Question: how long does it take to cook a 2 pound brisket in the oven?
Answer: Preheat oven to 300° and place a rack inside the large roasting pan. ...  Place the brisket, fat cap up, in the middle of aluminum foil prepared in the roasting pan. ...  UPDATE: Place in the oven and bake for about 1 hour and 15 minutes per pound, until the brisket reaches about 180°.