Title: Sexual dysfunction in women with genital warts: a cross sectional study
Version: 2 Date: 27 Feb 2025
Reviewer:  Giuseppe Caruso
Reviewer's report:
Comments to BMC R2
Abstract:
Original:
"Purpose This study was designed to evaluate sexual dysfunction and quality of life in females
with genital warts."
Correction:
"Purpose: This study aimed to evaluate sexual dysfunction and quality of life in women with
genital warts."
Original:
"100 Females were determined eligible for inclusion if they were between 18-45 years,
complaining of GWs for at least 3 months and had been in a stable marital relationship for the
past 6 months."
Correction:
"A total of 100 women were included if they were aged 18–45 years, had genital warts (GWs)
for at least three months, and were in a stable marital relationship for at least six months."
Original:
"All women were interviewed to answer Female Sexual Function Index (FSFI) questionnaire
as well as a Dermatology Life Quality Index (DLQI) questionnaire Results The sexual
function domains showed the lowest mean scores to be related to orgasm (1.91±1.07), arousal
(2.82±1.12), satisfaction (3.01±1.01), pain (3.11±1.34), desire (3.37±1.01), and lubrication
(3.64±1.32)."
Correction:
"All participants completed the Female Sexual Function Index (FSFI) and the Dermatology
Life Quality Index (DLQI) questionnaires. Results showed that the lowest mean scores were
observed in the domains of orgasm (1.91±1.07), arousal (2.82±1.12), satisfaction (3.01±1.01),
pain (3.11±1.34), desire (3.37±1.01), and lubrication (3.64±1.32)."
Original:
"Sexual health and dysfunction and their impact on quality of life should be part of the integral
routine investigation for females complaining of genital warts."
Correction:
"Sexual health and dysfunction should be routinely assessed in women presenting with genital
warts."
Introduction:
Original:
"Genital warts caused by HPV have a worldwide annual prevalence of 160-289 per 100,000
persons with a peak age incidence of 25-29 years in men and 20-24 years in women."
Correction:
"Genital warts, caused by human papillomavirus (HPV), have a global annual prevalence of
160–289 per 100,000 individuals, with peak incidence occurring at ages 25–29 years in men
and 20–24 years in women."
Original:
"Concerns about the spread of lesions or recurrence of lesions, fear of transmitting the disease
to the spouse, worry about the spouse’s infidelity, lack of sufficient sexual knowledge and
skills, mental conflict, confusion and restlessness after diagnosis, are among the reasons for the
decrease in sexual desire, arousal, and orgasm in women with GWs."
Correction:
"Factors contributing to decreased sexual desire, arousal, and orgasm in women with genital
warts include concerns about lesion recurrence, fear of transmission, anxiety about spousal
infidelity, lack of sexual knowledge, and psychological distress following diagnosis."
Methods:
Original:
"The whole cross sectional study was designed and approved by the local ethics committee and
the institutional research board (IRB)."
Correction:
"This cross-sectional study was approved by the local ethics committee and the institutional
review board (IRB)."
Original:
"Confidentiality and personal privacy were respected in all levels of the study and Collected
data were not be used for any other purposes."
Correction:
"Confidentiality was maintained throughout the study, and collected data were used solely for
research purposes."
Results:
Original:
"The mean of age of participants was 32.5 ± 7.5 years, with disease duration of 20.03±10.39
months and a mean duration of marriage for 4.87±2.48 years."
Correction:
"The mean age of participants was 32.5 ± 7.5 years, with a mean disease duration of 20.03 ±
10.39 months and a mean marriage duration of 4.87 ± 2.48 years."
Discussion & Conclusion:
Original:
"In conclusion; we have observed a significant association between GWs and lower FSFI scores
in women."
Correction:
"In conclusion, a significant association was observed between genital warts and lower FSFI
scores in women."
Original:
"Further research is advised on diverse population."
Correction:
"Further research is recommended in diverse populations."
Limitations to Address:
- Absence of a Control Group: the study lacks a comparative group of women without genital
warts, limiting the ability to assess the direct impact of GWs.
- Small Sample Size: a larger sample would improve generalizability.