Review for 10.1186/s12876-022-02151-x (2022)

Reviewer’s report
Title: 
Characteristics and potential malignancy of colorectal juvenile polyps in
adults: A single-center retrospective study in China
Version: 
0 
Date: 
16 Dec 2021
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
OBJECTIVE - Full research articles: is there a clear objective that addresses a
testable research question(s) (brief or other article types: is there a clear
objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols)
appropriate for the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor
to allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results
reasonable and not overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work
technically sound? If not, can revisions be made to make the work technically
sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: 
The authors report a series of patients with juvenile colorectal polyps. Overall,
they have good data, but my comments include:
1.The English language has to be improved. 
2. In the Abstract, they do not need to go into so much detail about a single
patient.
3. The abstract needs to be improved. The description of results and conclusions
needs to be better explained. 
4. 
The background and the gap in the literature about these polyps need to be
better explained in Introduction. What is missing in the literature? 
5. In Methods, JPS needs to be spelled out.
6. The last sentence of conclusion needs to be more original. 
7. The Discussion is written very well. 
I would also emphasize the additional
knowledge gained by this study that was not reported before.
Overall, the Methods, Results, and Discussion sections of the paper have been
well-written. 
The authors should revise Abstract and Introduction to the same
level.
ADDITIONAL REQUESTS/SUGGESTIONS: 
They should focus on the Abstract and the Introduction.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes