Review for 10.1186/s12876-021-01707-7 (2021)

Reviewer’s report
Title: 
Gene Expression Profiling of Inflammatory Cytokines in Esophageal
Biopsies of Different Phenotypes of Gastroesophageal Reflux Disease: a cross-
sectional study
Version: 
0 
Date: 
01 May 2020
Reviewer: 
Peter W Dettmar
Reviewer's report:
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The study has been well designed and the data generated interesting and well
presented. 
There are a few minor comments which need addressing. These are as follows:
1. Page 5 line 99 - Define GWAS 
2. Page 11 line 241- remove 
the words in a 
3. Page 11 line 254 - should be show not showed
4. Page 13 line 294 - remove the word in should read "with EE compared"
5. Page 13 line 294 - add the word the should read "with the controls"
6. Page 13 line 304 - remove the word in should read "MMP-9 compared"
7.Page 13 line 304 - add the word the should read "with the control group"
8. Page 13 line 310 - add the word it should read "in this study it is important"
9. Page 14 line 315 - add the word in should read "increase in the expression"
10. Page 14 line 324 - first word should be personalized medicine 
11, Page 14 line 331 - should read reversing the alteration of these genes. 
The above are minor corrections which need correcting.
Are the methods appropriate and well described?
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Yes
Does the work include the necessary controls?
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authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
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Yes
Are you able to assess any statistics in the manuscript or would you
recommend an additional statistical review?
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require further assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
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Acceptable
Declaration of competing interests
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