Reviewer’s report
Title: 
Factors associated with mammographic breast density among women in
Karachi Pakistan
Version: 
0 
Date: 
20 May 2021
Reviewer's report:
Thank you for the opportunity to review this manuscript, I have no COI to
disclose. 
This is an interesting study that is well written and informative. The authors
detail their methods very well, and discuss their results appropriately. 
Few suggestions:
"Women who were extremely sick" Please specify what this means. 
What do you mean by "opportunistic screening".?
Please define body mass index as BMI at first mention in text, and use BMI
consistently throughout the text. 
The authors jump between inclusion and exclusion criteria in their methods. I
suggest having all inclusion criteria mentioned first, and then having all
exclusion criteria separately.
Please cite "American College of Radiology Breast Imaging Reporting and Data
System" in the methods. 
"Analyses were restricted to patients with an available BI-RADS" Won't these
patients excluded?
"180 women". Please write out the numbers with letters when starting sentences. 
"This is higher… women in Jordon" Please remove such parts from the results,
and only include those in the discussion. The results section should only include
your data. 
This is a case-control study. The authors could consider having a table assessing
the differences in baseline characteristics between cases and controls (maybe as
a supplementary).
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes