Review for 10.1186/s12876-018-0928-2 (2019)

Reviewer ’s report  
 
Title:  Risk Factors and Long -term Outcome of Disease Extent Progression in Asian Patients 
with Ulcerative Colitis: A Retrospective Cohort Study  
 
Version: 1 Date: 02 Oct 2018 
 
Reviewer:  Vineet  Ahuja  
 
Reviewer’s report:  
 
1.The authors have not commented upon one facet of progres sive disease:  
 
How many patients had caecal/periappendiceal patch and was that factor related to progression 
of the disease ?  
 
 
2. Only 59% of patients were on oral or topical 5ASA's. As 5ASA's are the cornerstone of 
therapy in UC , what were the possible r easons that only 60% of patients were taking 5ASA's.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, plea se specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
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financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, fund ing, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
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below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
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