Review for 10.1186/s12876-020-01438-1 (2020)

Reviewer’ s report
Title: Clinical characteristics of adult T-cell leukemia/lymphoma infiltration in the gastrointestinal
tract
Version: 4Date: 31 Jul 2020
Reviewer's report:
Comments to the Author:
It seems that the authors responded properly to the comments of the reviewer #1. I have several
minor comments.
1. Concluding remarks are too strong compared to the level of evidence found in this study. Please
consider to change the sentences in the conclusions in the Abstract and Manuscript.Abstract & Manuscript: "Physicians should perform GI endoscopy for ATLL patients without skinlesions."-> "GI endoscopy may be considered for ATLL patients without skin lesions."Manuscript: "Physicians should perform GI endoscopy to actively investigate ATLL infiltration inthe GI tract and evaluate the endoscopic findings characteristic of lymphoproliferative disease."-> Physicians may perform GI endoscopy …"
2. It was difficult to understand how categorical variables were presented in the Table 1 and 4.
Please revise the tables as the following example:Gender, n/n (male/female) 23/17-> Gender, n (%)
Male 23 (57.5%)
Female 17 (42.5%)In addition, please conduct statistical comparison between infiltration and non-infiltration groupsand provide p-value in the Table 4.
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(default)
Is the study design appropriate to answer the research question (including the use of appropriate
controls), and are the conclusions supported by the evidence presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
YesIs the use of statistics and treatment of uncertainties appropriate?YesIs the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free from apparent
manipulation?
Yes