Review for 10.1186/s12876-018-0806-y (2018)

Reviewer ’s report  
 
Title: Clinical Outcomes of Endoscopic Mucosal Resection for Rectal Neuroendocrine Tumor  
 
Version: 1 Date: 08 Mar 2018  
 
Reviewer: Masau Sekiguchi  
 
Reviewer's report:  
 
This is my second review of this manuscript.  
Although the manuscript has substantially improved, it still has fundamental problems as 
follows.  
1. As the authors agreed, the insufficient efficacy of EMR has already been reported in many 
previous studies a nd this study seems to have confirmed the already -known findings. 
Although this study showed some new findings, such as relatively high H -CR rate of 
conventional EMR and relatively low H -CR rate of modified EMR, the clinical impact of 
these findings seems to be low.  
 
2. It is well known that there have been few previous reports of rectal NETs with long follow -
up period. However, the study aim and design should be considered apart from these 
situations. If the aims of the study include evaluation of recurre nce of rectal NETs, I 
recommend the authors to evaluate it several years later.  
Are the methods appropriate and well descri bed?  
If not, please specify what is required in your comments to the authors.  
 
No 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
No 
 
Are the conclusions drawn adequately suppo rted by the data shown?  
If not, please explain in your comments to the authors.  
 
No 
 
  
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please s pecify what aspects require further  
assessment in your comments to the editors.  
 
I recommend additional statistical review  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publi cation of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
I declare that I have no competing interests.  
 
I agree to the open peer review policy of the journal. I understand that my name will be included  
on my report to the authors and, if the manuscript is accepted for publication, my named rep ort 
including any attachments I upload will be posted on the website along with the authors'  
responses.  I agree for my report to be made available under an Open Access Creative Commons 
CC-BY license ( http://creativecommons.org/licenses/by/4.0/ ). I understa nd that any comments 
which I do  not wish to be included in my named report can be included as confidential comments 
to the  editors, which will not be published.  
 
I agree to the open peer review policy of the journal