Review for 10.1186/s12876-019-1014-0 (2019)

Reviewer ’s report  
 
Title: Influence of HLA on clinical and analytical features of pediatric celiac disease  
 
Version: 0 Date: 10 Apr 2019  
 
Reviewer: Inaki Irastorza  
 
Reviewer's report:  
 
I would recommend changing some p values from p< 10exp3/ p<10 -3  to p<0.001  
128: "Severity of mucosal lesion was also associated with sex, with males showing milder 
(Marsh 0 to  Marsh 3a)": It should be explained how and why patients with Marsh 0/1 have been 
diagnosed with CD.  
 
Are the methods appropriate and well described?  
If not, please specify wh at is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects requ ire further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declarat ion of competing interests, considering the following questions:  
 
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organisation that may in any way gain or lose financially from the publication of this  
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financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any pat ents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing  interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests'  
 
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