Compound: thonzylamine
SMILES: O(c1ccc(CN(c2ncccn2)CCN(C)C)cc1)C
InChIKey: GULNIHOSWFYMRN-UHFFFAOYSA-N
Synonyms: thonzylamine, 91-85-0, Neohetramine, Tonzilamine, Tonzilamina, Thonzylaminum, Tonamil, 2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine, R79646H5Z8, N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2-pyrimidyl)ethylenediamine, DTXSID8043864, Pyrimidine, 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-, Pyrimidine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]-, N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine, N-(2-(dimethylamino)ethyl)-N-((4-methoxyphenyl)methyl)pyrimidin-2-amine, RefChem:189696, DTXCID6023864, D04AA01, R01AC06, R06AC06, 2-((2-(dimethylamino)ethyl)(4-methoxybenzyl)amino)pyrimidine, 202-103-8, N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine, NCI-C60708, N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine, Ethylenediamine, N-(p-methoxybenzyl)-N',N'-dimethyl-N-2-pyrimidinyl-, MFCD00865672, Thonzylamine (INN), THONZYLAMINE [INN], 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyrimidinyl-, Tonzilamina [DCIT], Toncilaminio, Thonzylamine [INN:BAN], Thonzylaminum [INN-Latin], 1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyrimidinyl-, Toncilaminio [INN-Spanish], N-(4-methoxybenzyl)-N-(2-(dimethylamino)ethyl)pyrimidin-2-amine, EINECS 202-103-8, BRN 0284655, UNII-R79646H5Z8, N1-[(4-Methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyrimidinyl-1,2-ethanediamine;, Tonamil (TN), Anahist (Salt/Mix), Anohist (Salt/Mix), Resistab (Salt/Mix), Spectrum_000411, Thonzylamine (Standard), Novohetramin (Salt/Mix), Spectrum3_001788, Spectrum4_001204, BSPBio_003315, KBioGR_001608, KBioSS_000891, 4-25-00-02087 (Beilstein Handbook Reference), DivK1c_000378, SCHEMBL121996, THONZYLAMINE [WHO-DD], orb1302755, CHEMBL1623738, HY-B1317R, KBio1_000378, KBio2_000891, KBio2_003459, KBio2_006027, KBio3_002817, CHEBI:104017, NINDS_000378, HMS5085H06, EX-A5550, HY-B1317, EBC-26454, s6469, AKOS016010333, DB11235, SB59763, IDI1_000378, NCGC00178145-01, DA-58538, TS-09031, SBI-0051778.P002, CS-0013078, NS00007410, D08587, F87601, AB00053649_02, EN300-18563897, Q617226, BRD-K88405679-003-01-5, BRD-K88405679-003-02-3, BRD-K88405679-003-03-1, 2-[p-Methoxybenzyl-(2-dimethylaminoethyl)amino]pyrimidine, pyrimidine, 2-((2-dimethylaminoethyl)-(4-methoxybenzyl)amino)-, N-(4-Methoxybenzyl)-N',N'-dimethyl-N-pyrimidin-2-ylethane-1,2-diamine, N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine, N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-yl-ethane-1,2-diamine, N-[(4-METHOXYPHENYL)METHYL]-N',N'-DIMETHYL-N-PYRIMIDIN-2-YLETHANE-1,2-DIAMINE HYDROCHLORIDE, N~1~-[(4-Methoxyphenyl)methyl]-N~2~,N~2~-dimethyl-N~1~-(pyrimidin-2-yl)ethane-1,2-diamine
Theoretical properties:
molecular_formula: C16H22N4O
molecular_weight: 286.37 g/mol
exact_mass: 286.17936134 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 5
rotatable_bond_count: 7
heavy_atom_count: 21
topological_polar_surface_area: 41.5 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
melting_point: 173-176
solubility: Highly Soluble
Descriptions:
pubchem: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes.
chembl: THONZYLAMINE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 2.0.
wikipedia: Thonzylamine (or neohetramine) is an antihistamine and anticholinergic used as an antipruritic.