Reviewer ’s report  
 
Title: Radiation therapy for vaginal cancer in complete uterine prolapse: a case report  
 
Version: 0 Date: 13 Mar 2019  
 
Reviewer: Diama Bhadra Vale  
 
Reviewer's report:  
 
Dear authors,  
 
Thanks for the opportunity to review your study.  
This is a relevant work that adds knowledge to medical science and may be of value at clinical 
practice. My comments intend to improve your work.  
1) I wonder if the manuscript would be improved with more cl inical information about the 
woman. It could be included for example BMI, race, screening history, smoking status, 
etc. 
 
2) Was concurrent chemotherapy offered? If not, please explain.  
 
3) I would strongly suggest authors to build a table with the technical information of the 
treatment per session. Example: week one first treatment day - GVT, dose, accumulation 
dose, etc… That would give a clearer picture about technical aspects to be reproduced.  
 
4) The authors should address the main important limitation of  the case - the short follow -up 
period. It is not possible to conclude that the therapy was "effective" as they claimed with 
such a short time follow -up. 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to th e authors.  
 
No 
 
  
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this  manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied f or patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report t o the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under an Open Access Creative C ommons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the op en peer review policy of the journal