Review for 10.1186/s12876-016-0503-7 (2016)

Reviewer ’s report  
Title : Associations between polymorphisms in folate -metabolizing genes and pancreatic c ancer 
risk in Japanese subjects  
 
Version:  0 Date:  24 Feb 2016  
 
Reviewer:  Arjun Gupta  
 
Reviewer's report:  
This is a well conducted case -control study reporting the association, or rather lack of it, between 
polymorphisms in folate -metabolizing genes and pancreatic cancer. I congratulate the authors for 
this work.  
I do  not have any major comments or suggestions for the authors. I would recommend 
acceptance of this article.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the n ecessary controls?  
If not, please specify which controls are required in your comments to the authors.  
Yes 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any s tatistics in the manuscript or would you recommend an 
additional statistical review?  
 
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
I am able to assess the statisti cs 
Quality of written English  
Please indicate the quality of language in the manuscript:  
Acceptable  
Declaration of competing interests  
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1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
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below. If your reply is yes to any, please give details below.  
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