Review for 10.1186/s12876-020-01324-w (2020)

Reviewer’ s report
Title: Nomogram based on blood lipoprotein for estimation of mortality in patients with hepatitis
B virus-related acute-on-chronic liver failure
Version: 0Date: 30 Nov 2019
Reviewer: L. Lesmana
Reviewer's report:
Dear author,This is an interesting novel study, however, there are some major concerns:1. It is not
clear why hepatitis B patients was chosen in the setting of Acute on Chronic Liver Failure. Pleaseexplain more about this. Yet, in the introduction the background is only about ACLF.2. The authorshould include the recent AARC scoring system and explain why nomogram is still need to bedeveloped instead this new scoring system (developed by Asian Pacific Association of The Studyof The Liver).3. The biochemistry test parameter need to be defined clearly at the beginning suchas TC, TG, etc.4. The manufacture should be written the name and production country.5. Whyauthors choose 3-months mortality?
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
YesDoes the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statisticsQuality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
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