Review for 10.1186/s12876-020-01585-5 (2021)

Reviewer’s report
Title: 
Application of Artificial Intelligence in Chronic Liver Diseases: A
Systematic Review and Meta-analysis
Version: 
0 
Date: 
02 Nov 2020
Reviewer's report:
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The manuscript systemic review the application of artificial intelligence in
chronic liver diseases. The idea of this paper is a good one, but there are many
changes that are needed.
1. This paper included studies with several image modalities such as CT, MRI
and elastography. I Know there is relatively few studies with if chose one image
modality, but study include all of them, whether the conclusion is valuable still
controversial. 
2. These studies didn't compare the performance of AI and human for staging
liver fibrosis and steatosis. We didn't Know if the AUROC of AI is better than
human. 
3. Please make sure the AUC for predicting cirrhosis, stage ≥F2 and ≥F3 fibrosis
4. Table 3 is easy to mislead the reader; the result of AI is not patients with
NAFLD. 
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
No
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
No
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes