Compound: Butriptyline
SMILES: N(CC(CC1c2c(cccc2)CCc3c1cccc3)C)(C)C
InChIKey: ALELTFCQZDXAMQ-UHFFFAOYSA-N
Synonyms: Butriptyline, 35941-65-2, Butriptylene, Butriptilina, Butriptylinum, DTXSID6022715, DTXCID902715, Z22441975X, 10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo(a,d)cycloheptene-5-propylamine, 10,11-dihydro-N,N,beta-trimethyl-5H-dibenzo(a,d) cycloheptane-5-propylamine, AY-2014, RefChem:122190, N06AA15, Evadyne, 15686-37-0, AY 62014, Butriptyline (INN), N,N,2-trimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)propan-1-amine, BUTRIPTYLINE [INN], (.+-.)-Evadyne, Butriptylene hydrochloride, Butriptyline [INN:BAN], Butriptylinum [INN-Latin], Butriptilina [INN-Spanish], AY 2014, BRN 2814611, 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N,2-trimethylpropan-1-amine, Butriptylene;10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo[ed]cycloheptene-5-propanamine, UNII-Z22441975X, Evadyne (TN), Evadene (Salt/Mix), Evadyne (Salt/Mix), Evasidol (Salt/Mix), Butriptyline Free Base, BUTRIPTYLINE [MI], d,l-10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo(a,d)-cycloheptene-5-propylamine, SCHEMBL49089, BUTRIPTYLINE [WHO-DD], orb1941966, CHEMBL2110816, SCHEMBL29847367, BDBM85220, ALELTFCQZDXAMQ-UHFFFAOYSA-N, CHEBI:135227, HY-A0175, Tox21_113980, Butriptyline hydrochloride (Salt/Mix), DB09016, 5H-Dibenzo(a,d)cycloheptene-5-propanamine, 10-11-dihydro-N,N,beta-trimethyl-, (+-)-, NCGC00274277-01, DA-71822, CAS-35941-65-2, CAS_15686-37-0, CS-0017516, NS00009948, D07601, Q904524, (+/-)-3-(10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-yl)-N,N,2-trimethylpropan-1-amine, 10,11-Dihydro-N,N,.beta.-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine, 10,11-Dihydro-N,N,.beta.-trimethyl-5H-dibenzo[ed]cycloheptene-5-propanamine, 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-N,N,2-trimethyl-1-propanamine #, 3-(6,11-dihydro-5H-dibenzo[[?],[?]][7]annulen-11-yl)-N,N,2-trimethyl-propan-1-amine, 5H-Dibenzo(a,d)cycloheptene-5-propanamine, 10-11-dihydro-N,N,.beta.-trimethyl-, (.+/-.)-, Butriptylene;10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[ed]cycloheptene-5-propanamine, d,l-10,11-Dihydro-N,N,.beta.-trimethyl-5H-dibenzo(a,d)-cycloheptene-5-propylamine, (+/-)-10,11-DIHYDRO-N,N,.BETA.-TRIMETHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-5-PROPYLAMINE, 5H-DIBENZO(A,D)CYCLOHEPTENE-5-PROPANAMINE, 10,11-DIHYDRO-N,N,.BETA.-TRIMETHYL-, (+/-)-, 5H-Dibenzo[a,d]cycloheptene-5-propanamine, 10,11-dihydro-N,N,.beta.-trimethyl-, hydrochloride, (.+-.)-, 5H-Dibenzo[a,d]cycloheptene-5-propanamine, 10,11-dihydro-N,N,ss-trimethyl-; 5H-Dibenzo[a,d]cycloheptene-5-propanamine, 10,11-dihydro-N,N,ss-trimethyl-, (+/-)-; 10,11-Dihydro-N,N,ss-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine; 10,11-Dihydro-N,N,ss-trimethyl-5H-dibenzo[ed]cycloheptene-5-propanamine; Butriptylene; Butriptyline
Theoretical properties:
molecular_formula: C21H27N
molecular_weight: 293.4 g/mol
exact_mass: 293.214349865 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 4
heavy_atom_count: 22
topological_polar_surface_area: 3.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Butriptyline is an organic tricyclic compound.
chembl: BUTRIPTYLINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed. Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or "second-generation" TCA due to its relatively late introduction and atypical pharmacology. It was very little-used compared to other TCAs, with the number of prescriptions dispensed only in the thousands.