Review for 10.1186/s12876-022-02275-0 (2022)

Reviewer’s report
Title: 
Burden and Trend of Colorectal Cancer in 54 countries of Africa 2010-
2019: A systematic examination for Global Burden of Disease
Version: 
0 
Date: 
16 Jan 2022
Reviewer's report:
Thank you for the possibility to review your paper. 
The paper provides interesting data on the burden of a neoplastic disease with a
very high prevalence worldwide, and address a part of the world where sanitary
data are scarce and often unreliable due to social and economica factors.
Therefore the contribution of the study to the knowledge of such problem is very
important, even if it is based on already available data. 
The language request an extensive revision. 
Furthermore, the limitations of the study are not clearly addressed. Some of them
are related to the socio-economic conditions of the countries studied, and can be
easily presumed, but their impact on the data should be better analyzed.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
No
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes