Review for 10.1186/s12876-020-01542-2 (2020)

Reviewer’s report
Title: 
Evidence-Based Medicine and Management of Hepatocellular Carcinoma
in Thalassemia.
Version: 
0 
Date: 
29 Jul 2020
Reviewer: 
John Koskinas
Reviewer's report:
This is, as I understand, an editorial to a paper published in the same journal
regarding management of HCC in patients with thalassemia
The grey areas discussed by the author are really correct and reflect the lack of
solid data in many areas of HCC in this group of patients 
Some of thee areas include: 1) the screening programs for HCC in all patients
with thalassemia and 2) transplantation should not be considered a
contraindication for thalassemic patients any more. (I personally agree for both
issues) 
I would encourage the author to comment on the importance of screening for
HCC all patients with thalassemia with respect to risk factors; chronic iron
accumulation alone or in combination with long standing hepatitis C even after
eradication with the new DAAs. 
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