Review for 10.1186/s12876-020-01375-z (2020)

Reviewer’ s report
Title: Endoscopic severe mucosal atrophy indicates the presence of gastric cancer after
Helicobacter pylori eradication -Analysis based on the Kyoto classification
Version: 1Date: 20 May 2020
Reviewer's report:
After HP eradication it is difficult distinguish normal mucosa and gastric cancer endscopically,
because of covering with normal differentiated epithelium. Therefore authors tried to identify theendoscopic findings based on Kyoto classification after HP eradication.
Authors analyzed the endoscopic findings based on Kyoto classification and concluded atrophy
score 2 is marker to predict the presence of gastric cancer.
But this finding is not novel.
It is natural that gastric mucosal atrophy is a risk factor for gastric cancer with or without HPeradication.In this analysis, there is no significant difference between cancer group and normal group in theduration after HP eradication. It is not important that no significant difference between cancer andnormal group but the difference between the second half and the first half (for example) includingcancer and normal group. Author should analyse the data on this point
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
YesAre the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
YesAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
Not relevant to this manuscript
Quality of written English
Please indicate the quality of language in the manuscript:
AcceptableDeclaration of competing interests
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