
coronal FS-T2WI, probably more useful for detection of these fractures than
other imaging 
sequences. The manuscript is concise, well written and provides important data.
All sections are 
well-structured and sufficient in size.
I have few minor suggestions in section Method
1. I suggest to authors to better define a Reference Standard which they used in
the study 
2. Please ensure acceptable statistical method which would support your
conclusion that
coronal FS-T2WI is more useful for detection and characterization of fractures
than other 
imaging sequences.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
No
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes