Review for 10.1186/s12876-023-02850-z (2023)

Reviewer’s report
Title: 
SMC1A facilitates gastric cancer cell proliferation, migration and invasion
via promoting SNAIL activated EMT
Version: 
0 
Date: 
24 Nov 2022
Reviewer's report:
This article is a molecular biological study investigating the association between
structural maintenance of chromosomes protein 1A (SMC1A) and gastric cancer
invasion and prognosis. The concept of this study is good. Please provide
additional information on the relationship between SMC1A expression and
prognosis in gastric cancer (In page 7, line 44-59). How were the 875 cases
described in Kaplan-Meier collected and searched for SMC1A, and how were
high and low expression of SMC1A defined? Please describe them in the method
section.
MinorPlease spell out some abbreviations (ex. EMT, SNAIL) in the beginning
of the manuscript.
Declaration of competing interests
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes
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No