My plan was not to hang them square but diamond style.
However, that was not possible because they wouldn't lay straight on the wall.  So I then changed to square and they were fine.  I have them going up the wall to the upstairs.  A little challenging to do, but it really does look nice against a Benjamin Moore citrine colored wall.  I did two spaced out and then a scrollwork basket from Pier 1 and then two more spaced out.  Looks great! Years ago I had the family photos - so difficult to space out - then I did a stenciled mural for 10 years, now I'm doing this!  Gotta change it up!