Compound: tetroquinone
SMILES: O=C1C(O)=C(O)C(=O)C(=C1O)O
InChIKey: DGQOCLATAPFASR-UHFFFAOYSA-N
Synonyms: tetroquinone, 319-89-1, 2,3,5,6-tetrahydroxycyclohexa-2,5-diene-1,4-dione, Tetrahydroxy-p-benzoquinone, Tetroquinona, Tetrahydroxy-p-quinone, HPEK-1, Tetroquinonum, Tetrahydroxyparabenzoquinone, Tetrochinone, 2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrahydroxy-, 2,3,5,6-Tetrahydroxy-p-benzoquinone, NSC-112931, U7L4P6H0SU, DTXSID9045897, DTXCID7025897, RefChem:1099699, 206-275-5, Tetrahydroxyquinone, Tetrahydroxy-1,4-benzoquinone, Kelox, Terasin, Tetrahydroxy-1,4-quinone, 2,3,5,6-tetrahydroxy-1,4-benzoquinone, MFCD00001597, NSC112931, NCGC00095043-01, p-Benzoquinone, 2,3,5,6-tetrahydroxy-, Tetrahydroxy-1,4-benzoquinone;Tetrahydroxybenzoquinone, Tetrahydroxy-1,4-quinone hydrate, C6H4O6, Tetrochinone [DCIT], CAS-319-89-1, Tetroquinone [USAN:INN], UNII-U7L4P6H0SU, Tetroquinonum [INN-Latin], Tetroquinona [INN-Spanish], Tetraoxychinon, SR-05000002066, tetrahydroxy quinone, EINECS 206-275-5, NSC 112931, Spectrum_001691, Prestwick0_000835, Prestwick1_000835, Prestwick2_000835, Prestwick3_000835, Spectrum2_000866, Spectrum3_000750, Spectrum4_000847, Spectrum5_001627, TETROQUINONE [MI], Tetroquinone (USAN/INN), TETROQUINONE [INN], TETROQUINONE [USAN], BSPBio_000789, BSPBio_002340, KBioGR_001453, KBioSS_002171, DivK1c_000623, SCHEMBL167587, SPECTRUM1503330, SPBio_000911, SPBio_002710, 2,3,5,6-Tetrahydroxy-2,5-cyclohexadiene-1,4-dione, BPBio1_000869, orb1310818, SCHEMBL4657549, CHEMBL1329029, HMS501P05, KBio1_000623, KBio2_002171, KBio2_004739, KBio2_007307, KBio3_001560, CHEBI:137472, NINDS_000623, HMS1922A16, HMS2093E07, HMS6018C22, Pharmakon1600-01503330, 2,5,6-Tetrahydroxy-p-benzoquinone, HY-B1106, Tox21_111400, CCG-39742, NSC758457, p-Benzoquinone,3,5,6-tetrahydroxy-, STL453704, AKOS006228209, Tox21_111400_1, CS-4703, DS-3819, FT61735, NSC-758457, 2,4-dione, 2,3,5,6-tetrahydroxy-, IDI1_000623, NCGC00095043-02, NCGC00095043-03, NCGC00095043-04, NCGC00095043-07, 2,3,5,6-Tetrahydroxybenzo-1,4-quinone, AC-18203, 2,3,5,6-tetrahydroxy-[1,4]benzoquinone, SBI-0051815.P002, DB-068561, 1,4-Benzoquinone, 2,3,5,6-tetrahydroxy-, 2,3,5,6-Tetrahydroxybenzo-1,4-quinone #, NS00029202, ST50410481, D06096, F17741, AB00052347_04, F241261, Q3546866, SR-05000002066-1, 2,3,5,6-Tetrahydroxy-2,5-cyclohexadien-1,4-dione
Theoretical properties:
molecular_formula: C6H4O6
molecular_weight: 172.09 g/mol
exact_mass: 172.00078784 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 4
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 0
heavy_atom_count: 12
topological_polar_surface_area: 115 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Tetrahydroxy-1,4-benzoquinone is a hydroxybenzoquinone in which all four protons of the benzoquinone structure are substituted by hydroxy groups. A systemic keratolytic, it is normally supplied as its hydrate (CHEBI:137471). It has a role as a keratolytic drug.
chebi: A hydroxybenzoquinone in which all four protons of the benzoquinone structure are substituted by hydroxy groups. A systemic keratolytic, it is normally supplied as its hydrate (CHEBI:137471).
chembl: TETROQUINONE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Tetrahydroxy-1,4-benzoquinone, also called tetrahydroxy-p-benzoquinone, tetrahydroxybenzoquinone, or tetrahydroxyquinone (THBQ, THQ), is an organic compound with formula C6O2(OH)4.  Its molecular structure consists of a cyclohexadiene ring with four hydroxyl groups and two ketone groups in opposite (para) positions.
The compound gives a light red solution in water, and crystallizes as the glistening bluish-black (but non-conducting) dihydrate C6O2(OH)4·2H2O.
The compound can be synthesized from glyoxal or from myo-inositol, a natural compound widely present in plants.  THBQ forms an adduct with 4,4′-bipyridine in a 2:3 ratio.