Title: The minimally invasive resection of port-site metastasis of ovarian cancer after
laparoscopy with cutaneous integrity: a case report and literature review
Version: 2 Date: 12 Aug 2024
Reviewer:  Antonio Bandala-Jacques
Reviewer's report:
Dear authors -  I have reviewed your manuscript and offer the following comments-
BACKGROUND
A) Your first sentence "Ovarian cancer is a common type of cancer that affects the female
reproductive system. "
This statement is false. If you mean incidence, then corpus uteri is far more common.
Please revise this statement
https://gco.iarc.who.int/media/globocan/factsheets/populations/900-world-fact-sheet.pdf
B) In the phrase, "Laparoscopy, a minimally invasive method, is used for both diagnosing and
treating early ovarian cancer", this implies that laparoscopy is the preferred and/or only method
to surgically treat ovarian cancer. I suggest you revise this sentence.
C) Your sentence "also benefit from a less traumatic surgery and a
potentially faster recovery" is identical to the conclusion found in the paper you cite., I suggest
you re-phrase using your own words
D) The phrase "Wound healing disorders was reported in the patients with port-site metastasis
[2]."  is not grammatically correct. Please revise
E) In "The challenges in port-site metastasis resection we need to address include completely
removing the lesion, promoting fast wound healing, and preserving the abdominal wall's
integrity. " you suddenly speak in the first person. You should reserve this for referring to thins
specifically addressed by you, the authors, regarding the case, as earlier in the manuscript you
have used the third person to state facts
F)  In, "Till now, there is no report specified about the minimally resection of the port site
resection after gynecological malignancy" Please revise this phrase for language and try to avoid
colloquialisms. Furthermore, this sentence is hard to understand. There are no reports regarding
the minimally resection what?
CASE PRESENTATION
G)  Why was laparoscopy used in a stage IIA patient? The guides mention that laparoscopy
may be considered in early-stage ovarian cancer where fertility preservation is a goal, or in
cases where the disease is localized and can be completely resected with a minimally invasive
approach.
H) Please briefly describe the initial management of the patient. Was cytoreduction optimal?
I) Was the abdominal mass the reason for consultation, or was this detected during a routine
follow-up?
J) You mention" Clinical examination, color ultrasound, and enhanced computed tomography
(CT) confirmed the findings (Figure1a-1d), with no further evidence of metastasis elsewhere."
Was CA-125 elevated? you only provide CA-125 levels one mont post-resection
DISCUSSION AND CONCLUSION
K) Please revise the discussion for language and grammar
L) Your discussion fails to put your case in the context of available literature. Have other authors
resected port-site metastases with laparoscopy? What were the outcomes?  You provide a lot of
suggestions on changes to clinical practice, but this can be overstated by basing it on a single case
OTHER
M) Your figures include arrows. Please specify what they are pointing to within the figure
legends