Compound: 8-AZAGUANINE
SMILES: O=c1nc(nc2-c1n[nH][nH]2)N
InChIKey: LPXQRXLUHJKZIE-UHFFFAOYSA-N
Synonyms: 8-AZAGUANINE, 134-58-7, Azaguanine-8, Guanazolo, Azaguanine, Pathocidin, Guanazol, Pathocidine, Triazologuanine, NSC-749, SK 1150, 5-Amino-1H-v-triazolo(d)pyrimidin-7-ol, SF-337, 5-Amino-7-hydroxy-1H-v-triazolo(d)pyrimidine, NSC749, CHEBI:63486, 5-Amino-1,6-dihydro-7H-v-triazolo(4,5-d)pyrimidin-7-one, 5-Amino-1,4-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one, DTXSID0074508, 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-1,4-dihydro-, NSC223526, NSC-223526, 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,4-dihydro-, Q150359I72, 5-Amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 3-amino-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one, 8 Azaguanine, 3-amino-2,4,7,8,9-pentazabicyclo(4.3.0)nona-1,3,6-trien-5-one, 5-amino-3,6-dihydro-7H-(1,2,3)triazolo(4,5-d)pyrimidin-7-one, RefChem:388816, DTXCID1034181, 205-148-1, Azan, 8 AG, C4H4N6O, 5-Amino-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one, 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one, AZG, MFCD00056937, 2-Amino-6-hydroxy-8-azapurine, 5-Amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol, 1850358-61-0, NSC 223526, B-28, AZAGUANINE,8, v-Triazolo(4,5-d)pyrimidin-7-ol, 5-amino-, 5-amino-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one, MLS001074752, 5-amino-1H-triazolo[4,5-d]pyrimidin-7-ol, ML068, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, SMR000112575, 7H-v-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,6-dihydro-, 5-Amino-1H-triazolo(4,5-d)pyrimidin-7-ol, v-Triazolo[4, 5-amino-, 3H-1,2,3-triazolo[4,5-d]pyrimidin-7-ol, 5-amino-, 5-imino-4,6-dihydro-3H-1,2,3-triazolo[5,4-d]pyrimidin-7-one, WLN: T56 BNNM FVM INJ HZ, 5-Amino-1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 5-AMINO-3,6-DIHYDRO-(1,2,3)TRIAZOLO(4,5-D)PYRIMIDIN-7-ONE, 2-Amino-6-oxy-8-azapurine, 7H-v-Triazolo[4, 5-amino-1,6-dihydro-, CCRIS 2758, 8-AzaG, NSC 749, EINECS 205-148-1, 5-AMINO-2,3-DIHYDROTRIAZOLO(4,5-D)PYRIMIDIN-7-ONE, 7H-1,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-1,4-dihydro-, AI3-25015, 8-azaguanin, Azaguanine, 8, Prestwick_40, UNII-Q150359I72, 5-Amino-3,6-dihydro-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one; Azaguanine; Azan; Guanazol; Guanazolo; Pathocidin, 8AZAG, Prestwick0_000001, Prestwick1_000001, Prestwick2_000001, Prestwick3_000001, Epitope ID:167837, NCIMech_000065, cid_8646, 8-AZAGUANINE [MI], Oprea1_163604, Oprea1_695327, Oprea1_862850, SCHEMBL26816, SCHEMBL26817, SCHEMBL26818, BSPBio_000001, SPBio_001922, BPBio1_000003, CHEMBL374107, orb1306075, SCHEMBL2934835, SCHEMBL2934836, SCHEMBL6055297, SCHEMBL6154666, SCHEMBL6154668, SCHEMBL6322310, SCHEMBL16056969, SCHEMBL29437835, BDBM96998, 8-Azaguanine(10 mM in DMSO), 8-Azaguanine - Bio-X trade mark, GLXC-02309, GLXC-22934, HMS1568A03, HMS2095A03, HMS2269M18, HMS3652J09, HMS3712A03, 7H-1,2,3-Triazolo(4,5-d)pyrimidinone, 5-amino-1,4-dihydro-, ALBB-023426, HY-B1468, BDBM50465709, CCG-35353, s4194, SBB000107, STK961684, AKOS002271137, AKOS003382261, AKOS006223655, AKOS015854480, AKOS026750385, CCG-220001, DB01667, EBC-616291, FA07970, s11846, NCGC00016399-01, NCGC00016399-03, NCGC00188264-01, BA300017, DS-16103, NCI60_041639, ST025228, ST088035, SY052313, DB-350879, A0625, CS-0013169, CS-0513856, NS00021613, SW196356-3, AP-770/40205766, F219608, SR-01000763820, 5-amino-1,6-dihydrotriazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydrotriazolo[4,5-d]pyrimidin-7-one, 5-amino-3H-1,2,3-triazolo[5,4-d]pyrimidin-7-ol, Q4644262, SR-01000763820-2, BRD-K53114651-001-11-9, BRD-K53114651-001-12-7, 5-Amino-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7(3H)-one, 1,2,3-Triazolo(5',4'-4,5)pyrimidine, 2-amino-6-hydroxy-, 5-Amino-1H-[1,2,3]triazolo-[4,5-d]pyrimidin-7(6H)-one, 5-amino-3H,4H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 5-azanyl-2,3-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 5-azanyl-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, {7H-v-Triazolo[4,5-d]pyrimidin-7-one,} 5-amino-1, 6-dihydro-, 5-Amino-1,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 5-Amino-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one #, 7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-, {7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,} 5-amino-1,4-dihydro-, 5-imino-3,4,5,6-tetrahydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 5-imino-5,6-dihydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one, 8-Azaguanine, Hybri-Max(TM), gamma-irradiated, powder, BioXtra, suitable for hybridoma, 9QC
Theoretical properties:
molecular_formula: C4H4N6O
molecular_weight: 152.11 g/mol
exact_mass: 152.04465877 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 3
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 0
heavy_atom_count: 11
topological_polar_surface_area: 109 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
solubility: Insoluble
Descriptions:
pubchem: 8-azaguanine is a triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively. It has a role as an antimetabolite, an antineoplastic agent and an EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor. It is a member of triazolopyrimidines and a nucleobase analogue.
chebi: A triazolopyrimidine that consists of 3,6-dihydro-7<em>H</em>-[1,2,3]triazolo[4,5-<em>d</em>]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively.
chembl: 8-AZAGUANINE is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: 8-Azaguanine is a purine analog with the chemical formula C4H4N6O. It has been widely studied for its biological activity. It shows antineoplastic activity and has been used in the treatment of acute leukemia.