Review for 10.1186/s12876-022-02189-x (2022)

Reviewer’s report
Title: 
Undifferentiated high-grade pleomorphic sarcoma of the colon: A rare
case report and literature review
Version: 
0 
Date: 
19 Aug 2021
Reviewer's report:
The Manuscript titled - Undifferentiated high-grade pleomorphic sarcoma of the
colon: A rare case report and literature review, aims to report a rare case of high-
grade pleomorphic sarcoma of the large intestine. 
The manuscript attempts to deliver some important information, however, has
some major concerns which need addressing. 
1. The language of the manuscript could be improved which would increase the
readability of the published article. 
a. The sentence - 'The cause of UPS is still unknown. However, some
researchers proposed that some predisposing factors, such as genetics,
chemoradiotherapy stimulation, chronic irritation, and lymphedema, were
significantly correlated with the UPS occurrence' should be reframed to deliver
more diligent information. 
b. Page 2, line 50 - Besedes to be replaced by Besides
c. Page 3, line 19 - 'Medical history:' to be omitted. Please report as a complete
sentence 
d. Page 3, line 27,78 - the authors probably meant 'increased exhaustion' 
e. It might be more prudent to report in past tense - eg, 'The computed
tomographic scan showed bilateral pleural effusion, pericardial effusion, pelvic
fluid and irregularly thickened wall of the descending colon. 
f. The reporting should be done in the same tense - at places present tense is used
and at other places past tense has been used. 
g. Page 4, lines 51,52 - UPS rarely (replace hardly by rarely) occurs in the colon.
2. Page 3, lines 29,30,31 - Please report the physical examination more
objectively 
3. Page 4, line 59, 60 - Age of onset should be reported as range and referenced.
Reporting as mean is not prudent as this data is adopted from other studies. The
same holds true for the diameter of the lesion, range with median is a better
reporting method than mean with standard deviation 
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
No
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes