Compound: diosmin
SMILES: O=c1c2c(oc(c1)-c3cc(O)c(OC)cc3)cc(O[C@@H]4O[C@@H]([C@@H](O)[C@@H]([C@H]4O)O)CO[C@@H]5O[C@H]([C@H](O)[C@H]([C@H]5O)O)C)cc2O
InChIKey: GZSOSUNBTXMUFQ-YFAPSIMESA-N
Synonyms: diosmin, 520-27-4, Barosmin, Diosmine, Venosmine, Flebosten, Tovene, Ven-Detrex, Diovenor, Buchu Resin, Litosmil, flebosmil, Diosminum, Diosmetin 7-O-rutinoside, Diosven, Flebaven, Flebavena, Hemerven, Insuven, Varinon, Dioven, Diosmina, 7QM776WJ5N, DTXSID4045892, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one, NSC-758417, 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside, CHEBI:4631, DTXCID2025892, 3',5,7-trihydroxy-4'-methoxyflavone 7-rhamnoglucoside, 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chromen-4-one, 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, diosmiplex, Vasculera, Resin, Buchu, 5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl)oxymethyl)tetrahydropyran-2-yl)oxy-chromen-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl)oxan-2-yl)oxychromen-4-one, RefChem:35045, C05CA03, 208-289-7, Diosimin, Diosmil, Veno-V, Diosmetin-7-O-rutinoside, MFCD00009772, Rioven, Diosmin [INN], 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one, Diosmin (INN), 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, Diosmin, analytical standard, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside, CAS-520-27-4, Diosmin [INN:BAN], Diosmin [INN-Spanish], Diosmine [INN-French], Diosminum [INN-Latin], SR-01000799147, 3',5,7-Trihydroxy-4'-methoxyflavone 7-rutinoside, UNII-7QM776WJ5N, CCRIS 7915, Barosmin;, Daflon;, Diosmin CRS, Ven-Detrex;, NCGC00095022-01, 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, Diosmin (Standard), EINECS 208-289-7, Daflon (TN), diosmetin-7-rutinose, Diosmin (8), SE 4601, Diosmin - 90%, Salinigricoflavonoloside;, Diosmetin 7-rutinoside;, DIOSMIN [DSC], DIOSMIN [MI], Diosmetin 7-b-rutinoside, DIOSMIN [MART.], DIOSMIN [USP-RS], DIOSMIN [WHO-DD], 3',5,7-Trihydroxy-4'-methoxyflavone-7-(6-O-(-deoxy-alpha-L-mannopyraonsyl)-beta-D-glucopyranoside, MLS001304032, SCHEMBL120870, diosmetin-7-O-beta-D-rutinose, DIOSMIN [EP MONOGRAPH], CHEMBL231884, orb1310207, orb3139707, SCHEMBL29368789, SCHEMBL29449210, SCHEMBL29558633, Diosmin for Sheperd's purse CRS, HY-N0178R, 3',5-Dihydroxy-4'-methoxy-4-oxo-4H-chromen-7-ylrutosid, BDBM153267, GLXC-13353, HMS2233P16, HMS3713L08, Diosmin for system suitability CRS, Tox21_111392, trihydroxymethoxyflavone-O-rutinoside, 3',5-Dihydroxy-4'-methoxy-4-oxo-4H-chromen-7-ylrutosid [IUPAC], EBC-27379, s2292, AKOS015969767, Tox21_111392_1, CCG-208570, DB08995, NSC 758417, OD11673, SMP1_000183, NCGC00344564-01, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-((6-O-alpha-L-rhamnopyranosyl-beta-D-glycopyranosyl)oxy)-4-chromenon, 5-HYDROXY-2-(3-HYDROXY-4-METHOXYPHENYL)-7-{[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-({[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYLOXAN-2-YL]OXY}METHYL)OXAN-2-YL]OXY}-4H-CHROMEN-4-ONE, 7-[6-O-Deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl)oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, AS-13224, BP-12422, SMR000718616, SY076010, NS00005135, C10039, D07858, EN300-18388399, 3',5,7-trihydroxy-4'-methoxy flavone-7-rutinoside, Q2607865, SR-01000799147-4, SR-01000799147-5, SR-01000799147-6, 3?,5,7-Trihyd  roxy-4?-methoxyflavone 7-rutinoside, BRD-K94436377-001-10-2, BRD-K94436377-001-11-0, Diosmin, European Pharmacopoeia (EP) Reference Standard, Diosmin, United States Pharmacopeia (USP) Reference Standard, Diosmin for system suitability, European Pharmacopoeia (EP) Reference Standard, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-?-L-mannopyranosyl)-?-D-glucopyranoside, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chrome, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(O6-alpha-L-rhamnopyranosyl-beta-D-glucopyranosyloxy)chromen-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one, 7-((6-O-(6-DEOXY-GA-L-MANNOPYRANOSYL)-.BETA.-D-GLUCOPYRANOSYL)OXY)-5-HYDROXY-2-(3-HYDROXY-4-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE, 7-((6-O-(6-Deoxy-ga-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
Theoretical properties:
molecular_formula: C28H32O15
molecular_weight: 608.5 g/mol
exact_mass: 608.17412031 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 8
hydrogen_bond_acceptor_count: 15
rotatable_bond_count: 7
heavy_atom_count: 43
topological_polar_surface_area: 234 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
boiling_point: 926.8±65.0
melting_point: 277-278
Descriptions:
pubchem: Diosmin is a disaccharide derivative that consists of diosmetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and an anti-inflammatory agent. It is a monomethoxyflavone, a rutinoside, a dihydroxyflavanone, a glycosyloxyflavone and a disaccharide derivative. It is functionally related to a diosmetin.
chebi: A disaccharide derivative that consists of  diosmetin substituted by a 6-<em>O</em>-(α-<small>L</small>-rhamnopyranosyl)-β-<small>D</small>-glucopyranosyl moiety at position 7 via a glycosidic linkage.
chembl: DIOSMIN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Diosmin (diosmetin 7-O-rutinoside), a flavone glycoside of diosmetin, is manufactured from citrus fruit peels as a phlebotonic non-prescription dietary supplement used to aid treatment of hemorrhoids or chronic venous diseases, mainly of the legs.