Compound: ethotoin
SMILES: O=C1N(C(=O)C(N1)c2ccccc2)CC
InChIKey: SZQIFWWUIBRPBZ-UHFFFAOYSA-N
Synonyms: ethotoin, 86-35-1, Peganone, 3-Ethyl-5-phenylhydantoin, 3-ethyl-5-phenylimidazolidine-2,4-dione, Accenon, Ethotoine, Etotoina, Ethotoinum, 3-Ethyl-5-phenylimidazolidin-2,4-dione, 1-Ethyl-2,5-dioxo-4-phenylimidazolidine, 3-Ethyl-5-phenyl-2,4-imidazolidinedione, Hydantoin, 3-ethyl-5-phenyl-, 2,4-Imidazolidinedione, 3-ethyl-5-phenyl-, (+-)-3-Ethyl-5-phenylhydantoin, NSC-760074, 46QG38NC4U, DTXSID6023020, 3-ethyl-5-phenyl-imidazolidine-2,4-dione, CHEBI:4888, DTXCID903020, 1-ethyl-2-hydroxy-4-phenyl-4,5-dihydro-1H-imidazol-5-one, RefChem:56515, N03AB01, 201-665-1, Ethotoine [INN-French], Ethotoinum [INN-Latin], Etotoina [INN-Spanish], AC-695; Accenon, MFCD00072127, (+/-)-3-ethyl-5-phenylhydantoin, Pegoanone, Peganone (TN), Accenon (TN), HSDB 3580, EINECS 201-665-1, Ethotoin (JAN/USP/INN), BRN 0188272, UNII-46QG38NC4U, Ethotoin [USP:INN:BAN:JAN], CAS-86-35-1, NCGC00016340-01, Ethotoin (Standard), ETHOTOIN [HSDB], ETHOTOIN [INN], ETHOTOIN [JAN], ETHOTOIN [MI], ETHOTOIN [VANDF], (.+/-.)-Ethotoin, Prestwick0_000696, Prestwick1_000696, Prestwick2_000696, Prestwick3_000696, ETHOTOIN [MART.], ETHOTOIN [USP-RS], ETHOTOIN [WHO-DD], CHEMBL1095, Oprea1_374844, SCHEMBL34301, BSPBio_000851, 5-24-08-00005 (Beilstein Handbook Reference), MLS002153961, SPBio_002772, ETHOTOIN [ORANGE BOOK], 2,4-Imidazolidinedione, 3-ethyl-5-phenyl-, (+-)-, BPBio1_000937, GTPL7183, orb1745261, ETHOTOIN [USP MONOGRAPH], HY-B1642R, HMS1570K13, HMS2097K13, HMS2232M06, HMS3371O03, HMS3714K13, HMS3887I05, HMS5086J05, Pharmakon1600-01505428, AAA08635, HY-B1642, Tox21_110383, EBC-14348, NSC760074, AKOS008947805, CCG-213433, DB00754, NSC 760074, NCGC00179401-01, NCGC00179401-03, DA-53024, NS-02146, SMR001233300, 3-Ethyl-5-phenyl-2,4-imidazolidinedione #, AB00513897, CS-0013593, NS00039122, C07839, D00708, EN300-938193, F88162, AB00513897_07, SR-01000841832, Q4533122, SR-01000841832-2, BRD-A30205217-001-11-2, BRD-A30205217-001-12-0, Z53845223, 2,4-IMIDAZOLIDINEDIONE, 3-ETHYL-5-PHENYL-, (+/-)-
Theoretical properties:
molecular_formula: C11H12N2O2
molecular_weight: 204.22 g/mol
exact_mass: 204.089877630 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 2
heavy_atom_count: 15
topological_polar_surface_area: 49.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Stout prisms from water.
color: Stout prisms from water.
Descriptions:
pubchem: Ethotoin is an imidazolidine-2,4-dione that is hydantoin substituted by ethyl and phenyl at positions 3 and 5, respectively. An antiepileptic, it is less toxic than phenytoin but also less effective. It has a role as an anticonvulsant.
chebi: An imidazolidine-2,4-dione that is hydantoin substituted by ethyl and phenyl at positions 3 and 5, respectively. An antiepileptic, it is less toxic than phenytoin but also less effective.
chembl: ETHOTOIN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Ethotoin (previously marketed as Peganone) is an anticonvulsant drug used in the treatment of epilepsy. It is a hydantoin, similar to phenytoin. It is not available in the United States.