Reviewer’s report
Title: 
Investigation of the relationship between hot flashes, sweating and sleep
quality in perimenopausal and postmenopausal women: the mediating effect of
anxiety and depression
Version: 
1 
Date: 
07 Apr 2021
Reviewer's report:
The authors have replied to the previous reviews however there are several
instances in which the problems pointed out by the reviewers are not corrected
within the revised manuscript. 
- Regarding the exclusion category of anxiety and depression. Was this a
documented history of anxiety and depression or self-reported anxiety and
depression?
- The authors state in the introduction that, "the purpose of this study is to verify
whether anxiety and depression play a mediating role between hot flashes,
sweating 
and sleep quality". However, as stated by a previous reviewer and by the authors
the current study design is not set out to determine if anxiety and/or depression
mediates this role. As such the authors should restate the purpose/goal/objective
of the study so that it actually reflects what the study design was able to yield.
This will in turn lead to a change in the expected results of the study.
Minor
- Page 6 line 27: Add system after "....autonomic nervous...". Also this sentence
is rather long, please consider breaking it into 2 sentences and leading with the
incidence of women who are affected by these symptoms.
- There are several grammar mistakes throughout the manuscript
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