Review for 10.1186/s12876-021-01711-x (2021)

Reviewer’s report
Title: 
First-line oral antiviral therapies showed similar efficacies in suppression
of serum HBcrAg in chronic hepatitis B patients
Version: 
4 
Date: 
18 Jan 2021
Reviewer's report:
Thank you for the authors' effort to revise the manuscript according to my
review. In my opinion, this manuscript was well modified for publication
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes