Review for 10.1186/s12876-020-01473-y (2020)

Reviewer’s report
Title:  Infection deteriorating hepatitis B virus related acute-on-chronic liver failure: a retrospective
cohort study
Version: 0 Date: 16 Aug 2020
Reviewer's report:
This is an interesting article, discussing the incidence and impact of infection in HBV related ACLF.
Manuscript is well written, with 2 comments and recommendation in results chapter
In table 2, the values between brackets in WBC count, CRP, and PCT are not defined; are they 95% CI
of those values or something else. This needs to be keyed below the table.
Figure 2B is not clear as there are multiple lines and the difference between different lines in legend is
not clear in B&amp;W image
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Is the study design appropriate to answer the research question (including the use of appropriate
controls), and are the conclusions supported by the evidence presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are  the  images  in  this  manuscript  (including  electrophoretic  gels  and  blots)  free  from  apparent
manipulation?
Yes