Review for 10.1186/s12876-021-01854-x (2021)

Reviewer’s report
Title: 
Successful use of montelukast in eosinophilic gastroenteritis: a case report
and a literature review
Version: 
0 
Date: 
01 Apr 2021
Reviewer's report:
I congratulate the authors on shedding light on this rare condition and exploring
ways to better manage these patients.
1. Did the patient have any joint pains or rashes? We know connective tissue
disorders may lead to systemic eosinophilia, this will be a pertinent negative
history to note.
2. Please also note if any lymphadenopathy was noted on cross sectional
imaging. Lymphoproliferative disorders are linked with eosinophilia.
3. How many eosinophils were seen per hpf? While there is no established
defined cutoff for diagnosis, usual acceptance is >50/hpf atleast.
4. Please elaborate followup course, how soon did the symptoms resolve? Was it
immediate, or gradual over weeks to months?
5. What are your plans on duration of monteleukast therapy?
6. Line 155, with lipase elevation and epigastric pain, you technically do not
need imaging findings to diagnose pancreatitis, better wording would be 'in
absence of typical pancreatitis related epigastric pain'.
7. Was thickened colonic wall evaluated with a colonoscopy? If not please
provide a rationale, was it due to patient declining workup? IBD is linked with
peripheral eosinophilia in upto 15-20% of patients, and can have a waxing and
waning course with spontaneous remission possible, can you be certain this was
not IBD with foregut involvement? Please comment.
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Is the study design appropriate to answer the research question (including the use
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