Compound: Butyrfentanyl
SMILES: O=C(N(c1ccccc1)C2CCN(CCc3ccccc3)CC2)CCC
InChIKey: QQOMYEQLWQJRKK-UHFFFAOYSA-N
Synonyms: Butyrfentanyl, Butyr-fentanyl, 1169-70-6, Butyryl fentanyl, Butyryl-fentanyl, 07V1H7R6ZN, N-(1-Phenethylpiperidin-4-yl)-N-phenylbutyramide, N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)butanamide, NIH-10486 FREE BASE, DTXSID30347410, N-(1-phenylethyl)-4-piperidinyl)-N-phenylbutyramide, N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]butanamide, RefChem:571886, DTXCID20298482, Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, Butyrylfentanyl, BUTYRLFENTANYL, N-PHENYL-N-[1-(2-PHENYLETHYL)PIPERIDIN-4-YL]BUTANAMIDE, UNII-07V1H7R6ZN, CHEBI:233557, N-(1-phenethylpiperidin-4-yl)-N-phenylbutanamide, DEA No. 9822, Butyrfentanyl (Butyrylfentanyl), Methyl-3-fentanyl, BUTANAMIDE, N-PHENYL-N-(1-(2-PHENYLETHYL)-4-PIPERIDINYL)-, Butyranilide, N-(1-phenethyl-4-piperidyl)- (7CI,8CI); N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]butanamide; Butyryl Fentanyl; Butyrfentanyl; Butyrylfentanyl; N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide, N-BUTYRYLFENTANYL, N-butyramide fentanyl analog, Epitope ID:2272248, N-Phenyl-N-(1-phenethyl-4-piperidinyl)butanamide, CHEMBL4759342, SCHEMBL18623773, QQOMYEQLWQJRKK-UHFFFAOYSA-N, BDBM641072, CS-D0505, Butyrylfentanyl, 1mg/ml in Methanol, AKOS025243418, DB09173, N-(1-phenethyl-4-piperidyl)butyranilide, AS-48590, DB-027083, NS00017195, US20230399418, Compound Butyrylfentanyl, C22760, Q15408419, 1-(2-phenylethyl)-4-(N,N-butyrylphenylamino)piperidine, N-(1-PHENETHYL-4-PIPERIDYL)-N-PHENYL-BUTANAMIDE, N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]butanamide #
Theoretical properties:
molecular_formula: C23H30N2O
molecular_weight: 350.5 g/mol
exact_mass: 350.235813585 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 7
heavy_atom_count: 26
topological_polar_surface_area: 23.6 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Butyrfentanyl is a monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with butanoic acid. It is a fentanyl analog that is used as a recreational drug. It has a role as an opioid analgesic and a mu-opioid receptor agonist. It is an anilide, a member of piperidines, a monocarboxylic acid amide and a tertiary amino compound.
chebi: A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of <em>N</em>-phenyl-1-(2-phenylethyl)piperidin-4-amine with butanoic acid. It is a fentanyl analog that is used as a recreational drug.
chembl: Unnamed Compound is a unknown listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Butyrfentanyl or butyrylfentanyl is a potent short-acting synthetic opioid analgesic drug.  It is an analog of fentanyl with around one quarter of its potency. One of the first mentions of this drug can be found in document written by The College on Problem of Drug Dependence, where it is mentioned as N-butyramide fentanyl analog. This document also states that the article describing its clinical effects (analgesic studies, μ-, δ-, κ-opioid receptor binding, and in vitro measures of drug efficacy, antinociceptive, and narcotic properties) was published in 1987. It is an agonist for the μ-opioid receptors.
Butyrfentanyl has no current legitimate clinical applications; however, it is being sold as a designer drug.
Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea, and potentially serious respiratory depression which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.