Review for 10.1186/s12876-023-02951-9 (2023)

Title: Relation between triglycerides and the severity of acute pancreatitis combined with
nonalcoholic fatty liver disease: a retrospective study
Version: 1 Date: 05 Aug 2023
Reviewer's report:
PEER REVIEWER ASSESSMENTS:
OBJECTIVE - Full research articles: is there a clear objective that addresses a testable research
question(s) (brief or other article types: is there a clear objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols) appropriate for
the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor to allow
confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results reasonable and not
overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work technically
sound? If not, can revisions be made to make the work technically sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS:
GENERAL COMMENTS: Effect of triglycerides on the severity of acute pancreatitis combined
with nonalcoholic fatty liver disease: a retrospective study.
-The objective of the study was clear , study design was valid and scientifically precise
-author collected the data and divided into groups. Aldo perform diagnosis of NAFLD and TG
data, local complication were recorded and define organ failure.
- Logistic regression analysis of APFC in patients with AP combined with NAFLD were
performed that important for the aim and conclusion
-However the title needs to be changed
1-Triglyceride did not administered in the experiment, so it was not factor that affect the study,
whoever TG was markers measured in NAFLD so use the relation is better than effect and match
with the conclusion.
Title should be changed into: relation between triglycerides and the severity of acute pancreatitis
combined with nonalcoholic fatty liver disease: a retrospective study
2-Recomindation about the relation of TG and AP should be reported
3-Other measurements and marker may important for NAFLD confirmation as ultrasound
pictures, histopathology, ALT.AST.
ADDITIONAL REQUESTS/SUGGESTIONS:
Effect of triglycerides on the severity of acute pancreatitis combined with nonalcoholic fatty
liver disease: a retrospective study.
-The objective of the study was clear , study design was valid and scientifically precise
-author collected the data and divided into groups. Aldo perform diagnosis of NAFLD and TG
data, local complication were recorded and define organ failure.
- Logistic regression analysis of APFC in patients with AP combined with NAFLD were
performed that important for the aim and conclusion
-However the title needs to be changed
1-Triglyceride did not administered in the experiment, so it was not factor that affect the study,
whoever TG was markers measured in NAFLD so use the relation is better than effect and match
with the conclusion.
Title should be changed into: relation between triglycerides and the severity of acute pancreatitis
combined with nonalcoholic fatty liver disease: a retrospective study
2-Recomindation about the relation of TG and AP should be reported
3-Other measurements and marker may important for NAFLD confirmation as ultrasound
pictures, histopathology, ALT.AST.