Compound: sepiapterin
SMILES: O=c1nc([nH]c2c1N=C(C(=O)[C@@H](O)C)CN2)N
InChIKey: VPVOXUSPXFPWBN-VKHMYHEASA-N
Synonyms: sepiapterin, L-Sepiapterin, 17094-01-8, Sepiapterine, CNSA-001, PTC923, PTC-923, CJQ26KO7HP, 2-Amino-6-(S)-lactoyl-7,8-dihydro-4(3H)-pteridinone, DTXSID40937902, 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-3H-pteridin-4-one, 4(3H)-pteridinone, 2-amino-7,8-dihydro-6-((2S)-2-hydroxy-1-oxopropyl)-, sepia-pterin, 2-amino-6-[(2S)-2-hydroxypropanoyl]-1,4,7,8-tetrahydropteridin-4-one, CHEBI:16095, 2-amino-6-((2S)-2-hydroxypropanoyl)-1,4,7,8-tetrahydropteridin-4-one, 2-amino-6-((2S)-2-hydroxypropanoyl)-7,8-dihydro-3H-pteridin-4-one, 4(3H)-Pteridinone, 2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-, RefChem:182421, DTXCID301476590, 2-amino-7,8-dihydro-6-((2S)-2-hydroxy-1-oxopropyl)-4(3H)-pteridinone acid, SEPHIENCE, Sepiapterin [USAN], (S)-2-Amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one, Lopac-S-154, 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydropteridin-4(1H)-one, UNII-CJQ26KO7HP, Sepiapterina, 4(3H)-Pteridinone,2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-, Sephience (TN), Sepiapterin, solid, SEPIAPTERIN [INN], 2-amino-6-[(2S)-2-hydroxypropanoyl]-7,8-dihydro-1H-pteridin-4-one, Sepiapterin (L-Sepiapterin), Lopac0_001123, 6-lactoyl-7,8-dihydropterin, MLS002153268, SCHEMBL258399, Sepiapterin (JAN/USAN/INN), orb1692176, SCHEMBL7943016, CHEMBL1255653, GTPL14278, CHEBI:194527, GLXC-27903, HMS2234O10, HMS3263B07, Tox21_501123, WHO 11848, AKOS022181294, CCG-205198, FS11305, LP01123, SDCCGSBI-0051091.P002, NCGC00015913-01, NCGC00094391-01, NCGC00094391-02, NCGC00094391-03, NCGC00094391-05, NCGC00261808-01, SMR001230707, HY-112234, CS-0044215, EU-0101123, S-154, ST50405213, C00835, D12286, G12478, SR-01000075522, Q2271580, SR-01000075522-1, 2-Amino-7,8-dihydro-6-(2S-hydroxy-1-oxopropyl)-4(1H)-pteridinone, 6-((2S)-2-hydroxypropanoyl)-2-amino-3,7,8-trihydropteridin-4-one, (S)-2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-Pteridinone, 1-(2-amino-7,8-dihydro-4-hydroxy-6-pteridinyl)-2-hydroxy-1-Propanone, 2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-4(1H)Pteridinone, S(-)-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridione, 2-AMINO-7,8-DIHYDRO-6-((2S)-2-HYDROXY-1-OXOPROPYL)-4(3H)-PTERIDINONE, 4(1H)-Pteridinone, 2-amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-, (S)-
Theoretical properties:
molecular_formula: C9H11N5O3
molecular_weight: 237.22 g/mol
exact_mass: 237.08618923 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 2
heavy_atom_count: 17
topological_polar_surface_area: 129 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: L-sepiapterin is a sepiapterin with L configuration.
chebi: A sepiapterin with <small>L</small> configuration.
chembl: SEPIAPTERIN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Sepiapterin, sold under the brand name Sephience, is a medication used for the treatment of hyperphenylalaninemia. Sepiapterin is a phenylalanine hydroxylase activator. It is also metabolite that is naturally synthesized in the human body.
The most common side effects are upper respiratory tract infection, headache, diarrhea, abdominal pain, hyperphenylalaninemia and discoloration of feces.