Review for 10.1186/s12876-020-01266-3 (2020)

Reviewer’ s report
Title: Pancreaticoduodenectomy for a primary duodenal capicua transcriptional repressor (CIC)
-rearranged sarcoma with severe bleeding: A case report
Version: 0Date: 13 Mar 2020
Reviewer: Gabriele Spoletini
Reviewer's report:
The topic is interesting and the limited availability of such cases in the literature makes it suitable
for publication.I have just a few minor comments:-Case presentation: the patient was initiallytreated endoscopically for GI bleeding from the tumor. It is not clear what was the plan for thepatient at that point? If this is not specified it feels like the patient was lost and represented only"by chance".-"The tumor had been exposed partially to the mucosal surface of the duodenum"should be rephrased, probably the Authors meant tumor invasion breached through the mucosa ofthe duodenum. -"Surgical margins were negative for tumor" I would add "for tumor invasion"-Wasthe tumor intact?-In discussion: "split evenly between" sounds quite informal and should bechanged-"could not be controlled by endoscopic hemostasis or intravascular embolization" there isno mention of a failed attempt at controlling bleeding with embolization. This should be eitheradded in the case presentation or erased from the discussion.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
YesAre the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
AcceptableDeclaration of competing interests
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