Review for 10.1186/s12876-017-0591-z (2017)

Reviewer ’s report  
 
Title:  The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in 
patients with Crohn's dis ease 
 
Version: 0 Date: 02 Mar 2016 
 
Reviewer:  Humberto  Jijon  
 
Reviewer’s report:  
 
I like the study.  It is  clear and does not over -reach in its conclusions.  It lays the basis for future 
work, perhaps a multicenter study with a greater number of patients.  One of the strengths is the 
use of the Behcet's group, it will be interesting to see if the differences s een between BS and CD 
stand up to a multicenter trial.   
 
There are a few typos that need to be corrected but otherwise I feel the study should be accepted 
without major revisions or additional analysis.  
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an 
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further 
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please i ndicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an 
organisation that may in any way gain or lose financially from the publication of this 
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2. Do you hold any stocks or shares in an organisation that may in any way gain or lose 
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you currently applying for any patents relating to the content of the 
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below. If your reply is yes to any, please give details below.  
 
I declare that I have no competing intere sts 
 
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to the editors, which will not be published . 
 
I agree to the open peer review policy of the journal