Premise: The Lady Vanishes is a 1979 English comedy mystery film directed by Anthony Page. Its screenplay by George Axelrod was based on the novel "The Wheel Spins" by Ethel Lina White (1876–1944). It stars Elliott Gould as Robert, Cybill Shepherd as Amanda (Iris), Angela Lansbury as Miss Froy, Herbert Lom, Arthur Lowe and Ian Carmichael as Charters and Caldicott.
Hypothesis: George Axelrod was very familiar with the Novel The Wheel Spins.