Review for 10.1186/s12876-018-0751-9 (2018)

Reviewer ’s report  
 
Title: Hepatitis C -related cryoglobulinemic neuropathy: potential role of oxcarbazepine for pain  
control  
 
Version: 0 Date: 29 Dec 2017  
 
Reviewer: Theodoros Androutsakos  
 
Reviewer's report:  
 
Overall a good effort. However it needs to be revised as language is concerned (t.ex. it is not 
with sustained THE viral response, just sustained viral response) and I think you need to show us 
some more data about the HCV status of the patients included in this study (viral load and 
genotype). Moreover you are saying that 44 patients interrupted their treatment due to adverse 
effects. I would like to know what kind of adverse effects were these. 11 of your patients are said 
to have stopped treatment due to neuropathy ,so they should not be included in this study since 
your patients have HCV related and not interferon related neuropathy. Last but not least looks 
like 50% of your patients have also HBV infection ,unless what you mean is they had previous 
HBV infection, so I would like you to comment on that as well.  
 
 
 
 
Are the methods appropriate and well described?  
If not, please specify what is required in your comments to the authors.  
 
Yes 
 
Does the work include the necessary controls?  
If not, please specify which controls are required in your comments to the authors.  
 
Yes 
 
Are the conclusions drawn adequately supported by the data shown?  
If not, please explain in your comments to the authors.  
 
Yes 
 
Are you able to assess any statistics in the ma nuscript or would you recommend an  
additional statistical review?  
If an additional statistical review is recommended, please specify what aspects require further  
assessment in your comments to the editors.  
 
I am able to assess the statistics  
 
Quality of written English  
Please indicate the quality of language in the manuscript:  
 
Not suitable for publication unless extensively edited  
 
 
 
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