Review for 10.1186/s12876-020-01326-8 (2020)

Reviewer ’s report  
 
Title: Indications and diagnostic yield of small -bowel capsule endoscopy in a real -world setting  
 
Version: 0 Date: 27 Jan 2020  
 
Reviewer's report:  
 
Minor revisions:  
1. There were 27 patients excluded due  to reduced small bowel visualization and/or 
insufficient small bowel preparation. Do you have a objective criteria to evaluate the preparation 
of small bowel? Can you describe more detail how you definite "reduced" visualization and/or 
insufficient prepar ation?  
2. In your patients group, there were 210 known or suspected CD. Sometimes we perform 
capsule endoscopy in known CD patients for post treatment follow up, in that case, if the good 
treatment response (mucosal healing) decrease your SB -VCE positive f inding rate? Can you 
show more detail in the indications of CD patients? Is there any patient receive SB -VCE for post 
treatment follow up?  
3. In your 536 patients, none of capsule retention occurred. That's a good result, especially 
you have 210 CD patient s and you did not use patency capsule. Can you prescribe more detail 
about your SB -VCE protocol? Did you regular perform CTE/MRE to exclude possible stricture 
patients before SB -VCE?  
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments  to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the qualit y of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary f rom an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has ap plied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
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