Compound: Steviol
SMILES: O=C(O)[C@]1([C@@H]2[C@]([C@H]3[C@@]4(CC(=C)[C@](C4)(O)CC3)CC2)(CCC1)C)C
InChIKey: QFVOYBUQQBFCRH-VQSWZGCSSA-N
Synonyms: Steviol, 471-80-7, (-)-Steviol, Hydroxydehydrostevic acid, 4741LYX6RT, DTXSID50897427, (14-alpha)-13-Hydroxykaur-16-en-18-oic acid, CHEBI:145024, NSC-226902, (1R,4S,5R,9S,10R,13S)-13-hydroxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid, Kaur-16-en-18-oic acid, 13-hydroxy-, (4alpha)-, (1R,4S,5R,9S,10R,13S)-13-hydroxy-5,9-dimethyl-14-methylidenetetracyclo(11.2.1.01,10.04,9)hexadecane-5-carboxylic acid, RefChem:185727, DTXCID401326770, (4R,4aS,6aR,9S,11aR,11bS)-9-Hydroxy-4,11b-dimethyl-8-methylidenetetradecahydro-6a,9-methanocyclohepta(a)naphthalene-4-carboxylic acid, MFCD00210558, (4R,4aS,6aR,9S,11aR,11bS)-9-hydroxy-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid, Kaur-16-en-18-oic acid, 13-hydroxy-, (4.alpha.)-, 13-Hydroxykaurenoic acid, 13alpha-hydroxy-5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid, Steviol hydrate, UNII-4741LYX6RT, CCRIS 2588, 13-Hydroxykaur-16-en-18-oic acid, QFVOYBUQQBFCRH-VQSWZGCSSA-N, Steviol (Standard), NSC 226902, STEVIOL(P), STEVIOSIDE AGLYCON, STEVIOL [MI], ent-13-Hydroxy-kauran-16-en-19-oic acid, REBAUDIOSIDES AGLYCON, Steviol, analytical standard, SCHEMBL28608, CHEMBL463996, HY-N2057R, HMS3263G10, Steviol (Hydroxydehydrostevic acid), HY-N2057, Tox21_501074, BDBM50480263, s3272, AKOS037514919, CCG-222378, EBC-618489, FS65877, LP01074, SDCCGSBI-0633785.P001, NCGC00186036-01, NCGC00186036-04, NCGC00261759-01, DA-58111, SY075770, (4?)-13-Hydroxykaur-16-en-18-oic acid, CS-0018546, NS00124653, C20212, Q426852, (4.ALPHA.)-13-HYDROXYKAUR-16-EN-18-OIC ACID, Kaur-16-en-18-oic acid, 13-hydroxy-, (14-alpha)-, (1R,4S,5R,9S,10R,13S)-13-hydroxy-5,9-dimethyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid, (1R,4S,5R,9S,10R,13S)-13-hydroxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylic acid
Theoretical properties:
molecular_formula: C20H30O3
molecular_weight: 318.4 g/mol
exact_mass: 318.21949481 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 1
heavy_atom_count: 23
topological_polar_surface_area: 57.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Steviol is an ent-kaurane diterpenoid that is 5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group. It has a role as an antineoplastic agent. It is a tertiary allylic alcohol, a monocarboxylic acid, a bridged compound, an ent-kaurane diterpenoid and a tetracyclic diterpenoid. It is a conjugate acid of a steviol(1-).
chebi: An <em>ent</em>-kaurane diterpenoid that is 5β,8α,9β,10α-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group.
chembl: STEVIOL is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Steviol glycosides are the chemical compounds responsible for the sweet taste of the leaves of the South American plant Stevia rebaudiana (Asteraceae) and the main ingredients (or precursors) of many sweeteners marketed under the generic name stevia and several trade names.  They also occur in the related species S. phlebophylla (but in no other species of Stevia) and in the plant Rubus chingii (Rosaceae).
Steviol glycosides from Stevia rebaudiana have been reported to be between 30 and 320 times sweeter than sucrose, although there is some disagreement in the technical literature about these numbers. They are heat-stable, pH-stable, and do not ferment.  
Steviol glycosides do not induce a glycemic response when ingested, because humans cannot metabolize stevia. The acceptable daily intake (ADI) for steviol glycosides, expressed as steviol equivalents, has been established to be 4 mg/kg body weight/day, and is based on no observed adverse effects of a 100 fold higher dose in a rat study.