Premise: The Nativity Story is a 2006 biblical drama film based on the nativity of Jesus, directed by Catherine Hardwicke and starring Keisha Castle-Hughes and Oscar Isaac. The film was released on December 1, 2006 after it premiered in Vatican City November 27, 2006. "The Nativity Story" was the first film to hold its world premiere in Vatican City.
Hypothesis: If you leave me now was the first film to hold it's world premiere in Vatican City.