Review for 10.1186/s12876-021-01612-z (2021)

Reviewer’s report
Title: 
Dietary patterns and risk of non-alcoholic fatty liver disease
Version: 
0 
Date: 
08 Jun 2020
Reviewer's report:
- Introduction section: gut microbiota is an "invisible organ" of the human body
and vital for normal metabolism and immuno-modulation. The number and
diversity of microbes differ across the gastrointestinal tract from the mouth to the
anus, and is most abundant in the intestine. Since dysregulated gut microbiota is
an underlying pathological factor of NAFLD, it is a viable therapeutic target that
can be modulated by antibiotics, probiotics, prebiotics, synbiotics, fecal
microbiota transplantation, and microbial metabolites. In this way, is important
to report the role of microbiota changes and increased intestinal permeability
(PMID: 30221912; 32390701).
- Methods section: is possible to include data on the metabolic features
associated to NAFLD (i.e. insulin resistance, blood ipertension, lipid profile)?
Also is important to highlight the "traditional" diet pattern of Iranian population
- Discussion section: i suggest to underline the role of functional foods present in
traditional diet and its anti-oxidant and anti-inflammatory profile
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
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authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
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Yes
Are you able to assess any statistics in the manuscript or would you
recommend an additional statistical review?
If an additional statistical review is recommended, please specify what aspects
require further assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
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