Review for 10.1186/s12876-020-01471-0 (2020)

Reviewer’ s report
Title: Peritumoral ductular reaction can be a prognostic factor for intrahepatic cholangiocellular
carcinoma
Version: 2Date: 24 Jul 2020
Reviewer's report:
1. In my previous comment ' The clinicopathological parameters in table 1 should include the
pathological stage', the pathological stage meant the AJCC TNM stage such as II or III, not thehistological grade or differentiation.2. Before multivariate survival analysis, whether any other clinicopathological features such aspathological stage or metastasis, besides DR grade, had significant impact on the prognosis shouldbe described.
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NoDeclaration of competing interests
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(default)
Is the study design appropriate to answer the research question (including the use of appropriate
controls), and are the conclusions supported by the evidence presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?YesIs the use of statistics and treatment of uncertainties appropriate?YesIs the presentation of the work clear?YesAre the images in this manuscript (including electrophoretic gels and blots) free from apparent
manipulation?
Yes