Reviewer ’s report  
 
Title: Association between the ERCC1 polymorphism and platinum -based chemotherapy 
effectiveness in ovarian cancer: a meta -analysis  
 
Version: 0 Date: 04 Apr 2016  
 
Reviewer: Xiao -Jian Yan  
 
Reviewer's report:  
 
Please refer to the follow ing common issues and take actions accordingly if necessary:  
1. This is a coherent article, and author has made a clearly description, what's more, the author 
had distinctly point out the limitations such as the lack of samples, the shortage of detailed 
individual data, and the existence of published bias.  
 
2. The who le article appears simplification, the valuable data are insufficient, and authors can 
make more subtype to analysis the relationship between the platinum -based chemotherapy 
effectiveness with the ERCC1 C19007T polymorphisms, not just compare the ethnicity . 
 
3. There are numerous spelling/grammar errors in the current version of the manuscript. Please 
correct them carefully and seek help from qualified colleagues or professional editing 
company if necessary.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required i n your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional s tatistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in t he past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisat ion that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursemen ts, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to t his paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests.  
 
I agree to the open peer review policy of  the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
responses. I a gree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal