Review for 10.1186/s12876-021-01695-8 (2021)

Reviewer’s report
Title: 
Vaping-Associated Esophagitis: Case Report
Version: 
0 
Date: 
29 Jan 2021
Reviewer's report:
The authors presented an interesting case of the patient with severe esophagitis
who had recent history of vaping.
The manuscript is well written, and has clinical meaning about the association
between vaping and esophagitis. 
I have some comments. 
1. The patient underwent endoscopic biopsy. Is there no evidence suggesting
Barrett's esophagus in the specimen? In addition, I think it is more helpful to add
histologic figure for the readers.
2. The author suggested that vaping decreases lower esophageal sphincter tone
and causes severe esophagitis. Is there other possibility of the cause of severe
esophagitis (e.g., direct esophageal mucosal damage associated with vaping gas
inhalation, like oral ulcer or erosion)?
3. The patient recently started vaping THC and nicotine. Do you think which is
more harmful factor in this case?
Thank you.
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