Compound: Methylephedrine
SMILES: O[C@H](c1ccccc1)[C@@H](N(C)C)C
InChIKey: FMCGSUUBYTWNDP-ONGXEEELSA-N
Synonyms: Methylephedrine, 552-79-4, (1R,2S)-2-Dimethylamino-1-phenyl-1-propanol, 60VH42A1KJ, NSC-760389, Benzenemethanol, alpha-((1S)-1-(dimethylamino)ethyl)-, (alphaR)-, (1R)-2-(dimethylamino)-1-phenylpropan-1-ol, RefChem:1089689, 209-022-7, 2-(dimethylamino)-1-phenylpropan-1-ol, (1R,2S)-2-(dimethylamino)-1-phenylpropan-1-ol, (-)-N-Methylephedrine, dl-methylephedrine, (-)-methylephedrine, Methylephedrine, (+/-)-, Methylephedrine, DL-, SHS9PGQ2LS, (+/-)-Methylephedrine, (+/-)-n-methylephedrine, DTXSID7045992, (1r,2s)-n-methylephedrine, N-METHYL (-)EPHEDRINE, Tybraine, (1R,2S)-2-(dimethylamino)-1-phenyl-1-propanol, L-Methylephedrine, Methylephedrine ((1R,2S)-Methylephedrine), (1Rs,2Rs)-2-dimethylamino-1-phenylpropan-1-ol, EINECS 209-022-7, Methylephedrine [INN:BAN], UNII-60VH42A1KJ, L-erythro-2-Dimethylamino-1-phenylpropanol, NCGC00095782-01, 1201-56-5, L-erythro-alpha-(1-Dimethylaminoethyl)benzylalkohol, Methylephedrine (BAN), Spectrum_000431, UNII-SHS9PGQ2LS, Spectrum2_001196, Spectrum3_000671, Spectrum4_000739, Spectrum5_001055, N-methylephedrine DL-form, SCHEMBL99673, BSPBio_002361, KBioGR_001038, KBioSS_000911, N-METHYL(-)EPHEDRINE, DivK1c_000283, SPECTRUM2300220, SPBio_001271, N-METHYLEPHEDRINE [MI], CHEMBL445001, DTXCID5025992, METHYLEPHEDRINE [WHO-DD], (1r,2s)-(-)n-methylephedrine, HMS500O05, KBio1_000283, KBio2_000911, KBio2_003479, KBio2_006047, KBio3_001581, CHEBI:113556, NINDS_000283, HMS3264G05, Pharmakon1600-02300220, N-methyl-(-)ephedrine-[1R,2S], EINECS 214-859-6, Tox21_111521, CCG-39547, MFCD00004504, N-Methylephedrine; LC-tDDA; CE40, NSC760389, AKOS006281830, DB11278, N-METHYLEPHEDRINE DL-FORM [MI], NSC 760389, IDI1_000283, NCGC00178692-01, NCGC00178692-02, NCGC00178692-04, NCGC00181086-01, AC-15988, CAS-552-79-4, (1R,2S)-(-)-N-Methylephedrine, 99%, NS00002861, D08206, AB00052416_02, (1R,2S)-2-(dimethylamino)-1-phenyl-propan-1-ol, Q2331543, BRD-K82236108-001-02-3, BRD-K82236108-001-03-1, BRD-K82236108-001-04-9, (R*,S*)-(1)-alpha-(1-(Dimethylamino)ethyl)benzyl alcohol, Methylephedrine ((1R,2S)-Methylephedrine) 1.0 mg/ml in Methanol, BENZENEMETHANOL, .ALPHA.-((1R)-1-(DIMETHYLAMINO)ETHYL)-, (.ALPHA.S)-REL-, BENZENEMETHANOL, ALPHA-((1S)-1-(DIMETHYLAMINO)ETHYL)-, (.ALPHA.R)-
Theoretical properties:
molecular_formula: C11H17NO
molecular_weight: 179.26 g/mol
exact_mass: 179.131014166 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 3
heavy_atom_count: 13
topological_polar_surface_area: 23.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: (1R,2S)-2-(dimethylamino)-1-phenyl-1-propanol is an alkylbenzene.
chembl: Unnamed Compound is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Methylephedrine, sold under the brand name Metheph among others, is a sympathomimetic medication described as an antiasthmatic agent and used to treat coughing and nasal congestion. It is reported to be used in various over-the-counter cough and cold preparations throughout the world, including Japan.
The drug is an ephedrine-like sympathomimetic and activates α- and β-adrenergic receptors. Chemically, it is a substituted amphetamine and is closely related to ephedrine.
Methylephedrine was discovered by 1927. It is mostly no longer marketed as a prescription drug. The drug is also found naturally as an alkaloid in Ephedra species including Ephedra sinica, Ephedra vulgaris, and Ephedra distachya.