SEQ ID NO. Séquence polypeptidique Objet 1 FTSEISN CDR1 de H4 2 GTHTTQT CDR2 de H4 3 AEQDMSDLWLGS CDR3 de H4 4 YGWWIYE CDR1 de H10 5 WADGTRT CDR2 de H10 6 IYILEGTQGVPI CDR3 de H10 7 NIFSSNT CDR1 de I5 8 ISKGGSTN CDR2 de I5 9 NPVPDSDNYASGQG CDR3 de I5 10 SIFSSNV CDR1 de I7 11 ISRGGGTN CDR2 de I7 12 PIPYSGDYVSGQG CDR3 de I7 13 STFSMNV CDR1 de I3 14 IGTGGGTN CDR2 de I3 15 NKIPHNWGWGQG CDR3 de I3 16 MAEVQLQASGGGFVQPGGSLRLSCAASG FTSEISN MGWFRQAPGKEREFVSAIS GTHTTQT YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA AEQDMSDLWLGS YWGQGTQVTVSS H4 17 MAEVQLQASGGGFVQPGGSLRLSCAASG YGWWIYE MGWFRQAPGKEREFVSAIS WADGTRT YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA IYILEGTQGVPI YWGQGTQVTVSS H10 18 MAQVQLVESGGGLVQPGGFLRLLCTASG NIFSSNT MGWYRRAPGKQREWVAS ISKGGSTN YADSVKDRFTISRSITKNTVYLQMVNLKPEDTAVYYC NPVPDSDNYASGQG TQVTVSS I5 19 MAQVQLVESGGGLVPPGGSLKLSCTASG SIFSSN VMGWYRRAPGKQREWVAS ISRGGGTN YPDSVKGRFTVSRDIAKNTVYLQISSLKPEDTAVYYCN PIPYSGDYVSGQG TQVTVSS I7 20 MAQVQLVESGGGLVEPGGSLRLSCAVSG STFSMNV MGWYRQAPGKHREWVGS IGTGGGTN YPDSVKGRFTISRDNVKKTVYLQMNSLKPEDTAVYYC NKIPHNWGWGQG TQVTVSS I3 21 MAEVQLQASGGGFVQPGGSLRLSCAASG FTSEISN MGWFRQAPGKEREFVSAIS GTHTTQT YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA AEQDMSDLWLGS YWGQGTQVTVSSAAAGSGSGSGSGSGSGGSQVQLVESGGGLVQPGGFLRLLCTASG NIFSSNT MGWYRRAPGKQREWVAS ISKGGSTN YADSVKDRFTISRSITKNTVYLQMVNLKPEDTAVYYCNPVP DSDNYAS GQGTQVTVSS D1 = H4 + I5 22 MAEVQLQASGGGFVQPGGSLRLSCAASG RTWSFYA MGWFRQAPGKEREFVSAIS WNGGGEH YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA HMEFSQSDYIISKWI YWGQGTQVTVSS H1 23 MAEVQLQASGGGFVQPGGSLRLSCAASG STSRDEG MGWFRQAPGKEREFVSAIS RDHGWRE YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA PVIIDTMEVIPL YWGQGTQVTVSS H2 24 MAEVQLQASGGGFVQPGGSLRLSCAASG ATYWFSS MGWFRQAPGKEREFVSAIS YWFDDIE YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA MWNEQTGEE YWGQGTQVTVSS H3 25 MAEVQLQASGGGFVQPGGSLRLSCAASG GTSFAYD MGWFRQAPGKEREFVSAIS RSNSDIN YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA EAIFWGHEVIPL YWGQGTQVTVSS H5 26 MAEVQLQASGGGFVQPGGSLRLSCAASG FTSARYN MGWFRQAPGKEREFVSAIS RHTDRQT YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA VGMMPKQKQ YWGQGTQVTVSS H6 27 MAEVQLQASGGGFVQPGGSLRLSCAASG YYFRGED MGWFRQAPGKEREFVSAIS DDSTATI YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA PGWYIYLDWSESGSA YWGQGTQVTVSS H7 28 MAEVQLQASGGGFVQPGGSLRLSCAASG YTSDLTV MGWFRQAPGKEREFVSAIS SHFGPPH YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA MRERRHSWW YWGQGTQVTVSS H8 29 MAEVQLQASGGGFVQPGGSLRLSCAASG DTFNLTT MGWFRQAPGKEREFVSAIS SSNTHIA YYADSVKGRFTISRDNSKNTVYLQMNSLRAEDTATYYCA YTYYGKNGKGMV YWGQGTQVTVSS H9 30 MAQVQLVESGGGLVQAGESLKLSCRMSG STSSIQA MGWYRQTPGKQREWVAS ISKGGSTN YADSVKDRFTISRSITKNTVYLQMVNLKPEDTAVYYC NPVPDSDNYASGQG TQVTVSS I1 31 MAQVQLVESGGGLVQPGGSLRLSCTASG SIFSSNV MGWYRRAPGKQREWVAS ISRGGGTN YPDSVKGRFTVSRDIAKNTVYLQISSLKPEDTAVYYC NPIPYSGDYVSGQG TQVTVSS I6 32 MADVQLVESGGGLVQAGGSLRLSCAVSG STFSMNV MGWYRQAPGKHREWVGS IGTGGGTN YPDSVKGRFTISRDNVKKTVYLQMNSLKPEDTAVYYC NKIPHNWGWGQG TQVTVSS I8 33 MMAQVQLVESGGGSVAAGESLTLSCRMSG STSSIQA MGWYRRAPGNQREWLAT ISPRGNTN YADSVKGRFTISRDNAKNTVYLQMNSLKPADTAVYYC NTVPSGGIPWGQG TQVTVSS I4 34 MADVQLVESGGGSVPPGGSLRLSCAASG SIFTINS MGWFRQAPGNQREWLAT ISPRGNTN YADSVKGRFTISRDNAKNTVYLQMNSLKPADTAVYYC NTVPSGGIPWGQG TQVTVSS I9 35 MAQVQLVESGGGWVQPGGSLRLSCAASG ITFSTKT MGWYRQRPGKRREWIGS ISPTGFTN YADAVKGRVTISRDNGENTVYLQMNSLKPEDTAVYFC NGVPPVIIDGQSVAYWGQG TQVTVSS I2 36 MAQVQLVESGGGLVQPGGSLTLSCVISG TIFNDGSSVNA MNWYREAPGKGRVLIAS LDSAGITK YADSVNGRFTISADNARETVTLQMNNLAPEDTAVYYC AATKVWNSWYATYGIDYWGKG TQVTVSS I10 37 MAQVQLVESGGGTVQAGGSLRLSCTASG RGRNA MGWYRQVPGGKRELVAS INRGGTTD YTDSVKDRFTISRDSAKNTVYLQMDSLQPEDTAVYYC NAESTVIPGHIYDYWGRG TQVTVSS I11