Compound: DEXTROMORAMIDE
SMILES: O=C(N1CCCC1)C(c2ccccc2)(c3ccccc3)[C@@H](CN4CCOCC4)C
InChIKey: INUNXTSAACVKJS-OAQYLSRUSA-N
Synonyms: DEXTROMORAMIDE, Pyrrolamidol, Pyrrolamidolum, Moramide, Dextromoramida, Dextromoramidum, Linfadol, Palfadonna, Palphium, Troxilan, Alcoid, Jetrium, Narcolo, Yetrium, 357-56-2, SKF 5137, SKF-5137, R 875, 9S4S6CIY83, Racemoramide, (s)-, (+)-2,2-Diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine, Acscn-9613, (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one, IDS-ND-003, DTXSID8022909, (+)-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine, CHEBI:74274, MCP-875, D Moramide, D-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine, R-875, (+)-4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine, 4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine, 1-((3S)-3-methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)pyrrolidine, Pyrrolidine, 1-(3-methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)-, (S)-, D-Moramide, RefChem:132417, DTXCID602909, 206-613-1, Palfium, Dauran, Jetrium R, MCP 875, Destromoramide, (+)-3-methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanone, Destromoramide [DCIT], Dextromoramide [INN:BAN], UNII-9S4S6CIY83, Dextromoramidum [INN-Latin], Dextromoramida [INN-Spanish], Pyrrolidine, 1-(2,2-diphenyl-3-methyl-4-morpholinobutyryl)-, (+)-, EINECS 206-613-1, Dextromoramide (BAN), 3-methyl-4-morpholin-4-yl-2,2-di(phenyl)-1-pyrrolidin-1-ylbutan-1-one, DEXTROMORAMIDE [MI], DEXTROMORAMIDE [INN], SCHEMBL25463, DEXTROMORAMIDE [MART.], DEA No. 9613, DEXTROMORAMIDE [WHO-DD], 4-[2-Methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl]morpholine, (-)-, CHEMBL2365707, Pyrrolidine, 1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)-, (-)-, INUNXTSAACVKJS-OAQYLSRUSA-N, (+)-N-(3-Methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidin, (+)-3-Methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanon, (3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one, DB01529, D07287, Q408446, 1-BUTANONE, 3-METHYL-4-(4-MORPHOLINYL)-2,2-DIPHENYL-1-(1-PYRROLIDINYL)-, (3S)-
Theoretical properties:
molecular_formula: C25H32N2O2
molecular_weight: 392.5 g/mol
exact_mass: 392.246378268 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 6
heavy_atom_count: 29
topological_polar_surface_area: 32.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Dextromoramide is an N-acylpyrrolidine arising by formal condensation of pyrrolidine with (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenylbutanoic acid. An opioid analgesic that is structurally related to methadone, it is more poweful than morphine but shorter acting. It has been used (particularly as the hydrogen tartrate salt) for the treatment of severe pain, but was discontinued in the UK in 2004. It has a role as an opioid analgesic. It is a member of morpholines and a N-acylpyrrolidine.
chebi: An <em>N</em>-acylpyrrolidine arising by formal condensation of pyrrolidine with (3<i>S</i>)-3-methyl-4-(morpholin-4-yl)-2,2-diphenylbutanoic acid. An opioid analgesic that is structurally related to methadone, it is more poweful than morphine but shorter acting. It has been used (particularly as the hydrogen tartrate salt) for the treatment of severe pain, but was discontinued in the UK in 2004.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Dextromoramide (Palfium, Palphium, Jetrium, Dimorlin) is a powerful opioid analgesic approximately three times more potent than morphine but shorter acting. It is subject to drug prohibition regimes, both internationally through UN treaties and by the criminal law of individual nations, and is usually prescribed only in the Netherlands.