JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: A cross-sectional study of symptoms and health-related quality of life in menopausal-
aged women in China
Version: 4 Date: 07 Sep 2023
Reviewer's report:
Thank you for asking me to review this study which aims to assess symptoms and health-related
quality of life in menopausal-aged women in China. The research uses a cross-sectional survey
approach and involves 2,000 Chinese women over the age of 45. Participants completed the
EQ5D5L health-related quality of life questionnaire, and statistical analyses were conducted to
evaluate the impact of menopausal status and symptoms on health-related quality of life.
Questions to the author:
1. Did you make efforts to ensure that the sample was representative, and if not, how might this
impact the generalisability of the findings?
2. Given the dynamic nature of menopausal experiences, have you considered the possibility of
collecting longitudinal data to track changes in symptoms and quality of life over time? How
might this enhance the study's findings?
3.  While you mention data validation and cleaning processes, can you provide more details on
the specific steps taken to ensure data accuracy and integrity?
4. Have you collected additional demographic variables, such as socioeconomic status,
education, and geographic location, which could help contextualize the study's findings and
identify potential disparities in menopausal experiences?
5. Could you discuss the participants' access to healthcare services and their knowledge of
menopause-related treatments, as these factors could influence their symptom experiences and
quality of life?
6. Could you provide insights into the characteristics of participants who were excluded at
various stages of the screening process? How might their exclusion affect the study's results and
conclusions?
7.  What are the potential directions for future research in this area, and how might it address
some of the limitations identified in this study?
Title: A cross-sectional study of symptoms and health-related quality of life in menopausal-
aged women in China
Version: 5 Date: 06 Oct 2023
Reviewer's report:
Thank you for asking me to review the changes made to this manuscript. The participants have
addressed all comments and I am satisfied with the changes made to the manuscript. The have
discussed potential future directions for the study and how these would address the limitations.
Title: A cross-sectional study of symptoms and health-related quality of life in menopausal-
aged women in China
Version: 5 Date: 10 Oct 2023
Reviewer:  Xingyue Song
Reviewer's report:
In the results section of the paper, the authors write that: “Sample data was collected between
01 October 2020 and 25 December 2020.” But in the point-by-point reply letter, the authors
write that: “Fortunately, our data collection took place from October 2019 to December 2019
therefore our study data is arguably unaffected by the outbreak of COVID19, which was publicly
in January 2020.” This makes me very confused. When was the data collection time for this
study.
Title: Cornual invasive hydatidiform mole: A rare case report and literature review
Version: 2 Date: 04 Mar 2023
Reviewer's report:
Dear authors,
The report has been well drafted.
Kindly consider the following that might help improve the content of your report.
1. Since the review of pathological sections from the first curettage revealed a complete
hydatidiform mole, was there a reason why this case was not diagnosed and treated over two
months after the abortion?
2. Was any imaging study performed to support the diagnosis when she had an abortion two
months back?
3. It would be better to mention the stage of the disease at diagnosis.
4. As the patient has received chemotherapy, consider providing the WHO prognostic score of
the patient.
5. Also, mention the total course of chemotherapy received by the patient.
6. If possible, you could provide an image of the pathological section supporting your diagnosis.
Title: Cornual invasive hydatidiform mole: A rare case report and literature review
Version: 2 Date: 02 Jun 2023
Reviewer:  Reda Hemida
Reviewer's report:
Hemida R, Fyala E, Ragab A, Abu-Taleb H. Local Myometrial Resection
for Chemo-resistant Gestational Trophoblastic Neoplasia: Case Series and
a Surgical Video. J Gynecol Case Rep. 2023; 2(1): 1005. Available
at: https://meddocsonline.org/journal-of-gynecology-case-reports/local-myometrial-resection-
for-chemo-resistant-gestational-trophoblastic-neoplasia-case-series-and-a-surgical-video.pdf
Title: Cornual invasive hydatidiform mole: A rare case report and literature review
Version: 3 Date: 19 Sep 2023
Reviewer:  Aleksandar Rakic
Reviewer's report:
The authors have improved the manuscript. Nevertheless, there are still some minor issues that
require change.
1. Introduction, lines 45-47: I would suggest changing the sentences into: "In general practice,
practitioners used to use the term cornual pregnancy to refer to the gestations that occur near
the uterine cornua, which is the junction of the oviduct and uterus. Cornual pregnancy presents
a complex diagnostic and management challenge, due to its inherent relationship to interstitial
ectopic pregnancies."
2. Introduction, lines 52-55: please place the appropriate reference at the end of the sentence.
3. Discussion: I still think the two papers I mentioned should be placed into the Discussion. In
my opinion, the authors would improve this section by comparing their case presentation and
pointing to the rarity and uniqueness of their case (there were no uterine abnormalities and, on
the other hand, their case was about the invasive mole).
Besides these remarks, in my opinion, the paper should be considered for publication.
Title: Cornual invasive hydatidiform mole: A rare case report and literature review
Version: 4 Date: 12 Oct 2023
Reviewer's report:
-There is no data on the initial  serum beta hCG value  before  curettage as well as after HP
confirmed complete hydatidiform mole.
- There are no data of regular Followe up programme after molar pregnancy
64- According to beta-hCG plasma level ( 7584 IU/L when patient was admitted to the hospital
because of vaginal bleeding)  two months after curettage ,  GTN= Invasive mole  developed as
a possible   complication post molar pregnancy.
64- This patient "received an abortion two months ago".
There are no reports that it was cornual pregnancy!!! Metastatic   cornual invasive mole could
develop  even after normal  pregnancy  as well as after  molar pregnancy ( as in this case)
-I think that  this  paper  I marked **should be placed into the Discussion.
**
Page 296 VOJNOSANITETSKI PREGLED Vojnosanit Pregl 2022; 79(3): 296–300.
Correspondence to: Branka Nikoli#, Gynecology and Obstetrics Clinic “Narodni front”,
Department of Conservative Gynaecology, Kraljice Natalije Street 62, 11 000 Belgrade, Serbia.
E-mail: b1.nikolic@gmail.com CASE REPORT    UDC: 618.1/.2 DOI: https://doi.org/10.2298/
VSP200629097R Therapeutic approach to the iatrogenic invasive mole – A report of two cases
Terapijski pristup jatrogeno nastaloj invazivnoj moli – prikaz dva slu#aja   Aleksandar Raki#*,
Branka Nikoli#*†, Ognjen Radoji#i#*, Marko Džuverovi#* *Gynecology and Obstetrics Clinic
“Narodni front”, Belgrade, Serbia; †University of Belgrade, Faculty of Medicine, Belgrade,
Serbia
Title: A preoperative nomogram predicting risk of lymph node metastasis for early-stage
cervical cancer
Version: 2 Date: 15 May 2023
Reviewer's report:
- Rationale of predictive diagnostic model should be information about choice of treatment such
as radiation versus surgery more than perform or omitted lymphadenectomy.
- Omitted  lymphadenectomy  is not the standard of treatment for early-stage cervical cancer.
- FIGO staging should be specified in stage IA2-IIB more than stage I-II.
- Typo in line 92, 168
- What is the exclusion criteria of this study?
e.g.  neuroendocrine tumor,  lymphadenectomy less than 11 nodes, abnormal preoperative
imaging, intraoperative bulky pelvic nodes
- What is the definition of tumor grading? Why did this study has tumor grade IV?
- Details of pathologists who performed pathological examination  should be described.
- Sample size calculation for developed and validated predictive model should be added.
- How to deal with missing data? Details of imputation should be explained.
Title: A preoperative nomogram predicting risk of lymph node metastasis for early-stage
cervical cancer
Version: 2 Date: 21 May 2023
Reviewer's report:
One of the essential things in this study is that the data examined is related to the last 8 years.
The results of previous studies have indicated the importance of the size and degree of tumor
spread in the prognosis of the disease, what is the difference between your study and prior
studies?
In the discussion, please do not repeat the findings discuss your findings, and report the evidence
for and against them.
What was the limitation of your study?
What were the criteria for entering and exiting the study?
How were the two groups determined?(Training And Vliditaition)
Title: A preoperative nomogram predicting risk of lymph node metastasis for early-stage
cervical cancer
Version: 3 Date: 03 Jul 2023
Reviewer's report:
This is an excellent revised manuscript, but I have some concerns regarding its implications for
practice. The authors should mention the acceptable rate of accuracy for diagnosing lymph node
metastases in early-stage cervical cancer.  In additions, information about what is the safety
of omitting pelvic lymphadenectomy when  a lower than cut-off point is obtained from this
nomogram should be described.
Title: A preoperative nomogram predicting risk of lymph node metastasis for early-stage
cervical cancer
Version: 3 Date: 27 Jul 2023
Reviewer's report:
Ref: Submission ID 04f9270d-f326-4f96-b3d9-6ff3f25d3893
Title:
"A preoperative nomogram predicting risk of lymph node metastasis for early-stage cervical
cancer"
General comments
This manuscript describes the main features of patients with cervical cancer. The paper provides
new information and evidence to put into practice. More interesting will be in practice, but for
now, have the potential for publication.
Would think the methods, results, and discussion are appropriate. However, authors need to
emphasize risk results which is the core of the research.
Additionally, a methodological limitations section is needed in the manuscript.
Specific comments
Check the wording in some paragraphs.
Attach an English proofreading certification.
Title: A preoperative nomogram predicting risk of lymph node metastasis for early-stage
cervical cancer
Version: 5 Date: 17 Oct 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: The authors had adequately addressed all my queries and made
appropriate changes in the revised manuscript. The paper in now much clearer and would be of
value to aid oncologists in patient counselling and treatment planning.
I have no further suggestions. The revised manuscript is ready for publication consideration.
ADDITIONAL REQUESTS/SUGGESTIONS:
No further suggestion
Title: The causal effect of educational attainment on stress urinary incontinence: a two-sample
mendelian randomization study
Version: 0 Date: 17 Sep 2023
Reviewer's report:
This paper uses Mendelian randomization to estimate the causal effect of educational attainment
(EA) on stress urinary incontinence. Overall the analysis is appropriate however I have questions
about the interpretation of the results. The effect estimate is tiny and the 95% confidence interval
crosses the null for many of the pleiotropy robust estimators, therefore concluding that there is
a causal effect of education on SUI seems like too strong an interpretation, or at least should
be caveated that any causal effect is unlikely to be meaningfully important and may be due to
pleiotropy.  I have a number of other comments listed below;
1. The interpretation of the effect – in terms of what the effect estimate obtained means in years
of education is not given until the discussion, this should be mentioned in the results at least and
the scale of each GWAS should be given when describing the data.
2. Given that EA is associated with parity and has been established as a causal effect for BMI,
have the authors considered exploring if any result they do find is due to the effect of EA on
parity and/or BMI, for example through multivariable MR?
3. Are all the datasets for both sexes combined? What is the prevalence of SUI in the male
participants in these datasets? Would analysis by sex be relevant for this particular application?
4. The use of the term ‘polygenic score’ in Fig 1 is misleading – the authors are using only a
small set of SNPS which are not combined into a score.
5. How much overlap is there between the exposure and outcome samples? This is likely to be
substantial for the analysis of the effect of college degree on SUI as both GWAS used are based
on UK Biobank. Does the GWAS for YOS also include a substantial proportion of participants
from UK Biobank?
Title: The causal effect of educational attainment on stress urinary incontinence: a two-sample
mendelian randomization study
Version: 0 Date: 20 Sep 2023
Reviewer's report:
I read with great interest the manuscript, which falls within the aim of this Journal and offers
a high-quality overview of the topic.
The abstract perfectly summarizes the contents of the manuscript. Methodology is accurate and
conclusions are supported by the data analysis. The tables and figures are clear and interesting.
Although the manuscript can be considered already of high quality, I would suggest taking into
account the following minor recommendations:
- I suggest another round of language revision, in order to correct few typos and improve
readability.
- I find it interesting to include a reference to the use of Ospemifene for the treatment of urinary
symptoms (see PMID: 30324854) and about surgical options to improve patients' quality of life
(see PMID: 33103408).
- Discussions can be expanded and improved by citing relevant articles about the procedures
actually in use for the management of urinary incontinence (I suggest authors to read PMID:
32744453).
- The authors have not adequately highlighted the strengths and limitations of their study. I
suggest better specifying these points.
Title: The causal effect of educational attainment on stress urinary incontinence: a two-sample
mendelian randomization study
Version: 2 Date: 03 Oct 2023
Reviewer's report:
I read your work with great interest and pleasure.
Thank you for going through the manuscript and the reviewers' points.
In my honest opinion, the authors have responded satisfactorily to the reviewers’ criticisms.
The manuscript is well written and falls within the aim of this Journal.
Please correct reference 3 as follows:
Monti M, Fischetti M, DI Pinto A, Santangelo G, Giannini A, D'Oria O, Golia D'Augè T,
Carbone F, Perniola G, DI Donato V, et al. Update on surgical treatment of female stress urinary
incontinence. Minerva Obstet Gynecol. 2021 Apr;73(2):140-144.
Considered all these points, I think it could be of interest for the readers and, in my opinion, it
deserves the priority to be published.
Title: Quality of life, social support, and adherence in female patients with thyroid disorders
Version: 2 Date: 09 Sep 2023
Reviewer's report:
While the majority of my comments were addressed in full by the authors, I still have  some
additional remarks regarding three of the previously raised issues. I follow the numbering that
was used by the authors in response to my earlier comments.
5. While the use of self-reported diagnostic categories is a commonality between this paper and
the article by Rigó et al. (DOI: 10.1186/s41687-023-00606-7), the risk of cross-contamination
of study groups is much higher in this case. This is because the two categories used by Rigó
et al. are, for practical purposes, mutually exclusive while the four categories used by Kollerits
et al. overlap.
The authors state that separation of patients with autoimmune conditions was necessary because
‘Hashimoto's thyroiditis and Graves' disease are often associated with autoimmune processes
that can significantly reduce quality of life.’
It is still highly debated in the literature whether organ-specific autoimmune inflammation
in these conditions can actually cause symptoms or decreased QoL independently of thyroid
function.
It is also important to note that the authors themselves have found no difference in thyroid-
dependent QoL between the autoimmune and non-autoimmune groups, which seems to
contradict their initial theory and might warrant further emphasis. Alternatively this could also
be the result of the mentioned cross-contamination.
I would recommend the authors to consider collapsing the four diagnostic categories into two
(hypo- vs. hyperthyroidism), which would address at least part of this issue.
6.1.  While the inclusion of information about treatment modalities among study participants is
appreciated, it doesn't address the specific point I was trying to raise.
The strongest known determinant of QoL in hypo- and hyperthyroid patients is thyroid function,
the normalization of which is the primary goal of most treatments. The lack of data on the thyroid
function (eg. current TSH) of the participants significantly diminishes the generalizability of the
reported results. I think this limitation should at least be clearly noted in the paper.
7. 2. From the text it is unclear whether the assessment of the relationship between adherence and
QoL involve all participants or just those who were receiving pharmacologic treatment (n=869
based on the amended Figure 1.).
The point I intended to convey here was that analyses using the Morisky Medication Adherence
Scale would be relevant  only for those patients who who have been prescribed medication for
their thyroid disease.
Title: Sexual assault and vulnerability to sexually transmitted infections among homeless
Brazilian women: a cross sectional qualitative study
Version: 2 Date: 23 Aug 2023
Reviewer:  Tarek Tawfik Amin
Reviewer's report:
BMC Women’s
Title: "Sexual assault and vulnerability to sexually transmitted infections among homeless
Brazilian women: a cross sectional qualitative study".
Comments to the authors:
Title: since the study included both cis/transgender, the title as well as the results section should
display this.
Abstract:
- Line 23: remove thus.
- Results section emphasized the violence but not mentioned in the objective of the study? Line
24: the aim of the study was to explore experiences of homeless women regrading sexual and
reproductive health and their exposure to sexually related assaults.
- In all sections STI should be changed to STIs.
- In the conclusion section, it is rather a recommendation than a conclusion, please make your
conclusion to reflect the work done.
Introduction:
- Line 14 and line 17: North American Study: please specify the country in which these studies
originated?
-  In the introduction section, explore the intervention/services/programs dedicated to this
vulnerable population in Brazil (if any).
- Line 24: the objective of the study (the aim) should be stated near the end of your introduction.
Methods:
- Line 15: a cross-sectional qualitative survey was conducted in Sao Paulo area,
- Line 22: replace sufficiency criterion by saturation point.
- What do you mean by “impotence” in table 1?
- “social gender relationship” how it was used in your analysis? It did not see any reflection in
the results section.
Results section:
- State both numerator and denominator (n=10/15, 66.7%)
- Living in the street: express it as median (if possible)
- In the results you mentioned 3 transgender while in table 2, they are 4???
- Was there any difference between cis and transgender?
- While displaying each themes, report your results by the sub-themes if possible and using
subtitles.
- Were there any differences in response to the educational status of the included participants?
- The study primarily displayed the sexual violence rather than the whole spectrum of the
reproductive health and reproductive health care??? How and where did they get these care?
Discussion
- Line 4: Meacham et al: please follow the journal instructions for writing the references.
In the conclusion section:
- What economic abuse? There is no such point in the whole manuscript.
References
- Follow the journal instruction in writing the references
- Some of the used references are pretty ancient (Safioti H.A 1979) and (Scott J. Genero 1991)
- The last reference should be translated into English.
Title: HUMAN PAPILLOMAVIRUS VACCINE UPTAKE AND ASSOCIATED FACTORS
AMONG ADOLESCENT GIRLS IN HIGH SCHOOLS OF NEKEMTE CITY, WESTERN
ETHIOPIA, 2020
Version: 3 Date: 07 Aug 2023
Reviewer:  Esubalew Tesfahun
Reviewer's report:
Introduction
The authors should clearly show the gap related to evidence fill by doing this research.
Methods
Study Design
A cross-sectional study design was conducted among adolescent girls attending aged 15 years
at high schools in Nekemte City
Need justification for why the authors conduct this research on schools.
Title: HUMAN PAPILLOMAVIRUS VACCINE UPTAKE AND ASSOCIATED FACTORS
AMONG ADOLESCENT GIRLS IN HIGH SCHOOLS OF NEKEMTE CITY, WESTERN
ETHIOPIA, 2020
Version: 3 Date: 10 Aug 2023
Reviewer:  Demisu Zenbaba
Reviewer's report:
Comment #1: Title
What does mean by middle adolescent?? Scientifically it is known that there are early and late
adolescent.
MSc, MPH??? Use one of them.
Comment #2: Abstract
Please indicate the research gap very well.
Uptake was majorly related to perception…..what about knowledge, attitude and facility related
factors???
What type of qualitative study design was used….is it ethnography, case study,
phenomological….???
Comment #3: Introduction
improve understanding about HPV vaccination….is it your objective???
Comment #4: Methods
Addis Abeeba’s……???
According to the 2023 reports….who is reporter???
metro area population….???
phenomenological study design is to explore about experiences of individuals…but your title is
perception …how this can go together???   why not Ethnography….to explore cultures that can
affect perception or uptake of HPV vaccine???
14-17 years-old and who live in Addis Ababa….why you exclude age 18 and 19???
What was the time allowed for each FGD??? Who was the facilitator??
Comment #5: Results
Students were selected from randomly selected 3 sub cities ….What  is the importance of
randomness in qualitative??