Review for 10.1186/s12876-021-01844-z (2021)

Reviewer’s report
Title: 
Tumor-to-tumor metastasis of diffuse large B cell lymphoma to gastric
adenocarcinoma via CXCL12 (SDF-1)/CXCR4 axis: a case report
Version: 
0 
Date: 
16 Apr 2021
Reviewer's report:
The full text has been read. Your article reports a case of tumor-to-tumor
metastasis of diffuse large B cell lymphoma to gastric adenocarcinoma and
suggests that the CXCL12 (SDF-1)/CXCR4 axis is involved in tumor-tumor
metastasis from DLBCL to primary gastric adenocarcinoma.
This report is good, but there are still some problems that need to be solved.
First of all, the article reads: Further, it should be noted that gastric lymphoma in
our case may not be a primary but metastatic tumor. If the premise "may" was
not true, this report would be meaningless. It is necessary to confirm the source
of DLBCL from a stomach biopsy.
Secondly, although the structure of this case report is complete, the content of
the pathological biopsy and the annotations of the illustrations are still thin. As
for the content of the discussion and conclusion part, it is not comprehensive
enough. It only reported the results. It would be great if the case report could be
supplemented for clinical practice, research significance, prospects, and
challenges.
Furthermore, the number of references is too small, and the key core documents
and reviews on the CXCL12 (SDF-1)/CXCR4 axis are not covered. If some
relevant basic research content is added, it will support the conclusions more
fully.
Finally, you need to pay attention to the grammar of your article.
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