Reviewer’s report
Title: 
Adenomyoepithelioma of the breast with prominent cystic changes: a case
report
Version: 
1 
Date: 
19 Apr 2021
Reviewer's report:
Thank you for the opportunity to review this manuscript, I have no COI to
disclose. 
The authors present an interesting case report of a 52 year old female that
presented with adenomyoepithelioma of the breast. This case is rare, and would
be interesting to report. The authors should revise their text for English errors.
Also, it would be nice if the authors could add some more information on the
treatment or follow-up they performed. 
Few suggestions:
Please change "Changs" to "changes" in the title and in text (I believe this is a
mistake). 
"Most of AME reported are solid, cystic or prominent…" Please change to
"Most of AME reported are solid, however cystic or prominent …"
"might be suspected in radiology." Change to "on imaging" (abstract and
conclusion) 
Please define AME at first mention in text (and not just in the abstract).
"According to the World Health Organization classification of tumors of the
breast in 2012, AME was classified as Epithelial-myoepithelial lesions" please
cite this sentence. 
Did the patients previously undergo any breast cancer screening? Please indicate
in text. 
Please indicate if the patient had any family history of breast cancer. 
"but ductal carcinoma of breast, adenoid cystic carcinoma, etc. had the same
imaging findings" please change to "but ductal carcinoma of breast, adenoid
cystic carcinoma could not be excluded."
"So we suggested that the patient should have MRI examination" please change
to "So we suggested that the patient undergo MRI examination".
"Because of the tumor could not be completely ruled out as breast cancer" please
change to "Since breast cancer could not be excluded". 
"the patient urged" > "the patient was urged".
Did the patient receive any further treatment? Please indicate in text. 
Was the patient followed-up later with any imaging or clinical visits? Please
indicate in text.
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