Reviewer ’s report  
 
Title: Fertility Preservation in Hong Kong Chinese Society: Awareness, Knowledge and  
Acceptance  
 
Version: 0 Date: 17 Oct 2019  
 
Reviewer: Seido Takae  
 
Reviewer's report:  
 
【General Comments 】 
This is a very important work that investigates the current situation of fertility preservation in 
Hong Kong. However, major revisions are needed to make this work worthy of publication.  
 
#1, Methods  
Could you explain how to select or recruit the contributors for present investigation. It's difficult 
to assess the bias of present study based on lack of information about contributors. Also, pl ease 
state target of this study on the title or abstract or introduction, like as "Awareness, Knowledge 
and Acceptance on society/medical stuffs of Hong Kong".  
 
#2, Result  
About table 1, although you demonstrated occupation of contributors. How many medica l stuffs 
are included in this population (if possible please clarify). Normally, the prevalence of medical 
stuffs may effect the interpretation of outcome on such a study.  
 
#3, Result  
About table 1, please explain about "total family income", to support th e interpretation this table. 
Can I confirm of credit the money (HKD or USD)?? In generally, family income may be effected 
the economical state and cost of living on each countries. Therefore, absolute value is not so 
important for international paper. I re commend you to define the economical state of contributors 
"high income" "middle income" "low income" based on some criterion.  
 
#4, Result Line164  
Normally, delay of cancer treatment is not accepted, if this delay affected the cancer. The 
patients should t ry fertility preservation in the period, which is permitted by oncologists. If 
patients can accept the delay of cancer treatments, oncologist and reproductive medicine 
specialists need to decide appropriate fertility preservation procedure.  
 
#5, Result  
Please clarify the current status of fertility preservation in Hong Kong. How many facilities are 
available for fertility preservation treatment (including unestablished fertility preservation 
options)? What society control the quality of fertility treatment including fertility preservation? 
Current status of fertility preservation on the aspect of medical issue is important to make 
interpretation of present outcome.  
 
#6, Discussion  
Please mention and describe about society and low about fertility treatment in cluding fertility 
preservation. I know that there is society to promote of fertility preservation treatment named as 
"Asian society for fertility preservation: ASFP".  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which c ontrols are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recom mend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financi ally from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organiz ation that 
holds or has applied for patents relating to the content of the manuscript?  
5. Do you have any other financial competing interests?  
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of th e above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests.  
 
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