Compound: Famprofazone
SMILES: O=c1n(n(C)c(c1C(C)C)CN(C(Cc2ccccc2)C)C)-c3ccccc3
InChIKey: GNUXVOXXWGNPIV-UHFFFAOYSA-N
Synonyms: Famprofazone, 22881-35-2, Famprofazonum, Famprofazona, HN0NCX453C, NSC-759244, DTXSID3045435, DTXCID1025435, 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one, 1-methyl-5-((methyl(1-phenylpropan-2-yl)amino)methyl)-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one, RefChem:139922, 4-isopropyl-2-methyl-3-(N-methyl-N-(alpha-methylphenylethyl)aminomethyl)-1-phenyl-3-pyrazolin-5-one, 245-284-9, Famprofazon, 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one, 3H-Pyrazol-3-one, 1,2-dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-, Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamino)methyl-, 1,2-Dihydro-1-methyl-4-(1-methylethyl)-5-((methyl(1-methyl-2-phenylethyl)amino)methyl)-2-phenyl-3H-pyrazol-3-one, Geodowin, Famprofazone [INN:BAN], Famprofazonum [INN-Latin], Famprofazona [INN-Spanish], 1,2-Dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-3H-pyrazol-3-one, 3H-Pyrazol-3-one, 1,2-dihydro-1-methyl-4-(1-methylethyl)-5-((methyl(1-methyl-2-phenylethyl)amino)methyl)-2-phenyl-, SR-01000838884, EINECS 245-284-9, UNII-HN0NCX453C, BRN 5768367, NCGC00016769-01, 3H-Pyrazol-3-one, 1,2-dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-; Famprofazone; 3-Pyrazolin-5-one, 4-isopropyl-2-methyl-3-[[methyl(alpha-methylphenethyl)amino]methyl]-1-phenyl- (8CI), 4-ISOPROPYL-2-METHYL-3-((METHYL(.ALPHA.-METHYLPHENETHYL)AMINO)METHYL)-1-PHENYL-3-PYRAZOLIN-5-ONE, 4-Isopropyl-2-methyl-3-([methyl(.alpha.-methylphenethyl)amino]methyl)-1-phenyl-3-pyrazolin-5-one, CAS-22881-35-2, Prestwick0_000703, Prestwick1_000703, Prestwick2_000703, Prestwick3_000703, Antipyrine, 4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))-, FAMPROFAZONE [INN], 3-(N-Methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine [French], BSPBio_000885, FAMPROFAZONE [MART.], 3H-Pyrazolin-5-one, 4-isopropyl-2-methyl-3-((methyl(alpha-methylphenethyl)amino)methyl)-1-phenyl-, MLS002153964, FAMPROFAZONE [WHO-DD], SCHEMBL893453, SPBio_002806, BPBio1_000975, CHEMBL1475693, CHEBI:93799, component of Gewodin (Salt/Mix), Famprofazone, analytical standard, GLXC-20247, HMS1570M07, HMS2097M07, HMS2235J18, HMS3369C14, HMS3714M07, Pharmakon1600-01505773, HY-B1054, MSK10945, Famprofazone 1.0 mg/ml in Methanol, Tox21_110600, BDBM50103614, MFCD00079304, NSC602800, NSC759244, AKOS015894771, Tox21_110600_1, CCG-213983, CS-4576, KS-1356, NSC 759244, NSC-602800, 3-(N-Methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine, NCGC00179385-01, NCGC00179385-03, 3H-Pyrazol-3-one,1,2-dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-, 4-isopropyl-1-methyl-5-((methyl(1-phenylpropan-2-yl)amino)methyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one, 4-Isopropyl-2-methyl-3- (methyl(alpha-methylphenethyl)amino)methyl -1-phenyl-3-pyrazolin-5-one, 4-Isopropyl-2-methyl-3-{(methyl(alpha-methylphenethyl)amino)methyl}-1-phenyl-3-pyrazolin-5-one, SMR001233303, SBI-0207052.P001, AB00513898, NS00003719, SW196346-3, H55246, AB00513898_06, AB00513898_07, Q5433492, SR-01000838884-2, SR-01000838884-3, BRD-A08255417-001-03-0, BRD-A08255417-001-06-3, BRD-A08255417-001-13-9, BRD-A08255417-001-14-7, Antipyrine, 4-isopropyl-3-(.alpha.-(methyl-(1-phenyl-2-propyl)amino))-, 3-(N,.alpha.-Dimethylphenethylaminomethyl)-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-one, 3-(N-Methyl-(.alpha.-methyl-.beta.-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantipyrine, 1-Methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one, 4-isopropyl-1-methyl-5-[[methyl-(1-methyl-2-phenyl-ethyl)amino]methyl]-2-phenyl-pyrazol-3-one
Theoretical properties:
molecular_formula: C24H31N3O
molecular_weight: 377.5 g/mol
exact_mass: 377.246712621 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 7
heavy_atom_count: 28
topological_polar_surface_area: 26.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-yl-3-pyrazolone is a member of pyrazoles and a ring assembly.
chembl: FAMPROFAZONE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Famprofazone (Gewodin, Gewolen) is a nonsteroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan. It has analgesic, anti-inflammatory, and antipyretic effects. Famprofazone has been known to produce methamphetamine as an active metabolite, with 15–20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing positives on drug tests for amphetamines.