Compound: trihexyphenidyl
SMILES: OC(c1ccccc1)(C2CCCCC2)CCN3CCCCC3
InChIKey: HWHLPVGTWGOCJO-UHFFFAOYSA-N
Synonyms: trihexyphenidyl, Benzhexol, 144-11-6, Triphenidyl, Trihexyphenidyle, Benzhexolum, Trihexifenidilo, Trihexyphenidylum, Apo-Trihex, 1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol, 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl-, 6RC5V8B7PO, NSC-12268, DTXSID4023705, 5-20-02-00231 (Beilstein Handbook Reference), Triesifenidile, Pacitane, Pargitan, ApoTrihex, Atan, Apo Trihex, (+-)-Trihexyphenidyl, RefChem:56168, DTXCID703705, N04AA01, cyclodolum (for the hydrochloride), 205-614-4, Trihexylphenedyl, Parkinane retard, Sedrena (free base), Trihexifenidilo [INN-Spanish], Trihexyphenidyle [INN-French], Trihexyphenidylum [INN-Latin], Benzhexol free base, 1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol, Trihexyphenidyl (INN), (+/-)-Trihexyphenidyl, 1-Piperidinepropanol, .alpha.-cyclohexyl-.alpha.-phenyl-, 1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol, Trihexylphenidyl, Trihexylphenizyl, Trihexylphenidyle, TRIHEXYPHENIDYL [INN], Trihexyphenidyl [INN:BAN], Apo-trihex (TN), (+/-)-Triphenidyl; Benzhexol; NSC 12268, HSDB 3196, EINECS 205-614-4, NSC 12268, UNII-6RC5V8B7PO, BRN 0088959, 144-11-6 (free base), Spectrum_000632, Prestwick0_000701, Prestwick1_000701, Prestwick2_000701, Prestwick3_000701, Spectrum2_000829, Spectrum3_001375, Spectrum4_000369, Spectrum5_001465, 1-Piperidinepropanol, ?-cyclohexyl-?-phenyl-, CHEMBL1490, Lopac0_001125, Oprea1_853391, SCHEMBL34645, BSPBio_000881, BSPBio_002930, KBioGR_000837, KBioSS_001112, DivK1c_000372, TRIHEXYPHENIDYL [HSDB], SPBio_000757, SPBio_002802, TRIHEXYPHENIDYL [VANDF], 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl-,, BPBio1_000971, CHEBI:9720, GTPL7315, TRIHEXYPHENIDYL [WHO-DD], BDBM81462, KBio1_000372, KBio2_001112, KBio2_003680, KBio2_006248, KBio3_002150, NINDS_000372, NSC_5572, NSC12268, EBC-26537, MFCD00599600, STL300356, AKOS015914081, CCG-205200, DB00376, SDCCGSBI-0051093.P004, IDI1_000372, MRF-0000523, NCGC00016003-03, NCGC00016003-04, NCGC00016003-06, NCGC00016003-07, NCGC00016003-15, NCGC00089797-02, ()-Triphenidyl; Benzhexol; NSC 12268, DA-58731, LS-14821, SBI-0051093.P003, CAS_58947-95-8, AB00053559, NS00006523, ( inverted exclamation mark_)-Trihexyphenidyl, C07171, D08638, EN300-708793, G78220, 1-Piperidinepropanol, |A-cyclohexyl-|A-phenyl-, AB00053559_13, alpha-Cyclohexyl-alpha-phenyl-1-piperidinepropanol, L000821, Q2991856, BRD-A48180038-003-05-2, BRD-A48180038-003-15-1, BRD-A48180038-003-24-3, .alpha.-Cyclohexyl-.alpha.-phenyl-1-piperidinepropanol, 1-Cyclohexyl-1-phenyl-3-(1-piperidinyl)-1-propanol #
Theoretical properties:
molecular_formula: C20H31NO
molecular_weight: 301.5 g/mol
exact_mass: 301.240564612 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 5
heavy_atom_count: 22
topological_polar_surface_area: 23.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: Crystals; decomp at 258.5 °C; pH of 1% aq soln 5.5-6.0; solubility (g/100 mL): water at 25 °C 1.0, alcohol 6, chloroform 5; more soluble in methanol; very slightly soluble in ether, benzene /Hydrochloride/
Descriptions:
pubchem: Trihexyphenidyl is an amine.
chembl: TRIHEXYPHENIDYL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Trihexyphenidyl (THP,  benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used  in management of Parkinson's disease. It was approved by the FDA for the treatment of Parkinson's in the US in 1949.
Trihexyphenidyl is a therapeutic alternative on the World Health Organization's List of Essential Medicines.