Review for 10.1186/s12876-021-01749-x (2021)

Reviewer’s report
Title: 
Successful Treatment of Infantile Oxysterol 7
α
-hydroxylase Deficiency
with Oral Chenodeoxycholic Acid
Version: 
1 
Date: 
16 Feb 2021
Reviewer's report:
The authors have made a satisfactory response to all the points I raised, in
particular confirming the identity of urinary metabolites by tandem mass
spectrometry (MS/MS) and liquid chromatography electrospray ionisation
tandem spectrometry LC-ESI MS/MS).
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes