Reviewer’s report
Title: 
Combination of pioglitazone and clomiphene citrate versus clomiphene
citrate alone for infertile women with the polycystic ovarian syndrome
Version: 
1 
Date: 
07 Apr 2021
Reviewer's report:
Dear Respectable Editor
Thank you to give me the opportunity to review the manuscript entitled
(Combine Pioglitazone and clomiphene citrate versus clomiphene in pregnancy
outcome in infertile women with PCOS).
Authors found although the number of follicles was higher in the pioglitazone
group. Ovary stimulation and pregnancy rate had no differences between the two
studied groups. Authors concluded that although the number of follicles was
higher in the pioglitazone group, there was no differences in ovary stimulation
and pregnancy rate.
Authors presented structured abstract in their article.
In the background, the authors mentioned the magnitude of anovulatory
infertility in PCOS women.
The authors mentioned in the methodology section the patients' selection, and
their interventions clearly. They specified the sample size, and the statistical
methods used to get their results. Results of the manuscript are clear.
In the discussion section, the authors compared their findings with others.
The authors conclusion is clear reflecting their results, and they used relevant
references. 
Finally, the manuscript can be accepted for publication without any suggested
changes from my side.
Regards
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes