JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Development of Prognostic Models for HER2-positive Metastatic Breast Cancer in
Females: A Retrospective Population-Based Study
Version: 0 Date: 30 Jul 2024
Reviewer's report:
The study aims to develop and validate nomograms for predicting BCSS and OS in patients with
HER2+ MBC. Using data from the SEER database, the authors employed various statistical
methods to identify prognostic factors and create web-based tools for clinical use.
Major Revisions
The study lacks external validation using independent datasets. If possible, identify and use
another large dataset to validate your models.
The SEER database does not provide detailed information on HER2-targeted therapies and
specific chemotherapy regimens, which could impact the accuracy of the prognostic models.
If feasible, incorporate more granular treatment data from other sources or discuss the
implications of these missing details in greater depth.
The study is retrospective in nature, introducing inherent biases.
Provide a more detailed discussion on the need for prospective studies to validate the
nomograms.
Minor comments:
Verify that all cited references are the most current and relevant.
I suggest to quote and discuss the following related papers:
Di Maio M, et al. Evolving treatments and outcomes in HER2-Positive metastatic breast
cancer: Data from the GIM14/BIOMETA study. Breast. 2023 Dec;72:103583. doi: 10.1016/
j.breast.2023.103583. Epub 2023 Sep 25. PMID: 37783133; PMCID: PMC10551556.
Miles D, et al. Ann Oncol. 2021 Oct;32(10):1245-1255. doi: 10.1016/j.annonc.2021.06.024.
Epub 2021 Jul 2. PMID: 34224826.
Blondeaux E, et al. Clinical outcomes of patients with breast cancer relapsing after
(neo)adjuvant trastuzumab and receiving trastuzumab rechallenge or lapatinib-based therapy:
a multicentre retrospective cohort study. ESMO Open. 2020 Aug;5(4):e000719. doi: 10.1136/
esmoopen-2020-000719. PMID: 32817059; PMCID: PMC7437709.
Title: Development of Prognostic Models for HER2-positive Metastatic Breast Cancer in
Females: A Retrospective Population-Based Study
Version: 1 Date: 04 Dec 2024
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Authors have adequately addressed the query raised. Authors have
included details on limitation and elaborated the dicussion section.
ADDITIONAL REQUESTS/SUGGESTIONS:
Authors have performed the changes in the manuscript that have improved the readability of
the research.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 1 Date: 13 Oct 2024
Reviewer's report:
Thank you very much for the opportunity to review the manuscript.
The manuscript presents a rare case of an intrauterine device (IUD) migration leading to
its unusual final position in the infraumbilical skin. The case report describes the clinical
presentation, diagnosis, and subsequent management of this complication. The authors provide
an in-depth review of intrauterine device use, complications, and the mechanisms behind
intrauterine device migration. The patient described had no serious complications, and the device
was successfully removed without the need for anesthesia. Overall, the manuscript has been
written well and in the scope of the journal.  There are several points that should be addressed
before acceptance.
1. I would suggest including more recent studies on IUD migration and the risk factors associated
with migration in order to support the discussion part.
2. Try to provide a more detailed explanation of the mechanical processes that lead to migration
in postpartum patients in order to improve the strengths of the manuscript.
3. I would suggest providing a broader discussion of alternative management approaches.
4. If you could provide a follow-up plan by showing a more comprehensive management
approach, this would give more strength to your manuscript.
I would be happy to review the revised manuscript again.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 1 Date: 16 Oct 2024
Reviewer's report:
Thank you for giving me the opportunity to review this interesting case report "Migrated Intra
Uterine Device to Infra umbilical skin".
However, I have some comments and recommendations:
Comments:
Title: - Is appropriate for the content of the article.
Abstract:- Represents a suitable summary of the work.
Case:- The methods and results have been well explained.
Conclusions:- Are justified on the basis of the study.
Recommendations:
References:- Stick to the format of the journal.
General:- Revise language, grammar and syntax.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 1 Date: 17 Oct 2024
Reviewer:  Samaneh Rokhgireh
Reviewer's report:
Dear Authors
Thanks for your interesting reports. There are some points to be considered.
1-In the  abstract part that you mentioned, the mechanism of IUD effect is induction of
endometrial atrophy, it is better to state the type of hormonal IUD for this effect.
2-It is better to add patient's,  BMI in case presentation section.
3-You didn't mention if  your patient have any pain symptoms after inserting IUD?
4-Did your patient have breastfeeding at the time of IUD
5-It is better to summarize the conclusion part.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 1 Date: 17 Oct 2024
Reviewer:  Marzieh Beigom Bigdeli Shamloo
Reviewer's report:
Due to the valuable efforts of the authors, it is suggested that this article be sent to case report
journals and that articles with more power study be published in this journal.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 1 Date: 18 Oct 2024
Reviewer:  Pavan Kumar Dammalapati
Reviewer's report:
I appreciate the authors for submitting their valuable clinical work.
The migration of the IUD's to  different parts of the body has been documented in the literature.
Novelty is lacking in this manuscript.
I wish the authors all the very best.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 4 Date: 23 Nov 2024
Reviewer's report:
Thank you for giving me the opportunity to review this interesting case report "Migrated Intra
Uterine Device to Infra umbilical skin".
Comments:
Title: - Is appropriate for the content of the article.
Abstract:- Represents a suitable summary of the work.
Case:- The methods and results have been well explained.
Conclusions:- Are justified on the basis of the study.
Recommendations: Accept
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 4 Date: 24 Nov 2024
Reviewer:  Phuc Nhon Nguyen
Reviewer's report:
Thank you for your work. However, the case  is not novel. This condition has been reported in
the literature. Please refer to these papers.
Arif SH, Mohammed AA. Migrated intrauterine device presented as anterior abdominal wall
abscess. J Surg Case Rep. 2019 Jun 14;2019(6):rjz174. doi: 10.1093/jscr/rjz174. PMID:
31214315; PMCID: PMC6565824.
Wani I, Syed A, Maqbool M, Bakshi I, Bhat H, Andrabi FU, Mohsin N. Intrauterine
contraceptive device migration presenting as abdominal wall swelling: a case report. Case Rep
Surg. 2011;2011:305914. doi: 10.1155/2011/305914. Epub 2011 Oct 19. PMID: 22606574;
PMCID: PMC3350241.
Gebremichael A, Teka H, Abadi KK, Siferih M, Moges M, Arusi M, Shiferaw A. Missed
Diagnosis of Perforation and Intraperitoneal Migration of an Intrauterine Device and Its
Management in a Resource-Limited Setting: A Case Report. Int Med Case Rep J. 2024;17:71-76
https://doi.org/10.2147/IMCRJ.S441386
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 4 Date: 26 Nov 2024
Reviewer:  Yuquan Chen
Reviewer's report:
This article presents a unique case of an intrauterine device (IUD) migrating to the infra-
umbilical skin, a location not previously documented. While the report is intriguing and detailed,
it requires significant revisions to enhance clarity, structure, and depth. The introduction,
while informative, lacks focus and diverts attention to general benefits of IUDs rather than
narrowing in on the rare complication of migration. The discussion of the migration mechanism
remains speculative and is insufficiently supported by evidence, requiring a stronger connection
between identified risk factors such as postpartum insertion and breastfeeding with the migration
trajectory. Additionally, the manuscript does not delve deeply into the diagnostic tools utilized,
offering a superficial description of ultrasound findings without adequately explaining how
these corroborated the clinical suspicion or comparing this diagnostic approach with standard
practices.
The case’s emphasis on the noninvasive removal of the IUD is disproportionate and overshadows
other critical aspects of the report. While the removal is noteworthy, greater attention should be
paid to the patient’s presentation, differential diagnosis, and alternative management options.
Moreover, the reporting style varies significantly across sections, with some areas being overly
detailed while others lack depth. This inconsistency diminishes the report's overall coherence
and impact. Comparisons with similar cases are minimal, limiting the reader’s understanding of
how this case stands out or aligns with existing literature on IUD migration. While references
to other cases are included, a more thorough comparative analysis would add significant value.
The included visual aids, such as the trajectory diagrams, are underwhelming and fail to enhance
understanding. High-quality, annotated illustrations or medical images would better illustrate
the key findings. Additionally, the conclusion does not adequately address the broader clinical
implications of this case. Offering actionable recommendations for follow-up protocols or
preventive measures would make the report more impactful for clinicians. By addressing these
shortcomings and providing a more focused and evidence-based narrative, this report can better
contribute to the understanding and management of rare IUD complications. Major revision is
strongly recommended.
Title: Migrated Intra-Uterine Device to Infra-umbilical skin: A rare Case Report
Version: 5 Date: 09 Dec 2024
Reviewer:  Antonio Bandala-Jacques
Reviewer's report:
Dear authors: Thank you for submitting your re-reviewed manuscript
You have addressed most issues. I can only see this remaining ones
A) You fixed your introductory sentence to "Intrauterine devices (IUDs) are most effective,
relatively safe and long acting reversible contraceptives (LARCs) "
The word "most" here does not make the sentence grammatically correct. I would remove it
B) Please pluralize:
1)  'Devices' in "Misplaced device may not necessarily always follow uterine perforation at the
time of insertion as it could be with later trans-mural migration "
2) 'Clinicians' in "insertion by less experienced clinician"
3) 'Picture' in "Patients with migrated IUDs have varied clinical picture"
4) 'Devices' in "Misplaced device may be first incidentally detected with radiography being
ordered for other medical illness "
5)  'Cycles' in "she had regular menstrual cycle coming every thirty days "
C) In "Unlike the previous cases reported, this will help explain the potential migration sites of
IUD are not limited to the pelvis" please change 'the' for 'that'
D) Please revise the word "stayed" in "which stayed for 3 to 5 days of moderate amount with
minimal discomfort.", Maybe 'lasted'?. Also, moderate amount of what?
I recommend "She had regular monthly menstrual cycles that lasted 3 to 5 days, with moderate
amount of fluid, and minimal discomfort"
E) Please revise "The abdomen was soft and no area of tenderness." to "The abdomen was soft
with no area of tenderness."
F) I believe unnoticed is spelled without a hyphen (in "Misplacement of IUDs may happen due
to un-noticed ")
Otherwise, I think the contents of the manuscript are adequate, an all the comments have been
addressed
Title: Prevalence of Endometriosis in Women Undergoing Laparoscopic Surgery for Various
Gynecological Indications: A Jordanian Multi-Center Retrospective Study
Version: 0 Date: 03 Sep 2024
Reviewer's report:
thank you for giving me the chance to review this paper
despite good overall merit, I have some minor comments:
please revise english by native speaker
did you perform a sample size analysis?
can you add some limitations of diagnostic laparoscopy with white light (eg doi 10.1111/
aogs.13866)
can you add more details on the sites of endometriosis: superficial, deep one (eg doi  10.1002/
ijgo.14089; DOI: 10.3390/diagnostics13111876)
Title: Prevalence of Endometriosis in Women Undergoing Laparoscopic Surgery for Various
Gynecological Indications: A Jordanian Multi-Center Retrospective Study
Version: 0 Date: 14 Sep 2024
Reviewer:  Michael Odida
Reviewer's report:
This is an important topic. The manuscript is fairly well written. However, there are some issues
which need to be addressed.
It is not clear how many cases had histological confirmation. The number of cases with
histological diagnosis should be indicated.
In the data analysis, the authors have brought in many analyses. The authors intended to analyze
the prevalence of endometriosis in relation to demographic characteristics, parity, number of
miscarriages, ectopic pregnancies, and cesarean sections. Since the number of cases is limited
and there were a number of variables, one cannot perform many tests. I suggest that Chi square
tests be used to assess the association between endometriosis and the other variables if the
numbers of cases allow. The use of odds ratio is not informative.
In the discussion, the authors should endeavor to offer plausible reasons why some variables are
associated with endometriosis.
Title: Prevalence of Endometriosis in Women Undergoing Laparoscopic Surgery for Various
Gynecological Indications: A Jordanian Multi-Center Retrospective Study
Version: 1 Date: 21 Oct 2024
Reviewer:  Michael Odida
Reviewer's report:
The manuscript has been corrected as I had suggested. However, in the tables, there are  issues
to be addressed, especially the small numbers, 0, 1 etc. Some of these could be combined if
statistical tests are to be done. For example, parity of three or more could be a category.
Title: Prevalence of Endometriosis in Women Undergoing Laparoscopic Surgery for Various
Gynecological Indications: A Jordanian Multi-Center Retrospective Study
Version: 1 Date: 02 Nov 2024
Reviewer's report:
Dear
this is a well-written study on an important and not well-documented issue
I suggest reviewing the English language and syntax to improve readiness
I would like to know the experience and background of the surgical team performing the
laparoscopic evaluation? how many first surgeons?
I find it interesting to comment on the limits of diagnostic laparoscopy to detect occult diseases.
However you must provide more recent data on this topic (e.g. doi 10.1111/aogs.13866; doi:
10.3389/fonc.2021.737938)
Title: Prevalence of Endometriosis in Women Undergoing Laparoscopic Surgery for Various
Gynecological Indications: A Jordanian Multi-Center Retrospective Study
Version: 2 Date: 03 Dec 2024
Reviewer:  Michael Odida
Reviewer's report:
I would like to thank the authors for this manuscript which has been revised. It is well written,
although there are some minor issues. In the study design, it is reported as a cohort study. It is
better to use cross sectional.
In the results section, figures less than ten, should be written in words. Under 3.3, 29.7 should
read 29.7%.
Within the text, there are some words starting with capital letters. These should be corrected.
Title: Experience of the menopause transition in Irish women and how it impacts motivators,
facilitators, and barriers to physical activity engagement
Version: 2 Date: 17 Aug 2024
Reviewer's report:
Thank you for the opportunity to review your paper. The menopause transition is a crucial
stage in midlife for women, significantly impacting their overall well-being. Your study, which
explores the experiences of Irish women during the menopause transition and its effects on their
motivations, facilitators, and barriers to physical activity, is both timely and well-written.
However, I have a few suggestions for improvement:
1. Table 1: It would be helpful to include the criteria for each body mass index (BMI) category
for clarity.
2. Study Limitations: While you’ve acknowledged some limitations related to the qualitative
design, such as generalizability and small sample size, it would be beneficial to also address
other potential limitations like subjectivity, researcher bias, and the challenges of replicability.
3. Interpreter’s Experience: Can you provide more information on the experience of those
interpreting the qualitative data? This could help readers assess the robustness of the analysis.
4. Investigator Training: Did the lead investigator conducting the intervention receive sufficient
training in qualitative data collection? Detailing this would strengthen the study’s credibility.
5. Reliability and Validity Concerns: Since the lead investigator was the sole person responsible
for reading, re-reading, and conducting the initial coding of the data, there is a potential risk to the
reliability, validity, and credibility of the findings. Consider discussing how this was addressed.
6. Textual Summary of Tables: While Tables 1 and 2 are informative, a summary of their
contents should also be presented in the text for better integration into the narrative.
7. Discussion and Implications: The discussion of findings and implications could benefit from
being broken into shorter, more focused paragraphs to enhance readability and clarity.
8. Supplementary Materials: I suggest including all interview or survey questions in the
supplementary materials for reference. This would provide readers with a fuller understanding
of the data collection process.
Title: Experience of the menopause transition in Irish women and how it impacts motivators,
facilitators, and barriers to physical activity engagement
Version: 2 Date: 20 Sep 2024
Reviewer:  Phuc Nhon Nguyen
Reviewer's report:
Dear authors,
Thank you for your topic concerning mid-life women's health. The topic is  important.  However,
the number of cases is not greatly sufficient to support the issue. Moreover, the study did not
reveal the  concomitant  diseases that could impact on women's health  at this stage rather than
menopause transition. The authors should improve the data.
Best regards,
Title: Decoding Acculturative Stress and Psychological Distress in Mexican Immigrant
Women: Insights from a Path Mediation Analysis
Version: 2 Date: 02 Jan 2024
Reviewer:  Mark Lusk
Reviewer's report:
This is a very good manuscript that will advance the understanding of challenges facing Mexican
women immigrants.  A  few changes will improve the final paper.
A citation is needed after the 1st sentence in the 3rd paragraph.
More importantly,  in the opening section, the definition of acculturative stress is too limited.
It is not strictly "the  stress associated with adopting the dominant culture's beliefs and values"
because  Latino/Hispanic and other immigrants do not necessarily do better when they adopt
the dominant culture, but  are more resilient and successful when they draw on their culture of
origin to address the challenges of succeeding in a new cultural environment.  It is inaccurate
to assume that acculturation  into and accommodation of dominant culture is a prerequisite of
immigrant success. The retention of original core cultural values is predictive of well-being.
Regarding the early statements that research on Latino immigrants tend to lump nationalities into
one group is not fully accurate. There is a very large literature that focuses solely on Mexican
immigrants and a fair number of studies that focus exclusively on Mexican women immigrants.
An underlying narrative of this study is that  immigrant Mexican women  deal with huge,
nearly insurmountable obstacles to their success in immigrating to the United States. This is a
familiar and often unnecessarily singular perspective in immigration research.  In fact, given the
challenges that Mexican immigrant women face, they are remarkably resilient and successful.
Note the significant literature on the Hispanic Health/Mental Health Paradox. The author(s)
should refer to this line of research emphasizing the strengths and assets approach to immigration
and well-being.
Using risk and resilience theory, Familismo is a protective factor. It is but one of many used by
Latino immigrants; others include: comunidad, compadrazgo, respeto, and  "la fe y la fuerza."
The data for the study are 20 years old. It would be helpful to validate the research with focus
groups with Mexican immigrant women. I recognize that this may be a focus in the next paper
rather than this one.
It may be that the reference section needs minor changes to fit BMC Women's Health guidelines.
Here is an example of the journal's citations:
Van Kamp I, Van Loon J, Droomers M, De Hollander A. Residential environment and health: a
review of methodological and conceptual issues. Rev Environ Health. 2021;19(3–4):381–401.
Title: Decoding Acculturative Stress and Psychological Distress in Mexican Immigrant
Women: Insights from a Path Mediation Analysis
Version: 4 Date: 08 Aug 2024
Reviewer:  Mark Lusk
Reviewer's report:
The author has fully addressed all of the concerns I raised in the initial review. The author has
taken a more nuanced view of psychological distress among migrants and has drawn on the
literature that documents their resilience, strengths and the protective factors that mediate and
ameliorate trauma and distress. As a result, the final manuscript  is ready, in my estimation, for
publication.