Compound: phloretin
SMILES: O=C(c1c(O)cc(O)cc1O)CCc2ccc(O)cc2
InChIKey: VGEREEWJJVICBM-UHFFFAOYSA-N
Synonyms: phloretin, 60-82-2, Dihydronaringenin, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one, Phloretol, 1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, DTXSID6022393, S5J5OE47MK, NSC-407292, DTXCID702393, FEMA NO. 4390, CHEBI:17276, 2',4,4',6'-Tetrahydroxydihydrochalcone, 2',4,4',6'-Tetrahydroxy-Dihydrochalcone, RefChem:861869, 200-488-7, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone, MFCD00002288, NSC 407292, beta-(p-Hydroxyphenyl)phloropropiophenone, 2',4',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone, 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)-propiophenone, NSC407292, beta-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 4,2',4',6'-Tetrahydroxydihydrochalcone, beta-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, CHEMBL45068, 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone, Propiophenone, 2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-, .beta.-(p-Hydroxyphenyl)phloropropiophenone, NSC 407292;RJC 02792, SMR000326783, CCRIS 7459, SR-01000076081, EINECS 200-488-7, UNII-S5J5OE47MK, Asebogenol;, Dihydronarigenin;, 2uxi, G50, Icaritin Impurity 7, Phloretin (Standard), Spectrum_001295, Phloretin, >=99%, SpecPlus_000333, PHLORETIN [MI], Spectrum2_000681, Spectrum3_001036, Spectrum4_001172, Spectrum5_001698, Lopac-P-7912, cid_4788, Lopac0_001012, Oprea1_824722, REGID_for_CID_4788, SCHEMBL38131, BSPBio_002851, KBioGR_001803, KBioSS_001775, SPECTRUM300554, MLS000728507, MLS000859922, MLS006012024, BIDD:ER0174, DivK1c_006429, SPBio_000801, GTPL4285, orb1304838, orb3139905, BCBcMAP01_000040, BDBM23446, HY-N0142R, KBio1_001373, KBio2_001775, KBio2_004343, KBio2_006911, KBio3_002071, Phloretin - CAS 60-82-2, BP_35, HMS2224N17, HMS3263K05, HMS3332J03, HMS3656I07, HY-N0142, TNP00255, Tox21_202854, Tox21_501012, CCG-38573, HB0500, LMPK12120525, MSK000821, s2342, SBB066137, STL372996, AKOS015856338, AC-7995, CS-1477, DB07810, EBC-458049, FP06961, LP01012, SDCCGMLS-0066637.P001, SDCCGSBI-0050985.P003, CAS-60-82-2, Phloretin, analytical reference material, SMP1_000238, NCGC00015840-01, NCGC00015840-02, NCGC00015840-03, NCGC00015840-04, NCGC00015840-05, NCGC00015840-06, NCGC00015840-07, NCGC00015840-08, NCGC00015840-09, NCGC00015840-18, NCGC00094304-01, NCGC00094304-02, NCGC00094304-03, NCGC00094304-04, NCGC00260400-01, NCGC00261697-01, AS-14100, ST057164, SY017103, DB-053714, EU-0101012, NS00006825, P1966, SW219308-1, C00774, P 7912, F002612, ?-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 2',6'-Trihydroxy-3-(p-hydroxyphenyl)propiophenone, 2,4,6-Trihydroxy-3-(4-hydroxyphenyl)propiophenone, Q2268463, SR-01000076081-1, SR-01000076081-7, SR-01000076081-8, .beta.-(p-Hydroxyphenyl)-2,6-trihydroxypropiophenone, BRD-K15563106-001-02-4, BRD-K15563106-001-10-7, BRD-K15563106-001-18-0, Propiophenone,4',6'-trihydroxy-3-(p-hydroxyphenyl)-, .beta.-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 1-(2,4,6-trihydroxyphenyl)-3-(4-hydroxyphenyl)-1-propanone, 3-(4-Hydroxy-phenyl)-1-(2,4,6-trihydroxy-phenyl)-propan-1-one, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphen  yl)-1-propanone, 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)-PROPAN-1-ONE [FHFI], InChI=1/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H
Theoretical properties:
molecular_formula: C15H14O5
molecular_weight: 274.27 g/mol
exact_mass: 274.08412354 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 4
heavy_atom_count: 20
topological_polar_surface_area: 98 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 263.5 °C
solubility: 0.123 mg/mL at 16 °C
Descriptions:
pubchem: Phloretin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'. It has a role as an antineoplastic agent and a plant metabolite. It is functionally related to a dihydrochalcone.
chebi: A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.
chembl: PHLORETIN is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Phloretin is a dihydrochalcone, a type of natural phenol.  It can be found in apple tree leaves and the Manchurian apricot.