Compound: propafenone
SMILES: O=C(c1c(OCC(O)CNCCC)cccc1)CCc2ccccc2
InChIKey: JWHAUXFOSRPERK-UHFFFAOYSA-N
Synonyms: propafenone, 54063-53-5, Propafenona, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one, Propafenonum, Propafenon Hexal, GNF-Pf-4594, 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one, 68IQX3T69U, DTXSID9045184, 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one, DTXCID7025184, CHEBI:63619, 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, 2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone, 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, Norfenon, Pintoform, Propafenon Minden, RefChem:55924, SA79, C01BC03, 258-955-6, Rythmol, Propafenonum [INN-Latin], Propafenona [INN-Spanish], Propafenone (INN), CHEMBL631, 1-[2-(2-hydroxy-3-propylamino-propoxy)phenyl]-3-phenyl-propan-1-one, MFCD00216020, Paraffin with ceresin, NCGC00015819-06, 1-(2-(2-Hydroxy-3-propylaminopropoxy)phenyl)-3-phenylpropan-1-one, PROPAFENONE [INN], 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-propan-1-one, Propafenone [INN:BAN], CAS-54063-53-5, EINECS 258-955-6, UNII-68IQX3T69U, Rhytmol, 1-[2-(2-hydroxy-3-propylaminopropoxy)phenyl]-3-phenylpropan-1-one, (R)-SA-79, (S)-SA-79, HSDB 7929, (+/-)-Propafenone, Propafenone (Standard), Spectrum_001612, PROPAFENONE [MI], Prestwick0_000499, Prestwick1_000499, Prestwick2_000499, Prestwick3_000499, Spectrum2_001603, Spectrum3_001905, Spectrum4_000209, Spectrum5_001271, GlyTouCan:G40724BB, C07381, PROPAFENONE [VANDF], Lopac0_000919, SCHEMBL27865, BSPBio_000397, BSPBio_001465, BSPBio_003470, KBioGR_000817, KBioSS_002092, PROPAFENONE [WHO-DD], DivK1c_000906, SPBio_001605, SPBio_002318, BPBio1_000437, GTPL2561, orb1310219, SCHEMBL16730120, BCBcMAP01_000079, HY-B0432R, KBio1_000906, KBio2_002092, KBio2_004660, KBio2_007228, KBio3_002974, NINDS_000906, HMS1791J07, HMS1989J07, HMS2089E09, HMS3259O16, HMS3402J07, HMS3656O08, HMS5081K13, HMS5087K05, G40724BB, HY-B0432, Tox21_110228, BDBM50067133, EBC-06046, MSK160272, s2500, s5789, STL284627, AKOS000276940, AKOS022106720, Tox21_110228_1, CCG-205001, DB01182, NC00582, SDCCGSBI-0050894.P004, IDI1_000906, NCGC00015819-04, NCGC00015819-05, NCGC00015819-07, NCGC00015819-08, NCGC00015819-10, NCGC00015819-11, NCGC00015819-15, NCGC00015819-24, NCGC00089784-02, NCGC00089784-03, NCGC00089784-04, NCGC00089784-05, AC-37643, SBI-0050894.P003, AB00053687, CS-0009325, NS00010400, SW196964-3, EN300-58332, D08435, G78087, AB00053687-14, AB00053687_15, AB00053687_16, Q662511, BRD-A26334849-001-02-1, BRD-A26334849-001-06-2, BRD-A26334849-003-05-0, BRD-A26334849-003-16-7, BRD-A26334849-003-23-3, 2'-[2-Hydroxy-3-(propylamino)propoxy]-3-phenylpropiophenone, 1-(2-[2-Hydroxy-3-(propylamino)propoxy]phenyl)-3-phenyl-1-propanone #, 1-[2-(2-Hydroxy-3-propylamino-propoxy)-phenyl]-3-phenyl-propan-1-one, 1-[2-(2-Hydroxy-3-propylamino-propoxy)-phenyl]-3-phenyl-propan-1-one (propafenone), 9083-41-4
Theoretical properties:
molecular_formula: C21H27NO3
molecular_weight: 341.4 g/mol
exact_mass: 341.19909372 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 11
heavy_atom_count: 25
topological_polar_surface_area: 58.6 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: Slightly soluble
Descriptions:
pubchem: Propafenone is an aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias. It has a role as an anti-arrhythmia drug. It is a secondary alcohol, a secondary amino compound and an aromatic ketone. It is a conjugate base of a propafenone(1+).
chebi: An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
chembl: PROPAFENONE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Propafenone, sold under the brand name Rythmol among others, is a class 1c anti-arrhythmic medication, which is used to treat illnesses associated with rapid heart beat such as atrial and ventricular arrhythmias.