Compound: butabarbital
SMILES: O=C1NC(=O)C(C(CC)C)(CC)C(N1)=O
InChIKey: ZRIHAIZYIMGOAB-UHFFFAOYSA-N
Synonyms: butabarbital, Secbutabarbital, Secbutobarbitone, Butatab, Butisol, Butabarbitone, Secbubarbital, Medarsed, Unicelles, Nilox, Butrate, Butatal, sec-Butobarbitone, 125-40-6, 5-sec-Butyl-5-ethylbarbituric acid, 5-Ethyl-5-(1-methylpropyl)barbituric acid, Secbutabarbitalum, 5-sec-Butyl-5-ethylmalonyl urea, Barbituric acid, 5-sec-butyl-5-ethyl-, Butabarbital ciii, 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylpropyl)-, Butabarbital (USP), 5-Ethyl-5-(1-methylpropyl)barbiturate, 5-Ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, NSC27517, Butabarbital [USP], P0078O25A9, 5-(butan-2-yl)-5-ethyl-1,3-diazinane-2,4,6-trione, 5-Sec-butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-sec-butyl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione, CHEBI:3228, DTXSID2022709, 5-(butan-2-yl)-5-ethyl-4,6-dihydroxy-2,5-dihydropyrimidin-2-one, secumalum, RefChem:917726, DTXCID202709, 204-738-6, Etoval, NSC 27517, Butabarbital (VAN), Secbutobarbital, Secbutabarbitale, Secbutabarbitale [DCIT], Secbutabarbital; Butabarbital, Secbutabarbitalum [INN-Latin], Secbutabarbital [INN], HSDB 3018, WLN: T6VMVMV FHJ FY2 & 1 F2, EINECS 204-738-6, BRN 0199127, UNII-P0078O25A9, Secbutabarbital (BAN), BUTABARBITAL [MI], 5-SEC-BUTYL-5-ETHYL-BARBITURIC ACID, Pyridium plus (Salt/Mix), CHEMBL449, BUTABARBITAL [HSDB], Secbutabarbital [INN:BAN], BUTABARBITAL [VANDF], SCHEMBL79254, GTPL7137, SECBUTABARBITAL [MART.], SCHEMBL22556204, SECBUTABARBITAL [WHO-DD], Butabarbital, 1mg/ml in Methanol, 5-(butan-2-yl)-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione, BUTABARBITAL [USP IMPURITY], BUTABARBITAL CIII [USP-RS], 5-ethyl-5-(1-methylpropyl)pyrimidine-2,4,6(1H,3H,5H)-trione, QYB56564, BUTABARBITAL [USP MONOGRAPH], HY-U00167, NSC-27517, AKOS015962208, CS-7224, DB00237, AC-16078, NS00008671, C07827, D03180, Q410608, 5-Sec-butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione #, 2,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylpropyl)-
Theoretical properties:
molecular_formula: C10H16N2O3
molecular_weight: 212.25 g/mol
exact_mass: 212.11609238 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 3
heavy_atom_count: 15
topological_polar_surface_area: 75.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Fine, white, microcrystalline powder
color: Fine, white, microcrystalline powder
odor: Odorless
solubility: WHITE POWDER; PRACTICALLY INSOL IN BENZENE & ABS ETHER /SODIUM SALT/
Descriptions:
pubchem: Butabarbital is a member of barbiturates.
chembl: BUTABARBITAL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Butabarbital (brand name Butisol) is a prescription barbiturate sleep aid and anxiety medication. Butabarbital has a particularly fast onset of effects and short duration of action compared to other barbiturates, which makes it useful for certain applications such as treating severe insomnia, relieving general anxiety and relieving anxiety before surgical procedures; however it is also relatively dangerous particularly when combined with alcohol, and so is now rarely used, although it is still prescribed in some Eastern European and South American countries. Its intermediate duration of action gives butabarbital an abuse potential slightly lower than secobarbital. Butabarbital can be hydrolyzed to valnoctamide.

Butabarbital is also sold in combination with belladonna alkaloids under the brand name Butibel. The belladonna is added for antispasmodic effect. This product contains a low dose of butabarbital combined with a standardised mix of belladonna alkaloids and is used as an antispasmodic taken to relieve cramping and spasms of the stomach and intestines. They are used also to decrease the amount of acid formed in the stomach. Another similar product is Donnatal, which contains belladonna alkaloids combined with phenobarbital.