Compound: Bazedoxifene
SMILES: O(c1ccc(Cn2c(-c3ccc(O)cc3)c(C)c4c2ccc(c4)O)cc1)CCN5CCCCCC5
InChIKey: UCJGJABZCDBEDK-UHFFFAOYSA-N
Synonyms: Bazedoxifene, 198481-32-2, Conbriza, Bazedoxifeno, TSE-424, Q16TT9C5BK, 1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-, WAY 140424, 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol, DTXSID70173593, TSE424, 1-({4-[2-(azepan-1-yl)ethoxy]phenyl}methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, 1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-, bazedoxifenum, 1-((4-(2-(azepan-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, 1-((4-(2-(azepan-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methylindol-5-ol, RefChem:116748, DTXCID3096084, G03XC02, Viviant, Bazedoxifene [INN], C30H34N2O3, 1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, CHEMBL46740, 1-[[4-[2-(AZEPAN-1-YL)ETHOXY]PHENYL]METHYL]-2-(4-HYDROXYPHENYL)-3-METHYL-INDOL-5-OL, 1-[4-(2-Azepan-1-yl-ethoxy)-benzyl]-2-(4-hydroxy-phenyl)-3-methyl-1H-indol-5-ol, Bazedoxifene free base, UNII-Q16TT9C5BK, Bazedoxifeno [INN-Spanish], Bazedoxifene?, 1-{4-[2-(azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, 1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-; 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol; Bazedoxifene; WAY 140424, 198481-32-2 (free base), MFCD05148441, Bazedoxifene (Standard), BAZEDOXIFENE [MI], BAZEDOXIFENE [VANDF], SCHEMBL41935, orb341885, BAZEDOXIFENE [WHO-DD], GTPL7355, orb3027356, BAZEDOXIFENE [EMA EPAR], SCHEMBL29370682, HY-A0031R, CHEBI:135947, UCJGJABZCDBEDK-UHFFFAOYSA-N, EX-A5409, HY-A0031, MSK11395, BDBM50099585, EBC-27177, NSC823462, AKOS030255808, AK R215 COMPONENT BAZEDOXIFENE, AK-R215 COMPONENT BAZEDOXIFENE, CS-0932, DB06401, NSC-823462, SB19326, 1-((4-(2-Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, AS-78494, US8815934, No. 98, DB-345621, NS00007594, D94589, AB01566901_01, EN300-20600169, Q4875166, BRD-K90195324-003-02-5, BRD-K90195324-003-03-3, 1-(P-(2-(HEXAHYDRO-1H-AZEPIN-1-YL)ETHOXY)BENZYL)-2-(P-HYDROXYPHENYL)-3-METHYLINDOL-5-OL
Theoretical properties:
molecular_formula: C30H34N2O3
molecular_weight: 470.6 g/mol
exact_mass: 470.25694295 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 7
heavy_atom_count: 35
topological_polar_surface_area: 57.9 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Bazedoxifene is a phenylindole.
chembl: BAZEDOXIFENE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Bazedoxifene, used as bazedoxifene acetate, is a medication for bone problems and possibly (pending more study) for cancer. It is a third-generation selective estrogen receptor modulator (SERM). Since late 2013 it has had U.S. FDA approval for bazedoxifene as part of the combination drug Duavee in the prevention (not treatment) of postmenopausal osteoporosis. It is also being studied for possible treatment of breast cancer and pancreatic cancer.