Compound: kojic acid
SMILES: O=c1c(O)coc(c1)CO
InChIKey: BEJNERDRQOWKJM-UHFFFAOYSA-N
Synonyms: kojic acid, 501-30-4, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one, 5-Hydroxy-2-(hydroxymethyl)-4-pyrone, 5-hydroxy-2-(hydroxymethyl)pyran-4-one, 5-Hydroxy-2-hydroxymethyl-4-pyrone, 4H-PYRAN-4-ONE, 5-HYDROXY-2-(HYDROXYMETHYL)-, acido kojico, 2-Hydroxymethyl-5-hydroxy-gamma-pyrone, 2-(Hydroxymethyl)-5-hydroxy-4H-pyran-4-one, DTXSID2040236, CHEBI:43572, 6K23F1TT52, NSC-1942, DTXCID0020236, Beaute, Cleansing Pasds, TurmericKojicSoap, Surfree Kojic Acid, CLEANSING PADS, Kojic Acid Dark Spot, Kojic Acid 0.6%, Kojic Acid 4.4%, RefChem:5934, RET I NOL, Deodorant Underarms Body Skin, GZE Lemon Turmeric Kojic ScidSoap, Kojic Acid Turmeric Cleansing Pads, CVC TURMERIC CLEANSING PASDS, GZE Lemon Turmeric Kojic Acid LiquidSoap, Kambuta Turmeric Kojic acid Cleansing Pasds, 207-922-4, MFCD00006580, 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one, Pyran-4-one, 5-hydroxy-2-(hydroxymethyl), 123712-78-7, 5-Hydroxy-2-hydroxymethyl-pyran-4-one, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone, CHEMBL287556, NSC1942, NCGC00017325-03, NCGC00017325-06, CAS-501-30-4, CCRIS 4131, NSC 1942, EINECS 207-922-4, BRN 0120895, kojate, Kojisaeure, UNII-6K23F1TT52, AI3-02549, HSDB 7664, Kojic acid (Standard), Spectrum_000191, 2-HYDROXYMETHYL-5-HYDROXY-4-PYRONE, KOJIC ACID [MI], Spectrum2_001828, Spectrum3_001704, Spectrum4_000571, Spectrum5_001085, Natural Kojic Acid Powder, Epitope ID:613437, KOJIC ACID [HSDB], KOJIC ACID [IARC], KOJIC ACID [MART.], Oprea1_038773, SCHEMBL36895, BSPBio_003288, KBioGR_001002, KBioSS_000671, KOJIC ACID [WHO-DD], 5-18-02-00516 (Beilstein Handbook Reference), BIDD:ER0501, DivK1c_000923, SPBio_001875, Kojic acid, analytical standard, MEGxm0_000388, orb1301405, orb3139760, WLN: T6O DVJ B1Q EQ, SCHEMBL11610438, ACon1_000622, BEJNERDRQOWKJM-UHFFFAOYSA-, HMS502O05, KBio1_000923, KBio2_000671, KBio2_003239, KBio2_005807, KBio3_002508, NINDS_000923, GLXC-08094, HMS3604L04, HMS5084J11, KUC106760N, HY-W050154R, TNP00261, 2-Hydroxymethyl-5-hydroxy-?-pyrone, Tox21_110814, Tox21_113449, BBL010645, BDBM50031467, CCG-38458, EBC-03969, s5174, SBB005397, STK801688, AKOS000120649, Tox21_110814_1, 5-Hydroxy-2-hydroxymethyl-I(3)-pyron, DB01759, FK01303, HY-W050154, MSK000547-100W, IDI1_000923, SMP1_000171, MSK000547-1000W, NCGC00017325-01, NCGC00017325-02, NCGC00017325-04, NCGC00017325-05, NCGC00017325-10, NCGC00142361-01, NCGC00168903-01, NCGC00168903-02, NCGC00181145-01, AC-11658, AS-11648, Kojic acid Solution in Water, 100ug/mL, Kojic acid, purum, >=98.0% (HPLC), KSC-11-228-2, ST019399, SY018009, Kojic acid Solution in Water, 1000ug/mL, 2-Hydroxymethyl-5-hydroxy-4H-pyran-4-one, CS-0032701, K0010, K0012, NS00013805, EN300-20919, C91105, 2-HYDROXYMETHYL-5-HYDROXY-.GAMMA.-PYRONE, AN-584/40205787, F046837, Q416285, SR-01000945134, SR-01000945134-1, C65A72E0-0E46-4AF4-AA68-178ECA2E5FCC, F0001-1307, Z104484860, InChI=1/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
Theoretical properties:
molecular_formula: C6H6O4
molecular_weight: 142.11 g/mol
exact_mass: 142.02660867 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 1
heavy_atom_count: 10
topological_polar_surface_area: 66.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Prismatic needles from acetone, ethanol+ether or methanol+ethyl acetate
color: Prismatic needles from acetone, ethanol+ether or methanol+ethyl acetate
solubility: Soluble in ethanol, ethyl ether, acetone, DMSO; slightly soluble in benzene
Descriptions:
pubchem: Kojic acid is a pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae. It has a role as an EC 1.14.18.1 (tyrosinase) inhibitor, a NF-kappaB inhibitor, an Aspergillus metabolite, a skin lightening agent, an EC 1.10.3.1 (catechol oxidase) inhibitor, an EC 1.10.3.2 (laccase) inhibitor, an EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor and an EC 1.4.3.3 (D-amino-acid oxidase) inhibitor. It is a member of 4-pyranones, a primary alcohol and an enol. It derives from a hydride of a 4H-pyran.
chebi: A pyranone that is 4<em>H</em>-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus <em>Aspergillus oryzae</em>.
chembl: KOJIC ACID is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Kojic acid is an organic compound with the formula HOCH2C5H2O2OH. It is a derivative of 4-pyrone that functions in nature as a chelation agent produced by several species of fungus, especially Aspergillus oryzae, which has the Japanese common name koji. Kojic acid is a by-product in the fermentation process of malting rice, for use in the manufacturing of sake, the Japanese rice wine.  It is a mild inhibitor of the formation of pigment in plant and animal tissues, and is used in food and cosmetics to preserve or change colors of substances. It forms a bright red complex with ferric ions.