Review for 10.1186/s12876-018-0808-9 (2018)

Reviewer ’s report  
 
Title:  Invasive inflammatory fibroid polyp of the stomach: A case report and literature review  
 
Version: 0 Date: 08 Oct 2017 
 
Reviewer:  Noam  Harpaz  
 
Reviewer’s report:  
 
This report describes a case of a deeply infiltrative gastric IFP with transmural invasion to the 
subserosa.  Although the tumor lacked some of the classical histological and molecula r features 
of IFP, the histology and the immunohistochemial profile are well -documented and reasonably 
convincing.  One would have liked to see negative DOG -1 immunostaining along with the other 
immunostains used to exclude GIST.  In addition, more detaile d documentation of the technical 
aspects of the PDGFRA testing are warranted.  
 
Although the phenomenon of infiltrative IFP is indeed rare, the authors neglected to discuss and 
cite prior reports of infiltrative IFP of the GI tract, most of which involved no n-gastric sites.  
Examples include an ileal IFP reported by S. Takimma and K. Koda (Gastroenterology Reports 
2016) and several earlier cases of invasive IFP cited within that report.  It is recommended that 
the Discussion and References be revised accordin gly. 
 
Are the methods appropria te and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusion s drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
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