Review for 10.1186/s12876-020-01256-5 (2020)

Reviewer’ s report
Title: Prostaglandin E-major urinary metabolite versus fecal immunochemical occult blood test as
a biomarker for patient with ulcerative colitis
Version: 1Date: 03 Dec 2019
Reviewer: Sakiko Hiraoka
Reviewer's report:
The authors investigated the usefulness of Prostaglandin E-major urinary metabolite (PGE-MUM)
for a biomarker for ulcerative colitis (UC) patients. To use in actual clinical practice, it wasnecessary to present sensitivity, specificity, PPV , NPV , accuracy using ROC analysis. Pleaseanalysis them of eMES 0 vs. eMES1-3 and eMES 0,1 vs. eMES 2,3. If there are too many figures,the authors should consider to delate the figures about CAI vs. biomarkers.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
YesDoes the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
NoAre you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?If an additional statistical review is recommended, please specify what aspects require furtherassessment in your comments to the editors.
Not relevant to this manuscriptQuality of written English
Please indicate the quality of language in the manuscript:
AcceptableDeclaration of competing interests
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