Review for 10.1186/s12876-017-0676-8 (2017)

Reviewer ’s report  
 
Title: Micro -costing analysis of guideline -based treatment by direct -acting agents: the real -life 
case of hepatitis C management in Brazil  
 
Version: 1 Date: 16 Jul 2017  
 
Reviewer: Antonio Ciaccio  
 
Reviewer's report:  
 
Abstract, by line 48: I would rather invert the sentence placing PPP results first and then regimen 
to fol low, in brackets.  
line 253: "when" has to be deleted.  
 
Table 1:  
line "2015B": in the column "drugs" SOF and SIM are reported, while in the column 
"interventions" only SOF and DCV are mentioned.  
Are the methods appropriate and well described?  
If not, please specify what is required in your comme nts to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please expl ain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assess ment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
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below.  If your reply is yes to any, please give details below.  
 
Research Grant from Gilead Sciences, Advisory board for Gilead and Abbvie. Speaking 
honoraria from Abbvie.  
 
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