Compound: 2,3,5,6-Tetramethylpyrazine
SMILES: n1c(c(nc(c1C)C)C)C
InChIKey: FINHMKGKINIASC-UHFFFAOYSA-N
Synonyms: 2,3,5,6-Tetramethylpyrazine, TETRAMETHYLPYRAZINE, 1124-11-4, Ligustrazine, Chuanxiongzine, Tetrapyrazine, chuanxingzine, FEMA No. 3237, TMPZ, 2,3,5,6,-Tetramethyl-1,4-pyrazine, V80F4IA5XG, CHUANXIONGQIN, DTXSID6047070, NSC-36080, NSC-46451, DTXCID4027070, CHEBI:133246, tetramethyl pyrazine, RefChem:799162, 214-391-2, Pyrazine, tetramethyl-, Bs factor, Tetramethylpyrazin, Ligustizine, 2,3,5,6-Tetramethyl pyrazine, Liqustrazine, MFCD00006146, MLS000069594, FEMA 3237, Pyrazine, 2,3,5,6-tetramethyl-, SMR000059042, 2,5,6-Tetramethylpyrazine, EINECS 214-391-2, NSC 36080, NSC 46451, UNII-V80F4IA5XG, 2,3,5,6-Tetramethylpyrazine (natural), Ligustrazin, Ligustrazine;, Ligustrazine (Standard), Opera_ID_849, TMP?, SCHEMBL77624, LIGUSTRAZINE [WHO-DD], CHEMBL303697, orb1305113, orb3139114, SCHEMBL4681937, FINHMKGKINIASC-UHFFFAOYSA-, HY-N0264R, 2,3,5,6-Tetra-methyl-pyrazine, Pyrazine, 2,3,5,6-tetramethyl, GLXC-10218, HMS2235K03, HMS3371J08, HMS5082F07, HY-N0264, MSK10407, NSC36080, NSC46451, Tox21_302313, BBL012277, EBC-12525, s3956, SBB085945, STL163591, 2,3,5,6-Tetramethylpyrazine, 98%, AKOS003398567, CCG-207974, CS-W023183, FT04172, NCGC00247063-01, NCGC00256097-01, AC-10515, AC-34076, AS-13206, SY011353, CAS-1124-11-4, DB-003786, 2,3,5,6-TETRAMETHYLPYRAZINE [FCC], NS00013238, ST45025457, 2,3,5,6-TETRAMETHYLPYRAZINE [FHFI], 2,3,5,6-Tetramethylpyrazine, >=98%, FG, EN300-113945, F11202, 2,3,5,6-Tetramethylpyrazine, analytical standard, AC-907/25014219, F078918, 2,3,5,6-Tetramethylpyrazine, natural, >=98%, FG, BRD-K25691735-001-09-5, Q11319317, Z1741976694, 2,3,5,6-Tetramethylpyrazine, Vetec(TM) reagent grade, 98%, InChI=1/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
Theoretical properties:
molecular_formula: C8H12N2
molecular_weight: 136.19 g/mol
exact_mass: 136.100048391 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 0
heavy_atom_count: 10
topological_polar_surface_area: 25.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
boiling_point: 190.00 °C. @ 760.00 mm Hg
melting_point: 86 °C
solubility: slightly soluble in water; soluble in oils, propylene glycol, organic solvents
Descriptions:
pubchem: Tetramethylpyrazine is a member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii). It has a role as an antineoplastic agent, a vasodilator agent, a platelet aggregation inhibitor, a neuroprotective agent, an apoptosis inhibitor and a bacterial metabolite. It is an alkaloid and a member of pyrazines.
chebi: A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (<em>Ligusticum  wallichii</em>).
chembl: LIGUSTRAZINE is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Alkylpyrazines are chemical compounds based on pyrazine with different substitution patterns.  Some alkylpyrazines are naturally occurring highly aromatic substances which often have a very low odor threshold and contribute to the taste and aroma of various foods including cocoa, baked goods, coffee and wines.  Alkylpyrazines are also formed during the cooking of some foods via Maillard reactions.