Review for 10.1186/s12876-022-02463-y (2022)

Reviewer’s report
Title: 
Response to Chemotherapy Combined with Anlotinib Plus Anlotinib
Maintenance in Intra-abdominal Desmoplastic Small Round Cell Tumors
(IADSRCT): A Case report and literature review
Version: 
0 
Date: 
06 May 2022
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
RELEVANCE - Does this case report make a contribution to medical
knowledge, have educational value, or highlight the need for a change in clinical
practice or diagnostic/prognostic approaches? 
Yes, this report contributes to medical knowledge
CASE DESCRIPTION - Are the details of the case sufficiently well described to
understand the patient's symptoms and course of treatment? 
Yes, the description of the case is sufficient
DIAGNOSIS/INTERPRETATION - Based on the facts presented, are the
diagnosis, interpretation, and course of treatment medically sound?
Yes, the work described is medically sound
DISCUSSION OF THE CASE - Does the discussion appropriately analyse the
importance of the findings and their relevance to future understanding of disease
processes, diagnosis or treatment? Has an adequate literature review pertinent to
the case been included?
Yes, the case is discussed fully in the context of the literature
OVERALL MANUSCRIPT POTENTIAL - Could an appropriately REVISED
version of this work represent a technically sound contribution?
Yes, this case report is suitable for publication
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: The current case describes the successful treatment
of a very rare tumor, intra-abdominal desmoplastic small round cell tumor
(IADSRCT). They describe the case with radiology, pathology and follow up
radiological response. The patient responded well to anlotinib, a new generation
multi-kinase inhibitor. There will be no phase studies for these rare type tumors,
therefore the evidence produced from case reports are extremely important.
REQUESTED REVISIONS: 
Very well written, and produces evidence for this rare type of soft tissue
sarcoma.
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