Review for 10.1186/s12876-021-01685-w (2021)

Reviewer’s report
Title: 
Development and validation of a simple-to-use nomogram to predict liver
metastasis in patients with pancreatic neuroendocrine neoplasms: a large cohort
study
Version: 
0 
Date: 
25 Sep 2020
Reviewer: 
Research Square Reviewer 1
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
OBJECTIVE - Full research articles: is there a clear objective that addresses a
testable research question(s) (brief or other article types: is there a clear
objective)?
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols)
appropriate for the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with technical rigor
to allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results
reasonable and not overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Is the current version of this work
technically sound? If not, can revisions be made to make the work technically
sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: 
The study is very interesting , well conducted, and well written. All sections are
clear and well written; the limitations of the study were well analyzed.
ADDITIONAL REQUESTS/SUGGESTIONS: 
It would be useful to add to low and high risk scores , also a medium risk
category.
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Declaration of competing interests
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. 
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Do you have any non-financial competing interests in relation to this
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interests' below. If your reply is yes to any, please give details below.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes