Review for 10.1186/s12876-020-01386-w (2020)

Reviewer’ s report
Title: Changes in Inflammatory Cytokines, Antioxidants and Liver Stiffness after Chelation
Therapy in Individuals with Chronic Lead Poisoning
Version: 0Date: 03 Jan 2020
Reviewer's report:
It's an interesting study. But there is no message for prophylaxis from the cause.Why is the lead
level not controlled before starting the study?After chelation therapy, in any other disease, for example, "Wilson's disease" do inflammatoryfactors also change? So what does this have to do with lead contamination?Due to the large drop in sample size, there is a need for statistical judgment.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
NoDoes the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
YesAre the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
NoAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I recommend additional statistical reviewQuality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being publishedDeclaration of competing interests
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