Compound: Bolasterone
SMILES: O=C1C=C2[C@]([C@@H]3[C@H]([C@H]4[C@]([C@](O)(C)CC4)(C)CC3)[C@@H](C2)C)(C)CC1
InChIKey: IVFYLRMMHVYGJH-VLOLGRDOSA-N
Synonyms: Bolasterone, 1605-89-6, Bolasterona, 17beta-Hydroxy-7alpha,17-dimethylandrost-4-en-3-one, Bolasteronum, U-19763, NSC-66233, 7alpha,17alpha-Dimethyltestosterone, T7ZM08F7FU, 7alpha,17-Dimethyltestosterone, DTXSID40166896, NSC66233, RefChem:569796, DTXCID2089387, 216-519-2, Myagen, 7.alpha.,17-Dimethyltestosterone, (7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-7,10,13,17-tetramethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one, U 19763, 7.alpha.,17.alpha.-Dimethyltestosterone, NSC 66233, Bolasterone (1.0mg/ml in Acetonitrile), Androst-4-en-3-one, 17-hydroxy-7,17-dimethyl-, (7.alpha.,17.beta.)-, Bolasterone [USAN:INN], Bolasteronum [INN-Latin], UNII-T7ZM08F7FU, Bolasterona [INN-Spanish], Androst-4-en-3-one,17-dimethyl-, EINECS 216-519-2, BOLASTERONE [MI], BOLASTERONE [INN], Bolasterone (USAN/INN), BOLASTERONE [USAN], 17.beta.-Hydroxy-7.alpha.,17-dimethylandrost-4-en-3-one, 17beta-hydroxy-7alpha,17alpha-dimethylandrost-4-en-3-one, 7a,17a-Dimethyltestosterone, BOLASTERONE [MART.], 7a,17-dimethyl-Testosterone, Testosterone, 17beta-hydroxy-7alpha,17-dimethyl-, SCHEMBL145066, CHEMBL259548, CHEBI:34583, BDBM50423546, LMST02020017, Bolasterone (1 mg/ml in Acetonitrile), DB01471, 7-ALPHA-17-DIMETHYLTESTOSTERONE, NS00021718, D03144, U19763, 17b-Hydroxy-7a,17-dimethylandrost-4-en-3-one, 7a,17a-Dimethyl-17b-hydroxyandrost-4-en-3-one, 17b-hydroxy-7a,17-dimethyl-Androst-4-en-3-one, 17b-Hydroxy-7a,17a-dimethylandrost-4-ene-3-one, Q4938950, 4-Androsten-7alpha,17alpha-dimethyl-17beta-ol-3-one, (7a,17b)-17-hydroxy-7,17-dimethyl-Androst-4-en-3-one, 7alpha,17alpha-Dimethyl-17beta-hydroxyandrost-4-en-3-one, Androst-4-en-3-one, 17beta-hydroxy-7alpha,17-dimethyl-, Androst-4-en-3-one,17-dimethyl-, (7.alpha.,17.beta.)-, Androst-4-en-3-one, 17-hydroxy-7,17-dimethyl-, (7alpha,17beta)-
Theoretical properties:
molecular_formula: C21H32O2
molecular_weight: 316.5 g/mol
exact_mass: 316.240230259 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 0
heavy_atom_count: 23
topological_polar_surface_area: 37.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Bolasterone is a 3-hydroxy steroid. It has a role as an androgen.
chembl: BOLASTERONE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Bolasterone (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (brand names Myagen, Methosarb; former developmental code name U-19763), also known as 7α,17α-dimethyltestosterone, is a 17α-alkylated androgen/anabolic steroid (AAS) which is used in veterinary medicine. It has close structural similarity to testosterone, and like methyltestosterone has a methyl group at C17α in order to increase oral bioavailability. In addition, it is also 7α-methylated, similar to its 7β-methylated isomer calusterone. The medication has a low to moderate ratio of anabolic to androgenic activity, similar to that of fluoxymesterone.
Bolasterone is on the World Anti-Doping Agency's list of prohibited substances, and is therefore banned from use in most major sports.