Compound: Phlorizin
SMILES: O=C(c1c(O[C@@H]2O[C@@H]([C@@H](O)[C@@H]([C@H]2O)O)CO)cc(O)cc1O)CCc3ccc(O)cc3
InChIKey: IOUVKUPGCMBWBT-QNDFHXLGSA-N
Synonyms: Phlorizin, Phlorhizin, Phlorizoside, Floridzin, Phlorrhizin, Phloretin 2'-glucoside, Phlorrhizen, Phloridzinum, Phloretin-2'-O-beta-glucoside, CU9S17279X, NSC-2833, phloretin 2'-O-glucoside, 1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one, 2'-(beta-D-Glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone, CHEBI:8113, DTXSID3075339, 1-Propanone, 1-(2-(beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one, 1-Propanone, 1-[2-(beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-, Phloridzin Phenolic, 1-(2,4-dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one, 1-(2,4-dihydroxy-6-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyphenyl)-3-(4-hydroxyphenyl)propan-1-one, Phloridzin 1535, RefChem:57854, DTXCID1042738, 200-487-1, Phloridzosid, AI3-19835, 1-[2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Phloretin-2'-O-glucoside, Phloretin-2'-beta-glucoside, CHEMBL245067, Phloretin-2'-O-.beta.-glucoside, MFCD00006591, 1-Propanone,1-[2-(b-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-, 1-(2,4-dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one, NSC 2833, Phlorizin (dihydrate), 1-[2,4-dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-phenyl]-3-(4-hydroxyphenyl)propan-1-one, 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl beta-D-glucopyranoside, 2'-(.beta.-D-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone, 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one, 1-{6-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydr opyran-2-yloxy)]-2,4-dihydroxyphenyl}-3-(4-hydroxyphenyl)propan-1-one, 112318-65-7, SR-01000781913, EINECS 200-487-1, Lopin, UNII-CU9S17279X, phloretin-hexoside, 1-Propanone, 1-[2-(.beta.-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-, O-glucoside, 1, 1-PROPANONE, 1-(2-(.BETA.-D-GLUCOPYRANOSYLOXY)-4,6-DIHYDROXYPHENYL)-3-(4-HYDROXYPHENYL)-, Phlorizin (Standard), Phlorizin (Phloridzin), Spectrum_001291, PHLORIDZIN [MI], SpecPlus_000325, Spectrum2_000701, Spectrum3_001227, Spectrum4_001651, Spectrum5_000521, PHLORIDZINUM [HPUS], PHLORIDZIN [WHO-DD], SCHEMBL17290, BSPBio_002674, KBioGR_002141, KBioSS_001771, SPECTRUM300547, JMC511145 Compound 1, DivK1c_006421, SPBio_000881, GTPL4757, orb1304840, orb3139903, BDBM20875, HY-N0143R, KBio1_001365, KBio2_001771, KBio2_004339, KBio2_006907, KBio3_002174, GLXC-10564, HMS2090P10, Phloretin 2'-?-D-glucopyranoside, Phloretin 2'-ss-D-glucopyranoside, HY-N0143, MSK40016, CCG-38341, s2343, SBB005924, 4,6-dihydroxy-2-(beta-D-glucosido)-beta-(p-hydroxyphenyl)propiophenone, AKOS015920054, AC-7976, CS-2013, EBC-615928, MP08132, SDCCGMLS-0066626.P001, 1-[2-(?-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, NCGC00142423-01, NCGC00142423-02, NCGC00142423-06, NCGC00142423-11, AS-15724, ST055878, ST057167, SY030366, NS00002475, P0248, C01604, F079095, Q413105, SR-01000781913-2, SR-01000781913-4, SR-01000781913-5, BRD-K73756878-001-02-9, 1-[2-(.beta.-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, 1-[2-(ss-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, 1-{2,4-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydropy ran-2-yloxy)]phenyl}-3-(4-hydroxyphenyl)propan-1-one, hydrate, LN9
Theoretical properties:
molecular_formula: C21H24O10
molecular_weight: 436.4 g/mol
exact_mass: 436.13694696 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 7
hydrogen_bond_acceptor_count: 10
rotatable_bond_count: 7
heavy_atom_count: 31
topological_polar_surface_area: 177 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 110.0 °C
solubility: 1 mg/mL at 22 °C
Descriptions:
pubchem: Phlorizin is an aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2' via a glycosidic linkage. It has a role as an antioxidant and a plant metabolite. It is an aryl beta-D-glucoside, a monosaccharide derivative and a member of dihydrochalcones. It is functionally related to a phloretin.
chebi: An aryl β-<small>D</small>-glucoside that is  phloretin attached to a  β-<small>D</small>-glucopyranosyl residue at position 2' via a glycosidic linkage.
chembl: PHLORIZIN is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Phlorizin  is a glucoside of phloretin, a dihydrochalcone. A white solid when pure, samples often appear yellow due to impurities. It is of sweet taste and contains four molecules of water in the crystal. It is poorly soluble in ether and cold water, but soluble in ethanol and hot water.  Upon prolonged exposure to aqueous solutions, phlorizin hydrolyzes to phloretin and glucose.