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Question: What is your opinion of the "out of box" picture and color quality?  Does it take much tweaking to make things look good?
Document: Even the asus demo monitors in best buy don't have hot menu button temperatures.Asus makes good mobo, video cards, and sound cards, but monitors they make have poor quality control. I would suggest to any wanting buy this monitor look LG or Samsung monitors instead. Avoid Asus monitors cause you will end up exchanging them because of the poor quality control. ***update***Found the problem the button that is brightness/up function is super hot 107.9*F it does not work.
I'm in love with this monitor. I mounted it on my wall immediately after opening the box so I can't speak much on the stand (although it is obviously aesthetically pleasing and seems to be of solid construction), but the monitor itself is gorgeous. No dead pixels, and a perfect image after about a half hour of toying with the calibration. I use it mainly for music production so I'm constantly staring at small text and waveforms, so clarity and sharp color contrast was a must.
I got my display today. It has a single dead pixel (only the red part) which is unnoticeable unless you are looking at a red screen. Asus has a 7 day warranty that covers any dead pixels but I'm just going to keep it as I haven't noticed it when in actual use.The picture quality is excellent, glare reduction is great without sacrificing picture quality. If you don't want to get into the price range of the 2560x1440 displays this is the one to get.
EDIT (UPDATED 6/2/2014)Pros - I absolutely love the design of this Asus monitor. The outer bezel is very thin and aesthetically pleasing. The stand that came with it is very sturdy although I immediately removed it to mount it on my monitor stand.Picture is awesome!CONSI ordered 2 of these monitors and both arrived with a single dead pixel. To troubleshoot to make sure the pixels were in fact dead and not stuck I ran UDpixel on the area for an hour, no luck.
You may need to tweak the color settings to your liking but once you've done that you'll love the monitor. It has low GTG for gaming, great viewing angels, and a super thin bezel if you're hooking up more than one for a Eyefinity or similar desktop.
If you are not looking for this picture, I won't recommend this monitor.
I'm sitting here looking at the MacBook monitor and the ASUS monitor side by side and there is no comparison. The MacBook is sharp and clear, the ASUS not. I don't think it would matter much if you're using Quickbooks on a Windows computer, but if you are doing graphics on a Mac this monitor will be a great disappointment. Too bad, I thought it was going to be long term on my desktop.
I looked at a ton of 27&#34; monitor reviews on every brand imaginable on both here and newegg and bestbuy. I went as far as to goto Bestbuy and look at the selection they had on hand. I ran across this monitor on the Asus web site and liked the fact it had alot of different input options as well as 5ms speed and it is able to turn 90 degress.
No dead pixels so far. Picture is beautiful in 1080p. Sound is decent for the few games and slingbox i'll be watching. There are a bunch of screen modes for normal, landscape, sRGB, games, etc.There are adjustments to turn 90 degrees, move left/right, tilt top/bottom and move up/down.
The monitor did arrive with one or two dark pixels which was a disappointment as I do a lot of photo editing and bad pixels make it more difficult. Maybe I have just been lucky, but this is the first of several digital monitors I have had which came with a bad pixel. It also does not come with a manual, just a very basic setup diagram in multiple languages, but no spec sheet, etc.
Answer: I didn't tweak much at all. I was content with the out of box picture but most importantly I LOVE this monitor and I'd recommend it 10 times over.