Review for 10.1186/s12876-020-01299-8 (2020)

Reviewer’s report
Title: ADAR expression and copy number variation in patients with advanced gastric cancer
Version: 0 Date: 04 Mar 2020
Reviewer: Jianzhong Zhang
Reviewer's report:
The  results  of  this  study  demonstrates  that  ADAR  mRNA  is  overexpressed  in  GC.  ADAR
overexpression  and  amplification  correlate  with  the  main  negative  clinic  pathological  factors.
Furthermore, increased ADAR expression was clearly correlated with poorer survival outcomes. But
the primers used for performing real-time PCR were just for ADAR1(not for all ADARs). The author
should give supplementary explanation.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
No
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional
statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further
assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
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