Reviewer’s report
Title: 
Neutropenic enterocolitis-induced sepsis and disseminated intravascular coagulation after
chemotherapy: A case report
Version: 
1 
Date: 
18 Jul 2020
Reviewer's report:
First, I'd like to congratulate the authors for being able to cure this critically ill patient.
Unfortunately I do not find any important new information provided in this manuscript. Neutropenic
enterocolitis has been described previously in several settings, including associated with paclitaxel and
carboplatin for ovarian cancer. Many ovarian cancer patients develop postoperative ileus but have been
treated subsequently with paclitaxel and carboplatin without problems. The authors claim that the
insertion of an ileal tube rescued the patient while providing no hard evidence supporting this.
Besides the remarks above, there are other, minor problems with this manuscript. Chemotherapy is not the
cornerstone of the treatment for endometrial cancer. It is surgery that is the cornerstone. In serous uterine
carcinoma the role of chemotherapy is of course more important, but the authors reveal that the patient
had a serous carcinoma not until in Discussion. They also fail to tell that the patient was obese not until in
Discussion. Carboplatin (as contrasted to cisplatin) is prone to cause neutropenia, although the authors
that this is not true.
Based on the above, I regret that I cannot recommend the publication of this case report.
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