Compound: dropropizine
SMILES: OC(CO)CN1CCN(c2ccccc2)CC1
InChIKey: PTVWPYVOOKLBCG-UHFFFAOYSA-N
Synonyms: dropropizine, 17692-31-8, 3-(4-phenylpiperazin-1-yl)propane-1,2-diol, Dipropizine, Catabex, Katril, Ditustat, Tussilex, Larylin, Ribex, Dopropizin, (+-)-Dropropizine, Dropropizina, 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, Dropropizinum, 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol, UCB-1967, UCB 1967, U0K8WHL37U, NSC-757820, DTXSID0045624, U.C.B.-1967, DTXCID8025624, DF-526, RefChem:920663, R05DB19, 241-683-7, (+/-)-DROPROPIZINE, rac Dropropizine, MFCD00079124, Dropropizine (R,S), MLS000069616, NCGC00018230-03, SMR000058256, 3-(4-phenylpiperazinyl)propane-1,2-diol, (+/-)-Dropropizine;UCB-196, Dropropizinum [INN-Latin], Dropropizina [INN-Spanish], Dropropizine [INN:BAN:DCF], CCRIS 3154, SR-01000000154, EINECS 241-683-7, UNII-U0K8WHL37U, U.C.B. 1967, Dropropizin, Prestwick_670, Catabex (TN), (R,S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol, CAS-17692-31-8, 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (R,S)-, Spectrum_000327, Dropropizine (Standard), ( inverted exclamation markA)-Dropropizine, (2R)-3-(4-phenyl-1-piperazinyl)propane-1,2-diol, Opera_ID_1163, Prestwick0_000245, Prestwick1_000245, Prestwick2_000245, Prestwick3_000245, Spectrum2_000965, Spectrum3_001428, Spectrum4_000409, Spectrum5_001538, Dropropizine (INN/BAN), DROPROPIZINE [MI], GlyTouCan:G06114UZ, DROPROPIZINE [INN], Levodropropizine Impurity 12, SCHEMBL93975, ()-Dropropizine;UCB-196, BSPBio_000030, BSPBio_003136, DROPROPIZINE [MART.], KBioGR_000678, KBioSS_000807, MLS001146968, DivK1c_000205, DROPROPIZINE [WHO-DD], SPECTRUM1501004, SPBio_000969, SPBio_002249, BPBio1_000034, CHEMBL151445, orb1310600, SCHEMBL10973337, CHEBI:93837, HMS500K07, HY-B1032R, KBio1_000205, KBio2_000807, KBio2_003375, KBio2_005943, KBio3_002356, 98% NMR, NINDS_000205, GLXC-07797, HMS1568B12, HMS1921B07, HMS2095B12, HMS2235E23, HMS3371B05, HMS3652G20, HMS3652O18, HMS3712B12, HMS5082I18, HMS5082O18, Pharmakon1600-01501004, G06114UZ, HY-B1032, Tox21_110842, CCG-40182, EBC-03703, NSC757820, s4138, SBB015067, (invertedexclamationmarkA)-Dropropizine, AKOS015907632, Tox21_110842_1, CS-4550, DB13785, NSC 757820, IDI1_000205, NCGC00018230-02, NCGC00018230-04, NCGC00018230-05, NCGC00018230-09, NCGC00018230-10, NCGC00089808-02, NCGC00089808-03, NCGC00089808-04, AC-22549, AS-13348, FP180030, ST075184, SY102088, ( inverted exclamation mark_)-Dropropizine, SBI-0051630.P002, DB-011530, DB-057773, AB00052193, NS00000610, SW196825-3, 3-(4-phenyl-1-piperazinyl)propane-1,2-diol, D07393, F14929, AB00052193_16, AB00052193_17, EN300-1705959, Q910111, SR-01000000154-3, SR-01000000154-4, BRD-A29349577-001-05-7, BRD-A29349577-001-15-6, BRD-A29349577-001-22-2, BRD-A29349577-001-23-0, BRD-A29349577-001-24-8, Z31370892, (+/-)-Dropropizine, analytical standard, for drug analysis
Theoretical properties:
molecular_formula: C13H20N2O2
molecular_weight: 236.31 g/mol
exact_mass: 236.152477885 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 4
heavy_atom_count: 17
topological_polar_surface_area: 46.9 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: >35.4 [ug/mL] (The mean of the results at pH 7.4)
Descriptions:
pubchem: 3-(4-phenyl-1-piperazinyl)propane-1,2-diol is a member of piperazines.
chembl: DROPROPIZINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Dropropizine (or dipropizine) is a cough suppressant that is sold in Germany, Central America, South America, and some African countries such as Congo. It is sold as suppositories, tablets, and syrup. It is used to stop a cough caused by allergies or a cold.