Compound: MMAF
SMILES: O=C(O)[C@@H](NC(=O)[C@@H]([C@@H](OC)[C@H]1N(C(=O)C[C@@H](OC)[C@@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C)C)[C@H](CC)C)CCC1)C)Cc2ccccc2
InChIKey: MFRNYXJJRJQHNW-DEMKXPNLSA-N
Synonyms: MMAF, 745017-94-1, Monomethyl Auristatin F, DTXSID601031563, 1Z1AI9IW5L, MMAF peptide, RefChem:926092, DTXCID201516583, Monomethylauristatin F, MFCD25976742, MMAF (GMP), (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid, MONOMETHYLAURISTATIN PHENYLALANINE, (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-Dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid, ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine, Mmaf (Monomethyl Auristatin F), C39H65N5O8, (2S)-2-[(2R)-2-[(R)-[(2S)-1-[(3R,4S,5S)-4-[(2S)-N,3-dimethyl-2-[(2S)-3-methyl-2-(methylamino)butanamido]butanamido]-3-methoxy-5-methylheptanoyl]pyrrolidin-2-yl](methoxy)methyl]propanamido]-3-phenylpropanoic acid, N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(aR,ssR,2S)-ss-methoxy-a-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; MMAF;, MonomethylauristatinF, SCHEMBL3208014, CHEMBL3359822, MonoMethyl auristatin F (MMAF), GLXC-90472, EX-A1046, HY-15579G, AKOS027326749, FM76372, AC-30596, BP-22316, HY-15579, SY034480, DB-094829, CS-0899298, (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methyl-propanoyl]amino]-3-phenyl-propanoic acid, L-PHENYLALANINE, N-METHYL-L-VALYL-L-VALYL-(3R,4S,5S)-3-METHOXY-5-METHYL-4-(METHYLAMINO)HEPTANOYL-(.ALPHA.R,.BETA.R,2S)-.BETA.-METHOXY-.ALPHA.-METHYL-2-PYRROLIDINEPROPANOYL-
Theoretical properties:
molecular_formula: C39H65N5O8
molecular_weight: 732.0 g/mol
exact_mass: 731.48331405 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 9
rotatable_bond_count: 21
heavy_atom_count: 52
topological_polar_surface_area: 167 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Marble Mountain Air Facility (MMAF), also known as Da Nang East Airfield, Marble Mountain Army Airfield and Nuoc Man Airfield, was an aviation facility used primarily by the United States Marine Corps during the Vietnam War. It was a helicopter facility that was constructed in August 1965 and served as home to Marine Aircraft Group 16 (MAG-16), the 5th Special Forces Group and an assortment of other squadrons until May 1971. It was controlled by the United States Army from May 1971 to August 1972 and finally by the Republic of Vietnam Air Force (RVNAF) from 29 August 1972 to 29 March 1975 when it fell to the People's Army of Vietnam (PAVN). It was in Quảng Nam Province 5 miles (8 km) southeast of Da Nang Air Base on a strip of beach between China Beach and the Marble Mountains.