Compound: N-ethylmaleimide
SMILES: O=C1N(C(=O)C=C1)CC
InChIKey: HDFGOPSGAURCEO-UHFFFAOYSA-N
Synonyms: N-ethylmaleimide, 128-53-0, ethylmaleimide, 1H-pyrrole-2,5-dione, 1-ethyl-, 1-ethylpyrrole-2,5-dione, maleimide, N-ethyl-, maleic acid N-ethylimide, O3C74ACM9V, DTXSID1059573, NSC-7638, CHEBI:44485, N Ethylmaleimide, RefChem:139181, DTXCID4033897, 204-892-4, 1-Ethyl-1H-pyrrole-2,5-dione, NEM, USAF B-121, N-ethyl maleimide, MFCD00005509, n-ethylmaleimide (nem), CHEMBL8211, 25668-22-8, N-Ethyl Maleimide (1M Solution in Acetonitrile), NSC 7638, EINECS 204-892-4, UNII-O3C74ACM9V, BRN 0112448, AI3-50085, N-EM, Lopac-E-3876, 1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione, N-Ethylmaleimide (NIST), ETHYLMALEIMIDE, N-, 1-ethylazoline-2,5-dione, WLN: T5VNVJ B2, 1H-Pyrrole-2, 1-ethyl-, Lopac0_000492, SCHEMBL19666, KBioGR_002548, KBioSS_002557, 5-21-10-00006 (Beilstein Handbook Reference), N-ETHYLMALEIMIDE [MI], SCHEMBL564245, GTPL5335, orb1304555, SCHEMBL9359266, SCHEMBL9777831, KBio2_002548, KBio2_005116, KBio2_007684, KBio3_003026, NSC7638, cMAP_000078, Bio1_000439, Bio1_000928, Bio1_001417, GLXC-20002, HMS3261D05, HMS5081H20, 1-ethyl-3-pyrroline-2,5-quinone, HY-D0843, NSC92547, 1-Ethyl-1H-pyrrole-2,5-dione #, Tox21_500492, BDBM50220832, EBC-46037, GEO-01358, HSCI1_000382, NSC-92547, PI-149, s3692, STK802307, AKOS000249392, AKOS025244114, CCG-204583, DB02967, FE05855, FS-4064, LP00492, SDCCGSBI-0050476.P003, NCGC00015415-01, NCGC00015415-02, NCGC00015415-03, NCGC00015415-04, NCGC00015415-05, NCGC00015415-06, NCGC00093895-01, NCGC00093895-02, NCGC00261177-01, AC-37035, BP-14221, SY045430, DB-041899, CS-0014814, E0136, EU-0100492, N-Ethylmaleimide, BioXtra, >=98% (HPLC), NS00024051, ST51037241, EN300-25478, N-Ethyl Maleimide (1M Solution in Methanol), C02441, E 3876, N-Ethylmaleimide, crystalline, >=98% (HPLC), N-Ethylmaleimide, BioUltra, >=99.0% (HPLC), F047870, Q292393, SR-01000075860, N-Ethylmaleimide, purum p.a., >=99.0% (HPLC), SR-01000075860-1, BRD-K98297262-001-01-1, 4D028806-9A8A-4D25-B355-AEFDEC5AD901, F0001-0396, Z205012234, N-Ethyl Maleimide (1M Solution in Methanol) (DISCONTINUED), InChI=1/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H
Theoretical properties:
molecular_formula: C6H7NO2
molecular_weight: 125.13 g/mol
exact_mass: 125.047678466 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 1
heavy_atom_count: 9
topological_polar_surface_area: 37.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: N-ethylmaleimide is a member of the class of maleimides that is the N-ethyl derivative of maleimide. It has a role as an anticoronaviral agent, an EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor, an EC 2.7.1.1 (hexokinase) inhibitor and an EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor. It is functionally related to a maleimide.
chebi: A member of the class of  maleimides that is the <em>N</em>-ethyl derivative of maleimide.
chembl: N-ETHYLMALEIMIDE is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: N-Ethylmaleimide (NEM) is an organic compound that is derived from maleic acid. It is a unstable substance that reacts rapidly with thiols and is commonly used to modify cysteine residues in proteins and peptides.