Compound: RIMEXOLONE
SMILES: O=C1C=C2[C@]([C@H]3[C@@H](O)C[C@@]4([C@](C(=O)CC)(C)[C@@H](C[C@H]4[C@@H]3CC2)C)C)(C)C=C1
InChIKey: QTTRZHGPGKRAFB-OOKHYKNYSA-N
Synonyms: RIMEXOLONE, 49697-38-3, Vexol, Org-6216, Rimexolon, Rimexolona, Rimexolonum, O7M2E4264D, (11beta,16alpha,17beta)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one, RefChem:56796, H02AB12, S01BA13, 11 beta-hydroxy-16 alpha,17 alpha,21-trimethylpregna-1,4-diene-3,20-dione, (11 beta,16 alpha,17 beta)-11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one, (1S,2R,10S,11S,13R,14S,15S,17S)-17-hydroxy-2,13,14,15-tetramethyl-14-propanoyltetracyclo(8.7.0.02,?.011,1?)heptadeca-3,6-dien-5-one, DTXCID2025474, DTXSID4045474, Org 6216, MLS002154105, (1S,2R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1,2,9a,11a-tetramethyl-1-propanoyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one, Trimexolone, Rimexel, 11beta-Hydroxy-16alpha,17alpha-dimethyl-17-propionylandrosta-1,4-dien-3-one, (8S,9S,10R,11S,13S,14S,16R,17S)-11-hydroxy-10,13,16,17-tetramethyl-17-propanoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one, Org 6216; Rimexel, Rimexolonum [INN-Latin], Rimexolona [INN-Spanish], UNII-O7M2E4264D, Rimexolone [USAN:USP:INN:BAN], Vexol (TN), AL 02178, RIMEXOLONE [MI], Rimexolone (USP/INN), RIMEXOLONE [INN], Prestwick0_001020, Prestwick1_001020, Prestwick2_001020, Prestwick3_001020, RIMEXOLONE [USAN], RIMEXOLONE [VANDF], RIMEXOLONE [MART.], RIMEXOLONE [USP-RS], RIMEXOLONE [WHO-DD], BSPBio_001179, SCHEMBL445300, SPBio_003050, BPBio1_001297, GTPL7099, orb1695466, CHEMBL1200617, RIMEXOLONE [ORANGE BOOK], RIMEXOLONE [USP IMPURITY], CHEBI:135566, HMS1571K21, HMS2098K21, HMS2235B18, HMS3715K21, RIMEXOLONE [USP MONOGRAPH], HY-B1754, 11beta-Hydroxy-16alpha,17,21-trimethyl-1,4-pregnadien-3,20-dion, BDBM50103606, EBC-26827, EX-A10694, MSK011032, AKOS040753759, AL-2178, CCG-221020, DB00896, FR27734, MSK011032-100A, NCGC00179273-01, (8S,9S,10R,11S,13S,14S,16R,17S)-11-hydroxy-10,13,16,17-tetramethyl-17-propionyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one, DA-77465, SMR001233413, AB00514006, CS-0013781, D05729, Rimexolone Solution in Acetonitrile, 100ug/mL, EN300-24730386, SR-01000841221, Q7334443, SR-01000841221-2, BRD-K31627533-001-03-8, BRD-K31627533-001-09-5, (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one, (11beta, 16alpha, 17beta)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androstra-1,4-dien-3-one, ANDROSTA-1,4-DIEN-3-ONE, 11-HYDROXY-16,17-DIMETHYL-17-(1-OXOPROPYL)-, (11.BETA.,16,ALPHA.,17.BETA.)-, Androsta-1,4-dien-3-one, 11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)-, (11beta,16alpha,17beta)-
Theoretical properties:
molecular_formula: C24H34O3
molecular_weight: 370.5 g/mol
exact_mass: 370.25079494 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 2
heavy_atom_count: 27
topological_polar_surface_area: 54.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: Insoluble
Descriptions:
pubchem: Rimexolone is a 20-oxo steroid.
chembl: RIMEXOLONE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye. It is marketed as a 1% eye drop suspension under the trade name Vexol by Alcon Laboratories, but was discontinued in the US and other countries.