Review for 10.1186/s12876-020-01572-w (2021)

Reviewer’s report
Title: 
Total cholesterol concentration predicts the effect of plasmapheresis on
hypertriglyceridemic acute pancreatitis: a retrospective case-control study
Version: 
0 
Date: 
04 Sep 2020
Reviewer's report:
This article is about to investigate whether the total cholesterol concentration
predicts the effect of plasmapheresis on
hypertriglyceridemic acute pancreatitis. The article is well written. The methods
is retrospective, but its limitation is highlighted in the discussion. 
I have minor points:
INTRODUCTION: 
1) The reference list is a little bit old. Please cite more recent cohorts as well
(PMID: 31620021, PMID: 32402696). Page 4, line 4-12
METHODS
2) Is this inclusion criteria match the IAP/APA guideline? If yes please cite it.
(PMID: 24054878) Page 5, line 34
DISCUSSION
3) It should be stated that we still do not know that plasmapheresis is beneficial
in AP. RCTs should be performed. One RCT has just started (PMID: 31959416)
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
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from apparent manipulation?
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