Title: Asteroid hyalosis

{{Infobox medical condition (new)
| name            = Asteroid hyalosis
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| image           = Asteroid hyalosis 3.JPG
| caption         = Asteroid hyalosis in a [[Yorkshire Terrier]]
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| field           = [[Ophthalmology]]
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'''Asteroid hyalosis''' is a degenerative condition of the [[eye]] involving small white [[Opacity (optics)|opacities]] in the [[vitreous humor]].&lt;ref&gt;Mishra C, Tripathy K. [https://pubmed.ncbi.nlm.nih.gov/32119262/ Asteroid Hyalosis]. 2023 Jul 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32119262.&lt;/ref&gt;  It is known to occur in humans, [[dog]]s, [[cat]]s, [[horse]]s, and [[chinchilla]]s.&lt;ref&gt;{{cite journal |vauthors=Wang M, Kador P, Wyman M |title=Structure of asteroid bodies in the vitreous of galactose-fed dogs |journal=Mol Vis |volume=12 |pages=283–9 |year=2006 |pmid=16617295}}&lt;/ref&gt;  Clinically, these opacities are quite refractile, giving the appearance of stars shining in the night sky—except that ocular asteroids are often quite mobile.  Ocular asteroids must be distinguished from the more common typical vitreous [[floater]]s, which are usually fibrillar or cellular condensates.  The cause of asteroid hyalosis is unknown, but it has been associated with [[diabetes mellitus]],&lt;ref&gt;{{cite journal | vauthors = Akram A, Niazi M, Ishaq M, Azad N | title = Frequency of diabetics in asteroid hyalosis patients. | journal = J Ayub Med Coll Abbottabad | volume = 15 | issue = 3 | pages = 10–1 | year = 2003| pmid = 14727330}}&lt;/ref&gt; [[hypertension]], [[hypercholesterolemia]],&lt;ref&gt;{{cite journal | vauthors = Bergren R, Brown G, Duker J | title = Prevalence and association of asteroid hyalosis with systemic diseases. | journal = Am J Ophthalmol | volume = 111 | issue = 3 | pages = 289–93 | year = 1991 | pmid = 2000898 | doi=10.1016/s0002-9394(14)72311-6}}&lt;/ref&gt; and, in certain animals, tumors of the [[ciliary body]].&lt;ref name=Gelatt_1999&gt;{{cite book|editor=Gelatt, Kirk N.|title=Veterinary Ophthalmology|edition=3rd|publisher=Lippincott, Williams &amp; Wilkins|year=1999|isbn=0-683-30076-8}}&lt;/ref&gt;  In dogs, asteroid hyalosis is considered to be an age-related change.&lt;ref&gt;{{cite web | last = Bjerk | first = Ellen | title = Ocular Disease of the Aging Dog | work = Proceedings of the 29th World Congress of the World Small Animal Veterinary Association | year = 2004 | url = http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2004&amp;PID=8721&amp;O=Generic | access-date = 2007-03-23 }}&lt;/ref&gt;  The '''asteroid bodies''' are made up of hydroxyapatite, which in turn consists of [[calcium]] and [[phosphates]] or [[phospholipid]]s.&lt;ref&gt;{{cite journal | vauthors = Komatsu H, Kamura Y, Ishi K, Kashima Y | title = Fine structure and morphogenesis of asteroid hyalosis. | journal = Med Electron Microsc | volume = 36 | issue = 2 | pages = 112–9 | year = 2003 | pmid = 12825125 | doi = 10.1007/s00795-002-0211-y| s2cid = 8506875 }}&lt;/ref&gt;  While asteroid hyalosis does not usually severely affect vision, the floating opacities can be quite annoying, and may interfere significantly with visualization and testing of the [[retina]].&lt;ref&gt;{{cite journal | vauthors = Wong S, Sampath R | title = Erroneous automated refraction in a case of asteroid hyalois. | journal = J Cataract Refract Surg | volume = 28 | issue = 9 | pages = 1707–8 | year = 2002 | pmid = 12231337 | doi = 10.1016/S0886-3350(01)01224-X}}&lt;/ref&gt;  While treatment of asteroid hyalosis is usually unnecessary, [[vitrectomy]] may occasionally be indicated, for both diagnostic and therapeutic purposes.&lt;ref&gt;{{cite journal | vauthors = Olea Vallejo J, Muñoz Corrales E, Mateos Poch J, Mulet Perera P, Suñer Capo M | title = [Vitrectomy for asteroid hyalosis] | journal = Arch Soc Esp Oftalmol | volume = 77 | issue = 4 | pages = 201–4 | year = 2002 | pmid = 11973661}}&lt;/ref&gt;&lt;ref&gt;{{cite journal | vauthors = Feist R, Morris R, Witherspoon C, Blair N, Ticho B, White M | title = Vitrectomy in asteroid hyalosis. | journal = Retina | volume = 10 | issue = 3 | pages = 173–7 | year = 1990 | pmid = 2236940 | doi=10.1097/00006982-199001030-00003| s2cid = 22582315 }}&lt;/ref&gt;

==See also==
* [[Synchysis scintillans]]

==References==
{{Reflist}}

== External links ==
{{Medical resources
|  DiseasesDB     = 32877
|  ICD10          = {{ICD10|H|43|2}}
|  ICD9           = {{ICD9|379.22}}
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{{DEFAULTSORT:Asteroid Hyalosis}}
[[Category:Dog diseases]]
[[Category:Eye diseases]]