Review for 10.1186/s12876-018-0770-6 (2018)

Reviewer ’s report  
 
Title: 3D high -resolution anorectal manometry i n patients wit h perianal fistulas: comparison 
with 3D-anal ultrasound  
 
Version: 0 Date: 22 Feb 2018  
 
Reviewer: Giuseppe Chiarioni  
 
Reviewer's report:  
 
I read with interest this well developed retrospective study on potential future application of 
HR_ARM. The Authors should be commended for providing succh innovative data. However, 
the actual findings need to be supported by including a population of controls without fistulizing 
disease. No additional suggestions on this side.  
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is requir ed in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please e xplain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following qu estions:  
 
1. Have you in the past five years received reimbursements, f ees, funding, or salary from an 
organisation that may in any way gain or lose financial ly from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation t hat may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents  relating to  the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing i nterests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare tha t I have no competing interests  
 
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on my report to the authors and, if the manuscript is accepted f or publication, my named report 
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