Compound: naftopidil
SMILES: O(c1c2c(ccc1)cccc2)CC(O)CN3CCN(c4c(OC)cccc4)CC3
InChIKey: HRRBJVNMSRJFHQ-UHFFFAOYSA-N
Synonyms: naftopidil, 57149-07-2, Flivas, Naftopidilum, 1-(4-(2-methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol, DTXSID5045176, R9PHW59SFN, NSC-759293, DTXCID3025176, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-(naphthalen-1-yloxy)propan-2-ol, 1-(4-(2-methoxyphenyl)-1-piperazinyl)-3-(1-naphthyloxy)-2-propanol, 1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthyloxy)-2-propanol, RefChem:831691, (2RS)-1-(4-(2-Methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol, Avishot, KT-611, Naftopidil [INN], 4-(2-methoxyphenyl)-alpha-[(1-naphthalenyloxy)methyl]-1-piperazineethanol, MFCD00242741, (+/-)-Naftopidil, BM-15275, CHEMBL142635, NCGC00015718-06, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-(1-naphthyloxy)propan-2-ol, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol, Naftopidilum [Latin], Naftopidil hydrochloride hydrate, SMR000466346, CAS-57149-07-2, UNII-R9PHW59SFN, BRN 0629965, Avishot;, Flivas (TN), Naftopidil (Flivas), Naftopidil (Standard), NAFTOPIDIL [MI], NAFTOPIDIL [JAN], Prestwick0_000975, Prestwick1_000975, Prestwick2_000975, Prestwick3_000975, (+-)-1-(4-(2-Methoxyphenyl)piperazinyl)-3-(1-naphthyloxy)propan-2-ol, Naftopidil (JP18/INN), (RS)-1-(4-(2-methoxyphenyl)-1-piperazinyl)-3-(1-naphthyloxy)-2-propanol, 4-(2-Methoxyphenyl)-alpha-((1-naphthalenyloxy)methyl)-1-pioerazineethanol, cid_4418, NAFTOPIDIL [MART.], NAFTOPIDIL [WHO-DD], Lopac0_000941, REGID_for_CID_4418, BSPBio_001009, MLS000759459, MLS001424117, SCHEMBL113215, SPBio_002920, BPBio1_001111, Naftopidil - Bio-X trade mark, orb1310376, SCHEMBL29449978, BDBM50773, CHEBI:31891, cid_6603044, HY-B0391R, HMS2051B09, HMS2089G07, HMS3393B09, HMS3655H21, HMS3884P07, HMS5080K14, Pharmakon1600-01506024, HY-B0391, Tox21_110205, BBL028454, EBC-03851, MFCD11046013, MSK163437, NSC759293, s2126, STL372645, (+-)-4-(o-Methoxyphenyl)-alpha-((1-naphthyloxy)methyl)-1-piperazineethanol, 1-Pioerazineethanol, 4-(2-methoxyphenyl)-alpha-((1-naphthalenyloxy)methyl)-, AKOS002279617, AKOS016328058, Tox21_110205_1, CCG-100935, CCG-205022, DB12092, FE-0209, FN26123, NC00185, NSC 759293, SB19321, SDCCGSBI-0050915.P003, NCGC00015718-04, NCGC00015718-05, NCGC00015718-08, NCGC00015718-09, NCGC00015718-10, NCGC00015718-12, NCGC00015718-25, NCGC00024672-03, NCGC00024672-04, BN164631, SY053735, SBI-0050915.P002, AB00514643, N0832, ST50794017, SW196570-4, T0696, D01674, AB00489961-18, AB00489961-19, AB00489961_20, AB00489961_21, EN300-6492981, F463444, Q6958243, BRD-A01787639-001-06-4, BRD-A01787639-001-07-2, BRD-A01787639-001-08-0, BRD-A01787639-003-16-9, BRD-A01787639-300-03-7, BRD-A01787639-300-04-5, BRD-A01787639-300-08-6, BRD-A01787639-300-09-4, Z31369389, 1-[4-(2-methoxyphenyl)piperazinyl]-3-naphthyloxypropan-2-ol, 1-[4-(2-Methoxyphenyl)piperazinyl]-3-(1-naphthyloxy)propan-2-ol, 1-[4-(2-methoxyphenyl)piperazino]-3-(1-naphthoxy)propan-2-ol;hydrochloride, 4-(2-Methoxyphenyl)-?-[(1-naphthalenyloxy)methyl]-1-piperazineethanol, (+/-)-4-(O-METHOXYPHENYL)-.ALPHA.-((1-NAPHTHYLOXY)METHYL)-1-PIPERAZINEETHANOL, 1-[4-(2-methoxyphenyl)-1-piperazinyl]-3-(1-naphthalenyloxy)-2-propanol;hydrochloride, 1-[4-(2-Methoxyphenyl)piperazin-1-yl]-3-[(naphthalen-1-yl)oxy]propan-2-ol, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxy-propan-2-ol;hydrochloride, 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol;hydrochloride, 4-(2-Methoxyphenyl)-alpha-[(1-naphthalenyloxy)methyl]-1-piperazineethanol hydrochloride hydrate
Theoretical properties:
molecular_formula: C24H28N2O3
molecular_weight: 392.5 g/mol
exact_mass: 392.20999276 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 7
heavy_atom_count: 29
topological_polar_surface_area: 45.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Naftopidil is a member of piperazines.
chembl: NAFTOPIDIL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Naftopidil (INN, marketed under the brand name Flivas) is a drug used in benign prostatic hyperplasia which acts as a selective α1-adrenergic receptor antagonist or alpha-1 blocker.