Review for 10.1186/s12876-021-02034-7 (2022)

Reviewer’s report
Title: 
Effect of Helicobacter pylori infection on malignancy of undifferentiated-
type gastric cancer
Version: 
1 
Date: 
14 Oct 2021
Reviewer: 
Naoki Hashimoto
Reviewer's report:
Author writes "Eradication did not completely eliminate the risk of cancer even
after a long period of time.( Take et al ). In clinical data, The proportion of
patients with UD-GC was 14.3% in the group with eradicated Hp.
I ask question to author. Why UD-GC occured fiver year s later after
eradication? Author says "UD-GC origin from the deeper mucosal layer and
extends through the deeper mucosal layer running laterally, it may take some
time before the tumor is exposed on the mucosal surface, and can be detected by
endoscopy." I agree to author's opinion.
I think author's data is "Eradication did not completely eliminate the risk of
cancer even after a long period of time".
I think that Endscopic ultrasonography is necessary for eary detection. How
about my opinion?
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