Review for 10.1186/s12876-019-1096-8 (2019)

Reviewer’s report
Title: Indications for adjuvant chemotherapy in patients with AJCC stage IIa T3N0M0 and T1N2M0
gastric cancer—an east and west multicenter study
Version: 0 Date: 29 Jul 2019
Reviewer: Jianxian Lin
Reviewer's report:
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 The manuscript BMGE-D-19-00501 "Indications for adjuvant chemotherapy in patients with AJCC
(7th ed.) stage IIa T3N0M0 and T1N2M0 gastric cancer -an east and west, multicenter study" analyzed
1593 patients from SEERdatabase and validation using FJUUH and IMIGASTRIC paitents. They
found that T3N0M0 and T1N2M0 gastric cancer patients should be treated with ajuvant chemotherapy,
especially for high-benefit patients. This is an interesting study. In Japanese guidline, the T3N0M0 and
T1N2M0 paitents were not recommended for AC. So the authors investigated these patients and found
the effect of AC in these patients. It is a well writen manuscript. There were some minor comments:
    1. The 7th and newest 8th edtion of AJCC TNM stage system is the same in stage IIa, so in the title,
the 7th ed. should be delete.
    2. There were several limitation in this study, the authors need to recommend in the discussion.
    3. The figure 2 and 3 should change to white blackground.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
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Yes
Are the conclusions drawn adequately supported by the data shown?
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Yes
Are you able to assess any statistics in the manuscript or would you recommend an additional
statistical review?
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assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Acceptable
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