Compound: hexamethonium
SMILES: [N+](CCCCCC[N+](C)(C)C)(C)(C)C
InChIKey: VZJFGSRCJCXDSG-UHFFFAOYSA-N
Synonyms: hexamethonium, Hexanium, Hexonium, 60-26-4, hexamethone, hexathonide, Hexamethonum, Hexamethonium ion, Hexamethonium cation, 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, 3C9PSP36Z2, Hexane-1,6-bis(trimethylammonium), Bitartrate, Hexamethonium, Ammonium, hexamethylenebis(trimethyl-, trimethyl[6-(trimethylazaniumyl)hexyl]azanium, trimethyl(6-(trimethylazaniumyl)hexyl)azanium, trimethyl-(6-(trimethylammonio)hexyl)ammonium, trimethyl-[6-(trimethylammonio)hexyl]ammonium, Iodide, Hexamethonium, Diiodide, Hexamethonium, Dibromide, Hexamethonium, RefChem:146065, Dihydroxide, Hexamethonium, Monotartrate, Hexamethonium, Diperchlorate, Hexamethonium, Dimethylsulfate, Hexamethonium, Dibromide Dihydrate, Hexamethonium, Dihydrate, Hexamethonium Dibromide, Dichloride Dihydrate, Hexamethonium, Dihydrate, Hexamethonium Dichloride, Bistrium, CHEMBL100622, trimethyl-[6-(trimethylazaniumyl)hexyl]azanium, DTXSID9045053, N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium, NCGC00163239-01, DTXCID7025053, Esametonio, CHEMBL332524, CAS-60-26-4, Esametonio [Italian], Hexamethonium [INN], UNII-3C9PSP36Z2, hexamethylenebis(trimethylammonium), Hexamethoniumdibromide, BRN 1760389, Spectrum_001659, Prestwick0_000038, Prestwick1_000038, Prestwick2_000038, Prestwick3_000038, Spectrum2_001552, Spectrum3_000964, Spectrum4_001081, Spectrum5_001213, Lopac-H-0879, Lopac-H-2138, HEXAMETHONIUM [MI], Lopac0_000613, Lopac0_000622, SCHEMBL34900, BSPBio_000135, BSPBio_002567, KBioGR_001462, KBioSS_002139, DivK1c_000663, SPBio_001424, SPBio_002056, HEXAMETHONIUM [WHO-DD], BPBio1_000149, CHEBI:5700, GTPL3963, orb1740458, KBio1_000663, KBio2_002139, KBio2_004707, KBio2_007275, KBio3_001787, NINDS_000663, Tox21_112036, BDBM50038416, AKOS032954387, Tox21_112036_1, CCG-204702, DB08960, IDI1_000663, NCGC00015496-01, NCGC00015496-02, NCGC00015496-03, NCGC00015496-04, NCGC00015496-05, NCGC00015496-06, NCGC00015496-07, NCGC00015496-08, NCGC00015496-18, NCGC00015496-19, NCGC00162203-01, NCGC00162203-02, (1,6-trimethyl ammonium)hexane; dibromide, SBI-0050595.P004, AB00053821, NS00003785, C07510, AB00053821_08, AB00053821_09, Q410557, .ALPHA.,.OMEGA.-BIS(TRIMETHYLAMMONIUM)HEXANE, BRD-K10598093-303-05-3, BRD-K10598093-303-06-1, BRD-K10598093-303-07-9, N1,N1,N1,N6,N6,N6-hexamethylhexane-1,6-diaminium, N,N,N,N'''',N'''',N''''-Hexamethyl-1,6-hexanediaminium dibromide, N,N,N,N'''',N'''',N''''-Hexamethylhexane-1,6-diammoniumdibromide, N~1~,N~1~,N~1~,N~6~,N~6~,N~6~-Hexamethylhexane-1,6-bis(aminium), N(SUP 1),N(SUP 1),N(SUP 1),N(SUP 6),N(SUP 6),N(SUP 6)-HEXAMETHYL-1,6-HEXANEDIAMINIUM
Theoretical properties:
molecular_formula: C12H30N2+2
molecular_weight: 202.38 g/mol
exact_mass: 202.240898965 g/mol
formal_charge: 2
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 0
rotatable_bond_count: 7
heavy_atom_count: 14
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 290-291
Descriptions:
pubchem: Hexamethonium is a quaternary ammonium salt.
chembl: HEXAMETHONIUM is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Hexamethonium is a non-depolarising ganglionic blocker, a neuronal nicotinic (nAChR) receptor antagonist   that acts in autonomic ganglia by binding mostly in or on the nAChR receptor, and not the acetylcholine binding site itself. It does not have any effect on the muscarinic acetylcholine receptors (mAChR) located on target organs of the parasympathetic nervous system, nor on the nicotinic receptors at the skeletal neuromuscular junction, but acts as antagonist at the nicotinic acetylcholine receptors located in sympathetic and parasympathetic ganglia (nAChR).