Title: Subvalvular aortic stenosis (canine)

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Canine '''subvalvular aortic stenosis''' (SAS) is an abnormal, [[congenital heart defect|congenital]] [[heart murmur]] caused by subaortic [[stenosis]] (SAS).

This genetic trait is [[polygenic]], and in some cases asymptomatic. An animal with SAS may offspring and show no symptoms of the stenosis until multiple generations which is why it is advised not to breed an animal diagnosed with SAS.&lt;ref&gt;{{Cite news|url=http://www.akc.org/content/health/articles/heart-murmur-in-dogs/|title=Heart Murmur in Dogs |last=Burke |first=Anna | name-list-style = vanc |work=American Kennel Club|access-date=2018-02-12|language=en}}&lt;/ref&gt;

== Symptoms ==
Puppies and adult dogs diagnosed with subaortic [[stenosis]] can suffer from a range of clinical signs such as fainting, breathing difficulty in the moderate cases or heart failure and sudden death in severe cases.&lt;ref&gt;{{Cite web |title=Aortic/subaortic stenosis |url=https://www.vet.cornell.edu/hospitals/services/cardiology/aorticsubaortic-stenosis |website=College of veterinary medicine}}&lt;/ref&gt; Symptoms also include sudden/strong [[lethargicism]], continuous heavy panting, and a rise in temperature.

== Diagnosis == 

The [[Orthopedic Foundation for Animals]] (OFA) has established a Congenital Heart Registry whose guidelines were established by veterinary cardiologists. A dog which [[Auscultation|auscultates]] normally at 12 months of age is considered to be free of [[congenital heart disease]]. Upon confirmation of this, OFA will issue a certificate.&lt;ref&gt;{{Cite web |title=Cardiac disease |url=https://ofa.org/diseases/cardiac-disease/ |website=ofa.org}}&lt;/ref&gt;

== References ==
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[[Category:Dog diseases]]