Reviewer’s report
Title: 
Association between body mass index and fragility fracture in
postmenopausal women: a cross-sectional study using Korean National Health
and Nutrition Examination Survey 2008-2009 (KNHANES IV)
Version: 
0 
Date: 
31 Oct 2020
Reviewer's report:
The Authors investigated the relationship between body mass index (BMI) and
the risk for fragility fractures in a cohort of postmenopausal Korean women
selected from subjects who participated in the 4th National Health and Nutrition
Examination Survey (2008-2009). In their cross-sectional study, the Authors
found that obesity and underweight increased the risk for fragility fractures.
The study address a relevant topic and is well written. However some critical
issues should be discussed.
A definition of "fragility fracture" may be introduced in the methods section.
When considering vertebral fractures, the Authors record indifferently single and
multiple fractures: due to loss of height related to vertebral fractures (especially
multiple vertebral fractures), BMI could be consequently impaired. This point
should be highlighted in the discussion section.
What about fracture rate in the "overweight"? 
It is not expected to observe a higher femur BMD in underweight: how do the
Authors explain this result? Is it femur BMD associated to T-score in this group?
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Is the study design appropriate to answer the research question (including the use
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presented?
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