Compound: 88847-89-6
SMILES: O=c1nc([nH]c2c1[nH]c(=O)n2[C@@H]3O[C@H](CO)[C@H](C3)O)N
InChIKey: HCAJQHYUCKICQH-VPENINKCSA-N
Synonyms: 88847-89-6, 8-Hydroxy-2'-deoxyguanosine, 8-Oxo-2'-deoxyguanosine, 8-Oxo-dG, 8-Hydroxydeoxyguanosine, 8-Oxo-7,8-dihydro-2'-deoxyguanosine, 2'-deoxy-8-oxoguanosine, 8-Oxo-7-hydrodeoxyguanosine, 8-OHdG, Guanosine, 2'-deoxy-7,8-dihydro-8-oxo-, 8-Oxo-2'-deoxyguanine, 8-oxodG, 8-Oxo-deoxyguanosine, 8-hydroxy-2-deoxyguanosine, 2'-deoxy-8-hydroxyguanosine, 2'-deoxy-7,8-dihydro-8-oxoguanosine, 7,8-Dihydro-2'-deoxy-8-oxoguanosine, 4RGB38T3IB, CHEBI:40304, DTXSID60904338, 8-OH-dG, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione, 8-oxodGuo, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,7-dihydropurine-6,8-dione, 8-oxo-dGuo, 8 Oxo Deoxyguanosine, 8OHdG, 8 Hydroxydeoxyguanosine, 2' Deoxy 8 Oxoguanosine, 8 Oxo 2' Deoxyguanosine, 7-hydro-8-oxodeoxyguanosine, 7 Hydro 8 Oxodeoxyguanosine, 8 Oxo 7 Hydrodeoxyguanosine, 2' Deoxy 8 Hydroxyguanosine, 8 Hydroxy 2' Deoxyguanosine, 8 Oxo 7,8 Dihydrodeoxyguanosine, 2-amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,7-dihydropurine-6,8-dione, 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-3,7-dihydropurine-6,8-dione, 2' Deoxy 7,8 Dihydro 8 Oxoguanosine, 2' Deoxy 8 Oxo 7,8 Dihydroguanosine, 7,8 Dihydro 8 Oxo 2' Deoxyguanosine, 8 Oxo 7,8 Dihydro 2' Deoxyguanosine, RefChem:914563, DTXCID001333494, 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purine-6,8(7H,9H)-dione, 8-hydroxy-deoxyguanosine, MFCD00210311, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,7,8,9-tetrahydro-3H-purine-6,8-dione, 2-amino-8-hydroxy-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one, 8HG, 8-oxo-7,8-dihydrodeoxyguanosine, 7,8-dihydro-8-oxo-2'-deoxyguanosine, CCRIS 8239, 7,8-Dihydro-8-oxodeoxyguanosine, oh8dG, CID 5287560, 8-Hydroxydesoxyguanosin, 2a5b, 8-hydroxydeoxy-guanosine, Guanosine, 7,8-dihydro-2'-deoxy-8-oxo-, 8-oxo-2'-dG, Epitope ID:151526, UNII-4RGB38T3IB, 8-hydroxy-2'deoxyguanosine, Discontinued See O850250, SCHEMBL114652, SCHEMBL500620, SCHEMBL529452, 2'-Deoxy-8-oxo-D-guanosine, 8-Hydroxy-2''-deoxyguanosine, orb1299017, orb3141503, CHEMBL1230628, HMS3649O10, MSK11447, MFCD28101734, AKOS024262435, CS-W012256, DB02502, EBC-616048, HY-W011540, ND06344, NCGC00475978-01, 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3,7-dihydropurine-6,8-dione, AC-32342, AS-74648, SY078071, NS00071333, A12921, 2 inverted exclamation mark -Deoxy-8-oxoguanosine, F460639, Q270154, SR-01000946628, SR-01000946628-1, 8-Hydroxy-2 inverted exclamation marka-deoxyguanosine, 2-Amino-9-(2-deoxyribofuranosyl)-3,7-dihydropurine-6,8-dione, 2-amino-8-hydroxy-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one, 7,8-Dihydro-8-oxo-2'-deoxyguanosine, 2'-Deoxy-7,8-dihydro-8-oxoguanosine, 8-Oxo-7,8-dihydrodeoxyguanosine, 8-Oxo-7,8-dihydro-2'-deoxyguanosine, 7,8-Dihydro-8-oxodeoxyguanosine, 8-Hydroxydeoxyguanosine,Guanosine, 2'-deoxy-7,8-dihydro-8-oxo-, 8-Oxodeoxyguanosine, 8-Hydroxy-2'-deoxyguanosine, 8-Oxo-2'-deoxyguanosine, 8-Oxo-dG
Theoretical properties:
molecular_formula: C10H13N5O5
molecular_weight: 283.24 g/mol
exact_mass: 283.09166853 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 5
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 2
heavy_atom_count: 20
topological_polar_surface_area: 150 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 8-hydroxy-2'-deoxyguanosine is guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage. It has a role as a biomarker.
chebi: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: 8-Oxo-2'-deoxyguanosine (8-oxo-dG) is an oxidized derivative of deoxyguanosine.  8-Oxo-dG is one of the major products of DNA oxidation.  Concentrations of 8-oxo-dG within a cell are a measurement of oxidative stress.