Review for 10.1186/s12876-020-1158-y (2020)

Reviewer’ s report
Title: Aspirin Decreases Hepatocellular Carcinoma Risk in Hepatitis C Virus Carriers: A
Nationwide Cohort Study
Version: 2Date: 28 Dec 2019
Reviewer: Theodoros Androutsakos
Reviewer's report:
I think that your work is now much better presented. The only comment I would like to make is
that I think that in your abstract at the conclusion section you probably mean something differentthat what you are saying. Your results do not indicate that the protective effect of aspirin occurthrough inhibition of cyclooxygenase enzyme pathway. What you are showing is that aspirin has aprotective effect, if that comes through inhibition of that pathway or not is not proven in yourstudy. Other than that your study is, in my opinion, ready to be published.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
YesDoes the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I am able to assess the statisticsQuality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
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