Reviewer’s report
Title: 
The Relationship Between Menopausal Syndrome and Gut Microbes
Version: 
0 
Date: 
24 Jul 2022
Reviewer's report:
The topic of this Manuscript falls within the aims of BMC Women's Health. The
article provides a valuable and methodologically correct data analysis, the
conclusion is consistent with data discussion and with available evidence
throughout the text. The topic of this study is novel, so it may be of great interest
for the readers.
In general, the Manuscript may benefit from several minor revisions, as
suggested below:
- Proof-reading by native English speaker is mandatory, in order to improve its
readability and correct several typos.
- Introduction: the final part of the introduction (55-61 lines) contains aims and
some results of the study (number of patients), I think it could be inappropriate to
mentions this information in this part of the article.
- Materials and Methods: line 67, also in this part I would not mention results of
the study (number of patients recruited).
- Materials and Methods: the exact type of study have to be specified (e.g.
prospective, retrospective, case-control, etc.).
- Table 1 is unreadable in all its parts, moreover it is more appropriate for the
results section.
- Bibliography: I suggest to add this relevant study to bibliography PMID:
29452786.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes