Compound: antazoline
SMILES: N1=C(NCC1)CN(c2ccccc2)Cc3ccccc3
InChIKey: REYFJDPCWQRWAA-UHFFFAOYSA-N
Synonyms: antazoline, 91-75-8, Phenazoline, Antihistal, Antastan, Antasten, Antistine, Histostab, Imidamine, Azalone, Antazolin, Antazolina, Ben-A-hist, Antazolinum, N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline, 2-(N-Phenyl-N-benzylaminomethyl)imidazoline, Antazolinum [Latin], Atazoline, 2-(N-Benzylanilinomethyl)-2-imidazoline, 5512-M, 2-Phenyl-benzyl-amino-methylimidazolin, 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine, 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, DHA8014SS1, DTXSID3022613, CHEBI:84115, Antazolinum (Latin), Antaz sulf, RefChem:112958, DTXCID902613, R01AC04, R06AX05, 202-094-0, Antistin, Phenazolin, N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline, Antazoline (INN), Imidamin, N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline hydrochloride, Analergine, N-Benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline, Antazolina [Spanish], ANTAZOLINE [INN], 2-[(N-Benzylanilino)methyl]-2-imidazoline, N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-N-(phenylmethyl)aniline, 2-Imidazoline, 2-((N-benzylanilino)methyl)-, 2-Imidazoline, 2-[(N-benzylanilino)methyl]-, Antazoline [INN:BAN], Antazolinum [INN-Latin], Antazolina [INN-Spanish], benzyl(4,5-dihydro-1H-imidazol-2-ylmethyl)phenylamine hydrochloride, Benzyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl-amine  . HCl, 2-Imidazoline, 2-(N-benzylanilinomethyl)-, HSDB 6506, 2-((N-BENZYLANILINO)METHYL)-2-IMIDAZOLINE, NCGC00016613-01, EINECS 202-094-0, 2-Phenyl-benzyl-amino-methylimidazolin [German], CAS-2508-72-7, BRN 0233924, UNII-DHA8014SS1, 91-75-8 (free base), Allergan A, Antazoline (Standard), Spectrum_000789, Tocris-0791, ANTAZOLINE [MI], Prestwick0_000258, Prestwick1_000258, Prestwick2_000258, Prestwick3_000258, Spectrum2_001259, Spectrum3_000303, Spectrum4_000141, Spectrum5_000818, ANTAZOLINE [HSDB], ANTAZOLINE [VANDF], ANTAZOLINE [MART.], SCHEMBL9437, ANTAZOLINE [WHO-DD], CHEMBL1305, BSPBio_000076, BSPBio_001866, KBioGR_000582, KBioSS_001269, 5-25-09-00364 (Beilstein Handbook Reference), cid_17275, DivK1c_000083, SPBio_001198, SPBio_002295, BPBio1_000084, GTPL7116, HY-B1067AR, orb1299787, orb1310946, orb3025916, BDBM76862, HY-B1067A, KBio1_000083, KBio2_001269, KBio2_003837, KBio2_006405, KBio3_001366, NINDS_000083, HMS3604F14, ALBB-023210, EBC-26375, s5946, AKOS015911230, CCG-213074, DB08799, FA30098, IDI1_000083, NCGC00016613-02, NCGC00016613-03, NCGC00016613-04, NCGC00016613-05, NCGC00016613-06, NCGC00016613-07, NCGC00016613-18, NCGC00023164-03, LS-14580, ST086981, (2-imidazolin-2-ylmethyl)phenylbenzylamine, SBI-0051285.P003, DB-050313, CS-0013323, NS00008002, D07458, G77641, AB00053420_19, AB00053420_20, EN300-6733612, L000841, Q771975, BRD-K99300445-001-01-2, BRD-K99300445-003-03-4, BRD-K99300445-003-20-8, BRD-K99300445-003-21-6, BRD-K99300445-011-02-9, BRD-K99300445-011-12-8, benzyl-(2-imidazolin-2-ylmethyl)-phenyl-amine;hydrochloride, N-Benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline #, benzyl-(2-imidazolin-2-ylmethyl)-phenyl-amine;phosphoric acid, Benzyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl-amine   HCl, N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-N-(phenylmethyl)aniline;hydrochloride
Theoretical properties:
molecular_formula: C17H19N3
molecular_weight: 265.35 g/mol
exact_mass: 265.157897619 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 5
heavy_atom_count: 20
topological_polar_surface_area: 27.6 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: White, crystalline powder
color: White, crystalline powder
odor: Odorless
melting_point: 227-229
Descriptions:
pubchem: Antazoline is a member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug. It has a role as a xenobiotic, a H1-receptor antagonist and a cholinergic antagonist. It is an aromatic amine, a tertiary amino compound and a member of imidazolines.
chebi: A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.
chembl: ANTAZOLINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Antazoline is a 1st generation antihistamine with anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis. To treat allergic conjunctivitis, antazoline can be combined in a solution with tetryzoline. The drug is a Histamine H1 receptor antagonist: selectively binding to but not activating the receptor, thereby blocking the actions of endogenous histamine and subsequently leading to the temporary relief of the negative symptoms brought on by histamine.