Review for 10.1186/s12876-022-02348-0 (2022)

Reviewer’s report
Title: 
Utility of mean platelet volume in differentiating intrahepatic
cholangiocarcinoma from hepatocellular carcinoma
Version: 
1 
Date: 
18 Apr 2022
Reviewer's report:
PEER REVIEWER ASSESSMENTS: 
OBJECTIVE - Full research articles: is there a clear objective that addresses one
or several testable research questions? (Brief or other article types: is there a
clear objective?)
Yes - there is a clear objective
DESIGN - Is the current approach (including controls and analysis protocols)
appropriate for the objective?
Yes - the approach is appropriate
EXECUTION - Are the experiments and analyses performed with sufficient
technical rigor to allow confidence in the results?
Yes - experiments and analyses were performed appropriately
STATISTICS - Is the use of statistics in the manuscript appropriate?
Yes - appropriate statistical analyses have been used in the study
INTERPRETATION - Is the current interpretation/discussion of the results
reasonable and not overstated?
Yes - the author's interpretation is reasonable
OVERALL MANUSCRIPT POTENTIAL - Has the author addressed your
concerns sufficiently for you to now recommend the work as a technically sound
contribution? If not, can further revisions be made to make the work technically
sound?
Probably - with minor revisions
PEER REVIEWER COMMENTS: 
GENERAL COMMENTS: My main concerns have been addressed 
by the
authors and appropriate changes. For me the amendments have improved the
manuscript but the 
re are still grammatical errors throughout the paper that do
make it difficult to read.
ADDITIONAL REQUESTS/SUGGESTIONS: 
As mentioned earlier, a native english speaker review again of the main text will
help in readability. 
Otherwise, the authors have written a good response letter and some of the
points raised and analysed ie APRI, FIB4, NLR I would recommend to be
introduced in to the main manuscript too.
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Is the study design appropriate to answer the research question (including the use
of appropriate controls), and are the conclusions supported by the evidence
presented?
Yes
Are the methods sufficiently described to allow the study to be repeated?
Yes
Is the use of statistics and treatment of uncertainties appropriate?
Yes
Is the presentation of the work clear?
No
Are the images in this manuscript (including electrophoretic gels and blots) free
from apparent manipulation?
Yes