Reviewer’s report  
 
Title: Vaginal Leiomyoma: Medical Imaging and Diagnosis in a Resource Low Tertiary 
Hospital: Case Report  
 
Version: 1 Date: 11 Oct 2019  
 
Revi ewer: Jo Kitawaki  
 
Reviewer's report:  
The authors reported a case of vaginal leiomyoma treated with laparoscopic and transvaginal 
surgery. They presented the difficulty to diagnose a vaginal leiomyoma preoperatively by MRI. 
They concluded that pathological diagnosis during surgery should be performed in the cases of 
vaginal tumors.  
Overall, the authors revised the manuscript appropriately in accordance to the reviewer's 
suggestions. However, there are still some points to be revised.  
 
1) The authors should state the main data of routine laboratory tests. Especially, lactate 
dehydrogenase (LDH) is important to exclude leiomyosarcoma.  
2) In the conclusion section, the authors stated that routine frozen s ection biopsy is needed in the 
diagnosis of vaginal tumors. The authors should add some discussion about pathological 
diagnosis during surgery to meet the conclusion.  
3) There are still typographical errors in the main text and figure legends. The manuscr ipt should 
be checked carefully.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manu script:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, f unding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially fr om the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization t hat 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have  no co mpeting interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
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