What is the relationship between Twitter and San Francisco in the context of the input sentence. Choose an answer from: product/material produced; manufacturer; distributed by; industry; position held; original broadcaster; owned by; founded by; distribution format; headquarters location; stock exchange; currency; parent organization; chief executive officer; director/manager; owner of; operator; member of; employer; chairperson; platform; subsidiary; legal form; publisher; developer; brand; business division; location of formation; creator.

Twitter Layoffs Reverberate in San Francisco -- Tech Roundup Written by: Steve Zuckerman 10/13/15 - 6:20 PM EDT Tickers in this article: TWTR FB INTC

Answer: headquarters_location