Review for 10.1186/s12876-018-0784-0 (2018)

Reviewer ’s report  
 
Title:  Celiac Crisis, a rare and profound presentation of Celiac disease: a case report.  
 
Version: 0 Date: 31 Dec 2017 
 
Reviewer:  Naire  Sansotta  
 
Reviewer’s report:  
 
Congratulations to the authors, they have done a  very good job of describing this interesting 
case.  
 
 
I have just few questions:  
 
- what about AST and ALT (transaminases) in your woman?  
 
- did you ckeck her celiac serology (TTgIgA, total IgA and EMA) at the time of intestinal 
biopsy?As you know, intestinal villous atrophy is not exclusive for celiac disease  
 
- did you determine her HLA?  
 
- why did she develop pulmonary embolism? I guess it was not related with celiac disease.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Unable to assess  
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is rec ommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
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