Compound: bis-tris
SMILES: OCC(N(CCO)CCO)(CO)CO
InChIKey: OWMVSZAMULFTJU-UHFFFAOYSA-N
Synonyms: bis-tris, 6976-37-0, Bistris, 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol, 2-(Bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)propane-1,3-diol, Q1XC3631CP, CHEBI:41250, 1,3-Propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-, NSC-24868, NSC-119932, 1,3-Propanediol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-, 2,2-Bis[hydroxymethyl]-2,2',2''-nitrilotriethanol, RefChem:569580, bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane, 2-(bis(2-hydroxyethyl)amino)-2(hydroxymethyl)-1,3-propanediol, 2,2-BIS(HYDROXYETHYL)-(IMINOTRIS)-(HYDROXYMETHYL)METHANE, 230-237-7, 686-880-2, Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane, MFCD00002853, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane, 2,2-Bis(hydroxymethyl)-2,2,2-nitrilotriethanol, 2-(Bis(2-hydroxyethyl)amino))-2-hydroxymethyl-1,3-propanediol, Bis-(2-hydroxyethyl)aminotris(hydroxymethyl)methane, Bistris; NSC 119932; NSC 24868; NuPage Bis-Tris, Bis(2-hydroxyethyl)iminotris(hydroxymethyl)methane BIS-TRIS, 1, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-, UNII-Q1XC3631CP, 2-[Bis(2-hydroxyethyl)amino)]-2-hydroxymethyl-1,3-propanediol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-1,3-propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol, 2,2-Bis(hydroxymethyl)-2,2',2"-nitrilotriethanol, EINECS 230-237-7, NSC 24868, NSC 119932, GlyTouCan:G90356ZC, Epitope ID:161731, Bis-hydroxyethyl tromethamine, SCHEMBL35757, orb1305871, DTXSID6064537, SCHEMBL14110358, G90356ZC, HY-D0856, NSC24868, NSC119932, AKOS015964206, BIS-TRIS, >=98.0% (titration), FB15824, SB78428, AS-89673, BP-20533, PD069504, SY012935, BIS-TRIS, BioUltra, >=99.0% (NT), BIS-TRIS, BioXtra, >=99.0% (NT), CS-0015166, NS00021335, BIS-TRIS, BioXtra, >=98.0% (titration), 2,2-Bishydroxymethyl-2,2',2''-nitriloethanol, D70475, F045157, Q865956, SR-01000883740, Bis(2-hydroxyethyl)-(iminotris)hydroxymethyl)methane, SR-01000883740-1, BIS-2-HYDROXY-IMINO-TRIS-HYDROXYMETHYL-METHANE, BIS-TRIS, anhydrous, free-flowing, Redi-Dri(TM), >=98.0%, 2,2 - BIS(HYDROXYETHYL)-(IMINOTRIS)-(HYDROXYMETHYL)METHANE, 2-[Bis(2-hydroxyethyl)imino]-2-(hydroxymethyl)-1,3-propanediol, BIS-TRIS, Vetec(TM) reagent grade, >=98%, RNase and DNase free, BIS-TRIS, BioPerformance Certified, cell culture tested, suitable for insect cell culture, >=98.0%
Theoretical properties:
molecular_formula: C8H19NO5
molecular_weight: 209.24 g/mol
exact_mass: 209.12632271 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 5
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 8
heavy_atom_count: 14
topological_polar_surface_area: 104 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Bis-tris is a buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; pKa = 6.46 at 25 C. It has a role as a buffer. It is functionally related to a member of tris.
chebi: A buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; p<em>K</em><small><sub>a</sub></small> = 6.46 at 25 °C.
wikipedia: Bis-tris methane, also known as BIS-TRIS or BTM, is a buffering agent used in biochemistry.  Bis-tris methane is an organic tertiary amine with labile protons having a pKa of 6.46 at 25 °C. It is an effective buffer between the pH 5.8 and 7.2. Bis-tris methane binds strongly to Cu and Pb ions as well as, weakly, to Mg, Ca, Mn, Co, Ni, Zn and Cd.