Review for 10.1186/s12876-020-01446-1 (2020)

Reviewer’ s report
Title: Gastric submucosal abscess caused by Edwardsiella tarda infection: a case report
Version: 2Date: 25 Aug 2020
Reviewer's report:Thank you for your response to previous comments. The authors have clarified their hypothesis
that cholangitis by E tarda (in turn probably caused by obstructive gallstones) was the initial
problem that subsequently led to submucosal and intra-abdominal abscess formation, most likelyby means of direct spread. This succession of unlikely events remains striking and unfortunatelythe exact relationship of clinical findings will never be ascertained due to the lack of a bile culture.Although this is a limitation, this is now addressed by the authors in their discussion. All thingsconsidered, this report of a very rare case represents a valuable addition to literature.
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Is the study design appropriate to answer the research question (including the use of appropriate
controls), and are the conclusions supported by the evidence presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?YesIs the use of statistics and treatment of uncertainties appropriate?YesIs the presentation of the work clear?YesAre the images in this manuscript (including electrophoretic gels and blots) free from apparent
manipulation?
Yes