Review for 10.1186/s12876-021-01730-8 (2021)

Reviewer’s report
Title: 
Gastrointestinal symptoms as first remarkable signs of ANCA-associated
granulomatosis with polyangiitis: case report and review
Version: 
0 
Date: 
08 Sep 2020
Reviewer's report:
The paper concerns the GI involvement in GPA vasculitis. 
Case presentation
The exact timing of events is not clear. 
Was the creatinine elevation found in 
the
nephrology department or in the emergency room? 
Line 81 please insert the value of calprotectin
Line 93 Please insert the dosage of Methylprednisolone and Cyclophosphamide
Line 103 for the diagnosis of GPA vasculitis, the finding of granuloma in renal
biopsy is not necessary
Discussion 
It is too long and confuse. 
The authors describe the case where Gi involvement
was the first and ONLY sign of GPA but 
I am not sure that GI involvement was
the first symptoms of GPA, because he has 
microhaematuria 
and had had
recurrent sinusitis. GI involvement was only one of the sign of the vasculitis. 
Are they sure that duodenal 
bleeding was due to vasculitis? Please specify why.
Line 225-228 interrogative sentences should not be inserted into the text 
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