Review for 10.1186/s12876-021-01826-1 (2021)

Reviewer’s report
Title: 
The burden and management of anemia in Greek patients with
inflammatory bowel disease:  a retrospective, multicenter, observational study
Version: 
0 
Date: 
25 Apr 2021
Reviewer's report:
I have following remarks:
1. English requires revision
2. Introduction is chaotic, general, and not fully related to the study. Data
regarding epidemiological rates for IBD in Greece are missing. Some data are
repeated. 
3. Were patients with accompanying celiac disease excluded from the study?
Were vegetarian in the studied group?
4. Authors mentioned two types of the surgeries (right hemicolectomy and
enterectomy; page 6, line 12). None of them is performed as a standard surgical
therapy in UC. Were in the studied group patients with short bowel syndrome
after "enterectomy" then? 
5. I my opinion other serious limitation of the study is the way to evaluate IBD
activity (clinical scores) as it is well known that the golden standard in IBD
activity assessment is endoscopy.
6. What about calprotectin? Was this biomarker applied in the IBD centers?
7. If the authors write about EIMs they should specify that they mean others
EIMs than anemia.
8. Why ferritin was available only for 60% of patients? Why almost every forth
patient did not receive therapy for anemia?
9. In my opinion it would be worth to make an attempt to classify anemia into
ACD, IDA, B12 deficiency etc. instead of episodic etc.
10. I would recommend that Authors highlight the novel aspects of the study.
11. I think that prospective study on anemia in the population of IBD patients
monitored and treated in IBD centers would have really special value.
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Is the study design appropriate to answer the research question (including the use
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