Reviewer ’s report  
 
Title: Tumor Characteristics and Treatment Outcomes of Older Patients with Breast Cancer in  
Jordan  
 
Version: 0 Date: 20 Nov 2019  
 
Reviewer: Chunhuan Lao  
 
Reviewer's report:  
 
This study examined the tumour characteristics and treatment o utcomes of women aged 65+ 
years with breast cancer in Jordan. It is important to show the results in developing countries. 
There are some problems need addressing before publication.  
Title: It would be better to indicate the study was "in Jordan" instead o f "in a developing 
country".  
Abstract: If 553 patients in total and 114 metastatic BC, then there should be 439 early stage BC, 
instead of 423.5 (144/34% in line 33). In line 37, "85.4% vs. 74.1%, P=0.0024" should be inside 
the bracket () as the figures in  the same sentence.  
Results: Apart from the factors in Table 2, were there any other factors included in the Cox 
regression, such as age and other factors in Table 1? Some factors need to be adjusted. Since 
there were only 38 patients with triple negative  disease and the hazard ratio p -value was 0.190, I 
would suggest including ER, PR, and HER2+ in the regression instead of triple negative. 
Authors mentioned DFS in line 84, but no DFS result was found anywhere in the paper.  
Conclusions: Conclusion need to be rewritten. The last sentences are not supported by the 
results.  
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
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