Compound: 2-Acetamidofluorene
SMILES: O=C(Nc1cc2c(-c3ccccc3C2)cc1)C
InChIKey: CZIHNRWJTSTCEX-UHFFFAOYSA-N
Synonyms: 2-Acetamidofluorene, 53-96-3, N-(9H-Fluoren-2-yl)acetamide, 2-Acetylaminofluorene, N-2-Fluorenylacetamide, 2-AAF, N-acetyl-2-aminofluorene, Acetamide, N-9H-fluoren-2-yl-, 2-FAA, 2-(Acetylamino)fluorene, 2-Acetaminofluorene, 2-Fluorenylacetamide, 2-Acetoaminofluorene, N-9H-Fluoren-2-ylacetamide, Acetoaminofluorene, Azetylaminofluoren, 2-Acetylamino-fluoren, ACETYLAMINOFLUORENE, RCRA waste number U005, Acetamide, N-fluoren-2-yl-, Fluorene, 2-acetamido-, DTXSID0039227, 9M98QLJ2DL, NSC-12279, DTXCID7018, CHEBI:17356, NSC12279, 2 Acetylaminofluorene, Aminofluorene AAF, AAF, aminofluorene, 2 Acetamidofluorene, 2 Fluorenylacetamide, Fluoren 2 ylacetamide, Fluoren-2-ylacetamide, N 2 Fluorenylacetamide, N Acetyl 2 Aminofluorene, RefChem:84993, 2AAF, 200-188-6, N-Fluoren-2-ylacetamide, N-(2-Fluorenyl)acetamide, NSC 12279, 2-ACETYLAMINOFLUORENE-3-YL, MFCD00001116, AAF, 2-Acetylaminfluorene, 2-Aminoacetylfluorene, 2-Fluorenil acetamide, CCRIS 1, Azetylaminofluoren [German], 2-Acetylamino-fluoren [German], HSDB 4077, Acetylaminofluorene, 2-, EINECS 200-188-6, RCRA waste no. U005, UNII-9M98QLJ2DL, BRN 2807677, AI3-52433, 2-Acetamidofluoren, C15-H13-N-O, 2-acetylaminoflourene, 2-Acetylaminofluorine, Oprea1_431359, SCHEMBL75140, CHEMBL311469, orb1689736, orb3026077, SCHEMBL3882856, SCHEMBL29364009, SCHEMBL29829339, GLXC-25238, WLN: L B656 HHJ EMV1, N-2-FLUORENYLACETAMIDE [MI], Tox21_200830, 2-ACETYLAMINOFLUORENE [HSDB], EBC-03740, MSK001828, SBB056657, STK386197, AKOS004006242, CCG-231696, CS-W014230, FA66753, HY-W013514, SB67003, CAS-53-96-3, MSK001828-1000A, NCGC00188968-01, NCGC00188968-02, NCGC00258384-01, AFF, BS-16973, SY067497, DB-020315, A0076, N-(2-Fluorenyl)acetamide, >=98% (HPLC), NS00006314, ST50308153, C02778, D82114, EN300-7478010, SR-01000394055, Q4382200, SR-01000394055-1, BRD-K63993117-001-01-3, Z29958697, 2-Acetamidofluorene Solution in Acetonitrile, 1000ug/mL, InChI=1/C15H13NO/c1-10(17)16-13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9H,8H2,1H3,(H,16,17
Theoretical properties:
molecular_formula: C15H13NO
molecular_weight: 223.27 g/mol
exact_mass: 223.099714038 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 1
heavy_atom_count: 17
topological_polar_surface_area: 29.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Crystals from alcohol + water
color: Crystals from alcohol + water
melting_point: 381 °F (NTP, 1992)
solubility: less than 1 mg/mL at 68.9 °F (NTP, 1992)
vapor_pressure: 0.00023 mmHg at 212 °F (NTP, 1992)
Descriptions:
pubchem: 2-Acetylaminofluorene can cause cancer according to an independent committee of scientific and health experts.
chebi: The parent of the class of 2-acetamidofluorenes, being an <em>ortho</em>-fused polycyclic arene that consists of 9<em>H</em>-fluorene bearing an acetamido substituent at position 2. It is a carcinogenic and mutagenic derivative of fluorene.
chembl: 2-ACETYLAMINOFLUORENE is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: N-hydroxy-2-acetamidofluorene reductase (EC 1.7.1.12) is an enzyme that catalyzes the chemical reaction

The three substrates of this enzyme are hydroxyacetylaminofluorene, reduced nicotinamide adenine dinucleotide (NADH), and a proton. Its products are 2-acetylaminofluorene, oxidised NAD+, and water. The enzyme can use nicotinamide adenine dinucleotide phosphate as an alternative cofactor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor.  The systematic name of this enzyme class is 2-acetamidofluorene:NAD(P)+ oxidoreductase. Other names in common use include N-hydroxy-2-acetylaminofluorene reductase, and NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase.