Compound: naphazoline
SMILES: N1=C(NCC1)Cc2c3c(ccc2)cccc3
InChIKey: CNIIGCLFLJGOGP-UHFFFAOYSA-N
Synonyms: naphazoline, 835-31-4, 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole, Nafazolina, Clearine, Nafazolin, Naphazolinum, 2-(1-Naphthylmethyl)-2-imidazoline, Ciba 2020/R, alpha-Naphthylmethyl imidazoline, 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, H231GF11BV, DTXSID3048449, DTXCID90198485, Tele Stulln, AK Con, Vasoconstrictor Pensa, Pensa, Vasoconstrictor, RefChem:56335, naphthizinum (for the nitrate), R01AA08, R01AB02, S01GA01, 212-641-5, Naphthizine, Antan, 2-(1-Naphthylmethyl)-4,5-dihydro-1H-imidazole, 2-(Naphthyl-(1')-methyl)imidazolin, Naphazoline (INN), 2-Imidazoline, 2-(1-naphthylmethyl)-, 2-[(naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole, Naphazoline (hydrochloride), Nafazolina [DCIT], NCGC00024349-03, Nafazoline, Nafazoline [Spanish], Naphazolinum [Latin], NAPHAZOLINE [INN], Naphazoline [INN:BAN], Naphazolinum [INN-Latin], Rhinazine, CHEMBL1706, 2-(alpha-Naphthylmethyl)-imidazoline, CAS-835-31-4, 4,5-Dihydro-2-(1-naphthylmethyl)imidazole, Enamine_000333, 10061-11-7, 2-(Naphthyl-(1')-methyl)imidazolin [German], CAS-550-99-2, EINECS 212-641-5, BRN 0151864, UNII-H231GF11BV, Imidin, Privine (Salt/Mix), Sanorin (Salt/Mix), Spectrum_000975, NAPHAZOLINE [MI], Prestwick0_000046, Prestwick1_000046, Prestwick2_000046, Prestwick3_000046, Spectrum2_001054, Spectrum3_000513, Spectrum4_000068, Spectrum5_001424, CHEMBL761, NAPHAZOLINE [VANDF], NAPHAZOLINE [MART.], SCHEMBL34532, BSPBio_000171, BSPBio_002065, KBioGR_000595, KBioSS_001455, NAPHAZOLINE [WHO-DD], 5-23-08-00293 (Beilstein Handbook Reference), AK-968/41090774, cid_11079, DivK1c_000456, SPBio_001008, SPBio_002092, BPBio1_000189, GTPL5509, orb1306358, SCHEMBL29369882, CHEBI:93363, KBio1_000456, KBio2_001455, KBio2_004023, KBio2_006591, KBio3_001565, 2-(naphthylmethyl)-2-imidazoline, NINDS_000456, .alpha.-Naphthylmethyl imidazoline, GLXC-08137, HMS1394P03, HMS2090D15, Tox21_113058, Tox21_113645, BBL012612, BDBM50001922, EBC-06528, MFCD00066737, STK300042, AKOS000295230, CCG-250339, DB06711, 2-(.alpha.-Naphthylmethyl)-imidazoline, 2-(1-Naphthalenylmethyl)-2-imidazoline, IDI1_000456, NCGC00016506-01, NCGC00016506-02, NCGC00016506-03, NCGC00016506-04, NCGC00016506-05, VS-03410, SBI-0051454.P003, DB-050155, HY-111326, CS-0034952, NS00003424, ST45061546, EN300-16752, D08253, G77792, AB00053505-11, AB00053505-12, AB00053505_13, AB00053505_14, L000878, Q415433, 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole, 2-(1-Naphthylmethyl)-4,5-dihydro-1H-imidazole #, BRD-K77641333-003-05-7, BRD-K77641333-003-15-6, BRD-K77641333-003-25-5, BRD-K77641333-003-26-3, BRD-K77641333-003-27-1, Z56762888, 2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride
Theoretical properties:
molecular_formula: C14H14N2
molecular_weight: 210.27 g/mol
exact_mass: 210.115698455 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 2
heavy_atom_count: 16
topological_polar_surface_area: 24.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole is a member of naphthalenes.
chembl: NAPHAZOLINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Naphazoline is a medicine used as a decongestant, and a vasoconstrictor added to eye drops to relieve red eye. It has a rapid action in reducing swelling when applied to mucous membranes. It is a sympathomimetic agent with marked alpha adrenergic activity that acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. 
It was patented in 1934 and came into medical use in 1942.