Review for 10.1186/s12876-021-02013-y (2021)

Reviewer’s report
Title: 
“Stomach mass” as the first manifestation of IgG4-related disease : A case
report
Version: 
1 
Date: 
05 Sep 2021
Reviewer's report:
The clinical case is not presented in a well-organized way, starting from the chief
complaint and passing through the personal and family history, physical
examination and, then, the explanation of a logical and reasonable diagnostic
pathway. Despite the figures are interesting, the authors may have selected the
most important ones and actually have added a table summarizing the main and
general laboratory findings (in addition to IgD measurements), which are
completely missing. 
Indeed, a careful and precise case description is the basis of any case report,
regardless of the main aspect(s) that should support its publication or less.
Actually, another concern related to this manuscript, is that no fundamental and
practical take home message clearly emerges from this individual and isolated
case.
Finally, as an additional comment, the relationship/association between IgG4-
related disease and malignancies could have been discussed based on very recent
articles addressing this issues (see Rheumatol Ther. 2021 Sep;8(3):1207-1221.
doi: 10.1007/s40744-021-00326-8; World J Gastroenterol. 2021 Jul
7;27(25):3825-3836. doi: 10.3748/wjg.v27.i25.3825; Sci Rep. 2020 Mar
18;10(1):4910. doi: 10.1038/s41598-020-61585-z.)
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
No
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
No
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
No