Compound: 4-Hydroxy-6-methyl-2-pyrone
SMILES: O=c1oc(cc(c1)O)C
InChIKey: NSYSSMYQPLSPOD-UHFFFAOYSA-N
Synonyms: 4-Hydroxy-6-methyl-2-pyrone, 675-10-5, 4-Hydroxy-6-methyl-2H-pyran-2-one, 4-hydroxy-6-methylpyran-2-one, Triacetic acid lactone, Triacetate lactone, 2H-PYRAN-2-ONE, 4-HYDROXY-6-METHYL-, S1S883S4EE, NSC-34625, DTXSID1060974, CHEBI:16458, RefChem:523908, DTXCID7044895, 211-619-2, 2-Hydroxy-6-methyl-4H-pyran-4-one, 70254-61-4, MFCD00006641, MFCD18820248, 6-Methyl-4-hydroxypyron-(2), CHEMBL54907, 6-Methyl-4-hydroxypyran-2-one, 4-hydroxy-6-methyl-pyran-2-one, 6-methyl-4-oxidanyl-pyran-2-one, 3,5-Dihydroxysorbic acid delta-lactone, 6-methyl-4-hydroxy-2-pyrone, CCRIS 3600, 4-Hydroxy-6-methylpyran-4-one, EINECS 211-619-2, NSC 34625, BRN 0113815, UNII-S1S883S4EE, 2-hydroxy-6-methyl-pyran-4-one, 4H-Pyran-4-one, 2-hydroxy-6-methyl-, Spectrum_001904, SpecPlus_000816, Spectrum2_001978, Spectrum3_001720, Spectrum4_001907, Spectrum5_000594, 4-hydroxy-6-methylpyrone, 6-methyl-4-hydroxypyrone, 4-hydroxy-6-methyl-pyrone, 4-hydroxy-6-methylpyranone, 4-hydroxy-6-methyl pyranone, BSPBio_003340, KBioGR_002500, KBioSS_002438, 4-hydoxy-6-methyl-2-pyrone, DivK1c_006912, SCHEMBL320025, SCHEMBL918518, SPECTRUM1600759, SPBio_002135, 4- hydoxy-6-methyl-2-pyrone, orb3029312, SCHEMBL6415526, 4-hydroxy- 6-methyl-2-pyrone, 4-hydroxy-6 -methyl-2-pyrone, 4-hydroxy-6-methyl pyr-2-one, SCHEMBL28274573, KBio1_001856, KBio2_002432, KBio2_005000, KBio2_007568, KBio3_002560, 6-methyl-4-hydroxy pyran-2-one, PDK0331, Hydroxy-6-methyl-2-pyrone, 4-, OOKCZXGEYPSNIM-UHFFFAOYSA-N, 3,5-Dihydroxysorbic acid d-lactone, ALBB-021321, HY-Y1634, NSC34625, 3,5-Dihydroxysorbic acid #-lactone, BBL008420, BDBM50405204, CCG-39516, EBC-47560, SBB001910, STK772128, 4-Hydroxy-6-methyl-2-pyrone, 98%, AKOS000119605, AKOS016007260, CS-W020045, SDCCGMLS-0066925.P001, NCGC00095976-01, NCGC00095976-02, NCGC00178130-01, AC-27196, DA-17115, FH129488, FH141377, PD000450, SY001948, SY105730, 4-HYDROXY-6-METHYL-.ALPHA.-PYRONE, DB-055039, ST4083834, CS-0061284, H0715, NS00015328, EN300-20217, 7H-939, C02752, F14831, O10801, F003638, SR-05000002374, Q7839869, SR-05000002374-1, BRD-K77202630-001-02-9, BRD-K77202630-001-03-7, SORBIC ACID, 3,5-DIHYDROXY-, .DELTA.-LACTONE, F0001-1779, Z104477314, InChI=1/C6H6O3/c1-4-2-5(7)3-6(8)9-4/h2-3,7H,1H, KJ6
Theoretical properties:
molecular_formula: C6H6O3
molecular_weight: 126.11 g/mol
exact_mass: 126.031694049 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 0
heavy_atom_count: 9
topological_polar_surface_area: 46.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Triacetate lactone is a member of 2-pyranones. It is a conjugate acid of a triacetate lactone oxoanion.
chembl: 4-HYDROXY-6-METHYLPYRAN-2-ONE is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: The enzyme 4-hydroxy-4-methyl-2-oxoglutarate aldolase (EC 4.1.3.17) catalyzes the chemical reaction

4-hydroxy-4-methyl-2-oxoglutarate 
  
    
      
        ⇌
      
    
    {\displaystyle \rightleftharpoons }
  
 2 pyruvate
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds.  The systematic name of this enzyme class is 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming). Other names in common use include pyruvate aldolase, gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase, 4-hydroxy-4-methyl-2-ketoglutarate aldolase, and 4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase.  This enzyme participates in benzoate degradation via hydroxylation and c5-branched dibasic acid metabolism.