Review for 10.1186/s12876-020-01358-0 (2020)

Reviewer ’s report  
 
Title: Increased Incidence of Metachronous Gastric Neoplasm After Endoscopic Resection in  
Patients With Synchronous Gastric Neoplasm  
 
Version: 2 Date: 19 May 2020  
 
Reviewer's report:  
 
1. Please read again the instructions for authors and prepare the manuscript accordingly. There is 
no sec tion 'Aim' in the Abstract in the instruction. Please remove 'Aim' and revise the abstract.  
 
2. I don't understand the reponse to the comment #4 of the reviewer #3.  
"We actually excluded the cases of non -curative resection in the analysis. The patients wit h non -
curative resection underwent additional surgical resection, which was the policy of our hospital 
during the study period."  
Although surgical resection is recommended for non -curative endoscpoic resection of gastric 
cancer, there are patients who do n ot undergo surgery because of various reasons. So, I doubt 
that all patients with non -curative endoscopic resection underwent additional surgical resection 
in the authors' institution. In addition, surgery is not always recommended after non -curative 
resec tion of gastric adenoma. So, I think the authors should explain clearly this point again.  
 
If the authors excluded all cases with non -curative endoscopic resection, please revise the 
Methods accordingly. Also, the description on the number of excluded pat ients and reasons in 
the Results and the Fig 1. should be revised accordingly.  
 
3. Method, page 6, lines 3 - 4 
 
"Of these patients, 228 patients were excluded due to..."  
-> "...511 patients..."  
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your c omments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in yo ur comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the manuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in y our comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Acceptable  
 
Declaration of competing interests  
Please complete a declaration of competing interests, considering the following questions:  
 
1. Have you in the past five years received reimbursements, fees, funding, or salary from an  
organisation that may in any way gain or lose financially from the publi cation of this  
manuscript, either now or in the future?  
 
2. Do you hold any stocks or shares in an organisation that may in any way gain or lose  
financially from the publication of this manuscript, either now or in the future?  
 
3. Do you hold or are you curr ently applying for any patents relating to the content of the  
manuscript?  
 
4. Have you received reimbursements, fees, funding, or salary from an organization that 
holds  or has applied for patents relating to the content of the manuscript?  
 
5. Do you have any  other financial competing interests?  
 
6. Do you have any non -financial competing interests in relation to this paper?  
 
If you can answer no to all of the above, write 'I declare that I have no competing interests' 
below.  If your reply is yes to any, please give details below.  
 
No COI  
 
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Access  Creative Commons CC -BY Lice nse ( http://creativecommons.org/licenses/by/4.0 ) if this 
manuscript  is accepted for publication. Any comments that I do not wish to be included in the 
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I agree to the terms of the CC -BY 4.0 license; please do not publish my name with my report.  
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