Compound: Di-tert-butyl dicarbonate
SMILES: O=C(OC(=O)OC(C)(C)C)OC(C)(C)C
InChIKey: DYHSDKLCOJIUFX-UHFFFAOYSA-N
Synonyms: Di-tert-butyl dicarbonate, 24424-99-5, di-tert-Butyl pyrocarbonate, Bis(tert-butoxycarbonyl)oxide, BOC-anhydride, Boc2O, Di-tert-butyldicarbonate, Dicarbonic acid, bis(1,1-dimethylethyl) ester, Di(tert-butyl) carbonate, Z10Q236C3G, DTXSID4051904, Boc2O cpd, Boc(2)O cpd, RefChem:132516, DTXCID9030466, 246-240-1, BOC anhydride, di-t-Butyl dicarbonate, tert-Butoxycarbonyl anhydride, Diboc, Di-t-butyl pyrocarbonate, tert-Butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester, di-t-butyldicarbonate, di-t-butyl-dicarbonate, ditert-butyldicarbonate, tert-butyl (2-methylpropan-2-yl)oxycarbonyl carbonate, di-tert-butyl-dicarbonate, MFCD00008805, bis(tert-butyl) dicarbonate, tert-butoxycarbonyl tert-butyl carbonate, Di-tert-butyl dicarbonate 2.0M in THF, Di-tert-butyl dicarbote, tert-butyl (tert-butoxycarbonyloxy)formate, di-tert butyl dicarbonate, (boc)2o, CCRIS 2598, ditertbutyl dicarbonate, EINECS 246-240-1, UNII-Z10Q236C3G, tBoc2O, diterbutyldicarbonate, ditertbutyldicarbonate, di t-butyldicarbonate, di-t butyldicarbonate, diterbutyl dicarbonate, diterbutyl-dicarbonate, t-Boc2O, Di-t-butyidicarbonate, di-tertbutyldicarbonate, ditert butyldicarbonate, ditertbutyl-dicarbonate, di t butyl dicarbonate, di t-butyl dicarbonate, di(t-butyl)dicarbonate, di-t -butyldicarbonate, di-t butyl dicarbonate, di-t butyl-dicarbonate, di-t-butylpyrocarbonate, di-ter-butyldicarbonate, di-terbutyl dicarbonate, di-tert-butydicarbonate, di-tert-butyldicarbonat, (tBoc)2O, Di-tert-buyldicarbonate, di tert butyldicarbonate, di tert-butyldicarbonate, di tert.butyldicarbonate, di-tert butyldicarbonate, di-tert-butyidicarbonate, di-tert.butyldicarbonate, di-tertbutyl dicarbonate, di-tertbutyl-dicarbonate, ditert-butyl dicarbonate, ditert-butyl-dicarbonate, ditert.butyl dicarbonate, Di-tert-butlydicarbonate, di-tertbutylpyrocarbonate, Ditert butyl dicarbonate, di(t-butyl) dicarbonate, di-(t-butyl)dicarbonate, di-ter-butyl dicarbonate, di-ter-butyl-dicarbonate, di-tert-butyl dicabonate, di-tert-butyl dicarbonat, di-tert-butyl-dicarbonat, di-tert.-butyldicarbonat, di-tert.butyl-dicarbonat, Di-tert-buty dicarbonate, bis(t-butyl)pyrocarbonate, di tert butyl dicarbonate, di tert.-butyldicarbonate, di(t-butoxycarbonyl)ether, di(tert-butyl)dicarbonate, di-tert-butly-dicarbonate, di-tert.-butyldicarbonate, di-tert.butyl dicarbonate, di-tert.butyl-dicarbonate, O(Boc)2, (tBuO2C)2O, Di tert-butyl dicarbonate, Di-tert -butyldicarbonate, Di-tert-butyldicarbon-ate, di-tert-butylpyrocarbonate, di-tert.butylpyrocarbonate, di-tertbutyl-pyrocarbonate, di-(t-butyl) dicarbonate, di-tertiarybutyldicarbonate, ditertiary butyldicarbonate, ditertiary-butyldicarbonate, ditertiarybutyl dicarbonate, bis(t-butoxycarbonyl)oxide, bis(tert-butyl)dicarbonate, Di-tert.-butyl-dicarbonat, Di-tert-butyloxy diformate, (di-tert-butyl)dicarbonate, di (tert-butyl)dicarbonate, di(tert-butyl) dicarbonate, di(tert-butyl)-dicarbonate, di(tert.butyl) dicarbonate, di-(tert-butyl)dicarbonate, di-tert -butyl dicarbonate, di-tert-butyl di carbonate, di-tert-butyl- dicarbonate, di-tert. butyl dicarbonate, di-tert. butyl-dicarbonate, di-tert.-butyl dicarbonate, di-tert.-butyl-dicarbonate, di(tert-butyl)pyrocarbonate, di-tert-butyl-pyrocarbonate, di-tert.-butylpyrocarbonate, di-tert.butyl pyrocarbonate, ditert.-butyl pyrocarbonate, di-tertiary-butyldicarbonate, di-tertiarybutyl dicarbonate, ditertiary butyl dicarbonate, EC 246-240-1, t-Butoxycarboxylic anhydride, (t-BOC)2O, bis(t-butoxycarbonyl) oxide, SCHEMBL5452, di(-tert.butyl) dicarbonate, di-(tert-butyl) dicarbonate, di-tert. butyl pyrocarbonate, di-tert.-butyl pyrocarbonate, di tertiary butyl dicarbonate, di-tertiary butyl dicarbonate, di-tertiary butyl-dicarbonate, di-tertiary-butyl dicarbonate, di-tertiary-butyl-dicarbonate, Di(tertiarybutyl) dicarbonate, Di-tert-butyl dicarbonate 2.0M in Dichloromethane, di-tert. -butyl pyrocarbonate, tert-butoxycarboxylic anhydride, orb1905825, CHEBI:48500, di(1,1-dimethylethyl)dicarbonate, bis(1,1-dimethylethyl)dicarbonate, dicarbonic acid di(t-butyl) ester, di(1,1-dimethylethyl) dicarbonate, Di-tert-butyl dicarbonate solution, pyrocarbonic acid di-t-butyl ester, Bis(1,1-dimethylethyl)dicarbonoate, bis(1,1'-dimethylethyl)dicarbonate, bis(1,1-dimethylethyl) dicarbonate, Bis(1,1-dimethylethyl)-dicarbonate, pyrocarbonic acid-di-tert-butylester, STR01939, tert-butoxycarboxylic acid anhydride, bis (1,1-dimethylethyl) dicarbonate, Bis(1,1-dimethylethyl) dicarbonoate, pyrocarbonic acid di-tert.butyl ester, pyrocarbonic acid-di-tert-butyl ester, SBB054122, 1,1-dimethylethoxycarboxylic anhydride, AKOS000121490, Bis(2-methyl-2-propanyl) dicarbonate, DI-TERT-BUTYL DICARBONATE [MI], FD01178, Di-tert-butyl dicarbonate 1.0M in THF, pyrocarbonic acid ditertiary butyl ester, tert-butyl(tert-butoxycarbonyloxy)formate, BP-20551, PD118138, (tert-butoxy)carbonyl (tert-butoxy)formate, CS-0017817, D1547, D3878, D3879, D3880, Di-tert-butyl dicarbonate, >=98.0% (GC), NS00000554, ST51044297, tert-butyl[(tert-butyl)oxycarbonyloxy]formate, EN300-17516, tert-butyl [(tert-butyl)oxycarbonyloxy]formate, BOC anhydride;DIBOC;Di-tert-butyl dicarbonate, C90704, Di-tert-butyl dicarbonate 2.0M in Ethyl acetate, Di-tert-butyl dicarbonate, ReagentPlus(R), 99%, carbonic acid tert-butoxycarbonyl tert-butyl ester, Di-tert-butyl dicarbonate, 2.0M solution in THF, F021896, Q175718, Di-tert-butyl dicarbonate, 1.0 M solution in THF, Di-tert-butyl dicarbonate, ReagentPlus(R), >=99%, Dicarbonic acid, 1,3-bis(1,1-dimethylethyl) ester, (2-Methylpropan-2-yl)oxycarbonyl tert-butyl carbonate, F0001-0830, DICARBONIC ACID C,C'-BIS(1,1-DIMETHYLETHYL) ESTER
Theoretical properties:
molecular_formula: C10H18O5
molecular_weight: 218.25 g/mol
exact_mass: 218.11542367 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 6
heavy_atom_count: 15
topological_polar_surface_area: 61.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Tert-butoxycarbonyl anhydride is an acyclic carboxylic anhydride. It is functionally related to a dicarbonic acid.
wikipedia: Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. Since this compound can be regarded formally as the acid anhydride derived from a tert-butoxycarbonyl (Boc) group, it is commonly referred to as Boc anhydride. This pyrocarbonate reacts with amines to give N-tert-butoxycarbonyl or so-called Boc derivatives. These carbamate derivatives do not behave as amines, which allows certain subsequent transformations to occur that would be incompatible with the amine functional group. The Boc group can later be removed from the amine using moderately strong acids (e.g., trifluoroacetic acid). Thus, Boc serves as a protective group, for instance in solid phase peptide synthesis. Boc-protected amines are unreactive to most bases and nucleophiles, allowing for the use of the fluorenylmethyloxycarbonyl group (Fmoc) as an orthogonal protecting group.