Compound: ERIODICTYOL
SMILES: O=C1c2c(O[C@@H](C1)c3cc(O)c(O)cc3)cc(O)cc2O
InChIKey: SBHXYTNGIZCORC-ZDUSSCGKSA-N
Synonyms: ERIODICTYOL, 552-58-9, Eriodictiol, (+)-Eriodictyol, DTXSID70877706, (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one, Q520486B8Y, CHEBI:28412, NSC-649412, 3',4',5,7-Tetrahydroxyflavanone, RefChem:137633, DTXCID901015774, 209-016-4, (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one, (S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone, MFCD00135890, Eriodictyol - 98%, CHEMBL8996, Huazhongilexone, (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one, (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one, (S)-Eriodictyol, eridioctyol, eriodicryol, eriodyctiol, eryodictiol, UNII-Q520486B8Y, ERD, EINECS 209-016-4, 4'-hydroxynaringenin, NSC 649412, Eriodictyol - 90%, Eriodictyol with HPLC, ERIODICTYOL [MI], GlyTouCan:G69343WQ, SCHEMBL19180, orb1300257, orb3140615, Eriodictyol, analytical standard, SCHEMBL29382523, SCHEMBL29709569, SCHEMBL30468822, 5,7,3'',4''-tetrahydroxyflavon, G69343WQ, HY-N0637, Eriodictyol, >=95.0% (HPLC), BDBM50325671, LMPK12140002, MSK158874, s9123, 5,7,3'',4''-tetrahydroxyflavanone, AKOS025311577, AC-6043, CCG-267356, EBC-431056, FE65017, (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one, (2S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one, (S)-3',4',5,7-Tetrahydroxyflavanone, AS-72316, DA-52977, FE146201, CS-0009666, NS00014833, C05631, EN300-18546823, Q3459685, (2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chroman-4-one, (S)-2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chroman-4-one, (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
Theoretical properties:
molecular_formula: C15H12O6
molecular_weight: 288.25 g/mol
exact_mass: 288.06338810 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 1
heavy_atom_count: 21
topological_polar_surface_area: 107 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 269 - 270 °C
solubility: 0.07 mg/mL at 20 °C
Descriptions:
pubchem: Eriodictyol is a tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' respectively. It is a tetrahydroxyflavanone and a member of 3'-hydroxyflavanones.
chebi: A tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' respectively.
chembl: ERIODICTYOL is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from yerba santa (Eriodictyon californicum), a plant native to North America.  Eriodictyol is one of the four flavanones identified in this plant as having taste-modifying properties, the other three being homoeriodictyol, its sodium salt, and sterubin.
Eriodictyol has garnered scientific attention for its strong antioxidant, anti-inflammatory, and neuroprotective properties. Structurally similar to other flavonoids, such as hesperidin and naringenin, eriodictyol scavenges free radicals and regulates inflammatory responses.
Eriodictyol was also found in the twigs of Millettia duchesnei, in Eupatorium arnottianum, and its glycosides (eriocitrin) in lemons and rose hips (Rosa canina).
Eriodictyol belongs to the flavanone subclass of flavonoids and has a chemical structure defined by the molecular formula C15H12O6, with a molecular weight of 288.25 g/mol.