Compound: Propamidine
SMILES: O(c1ccc(C(=N)N)cc1)CCCOc2ccc(C(=N)N)cc2
InChIKey: WTFXJFJYEJZMFO-UHFFFAOYSA-N
Synonyms: Propamidine, 104-32-5, Propamidina, Propamidinum, 4,4'-(Trimethylenedioxy)dibenzamidine, M&B 782 FREE BASE, M&B-782 FREE BASE, DTXSID6048674, 4,4'-(1,3-Propanediylbis(oxy))bis-benzenecarboximidamide, G20G12V769, DTXCID6028600, CHEBI:87462, DAPP-H, 1,3-bis(p-amidinophenoxy)propane, 1,3-di-(4-amidinophenoxy)propane, 1,3-di-(p-amidinophenoxymethyl)-propane, RefChem:176252, D08AC03, S01AX15, 4-(3-(4-carbamimidoylphenoxy)propoxy)benzene-1-carboximidamide, 203-195-2, Benzenecarboximidamide, 4,4'-[1,3-propanediylbis(oxy)]bis-, 1,3-BIS(AMIDINOPHENOXY)PROPANE, Propamide dihydrochloride, 4-[3-(4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide, GNF-PF-3839, Propamidine (INN), NCGC00183108-01, PROPAMIDINE [INN], 4,4'-(propane-1,3-diylbis(oxy))dibenzimidamide, 4-[3-(4-carbamimidoylphenoxy)propoxy]benzamidine, Panamidin, 4,4'-[propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide), 4,4'-Diamidino-1,3-diphenoxypropane dihydrochloride, Propamidinum [INN-Latin], Propamidina [INN-Spanish], Propamidine [INN:BAN:DCF], NSC33297, EINECS 203-195-2, UNII-G20G12V769, PROPAMIDINE [MI], GlyTouCan:G39176VO, PROPAMIDINE CHLORIDE, PROPAMIDINE [WHO-DD], CHEMBL23013, SCHEMBL231060, orb1944504, G39176VO, Tox21_113051, BDBM50368092, M&B 782 [AS ISETHIONATE], AKOS015854464, DB13296, HY-130402B, p,p'-(Trimethylenedioxy)dibenzamidine-, CAS-104-32-5, FP151543, CS-0119541, NS00041349, 4,4'-(TRIMETHYLEDEDIOXY)DIBENZAMIDINE, D07205, Q1240692, 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide, 4,4'-[1,3-Propanediylbis(oxy)]bisbenzenecarboximidamide-, 4,4'-(1,3-PROPANEDIYLBIS(OXY)BIS(BENZENECARBOXIMIDAMIDE), 4-(3-(4-(Amino(imino)methyl)phenoxy)propoxy)benzenecarboximidamide, Benzenecarboximidamide, {4,4'-[1,3-propanediylbis(oxy)]bis-,} dihydrochloride
Theoretical properties:
molecular_formula: C17H20N4O2
molecular_weight: 312.37 g/mol
exact_mass: 312.15862589 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 8
heavy_atom_count: 23
topological_polar_surface_area: 118 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Propamidine is a polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. It has a role as an antimicrobial agent and an antiseptic drug. It is a member of guanidines, an aromatic ether and a polyether. It is functionally related to a propane-1,3-diol. It is a conjugate base of a propamidine(2+).
chebi: A polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis.
chembl: PROPAMIDINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Propamidine is an antiseptic and disinfectant.
Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection.
Propamidine is a member of the aromatic diamidine group of compounds which possess bacteriostatic properties against a wide range of organisms.   These diamidines exert antibacterial action against pyrogenic cocci, antibiotic resistant staphylococci and some Gram-negative bacilli, the activity of the diamidines being retained in the presence of organic matter such as tissue fluids, pus and serum.