Review for 10.1186/s12876-020-01588-2 (2021)

Reviewer’s report
Title: 
DSG2 expression is low in colon cancer and correlates with poor survival
Version: 
0 
Date: 
12 Sep 2020
Reviewer's report:
There have been some studies about clinical value of DSG2 in gastric cancer, so
the novelty of this study was not significant. 
Author stated that 'few studies have
investigated DSG2 expression and its function in CC', which is not accuate. And
in this study, author did not provide enough data to support the mechanism of
DSG2.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
No
Are the methods sufficiently described to allow the study to be repeated?
No
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Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes