Reviewer’s report
Title: 
Investigation of the relationship between hot flashes, sweating and sleep
quality in perimenopausal and postmenopausal women: the mediating effect of
anxiety and depression
Version: 
0 
Date: 
31 May 2020
Reviewer's report:
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Investigation of the relationship between hot flashes, sweating and sleep quality
in perimenopausal and postmenopausal women: the mediating effect of anxiety
and depression
Aim: the purpose of this study is to verify whether anxiety and depression play a
mediating role between hot flashes, sweating and sleep quality.
The topic is very interesting, and I believe in this association in clinic practice. I
have never read about it. I appreciated it. 
My considerations are on methods:
Methods: authors evaluate hotflashes through 
Kupperman index. Do they have
number of hotflashes /day /night? It would be interesting in this study.
It would be good if authors analyse 2 groups: one with low sleep and the other
with good sleep quality and the possible different associations with anxiety and
depression in these groups. 
Are the methods appropriate and well described?
If not, please specify what is
required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which
controls are required in your comments to the authors.
No
Are the conclusions drawn adequately supported by the data shown?
If not,
please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you
recommend an additional statistical review?
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is recommended, please specify what aspects require further assessment in your
comments to the editors.
I am able to assess the statistics
Quality of written English
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manuscript:
Acceptable
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