Review for 10.1186/s12876-020-01477-8 (2020)

Reviewer’ s report
Title: The Clinical Efficacy and Adverse Effects of Entecavir plus Thymosin alpha-1 Combination
Therapy versus Entecavir Monotherapy in HBV-related Cirrhosis: A Systematic Review andMeta-analysis
Version: 1Date: 14 Sep 2020
Reviewer: Marcello Persico
Reviewer's report:
This paper sounds more solid and ameliorates after revision suggested by three reviewers and my
be accepted for publication.
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Reviewer Publication Consent. I agree for my report to be made available under an Open Access
Creative Commons CC-BY License (http://creativecommons.org/licenses/by/4.0) if this manu-script is accepted for publication. Any comments that I do not wish to be included in the publishedreport have been included as confidential comments to the editor, which will not be published.Ifyou are not happy for us to publish this report, please contact the editorial office before completingthe review.If you wish, you can include your name in your published report. Please note you mustdecide whether to include your name at the start of the process and confirm this decision wheneverprompted. If you change your decision later, we will not be able to publish your name.
I agree to the terms of the CC-BY 4.0 license; please publish my name with my report.Is the study design appropriate to answer the research question (including the use of appropriate
controls), and are the conclusions supported by the evidence presented?
YesAre the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?YesIs the presentation of the work clear?YesAre the images in this manuscript (including electrophoretic gels and blots) free from apparent
manipulation?
Yes