Compound: trimethobenzamide
SMILES: O=C(NCc1ccc(OCCN(C)C)cc1)c2cc(OC)c(OC)c(c2)OC
InChIKey: FEZBIKUBAYAZIU-UHFFFAOYSA-N
Synonyms: trimethobenzamide, 138-56-7, Trimetobenzamida, Trimethobenzamidum, Ametik damla, Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-, 4-(2-Dimethylaminoethoxy)-N-(3,4,5-trimethoxybenzoyl)benzylamine, W2X096QY97, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide, DTXSID8023711, CHEBI:27796, Benzamide, N-(p-(2-(dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxy-, N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide, Benzamide, N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4,5-trimethoxy-, N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide, trimetobenzamide, N-((4-(2-(dimethylamino)ethoxy)phenyl)methyl)-3,4,5-trimethoxybenzamide, N-((4-(2-dimethylaminoethoxy)phenyl)methyl)-3,4,5-trimethoxybenzamide, RefChem:56173, DTXCID403711, R06AA10, 205-332-1, N-(4-(2-(Dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxybenzamide, emedur, Trimethobenzamide [INN], Trimethobenzamidum [INN-Latin], Trimetobenzamida [INN-Spanish], Tribenzagan, Benzacot, Stemetic, Trimethobenzamide (INN), HSDB 3198, NCGC00016509-01, CAS-554-92-7, EINECS 205-332-1, UNII-W2X096QY97, N-(4-[2-(Dimethylamino)ethoxy]benzyl)-3,4,5-trimethoxybenzamide, N-{4-[2-(dimethylamino)ethoxy]benzyl}-3,4,5-trimethoxybenzamide, Ametik damla (TN), MFCD00599601, Spectrum_000117, N-((2-Dimethylaminoethoxy)benzyl)-3,4,5-trimethoxybenzamide, Prestwick0_000080, Prestwick1_000080, Prestwick2_000080, Prestwick3_000080, Spectrum2_000844, Spectrum3_001377, Spectrum4_000371, Spectrum5_000969, SCHEMBL28858, BSPBio_000299, BSPBio_002934, KBioGR_000861, KBioSS_000557, DivK1c_000425, TRIMETHOBENZAMIDE [MI], SPBio_000827, SPBio_002220, BPBio1_000329, GTPL7614, orb1691759, TRIMETHOBENZAMIDE [HSDB], CHEMBL1201256, KBio1_000425, KBio2_000557, KBio2_003125, KBio2_005693, KBio3_002154, TRIMETHOBENZAMIDE [VANDF], NINDS_000425, HMS3604F21, TRIMETHOBENZAMIDE [WHO-DD], N-[p-[2-(Dimethylamino)ethoxy]benzyl]-3,4,5-trimethoxybenzamide, EBC-13568, MSK178160, AKOS007167113, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-benzamide, DB00662, IDI1_000425, NCGC00016509-02, NCGC00016509-03, NCGC00016509-08, AS-76970, DA-58736, HY-12751, SBI-0051546.P002, AB00053561, CS-0012340, NS00010374, C07178, D08643, D94499, EN300-119183, AB00053561_08, Q7842199, BRD-K34415467-003-05-6, BRD-K34415467-003-08-0, BRD-K34415467-003-13-0, Z667611948, N-(4-[2-(Dimethylamino)ethoxy]benzyl)-3,4,5-trimethoxybenzamide #, N-[(4-{[2-(dimethylamino)ethyl]oxy}phenyl)methyl]-3,4,5-tris(methyloxy)benzamide
Theoretical properties:
molecular_formula: C21H28N2O5
molecular_weight: 388.5 g/mol
exact_mass: 388.19982200 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 10
heavy_atom_count: 28
topological_polar_surface_area: 69.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Trimethobenzamide is the amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans. It has a role as an antiemetic. It is a member of benzamides and a tertiary amino compound.
chebi: The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(<em>N</em>,<em>N</em>-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.
chembl: TRIMETHOBENZAMIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting.