Compound: piperidine-2-carboxylic acid
SMILES: O=C(O)C1NCCCC1
InChIKey: HXEACLLIILLPRG-UHFFFAOYSA-N
Synonyms: piperidine-2-carboxylic acid, Pipecolic acid, 535-75-1, Pipecolinic acid, 2-PIPERIDINECARBOXYLIC ACID, DL-Pipecolic acid, Dihydrobaikiane, Piperolinic acid, H254GW7PVV, NSC-17125, CHEBI:17964, DTXSID40862144, piperidin-1-ium-2-carboxylate, RefChem:863379, DTXCID70810951, 208-616-3, 223-737-1, DL-Pipecolinic acid, 4043-87-2, pipecolate, L-PipecolicAcid, Hexahydropicolinic acid, (R)-(+)-2-Piperidinecarboxylic acid, DL-Homoproline, Acide pipecolique, MFCD00064347, 2-Carboxypiperidine, 83680-83-5, (+/-)-Pipecolic acid, Hexahydro-2-picolinic acid, 2-Pipecolinic acid, Acide piperidine-carboxylique-2, .alpha.-Pipecolinic acid, (+/-)-2-Piperidinecarboxylic Acid, (+/-)-Pipecolinic acid, 2-Piperidinecarboxylic acidd, 2-Pyridine(carboxylic acid-13C1), Acide pipecolique [French], alpha-Pipecolinic acid, EINECS 208-616-3, EINECS 223-737-1, NSC 17125, UNII-H254GW7PVV, Pipecolinate, Pipecolinicacid, Piperolinate, Acide piperidine-carboxylique-2 [French], a-Pipecolinate, DL-Pipecolinate, DL-Pipecolate, alpha-Pipecolinate, Hexahydropicolinate, a-Pipecolinic acid, (+/-)-Piperidine-2-carboxylic acid, (+/-)-Pipecolate, (+/-)-Pipecolinate, 2-Piperidinecarboxylate, Hexahydro-2-picolinate, Pipecolic acid free base, (+/-) pipecolic acid, Pipecolinic acid, 98%, DL-2-Piperidinecarboxylate, 2-Piperidinylcarboxylic acid, 2-piperidine carboxylic acid, 2-piperidine-carboxylic acid, NCIOpen2_001582, PIPECOLIC ACID [MI], piperidine-6-carboxylic acid, SCHEMBL22016, (RS)-2-Piperidinecarboxylate, 2-Piperidinecarboxylic acid #, SCHEMBL133774, dl-2-piperidinecarboxylic acid, CHEMBL308408, orb1302539, orb3141132, SCHEMBL3020125, SCHEMBL3200924, SCHEMBL3843751, SCHEMBL5573673, SCHEMBL7178272, (+/-)-2-Piperidinecarboxylate, SCHEMBL11500684, SCHEMBL14632399, SCHEMBL27558661, SCHEMBL28168206, HXEACLLIILLPRG-UHFFFAOYSA-, rac piperidine-2-carboxylic acid, ()-Piperidine-2-carboxylic acid, MSK2073, (RS)-2-Piperidinecarboxylic acid, CS-B1313, HY-Y0669, NSC17125, NSC93089, PIPECOLIC ACID DL-FORM [MI], AC-691, s6322, STL183326, AKOS000120345, AKOS016050399, (.+/-.)-2-Piperidinecarboxylic acid, AB00554, AC-2835, EBC-151169, FP34562, PS-5851, 2-Piperidinecarboxylic acid, (.+/-.)-, SY002975, DB-038159, NS00074152, P0442, ST50680410, EN300-20680, F024932, Q7197255, F2191-0193, Z104479780, D(+)-Pipecolinic acid;  (R)-(+)-2-Piperidinecarboxylic acid, InChI=1/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)
Theoretical properties:
molecular_formula: C6H11NO2
molecular_weight: 129.16 g/mol
exact_mass: 129.078978594 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 1
heavy_atom_count: 9
topological_polar_surface_area: 49.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 264 °C
solubility: 314 mg/mL
Descriptions:
pubchem: Pipecolic acid is a piperidinemonocarboxylic acid in which the carboxy group is located at position C-2. It is a conjugate acid of a pipecolate.
chebi: A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
chembl: PIPECOLIC ACID is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: L-proline amide hydrolase (EC 3.5.1.101, S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase, LaaA, L-amino acid amidase) is an enzyme with systematic name (S)-piperidine-2-carboxamide amidohydrolase. This enzyme catalyses the following chemical reaction

(1) (S)-piperidine-2-carboxamide + H2O 
  
    
      
        ⇌
      
    
    {\displaystyle \rightleftharpoons }
  
  (S)-piperidine-2-carboxylic acid + NH3
(2) L-prolinamide + H2O 
  
    
      
        ⇌
      
    
    {\displaystyle \rightleftharpoons }
  
 L-proline + NH3