Review for 10.1186/s12876-022-02477-6 (2022)

Reviewer’s report
Title: 
Are we forgetting to carry out serum protein electrophoresis as part of
diagnosis workup? A case report
Version: 
0 
Date: 
04 Jun 2022
Reviewer's report:
The authors underline the importance to timely perform a serum protein
electrophoresis in a case of CVID.
This case report is well described.
On the other hand a serum protein electrophoresis should be a worldwide routine
test during a normal hospital recovery (not in Brazil?). In this case the patients
had multiple previous hospital receptions.
It is difficult to think that this serum exam had never been done during the
previous hospital accesses unless it was missed or underestimated.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
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Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
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