Compound: strychnine
SMILES: O=C1N2c3c(cccc3)[C@@]45[C@@H]2[C@H]6[C@@H]7C(=CCO[C@H]6C1)CN([C@H]4C7)CC5
InChIKey: QMGVPVSNSZLJIA-FVWCLLPLSA-N
Synonyms: strychnine, Strychnidin-10-one, 57-24-9, (-)-Strychnine, Sanaseed, Certox, Mole death, Strychninum, Gopher bait, Gopher-gitter, Boomer-rid, Hare-Rid, Mouse-tox, Kwik-kil, Ro-Dex, RCRA waste number P108, Stricnina, Strychnos, Mouse-nots, H9Y79VD43J, Mouse-rid, DTXSID6023600, CHEBI:28973, Dolco mouse cereal, NSC-5365, EPA Pesticide Chemical Code 076901, Pied piper mouse seed, DTXCID503600, (4br,7as,8ar,13S,13ar,13bs)-5,6,7a,8,8a,11,13a,13b-octahydro-13H-13,14-ethano-7,9-methanooxepino(3,4-a)pyrrolo(2,3-d)carbazol-15-one, Strynchnos, (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one, NUX-VOMICA, (1R,11S,18S,20R,21R,22S)-12-oxa-8,17-diazaheptacyclo(15.5.2.0^(1,18).0^(2,7).0^(8,22).0^(11,21).0^(15,20))tetracosa-2,4,6,14-tetraen-9-one, (1R,11S,18S,20R,21R,22S)-12-oxa-8,17-diazaheptacyclo[15.5.2.0^{1,18}.0^{2,7}.0^{8,22}.0^{11,21}.0^{15,20}]tetracosa-2,4,6,14-tetraen-9-one, (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo(3,2,1-ij)oxepino(2,3,4-de)pyrrolo(2,3-h)quinolin-14-one, (4bR,7aS,8aR,13S,13aR,13bS)-5,6,7a,8,8a,11,13a,13b-octahydro-13H-13,14-ethano-7,9-methanooxepino[3,4-a]pyrrolo[2,3-d]carbazol-15-one, Nitrate, Strychnine, RefChem:6264, (4aR,5aS,8aR,13aS,15aS,15bR)-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo(3,2,1-ij)oxepino(2,3,4-de)pyrrolo(2,3-h)quinoline-14-one, 12-oxa-8,17-diazaheptacyclo(15.5.2.01,18.02,7.08,22.011,21.015,20)tetracosa-2,4,6,14-tetraen-9-one, 200-319-7, (4aR,4a1R,5aS,8aR,8a1S,15aS)-4a1,5,5a,7,8,8a1,15,15a-octahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14(4aH)-one, Estricnina, Strychinos, NSC 5365, [3H]strychnine, Strychnine [NF], (11S,18S,22S,1R,20R,21R)-12-oxa-8,17-diazaheptacyclo[15.5.2.0<1,18>.0<2,7>.0<8 ,22>.0<11,21>.0<15,20>]tetracosa-2,4,6,14-tetraen-9-one, Strychnin [German], Stricnina [Italian], Caswell No. 805, Strychnine [BSI:ISO], UNII-H9Y79VD43J, Vauquline, Strychnine CRS, HSDB 2001, NCGC00163241-01, SY9, (-)-Strychnin, EINECS 200-319-7, UN1692, STRYCHNINE [MI], STRYCHNINE [ISO], STRYCHNINE [HSDB], RCRA waste no. P108, STRYCHNINE [VANDF], STRYCHNINUM [HPUS], NCIStruc1_001823, NCIStruc2_000542, STRYCHNINE [WHO-DD], SCHEMBL93798, GTPL347, orb105446, (19S)-Strychnidin-10-one, CHEMBL227934, GTPL2360, MEGxp0_001768, SCHEMBL14029424, QMGVPVSNSZLJIA-FVWCLLPLSA-N, HMS2089C04, Tox21_112038, BDBM50225707, PDSP2_000441, SBB006463, AKOS015955688, AC-8050, CAS-57-24-9, NCGC00142530-02, NCGC00186632-01, NCGC00186632-02, NCGC00489075-01, ST057252, NS00009135, S0249, Strychnine, PESTANAL(R), analytical standard, C06522, AB01275436-01, Q194406, Strychnine, European Pharmacopoeia (EP) Reference Standard
Theoretical properties:
molecular_formula: C21H22N2O2
molecular_weight: 334.4 g/mol
exact_mass: 334.168127949 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 3
rotatable_bond_count: 0
heavy_atom_count: 25
topological_polar_surface_area: 32.8 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Brilliant, colorless cubes from chloroform-ether
color: Brilliant, colorless cubes from chloroform-ether
odor: Odorless
boiling_point: 518 °F at 5 mmHg (EPA, 1998)
melting_point: 514 to 554 °F (EPA, 1998)
density: 1.36 at 68 °F (EPA, 1998) - Denser than water; will sink
solubility: 0.02 % (NIOSH, 2024)
vapor_pressure: Low (NIOSH, 2024)
Descriptions:
pubchem: Strychnine is a monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position. It has a role as a rodenticide, an avicide, a neurotransmitter agent, a cholinergic antagonist and a glycine receptor antagonist. It is an organic heteroheptacyclic compound and a monoterpenoid indole alkaloid. It is a conjugate base of a strychnine(1+). It derives from a hydride of a strychnidine.
chebi: A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.
chembl: STRYCHNINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase -1.0.
wikipedia: Strychnine (, STRIK-neen, -⁠nin, US chiefly  -⁠nyne) is a highly toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, or absorbed through the eyes or mouth, causes poisoning which results in muscular convulsions and eventually death through asphyxia. While it is no longer used medicinally, it was used historically in small doses to strengthen muscle contractions, such as a heart and bowel stimulant and performance-enhancing drug. The most common source is from the seeds of the Strychnos nux-vomica tree.