Compound: Forasartan
SMILES: n1c(-c2c(-c3nn[nH]n3)cccc2)ccc(c1)Cn4nc(CCCC)nc4CCCC
InChIKey: YONOBYIBNBCDSJ-UHFFFAOYSA-N
Synonyms: Forasartan, 145216-43-9, SC-52458, 5-[(3,5-dibutyl-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine, SC 52458, forasartanum, 065F7WPT0B, 5-((3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-ylphenyl))pyridine, CHEBI:141552, DTXSID70162942, Pyridine, 5-((3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-yl)phenyl)-, 5-[(3,5-dibutyl-1h-1,2,4-triazol-1-yl)methyl]-2-[2-(1h-tetrazol-5-yl)phenyl]pyridine, fora-sartan, 5-((3,5-dibutyl-1,2,4-triazol-1-yl)methyl)-2-(2-(2H-tetrazol-5-yl)phenyl)pyridine, 5-((3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-yl)phenyl)pyridine, 5-((dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(2H-1,2,3,4-tetrazol-5-yl)phenyl)pyridine, 5-[(dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]pyridine, RefChem:599620, DTXCID7085433, CHEMBL315021, SC 52458;Pyridine, 5-[(3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(1H-tetrazol-5-yl)phenyl]-, Forasartan (USAN/INN), Forasartan [USAN:INN], UNII-065F7WPT0B, 5-((3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(o-1H-tetrazol-5-ylphenyl)pyridine, 5-[(3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-(O-1H-tetrazol-5-ylphenyl)pyridine, Forasartan [WHO-DD], FORASARTAN [INN], FORASARTAN [USAN], SCHEMBL489497, SCHEMBL489498, GTPL6896, orb1986036, SCHEMBL29416780, BDBM50049209, AKOS040751844, DB01342, FF168409, NS00069953, D04243, L007541, Q8564451, 5-(3,5-Dibutyl-[1,2,4]triazol-1-ylmethyl)-2-[2-(1H-tetrazol-5-yl)-phenyl]-pyridine, 5-(3,5-Dibutyl-[1,2,4]triazol-1-ylmethyl)-2-[2-(2H-tetrazol-5-yl)-phenyl]-pyridine, 5-[(3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine
Theoretical properties:
molecular_formula: C23H28N8
molecular_weight: 416.5 g/mol
exact_mass: 416.24369293 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 10
heavy_atom_count: 31
topological_polar_surface_area: 98.1 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: 6.67e-03 g/L
Descriptions:
pubchem: Forasartan is a member of the class of pyridines that is pyridine which is substituted at positions 2 and 5 by o-(tetrazol-5-yl)phenyl and (3,5-dibutyl-1,2,4-triazol-1-yl)methyl groups, respectively. It is a nonpeptide antagonist of angiotensin II, type 1 (AT1) receptors, used for the treatment of hypertension. It has a role as an antihypertensive agent and an angiotensin receptor antagonist. It is a member of benzenes, a member of pyridines, a member of tetrazoles and a member of triazoles.
chebi: A member of the class of pyridines that is pyridine which is substituted at positions 2 and 5 by <em>o</em>-(tetrazol-5-yl)phenyl and (3,5-dibutyl-1,2,4-triazol-1-yl)methyl groups, respectively. It is a nonpeptide antagonist of angiotensin II, type 1 (AT<small><sub>1</sub></small>) receptors, used for the treatment of hypertension.
chembl: FORASARTAN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Forasartan, otherwise known as the compound SC-52458, is a nonpeptide angiotensin II receptor antagonist (ARB, AT1 receptor blocker).