Review for 10.1186/s12876-020-1165-z (2020)

Reviewer ’s report  
 
Title: Proportion of NAFLD patients with normal ALT val ue in overall NAFLD patients: a 
systematic review and meta -analysis  
 
Version: 0 Date: 10 Dec 2019  
 
Reviewer: Maissa Elraziky  
 
Reviewer's report:  
 
Important research question  
 
Excellent Methodology description  
 
More detailed  description of the characteristics of patients with normal ALT levels among 
NASH patients is highly required ( demographic features, BMI, Metabolic syndrome, 
histopathology if ever available,.....) as this the real challenging diagnostic dilemma in non -
biopsy proven NASH population.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any sta tistics in the manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistic s 
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
Declaration of competing interests  
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5.  Do you have any other financial competing interests?  
 
6.  Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please g ive details below.  
 
I declare that I have no competing interests  
 
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