Review for 10.1186/s12876-019-0968-2 (2019)

Reviewer ’s report  
 
Title:  A retrospective clinical and microbial analysis of 32 patients with bil omas  
 
Version: 0 Date: 26 Dec 2018 
 
Reviewer:  Jianfeng  Yang  
 
Reviewer’s report:  
 
Overall impression:  
 
This paper has a complete structure, clear thinking and novel themeSpecific comments:  
 
1. Whether to use antibiotics before collecting bile, how to ensure the reliability of results if 
antibiotics are used ?  
 
2. It is suggested to quantify the microorganism in bile and determine the number of 
microorganism  
 
3. It is generally considered that normal human bile is sterile ，Why are there bacteria in the 
bile of patients with bilomas?  
 
4. Why are there drug -resistant bacteria in patients with bilomas ?  
 
Are the methods appropriate a nd well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review  is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I recommend additional statistical review  
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Needs som e language corrections before being published  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication of this m anuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for pat ents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the  above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
NO 
 
I agree to the open peer review policy of the journal. I understand that my name will be included 
on my re port to the authors and, if the manuscript is accepted for publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
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CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any comments 
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to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal