Compound: 2487-48-1
SMILES: O=C1[C@@]2([C@H]([C@@H]3[C@@H](O)C=C4C[C@@H](O)CC[C@@]4([C@H]3CC2)C)CC1)C
InChIKey: OLPSAOWBSPXZEA-GCNMQWDSSA-N
Synonyms: 2487-48-1, 7beta-hydroxydehydroepiandrosterone, 7b-Hydroxydehydroepiandrosterone, 7b-Hydroxy-DHEA, 7beta-Hydroxy-dhea, 923RBW7OJQ, 7-b-OH-DHEA, UNII-923RBW7OJQ, androst-5-en-17-one-3beta,7beta-diol, 7.BETA.-HYDROXY-DHEA, Androst-5-en-17-one, 3,7-dihydroxy-, (3beta,7beta)-, 7b-Hydroxy dehydroepiandrosterone, DTXSID50431284, 3b,7b-dihydroxy-ost-5-en-17-one, Androst-5-ene-3b,7b-diol-17-one, 3b,7b-Dihydroxy-5-androsten-17-one, 3b,7b-Dihydroxy-5-androstene-17-one, 3b,7b-dihydroxy-Androst-5-en-17-one, Androst-5-ene-17-one-3beta,7beta-diol, Androst-5-ene-3beta,7beta-diol-17-one, 3alpha,7beta-Hydroxyandrost-5-en-17-one, 3beta,7-Dihydroxy-5-etioallocholen-17-one, 7.BETA.-HYDROXYDEHYDROEPIANDROSTERONE, Androst-5-en-17-one, 3beta,7beta-dihydroxy-, (3b,7b)-3,7-dihydroxy-Androst-5-en-17-one, (3beta,7beta)-3,7-Dihydroxyandrost-5-en-17-one, ANDROST-5-EN-17-ONE-3.BETA.,7.BETA.-DIOL, 3.ALPHA.,7.BETA.-HYDROXYANDROST-5-EN-17-ONE, 3.BETA.,7-DIHYDROXY-5-ETIOALLOCHOLEN-17-ONE, ANDROST-5-ENE-17-ONE-3.BETA.,7.BETA.-DIOL, ANDROST-5-ENE-3.BETA.,7.BETA.-DIOL-17-ONE, ANDROST-5-EN-17-ONE, 3.BETA.,7.BETA.-DIHYDROXY-, (3.BETA.,7.BETA.)-3,7-DIHYDROXYANDROST-5-EN-17-ONE, ANDROST-5-EN-17-ONE, 3,7-DIHYDROXY-, (3.BETA.,7.BETA.)-, 3beta,7beta-dihydroxy-5-androsten-17-one, 7beta-OH-DHEA, CHEBI:183368, 3beta,7beta-dihydroxy-5-androstene-17-one, RefChem:106648, DTXCID00382116, (3aS,3bR,4R,7S,9aR,9bS,11aS)-4,7-dihydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta(a)phenanthren-1-one, (3aS,3bR,4R,7S,9aR,9bS,11aS)-4,7-dihydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-one, 7 alpha-hydroxydehydroepiandrosterone, 7-beta-OH-DHEA, (3S,7R,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one, 5-Androsten-3-beta, 7-beta-diol-17-one, 7b-Hydroxy Dehydro Epiandrosterone, 3beta,7beta-dihydroxyandrost-5-en-17-one, 7b-Hydroxy Dehydro Epiandrosterone (1.0 mg/mL in Acetonitrile), (3aS,3bR,4R,7S,9aR,9bS,11aS)-4,7-dihydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one, 7|?-Hydroxy dhea, 7-.BETA.-OH-DHEA, SCHEMBL602258, Androst-5-en-17-one, 3,7-dihydroxy-, (3b,7b)-, CHEMBL1082098, OLPSAOWBSPXZEA-GCNMQWDSSA-N, CAA48748, LMST02020106, MFCD00198721, 5-Androsten-3?, 7?-diol-17-one, AKOS027327553, MSK000371-100A, AS-31472, "7b-Hydroxy DHEA * (for WADA labs, only)", Q27271468, 7beta-Hydroxy DHEA Solution in Acetonitrile, 100ug/mL, (3S,7R,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one
Theoretical properties:
molecular_formula: C19H28O3
molecular_weight: 304.4 g/mol
exact_mass: 304.20384475 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 0
heavy_atom_count: 22
topological_polar_surface_area: 57.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 213 - 215 °C
Descriptions:
chebi: An androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7β-position. It is a metabolite of dehydroepiandrosterone.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: 7β-Hydroxydehydroepiandrosterone (7β-hydroxy-DHEA; 7β-OH-DHEA), also known as 3β,7β-dihydroxyandrost-5-ene-17-one, is an endogenous, naturally occurring steroid and a metabolite of dehydroepiandrosterone (DHEA). The major metabolic pathway of DHEA outside the liver is via 7-hydroxylation into 7α-OH-DHEA and 7β-OH-DHEA. 7β-OH-DHEA has weak antiestrogenic activity, selectively antagonizing the estrogen receptor ERβ.
7β-OH-DHEA is on the World Anti-Doping Agency list of prohibited substances in sporting.