Review for 10.1186/s12876-021-01643-6 (2021)

Reviewer’s report
Title: 
Expression and Prognostic Impact of FZDs in Pancreatic Adenocarcinoma
Version: 
0 
Date: 
08 Nov 2020
Reviewer's report:
This manuscript has studied the prognostic impact of FZDs in PAAD. This
manuscript is interesting and well written. However, it will require some revision
before publication.
1. Please summarize figures.
2, Figure 5 shows univariate analysis of each FZDs on OS and RFS in PAAD.
How was multivariate analysis on OS and RFS in PAAD?
3, How do the authors treat PAAD with FZD4 and 8?
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
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Yes
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Yes
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from apparent manipulation?
Yes