Compound: DIETHYLPROPION
SMILES: O=C(c1ccccc1)C(N(CC)CC)C
InChIKey: XXEPPPIWZFICOJ-UHFFFAOYSA-N
Synonyms: DIETHYLPROPION, Amfepramone, Diethylpropione, Amfepramon, Amphepramone, Nopropiophenone, Adiposon, Amphepramon, Frekentine, Danylen, Magrene, Tylinal, Diethylcathinone, 90-84-6, alpha-Benzoyltriethylamine, Amfepramonum, Anfepramona, Cegramine, Obesitex, Derfon, Neobes, Silutin, alpha-Diethylaminopropiophenone, 2-(Diethylamino)propiophenone, 1-Propanone, 2-(diethylamino)-1-phenyl-, 2-(Diethylamino)-1-phenyl-1-propanone, 2-(diethylamino)-1-phenylpropan-1-one, 1-Phenyl-2-diethylamino-1-propanone, 2-Diethylaminopropiophenone, Anferpramon, Propiophenone, 2-(diethylamino)-, (+-)-diethylpropion, J4.327C, Q94YYU22B8, C06954, D07444, CHEBI:4530, DTXSID6022929, Phepranon, Dietilretard, Dietil retard, Dietil-retard, Norex, Ifa, RefChem:56557, DTXCID202929, 202-019-1, Tepanil, Amfepramone [INN], Amfepramonum [INN-Latin], Anfepramona [INN-Spanish], Regenon, DEA No. 1610, Amfepramone (INN), Regenon hydrochloride, .alpha.-benzoyltriethylamine, Anfamon, Keramik, Keramin, Modulor, Parabolin, Tenuate hydrochloride, Diethylpropione hydrochloride, UR 1423, Diethylpropion (BAN), Fenyl-(1-diethylaminoethyl)keton [Czech], Fenyl-(1-diethylaminoethyl)keton, HSDB 3059, 2-Diethylaminopropiophenone hydrochloride, NCGC00167475-01, EINECS 202-019-1, BRN 2804400, UNII-Q94YYU22B8, Diethylpropin, 1-Phenyl-2-diethylaminopropanone-1 hydrochloride, Propiophenone, 2-(diethylamino)-, hydrochloride, Propiophenone, 2-diethylamino-, (+/-)-diethylpropion, AMFEPRAMONE [HSDB], DIETHYLPROPION [MI], SCHEMBL27330, AMFEPRAMONE [WHO-DD], 4-14-00-00144 (Beilstein Handbook Reference), DIETHYLPROPION [VANDF], GTPL7161, CHEMBL1194666, AKOS025401369, DB00937, AC-13099, 2-(Diethylamino)-1-phenyl-1-propanone #, NS00008562, 1-Phenyl-2-diethylamino-1-propanone hydrochloride, Q2356505, BRD-A37288617-003-01-4, BRD-A37288617-003-02-2
Theoretical properties:
molecular_formula: C13H19NO
molecular_weight: 205.30 g/mol
exact_mass: 205.146664230 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 5
heavy_atom_count: 15
topological_polar_surface_area: 20.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: White or creamy white, small crystals or crystalline powder; characteristic, mildly aromatic odor; 1 g sol in: about 0.6 mL water, about 0.6 ml chloroform, 1 ml absolute methanol, 1 ml alcohol; practically insoluble in ether /Diethylpropion hydrochloride/
Descriptions:
pubchem: Diethylpropion is an aromatic ketone that is propiophenone in which one of the hydrogens alpha- to the carbonyl is substituted by a diethylamino group. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as the hydrochloride as an anoretic in the short term management of obesity. It has a role as an appetite depressant. It is a tertiary amine and an aromatic ketone. It is functionally related to a propiophenone.
chebi: An  aromatic ketone that is propiophenone in which one of the hydrogens α- to the carbonyl is substituted by a diethylamino group. A central stimulant and indirect-acting sympathomimetic, it is an appetite depressant and is used as the hydrochloride as an anoretic in the short term management of obesity.
chembl: DIETHYLPROPION is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Amfepramone, also known as diethylpropion, is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant. It is used in the short-term management of obesity, along with dietary and lifestyle changes. Amfepramone has a similar chemical structure to the antidepressant and smoking cessation aid bupropion (previously called amfebutamone), which has also been developed as a weight-loss medicine when in a combination product with naltrexone.