Reviewer’s report
Title: 
Successful laparoscopic management of acute abdominal pain due to
spontaneous rupture of subserosal vessels overlying a uterine fibroid: a case
report and surgical video
Version: 
0 
Date: 
13 Mar 2022
Reviewer's report:
I read with great interest the manuscript, which falls within the aim of this
Journal. In my honest opinion, the topic is interesting enough to attract the
readers' attention. Nevertheless, authors should clarify some points and improve
the discussion, as suggested below.
Authors should consider the following recommendations:
- Manuscript should be further revised in order to correct some typos and
improve style.
- Accumulating evidence suggests that some intrinsic abnormalities of the
myometrium, abnormal myometrial receptors for estrogen, and hormonal
changes or altered responses to ischemic damage during the menstrual period
may be responsible for the initiation of (epi)genetic changes found in uterine
myomas. I would stress this point of paramount importance, referring to: PMID:
28875276; PMID: 25922306.
- To date, the pre-operative diagnosis and post-operative management of uterine
sarcomas represent still a challenge. I truly think that it would be necessary to
add few lines about the risk of facing off of a misdiagnosed sarcoma during the
management of uterine myomas and how to proceed (authors may refer to:
PMID: 32497607; PMID: 33098396)
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