Compound: felbamate
SMILES: O=C(OCC(c1ccccc1)COC(=O)N)N
InChIKey: WKGXYQFOCVYPAC-UHFFFAOYSA-N
Synonyms: felbamate, 25451-15-4, Felbatol, 2-Phenyl-1,3-propanediol dicarbamate, Taloxa, Felbamato, Felbamatum, W-554, 1,3-Propanediol, 2-phenyl-, dicarbamate, ADD-03055, W 554, carbamic acid 2-phenyltrimethylene ester, DTXSID9023041, Carbamic acid, 2-phenyltrimethylene ester, 3-(carbamoyloxy)-2-phenylpropyl carbamate, NSC-759866, CHEBI:4995, X72RBB02N8, ADD 03055, DTXCID903041, 4-06-00-05993 (Beilstein Handbook Reference), Carbamic acid 3-carbamoyloxy-2-phenyl-propyl ester, ADD03055, 2 Phenyl 1,3 propanediol dicarbamate, W554, RefChem:57692, N03AX10, 247-001-4, 2-Phenylpropane-1,3-diyl dicarbamate, Felbamyl, MFCD00865296, (3-carbamoyloxy-1,1,3,3-tetradeuterio-2-phenylpropyl) carbamate, MLS000028465, s1330, Felbamatum [Latin], NCGC00015429-08, W-554;ADD-03055, Felbamato [Spanish], SMR000058448, Felbamate [USAN:INN], (3-carbamoyloxy-2-phenylpropyl) carbamate, Felbatol (TN), CAS-25451-15-4, (3-carbamoyloxy-2-phenyl-propyl) carbamate, SR-01000000089, EINECS 247-001-4, BRN 3345236, UNII-X72RBB02N8, Felbamate?, HSDB 7525, Felbamate (Standard), Felbamate (USPINN), Tocris-0869, FELBAMATE [INN], FELBAMATE [MI], FELBAMATE [HSDB], FELBAMATE [USAN], 2-Phenyl-1,3-propanediol 1,3-dicarbamate, Opera_ID_1738, Prestwick0_000919, FELBAMATE [VANDF], GlyTouCan:G66398VH, Lopac-F-0778, Biomol-NT_000203, FELBAMATE [MART.], F 0778, FELBAMATE [USP-RS], FELBAMATE [WHO-DD], CHEMBL1094, Lopac0_000524, SCHEMBL34947, MLS001077299, BIDD:GT0463, BPBio1_001258, GTPL5473, orb1307014, FELBAMATE [ORANGE BOOK], HY-B0184R, EX-A591, FELBAMATE [USP MONOGRAPH], GLXC-06734, HMS2093P19, HMS2234H06, HMS3261J09, HMS3266L12, HMS3370I06, HMS3411P21, HMS3657I11, HMS3675P21, HMS3715D20, HMS3884E11, HMS5079H11, Pharmakon1600-01505600, G66398VH, HY-B0184, MSK11368, Tox21_110145, Tox21_302368, Tox21_500524, BDBM50088430, EBC-06581, NSC759866, AKOS015895100, Tox21_110145_1, AC-8197, CCG-204614, CS-2068, DB00949, KS-1171, LP00524, NSC 759866, SDCCGSBI-0050507.P003, NCGC00015429-01, NCGC00015429-02, NCGC00015429-03, NCGC00015429-04, NCGC00015429-05, NCGC00015429-06, NCGC00015429-07, NCGC00015429-09, NCGC00015429-10, NCGC00015429-11, NCGC00015429-14, NCGC00015429-24, NCGC00023092-02, NCGC00023092-04, NCGC00023092-05, NCGC00023092-06, NCGC00255275-01, NCGC00261209-01, SBI-0050507.P002, DB-046702, AE2 - Newer Anti-epileptic drug mixtures 2, EU-0100524, NS00010360, SW197633-2, C07501, D00536, EN300-119542, AB00382985-18, AB00382985_19, Q421301, SR-01000000089-2, SR-01000000089-4, SR-01000000089-7, BRD-K99107520-001-01-9, BRD-K99107520-001-09-2, BRD-K99107520-001-18-3, BRD-K99107520-001-23-3, BRD-K99107520-001-24-1, BRD-K99107520-001-25-8, Z1521554005, Felbamate, United States Pharmacopeia (USP) Reference Standard
Theoretical properties:
molecular_formula: C11H14N2O4
molecular_weight: 238.24 g/mol
exact_mass: 238.09535693 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 2
hydrogen_bond_acceptor_count: 4
rotatable_bond_count: 7
heavy_atom_count: 17
topological_polar_surface_area: 105 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: White powder
color: White powder
odor: Odorless
solubility: Slightly soluble in water
Descriptions:
pubchem: Felbamate is the bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy. It has a role as an anticonvulsant and a neuroprotective agent.
chebi: The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
chembl: FELBAMATE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Felbamate (marketed under the brand name Felbatol by MedPointe) is an anticonvulsant used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox–Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drug's usage to severe refractory epilepsy.