Compound: ETHACRIDINE LACTATE
SMILES: O=C(O)C(O)C.O(c1cc2c(N)c3c(cc(N)cc3)nc2cc1)CC
InChIKey: IYLLULUTZPKQBW-UHFFFAOYSA-N
Synonyms: ETHACRIDINE LACTATE, 1837-57-6, acrinol, Rivanol, 6,9-Diamino-2-ethoxyacridine lactate, Metifex, Rimaon, Vucine, Ethodin, Antidiar 200, ETHACRIDINE LACTATE ANHYDROUS, NSC-36333, 7T7T2I9823, DTXSID10872472, Neo Chinosol, Lactate, Ethacridine, RefChem:921193, DTXCID00820129, 217-408-1, 642-272-9, Acrolactin, V5IL571C1T, Acrolactine, 7-ethoxyacridine-3,9-diamine 2-hydroxypropanoate, Rivinol, Flavitrol, Hectalin, Amoebin, Akron, Ethacridine (lactate), 2-Ethoxy-6,9-diaminoacridine lactate, NSC 36333, MFCD00013149, 2,5-Diamino-7-ethoxyacridine lactate, 2-Ethoxy-6,9-diaminoacridinium lactate, 3,9-Diamino-7-ethoxyacridinium lactate, TCMDC-123983, Acrinolum, 7-ethoxyacridine-3,9-diamine;2-hydroxypropanoic acid, CCRIS 5165, NCGC00096056-02, EINECS 217-408-1, Acridine, 6,9-diamino-2-ethoxy-, lactate, Acrinol;, 2-Aethoxy-6,9-diaminoacridinlactat [German], UNII-7T7T2I9823, Acridine, 6,9-diamino-2-ethoxy-, monolactate, 2-Aethoxy-6,9-diaminoacridinlactat, Propanoic acid, 2-hydroxy-, compd. with 7-ethoxy-3,9-acridinediamine (1:1); 6,9-Diamino-2-ethoxyacridine lactate; Lactic acid compd. with 6,9-diamino-2-ethoxyacridine (1:1); 7-Ethoxy-3,9-acridinediamine 2-hydroxypropanoate (1:1); 6,9-Diamino-2-ethoxyacrid, Antidian 200, 6,9-Acridinediamine, 2-ethoxy-, 2-hydroxypropanoate (1:1), SCHEMBL138154, SPECTRUM1505168, CHEMBL582355, orb1301378, SCHEMBL30006678, SCHEMBL30775016, SCHEMBL31197660, CHEBI:31172, IYLLULUTZPKQBW-UHFFFAOYSA-N, HMS3264O11, HMS5086L16, Pharmakon1600-01505168, HY-B2174, NSC36333, ETHACRIDINE LACTATE [WHO-DD], NSC758932, s4945, AKOS015896231, Acridine,9-diamino-2-ethoxy-, lactate, CCG-213965, CS-7625, KS-5135, NSC-758932, WLN: T C666 BNJ EZ IZ LO2, NCGC00096056-01, SY110727, Acridine,9-diamino-2-ethoxy-, monolactate, 7-ethoxy-3,9-acridinediamine, lactate salt, DB-044505, (+/-)-ETHACRIDINE LACTATE ANHYDROUS, 6, 2-ethoxy-, 2-hydroxypropanoate (1:1), A0136, NS00093573, D81748, ETHACRIDINE LACTATE ANHYDROUS, (+/-)-, Lactic acid,9-diamino-2-ethoxyacridine (1:1), Q426220, SR-01000872749, SR-01000872749-1, Acridine,9-diamino-2-ethoxy-, cpd with lactic acid (1:1), 2-Hydroxypropanoic acid--7-ethoxyacridine-3,9-diamine (1/1)
Theoretical properties:
molecular_formula: C18H21N3O4
molecular_weight: 343.4 g/mol
exact_mass: 343.15320616 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 7
rotatable_bond_count: 3
heavy_atom_count: 25
topological_polar_surface_area: 132 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 2
Physical properties:
Descriptions:
pubchem: Acrinol is an organic molecular entity.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Ethacridine lactate (ethacridine monolactate monohydrate, acrinol, trade name Rivanol) is an aromatic organic compound based on acridine. Its formal name is 2-ethoxy-6,9-diaminoacridine monolactate monohydrate.  It forms orange-yellow crystals with a melting point of 226 °C and it has a stinging smell.
Its primary use is as an antiseptic in solutions of 0.1%. It is effective against mostly Gram-positive bacteria, such as Streptococci and Staphylococci, but ineffective against Gram-negative bacteria such as Pseudomonas aeruginosa.
Ethacridine is also used as an agent for second trimester abortion.  Up to 150 ml of a 0.1% solution is instilled extra-amniotically using a foley catheter. After 20 to 40 hours, 'mini labor' ensues.  In China, an intra-amniotic method has also been used.  Ethacridine as an abortifacient is found to be safer and better tolerated than 20% hypertonic saline.