Compound: lividomycin A
SMILES: O1[C@H](O[C@H]2[C@H](O)[C@@H](N)[C@@H](O[C@H]3[C@@H](O)[C@H](O[C@H]4[C@H](O[C@H]5O[C@@H]([C@@H](O)C[C@H]5N)CO)[C@@H](N)C[C@H]([C@@H]4O)N)O[C@@H]3CO)O[C@H]2CN)[C@@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
InChIKey: DBLVDAUGBTYDFR-SWMBIRFSSA-N
Synonyms: lividomycin A, Lividomycin, Quintomycin B, Mannosyldeoxyparomomycin, 36441-41-5, Lividomicina, Lividomycine, Antibiotic 503-2, Lividomycinum, Antibiotic SF 767 A, SF 767 A, CHEBI:71961, A606AJ494W, DTXSID8023218, (1R,2R,3S,4R,6S)-4,6-diamino-3-hydroxy-2-{[alpha-D-mannopyranosyl-(1->4)-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-beta-D-ribofuranosyl]oxy}cyclohexyl 2-amino-2,3-dideoxy-alpha-D-ribo-hexopyranoside, (2R,3S,4S,5S,6R)-2-[(2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,5S,6R)-3-amino-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-4-hydroxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol, (1R,2R,3S,4R,6S)-4,6-diamino-3-hydroxy-2-((alpha-D-mannopyranosyl-(1->4)-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-beta-D-ribofuranosyl)oxy)cyclohexyl 2-amino-2,3-dideoxy-alpha-D-ribo-hexopyranoside, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-diamino-2-((2S,3R,5S,6R)-3-amino-5-hydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-6-hydroxycyclohexyl)oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl)oxy-4-hydroxyoxan-3-yl)oxy-6-(hydroxymethyl)oxane-3,4,5-triol, RefChem:153823, DTXCID203218, 11111-23-2, O-2-Amino-2,3-dideoxy-alpha-D-ribo-hexopyranosyl-(1-4)-O-(O-alpha-D-mannopyranosyl-(1-4)-O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-beta-D-ribofuranosyl-(1-5))-2-deoxy-D-streptamine, LIV, Livodymycin, Lividomycin [INN:DCF], Lividomycine [INN-French], Lividomycinum [INN-Latin], Lividomicina [INN-Spanish], Lividomycin A sulfate salt, BRN 6763509, UNII-A606AJ494W, LIVIDOMYCIN [INN], SCHEMBL195432, CHEMBL389029, orb1696430, BDBM50534265, HY-N12182, AKOS040752615, DB04728, D-Streptamine, O-2-amino-2,3-dideoxy-alpha-D-ribo-hexopyranosyl-(1-4)-O- (O-alpha-D-mannopyranosyl-(1-4)-O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-beta-D-ribofuranosyl-(1-5))-2-deoxy-, O-2-Amino-2,3-dideoxy-alpha-D-ribo-hexopyranosyl-(1->4)-O-(O-alpha-D-mannopyranosyl-(1->4)-O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1->3)-beta-D-ribofuranosyl-(1->5))-2-deoxy-D-streptamine, CS-0892943, NS00011542, C17707, Q6658885, (2R,3S,4S,5S,6R)-2-(((2S,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2S,3R,5S,6R)-3-amino-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahy, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R, (2R,3S,4S,5S,6R)-2-[(2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,5S,6R)-3-amino-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6-hydroxy-cyclohexoxy]-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-4-hydroxy-tetrahydropyran-3-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol, ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET, D-Streptamine, O-alpha-D-mannopyranosyl-(1-->4)-O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-->3)-O-beta-D-ribofuranosyl-(1-->5)-O-[2-amino-2,3-dideoxy-alpha-D-ribo-hexopyranosyl-(1-->4)]-2-deoxy-, HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, O-2-AMINO-2,3-DIDEOXY-.ALPHA.-D-RIBO-HEXOPYRANOSYL-(1->4)-O-(O-.ALPHA.-D-MANNOPYRANOSYL-(1->4)-O-2,6-DIAMINO-2,6-DIDEOXY-.BETA.-L-IDOPYRANOSYL-(1->3)-.BETA.-D-RIBOFURANOSYL-(1->5))-2-DEOXY-D-STREPTAMINE
Theoretical properties:
molecular_formula: C29H55N5O18
molecular_weight: 761.8 g/mol
exact_mass: 761.35420992 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 15
hydrogen_bond_acceptor_count: 23
rotatable_bond_count: 12
heavy_atom_count: 52
topological_polar_surface_area: 406 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Lividomycin A is a member of the class of lividomycins that is lividomycin B in which position 4 of the diamino-L-idopyranosyl moiety has been converted into its alpha-D-mannopyranoside. It has a role as a metabolite. It is functionally related to a lividomycin B and a paromomycin.
chebi: A member of the class of lividomycins that is lividomycin B in which position 4 of the diamino-<small>L</small>-idopyranosyl moiety has been converted into its α-<small>D</small>-mannopyranoside.
chembl: LIVIDOMYCIN is a oligosaccharide listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Lividomycin is a broad-spectrum aminoglycoside antibiotic. It is effective against most Gram-positive and Gram-negative bacteria including Mycobacterium tuberculosis (the causative agent of tuberculosis) and Pseudomonas aeruginosa.