Compound: Etonitazene
SMILES: O=[N+]([O-])c1cc2nc(Cc3ccc(OCC)cc3)n(c2cc1)CCN(CC)CC
InChIKey: PXDBZSCGSQSKST-UHFFFAOYSA-N
Synonyms: Etonitazene, Etonitazine, Etonitazeno, Ciba 20-684BA, ARC 1G2, 911-65-9, Etonitazenum, NIH 7607, Etobedolum, Ba-20684, DTXSID6048919, Acscn-9624, NIH-7607, IDS-NE-006, 9U3GT3353T, 1H-Benzimidazole-1-ethanamine, 2-((4-ethoxyphenyl)methyl)-N,N-diethyl-5-nitro-, DTXCID3028845, etonitazin, 1H-Benzimidazole-1-ethanamine, 2-[(4-ethoxyphenyl)methyl]-N,N-diethyl-5-nitro-, 2-[2-[(4-ethoxyphenyl)methyl]-5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine, 2-(2-((4-ethoxyphenyl)methyl)-5-nitrobenzimidazol-1-yl)-N,N-diethylethanamine, RefChem:139278, (2-(2-((4-ethoxyphenyl)methyl)-5-nitro-1H-1,3-benzodiazol-1-yl)ethyl)diethylamine, 213-009-1, Ba 20684, CHEMBL312040, 1-(2-Diethylaminoethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole, CHEBI:234361, 1-(2-(Diethylamino)ethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole, Etonitazene (INN), Etonitazinum, ETONITAZENE [INN], {2-[2-(4-Ethoxy-benzyl)-5-nitro-benzoimidazol-1-yl]-ethyl}-diethyl-amine, Benzimidazole, 1-[2-(diethylamino)ethyl]-2-(p-ethoxybenzyl)-5-nitro-, BENZIMIDAZOLE, 1-(2-(DIETHYLAMINO)ETHYL)-2-(p-ETHOXYBENZYL)-5-NITRO-, Etonitazenum [INN-Latin], Etonitazeno [INN-Spanish], Etonitazene [INN:BAN:DCF], NSC172231, EINECS 213-009-1, BRN 0363324, UNII-9U3GT3353T, DEA No. 9624, ETONITAZENE [MI], Epitope ID:2278938, SCHEMBL25183, ETONITAZENE [WHO-DD], 5-23-12-00348 (Beilstein Handbook Reference), GTPL1624, SCHEMBL29388421, Tox21_112830, BDBM50013847, PDSP1_001558, PDSP2_001542, 2-[(4-Ethoxyphenyl)methyl]-N,N-diethyl-5-nitro-1H-benzimidazole-1-ethanamine, CS-6622, DB01462, CAS-911-65-9, HY-101645, NS00039388, D12669, L000697, Q5404835, 1-(2-diethylaminoethyl)-2-p-ethoxybenzyl-5-nitrobenzimidazole, 1-(beta-diethylaminoethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole, 2-[2-(4-Ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl]-N,N-diethylethanamine, N-[2-[2-(4-ethoxybenzyl)-5-nitrobenzimidazol-1-yl]ethyl]diethylamine, 2-[2-(4-Ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl]-N,N-diethylethanamine #, 2-[2-[(4-ethoxyphenyl)methyl]-5-nitro-benzimidazol-1-yl]-N,N-diethyl-ethanamine, 2-{2-[(4-Ethoxyphenyl)methyl]-5-nitro-1H-1,3-benzimidazol-1-yl}-N,N-diethylethan-1-amine, 2-{2-[(4-Ethoxyphenyl)methyl]-5-nitro-1H-benzimidazol-1-yl}-N,N-diethylethan-1-amine
Theoretical properties:
molecular_formula: C22H28N4O3
molecular_weight: 396.5 g/mol
exact_mass: 396.21614077 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 9
heavy_atom_count: 29
topological_polar_surface_area: 76.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Etonitazene is a member of the class of benzimidazoles that is 1H-benzimidazole substituted by 2-(diethylamino)ethyl, 4-ethoxybenzyl, and nitro groups at positions 1, 2, and 5, respectively. It is a synthetic opioid. It has a role as an opioid analgesic and a mu-opioid receptor agonist. It is a member of benzimidazoles, an aromatic ether, a C-nitro compound and a tertiary amino compound.
chebi: A member of the class of benzimidazoles that is 1<em>H</em>-benzimidazole substituted by 2-(diethylamino)ethyl, 4-ethoxybenzyl, and nitro groups at positions 1, 2, and 5, respectively. It is a synthetic opioid.
chembl: ETONITAZENE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Etonitazene, also known as EA-4941 or CS-4640, is a benzimidazole opioid, first reported in 1957, that has been shown to have approximately 1,000 to 1,500 times the potency of morphine in animals.
Because it is characterized by a strong dependency potential and a tendency to produce profound respiratory depression, it is not used in humans. It is, however, useful in animal models for addiction studies, particularly those requiring the animals to drink or ingest the agent, because it is not as bitter as opiate salts like morphine sulfate.