Review for 10.1186/s12876-018-0857-0 (2018)

Reviewer ’s report  
Title: Tolvaptan treatment improves survival of cirrhotic patients with ascites and hyponatremia  
 
Version: 1 Date: 08 Mar 2018  
 
Reviewer: Yoshihiko Yano  
 
Reviewer's report:  
1. Figure legends should be written more detailed.  
2. Figure 2B should be shown the comparison of cirrhotic patients with hyponatremia between 
Tolvaptan treated patients and control patients. Present 2B should be changed to 2C. It is a bit 
difficult to und erstand why Tolvaptan -resolved and -unresolved patients were divided? Were 
all of Tolvaptan treated cirrhotic patients with hyponatremia improved short term survival? If 
not, it should be modified the abstract and conclusion.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
Yes 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
Yes 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
Yes 
Are you able to assess any statistics in the manus cript or would you recommend an 
additional statistical review?  
If an addition al statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
I am able to assess the statistics  
Quality of written English  
Please indicate the quality of language in the manuscript:  
Not suitable for publication unless extensively edited  
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Nothing special  
 
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