Compound: picotamide
SMILES: O=C(NCc1cnccc1)c2c(OC)ccc(c2)C(=O)NCc3cnccc3
InChIKey: KYWCWBXGRWWINE-UHFFFAOYSA-N
Synonyms: picotamide, 32828-81-2, 4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide, 4-methoxy-1-N,3-N-bis(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide, G-137, NSC-304384, 654G2VCI4Q, DTXSID40186498, RefChem:174171, DTXCID50108989, 4-methoxy-N1,N3-bis((pyridin-3-yl)methyl)benzene-1,3-dicarboxamide, 251-245-7, 4-methoxy-N1,N3-bis(pyridin-3-ylmethyl)isophthalamide, EINECS 251-245-7, Picotamide [INN:BAN], BRN 0499268, UNII-654G2VCI4Q, SR-01000076086, G 137, N,N'-Bis(3-picolyl)-4-methoxyisophthalamide, 4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthalamide, Picotamide (BAN), 4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide, Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-, PICOTAMIDE [MI], N,N'-Bis(3-pyridinylmethyl)-4-methoxy-1,3-benzenedicarboxamide, 1085306-93-9, Prestwick0_000119, Prestwick1_000119, Prestwick2_000119, Prestwick3_000119, Lopac-P-8477, PICOTAMIDE [MART.], PICOTAMIDE [WHO-DD], Lopac0_001003, BSPBio_000138, N,N'-Bis(3-pyridylmethyl)-4-methoxyisophthalamide, SCHEMBL137025, SPBio_002077, BPBio1_000152, orb1298325, CHEMBL1257015, SCHEMBL30206880, SCHEMBL30254057, CHEBI:93175, GTPL11379, KYWCWBXGRWWINE-UHFFFAOYSA-N, HMS2090L18, HMS3263I07, HY-B1735, Tox21_501003, 1,3-Benzenedicarboxamide, N,N'-bis(3-pyridinylmethyl)-4-methoxy-, BDBM50103507, MFCD00866792, NSC304384, AKOS040759696, CCG-205083, DB13327, LP01003, NSC 304384, SDCCGSBI-0050976.P003, NCGC00015847-01, NCGC00015847-02, NCGC00015847-03, NCGC00015847-04, NCGC00015847-05, NCGC00094297-01, NCGC00094297-02, NCGC00261688-01, FP146861, MS-26107, SBI-0050976.P002, DB-048275, EU-0101003, NS00029358, D07140, G63334, P 8477, L013375, Q1235921, SR-01000076086-1, BRD-K67277431-002-03-0, BRD-K67277431-002-10-5, 4-methoxy-N1,N3-bis(3-pyridylmethyl)benzene-1,3-dicarboxamide, 1,3-Benzenedicarboxamide, 4-methoxy-N,N'-bis(3-pyridinylmethyl)-, 4-methoxy-N1,N3-bis(3-pyridinylmethyl)benzene-1,3-dicarboxamide, 1,3-BENZENEDICARBOXAMIDE, 4-METHOXY-N1,N3-BIS(3-PYRIDINYLMETHYL)-, 4-Methoxy-N~1~,N~3~-bis[(pyridin-3-yl)methyl]benzene-1,3-dicarboxamide, Picotamide; 1,3-Benzenedicarboxamide, 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-; 1,3-Benzenedicarboxamide, 4-methoxy-N,N'-bis(3-pyridinylmethyl)- (9CI); Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)- (8CI); 4-Methoxy-N1,N3-bis(3-pyridinylmethyl)-1,3-benzenedicarb
Theoretical properties:
molecular_formula: C21H20N4O3
molecular_weight: 376.4 g/mol
exact_mass: 376.15354051 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 7
heavy_atom_count: 28
topological_polar_surface_area: 93.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 4-methoxy-N1,N3-bis(3-pyridinylmethyl)benzene-1,3-dicarboxamide is a member of benzamides.
chembl: PICOTAMIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase -1.0.
wikipedia: Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor. Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.