Instruction:
What is the Genomie Aggregation Databaise (genomAD)?

Response:
The Genome Aggregation Database (genomAD) is a large-scale database of genetic variation data that aggregates and harmonizes genetic data from multiple population genetics studies. The database was created by the Broad Institute of MIT and Harvard in collaboration with other research institutions, and it contains genomic data from over 140,000 individuals from diverse populations around the world. The goal of genomAD is to provide a comprehensive resource for the study of genetic variation, allowing researchers to identify rare and common variants, assess their frequency in different populations, and analyze their potential effects on human health and disease. GenomAD includes both exome and whole-genome sequencing data, and it is widely used in genomics research and clinical genomics applications.