Review for 10.1186/s12876-017-0608-7 (2017)

Reviewer ’s report  
 
Title: Telbivudine treatment started in early and middle pregnancy completely blocks HBV 
vertical transmission  
 
Version: 0 Date: 18 Sep 2016  
 
Reviewer: King -Wah Chiu  
 
Reviewer's report:  
 
A very interesting manuscript described Telibvudine play a major role for the prevention of 
vertical transmission of hepati tis B from mother to child.  
 
Major comments  
1. English revise is one of the critical concern on the current manuscript.  
2. Join table 1 and table 6 together to be the revised table 1  
3. Join table 2 and table 3 together to be the revised table 2 and addr ess the p value in it.  
4. Join table 4 and table 5 together to be the revised table 3 and address the p value in it.  
Are the methods appropriat e and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
Does the work include the necessary controls?  
 
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions dra wn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is r ecommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless  extensively edited  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this  manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied f or patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named report  
including any attachments I upload will be posted on the website along with the authors'  
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CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments  
which I do not wish to be included in my named report can be included as confidential comments  
to the editors, which will not be published.  
 
I agree to the open pee r review policy of the journal