Premise: Splice is a 2009 Canadian-French science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac. The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes. Guillermo del Toro, Don Murphy, and Joel Silver executive produced.
Hypothesis: splice is a comedy film direced by guillermo del toro