Review for 10.1186/s12876-020-01356-2 (2020)

Reviewer ’s report  
 
Title: Human translatability of the GAN diet -induced obese mouse model of non -alcoholic  
steatohepatitis  
 
Version: 0 Date: 30 Mar 2020  
 
Reviewer: Shahram Agah  
 
Reviewer's report:  
 
Please include all comments for the authors in this box rather than uploading your report as an 
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Thank you for well designed research.please consider that you performed liver biopsy as an 
invasive procedure in a 14 normal volunteer individual.How you consid ered the ethical issues 
and how do you consent them?  
 
I believe that 17 pages main article part is needed to be summarized,however, it depends on the 
journal regulations.  
 
Thank you again for precise work  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your commen ts to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects req uire further 
assessment in your comments to the editors.  
 
I recommend additional statistical review  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
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1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publi cation of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents  relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
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below. If your reply is yes to any, please give details below.  
 
'I declare that I have no competing interests' below.  
 
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I agree to the open peer review policy of the journ al