Compound: piribedil
SMILES: O1c2c(ccc(c2)CN3CCN(c4ncccn4)CC3)OC1
InChIKey: OQDPVLVUJFGPGQ-UHFFFAOYSA-N
Synonyms: piribedil, 3605-01-4, Trivastal, 2-(4-Piperonyl-1-piperazinyl)pyrimidine, ET-495, EU-4200, 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine, ET 495, Piribedilum, EU 4200, DO22K1PRDJ, DTXSID9045188, DTXCID7025188, Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-, Piribendyl, Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)-, 2-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl)pyrimidine, Trivastal lp, 2-(4-((2H-1,3-benzodioxol-5-yl)methyl)piperazin-1-yl)pyrimidine, RefChem:174519, Piribedil Mono hydrochloride, Mono-hydrochloride, Piribedil, N04BC08, ET495, EU4200, 222-764-6, Trivastan, 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine, MFCD00868264, 1-(2-Pyrimidyl)-4-piperonylpiperazine, Pyrimidine, 2-(4-piperonyl-1-piperazinyl)-, Piribedil (INN), 2-(4-(3,4-Methylenedioxybenzyl)piperazino)pyrimidine, 1-(3,4-Methylenedioxybenzyl)-4-(2-pyrimidyl)piperazine, NCGC00015857-05, 2-(4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl)pyrimidine, PIRIBEDIL [INN], 2-(4-(Benzo[d][13]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine, 2-[4-(2H-1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine, CAS-3605-01-4, Piribedile [DCIT], Piribedil [INN:DCF], Piribedilum [INN-Latin], Piribedile, SR-01000076091, Trivastal (TN), EINECS 222-764-6, Piribedil (Standard), BRN 0963637, Tocris-1031, PIRIBEDIL [MI], Prestwick0_000980, Prestwick1_000980, Prestwick2_000980, Prestwick3_000980, UNII-DO22K1PRDJ, Lopac-P-9233, Biomol-NT_000044, GTPL49, PIRIBEDIL [MART.], Cambridge id 5268291, PIRIBEDIL [WHO-DD], Lopac0_000965, Oprea1_061309, Oprea1_215383, BSPBio_001019, SCHEMBL150101, SPBio_002930, BPBio1_001121, BPBio1_001269, orb1304353, CHEMBL1371770, SCHEMBL29359749, BDBM85092, CHEBI:92833, 2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-pyrimidine, HMS2089M17, HMS3885E19, HMS5081P14, NSC_4850, Tox21_110245, EBC-07123, HY-12707R, s3656, STL497889, AKOS001309525, Tox21_110245_1, AC-1051, CCG-205045, CS-8014, DB12478, ES-0016, FP65134, SDCCGSBI-0050938.P003, NCGC00015857-01, NCGC00015857-02, NCGC00015857-03, NCGC00015857-04, NCGC00015857-06, NCGC00015857-07, NCGC00015857-09, NCGC00015857-16, NCGC00024951-01, NCGC00024951-02, NCGC00024951-03, DA-66746, HY-12707, CAS_3605-01-4, SBI-0050938.P002, CAS-78213-63-5, AB00514645, NS00008358, P2054, D07305, T72361, AB00514645-19, EN300-6492984, AG-690/37046188, F241812, L000476, Q413976, BRD-K47936004-001-01-9, BRD-K47936004-003-03-1, BRD-K47936004-003-11-4, SR-01000076091-11, Z31240640, 1-(2-Pyrimidyl)-4-(3,4-methylenedioxybenzyl)piperazine, 2-{4-[(1,3-Benzodioxol-5-yl)methyl]piperazin-1-yl}pyrimidine, 2-{4-[(1,3-dioxaindan-5-yl)methyl]piperazin-1-yl}pyrimidine, 2-(4-(Benzo[d][1 pound not3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
Theoretical properties:
molecular_formula: C16H18N4O2
molecular_weight: 298.34 g/mol
exact_mass: 298.14297583 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 6
rotatable_bond_count: 3
heavy_atom_count: 22
topological_polar_surface_area: 50.7 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine is a N-arylpiperazine.
chembl: PIRIBEDIL is a small molecule listed in the ChEMBL database and has reached clinical trial phase 3.0.
wikipedia: Piribedil is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. It also has α2-adrenergic antagonist properties.