Compound: d-Tranylcypromine
SMILES: N[C@H]1[C@H](c2ccccc2)C1
InChIKey: AELCINSCMGFISI-DTWKUNHWSA-N
Synonyms: d-Tranylcypromine, (1R,2S)-tranylcypromine, (+)-(R)-Tranylcypromine, CHEBI:131510, DTXSID201015773, RefChem:1049437, DTXCID803694, (1R,2S)-2-phenylcyclopropan-1-amine, 3721-26-4, (1R,2S)-2-phenylcyclopropanamine, Parnate, 95-62-5, trans-2-Phenylcyclopropylamine, trans-2-phenyl-cyclopropylamine, rel-Tranylcypromine, Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-, MFCD00865363, (-)-Tranylcypromine, l-Tranylcypromine, rac-(1R,2S)-2-phenylcyclopropan-1-amine, NSC 80664, CHEMBL1179, (1R,2S)-2-phenyl-cyclopropylamine, MFCD00001302, trans-DL-2-Phenylcyclopropylamine, trans-(-)-2-Phenylcyclopropanamine, Cyclopropanamine, 2-phenyl-, trans-(.+/-.)-, Cyclopropylamine, 2-phenyl-, trans-(.+/-.)-, 2-Phenyl-1-aminocyclopropane, trans-, Parnate (Salt/Mix), (rel)-Tranylcypromine, SKF-trans-385, (1r,2s)-rel-2-phenylcyclopropanamine, 2-Phenyl-cyclopropylamine, Cyclopropylamine, 2-phenyl-, (1S-trans)-, (.+/-.)-Tranylcypromine, SKF Trans-385, TRANYLCYPROMINE [INN], Tranylcypromine [INN:BAN], trans-2-phenylcyclopropan-1-amine, Tranylcyprominum [INN-Latin], trans amine, trans-amine, UNII-3E3V44J4Z9, Tranilcipromina [INN-Spanish], CCRIS 3344, (+/-)-trans-2-phenylcyclopropylamine, HSDB 3404, (.+/-.)-trans-2-Phenylcyclopropamine, (.+/-.)-trans-2-Phenylcyclopropylamine, GJZ, Cyclopropanamine, 2-phenyl-, (1S,2R)-, EINECS 205-841-9, BRN 2802413, BRN 3195803, (1R,2S)-rel-2-phenylcyclopropan-1-amine, Cyclopropylamine, 2-phenyl-, trans-(-)-, Cyclopropanamine, 2-phenyl-, (1R-trans)-, Prestwick0_000173, Prestwick1_000173, Prestwick2_000173, Lopac-P-8511, CBChromo1_000132, TRANYLCYPROMINE [MI], SCHEMBL34339, TRANYLCYPROMINE [HSDB], SPBio_001986, TRANYLCYPROMINE [VANDF], SCHEMBL5664907, trans-2-phenyl cyclopropylamine, (1R,2S)-trans-tranylcypromine, SCHEMBL16268040, SCHEMBL17092910, TRANYLCYPROMINE [WHO-DD], (Trans)-2-phenylcyclopropanamine, [trans-2-phenylcyclopropyl]amine, CHEBI:94631, cid_2723716, [(trans)-2-phenylcyclopropyl]amine, BDBM50240772, EBC-44100, NSC789036, PDSP2_001079, PDSP2_001080, (1R-trans)-2-phenyl-cyclopropanamine, AKOS006282586, (1R,2S)-2-phenyl-1-cyclopropanamine, cyclopropane, trans-1-amino-2-phenyl-, NSC-789036, (1R,2S)-(-)-2-phenylcyclopropylamine, NCGC00015848-01, NCGC00015848-07, NCGC00015848-09, (tranylcypromine)2-Phenyl-cyclopropylamine, AC-15970, BS-50045, DA-77397, SY268491, rel-(1R,2S)-2-phenylcyclopropan-1-amine, Ticagrelor Impurity 240 (Tranylcypromine), CS-0099373, trans-(1R,2S)-2-Phenylcyclopropan-1-amine, EN300-197006, EN300-253001, F605604, BRD-K47029922-003-03-4, BRD-K47029922-003-10-9, BRD-K47029922-003-11-7, dl-Tranylcypromine; Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-
Theoretical properties:
molecular_formula: C9H11N
molecular_weight: 133.19 g/mol
exact_mass: 133.089149355 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 1
heavy_atom_count: 10
topological_polar_surface_area: 26 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: (1R,2S)-tranylcypromine is a 2-phenylcyclopropan-1-amine that is the (1R,2S)-enantiomer of tranylcypromine. It is a conjugate base of a (1R,2S)-tranylcypromine(1+). It is an enantiomer of a (1S,2R)-tranylcypromine.
chebi: A 2-phenylcyclopropan-1-amine that is the (1<i>R</i>,2<i>S</i>)-enantiomer of tranylcypromine.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Tranylcypromine, sold under the brand name Parnate among others, is a monoamine oxidase inhibitor (MAOI). More specifically, tranylcypromine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). It is used as an antidepressant and anxiolytic agent in the clinical treatment of mood and anxiety disorders, respectively. It is also effective in the treatment of  ADHD.
Tranylcypromine is also known as trans-2-phenylcyclopropyl-1-amine and is formed pro forma from the cyclization of amphetamine's isopropylamine side chain. As a result, it is classified structurally as a substituted phenethylamine and amphetamine, or more specifically as a phenylcyclopropylamine.