Review for 10.1186/s12876-021-01713-9 (2021)

Reviewer’s report
Title: 
Expression of Cyr61 is associated with Clinical Course in Patients with
Crohn’s Disease
Version: 
1 
Date: 
06 Oct 2020
Reviewer's report:
This is an interesting paper examining the expression of Cysteine-rich
angiogenic inducer 61 (Cyr61) in patients with Crohn's disease. The paper is
well designed, constructed and presented. It clearly demonstrates that there is an
inverse association between its mucosal expression immunohistochemically and
the clinical course of the disease. It is of interest that this may have possible
therapeutic implications in the future. 
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Is the study design appropriate to answer the research question (including the use
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