Review for 10.1186/s12876-020-01277-0 (2020)

Reviewer’ s report
Title: High incidence of hepatocellular carcinoma and cirrhotic complications in patients with
psychiatric illness: A territory-wide cohort study
Version: 1Date: 21 Mar 2020
Reviewer: Gar-Yang Chau
Reviewer's report:
Please include all comments for the authors in this box rather than uploading your report as an
attachment. Please only upload as attachments annotated versions of manuscripts, graphs,supporting materials or other aspects of your report which cannot be included in a textformat.Please overwrite this text when adding your comments to the authorThe manuscriptdescribes a study of the incidence of hepatocellular carcinoma (HCC) and cirrhotic complicationsin psychiatric patients in a large cohort of psychiatric patient in Hong Kong without evidence ofprior liver-related events. The findings support the results of other studies which have noted thatpsychiatric patients is associated with more advanced HCC, liver cirrhosis and decreased survival.Although these findings are not novel, they do have significance given the unique populationstudied.
Are the methods appropriate and well described?
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Yes
Does the work include the necessary controls?
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YesAre the conclusions drawn adequately supported by the data shown?
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YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
I recommend additional statistical reviewQuality of written English
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Acceptable
Declaration of competing interests
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