Reviewer ’s report  
 
Title:  Difference in vaginal microecology, local immunity and HPV infection among 
childbearing -age women with different degrees of cervical lesions in Inner Mongolia  
 
Version: 0 Date: 15 May 2019 
 
Reviewer:  Tomono ri Nagai  
 
Reviewer’s report:  
 
This manuscript explores the difference in vaginal microecology among childbearing -age women 
with different degree of cervical intraepithelial neoplasia or cervical cancer.  
 
The approach to the study is intere sting and still novel.  
 
On the other hand, I think that this manuscript has a few problems as indicated below.  
 
First, the presented tables are visually difficult for me to understand (esp. table 2 is very busy). 
Please devise the way of presentation in tab les more clearly.  
 
Next, in table 1, I think that the HPV negative rates of LSIL group and HSIL group are higher 
than the usual. Are those correct?  
 
The manuscript provides very interesting data but it still needs a considerable revision to 
acceptable.  
 
Are the methods appropriate and well described?  
If not, please spec ify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data s hown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain o r lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the man uscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the  above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will  be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available unde r an Open Access Creative Commons 
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which I do not wish to be included in my named report can be included as  confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal