Review for 10.1186/s12876-022-02220-1 (2022)

Reviewer’s report
Title: 
The role of faecal calprotectin in diagnosis and staging of colorectal
neoplasia: A systematic review and meta-analysis
Version: 
0 
Date: 
20 Nov 2021
Reviewer: 
Arnaud - Alvès
Reviewer's report:
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thank you for giving me the opportunity to review this article. in view of the
studies included and their heterogeneity, it seems appropriate to me to rewrite
the paper in the form of a literature review. indeed, the term meta-analysis seems
inappropriate to me because of the low inclusion of studies linked to the
different main objectives. the authors cannot draw any firm conclusions about
the impact of faecal calprotectin on the detection of adenomas and colorectal
cancer, nor can they draw any firm conclusions about the histological severity
criteria.reasons why a review of the literature rather than an attempt at a meta-
analysis seems more appropriate.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
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