Compound: Sesamol
SMILES: O1c2c(ccc(c2)O)OC1
InChIKey: LUSZGTFNYDARNI-UHFFFAOYSA-N
Synonyms: Sesamol, 533-31-3, 1,3-Benzodioxol-5-ol, 3,4-Methylenedioxyphenol, 5-Hydroxy-1,3-benzodioxole, 2H-1,3-Benzodioxol-5-Ol, Methylene ether of oxyhydroquinone, Phenol, 3,4-(methylenedioxy)-, DTXSID9021267, 94IEA0NV89, NSC-59256, DTXCID101267, RefChem:25934, 208-561-5, 3,4-(Methylenedioxy)phenol, 3,4-Methylendioxyphenol, benzo[d][1,3]dioxol-5-ol, MFCD00005827, 5-Benzodioxolol, 1,3-Benzodioxol-5-ol (Sesamol), 2H-benzo[d]1,3-dioxolen-5-ol, sesamol lithium, sesamol sodium, CCRIS 1386, sesamol, ion (1+), sesamol titanium (+4), EINECS 208-561-5, NSC 59256, BRN 0127405, UNII-94IEA0NV89, AI3-17298, benzodioxol-5-ol, BZX, 1,2,4-Benzenetriol methylene ether, Sesamol (Standard), ORISTAR MDP, Sesamol, 98%, 3ao1, 1,3-dioxaindan-5-ol, 4,5-methylenedioxyphenol, 3,4-methylendioxy-phenol, benzo[1,3]dioxol-5-ol, 3,4-methylenedioxy phenol, 3,4-methylenedioxy-phenol, 1, 3-Benzodioxol-5-ol, 3,4 Methylenedioxy Phenol, (3,4-methylenedioxy)phenol, Sesamol, analytical standard, Phenol,4-(methylenedioxy)-, SCHEMBL20959, 5-Hydroxybenzo[1,3]dioxole, 5-19-02-00532 (Beilstein Handbook Reference), 3,4-(Methylenedioxy)-Phenol, SCHEMBL921252, 5-hydroxy-1,3-benzodioxolane, 5-hydroxy-benzo[1.3]dioxole, 5-Hydroxy-1, 3-benzodioxole, 5-hydroxylbenzo[1,3]dioxolane, CHEBI:9126, orb1303917, orb3140949, SCHEMBL5872221, 1,3-Benzodioxol-5-ol, 9CI, CHEMBL1517998, SCHEMBL29510426, BDBM36291, HSDB 8495, HY-N1417R, MSK5403, WLN: T56 BO DO CHJ GQ, HY-N1417, NSC59256, YLB93205, 4-hydroxy-1,2-methylenedioxybenzene, Tox21_201211, 3,4-(Methylenedioxy)phenol; 1,3-Benzodioxol-5-ol; 5-Benzodioxolol, BBL027539, EBC-44282, s3626, SBB085996, STK568334, Sesamol, purum, >=98.0% (GC), AKOS005493905, CCG-266144, FS38157, GF-0128, SDCCGMLS-0066221.P001, Paroxetine HCl Anhydrous EP Impurity B, NCGC00091628-01, NCGC00091628-02, NCGC00258763-01, AC-11668, AC-35089, CAS-533-31-3, Sesamol, Vetec(TM) reagent grade, 98%, SY015819, DB-021955, CS-0016841, NS00013864, S0418, ST50330663, EN300-19382, F358234, Q418080, SR-01000944738, SR-01000944738-1, F0001-1376, Z104473678, InChI=1/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H, Paroxetine Hydrochloride Anhydrous EP Impurity B; Paroxetine Hydrochloride EP Impurity B
Theoretical properties:
molecular_formula: C7H6O3
molecular_weight: 138.12 g/mol
exact_mass: 138.031694049 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 0
heavy_atom_count: 10
topological_polar_surface_area: 38.7 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Crystals from chloroform/petroleum ether
color: Crystals from chloroform/petroleum ether
boiling_point: 272.00 to 274.00 °C. @ 760.00 mm Hg
melting_point: 64.9 °C
solubility: slightly
Descriptions:
pubchem: Sesamol is a member of benzodioxoles.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Sesamol is a natural organic compound which is a component of sesame seeds and sesame oil, with anti-inflammatory, antioxidant, antidepressant and neuroprotective properties. It is a white crystalline solid that is a derivative of phenol.  It is sparingly soluble in water, but miscible with most oils. It can be produced by organic synthesis from heliotropine.
Sesamol has been found to be an antioxidant that may prevent the spoilage of oils.  It also may prevent the spoilage of oils by acting as an antifungal. It can be used in the synthesis of paroxetine.
Sesamol's molecular targets and mechanism of action, at least for its antidepressant-like effects, is found to be through the brain nerve growth factor (NGF) and endocannabinoid signalling under the regulatory drive of the CB1 receptors. 
Alexander Shulgin used sesamol in his book PiHKAL to make MMDA-2.