Review for 10.1186/s12876-016-0560-y (2017)

Reviewer ’s report  
 
Title:  Relationship of Body Weigh t with Gastrointestinal Motor and Sensory Function: Studies 
in Anorexia Nervosa and Obesity  
 
Version: 0 Date:  27 Jun 2016 
 
Reviewer:  Askin  Erdogan  
 
Reviewer’s report:  
 
Dear Editor,  
 
I have reviewed the manuscript entitled "Relationship of Body Weight with Gastrointestinal 
Motor and Sensory Function: Studies in Anorexia Nervosa and Obesity."  
 
It is a well -written paper, and gives insights regarding the motor functional changes in patients 
with anorexia nervosa and obesity; as well as changes after diet modification for anorexia 
nervosa. I have some questions as given below.  
 
 
Yours sincerely,  
 
 
 
1. Did muffins contain lactose? Please give more information  
 
2. Were patients tested for lactose intolerance?  
 
3. Could the symptoms of for example satiety etc. be related to existing lactose intolerance 
especially in patients with AN?  
 
4. Patients were not  tested for SIBO, this needs to be stated in the study.  
 
5. Please give more details for lactose breath testing; i.e: The frequency and the length of 
breath sampling.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls ar e required in your comments to the authors.  
 
Yes 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you rec ommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I recommend additional statistical review  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication o f this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied  for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I h ave no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing in terests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I agree for my report to be made available under an Open Access Creative Commons  
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be included in my named report can be included as confidential comments 
to the editors, which will not be published . 
 
I agree to the open peer review policy of the journal