Title: White dog shaker syndrome

{{short description|Disease in dogs}}
'''White dog shaker syndrome''' (also known as '''idiopathic steroid responsive shaker syndrome''', '''shaker dog syndrome''', '''&quot;little white shakers&quot; syndrome''' and '''idiopathic cerebellitis''') causes full body tremors in small dog breeds. It is most common in [[West Highland White Terrier]]s, [[Maltese dog|Maltese]], [[Bichon]]s, [[Poodle]]s,&lt;ref name=Etiinger_1995&gt;{{cite book|author=Ettinger, Stephen J.|author2=Feldman, Edward C.|title=Textbook of Veterinary Internal Medicine|edition=4th|publisher=W.B. Saunders Company|year=1995|isbn=0-7216-6795-3}}&lt;/ref&gt; and other small dogs.  There is a sudden onset of the disease at one to two years of age.  It is more likely to occur, and the symptom is worse during times of [[Stress (physiology)|stress]].  [[pathologic nystagmus|Nystagmus]], difficulty walking, and [[seizure]]s may occur in some dogs.

The cause is unknown, but it may be mediated by the [[immune system]].  One theory is that there is an [[autoimmunity|autoimmune]]-induced generalized deficiency of [[neurotransmitter]]s.&lt;ref&gt;{{cite web | title = What is shaker dog syndrome? | work = Canine Inherited Disorders Database | publisher = University of Prince Edward Island | date = 2001 | url = https://www.upei.ca/~cidd/Diseases/nervous%20system%20disorders/shaker%20dog%20syndrome.htm | accessdate = 2007-02-12 }}&lt;/ref&gt;  [[Cerebrospinal fluid]] analysis may reveal an increased number of [[lymphocyte]]s.&lt;ref name=Vite&gt;{{cite web|author=Vite, C.H.|year=2005|title=Inflammatory Diseases of the Central Nervous System|work=Braund's Clinical Neurology in Small Animals: Localization, Diagnosis and Treatment|url=https://www.ivis.org/advances/Vite/braund27/chapter_frm.asp?LA=1#Shaker|accessdate=2007-02-13}}&lt;/ref&gt;  Treatment with [[corticosteroid]]s may put the dog into [[remission (medicine)|remission]], or [[diazepam]] may control the symptoms.&lt;ref name=Chrisman_2003&gt;{{cite book|author=Chrisman, Cheryl|author2=Clemmons, Roger|author3=Mariani, Christopher|author4=Platt, Simon|title=Neurology for the Small Animal Practitioner|edition=1st|publisher=Teton New Media|year=2003|isbn=1-893441-82-2}}&lt;/ref&gt;  Typically the two drugs are used together.&lt;ref&gt;{{cite journal |vauthors=Yamaya Y, Iwakami E, Goto M, Koie H, Watari T, Tanaka S, Takeuchi A, Tokuriki M |title=A case of shaker dog disease in a miniature dachshund |journal=J Vet Med Sci |volume=66 |issue=9 |pages=1159–60 |year=2004 |pmid=15472486 |doi=10.1292/jvms.66.1159|doi-access=free }}&lt;/ref&gt;  There is a good [[prognosis]], and symptoms usually resolve with treatment within a week, although lifelong treatment may be necessary.&lt;ref name=Vite/&gt;

==References==
{{reflist}}

[[Category:Steroid-responsive inflammatory conditions]]
[[Category:Syndromes in dogs]]

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