Reviewer ’s report  
 
Title: DIAGNOSTIC CHALLENGES: LOW -GRADE ADENOSARCOMA ON DEEP 
ENDOMETRIOSIS  
 
Version: 1 Date: 26 May 2019  
 
Reviewer: R. Y. K. Cheung  
Reviewer's report:  
Thank you for preparing this case report.  
1) Low -grade adenosacroma is rare condition. However, there were already a number of case 
reports published on uterine adenosacroma, extra -uterine and also extra -genital adenosacroma. A 
similar case was reported in 2007 from simply Pubmed search:  
Ultrasound Q. 2007 Sep;23(3):189 -91. 
Müllerian adenosarcoma of the ovary: case report and review of the literature.  
Shetty M1, Lal N, Vu NH.  
2) Bes ides abdominal pain, it would be good to provide more information about the menstrual 
symptoms, if any, of the patient.  
3) In this case, a 3 cm myoma was noted in the pre -op imaging and one piece of biopsy from 
uterine tissue was confirmed to be low -grade adenosacroma. The primary site of the 
adenosacroma may still be from uterus.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which co ntrols are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corre ctions before being published  
 
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