Compound: KALLIDIN
SMILES: O=C(N1[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCN=C(N)N)Cc3ccccc3)CCC2)CO)Cc4ccccc4)CCC1)[C@H]5N(C(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)CCCN=C(N)N)CCC5
InChIKey: FYSKZKQBTVLYEQ-FSLKYBNLSA-N
Synonyms: KALLIDIN, Lys-Bradykinin, 342-10-9, Lysyl-bradykinin, kallidin II, Bradykinin, Lysine, Bradykinin, N2-L-lysyl-, (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid, DTXSID40895018, 0T8T4A440G, N2-L-Lysylbradykinin, Lys Bradykinin, Lysyl Bradykinin, Lysine Bradykinin, Bradykinin, Lysyl, (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-guanidino-pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-3-hydroxy-propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propanoyl]amino]-5-guanidino-pentanoic acid, N2 L Lysylbradykinin, Tetraacetate, Kallidin, (2S)-2-(((2S)-2-(((2S)-1-((2S)-2-(((2S)-2-((2-(((2S)-1-((2S)-1-((2S)-2-(((2S)-2,6-diaminohexanoyl)amino)-5-(diaminomethylideneamino)pentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carbonyl)amino)acetyl)amino)-3-phenylpropanoyl)amino)-3-hydroxypropanoyl)pyrrolidine-2-carbonyl)amino)-3-phenylpropanoyl)amino)-5-(diaminomethylideneamino)pentanoic acid, (2S)-2-(((2S)-2-(((2S)-1-((2S)-2-(((2S)-2-((2-(((2S)-1-((2S)-1-((2S)-2-(((2S)-2,6-diaminohexanoyl)amino)-5-guanidino-pentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carbonyl)amino)acetyl)amino)-3-phenyl-propanoyl)amino)-3-hydroxy-propanoyl)pyrrolidine-2-carbonyl)amino)-3-phenyl-propanoyl)amino)-5-guanidino-pentanoic acid, RefChem:150874, DTXCID501324577, 206-438-0, Lysylbradykinin, [Lys]bradykinin, Lys-BK, 2-[[2-[[1-[2-[[2-[[2-[[1-[1-[2-(2,6-diaminohexanoylamino)-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid, C56H85N17O12, UNII-0T8T4A440G, FYSKZKQBTVLYEQ-FSLKYBNLSA-N, EINECS 206-438-0, GTPL650, SCHEMBL150645, CHEBI:6102, orb1679117, CHEMBL5665421, SCHEMBL30526215, AKOS024457492, MS-32996, HY-103293, CS-0027229, C01505, Q2398786, L-Lysyl-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine
Theoretical properties:
molecular_formula: C56H85N17O12
molecular_weight: 1188.4 g/mol
exact_mass: 1187.65636121 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 14
hydrogen_bond_acceptor_count: 16
rotatable_bond_count: 33
heavy_atom_count: 85
topological_polar_surface_area: 474 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Kallidin is a peptide.
chembl: Unnamed Compound is a unknown type listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Kallidin belongs to the family kinins, which are the peptide hormones. Kallidin is a decapeptide whose sequence is H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. Removal of the N-terminal lysine by Factor XII, or to a leser extent aminopeptidase yields the potently bioactive bradykinin molecule.