Compound: Caramiphen
SMILES: O=C(OCCN(CC)CC)C1(c2ccccc2)CCCC1
InChIKey: OFAIGZWCDGNZGT-UHFFFAOYSA-N
Synonyms: Caramiphen, 77-22-5, Caramiphene, 2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate, Caramiphenum, Caramifeno, 97J7NP0XJY, 1-Phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester, DTXSID0022729, RefChem:918009, DTXCID802729, 1-phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester, 201-013-6, Parpanil, 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate, Pentaphen (pharmaceutical), CYCLOPENTANECARBOXYLIC ACID, 1-PHENYL-, 2-(DIETHYLAMINO)ETHYL ESTER, CHEMBL61946, 2-Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate, Caramifenio, Caramiphen [INN:BAN], MLS000532799, Caramiphene [INN-French], Caramiphenum [INN-Latin], Caramifenio [INN-Spanish], SMR000140237, EINECS 201-013-6, UNII-97J7NP0XJY, BRN 2144901, diethylaminoethyl 1-phenylcyclopentane-1-carboxylate, 2-Diethylaminoethyl 1-phenylcyclopentancarboxylat, 2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate hydrochloride, Caramiphen (free base), CARAMIPHEN [MI], Pentoxyverine impurity B, CARAMIPHEN [INN], CARAMIPHEN [VANDF], CARAMIPHEN [WHO-DD], Pentoxyverine impurity B CRS, cid_67173, SCHEMBL181285, orb1703633, BDBM73402, CHEBI:135204, 1-(2-DIETHYLAMINOETHOXYCARBONYL)-1-PHENYLCYCLOPENTANE, Cyclopentanecarboxylicacid, 1-phenyl-, 2-(diethylamino)ethyl ester, EBC-07616, MFCD00063432, PDSP1_000069, PDSP2_000069, STK179630, AKOS001662910, DB11504, NCGC00167426-02, NS00002057, SBI-0653890.0001, AB00088177-01, AB00088177-10, EN300-23519761, Q5037673, BRD-K59895502-001-01-9, 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate #, 2-Dimethylaminoethyl 1-phenylcyclopentane-1-carboxylate, Caramiphen; Pentoxyverine Hydrogen Citrate EP Impurity B, Pentoxyverine EP Impurity BDiscontinued,See C4X-22708, Z252849348, 1-Phenyl-cyclopentanecarboxylic acid 2-diethylamino-ethyl ester, 1-phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride, 1-phenyl-1-cyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride, Parpanil,Caramiphen (6CI), Pentaphen (pharmaceutical), Pentoxyverine EP impurity B, Caraminphen, Imp. B (EP): 2-(Diethylamino)ethyl 1-Phenyl-cyclopentanecarboxylate (Caramiphen)
Theoretical properties:
molecular_formula: C18H27NO2
molecular_weight: 289.4 g/mol
exact_mass: 289.204179104 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 8
heavy_atom_count: 21
topological_polar_surface_area: 29.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Caramiphen is a member of benzenes.
chembl: CARAMIPHEN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Caramiphen is an anticholinergic drug used in the treatment of Parkinson's disease.  In combination with phenylpropanolamine it is used as a cough suppressant and nasal decongestant to treat symptoms associated with respiratory illnesses such as cold, allergies, hay fever, and sinusitis. It was added to the British National Formulary in 1963, with a dosage of 10 to 20 mg. Side effects include nausea, dizziness, and drowsiness.
It binds to the sigma-1 receptor with an IC50 value of 25 nM.