Compound: phenacemide
SMILES: O=C(NC(=O)Cc1ccccc1)N
InChIKey: XPFRXWCVYUEORT-UHFFFAOYSA-N
Synonyms: phenacemide, Phenurone, 63-98-9, Phenylacetylurea, Phenacetylurea, Cetylureum, Phacetur, Phenuron, Epiclase, Fenacemid, Phenacalum, Phenacetur, Phenicarb, Phetylureum, Phenacetylcarbamide, Acetylureum, Carbanmide, Comitiadone, Fenacemide, Fenacetamide, Fenostenyl, Neophenal, Phenarone, Epheron, Felurea, Fenilep, Fenised, Fenural, Fenurea, Fenurone, Fenytan, Phenutal, Phenyrit, (Phenylacetyl)urea, (2-phenylacetyl)urea, Eferon, Phenylacetyluree, Fenacetil-karbamide, Carbamide phenylacetate, Fenacemida, Phenacemidum, Phenacerum, Urea, (phenylacetyl)-, Benzeneacetamide, N-(aminocarbonyl)-, N-(Aminocarbonyl)benzeneacetamide, A-1348, DTXSID6023442, NSC-39458, PAI7J52V09, DTXCID103442, 1-((C-hydroxycarbonimidoyl)imino)-2-phenylethan-1-ol, 1-[(C-hydroxycarbonimidoyl)imino]-2-phenylethan-1-ol, RefChem:55839, 200-570-2, Trioxanona, N-carbamoyl-2-phenylacetamide, Neophedan, Phenacereum, Efron, Fenylacetylmocovina, NSC 39458, .alpha.-Phenylacetylurea, Fenacemide [DCIT], NCGC00094754-01, Phenylacetyluree [French], Fenacemida [INN-Spanish], Phenacemidum [INN-Latin], Fenylacetylmocovina [Czech], amino-N-(2-phenylacetyl)amide, CAS-63-98-9, Phenurone (TN), N-(Phenylacetyl)urea, HSDB 3380, Phenacemide (JAN/INN), EINECS 200-570-2, BRN 2048735, UNII-PAI7J52V09, Phenacemide [USP:INN:BAN], N-(aminocarbonyl)-2-phenylacetamide, Spectrum_000923, N-(Phenylacetyl)urea #, PHENACEMIDE [MI], Spectrum2_001019, Spectrum3_000679, Spectrum4_000473, Spectrum5_001240, PHENACEMIDE [INN], PHENACEMIDE [JAN], WLN: ZVMV1R, PHENACEMIDE [HSDB], CHEMBL918, PHENACEMIDE [VANDF], PHENACEMIDE [MART.], SCHEMBL35118, BSPBio_002377, KBioGR_000946, KBioSS_001403, PHENACEMIDE [WHO-DD], 4-09-00-01636 (Beilstein Handbook Reference), DivK1c_000320, SPECTRUM1500472, SPBio_001177, CHEBI:8049, GTPL7265, SCHEMBL1515664, HMS500P22, KBio1_000320, KBio2_001403, KBio2_003971, KBio2_006539, KBio3_001597, PHENACEMIDE [ORANGE BOOK], NINDS_000320, HMS1920F16, HMS2091N16, Pharmakon1600-01500472, NSC39458, Tox21_111325, CCG-40237, EBC-26136, MSK164431, NSC757266, SBB057962, AKOS009156469, Tox21_111325_1, DB01121, NSC-757266, IDI1_000320, NCGC00094754-02, NCGC00094754-03, NCGC00094754-05, SBI-0051478.P003, DB-054589, NS00035612, ST50825120, C07428, D00504, AB00052068_02, EN300-7476381, SR-05000001694, Q3742404, SR-05000001694-1, BRD-K40905133-001-02-3, BRD-K40905133-001-03-1, BRD-K40905133-001-04-9
Theoretical properties:
molecular_formula: C9H10N2O2
molecular_weight: 178.19 g/mol
exact_mass: 178.074227566 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 2
heavy_atom_count: 13
topological_polar_surface_area: 72.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: CRYSTALS FROM ALCOHOL
color: CRYSTALS FROM ALCOHOL
odor: ODORLESS, OR PRACTICALLY SO
Descriptions:
pubchem: Phenacemide can cause developmental toxicity according to state or federal government labeling requirements.
chembl: PHENACEMIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity.