Compound: uridine
SMILES: O=c1n(ccc([nH]1)=O)[C@@H]2O[C@H](CO)[C@H]([C@H]2O)O
InChIKey: DRTQHJPVMGBUCF-XVFCMESISA-N
Synonyms: uridine, 58-96-8, Uridin, Uracil riboside, 1-beta-D-Ribofuranosyluracil, CHEBI:16704, WHI7HQ7H85, DTXSID40891555, NSC-20256, NSC20256, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione, 1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione, Allo Uridine, Allo-Uridine, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidine-2,4-dione, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione, RefChem:6340, DTXCID001030648, 200-407-5, Uracil, 1-beta-D-ribofuranosyl-, MFCD00006526, 1-.beta.-D-Ribofuranosyluracil, d-uridine, beta-Uridine, NSC 20256, AI3-52690, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, Urd, C9H12N2O6, MLS000069625, SMR000058222, 92487-68-8, 69-75-0, 1-beta-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione (Uridine), b-Uridine, Uridine-15N2, 1-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dihydropyrimi dine-2,4-dione, EINECS 200-407-5, UNII-WHI7HQ7H85, araU, Uridine-t, d-Ribosyl uracil, .beta.-Uridine, Uridine (Standard), Adenosine Impurity 8, 1af2, 4jx9, 4pd6, Opera_ID_118, Uridine, >=99%, URIDINE [MI], URIDINE [MART.], 1-b-D-Ribofuranosyluracil, URIDINE [USP-RS], URIDINE [WHO-DD], 1-A-D-Ribofuranosyluracil, bmse000158, bmse000816, bmse000864, Epitope ID:149164, 1-.beta.-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione, beta-D-ribofuranosyl-uridine, SCHEMBL20667, Uracil-1-A-D-ribofuranoside, rg2417, Uridine, BioUltra, >=99%, Uracil-1-beta-d-ribofuranoside, URIDINE [USP IMPURITY], CHEMBL100259, GTPL4566, SCHEMBL3370976, SCHEMBL8600376, SCHEMBL9177985, SCHEMBL9179675, 1-beta-delta-Ribofuranosyluracil, HY-B1449R, MSK6806, Uracil-1-.beta.-d-ribofuranoside, HMS2230P13, HMS3884M20, HY-B1449, BDBM50088517, EBC-08618, s2029, SBB000838, AKOS015896922, CCG-214447, CS-5153, DB02745, NU06309, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, SMP1_000029, NCGC00017312-02, NCGC00017312-04, NCGC00017312-05, NCGC00142368-01, BP-58653, DS-14345, SRI-10895_12, ST023512, SY005419, Uridine, Vetec(TM) reagent grade, 99%, ADENOSINE IMPURITY F [EP IMPURITY], DB-030519, NS00014580, U0020, C00299, EN300-221746, 1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione, b-D-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1, F078878, Q422573, BRD-K13050303-001-17-3, BRD-K13050303-001-18-1, Uridine, powder, BioReagent, suitable for cell culture, .beta.-D-Ribofuranoside, 2,4(1H,3H)-pyrimidinedione-1, 1-beta-delta-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione, 6B6FA3F8-70A2-44EA-B99C-D35D0A9237AA, beta-delta-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1, Z1741976658, Uridine; Adenosine EP Impurity F; Cytarabine EP Impurity B, 1-.BETA.-D-RIBOFURANOSYLPYRIMIDINE-2,4(1H,3H)-DIONE, 1-beta-D-Ribofuranosyluracil, Uracil-1-beta-D-ribofuranoside, Uridine, United States Pharmacopeia (USP) Reference Standard
Theoretical properties:
molecular_formula: C9H12N2O6
molecular_weight: 244.20 g/mol
exact_mass: 244.06953611 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 2
heavy_atom_count: 17
topological_polar_surface_area: 119 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: 34.9 [ug/mL] (The mean of the results at pH 7.4)
Descriptions:
pubchem: Uridine is a ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a betaN1-glycosidic bond. It has a role as a drug metabolite, a human metabolite and a fundamental metabolite. It is functionally related to a uracil.
chebi: A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a β‒N<small><sup>1</small></sup>-glycosidic bond.
chembl: URIDINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Uridine (symbol U or Urd) is a glycosylated pyrimidine analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond. The analog is one of the five standard nucleosides which make up nucleic acids, the others being adenosine, thymidine, cytidine and guanosine. The five nucleosides are commonly abbreviated to their symbols, U, A, dT, C, and G, respectively. However, thymidine is more commonly written as 'dT' ('d' represents 'deoxy') as it contains a 2'-deoxyribofuranose moiety rather than the ribofuranose ring found in uridine. This is because thymidine is found in deoxyribonucleic acid (DNA) and usually not in ribonucleic acid (RNA). Conversely, uridine is found in RNA and not DNA. The remaining three nucleosides may be found in both RNA and DNA. In RNA, they would be represented as A, C and G whereas in DNA they would be represented as dA, dC and dG.