Compound: AURAMINE
SMILES: N=C(c1ccc(N(C)C)cc1)c2ccc(N(C)C)cc2
InChIKey: JPIYZTWMUGTEHX-UHFFFAOYSA-N
Synonyms: AURAMINE, 492-80-8, Yellow pyoctanine, Glauramine, Auramine base, Auramine O base, Solvent Yellow 34, Auramine N base, Auramine OAF, Apyonine auramine base, Auramine SS, Auramine (free base), C.I. Solvent Yellow 34, Waxoline Yellow O, 4,4'-Dimethylaminobenzophenonimide, CI Solvent Yellow 34, 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline), CI Basic Yellow 2, free base, 4,4'-Carbonimidoylbis(N,N-dimethylaniline), Bis(p-dimethylaminophenyl)methyleneimine, Tetramethyl-p-diamino-imido-benzophenone, C.I. 41000B, CI 41000B, Aniline, 4,4'-imidocarbonylbis(N,N-dimethyl-, 4,4'-Carbonimidoylbis(N,N-dimethylbenzenamine), Aniline, 4,4'-(imidocarbonyl)bis(N,N-dimethyl-, Benzenamine, 4,4'-carbonimidoylbis(N,N-dimethyl-, 73O74R443B, DTXSID7043821, Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-, RefChem:1098885, DTXCID5023821, 207-762-5, 4-[4-(dimethylamino)benzenecarboximidoyl]-N,N-dimethylaniline, RCRA waste number U014, 4,4'-(Iminomethylene)bis(N,N-dimethylaniline), Caswell No. 063A, CCRIS 58, Auramine manufacture, auramine O free base, HSDB 2935, Auramine, manufacture of, Auramine, technical-grade, EINECS 207-762-5, RCRA waste no. U014, EPA Pesticide Chemical Code 039501, BRN 2215338, Auremine, Yellowpyoctanine, AI3-17282, UNII-73O74R443B, Auramine free base, C.I. Basic Yellow 2, Free Base, AURAMINE [IARC], Auramine Yellow (Salt/Mix), Benzophenoneidum (Salt/Mix), Oprea1_256545, SCHEMBL95306, Auramine, analytical standard, 4-14-00-00256 (Beilstein Handbook Reference), Basic Yellow 2 (Salt/Mix), orb1987354, CHEMBL1626329, CHEBI:51874, MSK5903, Tetramethyldiaminodiphenylacetimine, Auramine hydrochloride (Salt/Mix), 4,4'-Dimethylaminobenzophenone imine, MFCD00036224, STK525871, AKOS003193920, NCGC00091235-02, PD171473, NS00079853, ST50307101, EN300-33932, C19193, BIS(P-DIMETHYLAMINOPHENYL)METHYLENEIMINE [HSDB], Q26840770, (4-{[4-(dimethylamino)phenyl]iminomethyl}phenyl)dimethylamine
Theoretical properties:
molecular_formula: C17H21N3
molecular_weight: 267.37 g/mol
exact_mass: 267.173547683 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 4
heavy_atom_count: 20
topological_polar_surface_area: 30.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: YELLOW OR COLORLESS PLATES FROM ALCOHOL
color: YELLOW OR COLORLESS PLATES FROM ALCOHOL
melting_point: 136 °C
solubility: SOL IN ETHYL ETHER, VERY SOL IN ETHANOL.
vapor_pressure: 0.00000129 [mmHg]
Descriptions:
pubchem: Auramine can cause cancer according to an independent committee of scientific and health experts.
chebi: A member of the class of imines that is benzophenone imine carrying two dimethylamino substituents at positions 4 and 4'. The hydrochloride salt is the biological stain 'auramine O'
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Auramine O is a diarylmethane dye used as a fluorescent stain. In its pure form, Auramine O appears as yellow needle crystals. It is insoluble in water and soluble in ethanol and DMSO.
Auramine O can be used to stain acid-fast bacteria (e.g. Mycobacterium, where it binds to the mycolic acid in its cell wall) in a way similar to Ziehl–Neelsen stain. It can also be used as a fluorescent version of the Schiff reagent.
Auramine O can be used together with Rhodamine B as the Truant auramine-rhodamine stain for Mycobacterium tuberculosis. It can be also used as an antiseptic agent.