JerMa88/BMC_Womens_Health_Peer_Reviews huggingface dataset:
Title: Outcomes of ovarian transposition in cervical cancer; an updated meta-analysis
Version: 2 Date: 27 Mar 2022
Reviewer's report:
This is the an interesting meta-analysis of the ovarian transposition efficacy and safety in cervical
cancer patients. In total, 1160 women with cervical cancer reported in 29 primary studies were
included in the current meta-analysis. There are several suggestions listed below:
1. It was mentioned that the proportion ovarian function preservation in Groups A-C was
91%,93% and 61%, however, there is no illustrations on how to monitor the preservation of
ovarian function.
2. In the Results section, 428 patients were in Group A, 143 in Group B and 321 patients in
Group C. however in the paragraph of “Preserved ovarian function”, I assume there were 435
patients in Group A, 107 in Group B and 512 in Group C according to the manuscript. I am a
little confused about the patients numbers or are there other explanations?
3. The variation across studies was significant in the 17 studies for ovarian cyst formation
analysis in Group A. What is the possible reasons for this variation?
Title: Outcomes of ovarian transposition in cervical cancer; an updated meta-analysis
Version: 2 Date: 08 Apr 2022
Reviewer:  T. Surappa Shylasree
Reviewer's report:
1. The incidence of ovarian cysts should be compared to background risk of ovarian cysts
in similar age groups in literature.  Incidental versus symptomatic cysts and cysts needing
intervention should be emphasized as these patients have more follow-up scan for cancer. and
incidental diagnosis is common. So there is a lag time effect of diagnosis of cysts compared to
general population .
2. Literature on the increase in all cause mortality of removing ovaries in premenopausal women
should be quoted as it has huge impact on conserving ovaries.
3. Extent of radiation outside the pelvic brim has implications to ovarian survival. If the data is
available on this , it can be incorporated.  Adjuvant brachy therapy alone is not the standard of
care in postop cervix, so separate analysis of this group might not have great impact on clinical
decision making. Radiotherapy group with a sub analysis  of brachy would have been sufficient.
To keep in mind for next update of this review in future.
4.  Transposing  and securing  the ovaries 2-3 cms above the umbilicus is good clinical practice
to reduce radiation effects. Route of surgery (MIS is better)  has an implication to how high you
can keep the ovaries. In post LACC era all cases will be done by open surgery. so next review
should consider this as a variable for survival of ovaries!!! it can be mentioned in the discussion
as its a relevant clinical point.
5. Authors have emphasized on fertility preservation largely, however highest burden of cervical
cancer is in young women who have completed family  in LMICs. Exogenous HRT is not
economically viably and non compliance is an issue. hence equal importance for hormone
preservation along with reporductive outcomes should be discussed in the meta analysis.
6. Since ovarian function, cysts and metastasis are time dependent variable, using proportions
alone without consideration of time especially with studies using heterogenous follow duration,
using non time dependent statistics might not be appropriate. Qualitative review of heterogeneity
is needed to understand the differences in seletion criteria, assesment tools, endpoints and
followup.
7. To provide funnel plot
8. Discussion should state the number of studies and patients added with respect to the authors
2014 meta analysis on the same subject.
9. Meta analysis by Buonomo B, Multinu F on ovarian transposition in patients in cervical cancer
prior to pelvic radiotherapy: a systematic review in int J gynecological cancer 2021 march 31(3):
360-370 should be quoted.
Title: Outcomes of ovarian transposition in cervical cancer; an updated meta-analysis
Version: 4 Date: 09 May 2022
Reviewer's report:
Thanks for the response from authors. However, I am still confusing about the patients number
in each Group. Maybe I misunderstood. However, if I understand correctly, there were 428
patients in Group A  in total,  as  mentioned in the response from the authors "The latter are
referring to Group A in the preserved ovarian function section. ", I assume the number (the
latter)of patients who reserved ovarian function  in Group A  should be less than the total number
of Group A(n=428).
Please make it clear.
Title: Outcomes of ovarian transposition in cervical cancer; an updated meta-analysis
Version: 4 Date: 05 Jun 2022
Reviewer's report:
This is a well written paper on a very important topic. Though cervical cancer is rare, it does
affect a proportion of young women where retaining ovarian function for fertility or hormonal
function is important. The authors have covered  all aspects surrounding this and future concerns
that may arise. I feel this paper can be accepted in its current format.
Title: Prevalence and associated factors of early sexual initiation among female youth in East
Africa: Further analysis of recent demographic and health survey
Version: 4 Date: 29 Jun 2022
Reviewer:  Monica Ewomazino Akokuwebe
Reviewer's report:
The authors' revised paper is accepted for acceptance as I recommended. The authors carefully
work and revised the papers serially with all the necessary information. I strongly recommend
the paper is accepted in your highly esteemed journal. This topic is highly significant in African
research and we should not down play it.
Thank you.
Warm Regards,
Monica Ewomazino Akokuwebe, PhD
Title: Prevalence and associated factors of early sexual initiation among female youth in East
Africa: Further analysis of recent demographic and health survey
Version: 4 Date: 07 Jul 2022
Reviewer's report:
The manuscript improved a lot, but still it needs a great detail discussion. Here  the following
are some minor comments.
1. “. If data is missing for more than 60% of the observations” would you cite it and state in
the word documents?
2. . “When does we say “…early sexual initiation becomes significant public health issue?” still
you didn’t get the point, when we say this? How much prevalence needed to say it?
3. Line 225 “This study showed that early sexual initiation was among youth in East Africa”.
Something missed on it
4. Your comment reply would not be copy and pasted.
Title: Prevalence and associated factors of early sexual initiation among female youth in East
Africa: Further analysis of recent demographic and health survey
Version: 5 Date: 11 Jul 2022
Reviewer:  Monica Ewomazino Akokuwebe
Reviewer's report:
Reviewer 1 Comments:
This is a topical and significant issue plaguing the youths to date, despite all efforts and
interventions created to address this menace. I hope the author(s) take the comments seriously
and work on them to make the paper come out beautiful.
Final comment: Accepted for publication with minor revisions
Minor Comments
1. Add more literature to the background of the study
2. Add the global prevalence of sexual initiation among female youth and also the prevalence
of countries across Africa with references
3. Needs professional editing
4. See all other comments inserted in the main manuscript saved with the name: ‘Revised
Manuscript’
OPTIONAL
I was expecting to see another table on bivariate analysis to show the significant associations
between the outcome variable and the explanatory variables so that the significant variables can
be analyzed in the multivariate (OPTIONAL FOR THE AUTHOR(S) TO INCLUDE)
Title: Prevalence and associated factors of early sexual initiation among female youth in East
Africa: Further analysis of recent demographic and health survey
Version: 5 Date: 17 Jul 2022
Reviewer's report:
A lot of comments are addressed , but still I have some concerns
1. High prevalence is not mean public health concern, if you no evidence for a cutoff criterion
for saying public health concern, you should say only high.
2. Line 28….to estimate the pooled prevalence and associated factors…correct as “to estimate
the pooled prevalence and to identify associated factors..”
3. “Awareness on the negative consequences of early sexual beginning are among the
contextually relevant solutions.” is not the proper recommendation, because you have done
a research on the factors of early sexual initiation, so you have to point out you suggestion/
recommendation about how to increase /decrease this factor to get good result.
Title: Effectiveness of Resilience Training Intervention on Psychological Capital of the
Underprivileged Widowed Women of Fasa City, Iran
Version: 5 Date: 03 Jun 2022
Reviewer's report:
1.need to add exact p value and not only 0.05
2.table 2, 3 in the cell above mentioned student's t test and in the table legends mentioned paired
t test which one used ?
Title: Effectiveness of Resilience Training Intervention on Psychological Capital of the
Underprivileged Widowed Women of Fasa City, Iran
Version: 9 Date: 29 Jun 2022
Reviewer's report:
In my opinion, the article can be accepted. I have only one suggestion. Due to the similarity
of the subject and the content of the article, I suggest you to use the following article in the
introduction and discussion section
Title: Determinants of Pelvic Organ Prolapse at Public Hospitals in Hawassa City, Southern
Ethiopia, 2020: Unmatched Case Control Study
Version: 4 Date: 08 May 2022
Reviewer:  Giulia Zaccaria
Reviewer's report:
I read with great interest the Manuscript titled “"Determinants of Pelvic Organ Prolapse at
Public Hospitals in Hawassa City, Southern Ethiopia, 2020: Unmatched Case Control Study" (ID
579a6499-930e-4715-9c44-06df4df7a430, which falls within the aim of this Journal. In my
honest opinion, the topic is interesting enough to attract the readers’ attention. Methodology is
accurate and conclusions are supported by the data analysis. Nevertheless, authors should clarify
some point and improve the discussion citing relevant and novel key articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be further revised by a native English speaker
- Inclusion/exclusion criteria should be better clarified.
- What are the actual clinical implications of this study? it is important to report the results
obtained by the authors in the context of clinical practice and to adequately highlight what
contribution this study adds to the literature already existing on the topic and to future study
perspectives
- Does this manuscript conform the Enhancing the QUAlity and Transparency Of health
Research (EQUATOR) network guidelines? It would be mandatory to declare about this
element.
- Was this study registered? I could not find any information about this point.
- Among POP, cystocele represents of the most challenging condition: the prolapse of anterior
compartment, indeed, could be treated by both prosthetic surgery and native tissue repair. I
suggest to discuss pro and cons of these two approaches, referring to: PMID: 33813235; PMID:
26801794.
Title: OBSTETRIC VIOLENCE AND DISABILITY OVERLAPS: OBSTETRIC VIOLENCE
DURING CHILD BIRTH AMONG WOMEN WITH DISABILITIES. A QUALITATIVE
STUDY
Version: 2 Date: 08 Jun 2022
Reviewer:  Pietro Serra
Reviewer's report:
I read with great interest the Manuscript titled “Obstetric violence and disability overlaps
obstetric violence during child birth among women with disabilities. A qualitative
study” (c4d1558d-6b8e-4bd2-ad86-a8a913a7cb33), which falls within the aim of this Journal.
In my honest opinion, the topic is interesting enough to attract the readers’ attention.
Nevertheless, authors should clarify some point and improve the discussion citing relevant and
novel key articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be further revised by a native English speaker.
- Inclusion/exclusion criteria should be better clarified.
- What are the actual clinical implications of this study? it is important to report the results
obtained by the authors in the context of clinical practice and to adequately highlight what
contribution this study adds to the literature already existing on the topic and to future study
perspectives.
- Does this manuscript conform the Enhancing the QUAlity and Transparency Of health
Research (EQUATOR) network guidelines? It would be mandatory to declare about this element
- I suggest to discuss, at least briefly, the risk factors associated with adverse fetal outcomes in
pregnancies affected by Covid-19 (authors may refer to: PMID: 32975205; PMID: 32926494).
- I recommend to highlight the potential detrimental effects of being a migrant female patient in
a foreign Country (authors may refer to:  PMID: 25444613).
Title: OBSTETRIC VIOLENCE AND DISABILITY OVERLAPS: OBSTETRIC VIOLENCE
DURING CHILD BIRTH AMONG WOMEN WITH DISABILITIES. A QUALITATIVE
STUDY
Version: 2 Date: 18 Jun 2022
Reviewer:  Erika Catania
Reviewer's report:
I read with great interest the Manuscript titled “OBSTETRIC VIOLENCE AND DISABILITY
OVERLAPS: OBSTETRIC VIOLENCE DURING CHILD BIRTH AMONG WOMEN WITH
DISABILITIES. A QUALITATIVE STUDY ” (c4d1558d-6b8e-4bd2-ad86-a8a913a7cb33),
which falls within the aim of this Journal.
In my honest opinion, the topic is interesting enough to attract the readers’ attention.
Methodology is accurate and conclusions are supported by the data analysis. Nevertheless,
authors should clarify some point and improve the discussion citing relevant and novel key
articles about the topic.
Authors should consider the following recommendations:
- Manuscript should be further revised by a native English speaker.
- Inclusion/exclusion criteria should be better clarified.
- Does this manuscript conform the Enhancing the QUAlity and Transparency Of health
Research (EQUATOR) network guidelines? It would be mandatory to declare about this
element.
- Was this study registered? I could not find any information about this point.
- I could not find any information regarding the approval of the Institutional Review Board. Did
author this approval before the study start?
Title: The Effect of Video-Based Multimedia Training on Knowledge, Attitude, and
Performance in Breast Self-Examination
Version: 2 Date: 25 Apr 2022
Reviewer:  Fatemeh Darabi
Reviewer's report:
Items that need to be corrected are mentioned in methane.
By performing printable reform
Correct the title:
The effect of educational intervention ..........: Based on the use of technology for women's health
There is only no meaningful enough for each of the variables to write mean and standard
deviation
In the comparison results section between the results of the variables mention
Note the time of implementation of educational intervention and post -test period
The number of keywords is too limited
Be matched with mesh
It is better to talk about chronic diseases at the beginning of the sentence, and it is said that
cancers have this percentage of this percentage of cancer.
And first this figure in the world and then in Iran
In the Introduction, other similar studies have not been addressed and mentioned their results
Describe the application of research
More important the importance of the matter in Iran
It is better to write at the beginning of the work on samples and how to sample and then the
arrival criteria and the kitchen
Is it enough for 2 hours? Is it based on a reference?
List your educational strategies
Talk more about the educational intervention program and how to run in groups
in table 3 Below this section write the average and standard deviation
in discussion Same studies in this field
It is better to use their justification for all aspects.
The reason for this relationship is why these results have been achieved in your study?
Write the strengths and weaknesses of the study.
Write the study limitations
Mention suggestions for other studies
Title: The Effect of Video-Based Multimedia Training on Knowledge, Attitude, and
Performance in Breast Self-Examination
Version: 2 Date: 13 May 2022
Reviewer's report:
Thank you very much for the interesting paper.
I believe it needs many revisions:
- INTRODUCTION:
-- Too much data about the epidemiology of breast cancer, and some are wrong. We do not have
stage 5 BC, the last is stage 4. Also, the data begin with BC in Iran, but it then says than 1 in
8 women gets BC, which is only correct in areas where the incidence of BC is very high, like
the USA or the UK.
-- The meaning of this sentence is not clear, and the data is not correct. The authors should
consult a clinician in order to correct this sentence and many other sentences which contain
clinical data:  "There can be a diverse range of diagnoses from Breast Self-Examination (BSE) to
regular screening, by healthcare professionals such as mammography, and sonography (9, 19). "
-- The authors say: "However, breast screening expenses are very high in Iran.". However, there
is no formal breast cancer screening program in Iran.
-- BSE is written SBE in some places
-- The authors say:" there is a  financial cost due to the unnecessary screening referrals in Iran,
which can be prevented by enhancing alternatives such as SBE". This needs to be investigated.
Studies in other countries has not shown that BSE can replace BC screening my mammography
and clinical breast exam, but it is possible that BSE could be cost effective. However this has not
been studied, especially in Iran, and one cannot say that BSE can effectively prevent unnecessary
screening costs.
- METHODS:
-- Who prepared the videos contents? Who confirmed their suitability, or how were they
validated as suitable? What did they include?
-- How was the performance of participants assessed? This cannot be assessed via questions or
questionnaires?
-LIMITATIONS:
-- One of the limitations is the lack of evaluation of the BSE screening behavior of the women
before and after the test.
-OVERALL:
- The article has several typos
- The English language needs serious editing
Title: Considerations for multimodal prehabilitation in women with gynaecological cancers: A
scoping review using realist principles
Version: 1 Date: 27 Apr 2022
Reviewer's report:
The study presents a relevant topic in health care for women with gynaecological cancer. In
addition, the scoping review carried out the mapping of published studies on multimodality
interventions and presented the knowledge gaps that indicate the need for future studies.
Regarding the abstract, the authors need to correct the methods section, as the scoping review
did not include only qualitative articles and correct the sentence that refers to unimodal or
multimodal intervention, as the scoping review includes only multimodality interventions.
In the methodology:
- Justify the choice of databases.
- Gray literature bases are not presented in the text.
- Present the description of the abbreviations of the databases.
- Explain the process of removing duplicates.
- Justify the evaluation of qualitative studies.
- Which review steps used Covidence?
- How was the data categorized?
- Did the researchers use any instruments to extract the data?
- I suggest using the Preferred Reporting Items for Systematic reviews and Meta-Analyses
extension for Scoping Reviews (PRIMA-ScR).
In the results section, I suggest transforming the questions that are in the subheadings into
affirmative sentences.
Regarding figure 2, it is necessary to include in the text that the references of the selected
publications after the full reading were also considered for the inclusion of the publications.
About table 2, does the first column refer to the year of publication?
In table 3, one of the interventions cites the authors (Sarcopenia in surgical oncology patients
referred for rehabilitation).
Title: Considerations for multimodal prehabilitation in women with gynaecological cancers: A
scoping review using realist principles
Version: 3 Date: 26 May 2022
Reviewer's report:
Congratulations to the authors for the corrections. I believe that the information was presented
more clearly, especially with regard to the abstract, the justification for the review, the
description of the realistic synthesis, the inclusion criteria, the search strategy and the
presentation of the results. Also, I suggest full review to adjust formatting defaults.
I highlight some points that need review:
Introduction:
- I suggest inserting the last paragraph of the introduction (reference 14) as the first paragraph of
the methodology. This change underlies the reason why the authors opted for the scoping review.
Methodology:
- The exclusion criteria associated with social media posts, podcasts and blogs are not
understandable. The authors of the manuscript performed the search in databases and not in
social media.
- Step 7: Presentation of results: I suggest describing this step at the beginning of the results
section, it is duplicate information. Tables 2 and 3 and Figure 2 are explored only in the following
section.
Results:
- Page13Line305: review the sentence in yellow, it is not clear.
Title: Considerations for multimodal prehabilitation in women with gynaecological cancers: A
scoping review using realist principles
Version: 5 Date: 09 Jul 2022
Reviewer:  Thane Chambers
Reviewer's report:
Thank you for responding to my comments from the previous round of peer review. My concerns
have been addressed and I am glad to see that you have now included your full search strategy,
things are now making much more sense.
Title: RNA-seq reveals co-dysregulated circular RNAs in the adenomyosis eutopic
endometrium and endometrial-myometrial interface
Version: 0 Date: 08 Apr 2022
Reviewer's report:
In my onion, the paper is valuable, but some minor points should be reconsidered.
1. In the abstract and main text, please provide number of participants of the study and control
group.
2. data about all reagents and machines used in the experiment should be completed.
3. in the discussion, please add strength and limitation of this study
4. for example,  for this information please provide accession date (https://www.genome.jp/)
Title: RNA-seq reveals co-dysregulated circular RNAs in the adenomyosis eutopic
endometrium and endometrial-myometrial interface
Version: 0 Date: 05 May 2022
Reviewer's report:
This is an interesting original study, consistent with the scope of the journal. I have the following
comments/suggestions for the authors.
L71: cyclical uterine pain etc are different ‘types’ of symptoms rather than ‘degrees’.
Sample collection:
1. Please specify how you confirmed the presence/absence of AD in the different groups.
2. What was the reason for hysterectomy in the control group?
3. The uterine JZ is more of an MRI concept and has not been defined so well at the
histological level, given also the lack of a separating membrane between the tissues. So, to be
clear, by isolating the EMI do you mean that you retrieved the myometrium just beneath the
endometrium?
L147: Since sequencing-based results are widely believed to be sensitive to the RNA integrity
number (RIN), could you specify the values you obtained using the Bioanalyzer?
Discussion:
1. I would propose to extend a bit the discussion and focus more on AD. You should discuss
the importance of your findings in understanding the disease (how they correlate with previous
literature on the topic, what new they may reveal in terms of pathogenic mechanisms etc).
2. Did you find previously published evidence or do you have your own hypothesis regarding the
role of MAPK pathway (and other key pathways of fig. 6) dysregulation in AD pathogenesis?
For example, in line 301, it is mentioned that these pathways may be involved in endometriosis,
a closely related disease. Could you briefly explain how?
3. I would suggest that another very interesting finding is that 879 circRNAs were found
dysregulated in the subendometrial myometrium of AD patients, while the relevant number for
eutopic endometrium was only 64. Do you have any idea what biological functions are mainly
associated with these circRNAs? And could this result indicate that they myometrium plays the
primary role in disease development? Maybe worth discussing this matter a bit and in correlation
with previous findings in literature...