Compound: N-Acetylprocainamide
SMILES: O=C(NCCN(CC)CC)c1ccc(NC(=O)C)cc1
InChIKey: KEECCEWTUVWFCV-UHFFFAOYSA-N
Synonyms: N-Acetylprocainamide, Acecainide, 32795-44-1, Acecainida, Acekainid, Acecainidum, N-Acetyloprokainamid, Acetylprocainamide, N-acetylnovocainamide, N-Acetylprocaine amide, 4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide, n-acetyl-procainamide, Acetylprocainamide, n-, Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)-, CHEBI:60728, 910Q707V6F, DTXSID6048414, Acecainide Monohydrochloride, N-(4-((2-(diethylamino)ethyl)carbamoyl)phenyl)ethanimidic acid, N-(4-{[2-(diethylamino)ethyl]carbamoyl}phenyl)ethanimidic acid, N Acetylprocainamide, Hydrochloride, Acecainide, RefChem:108743, Monohydrochloride, Acecainide, DTXCID4028387, Acecainide [INN], 4-acetamido-N-[2-(diethylamino)ethyl]benzamide, N-[2-(diethylamino)ethyl]-4-acetamidobenzamide, Acecainide;NAPA, CHEMBL1097, MLS000069490, N-ACETYL PROCAINAMIDE(<30%), ACETANILIDE, 4'-((2-(DIETHYLAMINO)ETHYL)CARBAMOYL)-, SMR000059070, Acekainid [Polish], Acecainidum [INN-Latin], Acecainida [INN-Spanish], N-Acetyloprokainamid [Polish], BRN 2868559, N-(4-{N-[2-(diethylamino)ethyl]carbamoyl}phenyl)acetamide, UNII-910Q707V6F, MFCD00009052, Procainamide-N-acetyl, ACECAINIDE [MI], Opera_ID_1541, Spectrum3_001843, Lopac-A-5909, Epitope ID:140121, ACECAINIDE [WHO-DD], Lopac0_000009, BSPBio_003226, MLS001146871, SCHEMBL156943, N-Acetylprocainamide, >=99%, orb1310793, orb3141416, KBio3_002726, HMS2232G18, HMS3372E09, HBA79544, HY-B1109, BDBM50151860, EBC-03845, MSK174444, SBB005970, AKOS016614968, CCG-204105, CS-4707, SDCCGSBI-0049998.P003, NCGC00015072-01, NCGC00015072-02, NCGC00015072-03, NCGC00015072-04, NCGC00015072-05, NCGC00015072-06, NCGC00015072-07, NCGC00015072-13, NCGC00023226-03, NCGC00023226-04, AS-57414, ST057663, SBI-0049998.P002, DB-048268, N-Acetylprocainamide 1.0 mg/ml in Methanol, NS00008609, F85241, AB00384286_20, EN300-6492978, 4-Acetylamino-N-(2-diethylamino-ethyl)-benzamide, Q4726688, 4-(Acetylamino)-N-[2-(diethylamino)ethyl]benzamide #, BRD-K07753030-003-01-0, BRD-K07753030-003-11-9, BRD-K07753030-003-17-6, Z26393212
Theoretical properties:
molecular_formula: C15H23N3O2
molecular_weight: 277.36 g/mol
exact_mass: 277.17902698 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 7
heavy_atom_count: 20
topological_polar_surface_area: 61.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
Descriptions:
pubchem: N-acetylprocainamide is a benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine. It has a role as an anti-arrhythmia drug. It is a member of acetamides and a member of benzamides.
chebi: A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.
chembl: ACECAINIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Procainamide (PCA) is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias. It is a sodium channel blocker of cardiomyocytes; thus it is classified by the Vaughan Williams classification system as class Ia. In addition to blocking the INa current, it inhibits the IKr rectifier K+ current. Procainamide is also known to induce a voltage-dependent open channel block on the batrachotoxin (BTX)-activated sodium channels in cardiomyocytes.