Review for 10.1186/s12876-021-02034-7 (2022)

Reviewer’s report
Title: 
Effect of Helicobacter pylori infection on malignancy of undifferentiated-
type gastric cancer
Version: 
0 
Date: 
04 Sep 2021
Reviewer's report:
1) General comments
Dr. Tanaka, et al. analyzed 'Effect of Helicobacter pylori infection on malignancy
of undifferentiated-type gastric cancer'. This article is well presented. The
reviewer has some comments.
1. In Patients and methods in page 4 line 24 to 26, the authors classified 3 groups
such as UD-E, UD-I and UD-U. The reviewer would like to recommend to
perform statistical analysis using multiple comparison tests. 
2. In Results, in page 9 line from 5 to 13, the authors describe Figure 2 and
'Relationship of time since eradication with tumor diameter, color tone, and
depth of invasion in the UD-E group'. It is not easy to understand these results,
Figure 2 seems to be included many important results. Please explain these
results and Figure 2 carefully in Results and Figure legends. 
3. In Discussion, in page 9 line from 17 to 18, the authors describe 'We found
that
33.8% of all lesions in the group without HP infection……', please explain the
meaning of 33.8. The authors should show the 33.8 % in Results.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
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from apparent manipulation?
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