Compound: PREGNENOLONE ACETATE
SMILES: O=C(O[C@@H]1CC2=CC[C@H]3[C@H]4[C@]([C@@H](C(=O)C)CC4)(C)CC[C@@H]3[C@@]2(C)CC1)C
InChIKey: CRRKVZVYZQXICQ-RJJCNJEVSA-N
Synonyms: PREGNENOLONE ACETATE, 1778-02-5, 0G0WWV404B, EINECS 217-212-6, 3beta-Hydroxypregn-5-en-20-one acetate, PREGNENOLONE ACETATE [MI], NSC 64827, NSC-64827, PREGNENOLONE ACETATE [WHO-DD], (1S,3aS,3bS,7S,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl acetate, (1S,3aS,3bS,7S,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta(a)phenanthren-7-yl acetate, RefChem:868472, PREGNENOLONE ACETATE [INCI], 217-212-6, MFCD00003627, Antofin, Pregn-5-en-20-one, 3-(acetyloxy)-, (3beta)-, 5-Pregnen-3beta-ol-20-one acetate, Artivis, Enescorb, Previsone, MLS000069411, DTXSID3048942, 3beta-Acetoxy-5-pregnene-20-one, (3S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate, Sharmone, [(3S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate, PREGN-5-EN-20-ONE, 3-(ACETYLOXY)-, (3| cent)-, Pregenolone acetate, Pregnenolone-3-acetate, Pregn-5-en-20-one, 3.beta.-hydroxy-, acetate, Pregn-5-en-20-one, 3-(acetyloxy)-, (3.beta.)-, UNII-0G0WWV404B, NCGC00160652-02, Pregn-5-en-20-one, 3-(acetyloxy)-, (3b)-, Antofin; Artivis; Enescorb; NSC 64827, 5-Pregnenolone acetate, Pregnenolone acetate, 99%, SCHEMBL670746, 3b-Acetoxy-5-pregnen-20-one, CHEMBL1892286, DTXCID6028868, 3b-Acetoxy-?5-pregnen-20-one, CHEBI:34930, HMS2231P18, 3beta-acetoxy-pregn-5-en-20-one, Tox21_113360, 20-Oxopregn-5-en-3beta-yl acetate, 3.beta.-Acetoxypregn-5-en-20-one, AKOS015895364, DB14626, FP27155, 20-Oxopregn-5-en-3.beta.-yl acetate, 5-Pregnen-3.beta.-ol-20-one acetate, SMP1_000246, 5-Pregnen-3-.beta.-ol-20-one acetate, NCGC00166271-02, SMR000059127, SY057216, CAS-1778-02-5, (3b)-3-(Acetyloxy)-pregn-5-en-20-one, 5-Allopregnene-3.beta.-ol-20-one acetate, P0477, D78395, Pregn-5-en-20-one, 3-(acetyloxy)-, (3)-, 20-Oxopregn-5-en-3-yl acetate, (3.beta.)- #, F980128, doi:10.14272/CRRKVZVYZQXICQ-RJJCNJEVSA-N.1, Q27116324
Theoretical properties:
molecular_formula: C23H34O3
molecular_weight: 358.5 g/mol
exact_mass: 358.25079494 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 3
heavy_atom_count: 26
topological_polar_surface_area: 43.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Pregnenolone acetate is a steroid ester.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It has been reported to reduce wrinkles in elderly women when applied in the form of a 0.5% topical cream, effects which were suggested to be due to improved hydration of the skin. Pregnenolone acetate has been marketed in France in a topical cream containing 1% pregnenolone acetate and 10% "sex hormone" for the treatment of premature skin aging but was withdrawn from the market in 1992. Although the medication has been described by some sources as a glucocorticoid, other authors have stated that systemic pregnenolone acetate has no undesirable metabolic or toxic effects even at high doses.