Reviewer ’s report  
 
Title: Lesion distribution characteristics of deep infiltrating endometriosis with ovarian  
endometrioma: An observational clinical study  
 
Version: 0 Date: 24 Jan 2020  
 
Reviewer: Justyna Sikora  
 
Reviewer's report:  
 
The aim of study of Kwok et al. was to investigate the characteristic of deep infiltrating 
endometriosis lesion distribution when associ ated with ovarian endometrioma.  
 
The study is very interesting, all the more, it brings a new direction to the diagnosti cs of 
endometriosis. However, I have a few questions:  
 
1.Have you considered use the ENZIAN classification of DIE? Can it together with yours results 
be useful to create map of DIE?  
 
2.In what phase of the menstrual cycle the surgery was performed?  
 
3.Except  for these changes, were another lesion in peritoneal cavity? Superficial endometriosis? 
adhesion?  
 
4.Almost 90% of studied women had previously surgery for OEM, did they have any additional 
pharmacological treatment?  
   Could you check, did the previous op eration concern the same places?  
 
5.It could be more useful when you present results on figures.  
 
6.In Discussion part, it is not clear, where is your observations or conclusions and observations 
from other Authors.  
 
 
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported  by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please spec ify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Accep table  
 
Declaration of competing interests  
Please compl ete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publication of th is 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applyi ng for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is y es to any, please give details below.  
 
I declare that I have no competing interests  
 
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