JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Factors Influencing Abortion Duration, Bleeding Volume, Pain Scores, and Anxiety
Levels During Medical Abortion: A Cross-Sectional Study
Version: 3 Date: 22 Sep 2024
Reviewer's report:
Comments to the author(s)
Abstract
1- It should be written in connection with the research field in the introduction
2- The objectives of the research are not in line with the title
3- The title should be changed so that the findings and objectives are consistent with the title
4- The conclusion is not in line with the title and objectives of the research and is completely
irrelevant
5- The subject of the study is abortion, not unwanted pregnancy. Please write the beginning of
the introduction in relation to abortion statistics and its problems, not unwanted pregnancy.
6- Mention the study on physical activity and abortion in the introduction and talk about the study
Material and methods
7- During the abortion of women, the act of walking as a physical activity is actually a type of
intervention. How is a cross-sectional study?
8-  This is an intervention work and a clinical trial and needs a registry
Results
9- We got the results that total walk steps can increase the abortion time (rs=0.379, P<0.001),
bleeding(rs=0.095, P<0.05), and pain score(rs=0.206, P<0.001) in the progress of DA. got it
Discussion
10- The purpose of the study is to investigate the activity in abortion complications, in this
context, the case is not mentioned in the discussion section
Conclusion
11- It is better to write the conclusion as a statement rather than a summary of the results
12- In connection with the following two cases, there was no discussion in the results
1. Individuals with a history of dysmenorrhea and those who engage in walking at a higher pace
per minute may experience a shorter duration of abortion.
3. On the other hand, a history of dysmenorrhea, longer gestation duration, and increased walking
steps were identified as risk factors for experiencing pain during DA.
In terms of grammar and writing, it needs fundamental corrections
Title: Factors Influencing Abortion Duration, Bleeding Volume, Pain Scores, and Anxiety
Levels During Medical Abortion: A Cross-Sectional Study
Version: 3 Date: 23 Sep 2024
Reviewer's report:
Your abstract is vague and incomplete, failing to summarize your work effectively and requiring
major revisions. The  key words is not mesh-based. The 71% prevalence of dysmenorrhea
is unusual. Did you assess the dysmenorrhea in term of  VAS score and the symptoms
of endometriosis and adenomyosis evaluated or not? What do you mean by 6.2% uterine
complications? Table two does not clearly indicate any positive or negative correlations between
all factor can predicting the time of abortion; this section needs clarity, repetition should be
avoided, and the tables revised for accuracy. In Table 1, "time of C/S" is incorrect. What
is the novelty and significance of your article? How was the anxiety score calculated? The
questionnaire should be validated, and scoring must be appropriately done.You didn't mention
the patients' activity levels or step counts. Were the hospitalized patients complete bed rest?
Title: Co-developing a digital mindfulness- and acceptance-based intervention for
endometriosis management and care: A qualitative feasibility study
Version: 1 Date: 03 Mar 2025
Reviewer's report:
Thank you for the opportunity to review this study. The study is interesting and makes a valuable
addition to the field. However, there are some aspects that should be taken into consideration:
Table 2: In the "Type of Education" section, do you mean 5 years of school after high school
or a total of 5 years of school?
Table 2: In the "Type of Work" section, you describe work ability rather than the type of work.
Quote in lines 225-226: Is "it is legal" the correct translation? It sounds a bit like a mistranslation
from Danish to English.
Discussion, lines 379-382: It’s hard to understand how a participant felt overwhelmed due to
not needing an intervention for endometriosis. How does this relate to feeling overwhelmed?
You justify this result based on sampling bias and lack of systematic screening. What kind of
screening was not performed? With 7 people in your sample and 2 of them feeling overwhelmed,
perhaps you should discuss whether the intervention itself could lead to these feelings, or
acknowledge that you do not have enough informants to discuss patient education thoroughly,
suggesting it should be investigated in future studies.
Discussion, lines 386-387: Two out of 7 participants had difficulties due to disruptions at home
and lack of motivation. This is almost 30% of your sample. Even in a qualitative study, the
problem may be with the intervention itself, and this should be discussed.
Limitations: There is no discussion about the amount of data collected (7 participants) and the
ability to draw conclusions. This study provides indications, but results should be interpreted
with caution. This should be clearly stated.
Conclusions: If almost 30% of your sample describes problems with being overwhelmed or
adhering to treatment, you cannot claim only positive aspects of the treatment in your conclusion.
Title: Pelvic organ prolapse (POP) symptom progression and treatment satisfaction from the
patients’ perspective
Version: 3 Date: 08 Mar 2025
Reviewer's report:
Thank you for submitting this article for publication.  I have several  comments and suggestions
for improving this paper.  My main concern is that is makes very strong statements for something
that is based on small numbers in a very biased population.  I have listed all my comments /
questions / suggestions below
pg 4 line 71 add to the end of sentence - 'or may be unrelated'.
pg 5 line 85 - what about urinary urgency and recurrent UTI's
pg 6 line 100 - do patients expectations change over time? does their satisfaction with
conservative treatment reduce over time?
pg 6 line 111 - i would not call PFMT and pessaries methods - they are recognised conservative
treatments
pg 7 line 128 - who diagnosed the POP, what was the degree of POP and was their standardisation
for assessment methods and if PFMT was the treatment modality was this supervised or non
supervised?
pg 9 line 171 - how many women are on the facebook group in total - ie what % of this population
responded
pg 11 line 242 - was there any correlation to symptoms severity and help seeking behaviour
pg 12 line 252 - typo
pg 12 line 256 - how can a urethral repair address anorgasmia?
pg 13 line 275 - how long had they worked on conservative therapies - were they supervised
and how compliant was the patient?
pg 13 line 286 - surely this highlights a need for public health education?
pg 14 line 290 - you have not defined if you are assessing POP but natomical findings, symptoms
or both - i would comment on the paper  below.
Brown, H.W., Hegde, A., Huebner, M., Neels, H., Barnes, H.C., Marquini, G.V., Mukhtarova,
N., Mbwele, B., Tailor, V., Kocjancic, E. and Trowbridge, E., 2022. International urogynecology
consultation chapter 1 committee 2: Epidemiology of pelvic organ prolapse: prevalence,
incidence, natural history, and service needs. International Urogynecology Journal, pp.1-15.
Pg 15 - you have no mention of limitations of this study eg small number,  recall bias, population
bias  (low satisfaction) eg if patients were happy why are they still on a pt FB group?  in line
330 you suggest changing clinical pathways but you first need an understanding of the general
population first to see if your findings are generalisable and reproducible so you should be
suggesting a prospective trial in a wider health setting to understand this first or consider suggest
some preventative public health education.
pg 15 line 337 - need to add in this cohort.
pg 16 line 340 - were this pt bought devices vs hospital fitted pessaries - were they pts who may
be unfit for surgery or unsuitable at present?
pg 16 line 344 - what about other health priorities or being asymptomatic?
pg 16 line 347 - what about correlating it to the degree of POP.  You have also not made any
recognition that many women may be asymptomatic of POP and may then progress to develop
symptoms
pg 19 table  how would a TVT help a feeling of a bulge and pelvic pain?
Title: Gut Microbiome in Patients with Early-Stage and Late-Stage Endometriosis
Version: 2 Date: 04 Jun 2024
Reviewer:  Zheng Li
Reviewer's report:
The paper titled "Gut Microbiome in Patients with Early-Stage and Late-Stage Endometriosis"
explores the differences in gut microbiota compositions between early-stage and late-stage
endometriosis patients using 16S rRNA gene sequencing. The study investigates how these
differences correlate with dysmenorrhea symptoms. It highlights significant variations in the
gut microbiome structures and functions between early- and late-stage endometriosis patients
and suggests a potential role of gut microbiota in the progression and symptomatology of
endometriosis. Authough the absence of a healthy control group makes it challenging to
distinguish whether the observed microbial differences are specific to endometriosis or general
to gut health, the paper is clear and well-organized, and the quality and novelty of the research
are high, while the study is reasonably reproducible. In summary, this paper makes a valuable
contribution to the understanding of endometriosis by highlighting the distinct gut microbiota
profiles associated with early and late stages of the disease. The strengths of the study include
its innovative focus, comprehensive methodology, and significant findings.
Title: Gut Microbiome in Patients with Early-Stage and Late-Stage Endometriosis
Version: 2 Date: 19 Jun 2024
Reviewer's report:
This manuscript “Gut Microbiome in Patients with Early-Stage and Late-Stage Endometriosis”
investigates the relationship between gut microbiota and endometriosis, a chronic inflammatory
gynecological disease. This study uniquely focuses on the differences in gut microbiota between
early-stage and late-stage endometriosis patients, with an additional analysis of dysmenorrhea
symptoms. By using amplicon sequencing of fecal samples from patients categorized by the
American Society for Reproductive Medicine (ASRM) staging system, the study aims to provide
insights into how gut microbial compositions and functions vary across different stages of
endometriosis and demonstrates significant differences in gut microbiota between early-stage
and late-stage endometriosis patients. Notably, late-stage patients with dysmenorrhea exhibit
unique gut microbial profiles. These findings suggest that gut microbiota alterations, particularly
in steroid biosynthesis pathways, may play a role in the progression of endometriosis, warranting
further investigation.
Overall, the manuscript is well-written and presents interesting and important results. However,
some details of the analysis and limitations of the methodology are missing, which are important
for appropriate interpretation of the findings.
Major Comments:
1. The timeline for participant enrolment is clearly stated in the methods section. However, could
you provide a more precise definition of the process for determining eligibility and the number
of participants screened versus enrolled.
2. Can authors provide what specific protocol was followed for fecal sample processing?
3. The statistical methods are well-described, but the rationale for choosing specific tests for
certain comparisons could be expanded. For example, why were Student's t-tests chosen for
some analyses while Wilcoxon rank-sum tests were used for others? Was normality of the data
assessed prior to choosing these tests?
4. What statistical methods were used to determine the significance of the functional predictions
(metabolic pathways, enzymes, KEGG orthologs)? Could you also include the p-values in the
text?
5. Can authors provide more details on the correlations mentioned between specific genera and
r-AFS and CA125 levels? What statistical methods were used?
Minor Comments:
1. Ensure consistent use of terminology (e.g., "fecal" vs. "stool" samples).
Title: Sexual dysfunction in women with genital warts: a cross sectional study
Version: 1 Date: 08 Oct 2024
Reviewer:  Giulia Ciccarese
Reviewer's report:
Interesting article about a very common and disabling condition. I think the authors should
consider in their discussion other recent studies on quality of life , mood and sexual function in
patients with sexually transmitted infections (STIs), also different from HPV.
Mehta SD, Nordgren RK, Agingu W, Otieno F, Odongo W, Odhiambo F, Bailey RC. Sexual
Quality of Life and Association With HIV and Sexually Transmitted Infections Among a Cohort
of Heterosexual Couples in Kenya. J Sex Med. 2018 Oct;15(10):1446-1455. doi: 10.1016/
j.jsxm.2018.08.007. Epub 2018 Sep 12. PMID: 30219666; PMCID: PMC6193463.
For example, a recent study demonstrated that Symptoms of depression were common and
severe in STIs patients and that Sexual functioning is severly depressed compared to patients
with other diseases involving the ano-genital area such as inflammatory bowel diseases.
Ciccarese G, Drago F, Copello F, Bodini G, Rebora A, Parodi A. Study on the impact of sexually
transmitted infections on Quality of Life, mood and sexual function. Ital J Dermatol Venerol.
2021 Dec;156(6):686-691. doi: 10.23736/S2784-8671.20.06796-6. Epub 2020 Dec 14. PMID:
33314893.
Title: Sexual dysfunction in women with genital warts: a cross sectional study
Version: 1 Date: 18 Oct 2024
Reviewer's report:
I read the manuscript with great interest, which falls within the aim of this journal and offers a
high-quality overview of the topic.
The abstract satisfactorily summarizes the contents of the manuscript.
Although the manuscript can be considered already of high quality, I would suggest taking into
account the following minor recommendations:
- The whole text should be corrected by a native English speaker to make the work clearer and
more readable.
- Many typos should be corrected.
- Inclusion/exclusion criteria should be better clarified by extending their description.
- The introduction could be studied in depth. I find it interesting to discuss the safety and patient
satisfaction of fractional CO2 laser treatment for vulvo-vaginal atrophy in postmenopausal
women, with no severe complications and high levels of patient satisfaction (see PMID:
36037664)
-What are the implications of these findings for clinical practice and/or further research? It is
important to report the results obtained by the authors in the context of clinical practice and to
adequately highlight what contribution this study adds to the existing literature on the topic and
future study perspectives.
- Discussions can be expanded and improved by citing relevant articles about the use of fractional
CO2 laser for the treatment of sexual dysfunction symptoms in young women (see PMID:
36037664)
- The authors have not adequately highlighted the strengths and limitations of their study. It
would be better to explain these points.
Title: Sexual dysfunction in women with genital warts: a cross sectional study
Version: 3 Date: 21 Mar 2025
Reviewer's report:
"PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: I carefully evaluated the revised version of this manuscript.
The authors have performed the required changes, improving significantly the quality of the
paper.
ADDITIONAL REQUESTS/SUGGESTIONS:
I do not have further concerns."
Title: Identifying Key Palmitoylation-Associated Genes in Endometriosis through Genomic
Data Analysis
Version: 2 Date: 27 Sep 2024
Reviewer's report:
In this manuscript, different analytical methods were used to explore the expression of
palmitation-related genes in endometriosis, as well as the upstream and downstream of the key
genes. Additionally,  the correlated therapeutic targeted drugs were demonstrated.
This is a well-written paper containing interesting results. However, a number of points need to
be clarified  and  certain statements require further investigation.
1. In figure 4f, half of the key genes can't be validated in the  GSE 25628. Please explain the
potential reason and add the clinical samples for validation.
2. Since the key genes were downregulated in the endometriosis lesions, and the targeted drug
more often downregulated the targeted genes.  What's  the significance of finding relevant drug
therapeutic target#
3. The study  mainly focused on the  palmitoylation-associated genes.  Please clarify the
correlation between the pathogenesis of disease and the genes.
4. In the material and methods part,  "|log2(FC)| > 1 and P < 0.05"needs to be rewritten.
Title: Identifying Key Palmitoylation-Associated Genes in Endometriosis through Genomic
Data Analysis
Version: 3 Date: 04 Feb 2025
Reviewer's report:
Check grammar and all abbreviations.
The research gap must be mentioned.
Why was the p-value used instead of the adjusted p-value?
Why were these machine learning methods used for analysis?
All software must be cited.
The usage date and version of the software must be mentioned.
The discussion must be improved by emphasizing the findings.
All R code must be added as txt file in reviewer response.
Title: Incidence and risk factors of postpartum urinary retention following cesarean section#A
retrospective Nationwide Inpatient Sample database study
Version: 0 Date: 14 Feb 2025
Reviewer:  Ahmed M. Maged
Reviewer's report:
Many points need clarifications
1. The study design is not cohort, it is case control as the groups were classified according to
outcome
2. In abstract write the exact numbers for each risk factor and its P value
3. What was the definition used for urinary retention and its reference
4. More details about inclusion and exclusion criteria
5. Many variables are missing .These include
a. BMI
b.Duration of surgery
c .Type of anaesthesia
d IV fluids type and volume (intraoperative and postoperative
e. Time of catheter removal
f. Drugs used intra and post operative
g. Type and indications for CS
h. Bladder dissected or not
i. Bladder catheterized or not
j. Intraoperative complications
k. Doses and drugs used in epidural cases and time for epidural catheter removal
l. Time of ambulation
m. Time of oral feeding
n. Time of breast feeding
Title: Incidence and risk factors of postpartum urinary retention following cesarean section#A
retrospective Nationwide Inpatient Sample database study
Version: 2 Date: 15 Mar 2025
Reviewer:  Süleyman Serkan Kara#i#N
Reviewer's report:
Dear authors, I wish you continued scientific work. I shared my views on the article with the
editor. With my best wishes.
Title: Incidence and risk factors of postpartum urinary retention following cesarean section#A
retrospective Nationwide Inpatient Sample database study
Version: 2 Date: 07 Apr 2025
Reviewer:  Anup Pradhan
Reviewer's report:
The manuscript adds substantial value to understanding PUR after cesarean sections. It
successfully highlights modifiable risk factors, promoting better perioperative care practices.
Although the limitations restrict certain aspects, the study's acknowledgment of these constraints
boosts its credibility and paves the way for future research avenues.
The authors are encouraged to consider ways to address these weaknesses in future studies while
continuing their commitment to scientific accuracy and transparency.
Title: Incidence and risk factors of postpartum urinary retention following cesarean section#A
retrospective Nationwide Inpatient Sample database study
Version: 2 Date: 08 Apr 2025
Reviewer's report:
Abstract
Results: in second sentence use prevalence when referring to 0.2% of urinary retention. Do not
repeat all results but summarise them such as is done in the conclusions but including a few
ORs and CIs.
Data analysis
In first sentence do not refer to the prevalence of urinary retention as incidence, it is prevalence.
Results
Again, change incidence to prevalence when referring to urinary retention.
Tables
Delete Table 2 and put numbers and percentages from Table 2 into Table 3. Add footnotes to
Table 3 to indicate what covariates are included in the logistic regression models used to produce
the ORs. What factors are you adjusting for?
Results
In the results section, combine discussion for Table 2 and Table 3 into one paragraph (paragraphs
starting with ‘two groups of‘ and ‚adverse outcome‘. The p-values from table 2 and the Ors from
table 3 are essentially testing the same thing, these are the same results you are discussing.
In sections ‚ preoperative comorbidities‘ and ‚intraoperative‘ do not discuss factors that are not
significantly associated with the disease in the text.
Title: The Effects of Progressive Muscle Relaxation Exercises on Premenstrual Syndrome
Symptoms and Violence Tendencies in Women: A Randomized Controlled Trial
Version: 2 Date: 16 Feb 2025
Reviewer's report:
-The literature should be adequately examined, such as utilizing meta-analysis information
including PMS severity, providing more detailed risk factors for PMS, and utilizing the APA
guideline.
-How was the power analysis done? Why wasn't similar work used?
- Randomization should be appropriately explained
-Language control should be done by a native English speaker.
-Other suggestions and corrections are stated in the article, please review it carefully.