Compound: methoxamine
SMILES: O(c1c(cc(OC)cc1)C(O)C(N)C)C
InChIKey: WJAJPNHVVFWKKL-UHFFFAOYSA-N
Synonyms: methoxamine, Methoxamin, 390-28-3, 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol, Methoxamedrine, Pseudomethoxamine, Metossamina, CHEBI:6839, Benzenemethanol, alpha-(1-aminoethyl)-2,5-dimethoxy-, NRL001, DTXSID0023290, NRL-001, Methoxamedrin, Vasoxin, Wellcome, Metoxamine, RefChem:811759, DTXCID403290, 206-867-3, HUQ1KC1YLI, 2,5-Dimethoxynorephedrine, Metoxamina, CHEMBL524, alpha-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol, Benzenemethanol, .alpha.-(1-aminoethyl)-2,5-dimethoxy-, Benzyl alcohol, .alpha.-(1-aminoethyl)-2,5-dimethoxy-, Methoxamine (BAN), Benzyl alcohol, alpha-(1-aminoethyl)-2,5-dimethoxy-, Spectrum_001021, Prestwick0_000535, Prestwick1_000535, Prestwick2_000535, Prestwick3_000535, Spectrum2_000776, Spectrum3_000498, Spectrum4_000051, Spectrum5_001821, Epitope ID:613447, Lopac0_000769, SCHEMBL34158, BSPBio_000549, BSPBio_001995, GTPL483, KBioGR_000541, KBioSS_001501, 2-amino-1-[2,5-bis(methyloxy)phenyl]propan-1-ol, SPBio_000852, SPBio_002470, BPBio1_000605, SCHEMBL29763696, KBio2_001501, KBio2_004069, KBio2_006637, KBio3_001495, BDBM50026777, EBC-26210, MFCD00242998, SBB094499, AKOS009208855, CCG-204854, DB00723, SDCCGSBI-0050747.P004, NCGC00015692-03, NCGC00015692-04, NCGC00015692-06, NCGC00015692-08, NCGC00015692-13, NCGC00089793-02, SBI-0050747.P003, AB00053731, NS00007655, C07513, D08201, EN300-365687, 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol, 2-Amino-1-(2,5-dimethoxyphenyl)-1-propanol #, AB00053731_12, AB00053731_13, L000757, Q685119, BRD-A39189014-003-14-4, BRD-A39189014-003-21-9, BRD-A39189014-003-22-7, (.+/-.)-.alpha.-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol, 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol (methoxamine), 2-Amino-1-(2,5-dimethoxy-phenyl)-propan-1-ol(Methoxamine)
Theoretical properties:
molecular_formula: C11H17NO3
molecular_weight: 211.26 g/mol
exact_mass: 211.12084340 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 4
heavy_atom_count: 15
topological_polar_surface_area: 64.7 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: Soluble (185 g/L)
Descriptions:
pubchem: Methoxamine is an amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at alpha-adrenoceptors with selectivity for the alpha-1 adrenoceptor subtype similar to phenylephrine. It has a role as an antihypotensive agent and an alpha-adrenergic agonist.
chebi: An amphetamine in which the parent 1-phenylpropan-2-amine skeleton is substituted at position 1 with an hydroxy group and the phenyl ring is 2- and 5-substituted with methoxy groups. It is an antihypotensive agent (pressor), an agonist acting directly at α-adrenoceptors with selectivity for the α-1 adrenoceptor subtype similar to phenylephrine .
chembl: METHOXAMINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Methoxamine, sold under the brand names Vasoxine, Vasoxyl, and Vasylox among others, is a sympathomimetic medication used as an antihypotensive agent. It has mostly or entirely been discontinued.
The drug is an α1-adrenergic receptor agonist.