Review for 10.1186/s12876-020-01229-8 (2020)

Reviewer ’s report  
 
Title: Serum amyloid A is a better predictive biomarker of mucosal healing than C -react ive 
protein in ulcerative colitis in clinical remission  
 
Version: 1 Date: 28 Sep 2019  
 
Reviewer: Shunji Ishihara  
 
Reviewer's report:  
 
The authors responded well to this reviewer's comments. Following are the minor comments for 
the authors.  
 
1. The results analyzed for revised manuscript were not sufficiently described in the 
Results section of text. In particular, the results regarding supplementary Tables and 
Figures should be simply described in the text.  
 
2. Supplemental Figure F (right panel ): A p -value in the Biologics ( -) group was 0.00832. 
This result seems significant.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify  which controls are required in your comments to the authors.  
 
Unable to assess  
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manusc ript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please speci fy what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1.  Have you in the past five year s received reimbursements, f ees, funding, or salary 
from an organisation that may in any way gain or lose financial ly from the 
publication of this manuscript, either now or in the future?  
 
2.  Do you hold any stocks or shares in an organisation that may in a ny way gain or 
lose financially from the publication of this manuscript, either now or in the 
future?  
 
3.  Do you hold or are you currently applying for any patents  relating to the content 
of the manuscript?  
 
4.  Have you received reimbursements, fees, funding , or salary from an organization 
that holds or has applied for patents relating to the content of the manuscript?  
 
5.  Do you have any other financial competing interests?  
 
6.  Do you have any non -financial competing interests in relation to this paper?  
 
If you  can answer no to all of the above, write 'I declare that I have  no competing interests' 
below. If your reply is yes to any, please give details below.  
 
'I declare that I have no competing interests.  
 
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on my report to the authors and, if the manuscript is accepted f or publication, my named report 
including any attachments I upload will be posted on the website along with the authors' 
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CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understand that any  comments 
which I do not wish to be included in my named report can be in cluded as confidential comments 
to the editors, which will not be published.  
 
I agree to the open peer review policy of the journal