Review for 10.1186/s12876-021-01843-0 (2021)

Reviewer’s report
Title: 
Integrated Analysis of the Functions and Prognostic Values of RNA
Binding Proteins in hepatocellular carcinoma
Version: 
0 
Date: 
06 Sep 2020
Reviewer's report:
The authors investigated that functions and prognostic values of RNA binding
proteins in HCC. As a result, the authors identified novel biomarkers in HCC.
I would recommend it for acceptance with several corrections.
Major
The point is result of immnohitochemistry in Figure 5B. A detailed analysis
should be done on the relationship between the final positive rate and the
prognosis.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
No
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
No