JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 2 Date: 04 Apr 2025
Reviewer:  Adebayo Adekunle Akadri
Reviewer's report:
The manuscript is relatively well written.
There are few  rearrangement that need to be done
My main issue with the manuscript is  the scoring system  of the questionnaire which I find
difficult to understand .
The authors should make this clear.
-Number of questions
-Score per question
-Maximum score
-Cut-off used for the variable of interest e.g good knowledge
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 2 Date: 05 Apr 2025
Reviewer:  Shazia Saaqib
Reviewer's report:
Dear authors,I appreciate the hard work you perfomed in such a short time and considered every
aspect of your survey with full details.But i have a few concerns about your study
1-title:You mentioned  management in title of survey  while I could not find it in study method
and results.
2-Introduction mentions a half hearted management by FSH  but again in study,you did not
perform management survey.Your focus is survey of investigations and diagnosis only.
3-You have surveyed parameical staff for investigations which is out of their scope in most
parts of the world and could raise concerns about validity of the study.Investigations are costly
and Treatment needs USG guided monitoring to avoid complications.Therefore I advise you to
include  responses only from properly qualified staff with a medical degree and above inbefore
publication.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 3 Date: 23 Apr 2025
Reviewer:  Shazia Saaqib
Reviewer's report:
Dear Authors,
Thank you for choosing such an important and relevant topic for your study. The abstract is clear
and gives a good overview of the subject. I especially liked the introduction, which includes all
the necessary background and makes the study interesting to read.
The main issue in the study—the differences between educational level of categories—was
explained well in your response letter, and your results support this. However, I would like to
point out a few small errors that might confuse readers or make the study seem less accurate
than it is.
• In line 46, you mention that FSH levels are most commonly used to diagnose PCO. As far
as I know, FSH levels alone are not used for diagnosis. PCO is usually diagnosed by a raised
LH/FSH ratio, where LH is higher (tested on the 2nd or 3rd day of the menstrual cycle). Please
use "LH/FSH ratio" instead of FSH levels here, and also correct this in lines 190, 230, and any
other similar places.
• In line 174, under the supplementary material about attitude, please fix the numbering (change
10 to 8).
• In line 184, the supplementary material could be made clearer by putting numbers and
percentages in the same column—for example, like this: a (b%). Also, try to remove any
unnecessary empty rows.
• In lines 203–207, the description of the results would be stronger if you added more detail.
Please mention the categories such as gender, education, experience, and profession, along with
their subcategories and which ones performed better. For example: “In the gender category, there
were male and female participants; male participants scored slightly higher, but the difference
was not significant.”
With these small corrections and removal of typos, I believe the study is suitable for publication.
Best regards,
Reviewer Shazia Saaqib
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 3 Date: 25 Apr 2025
Reviewer's report:
The manuscript is written in a clear and comprehensible manner, and the tables are presented in
a straightforward and interpretable format. However, I suggest that the authors briefly mention
in the Introduction that supportive inflammatory markers have also gained attention in recent
years in the diagnosis of PCOS. The article with PMID: 36599370 may provide useful insights
in this regard.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 3 Date: 02 May 2025
Reviewer:  Fullaila Onozare Aliyu
Reviewer's report:
Dear Authors, thank you for making substantial improvements in your work, However there are
still certain areas that needs improvement
1. You have been told severally to Re-do all your tables using table in microsoft word rather
than importing your tables
2. Abstract- Rephrase your results starting from knowledge, attitude and practice rather than
knowledge, practice and attitude
3. was the internal consistency validated after receiving responses from your 210 respondents?
4. other comments are embedded in the work
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 3 Date: 03 May 2025
Reviewer:  Adebayo Adekunle Akadri
Reviewer's report:
The authors have attended to the queries.
Just a few  minor concerns:
Supplementary file 3:
The authors should put the label  percentage or % in the appropriate columns for Male and
female.
The authors should also consider replacing the term "supplementary file" with "table" for all the
tables placed within the manuscript.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 4 Date: 22 May 2025
Reviewer:  Adebayo Adekunle Akadri
Reviewer's report:
There has been great improvements in the manuscript.
However, there appears to be a typographical error in the statement in line 346-347.
kindly correct this.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 4 Date: 26 May 2025
Reviewer:  Shazia Saaqib
Reviewer's report:
Congratulations on submission of a thorough report about KAP of PCO in your region. I have
just one objection.GFSH value alone has no worth in diagnosis of PCO. it is LH/FSH ratio the
participants may be referring to. You have corrected it in manuscript but  in Abstract section
results, the same terminology persists. Please correct it.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 4 Date: 01 Jun 2025
Reviewer:  Fullaila Onozare Aliyu
Reviewer's report:
Dear Authors, Thank you for your relentless efforts in incorporating the suggestions and inputs
to your work. There a just a few typo errors left and a few suggesting embedded in your work.
Good work to you all.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 5 Date: 11 Jun 2025
Reviewer:  Shazia Saaqib
Reviewer's report:
The writing style has much improved in clarity. The diagnosis of PCO is usually not based on
FSH levels alone, but the ratio of LH to FSH which is raised.But you got reponse as FSH alone
which might have been correlated with clinical and imaging findings.Rest of the study is already
correct so I approve the study as such .
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 5 Date: 12 Jun 2025
Reviewer:  Adebayo Adekunle Akadri
Reviewer's report:
The authors have addressed most of the issues raised by the reviewers.
However, I am concerned about this new addition in line 136-138.
"The sample size was calculated using a 50% population proportion assumption yielding a target
sample size of 299 participants. A total of 210 participants were enrolled in the survey via a
convenient sampling technique."
This gives the impression that the study is underpowered.  This should be addressed.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 5 Date: 15 Jun 2025
Reviewer:  Fullaila Onozare Aliyu
Reviewer's report:
Comments to Authors
1. Rather than referencing year of study, reference the Author's name only and year of study
in parenthesis if only one Author or addition of  'et al' if more than one Author then year in
parenthesis (Line 339 and 364).
2. Your beginning statement in Line 318 and 322  is indicating that it was due to your work a
study was conducted in GWU and Germany. That is not the case. Better to use ''similar to....''
to avoid misinterpretation
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 6 Date: 26 Jun 2025
Reviewer:  Fullaila Onozare Aliyu
Reviewer's report:
Dear Authors, Good work for your persistent effort in improving your manuscript. However, i
found inconsistencies in your references and i couldn't find reference [10] online
1. Reference [10] can't be found online, either provide another reference or provide the current
reference DOI
2. Kindly work on your references, they are a number of inconsistencies. If you are using
Vancouver make all referencing as Vancouver.
3. Other recommendations are embedded in the work.
Title: Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among
Health Care Providers in Addis Ababa, Ethiopia
Version: 6 Date: 30 Jun 2025
Reviewer:  Shazia Saaqib
Reviewer's report:
I congratulate you on writing a precise report of KAP in your region. I have already approved
your previous version, but this time the manuscript is even better. Just there are a few mistakes
of punctuation which you should take care of during proofreading.
. The thing I like most is your detailed and accurate presentation of results like an expert
researcher. I again approve your manuscript for publication. Best of luck!
Title: Human Papillomavirus Infection among Patients with Cervical Cancer in Cambodia
Version: 2 Date: 04 Jun 2025
Reviewer:  Michael Odida
Reviewer's report:
An interesting manuscript on an important topic. It is well written. There are some minor issues
to address as follows:
The conclusion in the abstract needs to resonate with the one at the end of the manuscript.
In the methods section, the ethical approval statement could be put at the end of the methods
section.
In the results section, the comparison of HPV prevalence with other areas need to form part
of the discussion. The results report 47 controls, yet in the methods, 56 controls were initially
selected. What happen to the others?
There is no need to put ''Statistical Analysis Author"
Title: Human Papillomavirus Infection among Patients with Cervical Cancer in Cambodia
Version: 2 Date: 20 Jun 2025
Reviewer:  Kuralay Kongrtay
Reviewer's report:
Overall, the manuscript presents the first comprehensive genotyping of HPV among cervical
cancer patients in Cambodia. This is highly relevant in perspectives of the country’s recent
HPV vaccination rollout and has both national and regional significance. However,  some minor
changes needed before publication. .Lines 70-71 "The observed prevalence of HPV-16 or -18
did not differ substantially " - statistical terminology can be used instead.
In introduction part some additional recent regional comparisons and prevalence data from
neighboring countries in Southeast Asia or overall Asian countries can be cited. (E.g., Chan CK,
Aimagambetova G, Ukybassova T, Kongrtay K, Azizan A. Human Papillomavirus Infection and
Cervical Cancer: Epidemiology, Screening, and Vaccination-Review of Current Perspectives.
J Oncol. 2019 Oct 10;2019:3257939. doi: 10.1155/2019/3257939. PMID: 31687023; PMCID:
PMC6811952.)
In Methodology part: The criteria's of inclusion and exclusion should be listed explicitly.
The heterogeneity of testing methods between case (NGS-based) and control (PCR/IHC-based)
groups can reduce comparability and should be discussed in limitations section.
Results part well written and structured. However, some clarifications should be provided in
terms of rationale for comparing only HPV-16/18/58 with global data, despite other types being
mentioned in the literature.
In summary, this is a relevant  manuscript suitable for publication given the lack of prior data
in Cambodia and its potential influence on national immunization strategies.
Title: Promoting Early Detection of Necrotizing Soft Tissue Infection of the Upper Extremity
in Patients with History of Breast Cancer: A Case Report
Version: 2 Date: 17 May 2024
Reviewer's report:
I think this is a very important topic to flag in the literature. I commend you on the accurate and
swift diagnosis and my condolences  for the unfortunate outcome.
However regarding the article I have a few issues with how it is written and presented. I have
flagged in the document some key points of consideration.
I also feel it is quite difficult to comment on lymphoedema without talking about WHAT actually
increases the rate of lymphoedema, breast cancer as a whole doesnt. It is the particular surgical
techniques, chemotherapy agents, patient factors, that increase the risk. A patient who has a
simple lumpectomy and SLNB has a significant different rate of lymphoedema compared to
mastectomy + ALND + ART.
There has been no comment on L-Dex or any objective measuring tool to determining
lymphoedema, which is necessary in this day and age.
Title: Promoting Early Detection of Necrotizing Soft Tissue Infection of the Upper Extremity
in Patients with History of Breast Cancer: A Case Report
Version: 2 Date: 07 Apr 2025
Reviewer:  Demetris Savva
Reviewer's report:
very interesting topic, well analysed. minor modifications needed before accepting!
in the discussion section, a more detailed analysis of the surgeries of debridement should be
identified. how many times debridement surgery took place, at what extend/level was the final
debridement before Polynovo placement etc.
latest lab work before decease should be also outlined.
Title: Promoting Early Detection of Necrotizing Soft Tissue Infection of the Upper Extremity
in Patients with History of Breast Cancer: A Case Report
Version: 2 Date: 11 Apr 2025
Reviewer's report:
Dear Editor,
I thank you for the opportunity to review this case report considering lymphedema-assosiated
severe upper limb infection.
In general, the case report is interesting and considers an important but rare topic. I have a few
remarks considering the manuscript:
1) line 116 – please add (ICU) as used later as abbreviation
2) lines 117/134/136  - I suppose generic names for antibiotics/products should be used
3) line 118 – please clarify, which cultures were taken (pus, blood) and were all positive, was
bacterial susceptibility testing to antibiotics performed.
4) lines 171-176 – the reference (9) appears to be erroneous, as it does not study the subject
that is referred to. Additionally, the claim the authors make is most likely not right. My
recommendation would be to remove lines 171-176 entirely, which would also improve the
integrity of the manuscript.
5) lines 183 -188  - the authors state, that this may be the first such case illustrated in literature,
and therefore giving such a broad recommendation based on disease affecting millions annually
seems highly exaggerated. In general, treatment recommendations for an entire patient group
cannot be made based on a single case, except in truly exceptional circumstances.
- my recommendation is to remove lines 184-188 entirely. More appropriate and justified
conclusion would be something as follows:
”This is one of the first known cases to discuss NSTI in the context of upper limb lymphedema
in a breast cancer survivor. The possibility of such a serious condition must be acknowledged
when treating an upper limb infection in a patient with a history of breast cancer.”
Title: Promoting Early Detection of Necrotizing Soft Tissue Infection of the Upper Extremity
in Patients with History of Breast Cancer: A Case Report
Version: 4 Date: 06 Jun 2025
Reviewer:  Demetris Savva
Reviewer's report:
An interesting case report analysed.
In discussion section, classification of lymphedema should be mentioned with possible planning/
followup protocols. It is important to mention the need for post surgical followup in cases of
possible lymphedema aka. breast cancer patients, as well any protocols involving lymphedema
patients, physiotherapy, possible manual therapy or surgical intervention needed in the last
stages.
Title: Promoting Early Detection of Necrotizing Soft Tissue Infection of the Upper Extremity
in Patients with History of Breast Cancer: A Case Report
Version: 4 Date: 17 Jun 2025
Reviewer's report:
"PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
N/A - there are no statistics in this study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: This is revised manuscript addressing the question of cellulitis and
necrotizing infection in breast cancer survivors. The authors have described the case well and
have appropriately addressed all the queries raised by the reviewers. This is not a detailed review
of literature and I find it difficult to believe that this is the first such case.
REQUESTED REVISIONS:
In this revised manuscript the one revision that I would suggest is to omit the phrases that this is
first such report and that there is no such previous report; simply state that this is are case which
highlights the need for both physicians and patients to be vigilant about such serious infections.
ADDITIONAL REQUESTS/SUGGESTIONS:
none"
Title: Promoting Early Detection of Necrotizing Soft Tissue Infection of the Upper Extremity
in Patients with History of Breast Cancer: A Case Report
Version: 5 Date: 30 Jun 2025
Reviewer:  Demetris Savva
Reviewer's report:
Corrections were done according to the reviewers comments.
Staging of lymphedema however has still being omitted.
Four-stage system designated by the International Society of Lymphology should be outlined
in the discussion section, for a more overall discussion of the topic and easier reading through
for a reader.
The other points are edited according to the comments!
Title: Early Menopause as an Independent Risk Factor for Postoperative Atrial Fibrillation in
Women Undergoing Coronary Artery Bypass Grafting: A Retrospective Cohort Study
Version: 2 Date: 08 May 2025
Reviewer:  Tongku Liu
Reviewer's report:
The title of the manuscript: “The Correlation Between Early Menopause in Women and
the Incidence of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: A
Retrospective Cohort Study”. Based on the entire text, it is recommended to revise the following
issues.
1. Modify the title from "The Correlation Between Early Menopause in Women and the
Incidence of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: A
Retrospective Cohort Study" to: "Early Menopause as an Independent Risk Factor for
Postoperative Atrial Fibrillation in Women Undergoing Coronary Artery Bypass Grafting: A
Retrospective Cohort Study"
This change better reflects the study design and core findings.
2. In the Methods section of the Abstract, specify the exact variables adjusted for in the IPTW
analysis.
3. In the Introduction, it is recommended to highlight: "Although early menopause is associated
with increased cardiovascular risk, its impact on POAF after CABG remains unclear. This study
is the first to investigate..."
4. In the Methodology section, add specific details about POAF monitoring methods (e.g., "daily
12-lead ECG + continuous cardiac monitoring").
5. Clearly define the criteria for menopausal age (e.g., whether it requires 12 months of
amenorrhea).
6. In the Statistical Methods section, supplement with: Multicollinearity testing (VIF values)#
Model fit indicators (Hosmer-Lemeshow test)
7. In the Discussion section, cite recent literature (e.g., 2023 Nature Reviews Cardiology review)
to support the relationship between estrogen and ion channels.
8. Add clinical implications: "For women with early menopause, preoperative assessment of
IL-6 or CRP levels could be considered, along with evaluation of potential benefits from anti-
inflammatory therapies (e.g., colchicine)."
9. Consistently use "early menopause" throughout the manuscript; avoid mixing with "premature
menopause."
10 Spell out "postoperative atrial fibrillation (POAF)" at first mention, then use the abbreviation
thereafter.
11. Some references are outdated (e.g., [6][7]); prioritize citations from the last 5 years (e.g.,
2022 ESC guidelines for POAF definition).
12. References need to be written in a uniform format. For example, the authors of references
should always be kept in six places, and if there are more than six authors, the sixth place should
be denoted by et al.; Some references do not include the year of publication; Some references
do not contain DOI.
These modifications will enhance the clarity, rigor, and clinical relevance of the manuscript
while maintaining consistency with current research standards.