Compound: Pholedrine
SMILES: Oc1ccc(CC(NC)C)cc1
InChIKey: SBUQZKJEOOQSBV-UHFFFAOYSA-N
Synonyms: Pholedrine, Pulsotyl, Isodrine, Pressitan, 370-14-9, Racemic pholedrine, Pholedrinum, 4-Hydroxy-N-methylamphetamine, p-(2-Methylaminopropyl)phenol, Isodrin (sympathomimetic), Oh-ma, 1-(p-Hydroxyphenyl)-2-methylaminopropane, p-Hydroxy-N-methylamphetamine, Foledrina, p-Hydroxy-N,alpha-dimethylphenethylamine, beta-(p-Hydroxyphenyl)isopropylmethylamine, KNOLL-H75, PHENOL, p-(2-(METHYLAMINO)PROPYL)-, AY28O44JGD, alpha-(p-Hydroxyphenyl)-beta-methylaminopropane, Phenol, p-[2-(methylamino)propyl]-, (+-)-Pholedrine, RefChem:861876, 206-725-0, Veritol, 4-[2-(Methylamino)propyl]phenol, Epifen, P-HYDROXYMETHAMPHETAMINE, Sympropamin, Foledrin, Isodrinum, Pholetone, Stimatone, Syncordan, Terapinyl, Varitol, Veritain, Knoll H75, 4-Hydroxymethamphetamine, Promethin, Prometin, N-Methylparedrine, rac Pholedrine, 4-(2-(Methylamino)propyl)phenol, p-Hydroxy-N-methylbenzedrine, (+/-)-Pholedrine, Phenethylamine, p-hydroxy-N,alpha-dimethyl-, alpha-(p-Oxyphenyl)-beta-methyl aminopropane, 1-(p-Oxyphenyl)-2-methylaminopropan, Pholedrine (INN), Phenol, 4-(2-(methylamino)propyl)-, Phenol, 4-[2-(methylamino)propyl]-, p-Hydroxy-N,.alpha.-dimethylphenethylamine, PHOLEDRINE [INN], .beta.-(p-Hydroxyphenyl)isopropylmethylamine, .alpha.-(p-Hydroxyphenyl)-.beta.-methylaminopropane, (+/-)-1-(4-Hydroxyphenyl)-N-methyl-2-aminopropane, Foledrinio, Pholedrinum [INN-Latin], Foledrinio [INN-Spanish], Pholedrine [INN:BAN:DCF], rac Pholedrine (1.0mg/ml in Acetonitrile), EINECS 206-725-0, 4-hydroxy-N-methylamphetamine; 4-HMA; rac Pholedrine, UNII-AY28O44JGD, Pholedrin, p-[2-(Methylamino)propyl]phenol, 1-(p-Oxyphenyl)-2-methylaminopropan [German], beta(p-Oxy-phenyl)isopropylmethylamin [German], beta(p-Oxy-phenyl)isopropylmethylamin, PHOLEDRINE [MI], PHOLEDRINE [WHO-DD], SCHEMBL119262, CHEMBL2008672, DTXSID70861908, p-[(2-Methylamino)propyl]phenol, CHEBI:134798, Isodrin (sympathomimetic compound), p-[2-(methylamino)propyl]-phenol, p-Hydroxy-N,a-dimethylphenethylamine, AKOS005216720, AKOS017390993, FR27568, NCI60_042163, P-HYDROXYMETHAMPHETAMINE, (+/-)-, DB-049052, CS-0082854, NS00007149, alpha-(p-hydroxyphenyl-beta-methylaminopropane, D08370, Phenethylamine, p-hydroxy-N,.alpha.-dimethyl-, p-Hydroxymethamphetamine, 1.0 mg/mL in methanol, .alpha.-(p-Oxyphenyl)-.beta.-methyl aminopropane, SR-01000944930, Q7187065, SR-01000944930-1, p-Hydroxymethamphetamine, analytical standard, for drug analysis
Theoretical properties:
molecular_formula: C10H15NO
molecular_weight: 165.23 g/mol
exact_mass: 165.115364102 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 3
heavy_atom_count: 12
topological_polar_surface_area: 32.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Pholedrine is a member of amphetamines.
chembl: PHOLEDRINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Pholedrine, also known as 4-hydroxy-N-methylamphetamine and sold under the brand names Paredrinol, Pulsotyl, and Veritol among others, is a sympathomimetic drug used in topical eye drops to dilate the pupil. It can be used to diagnose Horner's syndrome.
In 2004, it remained marketed only in Germany.