Review for 10.1186/s12876-020-01521-7 (2020)

Reviewer’s report
Title: 
Serum Hydroxybutyrate dehydrogenase as an early predictive marker of
the severity of acute pancreatitis: a retrospective study
Version: 
1 
Date: 
06 Oct 2020
Reviewer's report:
I was happy on the alteration made by the authors according to my previous
comments, especially on the addition of CRP and Ca++ data and the AUC curve.
For other issues I understand they are difficult to be improved due to the study's
retrospective nature. The paper is close to get published.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes