Review for 10.1186/s12876-017-0688-4 (2017)

Reviewer ’s report  
Title: Attenuating the Rate of Total Body Fat Accumulation and Alleviating Liver Damage by  
Oral Administration of Vitamin D -enriched Edible Mushrooms in a Diet -induced Obesity 
Murine  Model is mediated by an Anti -inflammatory Paradigm Shift  
 
Version: 2 Date: 27 Jun 2017  
 
Reviewer: Chang Seok Bang  
 
Reviewer's report:  
I found significant statistical problem in your data. Authors corrected statistical method 
according to my suggestion. After performing Kruskal -Wallis test, the post -hoc analysis is 
Mann -Whitney test. Authors did this test. However, the significant p -value in the post -hoc 
analysis cannot be <0.05. If 4 arms a re in the test, the post -hoc analysis is 6 times. Therefore, the 
p-value in the post -hoc analysis should be 0.05/6 by Bonferroni's correction. Another method is 
Tuckey's correction or pariwise comparison. Statistical review is still needed.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
Yes 
Are the conclusions drawn adequa tely supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommende d, please specify what aspects require further  
assessment in your comments  to the editors.  
I am able to assess the statistics  
Quality of written English  
Please indicate the quality of language in the manuscript:  
Acceptable  
Declaration of competing interest s 
Please complete a declaration of competing interests, considering the following questions:  
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the pub lication of this  
manuscript, either now or in the future?  
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
3. Do you hold or are you cu rrently applying for any patents relating to the content of the  
manuscript?  
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
5. Do you have any other financial competing interests?  
6. Do you have any non -financial competing interests in relation to this paper?  
If you can answ er no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
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on my report to the authors and, if the manuscript is accepted for publication, my named report 
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to the editors, whi ch will not be published.  
 
I agree to the open peer review policy of the journal