Compound: salicylamide
SMILES: O=C(N)c1c(O)cccc1
InChIKey: SKZKKFZAGNVIMN-UHFFFAOYSA-N
Synonyms: salicylamide, 2-Hydroxybenzamide, 65-45-2, o-Hydroxybenzamide, 2-Carbamoylphenol, Benzamide, 2-hydroxy-, Salicylic acid amide, 2-Carboxamidophenol, Algiamida, Panithal, Oramid, Urtosal, Acket, Amidosal, Dolomide, Dropsprin, Liquiprin, Morsarinas, Raspberin, Saliamid, Saliamin, Salizell, Serramida, Algamon, Allevin, Anamid, Novecyl, Salicim, Salipur, Salrin, Salymid, Afko-Sal, Amid-Sal, Salicilamida, Benzamide, o-hydroxy-, Salicilamide, Salicylamidum, Cidal, Samid, H.P. 34, SR 4326, Benzoic acid, 2-hydroxy-, amide, NSC-3115, EM8BM710ZC, DTXSID3021726, DTXCID501726, CHEBI:32114, RefChem:6211, N02BA05, 200-609-3, Benesal, Salamid, Flarpirina, Andasol, Eggosalil, Salamide, MFCD00007978, 2-Hydroxy-benzamide, Amid kyseliny salicylove, OHB, NSC 3115, CHEMBL27577, MLS000069486, NCGC00091414-02, SMR000046394, Salicylamide 100 microg/mL in Acetonitrile, Salizell (VAN), Benesal (VAN), Salicilamide [DCIT], Salicilamide [Italian], Salicylamidum [INN-Latin], CAS-65-45-2, Salicilamida [INN-Spanish], CCRIS 6045, HSDB 227, Amid kyseliny salicylove [Czech], EINECS 200-609-3, UNII-EM8BM710ZC, BRN 0742439, Salicylamid, AI3-03454, hydroxy benzamide, dihydroxybenzalamine, Salicylamide [USP:INN:BAN:JAN], Salicylamide, 99%, Spectrum_000946, Salicylamide (Standard), Opera_ID_1684, Spectrum2_001312, Spectrum3_000564, Spectrum4_000499, Spectrum5_001032, SALICYLAMIDE [MI], WLN: ZVR BQ, SALICYLAMIDE [INN], SALICYLAMIDE [JAN], EC 200-609-3, SALICYLAMIDE [HSDB], NCIOpen2_001127, SALICYLAMIDE [VANDF], Oprea1_069894, SCHEMBL21646, BSPBio_001948, KBioGR_001017, KBioSS_001426, SALICYLAMIDE [MART.], 4-10-00-00169 (Beilstein Handbook Reference), Deferasirox Benzamide Impurity, DivK1c_000858, SALICYLAMIDE [USP-RS], SALICYLAMIDE [WHO-DD], SCHEMBL162829, SCHEMBL875217, SPECTRUM1500532, Salicylamide (JAN/USP/INN), SPBio_001403, benzenecarboxamide, 2-hydroxy-, orb1311036, SCHEMBL1975862, SCHEMBL4116744, SCHEMBL10915695, SCHEMBL11516367, SCHEMBL29384763, HMS502K20, HY-B0811R, KBio1_000858, KBio2_001426, KBio2_003994, KBio2_006562, KBio3_001448, NSC3115, NINDS_000858, HMS1920P14, HMS2092G15, HMS2232E07, HMS5085G18, Pharmakon1600-01500532, component of Tolagesic (Salt/Mix), HY-B0811, MSK11195, SALICYLAMIDE [USP MONOGRAPH], Tox21_111129, Tox21_201944, Tox21_302801, BBL016007, BDBM50056900, CCG-39250, EBC-03127, NSC757318, s6404, SBB058584, STK301812, AKOS000120983, Tox21_111129_1, CS-7630, DB08797, FS27782, NSC-757318, IDI1_000858, NCGC00091414-01, NCGC00091414-03, NCGC00091414-04, NCGC00091414-05, NCGC00091414-07, NCGC00256376-01, NCGC00259493-01, 287492-04-0, DS-16216, Salicylamide, puriss., >=99.0% (T), SY009157, SBI-0051509.P003, DB-269424, EU-0000058, NS00006293, S0006, ST45061688, EN300-18542, D01811, F85552, AB00052089_12, AH-034/32461056, F091532, SR-01000721923, BENZOIC ACID,2-HYDROXY,AMIDE   SALICYLAMIDE, Q2496906, SR-01000721923-2, BRD-K81130846-001-02-6, BRD-K81130846-001-12-5, BRD-K81130846-001-17-4, Z68590124, F0451-0020, 2,4-CYCLOHEXADIEN-1-ONE, 6-(AMINOHYDROXYMETHYLENE)-, Salicylamide, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10, Salicylamide, Pharmaceutical Secondary Standard; Certified Reference Material
Theoretical properties:
molecular_formula: C7H7NO2
molecular_weight: 137.14 g/mol
exact_mass: 137.047678466 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 1
heavy_atom_count: 10
topological_polar_surface_area: 63.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: WHITE OR SLIGHTLY PINK CRYSTALLINE POWDER
color: WHITE OR SLIGHTLY PINK CRYSTALLINE POWDER
boiling_point: 518 °F at 760 mmHg (decomposes) (NTP, 1992)
melting_point: 284 °F (NTP, 1992)
density: 1.175 at 284 °F (NTP, 1992) - Denser than water; will sink
solubility: less than 1 mg/mL at 68 °F (NTP, 1992)
Descriptions:
pubchem: Salicylamide is the simplest member of the class of salicylamides derived from salicylic acid. It has a role as a non-narcotic analgesic and an antirheumatic drug. It is a member of phenols and a member of salicylamides.
chebi: The simplest member of the class of salicylamides derived from salicylic acid.
chembl: SALICYLAMIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Salicylamide (o-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin.  Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid.  It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from
1960 to 1980 in conjunction with aspirin, acetaminophen, and caffeine. It was used in later formulations of Vincent's powders in Australia as a substitute for phenacetin.