Compound: Harman
SMILES: n1c(c2[nH]c3ccccc3c2cc1)C
InChIKey: PSFDQSOCUJVVGF-UHFFFAOYSA-N
Synonyms: Harman, HARMANE, 486-84-0, 1-Methyl-9H-pyrido[3,4-b]indole, Aribine, Locuturine, Loturine, Aribin, Passiflorin, 1-Methylnorharman, Locuturin, 1-Methyl-beta-carboline, 9H-Pyrido[3,4-b]indole, 1-methyl-, 1-methyl-2-carboline, 9H-Pyrido(3,4-b)indole, 1-methyl-, 1-Methyl-9H-pyrido(3,4-b)indole, NSC-54439, 82D6J0535P, CHEBI:5623, DTXSID80197568, RefChem:145268, DTXCID40120059, 207-642-2, 1-Methyl-9H-beta-carboline, 3-Methyl-4-carboline, PYRIDOBINDOLE, L-METHYL-, MFCD00004957, methylbeta-carboline, NSC 54439, 1-Methyl-.beta.-carboline, CHEMBL12014, NSC54439, ST013856, Harman-d3 (Major), Harman-13C2,15N, Passiflorin-13C2,15N, Zygofabagine, 1-Methyl-9H-pyrid(3,4-b)indole, 1-Methyl-9H-pyrid[3,4-b]indole, CCRIS 6419, 1189461-56-0, SR-01000075915, EINECS 207-642-2, BRN 0143898, Passiflorine, UNII-82D6J0535P, CN9, Harmane, free base, Harmane (Standard), L-methylpyridobindole, 2-Methyl-b-carboline, Harmane, 98%, L-Methyl-Pyridobindole, Spectrum_001126, Tocris-1132, SpecPlus_000609, Prestwick0_000620, Prestwick1_000620, Prestwick2_000620, Prestwick3_000620, Spectrum3_000905, Spectrum4_001003, HARMAN [MI], Lopac-H-7258, Lopac0_000605, Oprea1_152883, BSPBio_000560, KBioGR_001465, KBioSS_001606, 5-23-08-00261 (Beilstein Handbook Reference), MLS001173587, DivK1c_006705, SCHEMBL141723, SCHEMBL195100, SPECTRUM1500866, SPBio_002779, 1-Methyl-9H-I(2)-carboline, BPBio1_000616, orb1304479, orb3141476, SCHEMBL1226266, 1-Methyl-9H-beta-carboline #, SCHEMBL27891345, SCHEMBL29630272, cid_5281404, KBio1_001649, KBio2_001606, KBio2_004174, KBio2_006742, KBio3_001850, HMS2858P09, HMS3261J12, HMS3267O04, HMS3412K19, HMS3676K19, HMS6018A08, WLN: T B656 EN HMJ F, ALBB-009251, MSK10743, Tox21_500605, BDBM50013786, EX-A12282, HB1665, SBB003735, STK501254, 1-Methyl-9H-Pyrido[3,4-6]indole, 1-Methyl-9H-beta-carboline (Harman), AKOS002664659, CCG-204694, EBC-428049, FH23738, HY-101392R, LP00605, SDCCGMLS-0066938.P001, SDCCGSBI-0050587.P003, NCGC00015514-01, NCGC00015514-02, NCGC00015514-03, NCGC00015514-04, NCGC00015514-05, NCGC00015514-06, NCGC00015514-07, NCGC00015514-08, NCGC00015514-09, NCGC00015514-10, NCGC00015514-16, NCGC00025022-01, NCGC00025022-02, NCGC00025022-03, NCGC00025022-04, NCGC00025022-05, NCGC00025022-06, NCGC00261290-01, AC-15673, AS-42735, SMR000538681, SY380110, 1-Methyl-9H-pyrido[3,4-b]indole, 9CI, CAS-21655-84-5, HY-101392, AB00052849, CS-0021283, EU-0100605, NS00014584, C09209, H 7258, H-1150, F367646, SR-01000075915-1, SR-01000075915-7, SR-01000075915-8, BRD-K12630395-001-14-9, BRD-K12630395-003-03-8, Q15411006, InChI=1/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H
Theoretical properties:
molecular_formula: C12H10N2
molecular_weight: 182.22 g/mol
exact_mass: 182.084398327 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 1
rotatable_bond_count: 0
heavy_atom_count: 14
topological_polar_surface_area: 28.7 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 237 - 238 °C
Descriptions:
pubchem: Harman is an indole alkaloid fundamental parent with a structure of 9H-beta-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor, an anti-HIV agent and a plant metabolite. It is an indole alkaloid fundamental parent, an indole alkaloid and a harmala alkaloid.
chebi: An indole alkaloid fundamental parent with a structure of 9<em>H</em>-β-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of <em>Sickingia rubra</em>, <em>Symplocus racemosa</em>, <em>Passiflora incarnata</em>, <em>Peganum harmala</em>, <em>Banisteriopsis caapi</em> and <em>Tribulus terrestris</em>, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A.
chembl: HARMAN is a small molecule listed in the ChEMBL database but has not progressed to an approved clinical phase.
wikipedia: Harman International Industries, Inc., commonly known as Harman, is an American audio electronics company. Since 2017, the company has been operating as an independent subsidiary of Samsung Electronics.
Headquartered in Stamford, Connecticut, US, it has its own executive leadership team. Harman maintains major operations in the Americas, Europe, and Asia. Harman markets its products under various brands, including AKG, AMX, Arcam, Becker, Boston Acoustics, Bowers & Wilkins, BSS Audio, Classé, Crown, dbx, Definitive Technology, Denon, DigiTech, Harman Kardon, HEOS, Infinity, JBL, Lexicon, Mark Levinson, Marantz, Martin, Polk Audio, Revel, Soundcraft and Studer.