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SAN DIEGO--(BUSINESS WIRE)--Acadia Pharmaceuticals Inc. (Nasdaq: ACAD), a biopharmaceutical company focused on the development and commercialization of innovative medicines to address unmet medical needs in central nervous system disorders, today announced its financial results for the third quarter ended September 30, 2020. This quarter we drove strong performance through the continued growth of new prescribers with more patients benefitting from NUPLAZID treatment for their Parkinsons disease psychosis and remain on-track with our supplemental NDA for the treatment of dementia-related psychosis with a PDUFA date of April 3, 2021, said Steve Davis, Acadias Chief Executive Officer. We continue to advance our late-stage programs and invest in new opportunities through business development, highlighted by our recent acquisition of CerSci Therapeutics which expands our clinical pipeline with an innovative first-in-class, non-opioid, acute and chronic pain program. Company Updates Financial Results Revenue Net sales of NUPLAZID (pimavanserin) were $120.6 million for the three months ended September 30, 2020, an increase of 27% as compared to $94.6 million reported for the three months ended September 30, 2019. For the nine months ended September 30, 2020 and 2019, Acadia reported net product sales of $320.7 million and $240.8 million, respectively. Research and Development Research and development expenses for the three months ended September 30, 2020 were $120.1 million, compared to $62.6 million for the same period of 2019. This increase was primarily due to $52.8 million in upfront consideration and transaction expenses related to the acquisition of CerSci Therapeutics. For the nine months ended September 30, 2020 and 2019, research and development expenses were $257.0 million and $182.9 million, respectively. This increase was primarily due to the acquisition of CerSci Therapeutics and the upfront payment to Vanderbilt University for the M1 PAM program. Selling, General and Administrative Selling, general and administrative expenses for the three months ended September 30, 2020 were $81.6 million, compared to $72.7 million for the same period of 2019. For the nine months ended September 30, 2020 and 2019, selling, general and administrative expenses were $267.9 million and $233.8 million, respectively. This increase was primarily due to increased advertising and promotional costs as well as an increase in personnel and related costs. Net Loss For the three months ended September 30, 2020, Acadia reported a net loss of $84.7 million, or $0.54 per common share, compared to a net loss of $42.0 million, or $0.29 per common share, for the same period in 2019. The net losses for the three months ended September 30, 2020 and 2019 included $21.4 million and $22.0 million, respectively, of non-cash stock-based compensation expense. For the nine months ended September 30, 2020, Acadia reported a net loss of $214.8 million, or $1.37 per common share, compared to a net loss of $182.2 million, or $1.26 per common share, for the same period in 2019. The net losses for the nine months ended September 30, 2020 and 2019 included $63.2 million and $62.5 million, respectively, of non-cash stock-based compensation expense. Cash and Investments At September 30, 2020, Acadias cash, cash equivalents, and investment securities totaled $644.4 million, compared to $697.4 million at December 31, 2019. 2020 Financial Guidance Conference Call and Webcast Information Acadia management will review its third quarter financial results and operations via conference call and webcast today at 4:30 p.m. Eastern Time. The conference call may be accessed by dialing 855-638-4820 for participants in the United States or Canada and 443-877-4067 for international callers (reference passcode 6266016). A telephone replay of the conference call may be accessed through November 18, 2020 by dialing 855-859-2056 for callers in the United States or Canada and 404-537-3406 for international callers (reference passcode 6266016). The conference call also will be webcast live on Acadias website, www.acadia-pharm.com, under the investors section and will be archived there until December 2, 2020. About NUPLAZID (pimavanserin) NUPLAZID is the first and only FDA-approved treatment for hallucinations and delusions associated with Parkinsons disease psychosis. NUPLAZID is a selective serotonin inverse agonist/antagonist preferentially targeting 5-HT2A receptors that are thought to play an important role in Parkinsons disease psychosis. NUPLAZID is an oral medicine taken once a day with a recommended dose of 34 mg. NUPLAZID is not FDA-approved for any other neuropsychiatric disorders. Acadia discovered and developed this new chemical entity and holds worldwide rights to develop and commercialize NUPLAZID. About Trofinetide Trofinetide is an investigational drug. It is a novel synthetic analog of the amino-terminal tripeptide of IGF-1 designed to treat the core symptoms of Rett syndrome by potentially reducing neuroinflammation and supporting synaptic function. In the central nervous system, IGF-1 is produced by both of the major types of brain cells neurons and glia. IGF-1 in the brain is critical for both normal development and for response to injury and disease. Trofinetide has been granted Fast Track Status and Orphan Drug Designation in the U.S. and Orphan Drug Designation in Europe for both Rett syndrome and Fragile X syndrome. About Acadia Pharmaceuticals Acadia is trailblazing breakthroughs in neuroscience to elevate life through science. For more than 25 years we have been working at the forefront of healthcare to bring vital solutions to people who need them most. We developed and commercialized the first and only approved therapy for hallucinations and delusions associated with Parkinsons disease psychosis. Our late-stage development efforts are focused on dementia-related psychosis, negative symptoms of schizophrenia and Rett syndrome, and in early-stage clinical research we are exploring novel approaches to pain management, cognition and neuropsychiatric symptoms in central nervous system disorders. For more information, visit us at www.acadia-pharm.com and follow us on LinkedIn. Forward-Looking Statements Statements in this press release that are not strictly historical in nature are forward-looking statements. These statements include, but are not limited to, statements related to: the potential opportunity for future growth in sales of NUPLAZID; the timing of ongoing and future clinical studies for pimavanserin; the development and commercialization of trofinetide, ACP-044 and the M1 PAM program; unanticipated impacts of COVID-19 on Acadias business, including its commercial sales operations, current and planned clinical trials, supply chain, and guidance for full-year 2020 NUPLAZID net sales and certain expense line items. These statements are only predictions based on current information and expectations and involve a number of risks and uncertainties. Actual events or results may differ materially from those projected in any of such statements due to various factors, including the uncertainty of future commercial sales and related items that would impact net sales during 2020, the risks and uncertainties inherent in drug development, approval and commercialization, and the fact that past results of clinical trials may not be indicative of future trial results. For a discussion of these and other factors, please refer to Acadias annual report on Form 10-K for the year ended December 31, 2019 as well as Acadias subsequent filings with the Securities and Exchange Commission. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. This caution is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. All forward-looking statements are qualified in their entirety by this cautionary statement and Acadia undertakes no obligation to revise or update this press release to reflect events or circumstances after the date hereof, except as required by law. Copyright 2020 by Tiburon Sunrise, LLC ACADIA PHARMACEUTICALS INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (in thousands, except per share amounts) (Unaudited) Three Months Ended September 30, Nine Months Ended September 30, 2020 2019 2020 2019 Revenues Product sales, net $ 120,577 $ 94,586 $ 320,748 $ 240,750 Total revenues 120,577 94,586 320,748 240,750 Operating expenses Cost of product sales, license fees and royalties (1) 4,801 4,689 15,249 14,264 Research and development (1) 120,083 62,622 257,014 182,865 Selling, general and administrative (1) 81,592 72,696 267,909 233,767 Total operating expenses 206,476 140,007 540,172 430,896 Loss from operations (85,899 ) (45,421 ) (219,424 ) (190,146 ) Interest income, net 1,242 2,432 6,056 7,893 Other (expense) income (202 ) 747 (1,262 ) 506 Loss before income taxes (84,859 ) (42,242 ) (214,630 ) (181,747 ) Income tax expense (199 ) (264 ) 194 476 Net loss $ (84,660 ) $ (41,978 ) $ (214,824 ) $ (182,223 ) Net loss per common share, basic and diluted $ (0.54 ) $ (0.29 ) $ (1.37 ) $ (1.26 ) Weighted average common shares outstanding, basic and diluted 158,129 145,906 156,683 144,741 (1) Includes the following stock-based compensation expense Cost of product sales, license fees and royalties $ 495 $ 372 $ 2,087 $ 2,344 Research and development $ 7,953 $ 8,680 $ 23,645 $ 24,461 Selling, general and administrative $ 12,924 $ 12,971 $ 37,495 $ 35,697 ACADIA PHARMACEUTICALS INC. CONDENSED CONSOLIDATED BALANCE SHEETS (in thousands) September 30, 2020 December 31, 2019 (unaudited) Assets Cash, cash equivalents and investment securities $ 644,441 $ 697,429 Accounts receivable, net 46,344 35,781 Interest and other receivables 1,440 2,093 Inventory 7,979 6,341 Prepaid expenses 30,009 18,606 Total current assets 730,213 760,250 Property and equipment, net 8,427 3,180 Operating lease right-of-use assets 48,232 9,524 Intangible assets, net 1,477 2,585 Restricted cash 5,770 4,787 Other assets 1,545 2,857 Total assets $ 795,664 $ 783,183 Liabilities and stockholders equity Accounts payable $ 3,471 $ 7,222 Accrued liabilities 88,385 67,604 Total current liabilities 91,856 74,826 Operating lease liabilities 45,343 6,361 Other long-term liabilities 3,598 2,861 Total liabilities 140,797 84,048 Total stockholders equity 654,867 699,135 Total liabilities and stockholders equity $ 795,664 $ 783,183

Answer: Acadia Pharmaceuticals Reports Third Quarter 2020 Financial Results - 3Q20 Net Sales of $120.6 Million, a 27% Increase Over 3Q19