Review for 10.1186/s12876-022-02240-x (2022)

Reviewer’s report
Title: 
A descriptive study of high resolution total colonic intracavitary
manometry and colonic transit test in the diagnostic efficacy of functional
constipation in Chinese patients
Version: 
2 
Date: 
14 Feb 2022
Reviewer's report:
Authors have compared the diagnostic ability of functional constipation between
HRCM and CTT. The topic seems to be relevant and the study would have some
impact on clinical practice. 
Comments:
1. Did authors use any statistical tests in comparing the diagnostic ability
between HRCM and CTT? If not, how did authors compare them?
2. There would be some bias such as selection bias in this study since patients
only who underwent surgery and who underwent both HRCM and CTT. Please
consider to add the description about limitations of this study. 
3. Methods, Patients, Please replace "July 20016" with "July 2016".
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
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Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes