Review for 10.1186/s12876-018-0793-z (2018)

Reviewer ’s report  
 
Title:  A subclinical high tricuspid regurgitation pressure gradient independent of the mean 
pulmonary artery pressure is a risk factor for the survival afte r living donor liver transplantation  
 
Version: 2 Date: 26 Feb 2018 
 
Reviewer:  Georg  Gyoeri  
 
Reviewer’s report:  
 
As for this revision, I do not have the feeling that the authors were able to adress the issues raised 
in the last draft.  
 
The retrospective small series data provided do not support the conclusion that a subclinical 
pulmonary hypertension has a negative effect on LDLT outcomes.  
 
Unfortunately HVPG measurements are not available, the treatment for varices does not function 
as a good substitute here.  
 
As mentioned before the majority of patients died from factors unrelated to pulmonary 
hypertension.  
 
All issues mentioned should be discussed and adequately addressed.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include t he necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to  assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs some language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in  the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisat ion that may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
no competing interests to declare  
 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my report to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
responses. I ag ree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
which I do not wish to be inc luded in my named report can be included as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal