Compound: THYMOPENTIN
SMILES: O=C(O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCCN=C(N)N)CCCCN)CC(=O)O)C(C)C)Cc1ccc(O)cc1
InChIKey: PSWFFKRAVBDQEG-YGQNSOCVSA-N
Synonyms: THYMOPENTIN, 69558-55-0, Timunox, Arg-Lys-Asp-Val-Tyr, Sintomodulina, Thymopentine, Timopentina, Thymopoietin 32-36, IMMUNOX, Thymopoietin pentapeptide, DTXSID9046609, Hg-thymopentin, Pentapeptide-1, Oristar thymopentin, Sh-pentapeptide-1, ORF-15244, NSC-760116, Thymopentinum, DTXCID7026609, Thymopoetin 32-36-pentapeptide, ORF 15244, (3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid, Pentapeptide, Thymopoietin, O3Y80ZF13F, NSC645363, L-Tyrosine, N-(N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)-, (3S)-3-(((2S)-6-amino-2-(((2S)-2-amino-5-(diaminomethylideneamino)pentanoyl)amino)hexanoyl)amino)-4-(((2S)-1-(((1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid, RefChem:389322, L03AX09, N-(N-(N-(N(2)-L-Arginyl-L-Lysyl)-L-alpha-Aspartyl)-L-Valyl)-L-Tyrosine, TP-5, MFCD00214200, L-Tyrosine, L-arginyl-L-lysyl-L-a-aspartyl-L-valyl-, (6S,9S,12S,15S,18S)-1,6-diamino-9-(4-aminobutyl)-12-(carboxymethyl)-18-(4-hydroxybenzyl)-1-imino-15-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecan-19-oic acid, C30H49N9O9, Thymopoietin (32-36), Thymopentin Acetate (TP-5), PSWFFKRAVBDQEG-YGQNSOCVSA-N, NCGC00166412-01, TP-5 Acetate, RKDVY, Thymopentin (USAN/INN), SCHEMBL44001, SCHEMBL44002, (3S)-3-[(2S)-6-AMINO-2-[(2S)-2-AMINO-5-CARBAMIMIDAMIDOPENTANAMIDO]HEXANAMIDO]-3-{[(1S)-1-{[(1S)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]CARBAMOYL}-2-METHYLPROPYL]CARBAMOYL}PROPANOIC ACID, MLS000069768, Arg-Lys-Asp-Val-Tyr; RKDVY, CHEMBL156025, Thymopentin, >=97% (HPLC), CHEBI:135870, GLXC-22971, HMS2231E14, HMS3264A15, Pharmakon1600-01506200, HY-N7122, Tox21_112420, EBC-17177, NSC760116, AKOS015994638, CCG-270365, HS-2029, SMP1_000105, SMR000058921, CAS-69558-55-0, CS-0020412, S3668, D06117, Q7799637, BRD-K52097716-001-01-1, L-Arginyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine, (3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-guanidino-pentanoyl]amino]hexanoyl]amino]-4-[[(1S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl]-2-methyl-propyl]amino]-4-oxo-butanoic acid, (6S,9S,12S,15S,18S)-1,6-diamino-9-(4-aminobutyl)-12-(carboxymethyl)-18-(4-hydroxybenzyl)-1-imino-15-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecan-19-oicacid
Theoretical properties:
molecular_formula: C30H49N9O9
molecular_weight: 679.8 g/mol
exact_mass: 679.36532417 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 11
hydrogen_bond_acceptor_count: 12
rotatable_bond_count: 22
heavy_atom_count: 48
topological_polar_surface_area: 328 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Thymopentin is an oligopeptide.
chembl: THYMOPENTIN is a protein listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Thymopentin is a thymic polypeptide derivative which interacts with T cells and acts as an immunostimulant. As such, it was used in several clinical studies in the early years of the AIDS pandemic (from 1983 to 1985). Thymopentin helped to improve immunological condition in some patients for a brief time under specific treatments. It has also been investigated more recently for applications in the treatment of rheumatoid arthritis, and lung cancer.