Review for 10.1186/s12876-021-01645-4 (2021)

Reviewer’s report
Title: 
Polygenic Risk Score is a Predictor of Adenomatous Polyps at Screening
Colonoscopy
Version: 
0 
Date: 
06 Sep 2020
Reviewer: 
Shahram Agah
Reviewer's report:
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Dear Authors,
Thank you for your interesting topic and good writing
1. I suggest GRS be a key word
2. Table 1: No polyps + positive for polyps' total percent should be 100%,
Should not?
3. 
Table 2: hyperplastic polyp is zero?
4. Supplementary table 1: Are there any commercial test or at least
internationally acceptable tests for diagnosis of these SNPs or they are only
available in research labs?
5. The SNP measurements is not the base of this study; however, I believe that it
is reasonable to explain in a few sentences as the base of this study
6. As the most of authors are clinicians it is worth mentioning that to explain in a
few sentence the clinical use of their findings
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
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