JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Posttraumatic stress symptoms and postpartum anxiety among Palestinian women: The
mediating roles of self-esteem and social support
Version: 1 Date: 05 Apr 2023
Reviewer:  Akihiro Seita
Reviewer's report:
Dear Authors,
Thanks so much for this very interesting and important manuscript. I read it with great interest.
I am no expert on this specific area of science (behavior science?), but the logic flows well, and
the analysis looks sensitive.
I have one inquiry.
The first is on your key finding. At the end of your Findings chapter, you mentioned, “…Our
results indicated that the association between stressful life events and postpartum anxiety was
fully mediated by social support and self-esteem” (underlined by myself).
You may clarify what do you mean by “meditated”? Is it something “lightened”? or even
“solved / relieved”? I assume this is “lightened.” If so, can you indicate, if not quantify how
much “lightened”? I assume, again I am no expert on this area, it is not sensible to assume that
postpartum anxiety is completely relieved universally even with very strong social support and
self-esteem.
The above is important to understand the implication of your study. It is very natural to
understand self-esteem and social protection would mediate postpartum anxiety. Your study
clearly confirmed this which is very helpful: still it is rather common sense to see the person
with self-esteem and social protection would manage (mediate?) postpartum anxiety.
If such mediation is measurable, it would be good to state so, so that we can understand
the importance of such self-esteem in the care of pregnant women as you mentioned in your
recommendation, namely “…It may also be worthwhile to develop and implement interventions
during pregnancy which serve to enhance a women’s sense of self-esteem during this particularly
stressful period.”
Title: Effects of body mass index on IVF outcomes in different age groups
Version: 4 Date: 11 May 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses a testable research
question(s) (brief or other article types: is there a clear objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor to allow
confidence in the results?
No - there are minor issues
STATISTICS - Is the use of statistics in the manuscript appropriate?
No - there are issues with the statistics in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
No - there are minor issues
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work technically
sound? If not, can revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: - This is an important study that addressed an important question of
interest to the readers
- Authors did well in dividing population based on their age, given age is an important prognostic
factor.
-Generally the study did meet criteria fore best practice with some comments that will be
discussed later on in revision section
REQUESTED REVISIONS:
- First of all the topic of this study needs revision "Recommendations for good practice in BMI#
Guide IVF clinic according to age" I would suggest something like "impact of body mass index
on xxxxx) rather than using recommendation and guide. also avoid using abbreviation in the title
- For the statistics portion, I do recommend separate statistical review. While controlling for age
is very important for this study, I do believe that controlling for age in multivariate regression
analysis would be a better approach.
Subgrouping based on age has decreased sample size and may explain lack of impact of BMI
in certain age groups
- Why did authors choose this duration of the study? why not including more years to increase
sample size. Did the authors calculate needed sample size?
- What about different stimulation protocols. These can impact outcomes and need to be
controlled for.
- In discussion section, avoid repeating parts from methods, results (dates of the study, number
of cycles and patients) these were previously mentioned
- Authors need to compare their findings to what is already published and explain any
discrepancies.
Title: Effects of body mass index on IVF outcomes in different age groups
Version: 4 Date: 15 May 2023
Reviewer:  Paola quellari
Reviewer's report:
The paragraph 3.1 is part of the epidemiological characteristics of the patient court. In  my
opinion it is to be included in the materials and methods.
In the Discussion: remove the second paragraph "According to..." untill "the period December
2019 and December 2021", it is not necessary to repeat.
In the Conclusions:
Don't repeat "age 30-38" in the first sentence.
Change the last sentence: "IVF/ICSI treatment at an appropriate age and under a normal BMI
would be the first way to ensure a pregnancy".
Limitations: This study is limited by its retrospective design and lower number of women in the
extreme BMI categories.
References:
Rafael F., Rodrigues MD,Bellver J, Canelas-Paia M., Garrido N., Garcia-Velasco JA, Soares
SR, Santos-Ribeiro S.:The combined effetc of BMI and age om ART outcomes. Hum Reprod.
2023 May 2;38(5):886-894.
Title: Effects of body mass index on IVF outcomes in different age groups
Version: 5 Date: 10 Jun 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: -The authors responded adequately to my comments and did the
necessary changes
- Revised manuscript represents an improvement from initial form and can be accepted for
publication
ADDITIONAL REQUESTS/SUGGESTIONS:
-Minor writing issues (Affiliated should be affiliated with small a)
Last paragraph before conclusion (Finally, This should by this with small t)
- I believe the authors need to mention in the limitation section that different stimulation
protocols were used, however, they believe that should have minimum of effects on the results
since no difference was observed in dosage and days of Gn
Title: Effects of body mass index on IVF outcomes in different age groups
Version: 6 Date: 10 Jul 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses one or several
testable research questions? (Brief or other article types: is there a clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient technical rigor to
allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your concerns sufficiently
for you to now recommend the work as a technically sound contribution? If not, can further
revisions be made to make the work technically sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: The authors have responded adequately to my comments
The authors have made necessary changes
The manuscript is now acceptable for publication
Title: Effects of body mass index on IVF outcomes in different age groups
Version: 6 Date: 10 Jul 2023
Reviewer's report:
The manuscript is regarded as a valid and  conforms to the established standards. demonstrates
its suitability and acceptability within the given context., presents a systematic progression of
ideas, facilitating a logical flow and enabling a comprehensive understanding of the subject
matter. Its meticulous arrangement and coherent presentation enhance the clarity and readability
of the content, thereby fulfilling the requirements expected in an academic setting and accsepted.
Title: Examining the Influence of Mother-in-law on Family Planning Use in South Asia: Insights
from Bangladesh, India, Nepal, and Pakistan
Version: 0 Date: 07 May 2023
Reviewer's report:
• Please provide citation for the very first line of the introduction.
• On page 5 in the statement “In India, the MIL decides on the modern-limiting method of
contraception of DIL but not in respect of the modern spacing method of contraception” Is not
clear? Do authors want to say MIL influences limiting behavior but not spacing? If they are,
then it is not clear with the current statement.
• It would be nice if in the starting readers are given the list of countries that authors are talking
about within south Asia region.
• In the last para of the introduction section please provide citation for the statement “The role
of the family in influencing women's health and health-seeking behavior is, thus, undergoing
significant changes, owing to higher education, media exposure, and numerous government
initiatives, in addition to women's enhanced agency across South Asia”.
• “Of the total women, a majority were living with a husband and/or unmarried child(ren) in
India (49%),..” the statement is not clear.
• “In Nepal, women co-residing with the MIL have a higher chance of using contraceptive
methods…” which method?
• Its written in the discussion “The results indicate that the community health workers could
convince the MILs to support the DIL's use of the spacing method.” How community health
workers are doing this? In their national plan is there any vertical focused on MIL? If there is
then please elaborate on that.
• The comparison between this paper findings and other papers for example from Bangladesh
it would be reasonable only if the sample characteristics are same? If not then it’s better to also
give details of earlier findings by group characteristics.
• The paper says “The use of the traditional method of contraception may be due to less access
and knowledge about the modern spacing method” I think traditional method use is higher in
India among educated women. Please check the figures from NFHS  report.
• The study in its discussion says “Thus, there is a need to strengthen country-specific
family planning programs to ensure informed contraceptive choice in an enabling household
environment…” So, what is their country specific recommendation given that they have done
country specific analysis.
• I feel the paper has strength but the discussion can be written in more comprehensive way to
show country specific differences. And the interpretation of MILs effect is lost somewhere in
the discussion. There should be one para concluding MILs influence and then recommendations
based on it.
Title: Examining the Influence of Mother-in-law on Family Planning Use in South Asia: Insights
from Bangladesh, India, Nepal, and Pakistan
Version: 0 Date: 15 May 2023
Reviewer's report:
This study deals with important issues of contraceptive use in selected South Asian countries.
The author deals with the very important aspects of contraceptive use by considering the
presence of MIL in the family, especially in the context of South Asian countries where the role
of the elderly in the family in general is very prominent. The issue becomes more important
in the context of MIL presence as it has a deep-rooted influence on decision-making regarding
health, reproductive health, nutrition, and food behaviours.
The authors have provided a reasonable analytical approach for addressing the issues. However,
there are few observations and suggestions for background, theoretical underpinning, and
research gaps, along with a lack of flow in the discussion of the study that can improve this study.
I recommend this manuscript for publication after addressing the following comments and
suggestions:
The authors have made numerous sweeping statements at the start of the article without
providing any references.
The author has mentioned that the South Asian countries are showing an increase in female
education and work participation rates, which is quite contradictory to the findings of Sonalde
Desai et al. 2019, where they have argued for a significant decline in female labour force
participation rates in recent years. Therefore, the author should provide any empirical evidence
for this statement or change it in accordance with the study quoted above.
The author has not carried out any robustness analysis by analysing a subsample of women with
any living son, which is one of the most important predictors of contraception use in this study
along with numerous other studies. The influence of MIL on the use of contraception has more
influence, especially in the case of having any living male children in the family.
The author has stated in their results that the highest odds of using modern spacing, limiting,
and any traditional method of contraception are among the families with a husband, other family
members, and MIL as compared to the families with a husband and unmarried children and
families with a husband, other family members, and MIL. The author should have made one
more category where family with husband, unmarried children, and MIL is residing so the
influence of MIL would emerge even after adjusting for the living son and the age and education
of the women. Similarly, the author has made a policy recommendation for greater reach at
MIIL for increasing the use of contraceptives, which is already higher. Therefore, the policy
recommendation should be considered more for families with husbands and other relatives,
excluding MIL, for greater outreach of contraceptive use in selected South Asian countries under
study.
Lastly, the authors have written a few paragraphs in the conclusion section that do not address
the findings and implications of their study "Awareness generation on the benefits of modern
spacing methods among MIL.............".
Title: Examining the Influence of Mother-in-law on Family Planning Use in South Asia: Insights
from Bangladesh, India, Nepal, and Pakistan
Version: 1 Date: 15 Jun 2023
Reviewer's report:
The revised manuscript has improved a lot, and I am recommending it for publication after
considering the few comments below.
1. The authors have revised the manuscript substantially and incorporated almost all the
suggestions. However, one thing I would like to reiterate again is that the analysis of robustness
has not been done yet. The author should make a subset of the analysis in which the religious
factor of the household should be considered as the main predctor for the use of contraception by
controlling the presence of MIL because religion might be playing a pivotal role in determining
the use of contraception, either in the presence of MIL or not.
2. Similarly, the author has not included a separate category of women who have achieved their
desired family composition, which again plays a greater role than the presence of MIL in the
family in determining the use of contraception.
3. I am not sure regarding the availability of data on the education level of the MIL, which might
be a significant enabler for their role in the choice of contraception of their DIL. The author
should make a note of these factors as well.
4. In the discussion section, for Nepal's findings, the previous literature (i.e., reference 17) and
current findings are in similar directions. Therefore, the author should have some justification
for their findings.
5. The author has not revised the suggestions regarding the correlation of the basket of choices
of contraception that they have included in the study, and if this is the inference from other
studies, then the authors should have put the reference for that (i.e., the second last paragraph
of the discussion).
Title: Examining the Influence of Mother-in-law on Family Planning Use in South Asia: Insights
from Bangladesh, India, Nepal, and Pakistan
Version: 1 Date: 20 Jun 2023
Reviewer's report:
1. The statement added by authors in the discussion... “while a qualitative explorative study
found married adolescents are less likely to use contraception if MIL is against contraception
use” is exactly why I suggested to be cautious about the comparisons you make. It’s known fact
than in these countries proving fertility is very important in younger ages so as soon as you get
married you have the pressure to conceive. The study cited here maybe talks about the same
issue. The authors can try to look for MILs effect in different age groups.
2. These general recommendations “Nevertheless, the use of the modern spacing method is
dominated by contraceptive pills [30] in the country, thus, efforts to ensure informed choice in
contraceptive choice is needed. A recent study based on quantitative post-service exit survey
coupled with observations of the interactions between 62 Family Welfare Assistants (FWA)
and 692 female clients found only 20% of clients received adequate information for informed
decisions, 81% of clients who preferred a pill received it, while only 34% of clients seeking
long-acting methods received needed referrals [33]. Moreover, expanding the basket of choice
to the contraceptive users and specifically long-acting reversable methods may also be useful in
addressing the contraceptive choice of the women.” are good but nowhere related to the study
findings. The study is about MILs role in FP use not quality of care. It is suggested to cut this
and provide recommendation based on your findings.
3. Again, when authors state this “As women co-residing with MIL are less likely to use modern
spacing methods, there is a need to include the MIL in the existing FP program. This may be done
through the grassroot-level health workers like ASHA (Accredited Social Health Activist) as part
of their regular household visits and community interaction meetings.” It gives the impact that
there is no program involving MILs. Infact whatever is recommended here is already identified
and implemented as authors also mention in the next statement. These recommendations are
general and redundant. Please go through the program read papers on its evaluation and then
bring new facts to the discussion.
The manuscript has improved considerably yet I feel there is room for improvement in the
discussion. The discussion should be rephrased .
Title: The crucial value of serum ferritin in assessing high-risk factors and prognosis for patients
with endometrial carcinoma
Version: 1 Date: 30 Nov 2022
Reviewer:  Salvatore Insinga
Reviewer's report:
I read with great interest the Manuscript titled “The crucial value of serum ferritin in assessing
high-risk factors and prognosis for patients with endometrial carcinoma”, which falls within the
aim of this Journal.
In my honest opinion, the topic is interesting enough to attract the readers’ attention.
Methodology is accurate and conclusions are supported by the data analysis. Nevertheless,
authors should clarify some point and improve the discussion citing relevant and novel key
articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be further revised by a native English speaker.
- In the Results section, the Authors have simply reported the p values, from which however it
is not possible to deduce the real clinical relevance of the highlighted statistical significance. In
order to better understand the obtained results, I suggest reporting not only the p values, but also
the corresponding confidence intervals
- Does this manuscript conform the Enhancing the QUAlity and Transparency Of health
Research (EQUATOR) network guidelines? It would be mandatory to declare about this
element.
- Was this study registered? I could not find any information about this point.
- I could not find any information regarding the approval of the Institutional Review Board. Did
author this approval before the study start?
- I could not find any information regarding the informed consent of enrolled patients. Did author
obtain informed consent for each patient? Conversely, this point may raise serious concern from
the ethical point of view.
- Accumulating evidence suggests the potential use of novel biomarkers for early diagnosis,
management, and to predict the prognosis of endometrial cancer patients. Authors may stress
this point, referring to: PMID: 34837130; PMID: 32462419.
Title: The crucial value of serum ferritin in assessing high-risk factors and prognosis for patients
with endometrial carcinoma
Version: 1 Date: 07 Dec 2022
Reviewer's report:
1- There are some odd data in the “SF raw Data” file. For instance: there is a 71-year-old patient
with recurrence and DFS= -1, or a 24-year-old patient with two times of pregnancies and eight
months of menstruation, etc. It seems the data are not precisely acquired and the analyses might
be performed incorrectly.
2- More explanation is needed regarding the role of Ferritin in the pathogenesis of cancer at
the molecular levels. Also, the related signaling pathways should be addressed to clarify the
importance of Ferritin as an indicting biomarker in cancer patients.
3- The inclusion/exclusion criteria lack the history of the dietary supplements containing Iron
and its derivatives that patients might have consumed. This factor could directly destruct this
research by increasing the blood titer of Ferritin.
Title: The crucial value of serum ferritin in assessing high-risk factors and prognosis for patients
with endometrial carcinoma
Version: 3 Date: 28 Mar 2023
Reviewer's report:
Although the authors' responses are somehow satisfactory but are not included in the main
manuscript as demanded. Therefore, before accepting this manuscript, the authors should add:
1- a brief explanation regarding the molecular signaling pathways in the "Introduction" part
indicating the importance of studying Ferritin in malignancies.
2- the lack of patients' history of iron supplement consumption as the limitation of this study.
There are many studies showing the significant effect of iron supplements on the increased level
of Ferritin. For instance:
Jalambo M, Karim N, Naser I, Sharif R. Effects of iron supplementation and nutrition
education on haemoglobin, ferritin and oxidative stress in iron-deficient female adolescents in
Palestine: randomized control trial. East Mediterr Health J. 2018 Jul 29;24(6):560-568. doi:
10.26719/2018.24.6.560. PMID: 30079951.