Reviewer’s report
Title: 
The role of serum 
β
-trophin and endostatin in patients with polycystic
ovary syndrome: are they correlated?
Version: 
0 
Date: 
23 Aug 2020
Reviewer: 
Sarantis Livadas
Reviewer's report:
Title: The role of serum 
β
-trophin and endostatin in patients with polycystic
ovary syndrome: are
3 they reliable? Reliable for what, please clarify
Abstract: One sentence explaining the possible role of Endostatin and Trophin in
the pathophysiology of PCOS.
Results: Since BMI and WHR was different among groups, all results should be
adjusted for BMI and WHR, since IR is strongly related to these factors.
Table 5 is misleading. How do you compare the existence of IR, when HOMA-
IR values between groups were 3.93±1.25 vs. 3.67±0.99, p:ns
Discussion, first paragraph: The incidence of PCOS ranges 6-8% in those
diagnosed with NIH criteria, whereas it escalates to 10-15% when Rotterdam
criteria are used. In the present study, Rotterdam were used, accordingly this
sentence should be corrected.
Discussion last paragraph: Please replace EG with ES.
A molecular ratio of ES vs. 
β
-trophin, could be of interest, showing perhaps if
this parallel rise is comparable with controls or higher in either PCOS group.
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