Review for 10.1186/s12876-020-01574-8 (2020)

Reviewer’s report
Title: 
A polymeric diet rich in transforming growth factor beta 2 does not reduce
inflammation in chronic 2,4,6-trinitrobenzene sulfonic acid colitis in pre-pubertal
rats
Version: 
0 
Date: 
19 Nov 2020
Reviewer: 
Aysegül Aksan
Reviewer's report:
Reviewer's report
Title: A polymeric diet rich in transforming growth factor beta 2 does not reduce
inflammation in chronic 2,4,6-trinitrobenzene sulfonic acid colitis in pre-pubertal
rats
MS Number and Version: BMGE-D-20-01173, 1
Date: 19.11.2020
Reviewer's report:
I thank authors for their patience and thevery nice work, I personally enjoyed
reading the mnauscript. The content of the subject, A polymeric diet rich in
transforming growth factor beta 2 in colitis is promising, exciting and has a great
value of interest. Additionally, this is a clear and professionally written
manuscript and I have only a few minor recommendations to improve the
manuscript:
* Table 1: It is not clear to me which statistical test is used for the analysis and
what does p value reflects for each content. It would be useful to have an
explanation under the table and add the statistical tests used and the result that p
values reflect.
* I would also recommend authors to discuss the limitations and strength of their
study. I do know that they already did mention the limitations quite clear during
discussion, however it is always better to have it clearly as a summary before
conclusion again.
* If possible, figures need more resolution, they seem blurred. 
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes