Compound: Kuwanon G
SMILES: O=c1c2c(oc(c1CC=C(C)C)-c3c(O)cc(O)cc3)c(c(O)cc2O)[C@H]4C=C(C[C@H]([C@@H]4C(=O)c5c(O)cc(O)cc5)c6c(O)cc(O)cc6)C
InChIKey: APPXYONGBIXGRO-AIQWNVMPSA-N
Synonyms: Kuwanon G, 75629-19-5, Kuwanone G, GQ6QVK8YZM, CHEBI:6146, DTXSID40226540, NSC-356888, 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-cyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one, 8-((1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-cyclohex-2-en-1-yl)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one, RefChem:924292, DTXCID70149031, moracenin b, KuwanonG, kumanon G, 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one, MFCD05662262, Kuwanon, 4H-1-Benzopyran-4-one, 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-, Kuwanon G (Standard), UNII-GQ6QVK8YZM, CHEMBL444942, orb1303383, SCHEMBL20211451, SCHEMBL29425236, SCHEMBL29998764, HY-N4247R, APPXYONGBIXGRO-AIQWNVMPSA-N, HY-N4247, BDBM50540963, MSK157267, AKOS030573630, EBC-616310, FK30428, NSC 356888, 8-[(1S,5R,6S)-6-(2,4-DIHYDROXYBENZOYL)-5-(2,4-DIHYDROXYPHENYL)-3-METHYLCYCLOHEX-2-EN-1-YL]-2-(2,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-3-(3-METHYLBUT-2-EN-1-YL)-4H-CHROMEN-4-ONE, 8-[(1S,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one, AC-34789, DA-54709, MS-31140, CS-0032528, Q15634181, 4H-1-Benzopyran-4-one, 8-(6-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-, (1S-(1alpha,5alpha,6beta))-, 4H-1-Benzopyran-4-one, 8-[(1S,5R,6S)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-buten-1-yl)-, 4H-1-Benzopyran-4-one, 8-[6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-, [1S-(1alpha,5alpha,6beta)]-, 8-((1R,2S,3S)-2-(2,4-dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-en-1-yl)-4H-chromen-4-one, 8-[(1R,2S,3S)-2-(2,4-Dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro[1,1'-biphenyl]-3-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-en-1-yl)-4H-1-benzopyran-4-one, 8-[(1R,2S,3S)-2-(2,4-dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl[1,2,3,6-tetrahydro[1,1'-biphenyl]]-3-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-en-1-yl)-4H-1-benzopyran-4-one, 8-[(1S,5R,6S)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
Theoretical properties:
molecular_formula: C40H36O11
molecular_weight: 692.7 g/mol
exact_mass: 692.22576196 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 8
hydrogen_bond_acceptor_count: 11
rotatable_bond_count: 7
heavy_atom_count: 51
topological_polar_surface_area: 205 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Kuwanone G is a tetrahydroxyflavone isolated from the root barks of Morus alba and has been shown to exhibit anti-inflammatory activity. It has a role as an anti-inflammatory agent and a plant metabolite. It is a member of resorcinols and a tetrahydroxyflavone.
chebi: A tetrahydroxyflavone isolated from the root barks of <em>Morus alba </em> and has been shown to exhibit anti-inflammatory activity.
chembl: KUMANON G is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Kuwanon G is an antimicrobial bombesin receptor antagonist isolated from white mulberry (Morus alba).