Reviewer ’s report  
Title: Patterns of missing data in the use of the Endom etriosis Symptom Diary  
 
Version: 0 Date: 21 Jun 2017  
 
Reviewer: C. Matthew Peterson  
 
Reviewer's report:  
BMWH -D-17-0021  
Patterns of missing data in the use of the Endometriosis Symptom Diary  
 
This is a well written post -hoc summary of missing data from the endometriosis symptom diary 
of the Validation Study for Endometriosis Patient Reported Outcomes (VALEPRO) study 
(clinicaltrials.gov identifier NCT01643122). A Likert scale is used to assess the three main 
symptoms of endometriosis (pelvic pain, dysmenorrhoea and dyspareunia) at their worst, in the 
preceding 24 h. The data confirm high compliance with a minimum of missing data. This version 
of the manuscript is clear, concise and reports the d ata needed to comply with standards required 
to validate the tool's accuracy. I have no further recommendations.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the necessary controls?  
If not, please  specify which controls are required in your comments to the authors.  
Yes 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
Not relevant to this manuscript  
Quality of written Engli sh 
Please indicate the quality of language in the manuscript:  
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years received reimbursement s, fees, funding, or salary from an  
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you currently applying for any patents  relating to the content of the 
manuscript?  
4. Have you received reimbursements,  fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
5. Do you have any other financial competing interests?  
6. Do you have any non -financial competing interests in relation to this  paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, p lease give details below.  
 
I declare that I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my name d report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I und erstand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal