Reviewer’s report
Title: 
Practice Patterns  of  Adjuvant Radiotherapy in Women with Stage I to II
Endometrial Carcinoma: A Real-World  Multi-Institutional  Analysis  in  China
Version: 
1 
Date: 
20 Mar 2023
Reviewer's report:
Firstly, thank you to invite me to review this manuscript. This study reported
retrospectively pattern of adjuvant radiotherapy in endometrial cancer. 
1,227
patients were enrolled and showed the postoperative VBT has increased
remarkably in all risk groups. This study is interesting to report the results in the
big sample size. The comments are as the followings
* Please give details of chemotherapy in
o How many protocols of chemotherapy involved in this study?
o How many cycles of chemotherapy?
o How many patients in each group received chemotherapy?
* Please confirm that the CTV of VBT in
o The expansion of CTV, did author exclude the surrounding OARs?
o What is the median vaginal length in author study?
* Because of variety of schedule of brachytherapy, please give details of overall
treatment time in EBRT plus VBT and VBT alone
* No report of clinical outcomes of this study. It will be nice to report the clinical
outcomes, conclusively. 
* In table 2, please explain why the author have adjuvant radiotherapy in the
low-risk group. Normally, in international guidelines, observation is the standard.
* In table 1, some details may be needed to show such as, involvement of cervix,
numbers of LVSI, and so on. It will be interesting to detail about the numbers of
patients in each stage or in each group who received adjuvant chemotherapy.
Declaration of competing interests
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes
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No