Review for 10.1186/s12876-021-01876-5 (2021)

Reviewer’s report
Title: 
The onset of ulcerative colitis upon Helicobacter pylori eradication in a
72-year-old woman: Report of a rare case with a 3-year follow-up
Version: 
0 
Date: 
25 Apr 2021
Reviewer's report:
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Dear Authors,
Thank you for presenting this case. please answer my concerns and issuses:
1. there are some references which issues against this result. they consider
H.pylori eradication as a protective management in IBD especially crohn's. What
is your idea?
It beleive that, it would be great to adress 
some of them 
in your review.
2. how did you test for C.diff? different tests have different results, sensitivity
and positive predictive value.
3. As you mentioned, effect of medication, the patients autoimmune disease (
Hashimoto) and smoking could be significant confounders. How do you rule out
these confounders' effects?
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