Compound: Methadyl acetate
SMILES: O=C(OC(C(c1ccccc1)(c2ccccc2)CC(N(C)C)C)CC)C
InChIKey: XBMIVRRWGCYBTQ-UHFFFAOYSA-N
Synonyms: Methadyl acetate, Acetylmethadol, Acetilmetadol, Acetylmethadolum, 509-74-0, 3-Acetoxy-6-dimethylamino-4,4-diphenylheptane, L59OC40KWJ, ACSCN-9601, IDS-NA-004, NIH-2953, Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), DTXSID2023274, 6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate, 6-(Dimethylamino)-4,4-Diphenyl-3-Heptanol Acetate, RefChem:156848, DTXCID403274, 208-103-4, Acetilmetadol [INN-Spanish], Acetylmethadolum [INN-Latin], Methadyl acetate [USAN], Acemethadone, Acetylmethadol (INN), Acetylmethadol [INN], 6-(Dimethylamino)-4,4-diphenyl-3-heptanol acetate (ester), Methadyl acetate (USAN), race-Acetylmethadol, CHEMBL170179, EINECS 208-103-4, 1-Ethyl-4-dimethylamino-2,2-diphenylpentylacetat, UNII-L59OC40KWJ, (R,S)-4-Dimethylamino-1-ethyl-2,2-diphenylpentyl acetat, DEA No. 9601, ORLAAM (Salt/Mix), l-.alpha.-Acetylmethadol, Levo-.alpha.-acetylmethadol, MK 790 (Salt/Mix), (-)-.alpha.-Acetylmethadol, METHADYL ACETATE [MI], SCHEMBL119911, 4-(Dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate, CHEBI:135491, BDBM50027391, DB01433, NS00067937, Levomethadyl acetate hydrochloride (Salt/Mix), D04973, L000758, Q4673310, O-ACETYL-6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEPTANOL, Acetic acid 4-dimethylamino-1-ethyl-2,2-diphenyl-pentyl ester, 4-(Dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate, (3S,6S)-(-)-, Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-diphenyl-pentyl ester, Benzeneethanol, .beta.-((2S)-2-(dimethylamino)propyl)-.alpha.-ethyl-.beta.-phenyl-, acetate (ester), (.alpha.S)-, BENZENEETHANOL, .BETA.-(2-(DIMETHYLAMINO)PROPYL)-.ALPHA.-ETHYL-.BETA.-PHENYL-, ACETATE (ESTER), Benzeneethanol, .beta.-[2-(dimethylamino)propyl]-.alpha.-ethyl-.beta.-phenyl-, acetate (ester), [S-(R*,R*)]-
Theoretical properties:
molecular_formula: C23H31NO2
molecular_weight: 353.5 g/mol
exact_mass: 353.235479232 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 9
heavy_atom_count: 26
topological_polar_surface_area: 29.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Acetylmethadol is a diarylmethane.
chembl: METHADYL ACETATE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Acetylmethadol, also known as methadyl acetate, is a synthetic opioid analgesic. It is a racemic mixture of alphacetylmethadol (α-acetylmethadol) and betacetylmethadol (β-acetylmethadol), which are in turn racemic mixtures of levacetylmethadol (LAAM; L-α-acetylmethadol) and D-α-acetylmethadol and L-β-acetylmethadol and D-β-acetylmethadol, respectively. Hence, acetylmethadol has four possible optical isomers. All of these isomers have been shown to partially or fully substitute for the discriminative stimulus effects of heroin in rats, and thus it can be inferred that, in addition to LAAM which is used clinically as such, they are all likely to be active opioid analgesics in humans.
In the United States, acetylmethadol and its individual isomers are all Schedule I drugs under the Controlled Substances Act, except LAAM, which is Schedule II and was used clinically until 2003.  Acetylmethadol has an ACSCN of 9601.  The isomers have individual ACSCNs, which are as follows: Alphacetylmethadol 9603, Betacetylmethadol 9607, LAAM 9648.  All of the above have annual manufacturing quotas of 2 grams as of 2013, except LAAM, which is 4 grams.