Compound: nylidrin
SMILES: Oc1ccc(C(O)C(NC(CCc2ccccc2)C)C)cc1
InChIKey: PTGXAUBQBSGPKF-UHFFFAOYSA-N
Synonyms: nylidrin, Buphenine, 447-41-6, Buphenin, Nilidrine, Suprifen-psb, Bufenina, Bupheninum, Phenyl-sec-butyl norsuprifen, 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol, 695DKH33EI, p-Hydroxy-N-(1-methyl-3-phenylpropyl)norephedrine, DTXSID4023387, Benzenemethanol, 4-hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-, 1-(p-Hydroxyphenyl)-2-(1'-methyl-3'-phenylpropylamino)-1-propanol, DTXCID103387, 4-Hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)benzenemethanol, p-Hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)benzyl alcohol, Benzyl alcohol, p-hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-, Bufenine, 4-(1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl)phenol, RefChem:166996, C04AA02, G02CA02, 207-182-2, 4-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]propyl}phenol, Buphenine (INN), 4-(1-Hydroxy-2-((4-phenylbutan-2-yl)amino)propyl)phenol, NCGC00015716-05, Nylidrinum, BUPHENINE [INN], 4-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]propyl}phenol, Bufenina [INN-Spanish], Bupheninum [INN-Latin], Benzenemethanol, 4-hydroxy-.alpha.-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]-, CAS-447-41-6, HSDB 3137, Buphenine [INN:BAN], SKF 1700-A, EINECS 207-182-2, CS 6712, UNII-695DKH33EI, SR-01000002981, BENZENEMETHANOL, 4-HYDROXY-.ALPHA.-(1-((1-METHYL-3-PHENYLPROPYL)AMINO)ETHYL)-, Spectrum_001043, NYLIDRIN [HSDB], NYLIDRIN [MI], NYLIDRIN [VANDF], Spectrum2_000967, Spectrum3_000529, Spectrum4_000458, Spectrum5_000996, BUPHENINE [WHO-DD], Lopac0_000911, BSPBio_002117, KBioGR_000876, KBioSS_001523, DivK1c_000109, SCHEMBL159150, SPBio_000973, CHEMBL114655, orb1740241, CHEBI:91656, KBio1_000109, KBio2_001523, KBio2_004091, KBio2_006659, KBio3_001617, NINDS_000109, HMS3714L05, Tox21_110204, EBC-26523, MFCD00599550, AKOS003368108, Tox21_110204_1, CCG-204993, DB06152, SDCCGSBI-0050886.P005, IDI1_000109, SMP1_000218, NCGC00015716-03, NCGC00015716-04, NCGC00015716-07, NCGC00015716-08, NCGC00015716-09, NCGC00015716-13, NCGC00089743-02, NCGC00089743-03, SBI-0050886.P004, CS-0085441, NS00010342, D07551, E75906, AB00053509-11, AB00053509_12, AO-080/40212238, EN300-18559873, Q851507, SR-01000002981-6, BRD-A36267905-003-12-7, BRD-A36267905-003-18-4, BRD-A36267905-003-19-2, 4-(1-Hydroxy-2-[(1-methyl-3-phenylpropyl)amino]propyl)phenol #, 4-[1-hydroxy-2-[(1-methyl-3-phenyl-propyl)amino]propyl]phenol, 4-(1-HYDROXY-2-(1-METHYL-3-PHENYL-PROPYLAMINO)-PROPYL)-PHENOL, p-Hydroxy-.alpha.-[1-[(methyl-3-phenylpropyl)amino]ethyl]benzyl alcohol, Benzyl alcohol, p-hydroxy-.alpha.-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]-, P-HYDROXY-.ALPHA.-(1-((1-METHYL-3-PHENYLPROPYL)AMINO)ETHYL)BENZYL ALCOHOL
Theoretical properties:
molecular_formula: C19H25NO2
molecular_weight: 299.4 g/mol
exact_mass: 299.188529040 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 3
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 7
heavy_atom_count: 22
topological_polar_surface_area: 52.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Crystals from methanol
color: Crystals from methanol
odor: ODORLESS
solubility: Mol wt 335.88. Crystals. Sparingly sol in water; slightly sol in alcohol. Practically insol in ether, chloroform, benzene /Hydrochloride/
Descriptions:
pubchem: 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol is an alkylbenzene.
chembl: NYLIDRIN is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Buphenine, also known as nylidrin and sold under the brand name Arlidin, is a β2 adrenoreceptor agonist that acts as a vasodilator.
It was developed as a chemical derivative of oxilofrine, and first reported in the literature in 1950.