Compound: 2-(1,3,4-Oxadiazol-2-yl)phenol
SMILES: o1c(nnc1)-c2c(O)cccc2
InChIKey: OINXXHYENYVYPB-UHFFFAOYSA-N
Synonyms: 2-(1,3,4-Oxadiazol-2-yl)phenol, Fenadiazole, Fenadiazol, Hypnazol, Eudormil, Viodor, Fenadiazolum, JL 512, o-1,3,4-Oxadiazol-2-ylphenol, PHENOL, 2-(1,3,4-OXADIAZOL-2-YL)-, Phenol, o-1,3,4-oxadiazol-2-yl-, J. L. 512, Fenadiazole [INN:DCF], Fenadiazol [INN-Spanish], Fenadiazolum [INN-Latin], 2-(o-Hydroxyphenyl)-1,3,4-oxadiazole, NSC 100729, UNII-8YX6HIZ0IP, 8YX6HIZ0IP, 1,3,4-Oxadiazole, 2-(o-hydroxyphenyl)-, JL-512, NSC-100729, BRN 0136925, DTXSID7057608, FENADIAZOLE [MI], FENADIAZOLE [INN], DTXCID5031397, o-1,3,4-Oxodiazol-2-ylphenol, CHEBI:134791, 4-27-00-07344 (Beilstein Handbook Reference), 2-(1,3,4-Oxadiazol-2-yl)-phenol, Fenadiazol (INN-Spanish), Fenadiazolum (INN-Latin), RefChem:140089, Phenol, o-1,3,4-oxadiazol-2-yl-(8CI), 680-965-8, OINXXHYENYVYPB-UHFFFAOYSA-N, 1008-65-7, 2-(1,3,4-oxadiazol-2-yl)benzenol, MFCD00020713, MLS002703546, 2-(2-hydroxyphenyl)-1,3,4-oxadiazole, o-1,4-Oxadiazol-2-ylphenol, SCHEMBL555484, Phenol,3,4-oxadiazol-2-yl-, IFLab1_006238, IFLab2_000252, SCHEMBL8629170, CHEMBL1903897, Phenol,3,4-oxadiazol-2-yl)-, SCHEMBL21061962, 2-(1,4-Oxadiazol-2-yl)phenol, HMS1429L12, BAA00865, Tox21_113759, NSC100729, SBB041007, STK409833, 2-(o-Hydroxyphenyl)-1,4-oxadiazole, ortho-1,3,4-Oxadiazol-2-yl-phenol, AKOS000269733, EBC-332127, SDCCGMLS-0065586.P001, IDI1_019278, 1,4-Oxadiazole, 2-(o-hydroxyphenyl)-, NCGC00253631-01, SMR001570263, CAS-1008-65-7, DB-058510, HY-115139, CS-0034608, NS00126328, ST50107712, EN300-110858, 10A-002, AT-057/42646623, Q5442960, BRD-K18362446-001-06-8, Z57438332
Theoretical properties:
molecular_formula: C8H6N2O2
molecular_weight: 162.15 g/mol
exact_mass: 162.042927438 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 1
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 1
heavy_atom_count: 12
topological_polar_surface_area: 59.2 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: Fenadiazole is a biaryl that is phenol which is substituted at position 2 by a 1,3,4-oxadiazol-2-yl group. Formerly used as a hypnotic drug. It has a role as a sedative. It is a member of phenols, a member of 1,3,4-oxadiazoles and a biaryl.
chebi: A biaryl that is phenol which is substituted at position 2 by a 1,3,4-oxadiazol-2-yl group. Formerly used as a hypnotic drug.
chembl: FENADIAZOLE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Fenadiazole (INNTooltip International Nonproprietary Name), also known as phénadiazole (DCFTooltip Dénomination Commune Française) and sold under the brand names Hypnazol, Eudormil, and Viodor, is a hypnotic and sedative medication which has been used to treat insomnia but is no longer marketed. It is described as a non-barbiturate hypnotic with marked or profound hypnotic and sedative properties in animals, variable hypnotic effects in humans (rapidly inducing sleep for 6 to 8 hours), additional anticonvulsant, antithermal, and spasmolytic effects, and a generally well-tolerated profile in humans (at an average dosage of 200 mg/day). The drug was synthesized, pharmacologically characterized, patented, and marketed by the French pharmaceutical company Laboratoires Jacques Logeais between 1960 and 1962. As a hypnotic and sedative, fenadiazole has a unique oxadiazole-based chemical structure. It may be chemically related to certain other hypnotics and sedatives with atypical chemical structures. Fenadiazole was encountered online as a novel designer drug in 2025.