Reviewer ’s report  
 
Title: Risk factors and a prediction model for lower limb lymphedema following 
lymphadenectomy  in gynecologic cancer: a hospital -based retrospective cohort study  
 
Version: 0 Date: 15 Mar 2017  
 
Reviewer: Soo-Young Hur  
 
Reviewer's report:  
 
1.This article included carcinoma of cervix, endometrium, ovary, vagina and tube. The 
characteristics of disease are very different from each other.  
 
 
Especially cervix, vagina vs ovary, tube.  
 
 
So it needs to be classified  and analyzed the risk factors according to disease seperately(Also HR 
and cumulative incidence...).  
 
 
Authors need to make a prediction model according to disease.  
 
 
 
2. Authors need to remove all unnecessary vertical lines and horizontal lines from all table s. 
 
 
3. Authors must describe the method to rull out DVT, Which one did you use? CT, D -dimer, or 
duplex sono ?  
 
 
4. Describe the method to diagnose lymphedema - thickness of thigh, knee, ankle/ differences of 
thickness between both legs  
 
 
5. describe the underlying disease of patients such as congestive hear failure, nephrotic 
syndrome, prior DVT history or other medical disease in table 1.  
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments t o the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review ? 
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I recommend additional statistical review  
 
Quality of written English  
Please indicate the quality of language in the manus cript:  
 
Acceptable  
 
Declaration of competing interests  
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