Reviewer ’s report  
 
Title: Is there a correlation between inflammatory markers and coagulation parameters in 
women with advanced ovarian endometriosis?  
 
Version: 0 Date: 30 Jun 2018  
 
Reviewer: Justyna Sikora  
 
Reviewer's report:  
 
The aim of study o f Ding et al. was to to investigate the role of the abnormal coagulation in 
the pathology of endometriosis by testing coagulation indicators in women with or without 
endometriosis and exploring its relationship with inflammation. The study is very interest ing, 
especially that the results of this study may be practical use. I have only a few questions:  
 
1. The "Introduction" and "Discussion" parts are too long. Some information, too detailed, is 
unnecessary.  
 
2. In "Materials and Methods" please add characte ristic of control group. What was the 
reason for laparoscopic surgery? Could other reasons have influenced the change of the 
peripheral blood environment?  
 
3.     How you checked the phase of the menstrual cycle?  
 
4.     Have the presence of anti -phospholipi d antibodies been checked in patients with 
endometriosis? These antibodies can affect hemostasis.  
 
5.     Results in tables are not redable.  
 
6.     Wht was nubmers of white blood cells and populations of patients?  
 
7. Why did you choose only women with a dvanced endometriosis? The largest inflammatory 
changes are in women with early -stage disease.  
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comment s to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical rev iew?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from 
an organisation that may in any way gain or lose financial ly from the publication of 
this manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financi ally from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to the content of 
the manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organiz ation that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of th e above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
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