Review for 10.1186/s12876-020-01550-2 (2020)

Reviewer’s report
Title: 
Mixed adenoneuroendocrine carcinoma of the hepatic bile duct:a case
report and review of the literature
Version: 
0 
Date: 
09 Feb 2020
Reviewer: 
Stefano Rausei
Reviewer's report:
The case presented by Zhong et al is rare and interesting. However, the
manuscript could be improved.
1) In different parts Authors show too many details, for example in "case
history" too many unhelpful laboratory exams as well as in "discussion" too
many weel-known classifications!
2) The reliability of CT scan is not so clear if compared with surgical report:
particularly, which surgical finding did Authors describe about suspected
invasion of portal hepatic hilum area and retroperitoneal nodes?
3) How Authors did perform follow-up of patient? CT? MR? Which f-up
schedule?
4) A picture of the specimen or the surgical field could improve the manuscript.
5) In the Discussion Authors should better clarify the link between "the early
onset" and "the poor prognosis" of this tumor.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the
authors.
Unable to assess
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you
recommend an additional statistical review?
If an additional statistical review is recommended, please specify what aspects
require further assessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
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questions:
1
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salary from an organisation that may in any way gain or lose financially
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paper?
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