Compound: chrysin
SMILES: O=c1c2c(oc(c1)-c3ccccc3)cc(O)cc2O
InChIKey: RTIXKCRFFJGDFG-UHFFFAOYSA-N
Synonyms: chrysin, 480-40-0, 5,7-Dihydroxyflavone, Chrysine, 5,7-dihydroxy-2-phenylchromen-4-one, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl-, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, FLAVONE, 5,7-DIHYDROXY-, NSC-407436, DTXSID1022396, 3CN01F5ZJ5, DTXCID902396, CHEBI:75095, 5,7-dihydroxy-flavone, RefChem:5686, 207-549-7, 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one, MFCD00006834, 5,7-Dihydroxy-2-phenyl-chromen-4-one, NSC407436, CHEMBL117, Crysin, 5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one, Chrysin 99+%, CAS-480-40-0, Chrysinic acid, SMR000112318, SR-01000765660, EINECS 207-549-7, NSC 407436, BRN 0233276, UNII-3CN01F5ZJ5, Chrysinic acid;, 3ebo, 4des, 5,7-flavonone, 57D, Chrysin (Standard), 5,7-diOH-Flavone, Flavone,7-dihydroxy-, Chrysin, 97%, 5,7-dihydroxy flavone, Ois 3, Spectrum_000245, CHRYSIN [MI], Prestwick0_000889, Prestwick1_000889, Prestwick2_000889, Prestwick3_000889, Spectrum2_000753, Spectrum3_001399, Spectrum4_000780, Spectrum5_001503, Chrysin, analytical standard, Oprea1_045160, SCHEMBL44474, BSPBio_000678, BSPBio_002514, BSPBio_003018, KBioGR_001200, KBioSS_000725, 5-18-04-00076 (Beilstein Handbook Reference), MLS000697728, MLS001074879, MLS006011841, BIDD:ER0484, DivK1c_000614, SPECTRUM1500709, SPECTRUM1505144, SPBio_000766, SPBio_002897, AKOS NCG1-0026, BDBM7461, BPBio1_000746, GTPL8789, MEGxp0_001416, orb1304954, orb3139465, SCHEMBL28586240, SCHEMBL29383577, ACon1_000087, cid_5281607, HMS501O16, KBio1_000614, KBio2_000725, KBio2_003293, KBio2_005861, KBio3_002238, MSK7407, NINDS_000614, HMS1570B20, HMS1921E20, HMS2097B20, HMS2268I23, HMS3468N08, HMS3655L20, ALBB-015581, Tox21_302335, BBL010449, CCG-40148, EBC-13872, HY-14589R, LMPK12110189, NSC818102, NSC843015, s2281, SBB012459, STK801609, AKOS000275936, CS-7531, DB15581, FD30010, GS-0927, NSC-818102, NSC-843015, SDCCGMLS-0066586.P001, IDI1_000614, SMP1_000070, NCGC00016456-01, NCGC00016456-02, NCGC00016456-03, NCGC00016456-04, NCGC00016456-05, NCGC00016456-06, NCGC00016456-07, NCGC00016456-08, NCGC00016456-09, NCGC00016456-10, NCGC00016456-12, NCGC00094842-01, NCGC00094842-02, NCGC00094842-03, NCGC00094842-04, NCGC00094842-05, NCGC00168807-01, NCGC00168807-02, NCGC00168807-03, NCGC00168807-04, NCGC00255307-01, AC-10052, HY-14589, NCI60_003886, ST069324, SY050125, AB00513947, C1652, NS00008874, SW197197-2, 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one #, 4H-1-Benzopyran-4-one,7-dihydroxy-2-phenyl-, EN300-303044, S00112, Chrysin 1000 microg/mL in Acetonitrile:Methanol, AK-693/40848576, F370625, Q973741, SR-01000765660-3, SR-01000765660-4, 34B3B4AD-EEDD-4943-A1C6-8857D2FAA8E0, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, 9CI, BRD-K22861715-001-07-5, BRD-K22861715-001-12-5, BRD-K22861715-001-17-4, Z1824566175
Theoretical properties:
molecular_formula: C15H10O4
molecular_weight: 254.24 g/mol
exact_mass: 254.05790880 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 1
heavy_atom_count: 19
topological_polar_surface_area: 66.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 285.50 °C. @ 760.00 mm Hg
Descriptions:
pubchem: Chrysin is a dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. It has a role as an antioxidant, an antineoplastic agent, a hepatoprotective agent, an anti-inflammatory agent, a plant metabolite and an EC 2.7.11.18 (myosin-light-chain kinase) inhibitor. It is a dihydroxyflavone and a 7-hydroxyflavonol.
chebi: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.
chembl: CHRYSIN is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Chrysin, also called 5,7-dihydroxyflavone, is a flavone found in honey, propolis, the passion flowers, Passiflora caerulea and Passiflora incarnata, and in Oroxylum indicum. It is extracted from various plants, such as the blue passion flower (Passiflora caerulea). Following oral intake by humans, chrysin has low bioavailability and rapid excretion. It is under basic research to evaluate its safety and potential biological effects.
Chrysin is an ingredient in dietary supplements. As of 2016, there was no clinical use of chrysin, and no evidence for its effect on testosterone levels. In 2016, the US Food and Drug Administration did not recommend chrysin be included on the list of bulk drug substances that can be used in compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.