Review for 10.1186/s12876-021-01731-7 (2021)

Reviewer’s report
Title: 
Oesophageal squamous cell carcinoma mimicking submucosal tumour
Version: 
1 
Date: 
03 Mar 2021
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
RELEVANCE - Does this case report make a contribution to medical
knowledge, have educational value, or highlight the need for a change in clinical
practice or diagnostic/prognostic approaches? 
Yes, this report contributes to medical knowledge
CASE DESCRIPTION - Are the details of the case sufficiently well described to
understand the patient's symptoms and course of treatment? 
Yes, the description of the case is sufficient
DIAGNOSIS/INTERPRETATION - Based on the facts presented, are the
diagnosis, interpretation, and course of treatment medically sound?
Yes, the work described is medically sound
DISCUSSION OF THE CASE - Does the discussion appropriately analyse the
importance of the findings and their relevance to future understanding of disease
processes, diagnosis or treatment? Has an adequate literature review pertinent to
the case been included?
Yes, the case is discussed fully in the context of the literature
OVERALL MANUSCRIPT POTENTIAL - Could an appropriately REVISED
version of this work represent a technically sound contribution?
Yes, this case report is suitable for publication
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: This is a very unique case report that was written in a
clear language. 
Overall, I feel that the authors deliver their message in a succinct
and clear fashion. 
I see that they have addressed the comments of the first
reviewer. The images are also contributing to the case report. 
I think that the case
report is ready to be submitted.
-- What did you find to be the major findings of the manuscript? They report a
unique presentation of squamous esophageal cancer . 
-- What unusual or novel methods does this paper use, if any? They did an
endoscopic resection. 
-- How does this work contribute to the field? As the authors mentioned, it is rare
for esophageal squamous cell cancer to present as a sub mucosal tumor. So this
is a rare finding.
-- How could other researchers use the information presented in this paper in
their own work? 
They could include this case as a possible way esophageal
cancer can present on endoscopy.
REQUESTED REVISIONS: 
Please see my comments above. I think the case report is mature enough to be
submitted.
ADDITIONAL REQUESTS/SUGGESTIONS: 
Not at this time.
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Declaration of competing interests
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes