Compound: Moxisylyte
SMILES: O=C(Oc1c(cc(OCCN(C)C)c(c1)C(C)C)C)C
InChIKey: VRYMTAVOXVTQEF-UHFFFAOYSA-N
Synonyms: Moxisylyte, Thymoxamine, 54-32-0, Carlytene, Moxisilita, Acetoxythymoxamine, Moxisylytum, PW8QYA7KI0, (2-(4-Acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylamine, 6-Acetoxythymol 2-(dimethylamino)ethyl ether, DTXSID4023339, 4-[2-(dimethylamino)ethoxy]-2-methyl-5-(propan-2-yl)phenyl acetate, Thymoxyalcylamine, moxisilite, Erecnos, 4-(2-(dimethylamino)ethoxy)-2-methyl-5-(propan-2-yl)phenyl acetate, RefChem:159852, DTXCID403339, C04AX10, G04BE06, 200-204-1, Moxilite, Moxisylyt, Arlytene, Sympal, Vasoklin, 4-(2-(Dimethylamino)ethoxy)-5-isopropyl-2-methylphenyl acetate, Timoxamina, Moxisylyte (INN), MOXISYLYTE [INN], Arlytene; Moxilite; Moxisylite; Moxisylyt; Moxisylyte, [4-[2-(dimethylamino)ethoxy]-2-methyl-5-propan-2-ylphenyl] acetate, Moxisylytum [INN-Latin], Moxisilita [INN-Spanish], NCGC00015678-02, CAS-964-52-3, EINECS 200-204-1, UNII-PW8QYA7KI0, Moxisylyte [INN:BAN:DCF], Carlytene (TN), Carvacrol, 5-(2-(dimethylamino)ethoxy)-, acetate (ester), MOXISYLYTE [MI], Prestwick0_000042, Prestwick1_000042, Prestwick2_000042, Prestwick3_000042, Lopac-M-5154, 4-(2-(Dimethylamino)ethoxy)-2-methyl-5-(1-methylethyl)phenol acetate (ester), MOXISYLYTE [WHO-DD], Phenol, 4-(2-(dimethylamino)ethoxy)-2-methyl-5-(1-methylethyl)-, acetate (ester), Lopac0_000767, 4-Dimethylaminoethoxycarvacrol, BSPBio_000163, SCHEMBL456546, SPBio_002084, BPBio1_000181, CHEMBL159226, orb1740353, CHEBI:94754, GTPL12306, Pharmakon1600-01506079, EBC-26424, NSC759308, ((6-Acetoxythymoxy)ethyl)dimethylamine, CCG-204852, DB09205, NSC-759308, SDCCGSBI-0050745.P003, NCGC00015678-01, NCGC00015678-03, NCGC00015678-04, NCGC00015678-05, NCGC00015678-06, NCGC00015678-07, NCGC00015678-08, NCGC00015678-13, NCGC00024362-03, SBI-0050745.P002, NS00009367, 5-(2-(Dimethylamino)ethoxy)carvacrol acetate, D08239, EN300-18567368, Q646045, SR-01000000205-7, BRD-K81144366-003-03-1, BRD-K81144366-003-19-7, CARVACROL, 5-(2-(DIMETHYLAMINO)ETHOXY)-, ACETATE, [2-(4-Acetoxy-2-isopropyl-5-methylprhenoxy)ethyl]dimethylamine, 4-(2-Dimethylaminoethoxy)-2-methyl-5-isopropylphenyl acetate, 4-(2-Dimethylaminoethoxy)-5-isopropyl-2-methylphenyl acetate, 4-[2-(Dimethylamino)ethoxy]-2-methyl-5-(methylethyl)phenyl acetate, 4-{[2-(dimethylamino)ethyl]oxy}-2-methyl-5-(1-methylethyl)phenyl acetate, Phenol, 4-[2-(dimethylamino)ethoxy]-2-methyl-5-(1-methylethyl)-, acetate, acetic acid [4-[2-(dimethylamino)ethoxy]-2-methyl-5-propan-2-ylphenyl] ester
Theoretical properties:
molecular_formula: C16H25NO3
molecular_weight: 279.37 g/mol
exact_mass: 279.18344366 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 7
heavy_atom_count: 20
topological_polar_surface_area: 38.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
boiling_point: 371ºC at 760 mmHg
melting_point: 145ºC
solubility: >47.4 ug/ml
Descriptions:
pubchem: Acetic acid [4-[2-(dimethylamino)ethoxy]-2-methyl-5-propan-2-ylphenyl] ester is a monoterpenoid.
chembl: MOXISYLYTE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. In the United Kingdom, Moxisylyte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Raynaud's syndrome. This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon tablets help by improving blood circulation to the extremities.