JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Anxiety, Depression, and Stress: A Comparative Study between Couples with Male and
Female Infertility
Version: 1 Date: 26 Feb 2024
Reviewer's report:
Dear authors,
I read with interest your manuscript entitled "Anxiety, Depression, and Stress: A comparative
study between Couples with Male and Female Infertility".
Overall, I think the topic of the article is intriguing. The study is well-designed and the results
are presented in a clear way.
I have some suggestions to the authors:
- Please, review the English in which this manuscript has been written, in order to make some
passages smoother and more understandable, particularly in the introduction and discussion.
- It would be interesting to make some parallelism with trans-gender population (refer to PMID:
37374095)
- Today, the incidence of POR is increasingly higher, which can be a problem causing anxiety in
patients. The authors could discuss this by citing, for example, this manuscript: PMID: 38242686
- Inositols can be useful in women suffering from ovulatory disorders to improve ovulatory
function, so the authors could cite articles such as the following: PMID: 37798243
Title: Maternal Satisfaction with Delivery Service and Associated Factors among Women Who
Gave Birth at Public Hospitals in Guji Zone, Southern Ethiopia
Version: 2 Date: 08 Jan 2024
Reviewer:  Awol Yemane
Reviewer's report:
The research topic is good, and I want to thank the authors for their efforts.
The English language of the manuscript needs significant improvement. There are multiple
grammatical errors, typos, punctuation problems, and formatting issues. The conclusion of the
abstract section should be improved by being more specific about the type of association, such
as short duration of labor instead of just duration of labour, short waiting time instead of waiting
time, and good fetal outcome instead of just fetal outcome. Additionally, recommendations
should rely on the results rather than preexisting knowledge of the authors. The background
section is too lengthy and should be shortened.
In the methods section, please focus on the obstetrics services provided by the hospital rather
than including historical statements. Provide information on the number of annual deliveries at
the selected hospital, cesarean section rate, type of obstetric services offered, and number of
specialists and midwives. Can you support your satisfaction cut point of 73 with a reference
citation?
My biggest concern is with the sampling method. If it was systematic random sampling, how
did you end up with 41% of mothers who had a Cesarean section? The Cesarean section rate
in public hospitals in Ethiopia is barely higher than 15%, so it seems selective inclusion may
have occurred.
Was logistic regression done in a stepwise fashion? Please elaborate on this in the results section.
Have you included any factors in the multivariate analysis that may not have been statistically
significant at the univariate level but are clinically significant?
Please calculate the confidence interval for satisfaction.
In the discussion section, please focus on important findings and include references to support
your arguments. Ensure that citation formats adhere to the standards of the journal. The argument
for mode of delivery needs to be more convincing; please provide further justification.
In your recommendations, stick to your results and consider studying focused ANC and
assessing supervision of compassionate and respectful care practices as future research topics
or remove them.
Title: Maternal Satisfaction with Delivery Service and Associated Factors among Women Who
Gave Birth at Public Hospitals in Guji Zone, Southern Ethiopia
Version: 5 Date: 25 Feb 2024
Reviewer:  Awol Yemane
Reviewer's report:
Thank you,  most of the issues have been addressed satisfactorily. However, there are some
minor issues that need to be considered.
Study setting
It is better to focus on the health cadres rather than the historical perspectives of the hospital.
Thus elaborate on the number of health professionals, such as the number of midwives, general
practitioners, IESOs, if available number of OBGYNS.
Can you provide a clear reason why you purposively selected the two hospitals, while other
hospitals provide comprehensive maternal and neonatal care?
Operational definitions
What is the importance of subcategorizing the APGAR score into three, clinically it is a good
APGAR score (>= 7) or a low APGAR score (<7). If low APGAR score, it is an indication for
resuscitation, if if good the prognosis is good.
Results
Table 1
List the chronology based on the magnitude, especially religion and residence. The higher the
figure, the first it will be listed.
Title: Maternal Satisfaction with Delivery Service and Associated Factors among Women Who
Gave Birth at Public Hospitals in Guji Zone, Southern Ethiopia
Version: 5 Date: 29 Feb 2024
Reviewer's report:
I appreciate the effort the authors have put into revising the manuscript. Overall, it is a
commendable study with valuable information. I have a few minor suggestions for improvement.
The abstract is clear, but restructuring the last few sentences in the conclusion section could
enhance its strength.
The methods and results sections are well-described.
Regarding the setting, could you please verify the number of births at the study health facilities?
It seems both facilities had the same number (4612). I am curious whether this is a typo or a
genuine coincidence. Additionally, consider rephrasing line 73 and line 129 for better clarity.
In lines 422-428, where the authors propose reasons why women may prefer a cesarean
birth, I recommend a more nuanced discussion. Consider exploring the possibility that, due to
emergencies and obstetric complications, women needing a cesarean section experience shorter
waiting times and labor.
Please also check the reference by Strong AE, 2021, which discusses stress and panic
during the uncertainty of the second stage in low-resource settings, potentially leading to
incidents of mistreatment (Reference: Med Anthropol. 2021 May-Jun;40(4):307-321. doi:
10.1080/01459740.2021.1884075. Epub 2021 Mar 110). The literature suggests that women
generally prefer vaginal birth (see reference 28), with fear of mistreatment and uncertainty about
the outcome being more likely reasons than fear of pain.
Could you please verify the data on the vacuum rate? At 24.6% (same as the CS rate), it appears
rather high and unusual.
Overall, the paper has significantly improved. I recommend reviewing the table titles once more
and consider revising lines 468-471. Additionally, you may want to use the term "childbirth" or
"birth" instead of "delivery" and consider using 'women' instead of 'mothers.'
Title: Maternal Satisfaction with Delivery Service and Associated Factors among Women Who
Gave Birth at Public Hospitals in Guji Zone, Southern Ethiopia
Version: 7 Date: 24 Mar 2024
Reviewer:  Awol Yemane
Reviewer's report:
Although the manuscript has shown significant improvement, it still requires extensive revision
and proofreading by a native English speaker. Additionally, academic terminology should be
used more frequently in the discussion section.
Operational definition can you rephrase the following statement
Normal fetal outcomes were defined as a fetus who was delivered alive or well or lacked at
least one of these conditions (i.e. low birth weight, birth trauma, perinatal asphyxia, meconium
aspiration syndrome, APGAR score <7, early neonatal death, or stillbirth)[40, 41].   Remove the
term "at least" as it would give a different meaning.
Title: Pelvic floor muscle contraction automatic evaluation algorithm for pelvic floor muscle
training biofeedback using self-performed ultrasound
Version: 3 Date: 01 Jan 2024
Reviewer's report:
The aim of this study was to develop an algorithm for the automatic determination of pelvic
floor muscle (PFM) contraction using self-performed bladder US videos to verify whether it is
possible to automatically determine PFM contraction from US videos.
I have the following comments to the Authors:
• The abstract is incomplete and should include a summary of the results of the entire study.
• Please revise your English and check for typos and tense mistakes.
• Methods: The study design is not clear, please state it explicitly.
• Methods: Considering that the snowball sampling is subject to numerous selection biases,
please declare it.
• Methods: What was the setting in which the study was conducted? Please, specify it.
• Methods: The Authors should include a paragraph in the section of material and methods about
the ethical statement obtained to conduct the study.
• Methods: Should the Authors consider in the selection criteria gynecological pathologies such
as endometriosis considering that it can play an important role in pelvic floor muscle disfunction
(PMID: 27718502, PMID: 31049643)?
• Methods: Authors should clearly state the outcomes of the study, and which were the related
endpoints.
• Discussion: Authors should include a comparison of their study with similar studies already
present in the literature.
Title: Pelvic floor muscle contraction automatic evaluation algorithm for pelvic floor muscle
training biofeedback using self-performed ultrasound
Version: 3 Date: 02 Jan 2024
Reviewer:  Kijin Kim
Reviewer's report:
This study is an attempt to develop an automatic algorithm for PFM contraction using transverse
bladder images, and is expected to be used as useful evidence to suggest the importance of PFM
contraction and ways to utilize it.
A description of the limitations of the research results due to the limitations of the data used in
this study is required.
It is believed that it is difficult to analyze Bladder's movements.
It is believed that the overall results obtained are significantly insufficient to achieve the purpose
of the study.
Overall, there is a need to collect more data and apply improved technologies.
It is believed that it is difficult to develop detailed discussions due to limited data.
It would be advisable to submit again after the above-mentioned parts have been supplemented.
Title: Pelvic floor muscle contraction automatic evaluation algorithm for pelvic floor muscle
training biofeedback using self-performed ultrasound
Version: 7 Date: 14 Feb 2024
Reviewer's report:
The article has been reviewed by the authors, and all points mentioned during the review have
been corrected. Additionally, the article has been deemed suitable for publication. This suggests
that the authors have successfully addressed any issues highlighted during the review, and the
article now meets the requirements for publication.
Title: Pelvic floor muscle contraction automatic evaluation algorithm for pelvic floor muscle
training biofeedback using self-performed ultrasound
Version: 7 Date: 28 Feb 2024
Reviewer:  Kijin Kim
Reviewer's report:
Overall, there has been modified, but there is still a need to collect more data and apply improved
techniques. Therefore, there is a need for additional research in this area or the need to add
defense concept sentences.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 0 Date: 17 Sep 2023
Reviewer's report:
The article Clinical characteristics and risk factors of Cervical intraepithelial neoplasia
complicated with Vaginal intraepithelial neoplasia is interesting and current.
Human Papillomavirus infections are a very extensive field of study, and the lesions they cause
are still poorly known. The author of the paper very well presented the connection between
multiple HPV infection in CIN and WAIN lesions in older patients (57 years old) compared
to CIN (41 years old), and warns us about the importance of respecting these facts during the
monitoring of precancerous lesions.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 0 Date: 29 Jan 2024
Reviewer's report:
I read the Manuscript titled “Clinical characteristics and risk factors of cervical intraepithelial
neoplasia complicated with vaginal intraepithelial neoplasia” which falls within the aim of the
Journal.
Although the manuscript can be considered already of good quality, I would suggest following
recommendations:
- I suggest a round of language revision, in order to correct few typos and improve readability.
- Authors should consider recent evidence about HPV-related lower genital tract lesion,
considering the potential role of ant-HPV vaccination and results of this study. I would be glad
if the authors discuss this important point, referring to PMID: 37978580
- I suggest authors to add a reference to relationship between surgical treatment for cervical
disease and obstetrical outcomes, considering the importance of adequate and precise treatment
even in precancerous lesions. I would be glad if the authors discuss this important point, referring
to PMID:  33140628.
Because of these reasons, the article should be revised and completed. Considering all these
points, I think it could be of interest to the readers and, in my opinion, it deserves the priority
to be published after minor revisions.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 0 Date: 01 Feb 2024
Reviewer's report:
Authors present present a small retrospective study comparing the result of patients with CIN
with and without VaIN. Although it is interesting to evaluate these differences I am concerned
that the results and methodology used in this paper do not add new information to what is already
known.
- I suggest that authors review the english language because some paragraphs of the paper is
confusing to read
-The introduction could benefit from given a more concise background of the current problem
rather than stating the different classifications of VaIN, when it is clear that almost all lesions
are caused by HPV infections.
- There is no clear objective of the study
- Methodology is poor. There is no specification of how patients were diagnosed and if those
included in the group without VaIN had a vaginoscopy to confirm there were no lesions.
Statements of inclusion and exclusion criteria are non-specific.
The abstract mentions logistic regression was performed but there is no mesntion of this in the
statistical analysis.
- Results and discussion are poor. Not focusing on a clear objective.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 0 Date: 01 Feb 2024
Reviewer's report:
I read with great interest the manuscript, which falls within the aim of this Journal and offers
a high-quality overview of the topic.
The methodology is accurate and conclusions are supported by the data analysis. The tables and
figures are clear and interesting.
Although the manuscript can be considered already of high quality, I would suggest taking into
account the following minor recommendations:
- I suggest another round of language revision, in order to correct a few typos and improve
readability.
- Inclusion/exclusion criteria should be better clarified by extending their description.
- I find it interesting to include a reference to risk factors that influence the recurrence of high-
grade cervical lesions (see PMID: 37747763).
-What is already known on this subject?
-What do the results of this study add?
-What are the implications of these findings for clinical practice and/or further research? It is
important to report the results obtained by the authors in the context of clinical practice and to
adequately highlight what contribution this study adds to the literature already existing on the
topic and to future study perspectives.
- Discussions can be expanded by citing relevant articles about long-term risk factors for the
recurrence of HVP-related lesions (see PMID: 37401466).
- The authors have not adequately highlighted the strengths and limitations of their study. I
suggest better specifying these points.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 1 Date: 20 Feb 2024
Reviewer:  Sveinung Wergeland Sørbye
Reviewer's report:
All comments have been addressed. The response to the comments is adequate and improved
the manuscript.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 2 Date: 28 Feb 2024
Reviewer:  Sveinung Wergeland Sørbye
Reviewer's report:
After careful consideration of the revised manuscript and the authors' responses to the feedback
provided in previous review rounds, I am pleased to note that all concerns have been thoroughly
addressed. The revisions have significantly improved the manuscript, making it a valuable
contribution to the field of Women's Health. The authors have demonstrated a commendable
effort in clarifying and enhancing their work based on the feedback received. In light of these
improvements and the manuscript's adherence to the high standards of BMC Women's Health, I
believe it is now suitable for publication. I have no further suggestions at this time and commend
the authors for their diligent revisions.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 2 Date: 08 Mar 2024
Reviewer's report:
Dear authors,
My comments are almost the same. I leave it to the editor decision, if he will accept the article.
Another comments
Lines 68-73
The low incidence of VAIN could be attributed to its often asymptomatic nature and reliance
on singular diagnostic methods like the ThinPrep cytologic test (TCT) or colposcopic biopsies.
The diagnosis relies on pathological examination and its preliminary screening relies on either
thinprep cytologic test (TCT) or colposcopic application of 5% acetic acid multipoint biopsy5.
Comment: I do not understand. Diagnosis of what? VAIN diagnosis? You repeat the same thing
and the second sentence makes no sense. The diagnosis of VAIN does not rely on a cytology
test. A colposcopic examination should be performed with the application of 5% acetic acid and
then a colposcopically guided biopsy may be performed.
Lines 196-200
For skin infections, HPV types can be categorized into low-risk (e.g., 1, 2, 3, 4, 7, 10, 12, 15) and
high-risk types (e.g., 5, 8, 14, 17, 20, 36, 38). Similarly, for mucosal infections, low-risk types
include 6, 11, 32, 34, 40, 42, 43, 44, 53, 54, and high-risk types include 16, 18, 30, 31, 33, 35, 39.
Comment:  Missing citation.
The International Agency for Research on Cancer (IARC) of WHO distinguishes 3 groups of
HPV. HR genotypes include HPV classified into group 1 (HPV 16, 18, 31, 33, 35, 39, 45, 51, 52,
56, 58, 59) and group 2A (HPV 68). According to the IARC, 13 HPV genotypes are currently
classified into the HR HPV group, HPV genotypes 16, 18, 31, 33 and 45 are considered the most
important for the development of human malignancies.
Source: PMID: 19350698
Lines 224-228
The latest evidence shows that surgical treatment of the CIN was associated with an increased
risk of preterm delivery, lower birth weight and preterm premature rupture of membrane before
37 pregnancy weeks compared to untreated women, especially in a CKC and LLETZ procedure.
Comment:  The abbreviations CKC and LLETZ should be explained. It is better to cite the
Cochrane database – see PMCID: PMC6457639.
Table 3
Last line: Replace HIS by HSIL.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 3 Date: 13 Mar 2024
Reviewer's report:
Dear authors,
I have no more other comments. I leave it to the editor decision, if he will accept the article for
publication in BMC Women's Health journal.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 3 Date: 15 Mar 2024
Reviewer's report:
The quality of the manuscript has improved thanks to the changes made. I think it could be of
interest to the readers and, in my opinion, it deserves the priority to be published.
Title: Clinical Characteristics, HPV Involvement, and Demographic Risk Factors in Women
with Cervical Intraepithelial Neoplasia Complicated by Vaginal Intraepithelial Neoplasia
Version: 3 Date: 16 Mar 2024
Reviewer:  Sveinung Wergeland Sørbye
Reviewer's report:
All comments have been addressed. The response to the comments is adequate and improved
the manuscript.
Title: Investigating genetic links between blood metabolites and preeclampsia
Version: 1 Date: 20 Nov 2023
Reviewer:  Hussein Wahhab Saleh Rabeea
Reviewer's report:
I extend to you my sincere greetings and appreciation
allow me to express my support for what they stated in the article, the title and its consistency
with the content were good, and the language of the research and the style of its presentation
were good, but there were some spelling wrongs:
61- interventions remaining  replace to ...  remain
78- risk prediction,  clinical diagnosis replace to ..  risk prediction and clinical diagnosis
115- mention a reference ...
the researcher did not take the ages of the adult from whom the samples were taken, and the
integrity of the scientific method used in the research is very good, and the integrity of the
scientific method used in the research is very good
After minor modifications, they can publish the research
Title: Investigating genetic links between blood metabolites and preeclampsia
Version: 1 Date: 25 Nov 2023
Reviewer's report:
Thank you for inviting me to review this manuscript from Lin et al. Authors presented an analysis
of using a MR for understanding the casual relationships between metabolites and preeclampsia.
For the manuscript, following concerns might need to be addressed:
1. For the metabolite pathways that authors mentioned in the introduction, they might consider
to introduce that more with specific pathways they might interested in. List of the categories and
potential metabolite might not sufficient. And the direction of changes for metabolites might be
another thing to consider (for example, a rise of certain metabolite might be a potential risk or
protect to the PE).
2. For the GWAS summary statistics, many reported GWAS with larger sample sizes for PE (for
different ancestries) are available. Data from FinnGen is great but did authors consider use a
GWAS results from a more large EUR cohort or use the combined results from multiple studies?
3. What are the confounding variables that authors considered in the IV selections? The authors
might need to provide a full list of those confounders. Although authors mentioned several in
the result section, it might need to state them in the methods.
4. Instead of giving the metabolites IDs, authors might provide the actual names for those
metabolites that they mentioned in the results.
Minor concerns:
1. Authors might need to improve their writing and consider to break down the very long
sentences in the manuscript.
Title: Investigating genetic links between blood metabolites and preeclampsia
Version: 3 Date: 25 Dec 2023
Reviewer:  Hussein Wahhab Saleh Rabeea
Reviewer's report:
Dear editor, I would like to thank you for your trust in allowing me to revise this article.
The material and methods were good, and the researcher completed the necessary modifications
to this  paper
Results and discussion were laid down in a proper scientific way and I enjoyed reading them