Compound: hydroquinone
SMILES: Oc1ccc(O)cc1
InChIKey: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
Synonyms: hydroquinone, 123-31-9, Benzene-1,4-diol, 1,4-benzenediol, Quinol, 1,4-Dihydroxybenzene, p-Hydroquinone, p-Hydroxyphenol, p-Benzenediol, p-Dihydroxybenzene, 4-Hydroxyphenol, hydroquinol, Benzoquinol, Eldopaque, Eldoquin, Hydroquinole, Phiaquin, Tecquinol, p-Dioxybenzene, Solaquin forte, Idrochinone, Benzohydroquinone, Hidroquinone, Arctuvin, Tequinol, Dihydroxybenzene, Tenox HQ, Eldopaque Forte, Eldoquin Forte, Hydrochinon, Usaf ek-356, Diak 5, Benzene, p-dihydroxy-, 1,4-Dihydroxy-benzol, 1,4-Diidrobenzene, p-Dioxobenzene, 1,4-Dihydroxybenzen, para-Dioxybenzene, para-Hydroquinone, NCI-C55834, Pyrogentistic acid, Black and White Bleaching Cream, 1,4-Dihydroxy-benzeen, para-Dihydroxybenzene, beta-quinol, alpha-hydroquinone, DTXSID7020716, CHEBI:17594, NSC-9247, XV74C1N1AE, Hydroquinone (USP), Hydroquinone [USP], DTXCID70716, NSC9247, Balancer, Medisilke, Supermax, Medisilke Night, Skin Lightener, Skin Lightening, Topiclear Paris, Clear Action, Double White, Exence White, Hydroquinone gel, Idole Carrot, Miracle Fade, Movate Carrot, Movate Lemon, Scarlight Md, Caro Light, Hot Movate, Idole Black, Topiclear Carrot, Body Fade Creme, Hydroquinone 4%, Ultra Glow Fade, Hydroquinone cream, Light The Way, Vivant True Tone, Hydro-Q, Obagi-C, Brighten Lightening, I-max Lightening L, I-max Lightening 5, PIONA, Skin lightening Cream, African Formula Black, Idole Skin Lightening, Skin Beautifying Milk, African Formula Carrot, Essential Fade Complex, Neova Complex Hq Plus, NU-DERM BLENDER, NU-DERM CLEAR, RefChem:5893, Skin Lightening Complex, SYMBA Skin Lightening, Image Md Lightening Rx, Vivant True Tone Forte, HYDROQUINONE 6%, HYDROQUINONE 8%, Gold Cosmetics Adi Clear, Rejuvaderm Medispa Fading, Topiclear Skin Lightening, Dermaclair Skin Lightening, HYDROQUINONE 8%., HQ Plus Brightening Cream, Advanced Dual Complex Fade, Dark Spot Lightening Cream, PLUS Skin lightening Cream, Gold Cosmetics Bleach Cream, Vividly Brilliant Perfecting, Skin Lightening Rodan Fields, Pure Valley Miracle Age Spot, Precious Beauty Skin Lightening, ULTIMATE Skin lightening Cream, Body Fade Creme Maximum Strength, Gold Cosmetics Bleach Cream Forte, CONDITION AND ENHANCE CLEAR, OLIVIA QUIDO BLEMISH ERASER, Ageless Total Skin Bleaching Serum, Gold Cosmetics Bleach Cream Silver, Divine Derrier Skin Bleaching cream, HQ Plus Brightening Cream VI Derm, Obagi-C Rx system C-Therapy Night, CONDITION AND ENHANCE BLENDER, Dermisa Skin Fade Vitamin C infused, 141010 HYDROQUINONE 4%, 141011 HYDROQUINONE 6%, 141030 HYDROQUINONE 8%, 141055 HYDROQUINONE 6%, 141067 HYDROQUINONE 8%, Idole Natural Organic Skin Lightening, Obagi C Rx System C Clarifying Serum, Teatrical Pro-Aclarant Skin Lightening, Hydroquinone, Octisalate and Zinc Oxide, Dr. Throwers Skin Lightening Moisturizing, Nu-derm Blender Skin Lightener and Blending, Nu-derm Clear Skin Bleaching and Corrector, Advanced Dual Complex Fade Maximum Strength Plus, ZO Skin Health Pigment Control Creme Hydroquinone, ELASTIDERM DECOLLETAGE SKIN LIGHTENING COMPLEX, Condition and Enhance Clear Skin Bleaching and Corrector, OBAGI-C Rx system C-CLARIFYING SERUM NORMAL TO oily, ZO Skin Health Pigment Control Program Plus Hydroquinone, Condition and Enhance Blender Skin Lightener and Blending, HYDROQUINONE, HOMOSALATE, OCTISALATE AND ZINC OXIDE, HYDROQUINONE, HOMOSALATE, OCTISALATE, and ZINC OXIDE, Elastiderm Decolletage Skin Lightening Complex Chest and Neck, ZO Skin Health Pigment Control Plus Blending Creme Hydroquinone, Obagi-C Rx system C-Therapy Night Skin Lightening with Vitamins C and E, ZO Skin Health Pigment Control plus Brightening Creme Hydroquinone plus Vitamin C, 204-617-8, OBAGI-C Rx system C-CLARIFYING SERUM NORMAL TO oily SKIN LIGHTENING SERUM WITH VITAMIN C, Dihydroquinone, Artra, Derma-Blanch, Hydrochinone, HE 5, Melanex, Idrochinone [Italian], Hydrochinon [Czech, Polish], 1,4-Dihydroxybenzen [Czech], 1,4-Diidrobenzene [Italian], 1,4-Dihydroxy-benzeen [Dutch], 1,4-Dihydroxy-benzol [German], NSC 9247, p-dihydroxy benzene, UN2662, AI3-00072, MFCD00002339, HQ, CHEMBL537, Hydroquinone [UN2662]  [Poison], NCGC00015523-02, para-Hydroxyphenol, Quinol; 1,4-Benzenediol; 1,4-Dihydroxybenzene, Benzene-1,4-diol (Hydroquinone), Eldopacque, Epiquin, Sunvanish, p Benzendiol, p-Dihydroquinone, CAS-123-31-9, SMR000059154, CCRIS 714, 1,4-Hydroxybenzene, Black & White Bleaching Cream, HSDB 577, SR-01000075920, 4-DIHYDROXYBENZENE, EINECS 204-617-8, UNII-XV74C1N1AE, hydroquinon, Hydroquinoue, hydroq uinone, hydroquinone gr, a-Hydroquinone, p-Hydroxybenzene, b-Quinol, 4-Benzenediol, 4-hydroxy-phenol, Hydroquinone, HQ, .beta.-Quinol, 1,4 benzenediol, PLQ, Artra (Salt/Mix), HYDROP, .alpha.-Hydroquinone, phenol derivative, 4, 4-hydroxyphenyl alcohol, Spectrum_001757, 4e3h, SpecPlus_000769, 1,4-Dihydrobenzoquinone, ELDOQUIN (TN), hydroquinone for synthesis, Spectrum2_001672, Spectrum3_000656, Spectrum4_000633, Spectrum5_001430, HYDROQUINONE [MI], Lopac-H-9003, WLN: QR DQ, bmse000293, Epitope ID:116206, EC 204-617-8, HYDROQUINONE [HSDB], HYDROQUINONE [IARC], HYDROQUINONE [VANDF], 1,4-Dihydroxybenzene Quinol, Lopac0_000577, SCHEMBL15516, SCHEMBL50071, BSPBio_002291, HYDROQUINONE [MART.], KBioGR_001246, KBioSS_002237, 1,4-Dihydroxybenzene, XIII, MLS000069815, MLS001074911, orb342175, BIDD:ER0340, DivK1c_006865, HYDROQUINONE [USP-RS], HYDROQUINONE [WHO-DD], Hydroquinone, LR, >=99%, SCHEMBL396267, SCHEMBL739813, SCHEMBL835344, SPECTRUM1504237, Hydrochinon(CZECH, POLISH), SPBio_001883, SCHEMBL2991028, SCHEMBL10782451, BDBM26190, Hydroquinone, puriss., 99.0%, KBio1_001809, KBio2_002237, KBio2_004805, KBio2_007373, KBio3_001511, MSK2901, HMS1922H15, HMS2093E08, HMS3261D16, HYDROQUINONE [ORANGE BOOK], Pharmakon1600-01504237, HY-B0951, HYDROQUINONE [USP MONOGRAPH], Tox21_110169, Tox21_202345, Tox21_300015, Tox21_500577, CCG-39082, EBC-00526, MSK2901-100M, NSC758707, s4580, SBB060421, STK397446, AKOS000119003, MSK2901-1000M, Tox21_110169_1, TRI-LUMA COMPONENT HYDROQUINONE, DB09526, Etamsylate EP Impurity A; Hydroquinone, FH01233, LP00577, NSC-758707, RP10102, SDCCGSBI-0050559.P003, UN 2662, Hydroquinone, ReagentPlus(R), >=99%, Hydroquinone, USP, 99.0-100.5%, NCGC00015523-01, NCGC00015523-03, NCGC00015523-04, NCGC00015523-05, NCGC00015523-06, NCGC00015523-07, NCGC00015523-08, NCGC00015523-09, NCGC00015523-10, NCGC00015523-11, NCGC00015523-12, NCGC00015523-13, NCGC00015523-19, NCGC00090880-01, NCGC00090880-02, NCGC00090880-03, NCGC00090880-04, NCGC00090880-05, NCGC00254037-01, NCGC00259894-01, NCGC00261262-01, BP-21160, DA-33570, Hydroquinone, ReagentPlus(R), >=99.5%, SBI-0050559.P002, Hydroquinone, SAJ first grade, >=99.0%, EU-0100577, H0186, Hydroquinone Solution in Methanol, 100ug/mL, Hydroquinone, SAJ special grade, >=99.0%, NS00004421, ST50214344, EN300-18053, Hydroquinone Solution in Methanol, 1000ug/mL, Hydroquinone, meets USP testing specifications, benzene-1,4-diol (hydroquinone); Hydroquinone, C00530, D00073, H 9003, AB00053361_08, F146000, Q419164, BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY], SR-01000075920-1, SR-01000075920-4, BRD-K11227669-001-07-8, BRD-K11227669-001-08-6, Q27102742, Z57127551, 094CADDB-59BF-4EDF-B278-59791B203EA2, F1908-0167, Hydroquinone, certified reference material, TraceCERT(R), Hydroquinone, United States Pharmacopeia (USP) Reference Standard, InChI=1/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8, Hydroquinone, Pharmaceutical Secondary Standard; Certified Reference Material
Theoretical properties:
molecular_formula: C6H6O2
molecular_weight: 110.11 g/mol
exact_mass: 110.036779430 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 0
heavy_atom_count: 8
topological_polar_surface_area: 40.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: White crystals
color: White crystals
odor: Odorless
boiling_point: 545 to 549 °F at 760 mmHg (EPA, 1998)
melting_point: 338 to 340 °F (EPA, 1998)
density: 1.332 at 59 °F (EPA, 1998) - Denser than water; will sink
solubility: 10 to 50 mg/mL at 68 °F (NTP, 1992)
flash_point: 329 °F (EPA, 1998)
vapor_pressure: 4 mmHg at 302 °F (EPA, 1998)
Descriptions:
pubchem: Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other. It has a role as an antioxidant, a cofactor, a carcinogenic agent, a mouse metabolite, a human xenobiotic metabolite, an Escherichia coli metabolite and a skin lightening agent. It is a benzenediol and a member of hydroquinones.
chebi: A benzenediol comprising benzene core carrying two hydroxy substituents <em>para</em> to each other.
chembl: HYDROQUINONE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones. The name "hydroquinone" was coined by Friedrich Wöhler in 1843.
In 2023, it was the 274th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.