Reviewer’s report
Title: 
Negative histology in cervical specimens obtained with the “see and treat”
method among women at a referral center in Rio de Janeiro, Brazil – a cross-
sectional study.
Version: 
2 
Date: 
17 Jul 2021
Reviewer: 
Edmund Ossai
Reviewer's report:
Review comments
General comments
This is a good study and the results are of relevance. However, there are some
issues that should be addressed before the manuscript could be accepted for
publication. 
1. The manuscript should be organized into distinct paragraphs.
2. The only statistical test done in the study should be reviewed including the
interpretation of the result.
Title 
Negative histology in cervical specimens obtained with the "see and treat"
method among women at a referral center in Rio de Janeiro, Brazil
Key words: Include Rio de Janeiro, Brazil
Inclusion criteria
In the abstract, age was included in the inclusion criteria. This was not part of the
inclusion criteria mentioned in the body of the manuscript. This should be
reviewed.
The pattern of referral of women in the 'see and treat' method in Brazil should be
explained.
Statistical analysis
The authors indicated that there was a binary logistic regression analysis. This
should be a multivariate analysis. There was no table showing the result of this
analysis. Also, only one variable was indicated to have been included in the
logistic regression model apart from the outcome variable. This reveals it was a
bivariate analysis. This aspect of the study should be reviewed.
First a table showing the result of this analysis should be shown. If only two
variables are included, it should be correctly stated as a bivariate analysis. 
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Declaration of competing interests
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paper?
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes