Reviewer’s report
Title: 
The Relationship Between Menopausal Syndrome and Gut Microbes
Version: 
0 
Date: 
15 Jul 2022
Reviewer's report:
I read with great interest the manuscript, which falls within the aim of this
Journal. In my honest opinion, the topic is interesting enough to attract the
readers' attention. Nevertheless, authors should clarify some points and improve
the discussion, as suggested below.
Authors should consider the following recommendations:
- Manuscript should be further revised in order to correct some typos and
improve style.
- I would suggest to discuss, at least briefly, the potential effect of visnadine,
prenylflavonoids and bovine colostrum on microbiota and vaginal symptoms
(authors may refer to: PMID: 29452786).
- I recommend to add a summary about the role of microbiome in the
pathogenesis of gynecological conditions (refer to: PMID: 33851803).
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
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from apparent manipulation?
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