Compound: ketoprofen
SMILES: O=C(c1cc(ccc1)C(C(=O)O)C)c2ccccc2
InChIKey: DKYWVDODHFEZIM-UHFFFAOYSA-N
Synonyms: ketoprofen, 22071-15-4, 2-(3-Benzoylphenyl)propanoic acid, 2-(3-Benzoylphenyl)propionic acid, Orudis, Oruvail, Capisten, Actron, Alrheumat, Ketoprofene, Aneol, m-Benzoylhydratropic acid, 3-Benzoylhydratropic acid, Iso-K, Ketoprofeno, Orudis KT, RP-19583, Sector, Ketoprofenum, Ketorin, (rs)-ketoprofen, Actron ketoprofen, 3-BENZOYL-ALPHA-METHYLBENZENEACETIC ACID, DTXSID6020771, Benzeneacetic acid, 3-benzoyl-alpha-methyl-, Hydratropic acid, m-benzoyl-, NSC-758144, 19583RP, NEXCEDE, CHEBI:6128, IDEA-033, 90Y4QC304K, R.P. 19,583, RU-4733, DTXCID40771, R.P. 19583, (2RS)-2-(3-Benzoylphenyl)propanoic acid, Benzoylhydratropic Acid, RP19583, ketonal, Ketofen, Ketovail, Kiprofen, Larafen, Powergel, Tiloket, Axorid, KetoMed, Jomethid xl, Larafen cr, Oruvail im, Tiloket cr, RP, 19,583, Ketotard 200 xl, Ketozip 200 xl, Fenoket 200, Ketocid 200, KETOPHENE, Oruvail 100, Oruvail 150, Oruvail 200, Valket 200 retard, Orudis 100, RefChem:5933, M01AE03, M02AA10, 244-759-8, Alrheumun, Profenid, Epatec, Orudis (TN), Ketoprophene, 2-(m-Benzoylphenyl)propionic acid, rac Ketoprofen, Racemic ketoprofen, 2-[3-(phenylcarbonyl)phenyl]propanoic acid, Benzeneacetic acid, 3-benzoyl-.alpha.-methyl-, RU 4733, MFCD00055790, CHEMBL571, Propionic acid, 2-(3-benzoylphenyl)-, 19583 RP, MLS000079024, Kefenid, Menamin, Lertus, 1189508-77-7, Ketopron, Meprofen, Orugesic, Oscorel, SMR000040181, Fastum, Ketoprofen 100 microg/mL in Acetonitrile, Toprec, Toprek, Dexal, racemic-Ketoprofen, RP 19583, Ketoprofene [INN-French], Ketoprofenum [INN-Latin], Ketoprofeno [INN-Spanish], Ketoprofen (+-), Ketoprofen (Actron), (+-)-m-Benzoylhydratropic acid, (S)-Ketoprofen;Dexketoprofen, SR-01000075949, Alrheumat;, CCRIS 4508, Oruvail;, Ketoprofen CRS, Orudis;, (+-)-3-Benzoyl-alpha-methylbenzeneacetic acid, (+) ketoprofen, NCGC00016757-01, Acide (benzoyl-3-phenyl)-2-propionique [French], Prestwick_617, EINECS 244-759-8, 2-[3-(benzoyl)phenyl]propanoic acid, CAS-22071-15-4, Ketoprofen (Standard), 2-(3-benzoylphenyl)-propionic acid, Hydratropic acid, m-benzoyl-, (+-)-, Acide (benzoyl-3-phenyl)-2-propionique, Spectrum_001309, KETOPROFEN [MI], Opera_ID_509, L'Acide (benzoyl-3-phenyl)-2-propionique, KETOPROFEN [INN], KETOPROFEN [JAN], Prestwick0_000219, Prestwick1_000219, Prestwick2_000219, Prestwick3_000219, Spectrum2_000956, Spectrum3_001479, Spectrum4_000028, Spectrum5_001254, KETOPROFEN [USAN], m-benzoyl-hydratropic acid, KETOPROFEN [VANDF], Epitope ID:131783, K 1751, KETOPROFEN [MART.], SCHEMBL2896, KETOPROFEN [WHO-DD], (+/-)-KETOPROFEN, Lopac0_000686, Oprea1_117113, BSPBio_000237, BSPBio_003037, KBioGR_000435, KBioSS_001789, 22161-86-0, MLS000028446, MLS001201752, MLS001306444, MLS002548889, MLS006011967, BIDD:GT0443, DivK1c_000598, SCHEMBL679920, SPECTRUM1501215, UNII-90Y4QC304K, SPBio_000952, SPBio_002158, Benzeneacetic acid, 3-benzoyl-alpha-methyl-, (+-)-, BPBio1_000261, GTPL4795, Ketoprofen (JP18/USP/INN), Ketoprofen - Bio-X trade mark, orb1310246, orb3139754, KETOPROFEN [GREEN BOOK], Ketoprofen, >=98% (TLC), (2S)-2-(3-Benzoylphenyl)(3-~13~C,3,3,3-~2~H_3_)propanoic acid, KETOPROFEN [EP IMPURITY], KETOPROFEN [ORANGE BOOK], DKYWVDODHFEZIM-UHFFFAOYSA-, HMS501N20, HY-B0227R, KBio1_000598, KBio2_001789, KBio2_004357, KBio2_006925, KBio3_002537, 2-(3-Benzoylphenyl)propanoicacid, KETOPROFEN [EP MONOGRAPH], KETOPROFEN [USP IMPURITY], MSK7153, (+/-)-m-Benzoylhydratropic acid, NINDS_000598, GLXC-07776, HMS1568L19, HMS1921B12, HMS2089B16, HMS2092L19, HMS2095L19, HMS2234H16, HMS3259I05, HMS3262I13, HMS3372M08, HMS3373G09, HMS3649N10, HMS3655C15, HMS3712L19, HMS3884K04, HMS5079F06, HMS5086B22, KETOPROFEN [USP MONOGRAPH], Pharmakon1600-01501215, HY-B0227, 2-(3'-benzoylphenyl)propionic acid, 2-(3-benzoyl-phenyl)propionic acid, 2-(3-benzoylphenyl) propionic acid, alpha(3-benzoylphenyl)propionic acid, Tox21_110594, Tox21_200847, Tox21_500686, (.+/-.)-m-Benzoylhydratropic acid, 2-(3-benzoylphenyl) propionoic acid, alpha-(m-benzoylphenyl)propionic acid, BDBM50022271, CCG-39685, EBC-06731, MSK7153-100A, NSC758144, s1645, SBB063946, STL450995, 2-(3-Benzoylphenyl)propanoic acid #, 3-benzoyl-a-methyl-benzeneacetic acid, alpha-(3-benzoylphenyl)propionic acid, AKOS007930512, alpha-(m-benzoylphenyl) propionic acid, MSK7153-1000A, Tox21_110594_1, AC-1486, DB01009, FK15499, Ketoprofen [USAN:USP:INN:BAN:JAN], KS-5031, LP00686, NC00459, NSC 758144, SDCCGSBI-0050664.P004, IDI1_000598, NCGC00015578-02, NCGC00015578-03, NCGC00015578-04, NCGC00015578-05, NCGC00015578-07, NCGC00015578-08, NCGC00015578-10, NCGC00015578-12, NCGC00015578-23, NCGC00094043-01, NCGC00094043-02, NCGC00094043-03, NCGC00094043-04, NCGC00258401-01, NCGC00261371-01, BK166172, 3-Benzoyl-.alpha.-methylbenzeneacetic acid, SBI-0050664.P003, (+/-)-2-(3-Benzoylphenyl)propionic acid, Ketoprofen 1000 microg/mL in Acetonitrile, L''Acide (benzoyl-3-phenyl)-2-propionique, UNM-0000306100, AB00052249, EU-0100686, K0038, Ketoprofen, meets USP testing specifications, NS00000216, SW196784-3, BIM-0050664.0001, C01716, D00132, D78110, EN300-120644, Ketoprofen Solution in Acetonitrile, 100ug/mL, Ketoprofen, VETRANAL(TM), analytical standard, (S)-(+)-3-Benzoyl-alpha-methylbenzeneacetic 5, AB00052249-17, AB00052249-19, AB00052249-20, AB00052249_21, AB00052249_22, Ketoprofen Solution in Acetonitrile, 1000ug/mL, F078938, Q409192, SR-01000075949-1, SR-01000075949-6, SR-01000075949-9, (.+/-.)-3-Benzoyl-.alpha.-methylbenzeneacetic acid, BRD-A97739905-001-05-9, BRD-A97739905-001-15-8, BRD-A97739905-001-25-7, BRD-A97739905-001-26-5, SR-01000075949-18, F2173-0960, Z1530532758, (+/-)-3-BENZOYL-.ALPHA.-METHYLBENZENEACETIC ACID, Ketoprofen, British Pharmacopoeia (BP) Reference Standard, Ketoprofen, European Pharmacopoeia (EP) Reference Standard, Ketoprofen, United States Pharmacopeia (USP) Reference Standard, Ketoprofen, Pharmaceutical Secondary Standard; Certified Reference Material, 154907-35-4, InChI=1/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
Theoretical properties:
molecular_formula: C16H14O3
molecular_weight: 254.28 g/mol
exact_mass: 254.094294304 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 4
heavy_atom_count: 19
topological_polar_surface_area: 54.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Ketoprofen is an oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2. It has a role as a non-steroidal anti-inflammatory drug, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a xenobiotic, an environmental contaminant and a drug allergen. It is a member of benzophenones and an oxo monocarboxylic acid. It is functionally related to a propionic acid.
chebi: An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.
chembl: KETOPROFEN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin.
It was patented in 1967 and approved for medical use in 1980.