Compound: (S)-Azetidine-2-carboxylic acid
SMILES: O=C(O)[C@H]1NCC1
InChIKey: IADUEWIQBXOCDZ-VKHMYHEASA-N
Synonyms: (S)-Azetidine-2-carboxylic acid, (2S)-azetidine-2-carboxylic acid, (S)-2-Azetidinecarboxylic acid, 2-Azetidinecarboxylic acid, (S)-, 2-Azetidinecarboxylic acid, (2S)-, (S)-(-)-2-azetidine carboxylic acid, CHEBI:6198, RefChem:25831, 218-362-5, 2133-34-8, L-Azetidine-2-carboxylic acid, (S)-(-)-2-Azetidinecarboxylic acid, Azetidyl-2-carboxylic acid, L-Azetidine 2-carboxylic acid, (S)-(-)-Azetidine-2-carboxylic acid, (L)-AZETIDINE-2-CARBOXYLIC ACID, Azetidine-2-carboxylic acid, L-, MFCD00005166, 2-Azetidinecarboxylic acid, L-, 5GZ3E0L9ZU, L-2-Azetidinecarboxylic acid, Acide L-azetidine-2-carboxylic, CHEMBL1165239, L-azetidine-2-carboxylate, (2S)azetidine-2-carboxylic acid, ST059592, (2s)-2-azetidinecarboxylic acid, azetidine-2-carboxylate, (S)-Azetidine-2-carboxylicacid, HSDB 3465, AzeOH, 02A, (S)-2-Azetidinecarboxylic acid;H-Aze-OH, EINECS 218-362-5, L-AzeOH, L-Trimethyleneimine-2-carboxylic Acid, (S)-(-) Azetidine-2-carboxylic acid, Acide L-azetidine-2-carboxylic [French], H-Aze(2)-OH, UNII-5GZ3E0L9ZU, L-azetidine-2caboxylic acid, (S)-Azetidin-2-carbonsaure, L-azetidine-2carboxylic acid, Lopac0_000023, SCHEMBL20296, (S)-2-azetidinecarboxyic acid, GTPL4686, orb1296944, SCHEMBL2223619, 2-(S)-azetidinecarboxylic acid, azetidine-2(S)-carboxylic acid, L--Azetidine-2-carboxylic acid, DTXSID0044020, L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline], (S)-2-azetidine carboxylic acid, azetidine-2-(S)-carboxylic acid, HMS3260E07, (S)-L-Azetidine-2-carboxylic acid, Tox21_500023, (-)-AZETIDINECARBOXYLIC ACID, BDBM50357225, SBB004365, AKOS005254687, AKOS006239010, (S)-(-)-2-azetidine-carboxylic acid, AC-5699, CCG-204119, EBC-253170, FA14215, HY-W050044, LP00023, SDCCGSBI-0050012.P002, L-Azetidine-2-carboxylic acid, >=99%, NCGC00093546-01, NCGC00093546-02, NCGC00093546-03, NCGC00093546-04, NCGC00260708-01, DS-16309, SY004809, AZETIDYL-2-CARBOXYLIC ACID [HSDB], A1043, CS-0031389, EU-0100023, NS00048671, EN300-85821, A 0760, C08267, AN-584/43509810, F040006, Q793715, SR-01000075656, SR-01000075656-1, L-Azetidine-2-carboxylic acid is known as a proline analog.
Theoretical properties:
molecular_formula: C4H7NO2
molecular_weight: 101.10 g/mol
exact_mass: 101.047678466 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 1
heavy_atom_count: 7
topological_polar_surface_area: 49.3 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: CRYSTALS FROM 95% HOT METHANOL
color: CRYSTALS FROM 95% HOT METHANOL
solubility: SOL IN COLD & HOT WATER; PRACTICALLY INSOL IN ABSOLUTE ETHANOL
Descriptions:
pubchem: (S)-azetidine-2-carboxylic acid is the (S)-enantiomer of azetidine-2-carboxylic acid. It is an enantiomer of a (R)-azetidine-2-carboxylic acid. It is a tautomer of a (S)-azetidine-2-carboxylate zwitterion.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Azetidine-2-carboxylic acid (abbreviated Aze or Azc) is a plant non-protein amino acid homologue of proline with the molecular formula C4H7NO2. Aze is a heterocyclic, 4 membered ring with nitrogen as its heteroatom (an azetidine), and a carboxylic acid group substituted on one of the ring carbon atoms.  The main difference between Aze and proline is the ring of Aze has four members and the ring of proline has five. Aze has the ability to act as an analog of proline and can be incorporated into proteins in place of proline.