Compound: Opipramol
SMILES: OCCN1CCN(CCCN2c3c(C=Cc4c2cccc4)cccc3)CC1
InChIKey: YNZFUWZUGRBMHL-UHFFFAOYSA-N
Synonyms: Opipramol, 315-72-0, Opipramolum, Opipramol dura, 2-[4-(3-benzo[b][1]benzazepin-11-ylpropyl)piperazin-1-yl]ethanol, NSC-169867, D23ZXO613C, 4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazineethanol, 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol, 1-PIPERAZINEETHANOL, 4-(3-(5H-DIBENZ(b,f)AZEPIN-5-YL)PROPYL)-, DTXSID3023394, Opipramolo, 2-(4-(3-benzo(b)(1)benzazepin-11-ylpropyl)piperazin-1-yl)ethanol, RefChem:168394, DTXCID203394, N06AA05, 2-(4-(3-(2-azatricyclo(9.4.0.0^(3,8))pentadeca-1(15),3,5,7,9,11,13-heptaen-2-yl)propyl)piperazin-1-yl)ethan-1-ol, 206-254-0, Nisidana, Opipramol G, Opramidol, Endison, Insidon, base, NSC 169867, Insidon (free base), Pramolan (free base), CHEMBL370753, Opipramol (INN), 5H-Dibenz(b,f)azepine, 5-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-, MFCD00865455, N-(3-(4-(2-Hydroxyethyl)piperazino)propyl)iminostilbene, N-[3-[4-(2-Hydroxyethyl)piperazino]propyl]iminostilbene, GR 33040, OPIPRAMOL [INN], G 33040, Opipramol [INN:BAN], Opipramolum [INN-Latin], NCGC00162068-04, EINECS 206-254-0, BRN 0627076, UNII-D23ZXO613C, 2-(4-(3-(5h-dibenzo[b,f]azepin-5-yl)propyl)piperazin-1-yl)ethan-1-ol, 2-{4-[3-(5H-Dibenzo[b,f]azepin-5-yl)propyl]piperazin-1-yl}ethan-1-ol, Insidon (Salt/Mix), Opipramol (Standard), Opipramol  Free Base, Pramolan (Salt/Mix), OPIPRAMOL [MI], OPIPRAMOL [WHO-DD], Oprea1_247234, SCHEMBL49841, Opipramol, analytical standard, orb1688661, SCHEMBL29414094, CHEBI:94614, GTPL11247, 1-Piperazineethanol,4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-, BDBM50170636, EBC-13800, MSK161646, NSC169867, AKOS003588969, DB12930, FO26574, HY-118901R, SDCCGSBI-0633687.P001, NCGC00162068-01, NCGC00162068-02, NCGC00162068-05, NCGC00162068-09, AC-15972, DA-56474, MS-25790, HY-118901, 1-Piperazineethanol,f]azepin-5-yl)propyl]-, CS-0077653, NS00010442, WLN: T C676 BNJ B3-AT6N DNTJ D2Q, D08297, G78301, EN300-18531271, Q416562, BRD-K43786866-300-02-3, Z2216903864, N-[3-[4-(2-Hydroxyethyl)-piperazino]propyl]iminostilbene, 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazinethanol, 2-[4-(3-Dibenzo[b,f]azepin-5-yl-propyl)-piperazin-1-yl]-ethanol, 5H-Dibenz[b, 5-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-, 2-(4-[3-(5H-Dibenzo[b,f]azepin-5-yl)propyl]-1-piperazinyl)ethanol #, 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol, 2-{4-[3-(5H-dibenz[b,f]azepin-5- yl)propyl]piperazin-1-yl}ethanol, 2-{4-[3-(5H-dibenzo[b,f]azepin-5-yl)propyl]piperazin-1-yl}ethanol, 2-[4-(3-{2-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-yl}propyl)piperazin-1-yl]ethan-1-ol
Theoretical properties:
molecular_formula: C23H29N3O
molecular_weight: 363.5 g/mol
exact_mass: 363.231062557 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 6
heavy_atom_count: 27
topological_polar_surface_area: 30 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.
chembl: OPIPRAMOL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Opipramol, sold under the brand name Insidon among others, is an anxiolytic and tricyclic antidepressant that is used throughout Europe. Despite chemically being a tricyclic dibenzazepine (iminostilbene) derivative similar to imipramine, opipramol is not a monoamine reuptake inhibitor like most other tricyclic antidepressants, and instead acts primarily as a sigma-1 receptor agonist. It was developed by Schindler and Blattner in 1961.