Utilize the input text as a context reference, choose the right relationship between Unibanco and bank from the options. Options: product/material produced, manufacturer, distributed by, industry, position held, original broadcaster, owned by, founded by, distribution format, headquarters location, stock exchange, currency, parent organization, chief executive officer, director/manager, owner of, operator, member of, employer, chairperson, platform, subsidiary, legal form, publisher, developer, brand, business division, location of formation, creator.

With US$493.78 billion in assets as of June 30, Banco do Brasil SA, is the region's largest bank by almost US$100 billion, followed by Itaú Unibanco Holding SA with US$396.12 billion in assets.

Answer: product_or_material_produced