Review for 10.1186/s12876-021-01762-0 (2021)

Reviewer’s report
Title: 
Acute surgical-like abdomen as a gastrointestinal manifestation of
COVID-19 infection: the first case report in Colombia.
Version: 
0 
Date: 
19 Feb 2021
Reviewer's report:
This is an interesting case report. However, he need some essential revisions. 
1) Although there are several articles on the topic (gastrointestinal symptoms,
acute abdomen in COVID-19 patients) few reference are reported and the
authors do not discuss some possible underlying mechanisms such as presence of
ACE-receptor in gastrointestinal tract, presence of SARS-CoV-2 RNA in the
stools with a potential oro-fecal transmission). The discussion and the
introduction need to be revised in the light of these features and new references
need to be added. As example:
a) Yang L, Tu L. Implications of gastrointestinal manifestations of COVID-19.
Lancet Gastroenterol Hepatol. 2020;5(7):629-630. doi:10.1016/S2468-
1253(20)30132-1
b) Varga Z, Flammer AJ, Steiger P, et al. Endothelial cell infection and
endotheliitis in COVID-19. Lancet. 2020 doi: 10.1016/S0140-6736(20)30937-5.
c) Bianco F, Ranieri AJ, Paterniti G, Pata F, Gallo G. Acute intestinal ischemia
in a patient with COVID-19. Tech Coloproctol. 2020;24(11):1217-1218.
doi:10.1007/s10151-020-02255-0
d) Zhang J, Garrett S, Sun J. Gastrointestinal symptoms, pathophysiology, and
treatment in COVID-19. Genes Dis. 2020 Sep 5. doi:
10.1016/j.gendis.2020.08.013. Epub ahead of print. PMID: 33521210; PMCID:
PMC7836435.
e)Gahide G, Frandon J, Vendrell JF. COVID-19 patients presenting with afebrile
acute abdominal pain. Clin Med (Lond). 2020 Apr 27;20(3):e4-6. doi:
10.7861/clinmed.2020-0150. Epub ahead of print. PMID: 32341078; PMCID:
PMC7354040.
f) Di Saverio S, Pata F, Gallo G, et al. Coronavirus pandemic and Colorectal
surgery: practical advice based on the Italian experience. Colorectal Dis. 2020
doi: 10.1111/codi.15056.
g) Buscarini E, Manfredi G, Brambilla G, Menozzi F, Londoni C, Alicante S,
Iiritano E, Romeo S, Pedaci M, Benelli G, Canetta C, La Piana G, Merli G,
Scartabellati A, Viganò G, Sfogliarini R, Melilli G, Assandri R, Cazzato D,
Rossi DS, Usai S, Tramacere I, Pellegata G, Lauria G. GI symptoms as early
signs of COVID-19 in hospitalised Italian patients. Gut. 2020 Aug;69(8):1547-
1548. doi: 10.1136/gutjnl-2020-321434. Epub 2020 May 14. PMID: 32409587;
PMCID: PMC7246093.
2) Luecocytosis: must be reported value and normal range under brackets, as
well as other raised blood values.
3) Please report the CRP value if available o report that CRP was not tested
4) English language must be improved. E.g. "with a Gram not suggestive 
of infection" or "The patient reentered the emergency room" sound not adequate
for an English reader. An translation service may be appropriate.
5) The image related to COVID-19 pneumonia is not acceptable. Please change
it with an CT image using the lung window to highlight the typical features of
COVID-19 pneumonia, using arrows to show the main findings
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