Reviewer ’s report  
 
Title: Prevalence and severity of menopause symptoms among perimenopausal and 
postmenopausal women aged 30 -49 years in Gulele sub -city of Addi s Ababa, Ethiopia  
 
Version: 1 Date: 20 Apr 20 17 
 
Reviewer: Nese Yuksel  
 
Reviewer's report:  
 
I believe the authors have done a great job with revising the manuscript and responding to the 
reviewers comments.  
I have very few suggestions,  just a couple of minor revisions:  
1) Discussion: Page 15, line 60 - would suggest changing m ore broadly to "using hormone 
therapy (HT) or non -hormonal options (such as venlafaxine, paroxetine, etc)".  Can reference 
the 2016 IMS guidelines (Baber et al. 2016 IMS Recommendations on women's midlife 
health and menopausal hormone therapy. Climacteric; 19:2:109 -150) instead of the ones 
currently referenced.  These guidelines provide a good review on options.  As well, though 
there may have been a study on folic acid (that you referenced), this is not commonly used 
for treatment of vasomotor symptoms.  Su ggest looking at the IMS reference.  
2) Limitations: it should be added that the data on HT use (or other options for menopause 
symptoms) was not captured.  Some women could have been on HT therefore may have 
affected the interpretation of the MRS (ie what if there symptoms were being managed with 
the HT)?  
3) Conclusion: spelling mistake "perimenopause"  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work inc lude the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
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