Premise: Opal Koboi is a fictional character from the Artemis Fowl series by Eoin Colfer. After the character's introduction in in the series as a supporting antagonist, Colfer again used Koboi as the main antagonist of the fourth, sixth, and eighth books in the series, giving her the status of archenemy to Artemis Fowl II.
Hypothesis: Artemis Fowl II is Opal's archenemy.