Reviewer’s report
Title: 
Multiple use applicator for vaginal tablets / vaginal inserts – compliance
verification and suitability studies
Version: 
1 
Date: 
29 May 2020
Reviewer's report:
This is an interesting series of studies assessing a multiple use vaginal tablet
applicator. 
There are a number of issues that need to be resolved prior to
considering the ms for publication.
1. 
At least in the US, vaginal tablets are referred to as inserts (according to the
US FDA). 
I am not sure about this in Europe but this should be assessed and if
found to be the case, the ms needs to be revised accordingly (it can be introduced
as a 'tablet' but thereafter called an insert).
2. 
The organization of the ms needs significant revision. 
For instance, there are
three separate experimental/methods sections. 
These need to be combined into a
single section. 
Likewise, there are separate results sections that need to be
combined into one section.
3. 
There is no information/demographics provided on the subjects in the usability
trial. 
Were the women all post-menopausal?
4. 
Details on the questions asked in the usability study should be provided.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
No
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the
authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you
recommend an additional statistical review?
If an additional statistical review is recommended, please specify what aspects
require further assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
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