Review for 10.1186/s12876-017-0730-6 (2017)

Reviewer ’s report  
 
Title: A rare cause of acute liver failure - a case report  
 
Version: 0 Date: 26 Nov 2017  
 
Reviewer: Conrado Fernandez Rodriguez  
 
Reviewer's report:  
 
This is an illustrative case report of a middle -aged female presenting with acute liver failure due 
to a massive hepatic sinusoidal infiltration by a late relapsing infiltrating ductal breast cancer. 
There are to few cases published from solid mali gnancies as cause of ALF.  
 
Minor  
1. Was transjugular liver biopsy considered in this case?. Do you think a more aggressive 
therapeutic approach once the diagnosis would have been reached would have change the 
outcome?. Please, discuss  
2. Please, change F ulvestran for Fulvestrant throughout the manuscript.  
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the  editors.  
 
Not relevant to this manuscript  
 
 
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of c ompeting interests, considering the following questions:  
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organisation that may in any way gain or lose financially from the publication of this 
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3. Do you hold or are you currently applying for any patents relating t o the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you  have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing interest  
 
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