Review for 10.1186/s12876-022-02319-5 (2022)

Reviewer’s report
Title: 
Oncologic outcome of colon cancer with perforation and obstruction
Version: 
1 
Date: 
12 Mar 2022
Reviewer's report:
Considering the rarity of simultaneous deficiencyof Mlh1 and MSH2, the
proportion of dMMR is high in the obstruction group. As well, there was a
relatively high frequency of KRAS mutation. These meaningful findings should
be included in the Results section. The method of Kras mutation detection
should be described.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
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Yes
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from apparent manipulation?
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