Review for 10.1186/s12876-017-0647-0 (2017)

Reviewer ’s report  
 
Title: Lichenoid esophagitis presenting as fatal upper gastrointestinal bleeding in a 52 year -old 
woman. Rep ort of a case diagnosed by autopsy  
 
Version: 0 Date: 03 Jan 2017  
 
Reviewer: Luca Mastracci  
 
Reviewer's report:  
 
This case report describes a 'lichenoid e sophagitis', causing death for massive bleeding. The case 
is well presented, with beautiful histology images and with an adequate discussion.  
 
The pattern of 'lichenoid esophagitis' is well known but often underdiagnosed. The main novelty, 
never reported be fore, is the esophageal ulceration with massive bleeding causing death.  
 
Limitations of microscopy on autopsy material are underlined and stressed(lines 137 -168); this 
part could be shortened.  
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comme nts to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical r eview?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
Not relevant to this manuscript  
Quality of written English  
Please indicate the quality of language in the man uscript:  
 
Acceptable  
 
 
 
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publi cation of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests' below  
 
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on my report to the authors and, if the manuscript is accepted for publication, my named repo rt 
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I agree to the open peer review policy of the journal