Reviewer’s report
Title: 
Screening test accuracy of portable devices that can be used to perform
colposcopy for detecting CIN2+ in low- and middle-income countries: a
systematic review and meta-analysis
Version: 
0 
Date: 
21 Aug 2020
Reviewer: 
Gordana Kovacevic
Reviewer's report:
This systematic review analyzed diagnostic accuracy of portable devices used for
colposcopy in low- and middle- income countries (LMIC). Authors screened
1737 references and assessed 239 full-text articles for eligibility, out of that only
five single-gate DTA studies, with 2693 women involved, met the criteria
defined in accordance the review's aims.
Overall, I find that all parts of the manuscript are good. The aim of this study is
well defined. In course of the improvement of the quality of the work, I've
outlined some suggestions below:
1. Since the term "portable device" is mentioned in the title of the manuscript, I
suggest broader insight in portable devices used for colposcopy in section
Introduction.
2. In the Table 1, in row starting with "Newman 2019" 
I noticed a mismatch
between number of women receiving biopsy 27/488 (5.5%) and prevalence of
CIN2+ which is 31/488 (0.6%). If 27 women received biopsy, how CIN 2+ was
observed in 31 women? Please, check on all numbers and percentages in this
row.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes