Reviewer ’s report  
 
Title: Frequency and genotypes of Chlamydia trachomatis in pa tients attending the obstetrics 
and gynecology clinics in Jalisco, Mexico and correlation with sociodemog raphic, behavioral, 
and biological factors  
 
Version: 0 Date: 20 Jun 2016  
 
Reviewer: Daman Saluja  
 
Reviewer's report:  
 
With increasing anti microbial resistance, it is important that the host -pathogen interactions 
should be studied in detail.  The first step is to identify the various strains and their association 
with specific symptoms.  Work described is good and suggest s that E and F serovars are most 
frequent in the population tested.   This is in contrast to some of the other reports.   
 
As regards to associations of C. trachomatis genotypes with risk factors in the study population, I 
feel about 100 samples is too low to associate the said serotype with a specific risk factor and 
symptom.  This is rather a preliminary report in that direction and needs to done on a much 
larger cohort.  Hence it would be better if this data is expanded on higher number of chlamydia 
posit ive samples.  
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I recommend additional statistical review  
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
 
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary f rom an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has ap plied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare no competing interests  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report t o the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I agree for my report to be made available under a n Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as  confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal