Review for 10.1186/s12876-022-02439-y (2022)

Reviewer’s report
Title: 
Subcutaneous administration, higher age and lower renal function are associated with erythrocyte
methotrexate accumulation in Crohn’s disease: a cross-sectional study
Version: 
1 
Date: 
13 Jun 2022
Reviewer: 
Masaru Shinozaki
Reviewer's report:
I think it's OK to publish.
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Is the study design appropriate to answer the research question (including the use of appropriate controls),
and are the conclusions supported by the evidence presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free from apparent
manipulation?
Yes