Review for 10.1186/s12876-017-0585-x (2017)

Reviewer ’s report  
 
Title:  Exceptional serological and radiological response to sorafenib in 2 patients with advanced 
hepatocellular carcinoma and chronic hepatitis C viral infection: Case report and review of the 
literature.  
 
Version: 0 Date: 06 Oct 2016 
 
Reviewer:  Michele  Tana  
 
Reviewer’s report:  
 
Interesting cases, and an important ad dition to the literature.  
 
"Response rate" should be defined in paragraph 2 of the Background.  
 
For Case 2, the diagnosis of cirrhosis should be clarified.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Unable to assess  
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in yo ur comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language co rrections before being published  
 
Declaration of competing interests  
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organisation that may in any way gain or lose financially from the publication of this 
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3. Do you hold or are you currently applying for any patents relating to the content of the 
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4. Have you received reimbursements, fees, funding, or salary from an organization that 
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5. Do you have any other financial competing interests?  
 
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below. If your reply is yes to any, please give details below.  
 
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