I waited 48 hours after setting it up before I slept in it. OMG! Last night was the best sleep I’ve had in a Long time. I woke up this afternoon just in time for appointment!! I slept about 14 hours! Was away from home about an hour. Sat down on bed and woke up about an hour ago! I can tell a big difference in the way my body feels! I will be recommending this to Mattress to everyone I see.