Review for 10.1186/s12876-018-0743-9 (2018)

Reviewer ’s report  
 
Title : Treatment of long -segment Barrett's adenocarcinoma by complete circular endoscopic 
submucosal dissection: a case report  
 
Version: 0 Date: 29 Jun 2017  
 
Reviewer: Diana Sacchi  
 
Reviewer's report:  
 
This case report is well -written in an engaging and lively style and deals with an interesting 
endoscopic topic which is the application of ESD as a conservative therapeutic option in case of 
LSBA. However, I would seize the chance to express two minor concerns:  
1- I strongly suggest you check the figure 3 -d: it may be better a higher magnification to show 
the minimal tumor extension under the adjacent squamous epithelium;  
2- I would appreciate if you could be more precise about the use of ESD as a therapeutic option 
for early esophageal adenocarcinoma. Actually, early adenocarcinoma (T1) is subdivided 
into intramucosal (T1a) and submucosal (T1b) lesions. Therefore, in your case report, ESD is 
suggested as a therapeutic option for just T1a early adenocarcinoma, isn't it?  
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Unable to assess  
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional sta tistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declara tion of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or los e financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the ma nuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare I have no competing interests.  
 
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