Compound: nafronyl
SMILES: O=C(OCCN(CC)CC)C(Cc1c2c(ccc1)cccc2)CC3OCCC3
InChIKey: KBAFPSLPKGSANY-UHFFFAOYSA-N
Synonyms: nafronyl, Naftidrofuryl, 31329-57-4, Naphtidrofuryl, Tridus, Dubimax, Gevatran, Naftidrofurilo, Naftidrofurylum, Drosunal, 42H8PQ0NMJ, 3-(1-Naphthyl)-2-tetrahydrofurfurylpropionic acid 2-(diethylamino)ethyl ester, 2-(diethylamino)ethyl 2-(naphthalen-1-ylmethyl)-3-(oxolan-2-yl)propanoate, Tetrahydro-alpha-(1-naphthalenylmethyl)-2-furanpropanoic acid 2-(diethylamino)ethyl ester, DTXSID3023344, 2-(Diethylamino)ethyl tetrahydro-alpha-(1-naphthylmethyl)-2-furanpropionate, naftidrofurile, Naftifurin Oxalate, 2-FURANPROPANOIC ACID, TETRAHYDRO-A-(1-NAPHTHALENYLMETHYL)-, 2-(DIETHYLAMINO)ETHYL ESTER, Naftiratiopharm, Nafti ratiopharm, Nafti Puren, Di Actane, Oxalate, Nafronyl, Oxalate, Naftifurin, RefChem:164412, DTXCID703344, C04AX21, LS121, 2-(diethylamino)ethyl 3-(naphthalen-1-yl)-2-(oxolan-2-ylmethyl)propanoate, 250-572-2, LS 84, 2-(Diethylamino)ethyl 3-(naphthalen-1-yl)-2-((tetrahydrofuran-2-yl)methyl)propanoate, C24H33NO3, Praxilene, 2-(diethylamino)ethyl 3-(naphthalen-1-yl)-2-[(oxolan-2-yl)methyl]propanoate, 2-Furanpropanoic acid, tetrahydro-alpha-(1-naphthalenylmethyl)-, 2-(diethylamino)ethyl ester, Naftidrofuryl (INN), NAFTIDROFURYL [INN], 2-Furanpropanoic acid, tetrahydro-.alpha.-(1-naphthalenylmethyl)-, 2-(diethylamino)ethyl ester, 2-Furanpropionic acid, tetrahydro-.alpha.-(1-naphthylmethyl)-, 2-(diethylamino)ethyl ester, Naftidrofuryl [INN:BAN], 2-(Diethylamino)ethyl tetrahydro-.alpha.-(1-naphthylmethyl)-2-furanpropionate, CHEMBL1439099, Tetrahydro-.alpha.-(1-naphthalenylmethyl)-2-furanpropanoic acid 2-(diethylamino)ethyl ester, Naftidrofurylum [INN-Latin], Naftidrofurilo [INN-Spanish], LS 121, NSC225233, EINECS 250-572-2, UNII-42H8PQ0NMJ, BRN 1296059, Oxalte, Drosunal (TN), Dubimax (Salt/Mix), Spectrum_001731, 2-(Diethylamino)ethyl tetrahydro-.alpha.-(1-naphthylmethyl)-2-furanpropionate oxalate (1:1), Nafronyl oxalate(USAN), NAFRONYL [MI], 2-Furanpropanoic acid, tetrahydro-.alpha.-(1-naphthalenylmethyl)-, 2-(diethylamino)ethyl ester, ethanedioate (1:1), Prestwick0_000377, Prestwick1_000377, Prestwick2_000377, Prestwick3_000377, Spectrum2_000868, Spectrum3_001598, Spectrum4_000855, Spectrum5_001127, GlyTouCan:G19707KM, N-Diethylaminoethyl beta-(1-naphthyl)-beta-tetrahydrofuryl isobutyrate, alpha-Tetrahydrofurfuryl-1-naphthalenepropionic acid 2-(diethylamino)ethyl ester, Tetrahydro-alpha-(1-naphthylmethyl)-2-furanpropanoic acid 2-(diethylamino)ethyl ester, SCHEMBL34062, BSPBio_000533, BSPBio_003196, KBioGR_001489, KBioSS_002211, DivK1c_000338, SPBio_000915, SPBio_002454, NAFTIDROFURYL [WHO-DD], BPBio1_000587, orb1701889, CHEMBL1620794, SCHEMBL29405813, CHEBI:91817, KBio1_000338, KBio2_002211, KBio2_004779, KBio2_007347, KBio3_002696, NINDS_000338, G19707KM, BDBM50347133, MFCD00868290, STL344054, 2-(Diethylamino)ethyl 3-(1-naphthyl)-2-(tetrahydro-2-furanylmethyl)propanoate, AKOS005068111, DB13588, FT26121, 2-Furanpropionic acid, tetrahydro-alpha-(1-naphthylmethyl)-, 2-(diethylamino)ethyl ester, IDI1_000338, NCGC00178213-01, NCGC00178213-02, NCGC00178213-04, SBI-0051824.P002, DB-048011, AB00053667, CS-0105327, NS00009221, D08244, AB00053667_10, EN300-7439215, Q425867, BRD-A67862938-034-05-7, BRD-A67862938-034-09-9, BRD-A67862938-034-14-9, 2-diethylaminoethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate, N-Diethylaminoethyl .beta.-(1-naphthyl)-.beta.-tetrahydrofuryl isobutyrate, .alpha.-Tetrahydrofurfuryl-1-naphthalenepropionic acid 2-(diethylamino)ethyl ester, 2-(1-naphthalenylmethyl)-3-(2-oxolanyl)propanoic acid 2-(diethylamino)ethyl ester, 2-(diethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate, 2-(Diethylamino)ethyl 2-[(naphthalen-1-yl)methyl]-3-(oxolan-2-yl)propanoate, 2-(Diethylamino)ethyl 3-(1-naphthyl)-2-(tetrahydro-2-furanylmethyl)propanoate oxalate, 2-(diethylamino)ethyl 3-(naphthalen-1-yl)-2-(tetrahydrofuran-2-ylmethyl)propanoate, 2-(diethylamino)ethyl 3-naphthalen-1-yl-2-(tetrahydrofuran-2-ylmethyl)propanoate, 2-(Diethylamino)ethyl ester tetrahydro-.alpha.-(1-naphthalenylmethyl)-2-furanpropanic acid, 2-(Diethylamino)ethyl tetrahydro-.alpha.-(1-naphthylmethyl)-2-furanpropionate ester, Tetrahydro-.alpha.-(1-naphthylmethyl)-2-furanpropanoic acid 2-(diethylamino)ethyl ester, Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic Acid 2-(Diethylamino)ethyl Ester, 2-Furanpropionic acid, tetrahydro-.alpha.-(1-naphthylmethyl)-, 2-(diethylamino)ethyl esteroxalate (1:1), TETRAHYDRO-.ALPHA.-(1-NAPHTHYLMETHYL)-2-FURANPROPIONIC ACID 2-(DIETHYLAMINO)ETHYL ESTER
Theoretical properties:
molecular_formula: C24H33NO3
molecular_weight: 383.5 g/mol
exact_mass: 383.24604391 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 11
heavy_atom_count: 28
topological_polar_surface_area: 38.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 2-(1-naphthalenylmethyl)-3-(2-oxolanyl)propanoic acid 2-(diethylamino)ethyl ester is a member of naphthalenes.
chembl: NAFRONYL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Naftidrofuryl, also known as nafronyl and sold under the brand name Praxilene among others, is a serotonin 5-HT2 receptor antagonist which is used as a vasodilator in the treatment of peripheral and cerebral vascular disorders. It is taken orally.