Set up was pretty easy, with just needing to take the tape off the sides of the machine as well as the plastic off the inside with the filter.  I find that the buttons are a little difficult to see (they blend in a little too well).  
I have been searching for a machine to help with allergies related to dust mites and the past couple days my allergies have been a bit better after running the air purifier.  I will continue to monitor this change over time to see if it will continue to improve.