Review for 10.1186/s12876-022-02109-z (2022)

Reviewer’s report
Title: 
Lobaplatin hyperthermic intraperitoneal chemotherapy plus cytoreduction
and rechallenge using cetuximab for wild-type RAS peritoneal metastatic colon
cancer: a case report and literature review
Version: 
1 
Date: 
26 Nov 2021
Reviewer's report:
This is an interesting case report regarding lobaplatin hyperthermic
intraperitoneal chemotherapy plus cytoreduction and rechallenge using
cetuximab for wild-type RAS peritoneal metastatic colon cancer
I have the following comments:
The aim of the study must be specified in the introduction
Please add the limitations of the study and a brief sentence regarding future
perspectives
The references section must be improved by adding some references on the
topic:
- Microsatellite and RAS/RAF Mutational Status as Prognostic Factors in
Colorectal Peritoneal Metastases Treated with Cytoreductive Surgery and
Hyperthermic Intraperitoneal Chemotherapy (HIPEC). Ann Surg Oncol. 2021
Nov 16. doi: 10.1245/s10434-021-11045-3. Epub ahead of print. PMID:
34783946.
- Systematic review of published literature on oxaliplatin and mitomycin C as
chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in
patients with peritoneal metastases from colorectal cancer. Crit Rev Oncol
Hematol. 2019 Oct;142:119-129. doi: 10.1016/j.critrevonc.2019.06.014. Epub
2019 Jul 9. PMID: 31400583
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
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from apparent manipulation?
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