Compound: methylglyoxal
SMILES: O=C(C=O)C
InChIKey: AIJULSRZWUXGPQ-UHFFFAOYSA-N
Synonyms: methylglyoxal, 2-Oxopropanal, pyruvaldehyde, pyruvic aldehyde, 78-98-8, acetylformaldehyde, Acetylformyl, Propanal, 2-oxo-, 2-Ketopropionaldehyde, METHYL GLYOXAL, Propanedione, Propanolone, Pyroracemic aldehyde, 2-Oxopropionaldehyde, Glyoxal, methyl, 1-Ketopropionaldehyde, alpha-Ketopropionaldehyde, Acetalformaldehyde, FEMA No. 2969, acetyl formaldehyde, NSC 79019, DTXSID0021628, CHEBI:17158, NSC-79019, 722KLD7415, NSC-626580, DTXCID101628, NSC-337790, Aldehyde, Pyruvic, RefChem:389253, 201-164-8, Propionaldehyde, 2-keto, Propionaldehyde, 2-oxo-, 1,2-Propanedione, alpha-Ketopropionic aldehyde, CCRIS 1741, methyl-glyoxal, 2-oxo-propanal, .alpha.-Ketopropionaldehyde, NSC 626580, 2-oxo-Propionaldehyde, CH3COCHO, MFCD00006960, Pyruvaldehyde, 40% aqueous solution, NSC626580, oxopropanal, Pyruvaldehyde (35% w/w aqueous), 51252-84-7, EINECS 201-164-8, NSC 337790, BRN 0906750, pyruvicaldehyde, UNII-722KLD7415, HSDB 7510, Ketopropionaldehyde, Pyruvaldehyde (8CI), 2-keto Propionaldehyde, GlyTouCan:G09037VU, METHYLGLYOXAL [MI], Epitope ID:143620, WLN: VHV1, EC 201-164-8, METHYLGLYOXAL [IARC], PYRUVALDEHYDE [FHFI], SCHEMBL47032, 4-01-00-03631 (Beilstein Handbook Reference), Propanal, 2-oxo- (9CI), Pyruvic aldehyde Methylglyoxal, METHYL GLYOXAL [HSDB], Pyruvaldehyde, 40% in water, SCHEMBL442559, METHYLGLYOXAL [WHO-DD], CHEMBL170721, GTPL6303, orb1909192, SCHEMBL3026765, SCHEMBL6279758, MSK1667, Pyruvic Aldehyde (40% in water), G09037VU, NSC79019, STR03080, Tox21_303931, EBC-48026, NSC133492, NSC133493, Pyruvaldehyde, 35% aqueous solution, Pyruvaldehyde (40% in water, w/w), AKOS000119318, AB00820, DB03587, FP33211, HY-W020014, NSC-133492, NSC-133493, CAS-78-98-8, Pyruvaldehyde (35per cent w/w aqueous), NCGC00356972-01, BP-20618, Pyruvic aldehyde, 35-45% w/w aq. Soln, CS-0031856, NS00005494, EN300-21293, C00546, F069255, Q903881, 194597AC-5BFC-42EA-B6C8-DA2E5FAA13AF, F0001-2060, Z104495190, Pyruvic aldehyde - Technical grade, 35-45% w/w aqueous solution, Pyruvic aldehyde, 35-45% w/w aq. soln(Discontinued,See C4X-1720171)
Theoretical properties:
molecular_formula: C3H4O2
molecular_weight: 72.06 g/mol
exact_mass: 72.021129366 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 1
heavy_atom_count: 5
topological_polar_surface_area: 34.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Clear, yellow liquid
color: Clear, yellow liquid
odor: Pungent
boiling_point: 162 °F at 760 mmHg (NTP, 1992)
melting_point: < 25 °C
density: 1.06 at 68 °F (NTP, 1992) - Denser than water; will sink
solubility: greater than or equal to 100 mg/mL at 63 °F (NTP, 1992)
vapor_pressure: 26.7 [mmHg]
Descriptions:
pubchem: Methylglyoxal is a 2-oxo aldehyde derived from propanal. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a member of propanals and a 2-oxo aldehyde.
chebi: A 2-oxo aldehyde derived from propanal.
chembl: METHYLGLYOXAL is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Methylglyoxal (MGO) is the organic compound with the formula CH3C(O)CHO.  It is a reduced derivative of pyruvic acid.  It is a reactive compound that is implicated in the biology of diabetes.  Methylglyoxal is produced industrially by degradation of carbohydrates using overexpressed methylglyoxal synthase.