Compound: REMIFENTANIL
SMILES: O=C(OC)C1(N(c2ccccc2)C(=O)CC)CCN(CCC(=O)OC)CC1
InChIKey: ZTVQQQVZCWLTDF-UHFFFAOYSA-N
Synonyms: REMIFENTANIL, Remifentanyl, 132875-61-7, ramifentanyl, GI 87084X, Ultiva-, Remifentanilo, IDS-NR-005, P10582JYYK, 4-carboxy-4-(n-phenylpropionamido)-1-piperidinepropionic acid dimethyl ester, methyl 1-(3-methoxy-3-oxopropyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate, CHEBI:8802, DTXSID00157826, 1-Piperidinepropanoic acid, 4-(methoxy-carbonyl)-4-((1-oxopropyl)phenylamino)-, methyl ester, 4-(methoxycarbonyl)-4-((1-oxopropyl)phenylamino)-1-piperidinepropanoic acid methyl ester, remifentanilum, RefChem:57845, 3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester, DTXCID6080317, N01AH06, Ultiva, Remifentanil (INN), methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate, Ultiva (TN), REMIFENTANIL [INN], Remifentanil [INN:BAN], UNII-P10582JYYK, Remifentanil;, DEA No. 9739, REMIFENTANIL [MI], CHEMBL1005, REMIFENTANIL [VANDF], SCHEMBL36652, BIDD:GT0029, REMIFENTANIL [WHO-DD], GTPL7292, HSDB 8377, ZTVQQQVZCWLTDF-UHFFFAOYSA-N, GLXC-06399, DB00899, SB17331, DB-042144, NS00007756, C08021, D08473, L001266, Q417902, 1-Piperidinepropanoic acid, 4-(methoxycarbonyl)-4-[(1-oxopropyl)phenylamino]-, methyl ester, methyl 1-(3-methoxy-3-oxopropyl)-4-[phenyl(propanoyl)amino]piperidine-4-carboxylate
Theoretical properties:
molecular_formula: C20H28N2O5
molecular_weight: 376.4 g/mol
exact_mass: 376.19982200 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 9
heavy_atom_count: 27
topological_polar_surface_area: 76.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Oil
color: Oil
melting_point: Crystals from methanol + ether. MP: 212-214 °C /Remifentanil hydrochloride/
solubility: Soluble in methanol, ethyl acetate
Descriptions:
pubchem: Remifentanil is a piperidinecarboxylate ester that is methyl piperidine-4-carboxylate in which the hydrogen attached to the nitrogen is substituted by a 3-methoxy-3-oxopropyl group and the hydrogen at position 4 is substituted the nitrogen of N-propanoylaniline. It has a role as an opioid analgesic, a sedative, an intravenous anaesthetic and a mu-opioid receptor agonist. It is an anilide, a monocarboxylic acid amide, an alpha-amino acid ester and a piperidinecarboxylate ester.
chebi: A piperidinecarboxylate ester that is methyl piperidine-4-carboxylate in which the hydrogen attached to the nitrogen is substituted by a 3-methoxy-3-oxopropyl group and the hydrogen at position 4 is substituted the nitrogen of <em>N</em>-propanoylaniline.
chembl: REMIFENTANIL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Remifentanil, marketed under the brand name Ultiva is a potent, short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anesthetic.  Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. The use of remifentanil has made possible the use of high-dose opioid and low-dose hypnotic anesthesia, due to synergism between remifentanil and various hypnotic drugs and volatile anesthetics.