Compound: 7,12-Dimethylbenz[a]anthracene
SMILES: c12c3c(ccc1c(c4ccccc4c2C)C)cccc3
InChIKey: ARSRBNBHOADGJU-UHFFFAOYSA-N
Synonyms: 7,12-Dimethylbenz[a]anthracene, 57-97-6, DMBA, 7,12-dimethyltetraphene, 7,12-Dimethylbenzanthracene, 7,12-DIMETHYLBENZ(A)ANTHRACENE, 9,10-Dimethyl-1,2-benzanthracene, 7,12-DMBA, 7,12-Dimethylbenzo[a]anthracene, 1,4-Dimethyl-2,3-benzphenanthrene, 6,7-Dimethyl-1,2-benzanthracene, 7,12-Dimethyl-1,2-benzanthracene, 7,12-Dimethylbenzanthrancene, 9,10-Dimethyl-1,2-benzanthrazen, 7,12-Dimethyl-1:2-benz(a)anthracene, Benz(a)anthracene, 7,12-dimethyl-, NCI-C03918, Benz[a]anthracene, 7,12-dimethyl-, DTXSID1020510, 7,12-Dimethylbenzo(a)anthracene, 7,12 Dimethylbenzanthracene, Dimethylbenzanthracene, AI3-50460, CHEBI:254496, F05B6S0395, NSC-408823, DTXCID70510, NSC408823, RefChem:914122, 200-359-5, 9,10-Dimethylbenz(a)anthracene, MFCD00003600, NSC 408823, 9,10-Dimethylbenz[a]anthracene, RCRA waste number U094, CAS-57-97-6, SMR000857253, CCRIS 274, HSDB 2938, EINECS 200-359-5, RCRA waste no. U094, BRN 1912135, 9,10-Dimethyl-1,2-benzanthrazen [German], UNII-F05B6S0395, Dimethylbenzanthrene, 9,2-benzanthrazen, 6,2-benzanthracene, 7,2-benzanthracene, 9,2-benzanthracene, DMBZA, 1,3-benzphenanthrene, Epitope ID:119712, SCHEMBL99213, 4-05-00-02587 (Beilstein Handbook Reference), MLS001333155, MLS001333156, MLS002454381, CHEMBL329673, orb1693526, Benz[a]anthracene,10-dimethyl-, SCHEMBL29382459, SCHEMBL29403351, SCHEMBL29531544, 7,12-Dimethylbenz(a)ant racene, 712-Dimethyl-benzo[a]anthracene, 7,12-dimethylbenzo[b]phenanthrene, HMS2232O09, 7,12-dimethyl-benzo[b]phenanthrene, Tox21_201805, Tox21_300500, MSK001486, AKOS015903190, CS-W012561, FD22356, HY-W011845, MSK001486-100M, WLN: L D6 B666J C1 J1, WLN: L D6 B666J F1 G1, MSK001486-1000M, NCGC00091518-01, NCGC00091518-02, NCGC00091518-03, NCGC00091518-04, NCGC00091518-05, NCGC00091518-06, NCGC00091518-07, NCGC00254337-01, NCGC00259354-01, BS-43984, SY048772, 7,12-Dimethylbenz[a]anthracene, >=95%, 7,12-Dimethylbenz[a]anthracene, >=98%, DB-053137, D0677, NS00008928, ST45022242, C19488, T71090, 9,10-DIMETHYL-1,2-BENZANTHRACENE [MI], F827799, Q187487, 7,12-Dimethylbenz[a]anthracene, analytical standard, 7,12-Dimethylbenz[a]anthracene Solution in Methanol, 100ug/mL, 7,12-Dimethylbenz[a]anthracene Solution in Methanol, 1000ug/mL
Theoretical properties:
molecular_formula: C20H16
molecular_weight: 256.3 g/mol
exact_mass: 256.125200510 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 0
rotatable_bond_count: 0
heavy_atom_count: 20
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Plates, leaflets from acetone-alcohol, faint greenish-yellow tinge
color: Plates, leaflets from acetone-alcohol, faint greenish-yellow tinge
odor: Odorless[NOAA; CAMEO Chemicals. Database of Hazardous Materials. 7,12-Dimethylbenz
melting_point: 252 to 253 °F (NTP, 1992)
solubility: less than 1 mg/mL at 64 °F (NTP, 1992)
flash_point: 187 °F (NTP, 1992)
vapor_pressure: 0.0000002 [mmHg]
Descriptions:
pubchem: 7,12-Dimethylbenz(a)anthracene can cause cancer according to The Environmental Protection Agency (EPA).
chebi: A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: 7,12-Dimethylbenz[a]anthracene (DMBA) is an immunosuppressor and a powerful organ-specific laboratory carcinogen. DMBA is widely used in many research laboratories studying cancer. DMBA serves as a tumor initiator. Tumor promotion can be induced with treatments of 12-O-tetradecanoylphorbol-13-acetate (TPA) in some models of two-stage carcinogenesis. This allows for a greatly accelerated rate of tumor growth, making many cancer studies possible.