Compound: urea
SMILES: O=C(N)N
InChIKey: XSQUKJJJFZCRTK-UHFFFAOYSA-N
Synonyms: urea, 57-13-6, carbamide, Carbonyldiamide, Ureophil, Carbonyldiamine, Ureaphil, Keratinamin, Urevert, Alphadrate, Aquadrate, Carbaderm, Pastaron, Urepearl, Carbonyl diamide, Carbamide resin, Ultra Mide, Varioform ii, Aqua Care, Harnstoff, Mocovina, Nutraplus, Prespersion, 75 urea, Supercel 3000, Aqua Care HP, Ureacin-10 lotion, Ureacin-40 Creme, Caswell No. 902, NCI-C02119, Antisepsis bolus, Elaqua xx, Sterile Urea, EPA Pesticide Chemical Code 085702, AI3-01202, Azodicarboxylic acid-diamide, NSC-34375, INS NO.927A, E927b, INS-927A, E-927A, 8W8T17847W, CHEBI:16199, NSC34375, Lanaphilic, Flexifoot, Flexitol, Protexa, Vanamide, UterCleanse, Xurea, Balneum plus, Umecta Mousse, Sential e, Cem-urea, St.james balm, Urea Foam, Hydromol intensive, Cracked Skin Cream, Umecta Mousse Urea, Urea 40 Percent, RYNODERM, 20% Urea Cream, Urea 39% Cream, Urea Cream 40%, Urea Cream 41%, Clear 40, Urea 40 Nail Gel, Bare 40 Plus HA, Clear 50 Nail Gel, Urea 40 Plus HA, Clear 40 Plus HA, HEEL BALM, CLEAN-UP, Bare 20, Bare 40, RefChem:6696, Urea 20, Urea 40, Bare 40 HA, Bare 40 SA, URE-K, Urea Cream 40 Percent, INTRAUTERINE BOLUS, Urea 41%, Nekvnro 20% Urea Cream, Drymatine 20% Urea Cream, Kp Exfoliating Repair Cream, Urea 39.5%, iShanCare Cracked Skin Cream, URE-39, UREA 40%, Joypretty Kp Exfoliating Repair Cream, 200-315-5, 682-045-1, Isourea, Carbamimidic acid, B-I-K, basodexan, carmol, Ureacin-20, Aquacare, Panafil, Hyanit, Carbonyl Diamine, CCRIS 989, aminoketone, HSDB 163, Ureum, Carbamimic acid, Bubber shet, Keratinamin Kowa, NSC 34375, Benural 70, 37955-36-5, DTXSID4021426, UR, Urea-18O, Carbamide;Carbonyldiamide, MFCD00008022, (NH2)2CO, Urea, prilled, NCGC00090892-01, M02656, Mocovina [Czech], 3138-51-0, 4744-36-9, URE, Harnstoff [German], DTXCID901426, Urea [JAN], CAS-57-13-6, Urea [USP:JAN], UREA, ACS, EINECS 200-315-5, uree, Isoharnstoff, Cerovel, Karbamid, Urepeal, Uroderm, amino ketone, amino-ketone, Urea perhydrate, Pastaron soft, Urea, ultrapure, Aquacare HP, UNII-8W8T17847W, Urepeal L, Carbamide solution, Urea (Standard), beta-I-k, Pastaron 10, Pastaron 20, Pastaron (TN), Pastaron 20 soft, Urea CRS, carbonamidimidic acid, Carmol 40, Cerovel (Salt/Mix), Panafil (Salt/Mix), Rubinol ST 010, Urea, p.a., Optigen 1200, Urea, 2M, Spectrum_000672, UREA [VANDF], WLN: ZVZ, Carbamimidic acid (VAN), Spectrum2_001192, Spectrum3_001791, Spectrum4_001168, Spectrum5_001862, Urea (JP18/USP), Urea, analytical standard, Urea, for electrophoresis, UREA [HPUS], UREA [HSDB], Urea (8CI,9CI), UREA [FCC], UREA [USP-RS], UREA [WHO-DD], Eucerin 10% Urea Lotion, CHEMBL985, UREA [II], UREA [MART.], UREA [MI], EC 200-315-5, SCHEMBL4441, UREA [ORANGE BOOK], H2N-CO-NH2, H2NC(O)NH2, UREA [EP MONOGRAPH], UREA [USP IMPURITY], Urea A.C.S. reagent grade, H2N-C(OH)=NH, SCHEMBL26926, BSPBio_003341, KBioGR_001775, KBioSS_001152, U-CORT COMPONENT UREA, UREA [USP MONOGRAPH], Urea, puriss., 99.5%, MLS001076688, DivK1c_000086, H2N-C(=NH)-OH, HO-C(=NH)-NH2, SCHEMBL168109, SCHEMBL506209, SPECTRUM1500604, Urea, AR, >=99%, Urea, LR, >=99%, SPBio_001263, ALPHADERM COMPONENT UREA, GTPL4539, orb1310336, orb3140420, SCHEMBL1531371, SCHEMBL1673179, CARMOL HC COMPONENT UREA, SCHEMBL12100926, SCHEMBL29360205, SCHEMBL30068375, Urea, >=99.0%, Urea, Molecular Biology Reagent, BDBM24961, CHEBI:48376, HMS500E08, HY-Y0271R, KBio1_000086, KBio2_001152, KBio2_003720, KBio2_006288, KBio3_002843, CALMURID HC COMPONENT UREA, Urea 100 microg/mL in Methanol, NINDS_000086, HMS1921I17, HMS2092C08, HMS2232P21, HMS5081B20, Pharmakon1600-01500604, component of Artra Ashy Skin Cream, CS-B1800, HY-Y0271, STR00449, Urea, tested according to Ph.Eur., Tox21_111036, Tox21_202158, Tox21_300035, c0165, CCG-40265, EBC-03021, MSK005142, NSC757375, s3687, STL194286, Urea, ReagentPlus(R), >=99.5%, AKOS009031424, Urea, NIST(R) SRM(R) 2141, Urea, SAJ first grade, >=98.0%, DB03904, FU35121, NSC-757375, Urea, JIS special grade, >=99.0%, Urea, meets USP testing specifications, Urea, Vetec(TM) reagent grade, 99%, IDI1_000086, NCGC00090892-02, NCGC00090892-03, NCGC00090892-04, NCGC00090892-05, NCGC00090892-06, NCGC00254181-01, NCGC00259707-01, SMR000499585, Urea, ACS reagent, 99.0-100.5%, Urea, mole-ready, A.C.S. reagent grade, ALLANTOIN IMPURITY B [EP IMPURITY], SBI-0051552.P002, Urea, BioReagent, suitable for cell culture, FLUOROURACIL IMPURITY G [EP IMPURITY], NS00001564, T0738, U0073, U0077, Urea, ReagentPlus(R), >=99.5%, pellets, EN300-19456, C00086, component of Artra Ashy Skin Cream (Salt/Mix), D00023, D70446, Q48318, Urea, p.a., ACS reagent, 99.0-100.5%, AB00052123_05, SR-01000762961, InChI=1/CH4N2O/c2-1(3)4/h(H4,2,3,4, SR-01000762961-2, Urea Working Standard (Secondary Reference Standard), Urea, British Pharmacopoeia (BP) Reference Standard, BRD-K88052444-001-08-8, Fluorouracil EP Impurity G; Allantoin EP Impurity B, Urea, European Pharmacopoeia (EP) Reference Standard, F0001-1490, Urea, BioUltra, for molecular biology, >=99.5% (T), Urea, BioXtra, pH 7.5-9.5 (20 C, 5 M in H2O), Urea, NIST SRM 2152, combustion calorimetric standard, Urea, United States Pharmacopeia (USP) Reference Standard, 6E4EB293-4363-4D38-BF3B-1397372C31E5, Urea, 8 M (after reconstitution with 16 mL high purity water), Urea, puriss. p.a., ACS reagent, reag. Ph. Eur., >=99.5%, Urea, Pharmaceutical Secondary Standard; Certified Reference Material, Urea, powder, BioReagent, for molecular biology, suitable for cell culture
Theoretical properties:
molecular_formula: CH4N2O
molecular_weight: 60.056 g/mol
exact_mass: 60.032362755 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 0
heavy_atom_count: 4
topological_polar_surface_area: 69.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: White crystals or powder
color: White crystals or powder
odor: MAY GRADUALLY DEVELOP SLIGHT ODOR OF AMMONIA, ESP IN PRESENCE OF MOISTURE
boiling_point: Decomposes (NTP, 1992)
melting_point: 275 °F (NTP, 1992)
density: 1.34 at 68 °F (USCG, 1999) - Denser than water; will sink
solubility: Soluble (NTP, 1992)
vapor_pressure: 0.000012 [mmHg]
Descriptions:
{"pubchem": "Urea is a carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). It has a role as a fertilizer, a flour treatment agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a Daphnia magna metabolite. It is a monocarboxylic acid amide and a one-carbon compound. It is functionally related to a carbonic acid. It is a tautomer of a carbamimidic acid.", "chebi": "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O).", "chembl": "UREA is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.", "wikipedia": "Urea, also called carbamide (because it is a diamide of carbonic acid), is an organic compound with chemical formula CO(NH2)2. This amide has two amino groups (\u2212NH2) joined by a carbonyl functional group (\u2212C(=O)\u2212). It is thus the simplest amide of carbamic acid.\nUrea serves an important role in the cellular metabolism of nitrogen-containing compounds by animals and is the main nitrogen-containing substance in the urine of mammals. The word urea is Neo-Latin, from French  ur\u00e9e, from Ancient Greek  \u03bf\u1f56\u03c1\u03bf\u03bd (o\u00fbron) 'urine'.\nIt is a colorless, odorless solid, highly soluble in water, and practically non-toxic. Dissolved in water, it is neither acidic nor alkaline. The body uses it in many processes, most notably nitrogen excretion. In the liver, it forms by the condensation of ammonia (NH3) and carbon dioxide (CO2) in the urea cycle. Urea is widely used in fertilizers as a source of nitrogen (N).\nIn 1828, Friedrich W\u00f6hler discovered that urea can be produced from inorganic starting materials, an important conceptual milestone in chemistry. This showed for the first time that a substance previously known only as a byproduct of life could be synthesized in the laboratory from non-biological starting materials, thereby contradicting the widely held doctrine of vitalism, which stated that organic compounds could only be derived from living organisms."}