Compound: (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octane
SMILES: N1([C@@H]2CCC[C@H]1CC2)C
InChIKey: XLRPYZSEQKXZAA-OCAPTIKFSA-N
Synonyms: (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octane, 1alphaH,5alphaH-Tropane, 2,3-Dihydro-8-methylnortropidine, UNII-62QFG0728A, 62QFG0728A, TROPANE [MI], N-Methyl-8-azabicyclo[3.2.1]octane, 8-Azabicyclo(3.2.1)octane, 8-methyl-, CHEBI:35615, 1.ALPHA.H,5.ALPHA.H-TROPANE, N-METHYL-8-AZABICYCLO(3.2.1)OCTANE, (1R,5S)-8-methyl-8-azabicyclo(3.2.1)octane, DTXSID50879243, RefChem:192250, DTXCID101017257, 628-350-5, 529-17-9, 8-METHYL-8-AZABICYCLO(3.2.1)OCTANE, tropane, Tropane, 98%, SCHEMBL44881, SCHEMBL3242641, SCHEMBL14965708, XLRPYZSEQKXZAA-OCAPTIKFSA-N, 8-Azabicyclo[3.2.1]octane, 8-methyl-,?(1R,5S)-
Theoretical properties:
molecular_formula: C8H15N
molecular_weight: 125.21 g/mol
exact_mass: 125.120449483 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 0
heavy_atom_count: 9
topological_polar_surface_area: 3.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
{"pubchem": "Tropane is an alkaloid fundamental parent, a tropane alkaloid, an azabicycloalkane and a saturated organic heterobicyclic parent.", "chebi": null, "chembl": null, "wikipedia": "Cocaine is a stimulant of the central nervous system and tropane alkaloid, derived primarily from the leaves of two coca species native to South America: Erythroxylum coca and E. novogranatense. The leaves are processed into cocaine paste, a crude mixture of coca alkaloids, from which cocaine base is isolated and then converted to cocaine hydrochloride. Although total synthesis is possible, it is complex and not used for production. Historically, cocaine was a standard topical medication used as a local anesthetic with intrinsic vasoconstrictor properties. However, its high abuse potential, adverse effects, and cost have limited its medical use and led to its replacement by alternative medicines.\nStreet cocaine is commonly snorted, injected, or smoked as crack cocaine; its effects last up to 90 minutes depending on the route of administration. Pharmacologically, cocaine acts as a serotonin\u2013norepinephrine\u2013dopamine reuptake inhibitor (SNDRI), producing reinforcing effects such as euphoria, increased alertness, concentration, libido, and reduced fatigue and appetite.\nCocaine has numerous adverse effects. Acute use can cause vasoconstriction, tachycardia, hypertension, hyperthermia, or seizures, while overdose may lead to stroke, heart attack, or sudden cardiac death. It also produces a spectrum of psychiatric symptoms, including agitation, paranoia, anxiety, irritability, psychosis, hallucinations, delusions, violence, and suicidal or homicidal thinking. Prenatal exposure poses risks to fetal development. Chronic use may result in cocaine dependence, withdrawal symptoms, neurotoxicity, and nasal damage, including cocaine-induced midline destructive lesions.\nCoca cultivation and initial processing occur primarily in Latin America, especially in the Andes regions of Bolivia, Peru, and Colombia. Cultivation is expanding into Central America, including Honduras, Guatemala, and Belize. Violence linked to the cocaine trade continues to affect Latin America and the Caribbean and is expanding into Western Europe, Asia, and Africa as transnational organized crime groups compete globally. Cocaine remains the world's fastest-growing illicit drug market.\nCoca chewing dates back at least 8,000 years in South America. Large-scale cultivation occurred in Taiwan and Java prior to World War II. The cocaine boom\u2014a sharp rise in illegal production and trade\u2014began in the late 1970s and peaked in the 1980s. Cocaine is regulated under international drug control conventions, though its legal status varies nationally: several countries have decriminalized possession of small quantities."}