JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Investigating genetic links between blood metabolites and preeclampsia
Version: 4 Date: 30 Jan 2024
Reviewer's report:
Dear respected Authors,
I appreciate the comprehensive revisions made to the article titled "Investigating Genetic Links
Between Blood Metabolites and Preeclampsia." Your detailed response to reviewer comments
and the adjustments made in the manuscript have significantly strengthened the overall quality
and clarity of the study.
The refined study design, methods, and results sections have greatly improved the readability
and accessibility of your research. The additional details on sensitivity analyses, validation with
an independent dataset, and the pathway analysis contribute to a more robust and well-supported
study.
The revised abstract now succinctly encapsulates the key aspects of your study, providing a clear
and concise overview of the research objectives, methods, and primary results. The introduction
effectively contextualizes the research question within existing literature, and the inclusion of
keywords enhances the article's indexability.
In the results section, the balanced presentation of primary and validation analyses facilitates
a coherent interpretation of the identified metabolites associated with preeclampsia. The
conclusions appropriately convey caution, acknowledging the limitations of Mendelian
randomization studies and emphasizing the need for further research to confirm causality and
elucidate underlying mechanisms.
Given the diligent response to reviewer feedback and the improvements made to the manuscript,
I recommend the acceptance of your revised submission for publication. Any minor adjustments
suggested by the editorial team can be addressed in the final stages of the publication process.
Thank you for your meticulous efforts in enhancing the manuscript. I look forward to the
dissemination of your valuable contributions to the field.
Sincerely,
Title: Investigating genetic links between blood metabolites and preeclampsia
Version: 4 Date: 06 Feb 2024
Reviewer:  Hussein Wahhab Saleh Rabeea
Reviewer's report:
Dear editor, I would like to thank you for your trust in allowing me to revise this article.
the researcher completed the necessary modifications to this  paper,
I have completed my review of your manuscript and would like to commend you on your effort
and dedication to this research topic.
Title: Reproductive factors and risk of cardiovascular diseases and all-cause and cardiovascular
mortality in American women: NHANES 2003-2018
Version: 2 Date: 22 Oct 2023
Reviewer's report:
Dear author’s
I was plesed to review your article and I have the following comment’s:
First of all the sample of your study is relevant.
I recommend you to make more clear the reproductive factors to draw a picture in order to
highlight this factors.
It is not clear how this information was obtained (medical records or patient survey?)
Please explain the limitations of your study.
How you propose to assess this factors in current practice?
Title: How Men Influence Young Women Taking PrEP: Perspectives from Young Women,
Male Partners, and Male Peers in Siaya County, Western Kenya
Version: 0 Date: 05 Jan 2024
Reviewer's report:
I congratulate the authors on an excellent study that used photovoice to capture multi-level
barriers to young women's PrEP use in Kenya. The use of photovoice was fantastic and yielded
some really important insights that otherwise might not have emerged from in-depth interviews
or focus group discussions alone. I had mostly minor comments for the authors, specifically
related to the study methods and discussion:
Abstract:
-Line 28: Replace "persistently" with "consistently".
-Line 38: Rather than a "negative" male influence, perhaps consider shifting the language
towards "constraining", so it doesn't inadvertently imply malicious intent by males.
Introduction:
-Line 89: Replace "prostitution" with "sex work".
-It would be helpful for the authors to articulate specific research gaps with respect to the
influence of men on young women's PrEP use, if anything to provide a stronger rationale for
the work in the introduction.
Methods:
-Pg. 7: The audience may not be familiar with the DREAMS program. I would add 2-3 sentences
to describe DREAMS programming and implementation in Africa and Kenya.
-Pg. 7: More details on study recruitment would be helpful. How were individuals specifically
identified through DREAMS (e.g., registers)? How were men identified and approached for
participation? Who was responsible for recruiting individuals and enrolling them into the study?
-Pg. 8: It would be helpful to articulate the dates of data collection or timeline of study activities.
-Were participants provided any photography training or given equipment to complete the photo
assignments?
-How were issues of confidentiality and privacy handled, especially in contexts where
participating young women and men might have known one another?
Results:
-In Table 1, it appears that the age range for one of the groups was 10-24. I assume this is a
mistake? Should this be 18-24? It also appears that the remaining groups had individuals aged
20 and older. If that is the case, I would rephrase the expression young women throughout the
manuscript to clarify that individuals under 20 years-old were not included in the study.
-Line 247: As above, it's important to rephrase "negative male influence" to "constraining male
influence" or something similar.
Discussion:
-The first sentence of the discussion should open with a takeaway message related to PrEP,
rather than the "limited autonomy" women have over their sex lives, which to me didn't feel like
the take-home message of the results.
-There are three large elements missing from the discussion: a synthesis of how these findings
explain the status of PrEP rollout/scale-up in Kenya at the time of study; what these study
findings offer in terms of opportunities to adapt PrEP implementation strategies in Kenya; and
limitations of the study.
Title: How Men Influence Young Women Taking PrEP: Perspectives from Young Women,
Male Partners, and Male Peers in Siaya County, Western Kenya
Version: 0 Date: 19 Jan 2024
Reviewer's report:
The authors submitted an impactful paper describing the impact men have on young women’s
PrEP use in Western Kenya. I read the paper in detail and only have minor comments below.
Line 31: Recommend indicating that YW who had previously taken (or discontinued) PrEP were
also included based on the study eligibility criteria.
Table 1: It is recommended to indicate PrEP use status by the young women, indicating those
currently or previously on PrEP.
Figure 6: This picture is dated in 2016, which was prior to the study in 2019. Additional context
is needed since this photo was not taken as part of the photovoice project.
Title: A mixed methods systematic literature review of barriers and facilitators to help-seeking
among women with stigmatised pelvic health symptoms
Version: 0 Date: 07 Mar 2024
Reviewer's report:
This was a very well-written and interesting manuscript on an important and timely topic. The
authors provided thorough detail on how they conducted the systematic review and their use of
theory to help explain their findings strengthened the paper. I only have minor feedback:
Background:
Line 97: The sentence starting “Stigma surrounding...” is confusing to read- it could be broken
into two sentences or reworked to remove one of the commas. A small typo also needs to be
fixed- add the letter ‘s’ to “because it stop”.
Methods:
Line 183: Please add whether the search conducted in MEDLINE was similar to searches
conducted in other databases.
Line 206: I appreciate you including a section on researcher reflexivity. In line with this, you
could include who or the number of researchers involved in data analysis at each stage.
Line 207: The term ‘narrative synthesis’ may be more appropriate here instead of narrative
analysis (a specific type of qualitative data analysis).
Line 220: Unless I missed it, the data richness scale was used but it is not mentioned again in
the paper or the quality assessment section. Should the outcomes from this be included?
Results:
Table 5: Include a note at the bottom of the table to clarify what is meant by “blog posts” - does
each blog post represent a different woman?
Line 303: The section starting “Primary qualitative data” may better belong in the data analysis
and synthesis section to expand on how you conducted the reflective thematic analysis.
Line 304: The term “from quantitative data analysis is used” is a bit confusing- it may be clearer
to use the term “analysis of quantitative data” or “quantitative content analysis”?
Outcomes:
Table 6: While ‘Unclear candidacy’ is discussed and explained in the following section, it may
be helpful for the reader to make this more descriptive- i.e. unclear candidacy for help seeking
or to add a reference .
Title: Perimenopausal syndrome and hypertension during perimenopause in South China:
Prevalence, relationships and risk factors
Version: 3 Date: 01 May 2023
Reviewer's report:
It is necessary to check the entire data. Regarding the prevalence, it would be easier to understand
if there were visual data.
page 2. line 21-22: duplication of expression: The prevalence of hypertension in perimenopause
is 16.58%, and the prevalence of hypertension in perimenopause is 16.58%.
page 4. line 35 : sprior
page 5. line 107: Men's standard of abdominal overweight does not need to be stated.
page 6. line 129: typo. The prevalence and of HTN in perimenopause is 16.58%.
page 9. line 140: Is it right? The prevalence of perimenopausal syndrome in the different age
groups are 18.2%, 22.4%, 27.6%, and 31.8%
-> According to the table, it seems that it is not the prevalence rate by age group but the ratio of
the number of persons in that age group to the total prevalence population.
Table 2. In Table 2, the severity of perimenopausal syndrome was not indicated. Therefore, it
seems necessary to correct the title.
Table 4: Full names for abbreviations such as WC and BMI are required at the bottom of the
table.
Title: Perimenopausal syndrome and hypertension during perimenopause in South China:
Prevalence, relationships and risk factors
Version: 3 Date: 27 Dec 2023
Reviewer's report:
Your article is interesting and valuable/ but it is confusing for the reader due to the large amount
of content/ the text of the article should be corrected clearly
Abstract:
Page 2 line 21: The first two sentences results are repeated
What was the prevalence of perimenopausal syndrome?
Lines 25-30 Lines 25 to 30 should be checked for grammar
The predictors of each outcome should be mentioned separately  with numbers.
Introduction:
What is your gap knowledge?
Methods:
Page 4 line line 79: what is your mean (unrelated)? “A total of 3553 subjects (40~60 years)
who were unrelated and sufficient to complete the questionnaire were included in the current
analysis”
What was your inclusion criteria?
Lines 100-103: what is your mean about standard protocol?
Write the reference for normal range
What is your study design?  Cross sectional or case-control?
You used modified Kupperman index (mKMI)? Is this index valid and reliable?
Do not explain the case and control well? It is very vague  in text and table
Results:
In general, you have not written the results in a basic and clear way/ avoid repeating the contents
in the text and table
Lines 140-141 mentioned age groups
The results are too broad and confusing/ the results should be written more clearly and concisely
for better understanding
Title: Perimenopausal syndrome and hypertension during perimenopause in South China:
Prevalence, relationships and risk factors
Version: 5 Date: 01 Feb 2024
Reviewer's report:
Most of the points pointed out have been corrected well, but some additional corrections are
needed.
1. For abbreviations in all tables, please add the full name as a footnote. Additionally,
abbreviations should be unified. In Tables 2 and 3, two abbreviations, mKMI and mKI, are used
for the modified Kupperman index.
2. line248. There is no mention of income in the text. Please add evidence for high-income.
Title: Successful management of VTE with essential thrombocythemia and cavernous
transformation of the portal vein in early pregnancy: A case report.
Version: 1 Date: 15 Feb 2024
Reviewer:  Nora Sabah Rasoul
Reviewer's report:
Dr. Nora Sabah Rasoul
Dear authors
I read with great interest the manuscript, it is an interesting case that may provide a help in risk
assessment of pregnant women with essential thrombocythemia.
I have several notes hope to be taken in consideration.
1. Title: I suggest to be “Successful management of early pregnancy VTE with essential
thrombocythemia and cavernous transformation of portal vein.  A case report.
2. The abstract should contain no abbreviations.
3. Re-write the abstract to include the important information regarding case description for
example (thrombocytopenia).
4. The word anticoagulation is not appropriate in many sentences it should be replaced by
anticoagulant.
Case presentation
1. Please mention that the patient had no history of miscarriage.
2. Add more details about examination after DVT and mention if it is unilateral or bilateral.
3. Please mention in which vein DVT occur.
4. Line 76 please change” with the gestation age” to “with 12 weeks gestational age”.
5. Line 78 please change vaginal heamorrhage to vaginal bleeding.
6. Line 81 which investigations you mean regarding serum chemistry?
7. Line 87 “abnormalities of the abnormal abdominal ultrasonography” please delete “the
abnormal”.
8. Line 93 is it node or nodes?
9. The description should be below the figures.
10. Fig. 1 (the diagnostic of ultrasonography……) please re-write this sentence
11. The discussion part needs more description.
12. Add an abbreviation list please.
Title: Successful management of VTE with essential thrombocythemia and cavernous
transformation of the portal vein in early pregnancy: A case report.
Version: 1 Date: 21 Feb 2024
Reviewer:  Susan Abed Zaidan
Reviewer's report:
A case of treatment of thromboembolism in pregnant woman with thrombophilic disorder is not
a rare case regardless the cause and not enough to be a case report.
In addition, there is confusing information. At (History of Hematological diseases) , the platelet
count was 263 × 109/L  and when presented with leg pain and platelet count was 109 × 109/
L i.e. normal platelet count while the author mention in the discussion an unexpected elevated
PLT count (800 × 109/L) during the regular check-ups. In addition, in the discussion , (The
unexpected elevated PLT count (800 × 109/L) during the regular check-ups caught the patient’s
attention and led her to seek further professional evaluation ), well, the evaluation as written in
the (case presentation) and (History of Hematological diseases) were done only when patient
present with leg and abdominal pain respectively and in both cases with normal platelet count.
Title: Successful management of VTE with essential thrombocythemia and cavernous
transformation of the portal vein in early pregnancy: A case report.
Version: 1 Date: 06 Mar 2024
Reviewer's report:
dear authors:
1. Title: should be changed to ( Successful management of early pregnancy  VTE with essential
thrombocythemia and cavernous transformation of the portal vein: A case report )
2. Keywords: Add words that identify  interventions in this case report, including "case report"
3. Abstract:
- What is unique about this case and what does it add to the scientific literature?
- Main symptoms and/or important clinical findings.
4. Case presentation
- the pain should be described and characterized.
-  complete medical history should be added.
- Add obstetric history
- regarding the following sentence (Emergency ultrasonography was quickly performed and it
revealed deep vein thrombosis formation in her left lower extremity). Did you mean a Doppler
study of the lower limbs?
- The medical history, clinical examination, and laboratory tests must be written sequentially.
- what were the indications for the following tests (hepatic and renal functions, thyroid function,
serum chemistries, and cardiac function)? What do mean by serum chemistries?
- from where the history of Hematological disease was obtained?
5. Therapeutic Intervention:
- Administration of the previous therapeutic intervention ( dosage, strength, duration)
6. Discussion:
- a new elevated platelets count is mentioned in the discussion, but no previous information
about this lab result. you need to consider this in the case presentation.
- what was the indication of (emergency laparoscopic myomectomy in the puerperium)?
why was not mentioned previously?
- remove the summary from the discussion.
7. update the references
9. A full grammar review is required.
Title: Determinants of household decision making autonomy among rural married women based
on Ethiopian Demography Health Survey: a multilevel analysis
Version: 0 Date: 15 Jan 2024
Reviewer's report:
Well done and please consider the following minor comments either by incorporating or
justifying them.
Review summary
Title
Determinants of household decision making autonomy among rural married women based on
Ethiopian Demography Health Survey: a multilevel analysis
Okay
Abstract
Introduction and method
Okay
Result
…68.55 % (CI: 67.5%, 69.5)…what is this and if it is prevalence, does it go with your objective?
Being autonomous versus non-autonomous…vague.
Under introduction, you stated “Therefore the main purpose of this research project is to
investigate the potential determinants of rural women’s household decision making autonomy“
versus result report…make it a bit clear.
Introduction
Good and please consider direction of concerned office/ministry from Ethiopia about the
direction on your study because they are major stakeholders for the implementation.
Method
Data collection took place over data collection took place over…avoid this redundancy
It was dichotomized as (autonomous=1 and not autonomous=0)…this indicates that the report
depends on being ‘autonomous’ and it has to be reported in the abstract result section too.
Under operational definition, you have to report how you measured ‘women’s autonomy’
including how you created composite score….did you get it from record as it is or you calculated
it depending items used to define and measure the outcome variable? If you got it as it is, how
did you trust it?
Result
You used 3 pages to report Table 1 and please report it in a single page by being very selective…
otherwise, it is boring.
From the total respondents, 68.55% (CI: 67.5%, 69.5 %) women’s decision making autonomy…
how you reached on this decision is not clear in the method section.
Discussion: Okay
Conclusion
Generally women’s decision making autonomy was high (68.55%)…what is your reference
when you said ‘high’?
Title: Determinants of household decision making autonomy among rural married women based
on Ethiopian Demography Health Survey: a multilevel analysis
Version: 0 Date: 19 Jan 2024
Reviewer's report:
Authors presented a topical research which was very well justified with robust methodology and
appropriate statistical analysis. Results  were presented in a coherent manner and discussions
on the research findings were thorough.I would however suggest that the authors discussion
the implications of the wide 95% Confidence intervals on their conclusions about the influence
of the individual and community level characteristics associated with women decision making
autonomy(WDMA).Examples are as follows:Who decides on marriage (parents: AOR 0.76;
95% CI; 0.67, 0.87), and proportion of early marriage in the community (high proportion of
early marriage AOR: 1.35; 95% CI; 1.10, 1.72) ,there are some pretty wide Confidence intervals
with these adjusted odds which indicate a level of uncertainty with the conclusions arrived at
from the study findings.These were not reflected in the discussion.This observation also applies
to Table 5 which illustrates the Individual and community level characteristics  associated with
WDMA in Ethiopia which were subsequently reflected in the final model AOR,THE 95% CI
for religion for example crossed 1 for adherents of Islam,Protestant Christians and others.This
was also the case for age at first sex across the different age ranges .
Title: Determinants of household decision making autonomy among rural married women based
on Ethiopian Demography Health Survey: a multilevel analysis
Version: 2 Date: 16 Mar 2024
Reviewer's report:
Dear authors
Please. These recommendations be revised or responded:
- In title:  The household decision making autonomy about??? (the use of healthcare services,
childbearing, Fertility, contraceptive use, or …?
- If the use of healthcare services: Women’s decision with regard to the use of healthcare
services may depend on not only their socio-economic position, but also perception towards
modern healthcare treatment, family size, perceived severity of illness, and previous experience
of illness, that you didn’t. therefor report in methods and limitation section.
- In the section introduction in abstract and full text: problem is household decision making
autonomy, Women’s autonomy, Empowering women, or Women’s decision?
- In the discussion section: This finding contradicted with other findings from Ethiopia. What
is your explain in this section? You didn’t explain it.
- In the discussion section: you explain or discus Discuss from the point of view of religions,
Insurance, media exposure as well.
Sincerely
Title: Abdominal obesity as assessed by anthropometric measures associates with urinary
incontinence in females: Findings from the National Health and Nutrition Examination Survey
2005-2018
Version: 0 Date: 14 Dec 2023
Reviewer's report:
Abstract
-The abstract should avoid vague phrases like “more severe degree” or “better ability” and
instead report exact estimates such as odds ratios, confidence intervals, and p-values.
Introduction
-Suggest adding epidemiological data on UI prevalence in the opening paragraph for context.
Include a discussion on biological or physiological mechanisms linking abdominal obesity to UI.
-Suggest doing a more detailed review of existing literature to articulate the study's gap, focusing
on anthropometric indices and UI.
-Clearly state the study aim, its importance, and uniqueness. Suggested phrasing: "In this
study, we aim to examine.... and to compare their predictive value with other commonly used
anthropometric measures, such as BMI and WC. To our knowledge, this is the first study to
explore the relationship between these novel anthropometric indices and UI in a nationwide
prospective cohort."
Methods
-The present analysis used DXA data sets released by NHANES on the CDC website, where
missing data were not completely random (https://wwwn.cdc.gov/nchs/nhanes/dxa/dxa.aspx).
Multiple imputation was used at the National Center for Health Statistics as described in
the technical documentation available on the aforementioned website (https://wwwn.cdc.gov/
nchs/data/nhanes/dxa/dxa_techdoc.pdf). SAS SUDAAN 11.0 should be used to account for the
complex survey design and a multiple-imputed data set to reduce bias.
Results
-The analysis should be redone to confirm the consistency of the results.