Can Hemlibra be used in people who don’t have inhibitors?
Yes. Hemlibra is FDA-approved for use in people with hemophilia A who don’t have inhibitors (as well as people who do). Clinical studies compared Hemlibra to no treatment. They looked at two groups of people without inhibitors: male children ages 12 and older, and male adults. The two groups took the medication for at least 24 weeks and had:
95 percent fewer bleeds when taking 1.5 mg/kg of Hemlibra every week
94 percent fewer bleeds when taking 3 mg/kg of Hemlibra every two weeks
The effectiveness of Hemlibra in the studies was similar between people with inhibitors and without inhibitors.