Review for 10.1186/s12876-020-01523-5 (2020)

Reviewer’s report
Title: 
Adding ursodeoxycholic acid to the endoscopic treatment and common
bile duct stenting for large and multiple biliary stones: will it improve the
outcomes?
Version: 
0 
Date: 
01 Oct 2020
Reviewer's report:
This is an RCT that examined the usefulness of UDCA treatment for large and
multiple biliary stones, and it is a very interesting article. 
I don't think there are any major issues with study design or contents of
discussion. 
Minor revision: 
1. Are yes and no reversed at stone removal in Table 1? Please check. 
2. Please specify in the text that Group A is the control group in the Table. It's a
little confusing.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes