Reviewer’s report
Title: 
Outcomes of HPV type-specific serostatus do not associate with oral or
genital HPV-carriage in non-vaccinated women followed for three years
Version: 
1 
Date: 
06 Feb 2022
Reviewer's report:
Much of the manuscript is easier to read in this revision and the to make reading
easier:
P7 Re word the following sentence to distinguish better from first analysis,
suggest: 'Secondly, we analysed serological association with the five individual
HPV genotype genital infections'
P9 line 30. Presumably HPV 16 DNA positive is what is intended
P9 line 36 Suggest changing order of words in sentence to 'In our study, these
genital HPV16 carriage cases were still HPV 16 seronegative at the end of the
follow-up period, so with a longer follow-up, some of these women might have
been seroconverted'.
P10 line 58 - words in parentheses should be omitted 
- I think all readers
understand what is meant by 'negative serostatus' 
However the Discussion is both laboured and repetitive. While this may be an
attempt to answer previous reviewer's comments it would be helpful if it is
looked at again, to give the two or three paragraphs only which are required to
sum up the data presented. 
There is a tendency to overuse the word 'the' which can make a sentence more
difficult to read in English. Examples, not exhaustive, can be found on
Manuscript P3 Line 44 
and 51- delete 'the' before 'extremely high' and 'type-
specific' respectively 
P4, line 32- also before 'naturally acquired'
P4 line 48 - also before 'HPV genotpye' and in line 51 before 'seroconversion'
P10 line 44 - similarly, should be 'protective effect against future infection was
higher for high-titer HPV18 antibodies than….'
P11 line 5 omit 'the' before 'knowledge of pregnancy' 
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