Reviewer ’s report  
 
Title: Clinical Characteristics of Genital Chlamydia Infection in Pelvic Inflammatory Disease  
 
Version: 0 Date: 14 Nov 2016  
 
Reviewer: V. Laxmi Yeruva  
 
Reviewer's report:  
 
The study was carried out with medical records of 497 women and the patients were divided into 
PID with and without chlamydia infection.  The ESR, C -RP and CA -125 were higher in 
chlamydia group than the non -chlamydia group. Authors claim that CA -125 levels  were 
strongest predictor of chlamydial infection then ESR and CRP.  
 
Comments:  
1. The study is not very novel, several researchers have done similar measurements with and 
without the chlamydia groups. Authors need to discuss what others have found and if it 
differs from the data they obtained.  Discuss how their data fits with literature.  
2. Page no 4, line 25 - 27 sentences are not true.   
3. It is not clear if the PID patient has prior STI history and if it is chlamydia or other 
infections.  How could one  conclude that PID is a result of only Chlamydia infection?  
4. It is recommended that statistical correlation analyses be done to make the associations 
(page 10, line 184 -186).  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supporte d by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please spec ify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please co mplete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publication of  this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently app lying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other fi nancial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give deta ils below.  
 
No 
 
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