Review for 10.1186/s12876-021-01950-y (2021)

Reviewer’s report
Title: 
Long term survival of a patient with microsatellite stable refractory
colorectal cancer with regorafenib and PD-1 inhibitor sintilimab – A Case
Report and Review of Literature
Version: 
0 
Date: 
18 Jul 2021
Reviewer's report:
A great case report by Zhang and colleagues regarding the chemotherapeutic
response of colorectal adenocarcinoma with regorafenib and PD-1 inhibitor
sintilimab.
I recommend a minor revision before final acceptance for publication.
- I recommend a detailed English revision by a native speaker.
- Minor changes like, page 6, line 124, not pathohistological result, it is
histopathological result.
- In the same page, please mention the TTNM Stage of Cancer. 
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Is the study design appropriate to answer the research question (including the use
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presented?
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