Review for 10.1186/s12876-020-01308-w (2020)

Reviewer ’s report  
 
Title: Elevated Hemoglobin A1c is Associated with the Presence of Pancreatic Cysts in a High -
Risk Pancreatic Surveillance Program  
 
Version: 3 Date: 29 Feb 2020  
 
Reviewer: Kuan -Chih Chen  
 
Reviewer's report:  
 
Q1. Would you please add an additional table to show the type and proportion of the cysts found 
on first imaging in HRIs group?  
 
Q2. Since the majority of cysts  found in HRIs were branch duct type IPMN, how do you explain 
the finding because its malignancy risk is relatively lower than main duct type IPMN?  
 
Q3. Is there any basic science study to support the main finding of elevated HbA1c associated 
with pancreat ic cyst?  
 
Q4. Finally, based on your findings, do you have any suggestion for those HRIs with pancreatic 
cysts, such as early intervention?   
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Accep table  
 
Declaration of competing interests  
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4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
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below.  If your reply is yes to any, please give details below.  
 
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