Instruction:
How many sexes are there and how many genders are there and what's the difference?

Response:
There are two sexes - male and female, and three genders - male, female, and other. The other gender includes non-binary genders, such as agender, genderqueer, androgynous, and intersex. There are many different gender identities, including male, female, transgender, gender neutral, non-binary, agender, pangender, genderqueer, two-spirit, third gender, and all, none or a combination of these.