Compound: Pheneturide
SMILES: O=C(NC(=O)C(c1ccccc1)CC)N
InChIKey: AJOQSQHYDOFIOX-UHFFFAOYSA-N
Synonyms: Pheneturide, 2-Phenylbutyrylurea, 90-49-3, Ethylphenacemide, Benuride, Ethylphenylacetylurea, Lircapyl, Phenuride, Phenylethylacetylurea, dl-Pheneturide, Laburide, Feneturida, 1-((Ethyl)phenylacetyl)urea, Pheneturidum, Urea, (2-phenylbutyryl)-, N-(alpha-Phenylbutyryl)urea, N-carbamoyl-2-phenyl-butanamide, 878CEJ4HGX, DTXSID4020612, M-551, DTXCID40612, (2-phenylbutyryl)urea, ethyl phenacemide, RefChem:860599, N03AX13, 201-998-2, N-carbamoyl-2-phenylbutanamide, (2-phenylbutanoyl)urea, Phenylethylacetyluree, S 46, M 551, PBU, S-46, N-(.alpha.-Phenylbutyryl)urea, 6509-31-5, Pheneturide (INN), MFCD00069050, NCGC00180997-01, Ethylphenacemide (JAN), d-Pheneturide, l-Pheneturide, Phenylethylacetylurea (2-Phenylbutyrylurea), PHENETURIDE [INN], Aethylphenacemidum, (+)-Pheneturide, (-)-Pheneturide, Benuride; EPA; Ethylphenacemide; Lircapyl; M 551, Benzeneacetamide, N-(aminocarbonyl)-.alpha.-ethyl-, ETHYLPHENACEMIDE [JAN], Pheneturide [INN:BAN], Feneturida [INN-Spanish], Pheneturidum [INN-Latin], CAS-90-49-3, Phenylethylacetyluree [French], CCRIS 3075, EINECS 201-998-2, Urea, (2-phenylbutyryl)-, (+)-, Urea, (2-phenylbutyryl)-, (-)-, UNII-878CEJ4HGX, N-(Aminocarbonyl)-alpha-ethylbenzeneacetamide (+)-, N-(Aminocarbonyl)-alpha-ethylbenzeneacetamide (-)-, N-(aminocarbonyl)-2-phenylbutanamide, Benzeneacetamide, N-(aminocarbonyl)-alpha-ethyl-, (+)-, Benzeneacetamide, N-(aminocarbonyl)-alpha-ethyl-, (-)-, N-CARBAMOYL-2-PHENYL BUTANAMIDE, Pheneturide (Standard), PHENETURIDE [MI], Phenobarbital Impurity 10, PHENETURIDE [MART.], SCHEMBL35066, PHENETURIDE [WHO-DD], 6192-36-5, MLS006010403, N-(2-Phenylbutanoyl)urea #, orb1298800, CHEMBL2107062, CHEBI:31989, AAA09049, Tox21_112650, Tox21_302208, EBC-13232, AKOS011976695, DB13362, HY-111177R, NCGC00255213-01, 6509-32-6, MS-23123, SMR001798871, SY152566, HY-111177, CS-0034531, NS00039361, .ALPHA.-PHENYL-.ALPHA.-ETHYLACETYLUREA, D01190, EN300-136805, F88147, SBI-0654658.0001, F601397, SR-01000944857, Q7181340, SR-01000944857-1, Z995154698
Theoretical properties:
molecular_formula: C11H14N2O2
molecular_weight: 206.24 g/mol
exact_mass: 206.105527694 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 3
heavy_atom_count: 15
topological_polar_surface_area: 72.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Pheneturide is an amine.
chembl: PHENETURIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. Conceptually, it can be formed in the body as a metabolic degradation product from phenobarbital. It is considered to be obsolete and is now seldom used. It is marketed in Europe, including in Poland, Spain and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide. As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed. Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.