Review for 10.1186/s12876-021-01640-9 (2021)

Reviewer’s report
Title: 
Pre-inhalation of hydrogen-rich gases protect against caerulein-induced
mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression
Version: 
1 
Date: 
15 Sep 2020
Reviewer's report:
The interesting study investigates the role of 
Hsp60 protein on the pancreatic
pathological changes, plasma amylase and lipase activity, and the increase of
plasma IL-1 and IL-6 levels in acute pancreatitis mice were significantly
improved by the hydrogen-rich gases pretreatment. The novelty of this study
could be of help in the understanding of the mechanism of acute pancreatitis.
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Is the study design appropriate to answer the research question (including the use
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