Review for 10.1186/s12876-021-01694-9 (2021)

Reviewer’s report
Title: 
Endoscopic resections for superficial esophageal squamous cell epithelial
neoplasia: Focus on histological discrepancies between biopsy and resected
specimens
Version: 
1 
Date: 
11 Dec 2020
Reviewer's report:
BMGE-D-20-01222
The authors have carried out comparative study between the histological
diagnoses made in small endoscopic biopsies and resected specimens. The study
concept is genuine and applicable for routine diagnostic purpose. However, there
are quite a few issues that require attention before the manuscript may be
considered for publication. Kindly pay attention to the following points -
1. Overall editing of the manuscript is required. There are a few scattered
sentences which are not meaningful as the sentences appear to be incomplete e.g.
in page no.5 line 16 after the reference 13, the sentences is incomplete. 
2. Kindly give the full form for IPCR/IPCL first before using the abbreviations
in the manuscript. 
3. Page 8, lines 17 and 18 - clarify the sentence "discrepancy to be related to
histological category of biopsy".
4. Page 9, first line, kindly explained the "non-intra-epithelial neoplasia".
5. Page 9, line 6, kindly used the full form for "MBM".
6. Page 12, line, kindly use the word small biopsy fragments rather than using
minor biopsy fragments. 
7. Overall editing of the manuscript is required. 
8. Table 2 : kindly check the errors in the sequences of the sentences. 
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes