Title: Attitudes of Women Towards Uterus Transplantation in Turkey: A Cross-sectional Study
Version: 2 Date: 02 Mar 2025
Reviewer's report:
Peer Review Comments
I found the survey on attitudes towards uterus transplantation in Turkey to be very interesting.
Given the medical and ethical challenges associated with uterus transplantation, it has not yet
become widespread globally. Therefore, understanding public awareness and perceptions of
uterus transplantation is important. Since ethical and religious backgrounds vary from country
to country, attitudes and opinions on uterus transplantation are also likely to differ. While
there have been previous reports from Japan, an independent study conducted in Turkey holds
significant value.
To enhance the precision and significance of this paper, I suggest making the following revisions.
Additionally, the manuscript has not undergone proper English proofreading, and there are
numerous instances of inappropriate phrasing. Please have the manuscript reviewed for language
accuracy.
General Revisions
1. Throughout the manuscript, including the title, standardize the English spelling to Turkey
instead of "Türkiye."
2. Ensure consistency in terminology—use either "uterine transplantation" or "uterus
transplantation" consistently throughout the text.
Abstract
3. Lines 11-12: There are two sentences beginning with "Most of the women...". Please include
specific percentages in these sentences.
4. Lines 16-17: The phrase "It is suggested to increase the awareness of women on uterus
transplantation." should specify the purpose of raising awareness. I assume it is to consider
uterus transplantation as one of the options for having children.
Background
5. Lines 3-4 and 18-19: The number of cases should be updated using the latest data. I
recommend citing the following paper:
o Reprod Med Biol. 2025 Feb 11;24(1):e12636.
6. Line 13: The Swedish team did not perform nine uterus transplants in 2014. The first
procedures began in 2012, and the first live birth was reported in 2014. Please correct the
description.
7. Lines 15-16: If only the U.S. and Brazil are mentioned, please include the respective years
when these cases were performed.
8. Lines 17-18: The International Society of Uterus Transplantation (ISUTx) was established in
2016, not 2017. Please verify and correct the information.
Study Setting and Sampling
9. Line 4: The Abstract states that the study was conducted both face-to-face and online, but this
section only mentions online data collection. Which is correct? Please ensure consistency.
Results
10. Please analyze whether opinions differ based on marital status, number of children, and age.
11. Lines 8-9 and Figure 1: When considering options for women who cannot conceive even
with assisted reproductive technology (ART), adoption, surrogacy, and uterus transplantation
should be distinct categories. It is inappropriate to group them together in a pie chart. Instead,
show results for which option participants support after ART failure.
• Figure 1: The meaning of the numbers in the right and bottom pie charts is unclear. Does "79,4"
mean 79.4%? If so, the total exceeds 100%, which is problematic.
• Figure 2: Add a label for the y-axis unit.
• Table 3: There are non-English terms present, such as "Living en uzun." These should be
corrected.
References
12. Ensure uniform formatting for journal abbreviations. Some journal names are not abbreviated
properly.