Compound: pindolol
SMILES: O(c1c2c([nH]cc2)ccc1)CC(O)CNC(C)C
InChIKey: JZQKKSLKJUAGIC-UHFFFAOYSA-N
Synonyms: pindolol, 13523-86-9, Visken, Prinodolol, Betapindol, Carvisken, Calvisken, Durapindol, Pinbetol, Decreten, Pectobloc, Pynastin, Blocklin L, LB-46, Glauco-visken, Blocklin-L, Pindololum, DL-Pindolol, LB 46, Apo-pindol, (rs)-pindolol, 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol, 4-(2-Hydroxy-3-isopropylaminopropoxy)-indole, 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol, 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol, 1-((1-Methylethyl)amino)-3-(4-indolyloxy)-2-propanol, DTXSID8023476, Dl-lb-46, BJ4HF6IU1D, NSC-757276, 1-(1H-Indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol, 2-Propanol, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-, 2-Propanol, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol, CHEBI:8214, DTXCID603476, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol, Prindolol, 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol, 2-Propanol, 1-(indol-4-yloxy)-3-(isopropylamino)-, (+-)-, LB46, pindololo, 1-(1H-indol-4-yloxy)-3-((propan-2-yl)amino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)propan-2-ol, RefChem:55861, C07AA03, (A+-)-LB-46, (2RS)-1-(1H-Indol-4-yloxy)-3-(1-methylethyl)aminopropan-2-ol, 236-867-9, Blockin L, 4-(3-(Isopropylamino)-2-hydroxypropoxy)indole, 2-Propanol, 1-(4-indolyloxy)-3-(isopropylamino)-, 1-((1H-indol-4-yl)oxy)-3-(isopropylamino)propan-2-ol, Glauco-Viskin, MFCD00010530, NCGC00015786-11, 2-Propanol, 1-(1H-indol-4-yloxy)-3-(1-methylethyl)amino-, (+-)-Pindolol, (+/-)-LB-46, Pindololum [INN-Latin], DL-4-[2-Hydroxy-3-(isopropylamino)propoxy]indole, Blocklin, Carvisken (TN), SMR000059120, Blocklin-L (TN), Visken (TN), CCRIS 9215, HSDB 6539, SR-01000000027, EINECS 236-867-9, EINECS 244-623-8, UNII-BJ4HF6IU1D, BRN 1536506, DL-4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)INDOLE, 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol, DL-LB 46, Prindolol;, Pindolol CRS, Prestwick_397, CAS-13523-86-9, Pindolol (Standard), Pindolol [USAN:USP:INN:BAN:JAN], Spectrum_001109, (-)-Pindolol; (S)-(-)-Pindolol; S-Pindolol, (1)-1-(1H-Indol-4-yloxy)-3-(isopropylamino)propan-2-ol, PINDOLOL [HSDB], PINDOLOL [USAN], PINDOLOL [INN], PINDOLOL [JAN], PINDOLOL [MI], PINDOLOL [VANDF], (.+/-.)-Pindolol, Prestwick0_000090, Prestwick1_000090, Prestwick2_000090, Prestwick3_000090, Spectrum2_001285, Spectrum3_000547, Spectrum4_000479, Spectrum5_001266, PINDOLOL [MART.], CHEMBL500, GTPL91, PINDOLOL [USP-RS], PINDOLOL [WHO-DD], PINDOLOL,(-), P 0778, SCHEMBL5219, Lopac0_000955, Oprea1_770884, (+/-)-PINDOLOL, BSPBio_000020, BSPBio_002193, KBioGR_000958, KBioSS_001589, 5-21-03-00017 (Beilstein Handbook Reference), MLS000069496, MLS002548891, DivK1c_000837, SPECTRUM1500488, Pindolol (JP18/USP/INN), SPBio_001289, SPBio_001959, PINDOLOL [ORANGE BOOK], 2-Propanol, 1-(indol-4-yloxy)-3-(isopropylamino)-, BPBio1_000022, orb2703260, orb3029220, PINDOLOL [EP MONOGRAPH], PINDOLOL [USP MONOGRAPH], SCHEMBL29908300, HMS502J19, HY-B0982R, KBio1_000837, KBio2_001589, KBio2_004157, KBio2_006725, KBio3_001693, NINDS_000837, HMS1568A22, HMS1920H16, HMS2089I21, HMS2091P20, HMS2095A22, HMS3259I07, HMS3262P12, HMS3267K17, HMS3369E14, HMS3414J03, HMS3678H21, HMS3712A22, HMS3742C07, HMS3885N04, HMS5083C21, Pharmakon1600-01500488, VISKAZIDE COMPONENT PINDOLOL, HY-B0982, MSK10061, Pindolol, >=98% (TLC), powder, Tox21_110221, Tox21_500955, BDBM50019443, CCG-39223, EBC-26316, NSC757276, PDSP1_000771, PDSP1_000772, PDSP2_000759, PDSP2_000760, AKOS015969756, Tox21_110221_1, CS-4473, DB00960, LP00955, NC00467, NSC 757276, SB17015, SDCCGSBI-0050929.P005, IDI1_000837, NCGC00015786-06, NCGC00015786-07, NCGC00015786-08, NCGC00015786-09, NCGC00015786-10, NCGC00015786-13, NCGC00015786-14, NCGC00015786-16, NCGC00015786-20, NCGC00015786-22, NCGC00024925-03, NCGC00024925-04, NCGC00024925-05, NCGC00024925-06, NCGC00024925-07, NCGC00261640-01, BS-42390, DA-66729, SBI-0050929.P004, 4-(3-Isopropylamino-2-hydroxypropoxy)indole, AB00052072, EU-0100955, NS00007947, ST50319990, SW196641-3, T0735, C07445, C90604, D00513, AB00052072-11, AB00052072_12, AB00052072_13, 1-(4-Indolyloxy)-3-(isopropylamino)-2-propanol, EN300-18518413, L000006, Q418101, 3-indol-4-yloxy-1-[(methylethyl)amino]propan-2-ol, 4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDOLE, SR-01000000027-2, SR-01000000027-4, SR-01000000027-5, SR-01000000027-7, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol, BRD-A97701745-001-05-3, BRD-A97701745-001-09-5, BRD-A97701745-001-14-5, BRD-A97701745-001-15-2, BRD-A97701745-001-16-0, 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol #, Pindolol, European Pharmacopoeia (EP) Reference Standard, (+/-)-4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)INDOLE, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol), 1-[(1H-Indol-4-yl)oxy]-3-[(propan-2-yl)amino]propan-2-ol, Pindolol, United States Pharmacopeia (USP) Reference Standard, 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol), N-(2-HYDROXY-3-(1H-INDOL-4-YLOXY)PROPYL)-N-ISOPROPYLAMINE
Theoretical properties:
molecular_formula: C14H20N2O2
molecular_weight: 248.32 g/mol
exact_mass: 248.152477885 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 3
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 6
heavy_atom_count: 18
topological_polar_surface_area: 57.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Crystals from ethanol
color: Crystals from ethanol
odor: Faint odor
solubility: Practically Insoluble
Descriptions:
pubchem: Pindolol is a member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1H-indol-4-ol. It has a role as a beta-adrenergic antagonist, a vasodilator agent, an antihypertensive agent, an antiglaucoma drug and a serotonergic antagonist. It is a member of indoles and a secondary amine.
chebi: A member of the class of indols which is the 2-hydroxy-3-(isopropylamino)propyl ether derivative of 1<em>H</em>-indol-4-ol.
chembl: PINDOLOL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Pindolol, sold under the brand name Visken among others, is a non-selective beta blocker which is used in the treatment of hypertension. It is also an antagonist of the serotonin 5-HT1A receptor, preferentially blocking inhibitory 5-HT1A autoreceptors, and has been researched as an add-on therapy to various antidepressants, such as clomipramine and the selective serotonin reuptake inhibitors (SSRIs), in the treatment of depression and obsessive–compulsive disorder (OCD).