Review for 10.1186/s12876-018-0883-y (2018)

Reviewer ’s report  
 
Title: Helicobacter pylori Infection Progresses Proximally Associ ated with Pyloric Metaplasia in 
Age-dependent Tendency: A Cross -Sectional Study  
 
Version: 0 Date: 26 Aug 2018  
 
Reviewer: Akwi Asombang  
 
Reviewer's report:  
 
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Overall, this is interesting work. I have a few comments/edits/recommendations:  
 
1. Some grammatical errors/spelling for uniformity ie proximate versus proximal (consider using 
proximal); mid -aged versus middle -aged  (consider using middle aged)  
 
-In the background section: "Evidence has" instead of "evidences have"  
 
-Background: line 10  change to " which are referred to" instead of which were called  
 
-Background: Line 13 - the authour should be Graham not Grahm  
 
-Page 4 line 17: change from "The present study"...to "Our study"  
 
 
2. Exclusion criteria: why was category 4 excluded?  
 
 
3. Page 5, line 9: change from "All patients" to "Patients"  
 
 
4. Page 5, line 11: Change from "information consent" to "informed consent"  
 
 
5. Page 6: Histology/HP status: Line 13 on -wards: what is defined as "Small amount" "moderate" 
"mild" "very mild" etc  
 
 
6. What happened to patients between 50 and 60 yrs  
7. Statistical analysis: Explain when the different techniques were specifically utilized instead of 
saying " ...were used as and when required"  
 
 
8. Page 8 line 4: change from "distribution runs to proximal s tomach"...to "distribution in the 
proximal..."  
 
 
9. Page 12 line 7 does not make sense: " At the meanwhile..." -please clarify  
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please spe cify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or w ould you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I recommend additional statistical review  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
 
 
 
 
 
 
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