Review for 10.1186/s12876-020-01336-6 (2020)

Reviewer ’s report  
 
Title: Short -course Rifaximin therapy efficacy and Lactulose H ydrogen Breath Test in Chinese  
patients with Diarrhea -Predominant Irritable Bowel Syndrome  
 
Version: 0 Date: 26 Mar 2020  
 
Reviewer: Renato Bocchini  
 
Reviewer's report:  
 
There is a major defect: th e authors extend rifaximin results to all patients with ibs d, while they 
should talk only about pts with sibo and ibs or better differentiate the two groups (ibsd with sibo 
and ibsd without sibo). therefore they should change methods and conclusions, and may be even 
the title.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your com ments to the authors.  
 
No 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical r eview?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
 
Quality of written English  
Please indicate the quality of language in the man uscript:  
 
Acceptable  
 
 
 
 
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