Review for 10.1186/s12876-023-02768-6 (2023)

Reviewer’s report
Title: 
Risk stratification based on acute-on-chronic liver failure in
cirrhotic patients hospitalized for acute variceal bleeding
Version: 
0 
Date: 
09 Jan 2023
Reviewer's report:
The Authors demonstrated that Acute on Chronic Liver Failure is a risk factor of
mortality in pazientes bleeding from varices. The CLIF.C ACLF score was
compared to MELD, MELD-Na, and Child Pugh score and resulted superior to
predicts prognosis in Cirrhotic patients with variceal bleeding. They analysed
417 records from MIMIN.IV database of patients admitted in ICU The 52% of
patients presented ACLF. This number is quite high compared to the study of
Shin et al. including also patients not admitted to ICU.
Was ACLF present in the same amount in the 129 patients of your group not
admitted to ICU. Comment on this point
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