Question: how to unlock binding of isaac items?
Answer: Azazel: Satanic Bible. Active item. ...  Blue Baby: D6. Active item. ...  Cain: Sack of Pennies. Passive item. ...  Eden: Blank Card. Active item. ...  Isaac: Isaac's Tears. Active item. ...  Judas: Guillotine. ...  Lazarus: Lazarus' Rags. ...  The Lost: Isaac's Heart.