Reviewer’s report
Title:  Cyprus Women’s Health Research (COHERE) Initiative: Determining the relative burden of
women’s health conditions and related co-morbidities in an Eastern Mediterranean population
Version: 0 Date: 21 Feb 2019
Reviewer: Omero Bendicto Poli-Neto
Reviewer's report:
The manuscript presented describes a project that is currently recruiting participants.
It aims to identify the prevalence of benign gynecological conditions in the population of women living
in Northern Cyprus, predominantly of reproductive age, as well as to verify possible correlations
between phenotype and genetic characteristics and exposure to environmental factors.
The justification of the study is adequate, the hypotheses are plausible, and the method presented is
detailed and reproducible. The creation of a sample biobank has the potential to integrate with local,
regional and international women's health research groups. The calculation of the power of the test is
adequate, as well as the forecast of statistical analysis. Predicting security and compliance in the
database is also a plus.
The only item I miss and I suggest to the authors is the possibility of investigating the prevalence of
violence against women, physical and sexual.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further
assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
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