Review for 10.1186/s12876-021-01898-z (2021)

Reviewer’s report
Title: 
Utility of the Narrow-band imaging International Colorectal
Endoscopic classification for optical diagnosis of colorectal polyp histology in
clinical practice: a retrospective study
Version: 
0 
Date: 
15 Apr 2021
Reviewer's report:
I have read with interest the manuscript entitled "Utility of the NICE
classification for endoscopic diagnosis of colorectal polyp histology in clinical
practice" by Hamada et al. This is a retrospective single-center study including
543 polyps to evaluate the performance of NICE classification for real-time
histological diagnosis. The subgroup analysis according to polyp size (<10 mm
and ≥10 mm) was also performed. Moreover, the inter-observer and intra-
observer agreements for expert and non-expert endoscopists were demonstrated.
The result of this study, as expected, was not different from previous studies.
Application of NBI with the use of NICE classification showed to have high
negative predictive values, not depends on the polyp size. The reproducibility
was excellent among experts but substantial for medical students. By all
accounts, I did not find any additional information provided by this study.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
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from apparent manipulation?
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