Review for 10.1186/s12876-020-01365-1 (2020)

Reviewer’ s report
Title: The Alpha-fetoprotein Serum is still Reliable as a Biomarker for the Surveillance of
Hepatocellular Carcinoma in Indonesia
Version: 2Date: 30 Jun 2020
Reviewer's report:
The authors have answered the raised points correctly an I strongly believe the paper can be
published in the present form - however I am convinced that the conclusions drown hold true forsouth east Asia but not for the Western world. The authors stated correctly that this analysis holdstrue for Indonesia were the vast majority of the HCC cases are diagnosed in a advanced stage.
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Are the methods appropriate and well described?
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YesDoes the work include the necessary controls?
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YesAre the conclusions drawn adequately supported by the data shown?
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Yes
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additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statisticsQuality of written English
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Acceptable
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