Review for 10.1186/s12876-021-01611-0 (2021)

Reviewer’s report
Title: 
Efficacy of a novel hemostatic adhesive powder in patients with upper gastrointestinal tumor
bleeding
Version: 
1 
Date: 
03 Jan 2021
Reviewer's report:
Congratulation to the author's work. I think this is a good preliminary study for a promising material in
endoscopic hemostasis. The concerns from previous review has been well-addressed and the article has
been revised accordingly. However, my only suggestion is to make the conclusion softer. As both
reviewers pointed out, the major limitation of this study is a lack of comparison group. 
Hence, I would revise the conclusion like: "This single-arm study demonstrated UI-EWD was associated
with excellent immediate hemostasis rate and safety profile as well as low rebleeding for upper GI tumor
bleeding. Further studies are necessary to confirm its efficacy compared to conventional endoscopic
modality." I look forward to seeing further results and the use of this novel treatment in more patients.
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Is the study design appropriate to answer the research question (including the use of appropriate controls),
and are the conclusions supported by the evidence presented?
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