Review for 10.1186/s12876-020-01545-z (2020)

Reviewer’s report
Title: 
Investigation of the clinical significance and pathological features of
lanthanum deposition in the gastric mucosa
Version: 
0 
Date: 
31 Aug 2020
Reviewer's report:
I think it is very interesting study that the white appearance of lanthanum
deposition depends on the amount of infiltrating histiocytes. It is necessary to
clarify more derails before accepting the paper.
(1) The degree of mucosal atrophy and La deposition are compared in Table 1,
the value of La deposition groups seems to be wrong. Please correct.
(2) Table 2 shows that the dialysis period is long in the LaC taking group. Why?
(3) The occupancy rate of the histiocytes in the lamina propria is described.
Please describe in detail how the occupancy rate was measured.
(4) In table 3, please describe how you define the small and large 
amounts of La
deposition.
(5) The degree of infiltration of histiocytes is mild and strong. How do you
define them? I think severe is the right word, not strong.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes