Review for 10.1186/s12876-020-01248-5 (2020)

Reviewer ’s report  
 
Title: 25(OH) D3 alleviate liver NK cytotoxicity in acute but not in chronic fibrosis model of  
BALB/c mice due to modulations in vitamin D receptor  
 
Version: 0 Date: 20 Sep 2019  
 
Reviewer: Maissa Elraziky  
 
Reviewer's report:  
 
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The aim of The work is not clearly stated as well as the plan of work.  
The authors used ALT and SMA as markers of fibrosis while they are markers of hepatocyte 
injury.  
Sample size was not cal culated or included.  
The interpretation of results is overestimated rushing to conclusions not solidified by the results 
obtained ,creating false cause/effect relationship.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in t he manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
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