Reviewer’ s report
Title: Efficacy and cardiovascular safety of the new estrogen-free contraceptive pill containing 4
mg drospirenone alone in a 24/4 regime.
Version: 2Date: 07 Sep 2020
Reviewer: Onur Erol
Reviewer's report:
I read with great interest the manuscript titled as 'efficacy and cardiovascular safety of the new
estrogen-free contraceptive pill containing 4 mg drospirenone alone in a 24/4 regime'.Overall the manuscript is well written and the study participants are well described.In the revised form of manuscript, authors completely responded to comments.
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Creative Commons CC-BY License (http://creativecommons.org/licenses/by/4.0) if this manu-script is accepted for publication. Any comments that I do not wish to be included in the publishedreport have been included as confidential comments to the editor, which will not be published.Ifyou are not happy for us to publish this report, please contact the editorial office before completingthe review.If you wish, you can include your name in your published report. Please note you mustdecide whether to include your name at the start of the process and confirm this decision wheneverprompted. If you change your decision later, we will not be able to publish your name.
I agree to the terms of the CC-BY 4.0 license; please publish my name with my report.Is the study design appropriate to answer the research question (including the use of appropriate
controls), and are the conclusions supported by the evidence presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
YesIs the use of statistics and treatment of uncertainties appropriate?YesIs the presentation of the work clear?YesAre the images in this manuscript (including electrophoretic gels and blots) free from apparent
manipulation?
Yes