Review for 10.1186/s12876-022-02179-z (2022)

Reviewer’s report
Title: 
Isolated IgG4-related cholecystitis with localized gallbladder wall
thickening mimicking gallbladder cancer: a case report and literature review
Version: 
0 
Date: 
11 Nov 2021
Reviewer: 
Tomoyuki Abe
Reviewer's report:
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Thank you for the invitation to review this manuscript. It is well-written and an
original work focusing on the diagnosis and rarity of isolated IgG4-related
cholecystitis with localized gallbladder wall thickening mimicking gallbladder
cancer. It is very rare and difficult to make a precise diagnosis of this disease.
Considering the low rate of serum IgG4 positivity, dynamic CT and EUS would
play an important role in diagnosis. As Authors described in Figure 3 that a
smooth layered thickening is reflected by the histological layered lymphocytic
infiltration in the gallbladder wall. This finding is enormously important to
distinguish gallbladder carcinoma and this disease. I agree with Author's
opinion. This manuscript is worth for the publication in its form.
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