Compound: 2'-DEOXYURIDINE
SMILES: O=c1n(ccc([nH]1)=O)[C@@H]2O[C@H](CO)[C@H](C2)O
InChIKey: MXHRCPNRJAMMIM-SHYZEUOFSA-N
Synonyms: 2'-DEOXYURIDINE, 951-78-0, deoxyuridine, Uracil deoxyriboside, 2-Deoxyuridine, dURD, Deoxyribose uracil, 2'-Desoxyuridine, Uridine, 2'-deoxy-, W78I7AY22C, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)uracil, 1-(2-Deoxy-beta-D-erythro-pentofuranoxyl)uracil, CHEBI:16450, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-ribofuranosyl)-, DTXSID30883621, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-ribofuranosyl)-, NSC-23615, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidine-2,4-dione, 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione, (beta 1-(2-Deoxyribopyranosyl))thymidine, RefChem:132010, 1-(4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidine-2,4-dione, DTXCID601023132, 213-455-7, 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, MFCD00006527, 2'-Deoxyuridine-1'-d, CCRIS 2832, NSC 23615, Desoxyuridine, Uracil desoxyuridine, 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, 1-[(4S,2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dihydropyrimidine-2, 4-dione, 1-(2-Deoxy-beta-D-ribofuranosyl)uracil, DUR, dU, 2'-dU, EINECS 213-455-7, BRN 0024433, UNII-W78I7AY22C, Uracildesoxyribosid, 2'-Deoxy-D-uridine, Adenosine Impurity 21, Uridinie, 2'-deoxy-, 2 inverted exclamation mark -Deoxyuridine, 2yb0, DEOXYURIDINE [MI], bmse000320, 2'-Deoxyuridine(2'-dU), SCHEMBL28844, MLS001066344, CHEMBL353955, orb1307628, SCHEMBL3878189, SCHEMBL4302151, 2 inverted exclamation marka-dU, SCHEMBL10577633, SCHEMBL27573408, 2'-Deoxyuridine, >=98.5%, MSK6807, BDBM777383, HMS2267D16, HY-D0186, US12441708, Example 37, s5505, ZINC00155696, AKOS015833069, AKOS015896792, 1-(2-Deoxy-ss-D-ribofuranosyl)uracil, CCG-247504, CS-W019820, DB02256, EBC-253274, ND06282, PS-7750, 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-furan-2-yl)pyrimidine-2,4(1H,3H)-dione, 1-(2-Deoxy-?-D-ribofuranosyl)-uracil, NCGC00142492-01, US20250313547, Example 37, BP-58660, DA-49411, SMR000112296, ST057093, SY038939, 1-(2-Deoxy-D-erythro-pentofuranosyl)uracil, D0060, NS00014663, 1-(2-Deoxy-delta-erythro-pentofuranosyl)uracil, C00526, O10766, EN300-7374520, F093489, Q419140, Q-200273, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)URACIL, E73B1553-A13A-4989-B045-A589A8F2B9DC, 1-(2-deoxy-beta-D-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-delta-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-delta-erythro-pentofuranosyl)-2,4(1H,3H)-Pyrimidinedione, 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1-H-pyrimidine-2,4-dione, 4-hydroxy-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Theoretical properties:
molecular_formula: C9H12N2O5
molecular_weight: 228.20 g/mol
exact_mass: 228.07462149 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 3
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 2
heavy_atom_count: 16
topological_polar_surface_area: 99.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside having uracil as the nucleobase. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to a uracil.
chebi: A pyrimidine 2'-deoxyribonucleoside having uracil as the nucleobase.
chembl: DEOXYURIDINE is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Floxuridine (also 5-fluorodeoxyuridine) is an oncology drug that belongs to the class known as antimetabolites. Specifically, floxuridine is a pyrimidine analog, classified as a deoxyuridine. The drug is usually administered via an artery, and most often used in the treatment of colorectal cancer. The quality of life and survival rates of individuals that receive continuous hepatic artery infusion of floxuridine for colorectal cancer metastases is significantly higher than control groups. Floxuridine can also be prescribed for the treatment of kidney and stomach cancers. In vitro uses of floxuridine include 5-minute treatments of fluorouracil, floxuridine, and mitomycin to increase cell proliferation in Tenon's capsule fibroblasts.