Compound: iproniazid
SMILES: O=C(NNC(C)C)c1ccncc1
InChIKey: NYMGNSNKLVNMIA-UHFFFAOYSA-N
Synonyms: iproniazid, 54-92-2, Iprazid, Iproniazide, Euphozid, Rivivol, N'-isopropylpyridine-4-carbohydrazide, 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, Iproniazida, Iproniazidum, Ro 2-4572, 1-Isonicotinoyl-2-isopropylhydrazine, Isonicotinic acid 2-isopropylhydrazide, D892HFI3XA, DTXSID5023168, RefChem:148662, DTXCID503168, 200-218-8, N'-Isopropylisonicotinohydrazide, Marsilid, Marsalid, Yatrozide, MFCD00153819, N'-Isopropylisonicotinoylhydrazide, N'-(propan-2-yl)pyridine-4-carbohydrazide, P 887, CHEMBL92401, ISONICOTINIC ACID, 2-ISOPROPYLHYDRAZIDE, Iproniazid (INN), Iprazide, IPRONIAZID [INN], N'-(1-methylethyl)pyridine-4-carbohydrazide, Iproniazyd [Polish], N inverted exclamation mark -Isopropylisonicotinohydrazide, Iproniazyd, Propilniazida, Ipronid, Iproniazide [INN-French], Iproniazidum [INN-Latin], Iproniazida [INN-Spanish], NSC81850, CCRIS 9177, N-[(methylethyl)amino]-4-pyridylcarboxamide, EINECS 200-218-8, UNII-D892HFI3XA, BRN 0142700, Iproniazid [INN:BAN:DCF], Ipronin, Isonicotinic acid, N'-isopropyl hydrazide, N'-propan-2-ylpyridine-4-carbohydrazide, Spectrum_000268, IPRONIAZID [MI], Prestwick0_000176, Prestwick1_000176, Prestwick2_000176, Prestwick3_000176, Spectrum2_000468, Spectrum3_000272, Spectrum4_000396, Spectrum5_001437, Lopac-I-7627, SCHEMBL4153, IPRONIAZID [WHO-DD], Lopac0_000643, BSPBio_000071, BSPBio_001744, KBioGR_000951, KBioSS_000748, 4-22-00-00551 (Beilstein Handbook Reference), DivK1c_000121, N-Isopropyl isonicotinhydrazide, SPBio_000576, SPBio_001992, BPBio1_000079, CHEBI:5958, Iproniazid - Bio-X trade mark, orb1705831, BDBM29136, HY-B0886A, KBio1_000121, KBio2_000748, KBio2_003316, KBio2_005884, KBio3_001244, N'-isopropylisonicotino hydrazide, NINDS_000121, GLXC-02864, HMS2090F08, HMS3886E05, HMS5083D16, HMS6018G13, N'-Isopropylisonicotinohydrazide #, MSK10884, s4856, SBB003758, AKOS006229272, CCG-204730, DB04818, DS-7371, FI63875, Isonicotinic acid N'-isopropylhydrazide, N'-isopropyl-pyridine-4-carbohydrazide, SDCCGSBI-0050623.P004, IDI1_000121, Isonicotinic acid N'-isopropyl-hydrazide, NCGC00015565-01, NCGC00015565-02, NCGC00015565-03, NCGC00015565-04, NCGC00015565-12, NCGC00162210-01, BI164580, CAS-305-33-9, DA-04957, P887, SY025980, SBI-0050623.P003, AB00053568, CS-0013623, NS00008980, ST50825141, D02579, AB00053568-12, AB00053568_13, AN-068/14539031, F386952, Q421368, BRD-K88568253-011-03-3, BRD-K88568253-011-19-9, BRD-K88568253-065-03-9
Theoretical properties:
molecular_formula: C9H13N3O
molecular_weight: 179.22 g/mol
exact_mass: 179.105862047 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 3
heavy_atom_count: 13
topological_polar_surface_area: 54 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 161-161.5
Descriptions:
pubchem: Iproniazid is a member of pyridines and a carbohydrazide.
chembl: IPRONIAZID is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class. It is a xenobiotic that was originally designed to treat tuberculosis, but was later most prominently used as an antidepressant drug. However, it was withdrawn from the market because of its hepatotoxicity. The medical use of iproniazid was discontinued in most of the world in the 1960s, but remained in use in France until 2015.