Review for 10.1186/s12876-019-1083-0 (2019)

Reviewer’s report
Title: Prognoses of different pathological subtypes of colorectal cancer at different stages: A 
population-based retrospective cohort study
Version: 0 Date: 23 Jul 2019
Reviewer: Takuma Higurashi
Reviewer's report:
This population-based retrospective cohort study concluded that the patients of different pathological 
subtypes were only minimally different at the early stage. However, they were significantly different 
prognosis and patients with MAC and SRCC have worse OS and CCS, which are mainly in advanced 
CRC (stages III and IV).
This is well written study and novel information, however, this study has some limitations in the 
following areas.
 
<Major＞
1. One of the strength of this study is large sample, however, excluded people are too many. The study 
that contains many excluded may have some biases. The authors should minimize the exclusion.
<Minor>
1.  The manuscript needs editing by a native English speaker.
Are the methods appropriate and well described?
If not, please specify what is required in your comments to the authors.
Yes
Does the work include the necessary controls?
If not, please specify which controls are required in your comments to the authors.
Yes
Are the conclusions drawn adequately supported by the data shown?
If not, please explain in your comments to the authors.
Yes
Are you able to assess any statistics in the manuscript or would you recommend an
additional statistical review?
If  an  additional  statistical  review  is  recommended,  please  specify  what  aspects  require  further
assessment in your comments to the editors.
I am able to assess the statistics
Quality of written English
Please indicate the quality of language in the manuscript:
Needs some language corrections before being published
Declaration of competing interests
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