Review for 10.1186/s12876-019-0978-0 (2019)

Reviewer ’s report  
 
Title: Vitamin K deficiency -induced hemorrhagic shock after thoracentesis: A case report  
 
Version: 0 Date: 30 Mar 2018  
 
Reviewer: Silvia Martin Bielsa  
 
Reviewer's report:  
 
The authors present a clinical case entitled: "Vitamin K deficiency induced haemorrhagic shock 
after thoracentesis: a case report". The case is relevant. However, I believe that this paper would 
be improved if the authors would consider the following:  
 
1. The authors should specify the value of coagulation tests (activated partial thromboplastine 
time...) before and after the haemorrhagic complication and in blood examination on day four.  
 
2. How much pleural fluid was evacuated on days 13 and 17? Which was the procedure used to 
drain the pleural fluid? Did they use ultrasound to lead the procedures? They should specify 
these details and the biochemical characteristics of the pleural fluid.  
 
3. Figures 1 -4 are redundant; I think t hat only one or two should be selected.  
 
4. The authors conclude, "When thoracentesis is performed, abnormalities in the path of the 
intercostal artery should be identified". What do the authors propose to do? I think the most 
important conclusion is the m easurement of coagulation function and supplementations of 
vitamin K are necessary in high -risk patients, as the authors suggest too.  
 
 
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Decl aration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publication of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I  declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests  
 
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