JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Title: Does Neoadjuvant Chemotherapy Reduce Surgical Complexity in Patients with
Advanced-Stage Epithelial Ovarian Cancer?
Version: 2 Date: 14 Jun 2024
Reviewer's report:
I read with great interest the manuscript, which falls within the aim of this Journal and offers
a high-quality overview of the topic.
Although the manuscript can be considered already of high quality, I would suggest taking into
account the following minor recommendations:
- I suggest another language revision round to correct a few typos and improve readability.
- Inclusion/exclusion criteria should be better clarified by extending their description.
-What are the implications of these findings for clinical practice and/or further research? It is
important to report the results obtained by the authors in the context of clinical practice and to
adequately highlight what contribution this study adds to the existing literature on the topic and
future study perspectives.
- Discussions can be expanded and improved by citing relevant articles about surgical skills
frequently applied during cytoreductive surgery (I suggest authors to read and insert in references
the following article PMID: 32779050 and PMID: 32036457).
- The authors have not adequately highlighted the strengths and limitations of their study. It
would be better to explain these points.
Title: Title: Does Neoadjuvant Chemotherapy Reduce Surgical Complexity in Patients with
Advanced-Stage Epithelial Ovarian Cancer?
Version: 2 Date: 17 Jun 2024
Reviewer:  Vittorio Agrifoglio
Reviewer's report:
I read with great interest the Manuscript , which falls within the aim of this Journal.
In my honest opinion, the topic is interesting enough to attract the readers’ attention.
Methodology is accurate and conclusions are supported by the data analysis. Nevertheless,
authors should clarify some point and improve the discussion citing relevant and novel key
articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be further revised by a native English speaker
- Authors have simply reported the p values. In order to better understand the obtained results,
I suggest reporting not only the p values, but also the corresponding confidence intervals.
- What are the actual clinical implications of this study? it is important to report the results
obtained by the authors in the context of clinical practice and to adequately highlight what
contribution this study adds to the literature already existing on the topic and to future study
perspectives
- Does this manuscript conform the Enhancing the QUAlity and Transparency Of health
Research (EQUATOR) network guidelines? It would be mandatory to declare about this element
Title: Title: Does Neoadjuvant Chemotherapy Reduce Surgical Complexity in Patients with
Advanced-Stage Epithelial Ovarian Cancer?
Version: 2 Date: 20 Jun 2024
Reviewer:  Ali Mansoor AlAmeri
Reviewer's report:
Dear Author(S)
You have done great job in investigating the effectiveness of NACT in reducing complication in
stage 3-4 ovarian ca. One note is to decide certain exclusion criteria that might interfere with the
study finding. Comparison of finding with a control group would further reenforce the results.
All the best for success.
Ali Mansoor
Title: Title: Does Neoadjuvant Chemotherapy Reduce Surgical Complexity in Patients with
Advanced-Stage Epithelial Ovarian Cancer?
Version: 2 Date: 20 Jun 2024
Reviewer's report:
Thank you for the opportunity to review this interesting article.
Please, find attached my suggestions to improve the quality of this work.
- The whole text should be corrected by a native English speaker to make the work clearer and
more readable.
- The methods should be improved by clarifying the criteria used for patients.
- I find it interesting to reference the new treatment strategies currently in use for the treatment
of Advanced Epithelial Ovarian Cancer (see: PMID: 37314974).
- I also suggest authors  to better organize the discussion section following this ideal structure:
main findings of the study, strengths and limitations of the study, implications and comparison
with literature and future directions.
Title: Title: Does Neoadjuvant Chemotherapy Reduce Surgical Complexity in Patients with
Advanced-Stage Epithelial Ovarian Cancer?
Version: 4 Date: 08 Jul 2024
Reviewer's report:
Thank you for going through the manuscript and the reviewers' points
Honestly, the authors have responded satisfactorily to the reviewers’ criticisms.
The manuscript is well written and falls within the aim of this Journal.
Title: Effect of Dairy Products Fortified with Vitamin D3 on Restless Legs Syndrome in Women
with Premenstrual Syndrome, Abdominal Obesity and Vitamin D Deficiency: A Pilot Study
Version: 2 Date: 26 Nov 2023
Reviewer's report:
In fact, the literature is not  consistent in affirming vitamin D deficiency in RLS or the
amelioration of RLS symptoms with vitamin D therapy, and this is why the results could be of
interest for the scientific community.
However, there are several issues which need to be addressed in order to qualify for publication,
especially such as:
1) inclusion and exclusion criteria are unclear - was the use of any medications checked only
by a questionnaire or checked in the medical records?  was the use of contraceptives checked,
as they were mentioned in the introduction?
2) was RLS diagnosed before or it was de novo only based on the questionnaire?
3) was the consumption of either milk or jogurt checked on daily basis to ensure the consumption
(in both groups!) and the consumption of the vitamin D supplementation?
4) what about the diet? was it checked at the enrollment time and at the end of the trial in order
to compare the overall consumption of the vitamin D?
5) statistical analysis is unclear, what only t-test used as more than two groups were compared
based on PSST score??
6) Table 3, 4 and 5 - are those mean plus SD or SEM values??
7) Figure 3 - "vitamin D can increase the serum levels of vitamin D" - should rather be rephrased,
for example, " vitamin D-fortified milk products can sufficiently increase vitamin D serum
levels"
Title: Effect of Dairy Products Fortified with Vitamin D3 on Restless Legs Syndrome in Women
with Premenstrual Syndrome, Abdominal Obesity and Vitamin D Deficiency: A Pilot Study
Version: 2 Date: 14 Dec 2023
Reviewer's report:
article title: Effect of Dairy Products Fortified with Vitamin D3 on Restless Legs Syndrome in
Women with Premenstrual Syndrome and Vitamin D Deficiency: A pilot study
this article is well organized and the subject of research is interesting,
In the title part, it is better to mention the characteristics of obesity, the abstract of the article
is well written, but in the findings part, the results should be reported, and the conclusion can
also include practical conclusions.
introduction  is clearly written but its better to explain the complication of RLS AND PMS, it
seems that  the correlation between some paragraphs is missed after second paragraph and its
better to explain some alternative therapeutic  such as vitamins . It would be helpful to add some
explanations regarding obesity and its association with restless legs syndrome and premenstrual
syndrome.
In the methodology section, the reliability and validity of the questionnaires should be
mentioned, and according to the selection of respondents from among the staffs and their
relatives, the possibility of contamination and information exchange and its control method
should be explained. Anthropometric characteristics and how to measure them should be
described in detail.
In the findings section, it seems that merging the tables can give better coherence to the findings.
In the discussion section, in relation to the possible mechanisms of the observed phenomena,
more explanations should be given with an emphasis on obesity, and finally, in the conclusion
section, the application of the findings should be further expanded.
Best of luck
Title: Effect of Dairy Products Fortified with Vitamin D3 on Restless Legs Syndrome in Women
with Premenstrual Syndrome, Abdominal Obesity and Vitamin D Deficiency: A Pilot Study
Version: 4 Date: 19 Feb 2024
Reviewer's report:
Thank you very much for answering to all raised points.
However, I still have two concerns:
- t-test cannot be used to compare more than two groups - in such cases ANOVA should be used!
– the manuscript needs English editing - especially the newly incorporated fragments - there is
inconsistency in using past and present tense, and in some places the infinitive of a sentence
instead of a full sentence were used.
Title: Association of Caesarean Scar Defect with Risk of Abnormal Uterine Bleeding: Results
from Meta-Analysis
Version: 0 Date: 10 Dec 2023
Reviewer:  Mario Palumbo
Reviewer's report:
I was pleased to review this paper.
The methodology used by the Authors is appropriate for the purpose of the article description.
The English language is fluid and well understood, nevertheless, except in some places that I
will select you later, but overall, a minor revision is needed.
o Regarding the introduction you can add these works to deepen the topic DOI:
10.1155/2018/6486407;  10.1080/01443615.2017.1363171.
o 182-214 You can get better by using more fluid English;
o Better explains weaknesses and strengths of work;
o In your opinion, explain what contribution this paper can make to the scientific community;
o you should deepen the discussion by rearranging the speech;
o Try to improve the job design compared to the division you made of paragraphs.
o  Increase the references with current major works;
Title: Association of Caesarean Scar Defect with Risk of Abnormal Uterine Bleeding: Results
from Meta-Analysis
Version: 0 Date: 25 Dec 2023
Reviewer's report:
I read with great interest the Manuscript titled “Association of cesarean scar defect with risk
of abnormal uterine bleeding: results from meta-analysis”  which falls within the aim of BMC
Women's Health.
In my honest opinion, the topic is interesting enough to attract the readers’ attention.
Methodology is accurate and conclusions are supported by the data analysis. Nevertheless,
authors should clarify some point and improve the discussion citing relevant and novel key
articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be majorly  revised by a native English speaker to correct several non-
english constructs.
- There is a recent meta-analysis on the topic  (see and cite PMID: 35985862) by the FIGO
working group on menstrual disorders. Authors should comment on differences and explain why
another meta-analysis was needed. Otherwise there is no need for another update on the topic
in such a little amount of time.
- Discussion should be improved by analyzing the impact of a cesarean scar defect and other
uterine surgery on reproductive outcomes, which as important as the presence of AUB (see and
cite PMID: 34414568 and PMID: 33100090).
- Was the meta-analysis registered in PROSPERO? It is mandatory to prospectively register the
protocol of any systematic review to guarantee transparency.
Title: Effects of Metformin on CIMT and FMD in PCOS Patients: a Systematic Review and
Meta-analysis
Version: 1 Date: 20 Jun 2024
Reviewer:  Ahmed Taher Masoud
Reviewer's report:
The manuscript has several major issues:
1.  The use of the analysis method is not appropriate. RevMan uses a test that compares
independent groups and cannot be used to compared baseline versus post-interventions.
2. The analysis is severely heterogeneous making the evidence non-reliable.
3. No attempts to solve the heterogeneity were made, values of I2 over 90% greatly doubt the
interpretation of the results
4. Abstract methods section lacks more details.
5. PRISMA checklist was not provided.
Title: Risk prediction model of uterine corpus endometrial carcinoma based on immune-related
genes
Version: 3 Date: 04 May 2024
Reviewer's report:
In this manuscript, the authors constructed a prognostic risk prediction model based on the
important role of immune-related genes in the progression of endometrial cancer uterine corpus
endometrial carcinoma (UCEC) and long-term prognosis of patients. Thirty-three immune-
related genes associated with the prognosis of UCEC were screened by clustering analysis,
immune score and immune cell ratio analysis.
As highlighted by the authors, while numerous studies have focused on developing similar
models, none have specifically delved into the realm of endometrial cancer modeling using
immune scores as a guiding framework. Hence, this paper represents a noteworthy addition to
the existing research landscape.
However, there are some linguistic nuances and unclear citations that need to be addressed. Take
an example, the discussion section contains a statement: "Many disease studies have found that
the prediction of tumors and cancer can be realized using a risk prediction model. For example,
prostate cancer is a risk model[26]." This phrase is semantically ambiguous and may lead to
confusion. We suggest the authors rephrase and reorganize this part to convey their ideas more
precisely.
Furthermore, in terms of literature citations, the manuscript mentions: "It has been used
in pancreatic cancer, breast cancer, cervical cancer, and other diseases [27-29]." However,
upon closer examination, the titles of these citations (27-29) primarily focus on endometrial
carcinoma. Therefore, we recommend that the authors double-check these citations to ensure
accuracy and relevance.
Lastly, regarding image presentation, all figures in this paper require enhancements to boost
readability and aesthetics. Specifically, Figure 2 is partially obscured due to its size, and we
recommend that the authors modify it to ensure the comprehensiveness and accuracy of the
presented information.
Title: Risk prediction model of uterine corpus endometrial carcinoma based on immune-related
genes
Version: 3 Date: 08 May 2024
Reviewer's report:
I read with great interest the Manuscript titled " Risk prediction model of uterine corpus
endometrial carcinoma based on immune-related genes" which falls within the aim of the
Journal.
Although the manuscript can be considered already of good quality, I would suggest following
recommendations:
- I suggest a round of language revision, in order to correct few typos and improve readability.
- In recent years the classification of endometrial cancer has evolved significantly. Considering
results and topics of this study, I suggest that authors add references about recent evidence and
novel insights of endometrial cancers. I would be glad if the authors discuss this important
point, referring to PMID: 36983243 and Ottavia D'Oria,  Andrea Giannini,  Aris Raad Besharat,
Donatella Caserta. Management of Endometrial Cancer: Molecular Identikit and Tailored
Therapeutic Approach. Clin. Exp. Obstet. Gynecol. 2023, 50(10), 210.https://doi.org/10.31083/
j.ceog5010210.
Because of these reasons, the article should be revised and completed. Considered all these
points, I think it could be of interest to the readers and, in my opinion, it deserves the priority
to be published after minor revisions.
Title: Risk prediction model of uterine corpus endometrial carcinoma based on immune-related
genes
Version: 5 Date: 12 Jun 2024
Reviewer's report:
Dear Authors,
I am writing on behalf of the review panel to extend our heartfelt appreciation for your diligent
revisions. Your commitment to excellence and meticulous attention to detail have truly shone
through in the latest iteration of your manuscript. The enhancements made have successfully
elevated the work, aligning it with our publication standards in terms of depth, breadth, clarity,
accuracy, and comprehensive referencing. Your dedication has transformed the piece into a
valuable contribution to the academic discourse.
Title: The influence of Assisted Reproductive Technologies-related stressors and social support
on perceived stress and depression
Version: 2 Date: 23 Mar 2024
Reviewer's report:
BMC Women’s Health
Review of “The influence of Assisted Reproductive Technologies-related stressors and social
support on perceived stress and depression”
This article leverages data collected from an online survey to examine whether and how
perceived stress and depression are associated with the infertility and ART process, as well
as ART-related stressors, and support from partner and provider. The authors find positive
associations between several stressors (e.g., perceived social stigma, physical and time demands
of ART procedures) and mental health. They also demonstrate a significant association between
partner support and perceived stress. The analysis is thoughtful, and the results are well
organized and presented. However, I have several concerns about the manuscript, as detailed
below:
Major:
• The presentation of qualitative data appears unconventional to me. The selective use of quotes
in the discussion section requires further justification. Have you considered conducting a mixed-
methods study given the abundant qualitative information available? It would enhance the clarity
of the study if the authors could provide additional context and description of their qualitative
data, particularly since it was heavily relied upon in the discussion section.
• Could the authors provide clarification on their decision to analyze each stressor separately
rather than integrating them into a single model or combining them into one measure? As they
mentioned, “in reality, ART-related stressors often co-occur and exacerbate one another.” It
would be beneficial if the authors could provide a correlation table illustrating the relationships
among all the stressors.
• The authors framed “social support as a buffer of ART-related stress”, leading me to anticipate
an examination of the moderating effects of partner and provider support (i.e., social support
moderating the associations between ART-related stressors and mental health). However, the
study did not conduct moderation analyses. It is crucial for the authors to clarify their intended
meaning of “buffer” in this context.
• “Individuals in this group also reported that speaking to their provider was significantly less
helpful in reducing their stress.” Could the authors provide some insights on this somewhat
unexpected result?
• The alleviating effect of counseling psychosocial was not directly examined in the current
study; therefore, it should be removed from the conclusion. The recommendation appears to be
an extrapolation of the current findings. Instead, the authors can suggest more research effort
and policy attention in that direction.
Minor:
• Was the entire sample comprised of cisgender women? Additionally, is there data available
regarding the gender of their partners?
Title: The influence of Assisted Reproductive Technologies-related stressors and social support
on perceived stress and depression
Version: 4 Date: 30 May 2024
Reviewer:  Deepshikha Ray
Reviewer's report:
This is a very relevant study in today's world.
The sample size is also large.
Appropriate statistics have been done. But there is a lacuna in the reporting of the details of
statistical analysis in the main manuscript.
Also, there is error in the reporting of "hypothesis".
Discussion is well written.
Title: The influence of Assisted Reproductive Technologies-related stressors and social support
on perceived stress and depression
Version: 4 Date: 22 Jun 2024
Reviewer's report:
I was not the original reviewer of the paper, but reading through the prior comments and the
changes made, I think the authors have significantly improved on their work. This is such
an important topic-- it seems to be common knowledge that going through ART is intensely
stressful, but there are few systematic studies that outline these emotions (or rather, the causes of
these emotions) so clearly.  This article is a critical contribution to the literature.  I recommend no
changes. However, the authors might want to think through how gender shapes  stress. Arguably,
this is not a focus, but you still might want to highlight that there would be differences (is
your next article on that, for example). And, second, please consider race/ ethnicity, including
religious beliefs. My last two points are not about short-comings, but about what you might want
to flag in the concluding paragraph as avenues for further research.
Title: Antibiotics improve reproductive outcomes after frozen-thaw embryo transfer for chronic
endometritis treatment, especially in those with repeated implantation failure
Version: 1 Date: 29 Feb 2024
Reviewer:  Yigit Cakiroglu
Reviewer's report:
General comments:
The manuscript has been processed in accordance with the author guidelines of the journal.
The manuscript proposes information about a very critical relationship in between antibiotics
treatment and chronic endometritis in patients with repeated implantation failure.
Abstract:
The abstract accurately describes the short-summarized content of the article.
Key words are adequate in quality and number.
Introduction:
The rationale of chronic endometritis, antibiotic treatments, and the relationship with repeated
implantation failure have been described in the introduction section.
Materials and Methods
The materials and method section contains the type of the article, study population, data analysis
and statistical methods employed.
- Would the authors please define whether they have re-biopsied after antibiotic treatment to
figure out if the patients still have the CE?
Results
The result section contains findings and observations in regards of the findings.
Discussion
The discussion section states the importance of the findings.
References:
The references section contains appropriate and reasonable number of references
Figures:
Figures are so representative.
Title: Antibiotics improve reproductive outcomes after frozen-thaw embryo transfer for chronic
endometritis treatment, especially in those with repeated implantation failure
Version: 1 Date: 29 Mar 2024
Reviewer:  Ashish Kale
Reviewer's report:
It's known fact that CE has less implantation rate as well as it's can only be done by doing biopsy
without hysteroscopy as well as 3D usg to know silent features of it
Title: Antibiotics improve reproductive outcomes after frozen-thaw embryo transfer for chronic
endometritis treatment, especially in those with repeated implantation failure
Version: 2 Date: 08 May 2024
Reviewer's report:
The number of cases is very high and very interesting among the cohort studies on CE reported
so far. In particular, a multivariate analysis of background factors for CE was conducted, and
the large number of cases was felt to be very important in examining factors associated with CE.
One point that needs to be considered for revision is that the association between RIF and CE
is examined using the Kaplan-Meier curve, but data on the extent to which RIF was actually
included in the CE and non-CE groups is missing. It is also expected that the number of ET is
related to the number of ET as a background factor for CE, but why was this not included in
the multivariate analysis?
While the number of cases verifying the background of CE is sufficiently large, the number
of patients verifying for ET is 366, which is not very large. In particular, the number of cases
verifying the pregnancy outcomes for the presence of CE on hysteroscopy and for CE on
histological diagnosis is 133, and it is questionable whether verification with this number of
cases in a retrospective study would be of significance.
Furthermore, the selection criteria for antibiotic treatment in cases with negative CE on histology
but positive CE on hysteroscopy have not been established and it is mentioned that it was on a
case-by-case situation, which means that bias cannot be ruled out and the data is not credible
due to the small number of cases.
Although the content is very interesting, the impression is that the validation of pregnancy
outcomes in ET cycles should be focused only on those with a large number of cases.