JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Understanding the effect of gender-based violence on uptake and utilisation of HIV
prevention, treatment, and care services among transgender women: a qualitative study in the
Greater Kampala Metropolitan Area, Uganda
Version: 0 Date: 17 Sep 2022
Reviewer's report:
The paper is very well written. Below are some considerations to improve the paper.
Background
Sentence that begins “Globally, it is estimated that more than 19% of transgender women…”
– needs a reference
Results
It is unclear how many of the main themes could be attributed to the study participants. For
example, was a theme mentioned by the majority of participants or only 1-2 participants?
Consider reframing results write-up to reflect how Table 2 is set up i.e., individual, community,
and health care setting. This may aid better flow and reading of the results section.
Quotes vary considerably from one quote to support a theme/subtheme to several. Suggest
balancing out the themes.
Recommend not repeating similar quotes from participants:
Pg. 12 – Repeated twice ““Some doctors think they are very religious, so they at times preach
to us instead of offering the services we need. Because we also have bibles on our phones, they
don’t need to emphasize that God loves us. Since you know what may happen after reaching the
healthcare facility, we would rather refrain and stay home.” (FGD participant, Kampala)”
Consider reducing the number of quotes for “Shunning healthcare facilities” specifically
describing “gossiping”
These quotes are similar, consider only including one:
“I won’t say that it has never happened, having sex with someone and the condom is off. I didn’t
realize the man had removed the condom and when I asked him about it, he held my head,
pushed it back and told me to shut up. Then from that moment, should I call it rape?! It must
have been rape because it didn’t feel consensual anymore. I was fighting to free myself and he
didn’t want to use a condom.” (IDI participant)
“Some of them [sex clients] do not want to use condoms. I have personally experienced this
when having sex with a client. At first, he may be putting on a condom and as time goes on,
he removes it. So, you are like why did you remove the condom? And the best thing he (client)
will do is push your head back. He commands you to just shut up and continue. What I do is
to also kick him off.” (IDI participant)
Conclusions
Suggest including more specific information on the type of tailored training needed by healthcare
providers in this setting to reduce and alleviate discrimination against transgender women.
Title: Understanding the effect of gender-based violence on uptake and utilisation of HIV
prevention, treatment, and care services among transgender women: a qualitative study in the
Greater Kampala Metropolitan Area, Uganda
Version: 4 Date: 23 Mar 2023
Reviewer's report:
I appreciate the opportunity to review this revised manuscript. The authors have done a great
job responding thoroughly to each comment. I have a two minor concerns about the revised
manuscript:
1.  On page 5, Line 194 reads, "This involved identification of unique themes for both the base
and run first run,  which were afterward used to calculate the saturation ratio." if "base and run
first run" is a typo, please correct. If not, please define "base and run first run."
2. On page 24, Line 889, the manuscript indicates that consent was obtained from "subjects and
their legal guardians."  It's not clear why  participants aged 18 years and older would require
consent from legal guardians nor why they are labelled "subjects" instead of "participants."
Title: Understanding the perspective of women who use the Billings Ovulation Method®: a
focus group study.
Version: 1 Date: 29 Mar 2023
Reviewer's report:
Although the findings of the study do not seem new, it is a good topic to remind caregivers of
Natural Family Planning methods because some people are suitable for using it. Please explain
the authors about the rigor( Trustworthiness )of the data.
Title: Understanding the perspective of women who use the Billings Ovulation Method®: a
focus group study.
Version: 1 Date: 09 Apr 2023
Reviewer's report:
The present study investigated user experiences with FABMs. Overall, the manuscript is well
written but the Methods section needs some improvement.
A section on how methodological rigor were ensured has to be added to the manuscript
Generally, the authors need to refer to COREQ checklist for reporting qualitative studies to
strengthen the method section.
Who conducted the interviews and how was issue of gender influence addressed if the
interviewer was an opposite sex in relation to the participants?
Can the authors explain why they used convenience sampling technique instead of purposive?
Title: Effect of Educational Intervention Based on Theory of Planned Behaviour on Promoting
Preventive Behaviours of Oral Cancer in Rural Women
Version: 1 Date: 26 Dec 2022
Reviewer's report:
Specific Comments
1. Please check Line no 7 of introduction as it is contrary to line 6 which you mentioned.
2. In Sampling it should be power of test .
3. In methodology you have to properly explain how the two rural centres were selected and
how many women were selected from each centre.
4. Is it a longitudinal study as it is no where mentioned which study approach you have used.
General Comments
1. English needs to be revised.
2. The reference style should in accordance with the journal style.
3. The research question of the study is not clear.
4. The authors should clearly specify the sampling procedure they have adopted for the study,
and justify why they have used this sampling. If possible cite some literatures where the authors
have used this type of sampling procedure for conducting case control studies.
5. The authors needs to specify the policy recommendations following their study.
Title: Effect of Educational Intervention Based on Theory of Planned Behaviour on Promoting
Preventive Behaviours of Oral Cancer in Rural Women
Version: 1 Date: 03 Jan 2023
Reviewer's report:
Thank you for the opportunity to review the manuscript entitled ‘Effect of Educational
Intervention Based on Theory of Planned Behaviour on Promoting Preventive Behaviours of
Oral Cancer in Rural Women” The manuscript has addressed the important issue of educational
intervention for behaviours change for organ cancer. The manuscript is well written with
a clearly mentioned methodology. However, I have several comments and suggestions for
improvements to the manuscript.
- The selection of respondent's criteria is not clear
- Sampling design somewhere it is mentioned as random sampling, and somewhere, it is
mentioned as convenient sampling. The discrepancies in the sample section and allocation need
to be addressed to make it clear to readers.
- The sample size determination explained is not clear. The authors have merely provided the
references but failed to mention how they derived the samples clearly. You may also use the
sample size determination formula to derive the sample size.
- Need more clarity and elaboration on how the intervention was given, authors may consider
giving a few sub-headings under the educational intervention
- Provide the Ethical approval number or code
- Give the title to the tables at appropriate places
- Need proofreading of a manuscript to avoid grammar errors and clear presentation of ideas.
- Report the limitations of the study
Title: Effects of spinal anaesthesia and intravenous general anaesthesia on the absorption of
normal salinein patients undergoing hysteroscopic endometrial resection: An observational
study
Version: 2 Date: 05 Apr 2023
Reviewer's report:
1. Based on the research flowchart, it appears that this study is a randomized controlled clinical
trial. However, the clinical trial registration indicates that it is an observational study. The
anesthesia method is selected randomly, which suggests that this study leans more towards
intervention-based clinical research. Personally, I believe that this study's methodology aligns
more with intervention-based research.
2. Why did the author choose general anesthesia and tracheal intubation to complete such surgery
in terms of anesthesia method selection? Typically, for hysteroscopic endometrial resection with
a surgical time of less than 30 minutes, intravenous anesthesia or laryngeal mask anesthesia is
utilized. General anesthesia with tracheal intubation is usually considered as the last option.
3. The most fundamental observation indicator is liquid absorption, which can be easily
measured in clinical practice. However, considering the multiple factors that may affect its
accuracy, does the author have quality control standards in place for measuring this indicator.
4. The author compared the intergroup differences of various indicators between S1, S2, PF1,
and PF2 groups. However, it is unclear why the S group and PF group were not merged and
compared. In the result” The absorption of normal saline was significantly positively correlated
with the operation time (r = 0.895, P < 0.001) (Table 2).” Does it refer to merging all data or
just referring to a few groups?
5. Table 4 indicates that the hematocrit (HCT) level has not fallen below 35% mostly.
Anesthesiologists who frequently administer anesthesia for hysteroscopic surgery are aware that
prolonged surgery time increases the risk of water intoxication, which can cause the HCT level
to drop to 30-35%. It is possible that the study participants included individuals who did not
experience water intoxication or did not absorb a significant amount of liquid. Moreover, the
data in Table 2 shows that the liquid volumes were mostly between 300-400ml. As such, the
results' applicability is limited.
6. Based on research primarily focused on fluid volume absorption, other fluid load monitoring
indicators, such as lung ultrasound and non-invasive cardiac output monitoring, may offer
additional information.
Title: Effects of spinal anaesthesia and intravenous general anaesthesia on the absorption of
normal salinein patients undergoing hysteroscopic endometrial resection: An observational
study
Version: 2 Date: 05 Apr 2023
Reviewer:  Thitikan Kunapaisal
Reviewer's report:
The authors have a good job in the work.
I 've the questions
1. How do you calculate the weight of the liquid absorbed by surgical drep to  the volume in ml?
2.Why do you use 30 minutes to be cut of point time? I didn't see  about that in the introduction.
3. I think  it will be easier to see the changes  graph of SBP,DBP, HR, an SpO2 at different
time points among 4 groups.
Title: Effects of spinal anaesthesia and intravenous general anaesthesia on the absorption of
normal salinein patients undergoing hysteroscopic endometrial resection: An observational
study
Version: 2 Date: 07 Apr 2023
Reviewer:  Camilla Di Dio
Reviewer's report:
In my opinion, the analyzed topic is interesting enough to attract the readers’ attention. The
aim of this clinical trial was to observe the effects of spinal anesthesia and intravenous general
anesthesia on the absorption of normal saline in patients undergoing hysteroscopic endometrial
resection.
I think that the abstract of this article is very clear and well structured.
In my opinion, the discussion could be studied in depth and extended. Maybe, it could be useful
the evaluation of a possible index which could predict these kind of complications. I suggest as
an example these two protocols : PMID: 31657456, PMID: 35793638. Because of these reasons,
the article should be revised and completed. Considered all these points, I think it could be of
interest for the readers and, in my opinion, it deserves the priority to be published after minor
revisions.
Title: Effects of spinal anaesthesia and intravenous general anaesthesia on the absorption of
normal salinein patients undergoing hysteroscopic endometrial resection: An observational
study
Version: 4 Date: 29 Apr 2023
Reviewer:  Camilla Di Dio
Reviewer's report:
I wanted to thank the authors for making the requested changes and thus broadening and
clarifying the discussion.  Thanks to these modifications the article is much more flowing and
clearer and that's why it is deserves the priority to be published
Title: The effectiveness of educational program based on health belief model on promotion of
puberty health concepts among teen girls: A cross-sectional study in north of Iran
Version: 2 Date: 25 Feb 2023
Reviewer's report:
Dear Author
- Mention to period of data collection in Method.
- How was the method of sampling students in each school?
- In table 3, on what basis is the age of puberty calculated? Did you mean the age of first
menstruation or menarche?
- In table number 4, mention the range of scores of each structure. To make the table clearer, it
is suggested; Add the average score change of pre and posttest; and its statistical test, instead of
statistical results before and after intervention.
- It is suggested to use statistical tests to check the effect of education based on the model on
puberty behavior.
- Report univariate and multivariate analyses for the relationship between puberty health in
participants and HBM constructs with controlling for confounding variables (Information and
fear about menstruation before menarche, …).
- In discussion, mention to different of present study with similar studies clearly.
- According to similar studies in this field, the innovation of the present study must be discussed,
it seems it is so weak.
- Mention the weak and strong points of your study.
- In conclusion, write down your practical suggestions.
- What do you suggest for future studies?
Regards
Title: Factors associated with self-report of polycystic ovary syndrome in the Coronary Artery
Risk Factor Development in Young Adults Study
Version: 2 Date: 29 Mar 2023
Reviewer's report:
"PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses a testable research
question(s) (brief or other article types: is there a clear objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
No - there are minor issues
EXECUTION - Are the experiments and analyses performed with technical rigor to allow
confidence in the results?
No - there are minor issues
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work technically
sound? If not, can revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Self-Reporting of PCOS , unrecognised PCOS and factors associated
with increased self-report of PCOS. Given the complexity of the topic studied, the subject has
been fairly well dealt with.
REQUESTED REVISIONS:
1. Self Report PCOS: Did a doctor or nurse ever tell you had PCOS?
Were any tests conducted for a doctor or nurse to ‘tell’ a subject had PCOS? Does ‘tell’ refer to
a suggestion or was it confirmed based on other features? What features/Characteristics would
these be? Were the subjects asked to do further tests to confirm the diagnosis?
2. There is a lot of ambiguity in this study, given the nature of the subject PCOS and its criterias
with heterogeneity in phenotypic presentation, even self-reporting although clearly defined is
based on a doctor or nurse telling, however what is the ‘telling’ based on is not defined.
3. Unrecognised PCOS is grouped on ‘No or Not Sure’, since the telling part is not clearly
defined this group also becomes unclear.
4. Women who self –reported PCOS were not tested or evaluated, neither are criterias/ presence
of which symptoms etc are used to by doctors or nurses to ‘tell’ patients, neither the authenticity
of Self- Reporting in confirmed or further evaluated to validate the presence of PCOS.
5. However, the study has a clear and well defined purpose/hypothesis and has performed tests
and results to test the hypothesis.
6. The area of study is relevant and study of reasons of undiagnosed or unrecognized PCOS is
important to help in future diagnosis and criteria's of diagnosis.
7. Please add a graphical representation of results if possible especially in keeping with the aim
and purpose of the study."
Title: Factors associated with self-report of polycystic ovary syndrome in the Coronary Artery
Risk Factor Development in Young Adults Study
Version: 2 Date: 11 Apr 2023
Reviewer's report:
-Editing and thorough proofing should be conducted throughout the paper, particularly the
abstract and discussion has typos and misspelled words.
-The authors discuss potential variation in PCOS by race and discuss this within the context
of Black women, but the reference they cite indicate no differences by race/ethnicity,. From a
health disparities standpoint, there needs to be greater justification for examining interactions
by race, and how this will benefit specific groups. In the present form, it is not well-justified as
to why the authors used race as an interaction term initially. Further, the authors need to make
a stronger case in the intro for including food insecurity in the model. Social determinants of
health is fairly broad and it is unclear why these specific determinants were selected. The same
goes for diabetes and obesity.
- There needs to be more discussion on the obesity findings. Why do the authors think women
with unrecognized PCOS were more likely to have obesity?
-Authors should correct the significance level to account for multiple comparisons and reduce
the likelihood of Type I error.
- A major limitation is the cell sizes in these comparisons. This should be acknowledged in
limitations, along with the implications for comparison of unbalanced cell sizes.
-The conclusions do not seem reflective of the findings. In addition, the authors mention a need
for more work in black women, but why? There is no mention of black women in the discussion,
so this seems to come out of nowhere.
Title: Factors associated with self-report of polycystic ovary syndrome in the Coronary Artery
Risk Factor Development in Young Adults Study
Version: 4 Date: 13 Apr 2023
Reviewer's report:
Thank you for addressing the recommended revisions. The authors did a nice job thoroughly
revising the manuscript based on the reviewers' comments. I believe this manuscript was greatly
improved and will make a meaningful impact to the field.
Title: Factors associated with self-report of polycystic ovary syndrome in the Coronary Artery
Risk Factor Development in Young Adults Study
Version: 4 Date: 25 Apr 2023
Reviewer's report:
"PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: The revised manuscript is well rounded now, having responded to
the queries raised.
ADDITIONAL REQUESTS/SUGGESTIONS:
The revised manuscript is more acceptable."
Title: Ovarian endometrioma increases the embryo aneuploid rate: an analysis of 7092 biopsied
blastocysts from fertile monogenetic disease carriers
Version: 2 Date: 11 Jan 2023
Reviewer's report:
I have reviewed the manuscript, entitled “Ovarian endometrioma increases the embryo
aneuploid rate: an analysis of 7092 biopsied blastocysts from fertile monogenetic disease
carriers" for BMC Women's Health.  In this article, the authors compared aneuploidy rates
between fertile patients with and without endometrioma undergoing IVF cycles for PGT-M.
The key finding was that endometriosis significantly increases aneuploidy rates. Although the
number of cases in the study group was very low than the control, evaluation in the fertile
population make the study interesting to read and valuable. In my opinion the study can be
accepted after some essential revisions.
My recommendations,
01. What is the rate of bilateral endometiromas in the study group?
02. Please mention post hoc power analysis of the study.
03. The authors stated that the euploid rate was calculated per person. So, how can you compare
the euploid rate between the two groups?
04. Quality of the embryos should be given in the table.
05. What about the mosaicism rate in the two groups? Please mention in the text.
06. What refers to B and P in the table 4. Please mention under the table 4.
07. Numbers belong to the result not to the discussion. So, associated sentences should be
reorganized in the discussion.
08. Please don’t mention lower or higher of any variable that did not reach statistical significance.
Best regards,
Title: Ovarian endometrioma increases the embryo aneuploid rate: an analysis of 7092 biopsied
blastocysts from fertile monogenetic disease carriers
Version: 2 Date: 31 Jan 2023
Reviewer:  Pierfrancesco Greco
Reviewer's report:
I find this article well written and interesting for new IVF techniques for women with ovarian
endometriosis. Regarding the part that discusses women's age as a major factor in blastocyst
aneuploidies I recommend citing the following articles:
Hum Reprod 2021 Dec 27;37(1):80-92. doi: 10.1093/humrep/deab226.
The impact of maternal age on gene expression during the GV to MII transition in euploid human
oocytes
P Ntostis, D Iles, G Kokkali, T Vaxevanoglou, et al.
Case Reports Hum Reprod 2022 Sep 30;37(10):2392-2401. doi: 10.1093/humrep/deac191.
The number and rate of euploid blastocysts in women undergoing IVF/ICSI cycles are strongly
dependent on ovarian reserve and female age
Antonio La Marca, Martina Capuzzo, Maria Longo, et al.
Title: Ovarian endometrioma increases the embryo aneuploid rate: an analysis of 7092 biopsied
blastocysts from fertile monogenetic disease carriers
Version: 3 Date: 05 Mar 2023
Reviewer's report:
I have re-reviewed the manuscript, entitled “Ovarian endometrioma increases the embryo
aneuploid rate: an analysis of 7092 biopsied blastocysts from fertile monogenetic disease
carriers" for BMC Women's Health.  Although the manuscript was improved, all inputs were
not covered in revised version. So some essential revisions should be done before publication.
My recommendations,
01. Post hoc power analysis was not described well. A support of professional statistician can
be taken.
02. As I previously recommended, please don’t mention lower or higher of any variable that did
not reach statistical significance (as in line 202-204).
Best regards,
Title: Ovarian endometrioma increases the embryo aneuploid rate: an analysis of 7092 biopsied
blastocysts from fertile monogenetic disease carriers
Version: 4 Date: 23 Apr 2023
Reviewer's report:
I have re-reviewed the manuscript, entitled “Ovarian endometrioma increases the embryo
aneuploid rate: an analysis of 7092 biopsied blastocysts from fertile monogenetic disease
carriers" for BMC Women's Health. In my opinion, the manuscript is now acceptable for
publication.