Compound: ganciclovir
SMILES: O=c1nc([nH]c2c1ncn2COC(CO)CO)N
InChIKey: IRSCQMHQWWYFCW-UHFFFAOYSA-N
Synonyms: ganciclovir, 82410-32-0, Gancyclovir, Vitrasert, Zirgan, BW-759U, Ganciclovirum, RS-21592, BW 759U, Cymevene, Virgan, Cymevan, 2'-Nor-2'-deoxyguanosine, 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine, P9G3CKZ4P5, 9-((1,3-Dihydroxy-2-propoxy)methyl)guanine, NSC-759656, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-one, DTXSID8041032, CHEBI:465284, 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-1H-purin-6-one, 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, DTXCID6021032, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol, 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one, 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one, 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone, 9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine, Nordeoxyguanosine, NSC716361, Ganzyk-rtu, 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6,9-dihydro-3H-purin-6-one, RefChem:922069, 2'NDG, Ganciclovir, Monosodium Salt, J05AB06, S01AD09, 2-Amino-1,9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6H-purin-6-one, Cytovene, Hydroxyacyclovir, 2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1H-purin-6(9H)-one, C9H13N5O4, 2'-NDG, MFCD00870588, Natclovir, 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE, GA2, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one, MLS000028481, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, s1878, NCGC00015471-02, HHEMG, SMR000058324, Biolf 62, Ganciclovirum [Latin], CAS-82410-32-0, 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-3H-purin-6-one, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one, Ganciclovir 100 microg/mL in Acetonitrile:Water, GCV, Citovirax, Cymeven, BW-B 759U, DRG-0018, 2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6,9-dihydro-1H-purin-6-one, Vitrasert (TN), Cytovene (TN), CCRIS 9212, HSDB 6512, SR-01000075894, GCV & MSL, UNII-P9G3CKZ4P5, Ganciclovir (JAN/USP/INN), 2-((2-amino-6-hydroxy-9H-purin-9-yl)methoxy)propane-1,3-diol, 2-[(2-amino-6-hydroxy-9H-purin-9-yl)methoxy]propane-1,3-diol, Ganciclovir CRS, 2-amino-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-1H-purin-6-one, 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1,9-dihydro-6H-purin-6-one, 2-Amino-1,9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6-H-purin-6-one, BW-795, MB3795, Prestwick_1068, ST-605, Zirgan (TN), GCV & 1110U81, Ganciclovir [USAN:USP:INN:BAN:JAN], Ganciclovir (Standard), Opera_ID_284, GANCICLOVIR [MI], Prestwick0_000839, Prestwick1_000839, Prestwick2_000839, Prestwick3_000839, GANCICLOVIR [INN], GANCICLOVIR [JAN], GlyTouCan:G72257IO, Lopac-G-2536, BIOLF62, GANCICLOVIR [HSDB], GANCICLOVIR [USAN], CHEMBL182, EC 627-054-3, G 2536, GANCICLOVIR [VANDF], SCHEMBL3033, SCHEMBL3034, 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one, GANCICLOVIR [MART.], Lopac0_000539, 2'-Nor-2'-deoxyguanosine;, BSPBio_000797, GANCICLOVIR [USP-RS], GANCICLOVIR [WHO-DD], MLS001077349, BIDD:GT0783, SPBio_002718, GANCICLOVIR [EMA EPAR], BPBio1_000877, orb1310384, Ganciclovir - Bio-X trade mark, SCHEMBL14491348, BDBM85707, GANCICLOVIR [EP IMPURITY], GANCICLOVIR [ORANGE BOOK], IRSCQMHQWWYFCW-UHFFFAOYSA-N, 2-[(2-amino-6-hydroxypurin-9-yl)methoxy]propane-1,3-diol, GANCICLOVIR [EP MONOGRAPH], GLXC-07993, HMS1570H19, HMS2090K08, HMS2097H19, HMS2235C21, HMS3259B13, HMS3261L19, HMS3371H01, HMS3604L19, HMS3655M18, HMS3714H19, HMS5080O17, Pharmakon1600-01502362, GANCICLOVIR [USP MONOGRAPH], G72257IO, MSK10028, NSC_3454, Tox21_110160, Tox21_500539, 2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol, BBL029078, BDBM50237614, EBC-07889, EBC-13406, HY-13637R, NSC759656, PDSP1_000816, PDSP2_000803, SBB066292, STK801910, STL514515, AKOS004119898, AKOS026749928, AKOS037492029, Tox21_110160_1, Valganciclovir hydrochloride impurity a, AC-8069, CCG-204629, CS-2014, DB01004, FG16550, Ganciclovir, >=99% (HPLC), powder, KS-1065, LP00539, NC00647, NSC 759656, SDCCGSBI-0050522.P002, SMP2_000038, NCGC00015471-01, NCGC00015471-03, NCGC00015471-04, NCGC00015471-05, NCGC00015471-06, NCGC00015471-08, NCGC00015471-16, NCGC00093928-01, NCGC00093928-02, NCGC00168567-01, NCGC00188980-01, NCGC00261224-01, 9-(1,3-dihydroxy-2propoxymethyl)guanine, BG164496, HY-13637, SY027981, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, CAS_82410-32-0, 9-(1,3-dihydroxy-2-propoxymethyl)-guanine, 9-(1,3-Dihydroxy-2-propoxymethyl)guanine;, EU-0100539, G0315, NS00003516, SW197135-3, T0688, EN300-49857, C07019, D00333, 9-[[(1,3-Dihydroxy-2-propyl)oxy]methyl]guanine, F212141, Ganciclovir, Antibiotic for Culture Media Use Only, Q417640, SR-01000721941, Q-201148, SR-01000075894-1, SR-01000075894-4, SR-01000721941-3, BRD-K22662435-001-17-5, BRD-K22662435-001-18-3, BRD-K22662435-001-19-1, Z594284200, Ganciclovir, European Pharmacopoeia (EP) Reference Standard, VALGANCICLOVIR HYDROCHLORIDE IMPURITY A [USP IMPURITY], Ganciclovir, United States Pharmacopeia (USP) Reference Standard, 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]6H-purin-6-one, 2-amino-9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl}hydropurin-6-one, Ganciclovir, Pharmaceutical Secondary Standard; Certified Reference Material, 2-amino-9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl}-1,9-dihydro-6H-purin-6-one, Ganciclovir, 1.0 mg/mL (1% 1M HCl in Methanol), certified reference material, Guanine, 9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)- and MSL, neutralizing monoclonal antibody
Theoretical properties:
molecular_formula: C9H13N5O4
molecular_weight: 255.23 g/mol
exact_mass: 255.09675391 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 5
heavy_atom_count: 18
topological_polar_surface_area: 135 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Crystals from methanol
color: Crystals from methanol
Descriptions:
pubchem: Ganciclovir can cause cancer, developmental toxicity and male reproductive toxicity according to state or federal government labeling requirements.
chebi: An oxopurine that is  guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
chembl: GANCICLOVIR is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Ganciclovir, sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections.
Ganciclovir was patented in 1980 and approved for medical use in 1988.