Review for 10.1186/s12876-018-0858-z (2018)

Reviewer ’s report  
 
Title: Suspected Drug -induced Liver Injury Associated with Iguratimod: A Case Report and  
Review of the Literature  
 
Version: 2 Date: 20 Mar 2018  
 
Reviewer: Rolf Teschke  
 
Reviewer's report:  
Please include all comments for the authors in this box rather than uploading your report as an 
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The section of causality assess ment is still not acceptable. Naranjo is obsolete and should be 
removed from the text and reference list. Instead, a more recent reference of the updated 
RUCAM should be quoted and discussed: Danan G, Teschke R. RUCAM in drug and herb 
induced liver injury:  The update. Int J  
Mol Sci 2016; 17 (1), 14. DOI: 10.3390/ijms17010014.  
 
Page 1 line 31, RUCAM should read: the updated RUCAM.  
 
Discussion: page? line 39 correct please to idiosyncratic. Line 50, please change CIOMS to 
RUCAM and expand also the abbreviat ion. Line 45, RUCAM is the most commonly ...add 
reference of the updated RUCAM here. Page? line 1 "tired of oil" please clarify. Section before 
para: starting with "Understanding..." add references of the updated RUCAM.  
 
Abbreviation setior line 53: r -GPT,  please correct to: gamma -... 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
No 
Does the work include the necessary controls?  
If not, p lease specify which controls are required in your comments to the authors.  
Yes 
Are the conclusions drawn adequately supported by the data shown?  
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Yes 
Are you able to assess any statistics i n the manuscript or would you recommend an 
additional statistical review?  
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assessment in your comments to the editors.  
I am able to assess the statistics  
Quality  of written English  
Please indicate the quality of language in the manuscript:  
Acceptable  
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