Review for 10.1186/s12876-021-01599-7 (2021)

Reviewer’s report
Title: 
Transjugular Intrahepatic Portosystemic Shunt for Hepatic Sinusoidal
Obstruction Syndrome Associated with Consumption of Gynura Segetum
Version: 
1 
Date: 
14 Oct 2020
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
OBJECTIVE - Full research articles: is there a clear objective that addresses a
testable research question(s) (brief or other article types: is there a clear
objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols)
appropriate for the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor
to allow confidence in the results?
N/A - no experiments or analyses
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results
reasonable and not overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work
technically sound? If not, can revisions be made to make the work technically
sound?
Yes - current version is technically sound
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: 
In this interesting retrospective study, the authors evaluate the efficacy and
safety of transjugular intrahepatic portosystemic shunt (TIPS) on hepatic
sinusoidal obstruction syndrome (HSOS) associated with consumption of
Gynura segetum.
The study is well structured and well conducted, with a satisfactory statistical
analysis, despite the reduced number of cases. 
More REFERENCES are needed.
TABLES are Ok.
LANGUAGE: 
Minor language polishing is needed.
IMAGES are Ok, but can be organized in composite.
REQUESTED REVISIONS: 
Nothing. It has already been revised.
ADDITIONAL REQUESTS/SUGGESTIONS: 
Minor language polishing and make a composite of the pictures.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes