Review for 10.1186/s12876-020-01355-3 (2020)

Reviewer’ s report
Title: Transarterial Chemoembolization Combined with Iodine 125 Seeds Versus Transarterial
Chemoembolization Combined with Radiofrequency Ablation in the Treatment of Early andIntermediate Hepatocellular Carcinoma
Version: 1Date: 21 May 2020
Reviewer: Alessandro Vitale
Reviewer's report:
The authors well answered to my questions but they did not change the paper accordingly.In
particular they now calculated the IPTW but in the paper they continued to use PSM. If the authorscalculated IPTW, then they have to substitute all previous calculations and speculations regardingPSM with new calculations and speculations using IPT: tables 1, 4, 5 should be reformulated usingIPTW instead of PSM; similarly KM figures should be done using IPTW instead of PSM.In therevised paper I don't see figures 3 and 4.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
YesDoes the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
NoAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statisticsQuality of written English
Please indicate the quality of language in the manuscript:
Acceptable
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