Review for 10.1186/s12876-021-01703-x (2021)

Reviewer’s report
Title: 
Liver Transplantation in Adult Polycystic Liver Disease: The Ontario Experience.
Version: 
0 
Date: 
16 Dec 2020
Reviewer: 
Salvatore Gruttadauria
Reviewer's report:
The manuscript is updated and readable, but a description of graft allocation strategy related to recipient
signs & symptoms is needed especially defining patients' characteristics and early clinical outcomes. 
The authors should revise their report and include the following aspects:
# Major issues
- Did the authors consider an allocation priority score for this etiology?
- How did the authors consider the nutritional support prior of transplantation? How did this direct their
clinical management? The order of events and the decision-making regarding this are not fully clear from
the report. 
- Description of surgical techniques in terms of inferior caval vein anatomy, of surgical experience and
skills, usage of machine perfusion device for reducing ischemia reperfusion injuries of kidney grafts, and
liver preservation solutions during the back table time.
# Minor observations
- If present, what were their differences in harvesting maneuvers in their experiences, such as juxtarenal
caval vein anatomy? 
- Was the presence of the abnormalities of vein anatomy considered prior of cross-clamping or during the
back table surgery? 
- Was severe graft congestion and massive bleeding from the transection surface noted at reperfusion
time?
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Is the study design appropriate to answer the research question (including the use of appropriate controls),
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Yes
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Yes
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