Review for 10.1186/s12876-020-01188-0 (2020)

Reviewer’s report
Title: Diagnostic efficacy of double-balloon enteroscopy in patients with suspected isolated small
bowel Crohn’s disease
Version: 1 Date: 28 Nov 2019
Reviewer: Steven Naymagon
Reviewer's report:
I applaud the authors for a very nice manuscript.  They provide a nice summary of the utility of DBE in
CD.  
The major question for me as reader is whether DBE provides any incremental benefit over more non-
invasive modalities for diagnosing CD.  Meaning, if I perform colonoscopy, EGD, VCE, and CTE on a
patient I can usually make the diagnosis of CD.  How often does DBE add value after the above listed
studies are performed completely and adequately?  I was not able to ascertain this from the manuscript.
Can this information be clearly included in the table and text?  
It seems that many of the patient included in the analysis did not have VCE or CTE.  Why not?  
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Unable to assess
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?
If an additional statistical review is recommended, please specify what aspects require further
assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
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