Compound: tetracaine
SMILES: O=C(OCCN(C)C)c1ccc(NCCCC)cc1
InChIKey: GKCBAIGFKIBETG-UHFFFAOYSA-N
Synonyms: tetracaine, 94-24-6, Amethocaine, 2-(Dimethylamino)ethyl 4-(butylamino)benzoate, Laudocaine, Metraspray, Pontocaine, Anetain, Dicaine, Uromucaesthin, Contralgin, Fissucain, Intercain, Medicaine, Meethobalm, Mucaesthin, Niphanoid, Medihaler-Tetracaine, Tetracaina, Tetrakain, Dicain, Dikain, Tetracainum, 2-(Dimethylamino)ethyl p-(butylamino)benzoate, p-Butylaminobenzoyl-2-dimethylaminoethanol, Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, Diaethylaminoaethanol ester der p-butylaminobenzoesaeure, CHEBI:9468, 0619F35CGV, DTXSID1043883, p-(butylamino)benzoic acid beta-(dimethylamino)ethyl ester, Tetracaine cream, FranklyNumb 3, Painless Tattoo 3, Burn Solution Cream, RefChem:56112, Numfast Tetracaine Green, Hydrochloride, Tetrracaine, BLT 3, DTXCID9023883, dicainum (for the hydrochloride), C05AD02, D04AB06, N01BA03, S01HA03, 202-316-6, Rexocaine, Dimethylaminoethyl p-butyl-aminobenzoate, 2-dimethylaminoethyl 4-(butylamino)benzoate, MFCD00053787, 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Butylocaine, p-(Butylamino)benzoic acid, 2-(dimethylamino)ethyl ester, CHEMBL698, BENZOIC ACID, p-(BUTYLAMINO)-, 2-(DIMETHYLAMINO)ETHYL ESTER, 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove, Tetrakain [Czech], Tetracainum [INN-Latin], Tetracaina [INN-Spanish], benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester ,hydrochloride, Amethocaine (TN), Tetracaine (USP/INN), NCGC00016049-02, CAS-136-47-0, EINECS 202-316-6, BRN 2216051, Landocaine, Tetracain, Tetracaine [USP:INN:BAN], UNII-0619F35CGV, Amethocaine HCl, Tetracaine CRS, 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove [Czech], Diaethylaminoaethanol ester der p-butylaminobenzoesaeure [German], TE4, Spectrum_001032, Pantocaine (Salt/Mix), TETRACAINE [INN], Prestwick0_000571, Prestwick1_000571, Prestwick2_000571, Prestwick3_000571, Spectrum2_001328, Spectrum3_000562, Spectrum4_000351, Spectrum5_001072, Lopac-T-7508, TETRACAINE [VANDF], Epitope ID:174843, TETRACAINE [MART.], TETRACAINE [USP-RS], TETRACAINE [WHO-DD], Lopac0_001211, SCHEMBL34714, BSPBio_000382, BSPBio_001944, KBioGR_000781, KBioSS_001512, 4-14-00-01172 (Beilstein Handbook Reference), DivK1c_000607, SPBio_001455, SPBio_002601, BPBio1_000422, TETRACAINE [GREEN BOOK], Tetracaine, >=98% (TLC), TETRACAINE [ORANGE BOOK], KBio1_000607, KBio2_001512, KBio2_004080, KBio2_006648, KBio3_001444, TETRACAINE [EP MONOGRAPH], NINDS_000607, SYNERA COMPONENT TETRACAINE, TETRACAINE [USP MONOGRAPH], ALBB-025902, HY-A0079, MSK10139, BDBM50017659, EBC-12624, SBB058194, STL483844, AKOS015889234, AC-3480, CCG-205285, DB09085, SDCCGSBI-0051178.P005, IDI1_000607, NCGC00016049-01, NCGC00016049-03, NCGC00016049-04, NCGC00016049-14, NCGC00162367-01, AS-81743, DA-78348, FT177996, ST099115, SY066710, SBI-0051178.P004, AB00053549, NS00008930, T2789, Tetracaine, meets USP testing specifications, .beta.-Dimethylaminoethyl p-butylaminobenzoate, C07526, D00551, 2-(Dimethylamino)ethyl 4-(butylamino)benzoate #, AB00053549-11, AB00053549_12, AB00053549_13, EN300-6748839, Q419608, aniline, N-butyl-4-(2-dimethylaminoethoxycarbonyl)-, BRD-K45071273-003-05-8, BRD-K45071273-003-15-7, BRD-K45071273-003-24-9, BRD-K45071273-003-25-6, Tetracaine, United States Pharmacopeia (USP) Reference Standard, BENZOIC ACID,4-BUTYLAMINO,2-DIMETHYLAMINOETHYL ESTER   PANTOCAIN BASE, InChI=1/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3/h6-9,16H,4-5,10-12H2,1-3H
Theoretical properties:
molecular_formula: C15H24N2O2
molecular_weight: 264.36 g/mol
exact_mass: 264.183778013 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 9
heavy_atom_count: 19
topological_polar_surface_area: 41.6 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Tetracaine is a benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia. It has a role as a local anaesthetic. It is a benzoate ester and a tertiary amino compound.
chebi: A benzoate ester in which 4-<em>N</em>-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.
chembl: TETRACAINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Tetracaine, also known as amethocaine, is an ester local anesthetic used to numb the eyes, nose, or throat. It may also be applied to the skin before starting intravenous therapy to decrease pain from the procedure. Typically it is applied as a liquid to the area. Onset of effects when used in the eyes is within 30 seconds and last for less than 15 minutes.
Common side effects include a brief period of burning at the site of use. Allergic reactions may uncommonly occur. Long-term use is generally not recommended as it may slow healing of the eye. It is unclear if use during pregnancy is safe for the baby. Tetracaine is in the ester-type local anesthetic family of medications. It works by blocking the sending of nerve impulses.
Tetracaine was patented in 1930 and came into medical use in 1941. It is on the World Health Organization's List of Essential Medicines