Compound: tripelennamine
SMILES: n1c(N(Cc2ccccc2)CCN(C)C)cccc1
InChIKey: UFLGIAIHIAPJJC-UHFFFAOYSA-N
Synonyms: tripelennamine, 91-81-6, Pyrinamine base, Tripelennamin, Benzoxale, Resistamine, Cizaron, Tonaril, Piribenzil, Tripelennamina, Pyribenzamin, Tripelenamina, Tripelennaminum, N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine, 1,2-Ethanediamine, N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-, 2-(Benzyl(2-dimethylaminoethyl)amino)pyridine, N-Benzyl-N',N'-dimethyl-N-2-pyridylethylenediamine, beta-Dimethylaminoethyl-2-pyridylbenzylamine, beta-Dimethylaminoethyl-2-pyridylaminotoluene, 3C5ORO99TY, NSC-118946, N,N-Dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-1,2-ethanediamine, Benzyl-(alpha-pyridyl)-dimethylaethylendiamin, 2-[Benzyl(2-dimethylaminoethyl)amino]pyridine, N,N-Dimethyl-N'-benzyl-N'-(alpha-pyridyl)ethylenediamine, Pyridine, 2-(benzyl(2-(dimethylamino)ethyl)amino)-, DTXSID8023717, Pyridine, 2-[benzyl[2-(dimethylamino)ethyl]amino]-, N-benzyl-N-(2-(dimethylamino)ethyl)pyridin-2-amine, PBZ OTC, Tripelennamine HCl 1%, RefChem:56177, DTXCID803717, D04AA04, R06AC04, 202-100-1, Tripelenamine, Tripelannamine, Tripelennamine [INN], Pyristine (piristina), N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine, NCI-C60662, N,N-Dimethyl-N'-benzyl-N'-(2-pyridyl)ethylenediamine, N-Benzyl-N-(2-pyridyl)-N',N'-dimethyl ethylenediamine, NSC 118946, Tripelennamine (INN), 2-(N-Benzyl-N-(2-dimethylaminoethyl)amino)pyridine, N-Benzyl-N',N'-dimethyl-N-(2-pyridyl)ethylenediamine, 2750 R.P., Ethylenediamine, N-benzyl-N',N'-dimethyl-N-(2-pyridyl)-, Benzyl-.alpha.-pyridyl-dimethyl-aethylendiamin, .beta.-Dimethylaminoethyl-2-pyridylaminotoluene, Ts and Blues, Pyridbenzamine, Tripellenamine, Triplennamine, N,N-Dimethyl-N'-benzyl-N'-(.alpha.-pyridyl)ethylenediamine, .beta.-Dimethylaminoethyl-2-pyridylbenzylamine, N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine;hydron;chloride, Tripelennamina [Italian], 2-[N-Benzyl-N-(2-dimethylaminoethyl)amino]pyridine, Tripelenamina [INN-Spanish], Tripelennaminum [INN-Latin], N-Benzyl-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine, HSDB 5191, EINECS 202-100-1, Tripelennamine [INN:BAN], UNII-3C5ORO99TY, BRN 0227074, Benzyl-(alpha-pyridyl)-dimethylaethylendiamin [German], ReCovr (Salt/Mix), Dehistin (Salt/Mix), Ahistamin (Salt/Mix), Spectrum_000141, Stanzamine (Salt/Mix), Tri-Tumine (Salt/Mix), Spectrum2_000957, Spectrum3_001696, Spectrum4_000374, Spectrum5_001581, TRIPELENNAMINE [MI], 2-(benzyl(2-(dimethylamino)ethyl)amino)pyridine, CHEMBL1241, Oprea1_266730, SCHEMBL17970, BSPBio_003252, KBioGR_000867, KBioSS_000621, TRIPELENNAMINE [HSDB], 5-22-08-00378 (Beilstein Handbook Reference), DivK1c_000534, TRIPELENNAMINE [VANDF], SPBio_000954, CHEBI:9741, GTPL7318, N-Benzyl-N',N'-dimethyl-N-2-(pyridylethylene)diamine, orb1689628, TRIPELENNAMINE [WHO-DD], SCHEMBL29600775, BDBM81471, KBio1_000534, KBio2_000621, KBio2_003189, KBio2_005757, KBio3_002472, NINDS_000534, AntiAllergicum Medivet (Salt/Mix), NSC_5587, WLN: T6NJ BN1R&2N1&1, 1,2-Ethanediamine,N1,N1-dimethyl-N2-(phenylmethyl)-N2-2-pyridinyl-, EBC-26341, HY-17428A, N,N-dimethyl-N'-(phenylmethyl)-N'-pyridin-2-ylethane-1,2-diamine, NSC118946, DB00792, FT65196, CAS_91-81-6, IDI1_000534, WLN: T6NJ BN1R&2N1&1 &GH, NCGC00018125-01, NCGC00018125-02, NCGC00018125-03, DA-78629, SBI-0051548.P002, CS-0009189, NS00003396, Benzyl-(.alpha.-pyridyl)-dimethylaethylendiamin, C07180, D08645, EN300-708778, Tripelennamine 1000 microg/mL in Acetonitrile, AB00053562_13, AB00053562_14, L000603, pyridine, 2-[benzyl(2-dimethylaminoethyl)amino]-, Q415203, 1, N,N-dimethyl-N'-(phenylmethyl)-N'-2-pyridinyl-, BRD-K57033106-003-19-7, BRD-K57033106-048-02-8, BRD-K57033106-048-03-6, BRD-K57033106-048-04-4, N'-benzyl-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine, N\'-benzyl-N,N-dimethyl-N\'-pyridin-2-ylethane-1,2-diamine, N~1~-Benzyl-N~2~,N~2~-dimethyl-N~1~-(pyridin-2-yl)ethane-1,2-diamine
Theoretical properties:
molecular_formula: C16H21N3
molecular_weight: 255.36 g/mol
exact_mass: 255.173547683 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 6
heavy_atom_count: 19
topological_polar_surface_area: 19.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: YELLOW OIL
color: YELLOW OIL
odor: AMINE ODOR
boiling_point: 365 to 374 °F at 1.7 mmHg (NTP, 1992)
solubility: Very soluble (NTP, 1992)
Descriptions:
pubchem: Tripelennamine is an aromatic amine.
chembl: TRIPELENNAMINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as it has been replaced by newer antihistamines. The drug was patented at CIBA, which merged with Geigy into Ciba-Geigy, and eventually becoming Novartis.