Review for 10.1186/s12876-022-02209-w (2022)

Reviewer’s report
Title: 
Magnifying endoscopic findings of early-stage poorly differentiated
colorectal adenocarcinoma: a case report
Version: 
1 
Date: 
15 Dec 2021
Reviewer's report:
This manuscript is interesting because early-stage poorly differentiated colorectal
adenocarcinoma is very rare. However, we need to evaluate few points about
endoscopic images before adoption.
In NBI magnifying observation (Figure 1B), I could not judge vessel pattern
(dence, irregular, corkscrew-like microvessels) because of low-power
magnification. 
In magnifying endoscopy with crystal violet staining (Figure 1C,1D), I could
not judge that the lesion had really stainless feature because the back ground
mucosa also showed a little pale dyed color (please refer to [reference 2-4]).
I want to change NBI image to more high-power magnification image.
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Is the study design appropriate to answer the research question (including the use
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