JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: The vaginal microbiome of South African pregnant women living with Human
Immunodeficiency Virus (HIV) with and without Chlamydia trachomatis infection
Version: 0 Date: 22 Apr 2024
Reviewer's report:
This study aimed to investigate differences in the vaginal microbiome of pregnant women with
and without C. trachomatis infection. The study has potential for the future; however, I have
the following comments:
1. How do the authors normalise other factors that possibly influence the vaginal microbiome
in these women, such as lifestyle and hygiene practices, to account for microbiome differences
that are not due to C. trachomatis infection?
2. Does pregnancy change the microbiome composition orchestrated by, for example, hormonal
changes? It would have been useful for the author to include C. trachomatis-infected non-
pregnant women as part of the cohort.
3. Were the women without C. trachomatis infection screened for or free of other vaginal
infections such as candida etc?
4. Which database was used for the taxonomic assignment? How did the authors deal with
discrepancies between the assignments by different databases? I would recommend using a
differential abundance tool eg Deseq2, ANCOM2 or Maaslin2, to determine taxa enrichment at
the genus level between cohorts.
Title: Toward better understanding and management of chemobrain: The potential utilities of
the MemTrax memory test
Version: 3 Date: 23 May 2024
Reviewer's report:
Dear authors,
This is an interesting prospective study assessing subjective and objective cognitive problems in
women with breast cancer receiving chemotherapy. The study sample is relatively low but the
study is strengtened by repeated testing. I have the following remarks, questions and concerns:
1) The FACT-cog measure and the MemTrax memory test should be described thoroughly in
the Materials and Methods section (and not in the Discussion section)
2) How was the data from the 4 repeated testings (for each of the chemotherapy cycles)  in each
patient handled?
3) One author  (Curtis B Ashford) is affiliated to the company that has developed  the MemTrax
test- are dere any financial conflicts of interest?
4) Ethics - did the patients deliver a written consent to participate in the study?
5) All abbreviations from the FACT Cog and the MemTrax test should be written out and
explained (both in the text and the tables)
Title: Toward better understanding and management of chemobrain: The potential utilities of
the MemTrax memory test
Version: 3 Date: 03 Jun 2024
Reviewer:  Carmen Lizette Galvez-Hernandez
Reviewer's report:
This project is valuable because it reveals the real-world evidence around chemobrain.
However, I am suggesting several changes that may improve your article. Additional information
needs to be clarified from the title to methods and discussions.
Title: Prevalence and risk factors for chronic endometritis in patients with adenomyosis and
infertility: a retrospective cohort study
Version: 2 Date: 04 May 2024
Reviewer's report:
Thank you for giving me the opportunity to review this interesting study "Prevalence and risk
factors for chronic endometritis in patients with adenomyosis and infertility".
However, I have some comments and recommendations:
Comments:
Title: - Is appropriate for the content of the article.
Abstract:- Represents a suitable summary of the work.
Article content:- The methods and results have been well explained.
Conclusions:- Are justified on the basis of the study.
Recommendations:
Methods:- Emphasize sample size.
Discussion:- Suggest clinical implications.
References:- Stick to the format of the journal.
General:- Revise language, grammar and syntax.
Title: Prevalence and risk factors for chronic endometritis in patients with adenomyosis and
infertility: a retrospective cohort study
Version: 2 Date: 05 May 2024
Reviewer:  Yigit Cakiroglu
Reviewer's report:
General comments:
The manuscript has been processed in accordance with the author guidelines of the journal.
The presentation of the work is clear, with regards to language and grammar. The manuscript
proposes information about chronic endometritis, adenomyosis and the correlation between the
two entities.
Abstract:
The abstract accurately describes the short-summarized content of the article and sufficiently
reflects the content.
Key words are adequate in quality and number and representative of the research.
Introduction:
The introduction presents the purpose of the investigation and the purpose is supported by the
pertinent literature. The rationale of chronic endometritis, diagnostic criteria, adenomyosis and
the correlation in between two pathologies have been described in the introduction section.
Materials and Methods
The materials and method section contains the type of the article, determination of the study
population. The methods section describes sufficiently the algorithm of the MS. The use of
statistics and treatment of uncertainties are appropriate.
- Would the authors please give detailed information about the technical diagnostic criteria of
adenomyosis according to MR findings?
Results
The result section contains findings and observations in regards of the results.
Discussion
The authors have reported their interesting and valuable findings in regards of correlation in
between two pathologies and discussed their findings in a detailed way in the discussion section.
References:
The references section contains appropriate and reasonable number of references and are up to
date.
Figures:
Correlation in between CE and BMI has been well described.
Tables:
Tables are well-designed.
Title: Questionnaire Survey on Cervical Cancer Screening and HPV Awareness among Patients
at a Local Cancer Center in Japan
Version: 1 Date: 25 Jun 2024
Reviewer's report:
I read with great interest the Manuscript titled " Questionnaire Survey on Cervical Cancer
Screening and HPV Awareness among Patients at a Local Cancer Center in Japan
" which falls within the aim of the Journal.
Although the manuscript can be considered already of good quality, I would suggest following
recommendations:
- I suggest round of language revision, in order to correct few typos and improve readability;
- The persistence of HPV infection is a challenge due the its crucial role on precancerous lesions
progression. Considering result of this study, I would be glad if the authors discuss this important
point with PMID: 37747763 and “State of the art on HPV-related cervical lesions, Tullio Golia
D’Augè, Ilaria Cuccu, Andrea Etrusco, Antonio D’Amato, Antonio Simone Laganà, Ottavia
D’Oria, Giorgio Bogani, Violante Di Donato, Ludovico Muzii, Andrea Giannini, doi: 10.36129/
jog.2024.16.
Because of these reasons, the article should be revised and completed. Considering all these
points, I think it could be of interest to the readers and, in my opinion, it deserves the priority
to be published after minor revisions
Title: Questionnaire Survey on Cervical Cancer Screening and HPV Awareness among Patients
at a Local Cancer Center in Japan
Version: 1 Date: 26 Jun 2024
Reviewer's report:
This manuscript documents the results of a survey administered to women who received care
for abnormal cervical screening tests and/or symptoms of cervical neoplasia at the Gunma
Prefectural Cancer Center. The findings documented in the manuscript are largely those that
would be expected. The major limitation of this manuscript is that it did not collect information
from women in the same community who chose not to undergo screening. The authors should
comment on that limitation.
Title: The efficacy of early office hysteroscopy in preventing intrauterine adhesions after
abortion: a randomized controlled trial
Version: 2 Date: 19 May 2024
Reviewer's report:
Thank you for giving me the opportunity to review this interesting RCT "The efficacy of early
office hysteroscopy in preventing intrauterine adhesions after abortion".
However, I have some comments and recommendations:
Comments:
Title: - Is appropriate for the content of the article.
Abstract:- Represents a suitable summary of the work.
Article content:- The methods and results have been well explained.
Conclusions:- Are justified on the basis of the study.
Recommendations:
Discussion:- Suggest clinical implications.
References:- Stick to the format of the journal.
General:- Revise language, grammar and syntax.
Title: The efficacy of early office hysteroscopy in preventing intrauterine adhesions after
abortion: a randomized controlled trial
Version: 2 Date: 09 Jun 2024
Reviewer's report:
The  main concern is surgical intervention for abortion which is traumatic  and there are many
protocols for non-surgical termination of pregnancy like misoprostol,....for prevention of surgery
and its complications, like IUA,so what is the reason for surgical termination instead of drugs
termination.?
Hyaluronic gel is an option for preventing intrauterine adhision or intrauterine  balloon insertion
and those are cheaper and less invasive than hysteroscopy.
Hysteroscopy is first choice for dissecting IUA, what is the reason for doing it two times?
Title: THE RELATIONSHIP BETWEEN DIETARY HABITS AND MENSTRUATION
PROBLEMS IN WOMEN: A CROSS-SECTIONAL STUDY
Version: 2 Date: 24 May 2024
Reviewer's report:
The article titled: “THE RELATIONSHIP BETWEEN DIETARY HABITS AND
MENSTRUATION PROBLEMS IN WOMEN: A CROSS-SECTIONAL STUDY” investigates
the comparison of anthropometric assessment and nutritional habits and  dietary intake between
women with and without menstrual disorders. The idea of the research is interesting. However,
there are a few questions or issues to address:
1. It is required to reword the research purpose included in the Abstract, Background, and
Discussion sections. To be consistent with the actual purpose of the research.
2. Material and Methods section: “Participants included in the study according to whether they
had menstrual disorders or not”.
• What criteria was used to assess the menstrual disorders?
• Were these criteria clearly described in the questionnaire which the Authors submited to the
readers? Please add this information to the text of the manuscript, as well as the information that
“24-hour food consumption was obtained via phone call”.
3. There is no reference for Food Frequency Questionnaire, you used in your study, as well as
24h record form. Did you use in the research validated questionnaires? Please provide a source.
4. Discussion section:
• “However, most studies have concluded by emphasising the importance of an adequate and
balanced diet” – after this kind of sentence is required to add few references.
• “An adequate and well-balanced diet is a key factor for menstrual health. High sugar intake
is related to menstrual pain and menstrual irregularities. A diet rich in fish, nuts, vegetables
and fruits is very helpful for relieving symptoms of menstrual disorders.” - What do you think,
why and how these products (healthy and also unhealthy) influence women’s health and cause
menstrual pain/irregularities?  Please expand this sentences.
5.  Conclusion section:
• It would be important to add information whether “lower/higher” intake means significantly
lower/higher or not.
Title: Association between Dietary Insulin Index and Postmenopausal Osteoporosis in Iranian
Women: A Case-Control Study
Version: 1 Date: 10 Dec 2023
Reviewer's report:
Dear authors:
This manuscript has examined the inverse relation between dietary insulin index and
osteoporosis: a case-control study in postmenopausal Iranian women. The manuscript needs
minor corrections. I suggest comments to improve the manuscript:
1. What is the reason for choosing the age range of 45-85?
2. The changes applied by the native English editor have caused errors, including the calculation
of BMI and physical activity. Please correct it.
3. You mentioned several times that this research was done for the first time, but it is better not
to state this sentence with certainty
Title: Association between Dietary Insulin Index and Postmenopausal Osteoporosis in Iranian
Women: A Case-Control Study
Version: 1 Date: 07 Jan 2024
Reviewer's report:
Authors in a case-control study investigated the association of DII with risk of osteoporosis in
Iranian women
The following points are suggested
Abstract
in methods two following sentences should be revised conceptually "Additionally, the DII for
each participant was calculated by dividing the sum of the insulin loads of all the foods consumed
(dietary insulin loads) by total calories consumed. Utilizing binary logistic regression, we looked
at the connection between DII and osteoporosis."
DII adjusted for energy intake, probably ; yes?
Logistic regression .... correct please
please present  mean scores of DII  in both groups.
Introduction
More scientific justifications are needed about the connection of IR , DII with osteoporosis
Methods
Sample selection is questionable!  controls from which place and based on which inclusion
criteria were selected. How about matching?
Those matters have been written about sample size are not correct? what do you mean from effect
size, OR, mean difference ,....? based on which reference ? effect size for what association?
Authors should explain with more details about the calculation of DII  , the presented reference is
not original , it is related to a study that itself used this index in relation to metabolic syndrome!!
Statistical analysis subsection and results
Statistical analysis subsection has major defects, you should declare that DII categorized to
tertiles then crude OR and adjusted OR how estimated.
All variables in table 1 should be introduced previously in methods section, abbreviation should
be noted in the below tables in full terms.
All variables in table 1 should be compared across categories of DII too,
Subgroup analysis based on physical activity levels and BMI categories are recommended
strongly.
Title: Association between Dietary Insulin Index and Postmenopausal Osteoporosis in Iranian
Women: A Case-Control Study
Version: 3 Date: 05 Jul 2024
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Yes, the authors have responded very well to all my concerns. The
manuscript is now very clear, and the good work of the authors can now be understood fully. I
think the manuscript is very solid and will have a very good chance of being accepted
ADDITIONAL REQUESTS/SUGGESTIONS:
I just have one very minor comment but becasue it is in the abstract, I believe it should be
clarified. On line 15, authors wrote "determines the DII indication". I am not sure what they
mean by indication. They could just remove that word "indication" and it will sound better.
Title: The impact of physical activity and exercise interventions on symptoms for women
experiencing menopause: overview of reviews
Version: 1 Date: 15 Apr 2024
Reviewer:  Beate C. Sydora
Reviewer's report:
Over the past several years, many papers and reviews have been written on the topic of exercise
in menopause. These papers have provided inconclusive and at times contradictory results of
the beneficial effect of a variety of exercises for menopausal symptoms. Collating the findings
to date in an overview of reviews is certainly adequate and timely.
All in all, I appreciate the very comprehensive analysis. Gaps in research are well identified and
included in suggestions for future research.
I have only a few comments for clarifications and further improvements.
Point 7 in the PRIOR checklist states that the full search strategy is presented; however,
supplementary table 3 only reports on example search terms. It would be useful to add the
completed search strategy in a supplementary table; including the limitation put on time, which
is mentioned - but not defined - in the text under the heading search strategy. A time limitation is
mentioned towards the end in the limitation section but should be included in the method section.
Under the heading ‘search strategy’, you may also include that you only included reviews written
in the English language (as reported in the PISMA figure 1)
I am not entirely clear if the findings are only based on RCTs, but do not include other study
designs. Perhaps this should be clarified. If other designs are included in the final summaries,
please add to table 1 the designs of studies other than RCTs.
In the discussion, it would be useful to give numbers instead of using “most” in line 2,4 and 10.
In the limitation it is rightfully mentioned that activities were not well or systematically
described. A narrative review on walking as a potential benefit for menopause symptoms
published in ‘Menopause’ 27(8):952 in 2020 mentioned the variations in exercise duration and
length of frequencies as a challenge to explicitly agree on a beneficial outcome. Variation in
intervention length and frequencies of exercise might be worth discussing as a limited issue.
The reference used for the MENQOL questionnaire is merely a validation of the MENQOL
for breast cancer survivors. It would be adequate to cite either the original development and
validation of the MENQOL and/or one of its updated versions:
Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, et al. A menopause-
specific quality of life questionnaire: development and psychometric properties. Maturitas.
1996;24(3):161–175.
Lewis JE, Hilditch JR, Wong CJ. Further psychometric property development of the Menopause-
Specific Quality of Life questionnaire and development of a modified version, MENQOL-
Intervention questionnaire. Maturitas. 2005;50(3):209–221.
Sydora BC, Fast H, Campbell S, Yuksel N, Lewis JE, Ross S. Use of the Menopause-Specific
Quality of Life (MENQOL) questionnaire in research and clinical practice: a comprehensive
scoping review. Menopause. 2016 Sep;23(9):1038-51.
Title: The Impact of Exercise on Growth Factors in Postmenopausal Women: A Systematic
Review and Meta-Analysis
Version: 0 Date: 07 Oct 2023
Reviewer's report:
Thank you for your insightful work, well written with thorough research
I have few comments, if you please:
1-Please review these sentences (lines 51-53) as each sentence contain different percentage for
the same parameter
2-The message that I get from this study that there is no statistically significant correlation
between physical activity in postmenopausal women and IGF-1 levels, but the conclusion of the
study implicate that there is some sort of correlation.
Could you please explain this?
Title: The Impact of Exercise on Growth Factors in Postmenopausal Women: A Systematic
Review and Meta-Analysis
Version: 0 Date: 10 Oct 2023
Reviewer:  Ali B. Roomi
Reviewer's report:
Thank you for asking my opinion #about #the #manuscript #entitled ##"Effects of Exercise
on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor- Binding Protein-3 in
Postmenopausal Women: A systematic review and meta-analysis of randomized-controlled
trials". #
#I believe that this manuscript should #be #major revision:#
Q1. It is very important to change and modify the title. The title #is not appropriate.#
Q2. Are the objectives and the rationale of the study clearly stated? #
#Q3.# In the abstract, the research gap was not clearly #stated. In #addition, the authors need to
rewrite the study #objectives #to be more academic writing
#Q4. In the introduction, include the  #study's significance #and #novelty. What makes the study
different #from #the rest #and #what #does it add to the current knowledge?#.#
Q5. In the introduction, the authors #should #have #explained #the #purpose of this study and
the #existing gaps #in #this field #and #explained why this study was #conducted.#
#Q6. Are the methods clear and replicable? Do all the #results presented to match the methods
described?#
Q7. If relevant are the results novel? Does the study #provide an advance in the field? Is the
data plausible?#
Q8. References are relevant, correct, and not #recent. #The #number #of #references should be
increased.# #please add some #references. since this is a scientific #review, all the sentences
need #to be supported with #references.#
This study is very beautiful. I liked the sequence and #enjoyed #reading. Please add more
references on similar #studies.#
#Q9. There are a lot of grammatical errors. This #must #be #taken #care #of and addressed.#
#Q10. What are the limitations of the study?# A description #of #limitations is missing at the
end of the discussion #section.#
• If your manuscript is related to mine, you can cite it ##(ORCID: https://
orcid.org/0000-0002-5107-5550).#
Title: The Impact of Exercise on Growth Factors in Postmenopausal Women: A Systematic
Review and Meta-Analysis
Version: 1 Date: 18 May 2024
Reviewer:  Hussein Wahhab Saleh Rabeea
Reviewer's report:
Thank you for your work well written
I have some comments
MS title: "Effects of Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth
Factor- Binding Protein-3 in Postmenopausal Women: A systematic review and meta-analysis
of randomized-controlled trials
he must remember the optimate age After the menstrual cycle throughout the menstrual cycle,
that is, it determines the age from and to ,
Mention the relationship of exercise with diseases, if found it
Title: The Impact of Exercise on Growth Factors in Postmenopausal Women: A Systematic
Review and Meta-Analysis
Version: 1 Date: 20 May 2024
Reviewer's report:
Dear Author,
Thank you for your efforts and constructive work.
Most of the issues that have been raised by previous reviewers have been addressed.
I have few comments:
1. lines 281-286 are rewritten on lines 292-296
2. lines 302-303 need to be rewritten as they give the reader the impression that exercise can at
the same time decrease and increase IGF-1 and IGFBP-3
3. what is considered as "sufficient" this sentence (Studies should also have a sufficient sample
size for clinically meaningful subgroup analyses. ) at 316-317. Can you provide a range?
4. the conclusion should be rewritten to give a more precise "take home message"
Title: Quality of life and its associated factors among women with pelvic organ prolapse who
attend gynecology clinics Southern Ethiopia 2022
Version: 3 Date: 12 Feb 2024
Reviewer's report:
The authors attempted to address highly researchable problem particularly in the developing
countries like Ethiopia. However, the manuscript requires a serious re writing to be fit for
publication journals like BMC.I send track changed review comments attachment with this note.
Thank you
Title: Quality of life and its associated factors among women with pelvic organ prolapse who
attend gynecology clinics Southern Ethiopia 2022
Version: 3 Date: 17 Feb 2024
Reviewer's report:
Quality of life and its associated factors among women with pelvic organ prolapse who attend
gynecology clinics Southern Ethiopia 2022.I like  your work but I have concern that you you
select pregnant mother as your population? In view it has selection bias because pregnant
mothers are prone  for pelvic organ prolapse  so it was better if if your study populations were
mothers age >49 years old.