Compound: METHSUXIMIDE
SMILES: O=C1N(C(=O)CC1(c2ccccc2)C)C
InChIKey: AJXPJJZHWIXJCJ-UHFFFAOYSA-N
Synonyms: METHSUXIMIDE, Mesuximide, 77-41-8, Celontin, 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione, Methsuximid, Metsuccimide, Mesuximidum, mesuximid, alpha-Methylphensuximide, N,2-Dimethyl-2-phenylsuccinimide, 1,3-Dimethyl-3-phenylsuccinimide, Mesuximida, Metosuccimmide, 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine, 1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione, 2,5-Pyrrolidinedione, 1,3-dimethyl-3-phenyl-, N-Methyl-alpha-methyl-alpha-phenylsuccinimide, alpha-Methyl-alpha-phenyl N-methyl succinimide, PM 396, (RS)-1,3-Dimethyl-3-phenyl-2,5-pyrrolidindion, Succinimide, N,2-dimethyl-2-phenyl-, Methsuximide (USP), NSC-760075, Methsuximide [USP], DTXSID5023293, 0G76K8X6C0, DTXCID603293, RefChem:56654, N03AD03, 201-026-7, Petinutin, Metosuccimmide [DCIT], Mesuximidum [INN-Latin], 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione, Mesuximida [INN-Spanish], MFCD00072132, Mesuximide (INN), Mesuximide [INN], NCGC00189077-01, Celontin (TN), (+/-)-Mesuximide, HSDB 3124, EINECS 201-026-7, BRN 0168315, (+-)-N,2-Dimethyl-2-phenylsuccinimide, UNII-0G76K8X6C0, Mesuximide; Celontin, Methsuximide (Standard), METHSUXIMIDE [MI], .alpha.-Methylphensuximide, CHEMBL697, 1,3-Dimethyl-3-phenyl-pyrrolidine-2,5-dione, 2,5-Pyrrolidinedione,1,3-dimethyl-3-phenyl-, METHSUXIMIDE [HSDB], MESUXIMIDE [MART.], MESUXIMIDE [WHO-DD], METHSUXIMIDE [VANDF], SCHEMBL34852, 5-21-11-00209 (Beilstein Handbook Reference), METHSUXIMIDE [USP-RS], CHEBI:6846, GTPL7228, orb1705017, orb3141150, 2,5-Pyrrolidinedione,1,3-dimethyl-3-phenyl-, (+-)-, HY-B1376R, HMS3264P21, METHSUXIMIDE [ORANGE BOOK], Pharmakon1600-01505443, HY-B1376, METHSUXIMIDE [USP MONOGRAPH], Tox21_113613, AC9293, EBC-26193, MSK165599, NSC760075, AKOS015962173, CCG-213444, DB05246, NSC 760075, CAS-77-41-8, AC-15963, AS-88007, DA-65373, SY251111, CS-0013113, NS00008219, 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione #, D00404, SBI-0653356.0001, (+/-)-N,2-DIMETHYL-2-PHENYLSUCCINIMIDE, AB01563316_01, EN300-9537236, N-Methyl-.alpha.,.alpha.-methylphenylsuccinimide, ( inverted exclamation markA)-Mesuximide,PM 396, F600858, N-Methyl-.alpha.-methyl-.alpha.-phenylsuccinimide, Q906414, SR-01000942246, .alpha.-Methyl-.alpha.-phenyl N-methyl succinimide, SR-01000942246-1, BRD-A57592049-001-01-6, Z649373426, 2,5-PYRROLIDINEDIONE,1,3-DIMETHYL-3-PHENYL-, (+/-)-
Theoretical properties:
molecular_formula: C12H13NO2
molecular_weight: 203.24 g/mol
exact_mass: 203.094628657 g/mol
formal_charge: 0
hydrogen_bond_donor_count: 0
hydrogen_bond_acceptor_count: 2
rotatable_bond_count: 1
heavy_atom_count: 15
topological_polar_surface_area: 37.4 Å²
isotope_atom_count: 0
covalently_bonded_unit_count: 1
Physical properties:
physical_state: Crystals from dilute alcohol
color: Crystals from dilute alcohol
odor: Odorless to slight odor
solubility: Freely sol in methanol, alcohol
Descriptions:
pubchem: Methsuximide is an organic molecular entity.
chembl: METHSUXIMIDE is a small molecule listed in the ChEMBL database and has reached clinical trial phase 4.0.
wikipedia: Mesuximide (or methsuximide, methosuximide) is a succinimide anticonvulsant medication. It is sold as a racemate by Pfizer under the tradenames Petinutin (Switzerland) and Celontin (United States). The therapeutic efficacy of methosuximide is largely due to its pharmacologically active metabolite, N-desmethylmethosuximide, which has a longer half-life and attains much higher plasma levels than its parent.