Review for 10.1186/s12876-020-01423-8 (2020)

Reviewer’ s report
Title: Small intestinal bacterial overgrowth as a cause of protracted wound healing and vitamin D
deficiency in a spinal cord injured patient with a sacral pressure sore: A case report
Version: 0Date: 11 Jul 2020
Reviewer's report:
Kubota Y et al. reported an exciting and educational case of a refractory sacral pressure sore which
healed after selective decontamination of the digestive tract (SDD; oral administration ofpolymyxin B sulfate and amphotericin B). Also, they speculated that malnutrition caused by smallintestinal bacterial overgrowth (SIBO) must be associated with intractableness of the pressuresore.
Major point
There is no evidence of recovery of SIBO after starting SDD1. Did the authors perform bacterial culture examination of gastrointestinal fluid again? Theyshould show additional blood test data after SDD including serum protein and albumin (nutritionstatus).
Minor point
1. Page 7. L 96. "sore" should be changed to "ulcer" and delete "[6]".2. Table 1. The value of eGFR may be wrong.3. Figure 1H. I can not recognize circumferential stenosis in this picture.4. Figure 1I. A jejunal ulcer can be seen in this picture.
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