JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the
PI3K/AKT signaling pathway
Version: 1 Date: 19 Sep 2022
Reviewer's report:
This is an interesting paper and the content is very good but I suggest the paper can be improved
in the following ways
Abstract
Please modify the headlines based on the format of the journal
- In the method section, please include the year of the study, sampling method, location of study.
-in the result section please emphasizing on the main results.
-In the conclusion part, it is necessary to specify the researcher's proposal to improve the
conditions and use of the beneficiaries
Introduction
Please bring the following items
1- Definition of the research problem
2- The magnitude and importance of the study variable
3- Bringing the variable epidemiology information of the study at the world level, the country
of India and the place of study
4- Bringing theoretical knowledge about the importance of studying
5- Expressing the necessity of conducting the study
Finally, the practical purpose of the study should be stated
Discussion
# Discussion is well written, but it needs the interpretation of authors. Please add your
interpretation and explanations to this section.
Conclusion
# What are your suggestion for future studies?
To strengthen the article, especially in the introduction and discussion section the following
studies are suggested, please to use and cited and add to article reference
- Observance of patients’ rights in emergency department of educational hospitals in south-east
Iran
- Attitudes of Iranian Nurses Toward Spirituality and Spiritual Care
-The effect of educational workshop on emergency department nurses' self-efficacy in patient
training
Best regard
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 2 Date: 08 Apr 2022
Reviewer:  Oskari Heikinheimo
Reviewer's report:
The ms by Want & Jiang includes potentially interesting data. However, the format of the paper
needs significant revision before it can be considered further.
The main points are:
- the current format of the ms is not compatible with a regular research article. I.e.
- the Results section is very lengthy, and contains elements of discussion & references. Please
concentrate on presenting the study results.
- the current Discussion is really not a discussion of the study results. Accordingly, it also
contains only 2 references. The authors are encouraged to rewrite both the Results and
Discussion.
- before possible resubmission, the English language of the ms must be reviewed by a native
English speaker.
- please check the Journal instructions concerning the number of figures and tables allowed. The
current version has numerous figures (albeit as different panels of a figure). In order to improve
clarity of the paper, please cnsider presenting some of those as supplementary materia.
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 3 Date: 09 Jul 2022
Reviewer's report:
1. In Table 1, it is better to present the percentage distribution in terms of column percentages.
This way,  state of affairs of induced abortions among women will be more comprehensible and
understandable to the intended audience.
2. In Table 2, for binomial regression model, it is usual practice to present the results of models
either in Odds Ratio or Predicted Probabilities instead of coefficients. Otherwise, readers will
find it very difficult to comprehend the results of the models.
3. The sentence formation and English of the ms  must be improved.
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 6 Date: 14 Aug 2022
Reviewer:  Monica Malta
Reviewer's report:
The authors addressed several of my critiques, but a few issues remain to be corrected.
1. Grammar and spell check is still needed (e.g. "resarech",  "Organisation", "comfirms", missing
verbs etc)
2. Methods: "Next, we conducted a binomial logistic regression analysis on whether experienced
induced abortion or not." That sentence doesn't make any sense, please explain what you did.
You conducted a binomial logistics regression to evaluate what? To examine the correlation
3. Conclusions: The authors need to read very careful their conclusions, to avoid prejudicial and
judgmental affirmatives that (1) are not scientifically sound and (2) are detrimental to women's
health. One example:
"Unmarried women face confusion and pressure when they become pregnant; while induced
abortions cause great harm to their lives and physical and mental health." This sentence is not
based on the presented data, is highly judgmental and contradicts guidelines from the World
Health Organization, UN Women, CDC, among many others international organizations. For
instance, according to WHO, being able to obtain safe abortion is a crucial part of health care.
Safe induced abortions are NOT detrimental to women’s reproductive health, fertility, overall
physical and mental health. UNSAFE abortion is the key public health problem.
4. Conclusions, same concern explained before: "The second is repeat induced abortion, which
remains a considerable challenge to women’s sexual and reproductive health in China." Why
is abortion a challenge to women’s sexual and reproductive health? This sentence is NOT
scientifically sound, contradicts major organizations working to improve women's health and is
unacceptable for a publication on a journal dedicated to publish articles addressing "all aspects
of the health and wellbeing of adolescent girls and women", as stated on BMC Women's Health
aims and scope...
5. Conclusions, same concern:  "The government should [...] reduce the impact of induced
abortion on women’s health." Once again, what is the impact of safe, legal induced abortion on
women's health? Extensive medical, epidemiological, psychological and sociological evidence
proves that abortion is safe for women and major complications are extremely rare.
In sum, BMC Women's Health is an international journal that publishes sound research about
women's and girls health. Although the study utilized sound statistical methods, the conclusions
are not adequate yet and need another round of review. Please review your discussion/conclusion
section very carefully, avoiding sentences that are scientifically unsound and not supported by
the scientific community.
Safe induced abortion is a crucial part of women's healthcare package. It is a safe medical
procedure, and the right to obtain safe abortion should be protected.
Thanks for the opportunity to review again your manuscript.
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 7 Date: 23 Sep 2022
Reviewer:  Monica Malta
Reviewer's report:
Thanks for the opportunity to review your manuscript. The revised version is better and I have
just a few (minor) suggestions to improve it. Congratulations on this highly important study, I
look forward to seeing it published.
Discussion: "sex ratio of 113.17 for first births" please review, I'm assuming it is 113.17 boys
per 100 girls - but this information need to be included.
Discussion: "By contrast, the sex ratio for second births dropped from 130.29 in the 2010 census
to 106.78 in the 2020 census as the birth control policy was relaxed." same comment, please
clearly describe the rate of boys vs. girls
Discussion: "The interaction terms in the regression results show that the profile of women
who resort to abortion has shifted from well-educated urban women toward rural, less-educated
women, contradicting Zheng et al.,9 who found a shift among women resorting to abortion from
less-educated rural women to well-educated urban women. " Could you add any hypothesis here,
trying to explain this contradiction? The study conducted by Zheng et al. was different? If it
was, what key differences might explain their results?
Discussion: "In addition, the group more likely to undergo induced abortions has shifted from
Han to minority women, a result seldom mentioned in previous studies." Please cite here those
studies
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 8 Date: 13 Oct 2022
Reviewer:  Avijit Roy
Reviewer's report:
Thank you for selecting me as a part of the manuscript. The manuscript entitled “Recent induced
abortion in China” is a very emerging issue in public health from a global background. My
suggestions are below:
Your abstract doesn’t meet the standard. I have highlighted some suggestions. You have to
thoroughly revise the abstract section.
Abstract: Add the research objective in the background section. What is the final sample size
in your research it needs to add in the methods section. The results are also comprehensive and
add some data in the results part or you may add the odds value where it is applicable. Rewrite
the conclusion section based on factors and policy perspectives.
In regression analysis section line 239 replace it with predictor variables or independent
variables, it would be more specific.  What are the survey questions? You have to mention all
categories which you have used i.e. age (15-19 years, 20-24 years and so on). “Unlike in Western
countries, marital status is an important factor in induced abortion, as premarital childbearing is
unacceptable in China.41,42” remove the sentence, is it necessary in this part? You have already
mentioned this in your background section. I have never seen wealth quintile factor which is
most important if possible includes the variable.
In the discussion section (line 464), you mentioned the prevalence of abortion is higher in
premarital cohabitation than post-marital. However, in the background of China, it is not
accepted widely and it mostly happened by private clinics or non-professionals. So why it
is happening and what are the role of medical professionals and also govt. Another thing is
that from the best of my knowledge it may be that post-marital abortion most often occurred
whenever maternal complications raised or unintended pregnancies by the couple. Therefore,
you should address this matter and what are the real scenarios in the Chinese background.
Considering the rural vs urban background it needs to more describe in your discussion part.
I would suggest the author follow the article to get more details "Examining the rural-urban
divide in predisposing, enabling, and need factors of unsafe abortion in India using Andersen’s
behavioral model." BMC Public Health, 2022, https://doi.org/10.1186/s12889-022-13912-4
Other issues are:
The manuscript has several typo errors which make me very difficult to read the manuscript.
So many sentences are not clear.
The title should have a time frame it would be more helpful to readers. Therefore title must be
revised.
I hope these suggestions would help the author to revise the manuscript.
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 8 Date: 22 Oct 2022
Reviewer's report:
The researchers have focused on an important issue.
The manuscript fulfills all the scientific standards necessary to be published.
Results and Discussion are sufficient and well-organized.
The abstract includes necessary and sufficient data.
Further statistical analyses are not required. In fact, the analyses made by the researchers are
sufficient.
The language of the manuscript is good enough to understand and there are not any spelling or
punctuation mistakes.
The manuscript has sufficient quality and originality to be published in BMC Women's Health.
But I have a recommendation about the title.  Because it does not give information about the
study.
"Frequency of induced abortion and associated factors in China: a cohort study from 2006 to
2016". I wrote this as an example. I think you will find it a better title.
Best wishes
Title: Recent trend and correlates of induced abortion in China: Evidence from the 2017 China
Fertility Survey
Version: 8 Date: 25 Oct 2022
Reviewer's report:
Overall, an excellent study. I would like to suggest to make following changes
1) I personally think that the topic of the study should be changed. Instead of "Recent Induced
Abortion in China", "Correlates of induced abortions in China: Evidence from Chinese Fertility
Survey 2017".
2) I think there are some problems with the way results have been discussed. For example
"Panel 6A shows that, for the earlier birth cohorts (35–44, 45–54, and 55–60), the predicted
hazards of induced abortion are higher for women in urban areas than for those in rural areas.
However,in later birth cohorts(15–24,25–34), rural women aremore likely to undergo induced
abortions, which is consistent with the above results. Panel 6Bindicates that in earlier birth
cohorts(35–44,45–54,55–60), Han women aremore likely to experience induced abortions,
while in later birth cohorts (15–24,25–34), ethnic-minoritywomen aremore likely to experience
induced abortions".  I do not agree with these statements as the results are being discussed with
reference to the other category. For example Panel 6A shows that predicted hazards are lower in
later birth cohorts. Please check these results again. Also, in log regression, if certain variables
were controlled for, how were they controlled. Were they added in the model in the first step?
if yes, ORs should be replaced with AORs (Adjusted Odds Ratio).
Title: Changes in women’s physical function in mid-life by reproductive age and hormones: a
longitudinal study
Version: 1 Date: 09 Aug 2022
Reviewer's report:
This study aims to evaluate associations of both chronological and reproductive age with
physical function in midlife women. Strengths of the study include the longitudinal design, use
of objective physical function measures, and the large general population sample.
The manuscript addresses an important question with sound methods and analysis.  The
manuscript is well-written, and the results are clearly presented.  The Introduction provides
a thorough review of the current literature and context for the current study.  The Methods
are generally clearly described, and the statistical analyses used are appropriate to address the
questions of interest.  The main results are  clearly and accurately presented, and the conclusions
are appropriate.
There are just a few points for clarification.
1.  Figure 1 (flow chart): Several of the numbers in the boxes do not agree  with what was
subtracted through exclusions.  Please correct or clarify if this is due to participants falling into
multiple exclusion categories.
2. It would be helpful to state how many women contributed 1 visit, 2 visits, or 3 visits to the
analyses.
3. Please provide a bit more detail about the re-invitations.  For example, what was the timing
for the re-invitations relative to the  usual visit schedule?
4. Did you consider running the analyses without the pre-FMP women (with FMP time set to
0)?  It would be interesting to see whether or not the results were similar without them.
Title: HIV is still a major public health problem among pregnant women attending ANC in
Referral Hospitals of the Amhara Regional State, Ethiopia: a cross sectional study
Version: 1 Date: 25 Sep 2022
Reviewer's report:
REVIEW COMMENTS
1. Abstract section
-Need to be consistent in the first objective i.e prevalence vs proportion
-Wide confidence interval in factors to estimate the parameter eg. Positive syphilis status
-Results, conclusion and recommendation needs to be critically supporting each other i.e
conclude your finding and objective and recommend based on your finding
2. Plain language summary
-Shares the above comment, “….. Special attention should be given to enhance public awareness
regarding HIV….”, the study did’t  address such variable while it has been recommended with
attention, BCC, Pillars of PMTCT …are the promising strategy with FMOH
3. Introduction
-Rewrite the sentence in line 118 which states as there is no such study in …..
4. Methods
4.1. Study design and setting
-The study setting/area lacks representatives of the topic stated, the geographical spacial
distribution of selected hospital indicates lack of representatives, it is true for number of hospitals
selected in the region
- Better to write in the setting of the study: PMTCT sites, ART sites, initiatives in the region
4.2. Source and study population
# It is clear but the selected hospital and samples lacks to address the source population to be
generalized
# “Pregnant women who declined to be screened for HIV were excluded from the study” line
151-152 is not convincing because through counseling of its own protocol there is a means to
address
4.3. Sample size  determination
-Why sentinel site with such small proportion to has regional study
-The sampling procedure is not clearly stated
5. Discussion
=The issue of sample size have been evidenced by your discussion, you stated as there are studies
in the region with better proportion than the sentinel surveillance proportion, if so, what is the
reason to use small proportion?
=Narration from line 359-362 states as there is increased need of pregnancy among HIV infected
mothers as there is increased confidence of mothers to have HIV free generation. Cite the
reference.
=Better to add more in the Implication of the finding
Title: HIV is still a major public health problem among pregnant women attending ANC in
Referral Hospitals of the Amhara Regional State, Ethiopia: a cross sectional study
Version: 1 Date: 11 Oct 2022
Reviewer's report:
Review report:
1. Abstract
Line 29: Methods, you have to explain in a single sentence the methods used to collect your data
and not only how data were analysed.
Line: 40, is there any background for this classification of income (family monthly income
greater than 8001 ETB (1 USD = 56 ETB)
Line: 45, conclusion, better to state whether your findings are self-sufficient to draw the
conclusion or further studies are needed?
2. Background
Note well written
3. Methods
Line 87-90: What is the relevance of this paragraph or sentences to your objective, I think it will
be good to replace with  other issues (The epidemiology of HIV in Ethiopia is heterogeneous
with large variations across geographic areas, sex and  population groups. In urban  area, the
prevalence is seven times higher than the  one in rural areas. It is also more prevalent among
women. (1.2%) than men (0.6%) (7).)
Line: 144; three hospitals out of what?
Line: 156: Pregnant women who declined to be screened for HIV were excluded from the study.
It is their right it could not be used as the exclusion criteria, please explain it
4. Result
well written
5. Discussion
this section needs some modification
General Evaluation
it contains more of others literature instead of justifying what is the problem. Also it better to use
international organization data such from WHO and others in this part rather than local studies
that you heavily discussed them. Please improve this part and need to read the literature.
Title: HIV is still a major public health problem among pregnant women attending ANC in
Referral Hospitals of the Amhara Regional State, Ethiopia: a cross sectional study
Version: 3 Date: 27 Oct 2022
Reviewer's report:
Review/report of author’s amendment
Thank you for inviting to re-evaluate the author’s amendment of my comment as a reviewer, I
review the point by point amendment of the comment and it has been founded corrected as per my
comment and they reason out on those issues with the issue of clarity. So, with acknowledging
the authors commitment and effort, I recommend the manuscript to be published with a potential
benefit of evidence for scientific community, policy makers and programmers.
Title: Melatonin suppresses serum starvation-induced autophagy of ovarian granulosa cells in
premature ovarian insufficiency
Version: 0 Date: 27 Jul 2022
Reviewer's report:
In this manuscript, the authors were reported an "Melatonin suppresses serum starvation-induced
autophagy of ovarian granulosa cells in premature ovarian insufficiency". Very interestine and
quite valuable data is presented in this manuscript, however several minor issues remained to
be cleared before its publication.
- Despite the nice flow in the text, several grammatical and syntax errors are still present. Please
consider revising the entire manuscript again.
- The clinical relevance of the research could be more elaborated specially in the discussion
section.
- In what basis the melatonin concentaration was selected?
- Please state how the primer sequences were obtained. Were they designed or copied from
different publications.
- In the discussion, the authors are suggested to discuss the relevant findings regarding additional
effect of melatonin on paracrine activity of granulosa cells in dose dependent manner which is
potentially could be associated with autophagic response?
10.1016/j.procbio.2021.03.008 ;  10.34172/bi.2021.23499   ;   10.3389/fcell.2021.686551
- Also, how authors are certain that Human ovarian granulosa-like tumor cells (KGN) represent
POI characteristics?
Title: Melatonin suppresses serum starvation-induced autophagy of ovarian granulosa cells in
premature ovarian insufficiency
Version: 0 Date: 11 Aug 2022
Reviewer's report:
The overall story line of this manuscript is complete. But I personally feel that there are the
following shortcomings:
1. The entire manuscript is based on cell lines and lacks data on primary cells, human samples,
and mouse models. It is recommended to add relevant data.
2. Then the expression of related miR-15a-5p/Stat3 and PI3K-Akt-mTOR pathway related genes
was detected, which can indicate that they are related, and it is impossible to directly conclude
who inhibits who
Title: Association study of Bif-1 gene expression with histopathological characteristics and
hormone receptors in breast cancer
Version: 2 Date: 31 Mar 2022
Reviewer's report:
The manuscript is interesting and concerns BIF-1 gene expression in breast cancer molecular
subtypes. Despite the great potential of the topic selection, in my opinion, the article requires
significant corrections:
- Firstly, the names of genes used in the manuscript should be standardized and written in
accordance with the applicable rules
- The manuscript requires linguistic and stylistic correction, preferably by a native speaker
- There is no information on the assessment of gene expression in non-cancerous tissues
(negative control)
- In my opinion, the conclusions are inadequately formulated taking into account the aim of the
study; the authors focus more on the description of the research method than on the expression
of the selected gene
- Please include the justification why in a significant percentage of the studied patients it was
not possible, for example, to determine the receptor expression status
- It would be valuable if the study group were characterized in more detail
- The information on the limitations of the study is incomplete, please provide deeper analysis