Review for 10.1186/s12876-020-01238-7 (2020)

Reviewer’ s report
Title: Juvenile polyposis syndrome might be misdiagnosed as familial adenomatous polyposis: a
case report and literature review
Version: 0Date: 29 Dec 2019
Reviewer: Fabio Campos
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an
attachment. Please only upload as attachments annotated versions of manuscripts, graphs,supporting materials or other aspects of your report which cannot be included in a textformat.Please overwrite this text when adding your comments to the authors. It is difficult for apathologist to differentiate the juvenile polyps with dysplasia from adenoma. So, juvenile polypwith dysplasia can often be diagnosed asadenoma. (I don't agree with this idea, that should berevised with a pathologist)JPS patients with dysplasia, especially those with concomitantcolorectal adenocarcinoma, might be easily diagnosed with FAP. If dysplasia is found in a localarea of the background of multiple typical juvenile polyps, the diagnosis of JPS can be easilymade. I don't agree with the idea. Diagnosis of a Polyposis syndrome depends on many criteria(histological, endoscopic, topographic, etc)But if only few polyps were examined, they might bemisdiagnosed as adenomas, and the patient might be misdiagnosed with FAP. The presence ofmultiple pedunculated polyps and pathological examination of more polyps could help ensure anaccurate diagnosis. This is fundamental !!!!)
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Not relevant to this manuscript
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Needs some language corrections before being publishedDeclaration of competing interests
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