Review for 10.1186/s12876-015-0397-9 (2015)

Reviewer ’s report  
 
Title: Clinical features and STK11 gene mutations in Chinese children with Peutz -Jeghers  
syndrome  
 
Version: 0 Date: 15 Sep 2015  
 
Reviewer: Thomas McGarrity  
 
Reviewer ’s report:  
 
In the Abstarct and results s ection state that their were 1 3 cases of PJS, of which 12 had gene 
testing and 11 showed a mutation.  
 
Add reference ,page 4 sentence 20  
 
Page 5, line 23 substitute 'survey' for surveil.  
 
Page 6, lines 26 - 34, provinces are in " eastern' China;southwest Chin a,northwestChina  
 
It's unclear if case 11 or 13 did not receive gene testing for example as stated on page 7; bottom 
of page 8.  
 
Page 8, sentences 29 through 44, this is part of Discussion and not part of Results section.  
 
Page 11, second paragraph, sentence   29 ' presentation of the macula' and sentence line 
38,'Polyps in the gastro... don't make sense.Line 33 substitute ' initial clinical presentation' for 
initial syndrome.Also paragraph 2 , page 11 could be combined with information on page 10  
 
Are the methods appropriate and well described?  
If not, please specify what is requi red in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
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