Compound: Isatin
SMILES: O=C1Nc2ccccc2C1=O
InChIKey: JXDYKVIHCLTXOP-UHFFFAOYSA-N
Synonyms: Isatin, 91-56-5, 1H-Indole-2,3-dione, INDOLE-2,3-DIONE, 2,3-Diketoindoline, 2,3-Dioxoindoline, Pseudoisatin, Isatic acid lactam, Isotin, Isatinic acid anhydride, o-Aminobenzoylformic anhydride, 2,3-Dioxo-2,3-dihydroindole, 2,3-dihydro-1H-indole-2,3-dione, DTXSID3038694, NSC-9262, 82X95S7M06, DTXCID1018694, CHEBI:27539, 2,3 Dioxoindoline, RefChem:148910, Indoline-2,3-dione, 2,3-Indolinedione, Isatine, Tribulin, 2,3-Ketoindoline, MFCD00005718, NSC 9262, 84788-92-1, 2,3-dihydroindole-2,3-dione, CHEMBL326294, 1H-benzo[d]azoline-2,3-dione, 1186480-61-4, EINECS 202-077-8, BRN 0383659, AI3-03111, 3-Indolinedione, UNII-82X95S7M06, indol-2, Indole-2, hydroxy-3-indolone, Isatin, p.a., 3-hydroxy-2-indolone, Isatin (Compound 1), Isatin, technical grade, 2H-indole-2,3-dione, ISATIN [MI], EC 202-077-8, WLN: T56 BMVVJ, SCHEMBL34016, 5-21-10-00221 (Beilstein Handbook Reference), MLS001066355, orb1300398, SCHEMBL1386281, SCHEMBL1501860, SCHEMBL1501879, SCHEMBL1809708, SCHEMBL7073534, SCHEMBL9027945, SCHEMBL28614049, SCHEMBL31087266, 2,3-Dihydro-indole-2,3-dione, BDBM11022, NSC9262, HMS2267D18, HMS3885P18, HMS5083G20, HMS6018N07, S00335a, HY-Y0265, 2,3-dihydro-1H-indol-2,3-dione, Tox21_202876, EBC-13637, s4717, SBB009100, STK387523, AKOS000119125, CCG-266182, CS-W020128, DB02095, FI02371, SB64041, CAS-91-56-5, NCGC00246983-01, NCGC00260422-01, AC-10666, AS-10908, SMR000471835, SY005277, DB-061345, I0080, NS00005535, ST50213409, EN300-17956, D70304, I-7801, F077309, Q421348, doi:10.14272/JXDYKVIHCLTXOP-UHFFFAOYSA-N.1, F9995-1662, Isatin, for spectrophotometric det. of proline and thiophene, >=99.0%, InChI=1/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11
Theoretical properties:
molecular_formula: C8H5NO2
molecular_weight: 147.13 g/mol
exact_mass: 147.032028402 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 0
heavy_atom_count: 11
topological_polar_surface_area: 46.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
vapor_pressure: 0.0000111 [mmHg]
Descriptions:
pubchem: Isatin is an indoledione that is the 2,3-diketo derivative of indole. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and a plant metabolite.
chebi: An indoledione that is the 2,3-diketo derivative of indole.
chembl: ISATIN is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Isatin, also known as tribulin, is an organic compound derived from indole with formula C8H5NO2. The compound was first obtained by Otto Linné Erdman  and Auguste Laurent  in 1840 as a product from the oxidation of indigo dye by nitric acid and chromic acids.
Isatin is a well-known natural product which can be found in plants of the genus Isatis, in Couroupita guianensis, and also in humans, as a metabolic derivative of adrenaline. 
It looks like a red-orange powder, and it is usually employed as building block for the synthesis of a wide variety of biologically active compounds including antitumorals,  antivirals,  anti-HIVs,  and antituberculars. 
The isatin core is also responsible for the color of "Maya blue" and "Maya yellow" dyes. 
Studies in rats indicate that isatin modulates neurotransmitter activity, antagonizes atrial natriuretic peptide and inhibits monoamine oxidase.