Review for 10.1186/s12876-021-02018-7 (2021)

Reviewer’s report
Title: 
Endoscopic negative pressure therapy as stand-alone treatment for
perforated duodenal diverticulum – presentation of two cases
Version: 
1 
Date: 
26 Aug 2021
Reviewer's report:
This is a case report that endoscopic negative pressure therapy was effective for
perforated duodenal diverticulum. As the authors mentioned, these cases are
meaningful as one of the treatments for perforated duodenal diverticulum.
However, it may be difficult to understand the explanation about OPSD and
ENPT especially for the non-experienced readers. The followings may be taken
into consideration.
In the line 87, please explain the structure and establishment of OPSD with the
figures if possible.
In the line 88 and 89, what size is a cut piece of the film? How and where did
you placed the tube? Please show the methods with the figures if possible.
In the line 95, why are the changes of the system required? What is the timing
to change it?
Please use double line spacing.
Please spell out the abbreviations in the tables.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
No
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
Yes
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes