Compound: pheniramine
SMILES: n1c(cccc1)C(c2ccccc2)CCN(C)C
InChIKey: IJHNSHDBIRRJRN-UHFFFAOYSA-N
Synonyms: pheniramine, Prophenpyridamine, Tripoton, Pyriton, 86-21-5, Propheniramine, Feniramina, Pheniraminum, dimethyl[3-phenyl-3-(pyridin-2-yl)propyl]amine, 2-(alpha-(2-Dimethylaminoethyl)benzyl)pyridine, NSC-47965, 134FM9ZZ6M, 2-Pyridinepropanamine, N,N-dimethyl-gamma-phenyl-, DTXSID0023454, Pyridine, 2-(alpha-(2-(dimethylamino)ethyl)benzyl)-, dimethyl(3-phenyl-3-(pyridin-2-yl)propyl)amine, (+-)-Pheniramine, RefChem:860603, DTXCID203454, D04AA16, R06AB05, 201-656-2, Feniramine, Feniramina [INN-Spanish], Pheniraminum [INN-Latin], 2-(3-Dimethylamino-1-phenylpropyl)pyridine, 1-Phenyl-1-(2-pyridyl)-3-dimethylaminopropane, N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine, N,N-Dimethyl-3-phenyl-3-(2-pyridyl)propylamine, NCI-C60695, NSC 47965, Pheniramine (INN), 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylanine, 2-Pyridinepropanamine, N,N-dimethyl-.gamma.-phenyl-, Prophenpyridamine; Pyriton, 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylamine, CHEMBL1193, 2-[.alpha.-[2-(Dimethylamino)ethyl]benzyl]pyridine, 2-[.alpha.-(2-Dimethylaminoethyl)benzyl]pyridine, N,N-Dimethyl-3-phenyl-3-(2-pyridinyl)-1-propanamine, N,N-dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine, PHENIRAMINE [INN], Pheniramine [INN:BAN], Pyridine, 2-[.alpha.-[2-(dimethylamino)ethyl]benzyl]-, p-Aminosalicylsaures salz, EINECS 201-656-2, 2-(.ALPHA.-(2-DIMETHYLAMINOETHYL)BENZYL)PYRIDINE, BRN 0192445, UNII-134FM9ZZ6M, PYRIDINE, 2-(.ALPHA.-(2-(DIMETHYLAMINO)ETHYL)BENZYL)-, Dimethyl(3-phenyl-3-(2-pyridyl)propyl)amine, Brompheniramine Maleate Imp. C (EP); Brompheniramine Imp. C (EP); (3RS)-N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine; Pheniramine; Brompheniramine Maleate Impurity C; Brompheniramine Impurity C, Metron (Salt/Mix), Inhiston (Salt/Mix), Spectrum_001075, Dexchlorpheniramine Maleate EP Impurity A, PHENIRAMINE [MI], Prestwick0_000059, Prestwick1_000059, Prestwick2_000059, Prestwick3_000059, Spectrum2_001277, Spectrum3_000760, Spectrum4_000966, Spectrum5_001028, PHENIRAMINE [VANDF], PM 241 (Salt/Mix), SCHEMBL4796, PHENIRAMINE [MART.], Lopac0_000981, Oprea1_875595, (+/-)-PHENIRAMINE, BSPBio_000217, BSPBio_002380, KBioGR_001311, KBioSS_001555, PHENIRAMINE [WHO-DD], 5-22-10-00487 (Beilstein Handbook Reference), DivK1c_000235, N,N-dimethyl-3-phenyl-3-(2-pyridyl)propan-1-amine, SPBio_001274, SPBio_002138, BPBio1_000239, GTPL7267, SCHEMBL5063017, SCHEMBL30182646, CHEBI:91591, KBio1_000235, KBio2_001555, KBio2_004123, KBio2_006691, KBio3_001600, NINDS_000235, WLN: T6NJ BYR&2N1&1, NSC47965, Pheniramine 1.0 mg/ml in Methanol, BDBM50017656, EBC-26282, STL329242, AKOS022110089, CCG-205061, DB01620, SDCCGSBI-0050954.P005, IDI1_000235, NCGC00015831-02, NCGC00015831-03, NCGC00015831-07, NCGC00015831-12, NCGC00162306-01, LS-14507, SBI-0050954.P004, DB-056919, AB00053521, NS00000468, D08355, 2-Pyridinepropanamine,N-dimethyl-.gamma.-phenyl-, AB00053521_18, AB00053521_19, Pyridine, 2[alpha-(2-dimethylaminoethyl)benzyl], Dimethyl-(3-phenyl-3-pyridin-2-yl-propyl)-amine, EN300-18563895, Q656259, pyridine, 2-(alpha-(2-dimethylaminoethyl)benzyl)-, BRD-A23072235-050-05-2, BRD-A23072235-050-09-4, BRD-A23072235-050-17-7, BRD-A23072235-050-18-5, 1-PHENYL-1-(2-PYRIDYL)-3-DI-METHYLAMINOPROPANE, N,N-Dimethyl-3-phenyl-3-(2-pyridinyl)-1-propanamine #, N,N-DIMETHYL-.GAMMA.-PHENYL-2-PYRIDINEPROPANAMINE, Chlorpheniramine Impurity 13Dexchlorpheniramine EP Impurity A, 155683-10-6, Pheniramine; Brompheniramine Maleate EP Impurity C; Dexchlorpheniramine Maleate EP Impurity A
Theoretical properties:
molecular_formula: C16H20N2
molecular_weight: 240.34 g/mol
exact_mass: 240.162648646 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 5
heavy_atom_count: 18
topological_polar_surface_area: 16.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: 3.77e-01 g/L
Descriptions:
pubchem: N,N-dimethyl-3-phenyl-3-(2-pyridinyl)-1-propanamine is a member of pyridines and a tertiary amino compound.
chembl: PHENIRAMINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.
It was patented in 1948. Pheniramine is generally sold in combination with other medications, rather than as a stand-alone drug, although some formulations are available containing pheniramine by itself.