Review for 10.1186/s12876-019-1075-0 (2019)

Reviewer ’s report  
 
Title:  Association between serum IgG level and clinical course in primary sclerosing cholangitis  
 
Version: 1 Date: 01 Aug 2019 
 
Reviewer:  Karim  Hamesch  
 
Reviewer’s report:  
 
Congratulations to the nicely revised man uscript!  
 
Small comments:  
 
1) I would suggest small improvements to Figure 1  
 
- multiple: "diagnoSIS" (not "diagnose")  
 
- I would suggest to better visualize, that patient with biopsy/overlap are only part of the 
analyzed total cohort  
 
2) Figure 3: "Actuaria l" is a rather unusual term  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not,  please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
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6. Do you have any non -financial competing interests in relation to this paper?  
 
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