Review for 10.1186/s12876-020-01331-x (2020)

Reviewer’ s report
Title: Prevalence of non Helicobacter pylori gastric Helicobacters in Iranian dyspeptic patients
Version: 1Date: 05 Jun 2019
Reviewer: Jianzhong Zhang
Reviewer's report:
In this study, the authors observed the distribution of NHPGH in large samples of dyspepsia
population, especially in the light of local dietary characteristics. This study has certainsignificance for understanding the related factors of NHPGH infection and is valuable forpublication as basic data.However, there are two points that need to be modified properly by theauthor: 1. The frequencies of 10 suis，10 H. felis， 20 H. salomonis， 13 H heilimannii and 7 H.
bizzozeroni positive in 421 gastric biopsies form dyspeptic patients were relatively low and atthe nearly same lever. So, the " Conclusions— H. salomonis as the predominant NHPGH species
in Iranian dyspeptic patients." is inappropriate.2. Due to the limited number of NHPGH positivecases, it is necessary to be very careful in drawing the conclusion of disease-related analysis. It issuggested that "no obvious correlation is observed".
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
YesDoes the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
YesAre the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
NoAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statisticsQuality of written English
Please indicate the quality of language in the manuscript:
Acceptable
Declaration of competing interests
Please complete a declaration of competing interests, considering the following questions:
1. Have you in the past five years received reimbursements, fees, funding, or salary from an
organisation that may in any way gain or lose financially from the publication of thismanuscript, either now or in the future?
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose
financially from the publication of this manuscript, either now or in the future?
3. Do you hold or are you currently applying for any patents relating to the content of the
manuscript?
4. Have you received reimbursements, fees, funding, or salary from an organization that holds
or has applied for patents relating to the content of the manuscript?
5. Do you have any other financial competing interests?6. Do you have any non-financial competing interests in relation to this paper?
If you can answer no to all of the above, write 'I declare that I have no competing interests' below.
If your reply is yes to any, please give details below.
I declare that I have no competing interests.
I agree to the open peer review policy of the journal. I understand that my name will be included
on my report to the authors and, if the manuscript is accepted for publication, my named reportincluding any attachments I upload will be posted on the website along with the authors'responses. I agree for my report to be made available under an Open Access Creative CommonsCC-BY license (http://creativecommons.org/licenses/by/4.0/). I understand that any commentswhich I do not wish to be included in my named report can be included as confidential commentsto the editors, which will not be published.
I agree to the open peer review policy of the journal