IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COC1(C)OC(C)(C)C2CC(=O)C3(C)C(C(O)CC4(C)C(c5ccoc5)OC(=O)C5OC543)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1R,2R,4S,7S,8S,10S,11R,12R,13S,16R)-7-(furan-3-yl)-10-hydroxy-13-methoxy-1,8,12,13,15,15-hexamethyl-3,6,14-trioxapentacyclo[9.7.0.02,4.02,8.012,16]octadecane-5,18-dione is a natural product found in Clausena excavata with data available.
Molecule SMILES: COC(C=CC=CC=CC=CC=CC(C)C(O)C(C)C1OC2(CC(OC)C(C)C(C(C)C(O)C(C)CC(C)=CCO)O2)C(O)CC1C)CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Spirangien G is a natural product found in Sorangium cellulosum with data available.
Molecule SMILES: CC(=O)OC1COC(Oc2c(O)cc(O)c3c(=O)c(O)c(-c4ccc(O)cc4)oc23)C(OC(C)=O)C1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Herbacetin 8-(2'',3'',4''-triacetylxyloside) is a member of flavonoids and a glycoside.
Molecule SMILES: CCC(C)C(NC(=O)C(CO)NC(=O)C(NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(N)CC(N)=O)C(C)C)C(=O)N1CCCC1C(=O)NC(CCC(N)=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Davunetide has been used in trials studying the treatment of Progressive Nonfluent Aphasia, Progressive Supranuclear Palsy, Predicted Tauopathies, Including, Corticobasal Degeneration Syndrome, and Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17.  Davunetide is the first drug to improve memory performance by impacting the mechanisms that lead to physical damage in the brain caused by neurofibrillary tangles, one of the two established pathological hallmarks that are common to amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD). Davunetide is derived from a naturally occurring neuroprotective brain protein known as activity dependent neuroprotective protein.
Molecule SMILES: CN(C)C(=O)c1ccc(-c2ccc(C3C4CN(C(=O)c5ccccn5)CC3N4)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N,N-dimethyl-4-[4-[(1R,5S)-3-[oxo(2-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]heptan-7-yl]phenyl]benzamide is a member of piperidines.
Molecule SMILES: [NH3+]C(CSCC(=O)[O-])C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: S-Carboxymethyl-D-cysteine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: CC(Oc1ccc(Oc2nc3ccc(Cl)cc3o2)cc1)C(=O)N(C)c1ccccc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}-N-(2-fluorophenyl)-N-methylpropanamide is a member of the class of 1,3-benzoxazoles that is 6-chloro-1,3-benzoxazol-2-ol in which the hydrogen of the hydroxy group at position 2 is substituted by a 4-({1-[(2-fluorophenyl)(methyl)amino]-1-oxopropan-2-yl}oxy)phenyl group. It is a member of 1,3-benzoxazoles, an organochlorine compound, an aromatic ether, a member of monofluorobenzenes and a tertiary carboxamide.
Molecule SMILES: C=C1C(=O)OC2C1CCC(=C)C1CC(OC(=O)C(C)CC)C(=C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: [(3aS,6aR,8S,9aR,9bS)-3,6,9-trimethylidene-2-oxo-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-8-yl] (2R)-2-methylbutanoate is a natural product found in Fitchia speciosa with data available.
Molecule SMILES: Nc1ccc2nc(CCCO)[nH]c2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-(6-amino-1H-benzimidazol-2-yl)-1-propanol is a member of benzimidazoles.
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(OC5OC(CO)C(O)C(OC6(C(=O)O)CC(O)C(NC(=O)CO)C(C(O)C(O)CO)O6)C5O)C(O)C4NC(C)=O)C3O)C(O)C2NC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2S,4S,5R,6R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-5-Acetamido-6-[(2R,3S,4S,5S,6R)-2-[(2S,3S,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-5-acetamido-6-[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-[[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-4-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-5-[(2-hydroxyacetyl)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.
Molecule SMILES: COc1cc(OC)c2c(c1OC)CN(C)c1c-2ccc2cc3c(cc12)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 1,2,4-Trimethoxy-12,13-dihydro-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridine is a natural product found in Chelidonium majus with data available.
Molecule SMILES: COC(=O)C12CCC(C)(C)CC1C13C=CC4C5(C)CC(OC(C)=O)C(OC(C)=O)C(C)(COC(C)=O)C5CCC4(C)C1(CC2)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: methyl (1R,2R,5R,6S,7S,8R,10S,11R,14S,15S,20S)-7,8-diacetyloxy-6-(acetyloxymethyl)-2,6,10,17,17-pentamethylhexacyclo[12.8.1.01,14.02,11.05,10.015,20]tricos-12-ene-20-carboxylate is a natural product found in Prunella vulgaris with data available.
Molecule SMILES: CC(C)=CCC=C(C)c1cc(O)c(C)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2-methyl-5-[(2E)-6-methylhepta-2,5-dien-2-yl]benzene-1,4-diol is a natural product found in Halichondria with data available.
Molecule SMILES: CC(=CCCC1(C)C=Cc2c(O)cc(C)cc2O1)CC=CC(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Daurichromene C is a natural product found in Rhododendron dauricum with data available.
Molecule SMILES: CC(C=CC=C(C)C=Cc1c(C)cc(O)c(C)c1C)=CC=CC=C(C)C=CC=C(C)C=Cc1c(C)cc(O)c(C)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3,3'-Dihydroxyisorenieratene is a natural product found in Brevibacterium linens, Streptomyces argillaceus, and other organisms with data available.
Molecule SMILES: C=C1CCC=C(C(=O)O)CCC2C1CC2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 11,11-Dimethyl-8-methylidenebicyclo[7.2.0]undec-4-ene-4-carboxylic acid is a natural product found in Lychnophora pinaster and Lychnophora ericoides with data available.
Molecule SMILES: CC(C)=CCc1cc(CCCc2ccc(O)cc2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Broussonin C is a member of phenols.
Molecule SMILES: CC(C)=CCc1cc(CCCc2ccc(O)cc2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Broussonin C is a natural product found in Broussonetia papyrifera with data available.
Molecule SMILES: CCCCC(O)C=CC(=O)OC1C(C)OC2(C)C(O)C(C)C(=O)OC2C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Botcinin E is a natural product found in Botrytis cinerea with data available.
Molecule SMILES: O=C(CCC(O)Cc1ccc(O)c(O)c1)OC1OC(C(=O)O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 6-{[5-(3,4-dihydroxyphenyl)-4-hydroxypentanoyl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid is a glucosiduronic acid.
Molecule SMILES: C=C(C)C1Oc2cc(O)c(C(C)=O)cc2C1OC(=O)C(C)=CC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (E)-2-Methyl-2-butenoic acid [(2R)-2alpha-isopropenyl-5-acetyl-6-hydroxy-2,3-dihydrobenzofuran]-3alpha-yl ester is a natural product found in Eutrochium purpureum var. purpureum with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(OC4OC(COC5OC(CO)C(O)C(O)C5O)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)C3O)C(O)C2NC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[(3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-Acetamido-5-[(2S,3S,4S,5R,6R)-4-[(2R,3S,4S,5S,6R)-3-[(2R,3S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-[[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,5-dihydroxy-6-[[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide is an amino sugar.
Molecule SMILES: COc1cc2c(cc1OC)-c1c(O)c(OC)c(OC)c3c1C(C2)N(C)CC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2,3,9,10-Tetramethoxy-6-methyl-5,6,6abeta,7-tetrahydro-4H-dibenzo[de,g]quinoline-1-ol is a natural product found in Thalictrum simplex with data available.
Molecule SMILES: CC1=CC=C2C=C(C(C)C)C(=O)C3(O)C2=C(CCC3(C)C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (5S)-5-hydroxy-6,6,11-trimethyl-3-propan-2-yltricyclo[7.4.1.05,14]tetradeca-1(13),2,9(14),11-tetraen-4-one is a natural product found in Salvia candidissima and Salvia prionitis with data available.
Molecule SMILES: CC(C)=CCCC(C)=CCc1c(O)cc(O)c2c1OC(c1c(O)cc(O)cc1O)CC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Sophoraflavanone E is a natural product found in Sophora tonkinensis with data available.
Molecule SMILES: COCC1C(=O)OC2C1C(OC(C)=O)CC(C)=CCC(OC(C)=O)C(C)=CCC(OC(C)=O)C1(C)OC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Michaolide H is a cembrane diterpenoid with cytotoxic activity isolated from the soft coral Lobophytum michaelae. It has a role as an antineoplastic agent and a coral metabolite. It is a gamma-lactone, an acetate ester, an epoxide, a macrocycle and a cembrane diterpenoid.
Molecule SMILES: CCN(CC)c1ccc(C=NNC(=O)OC)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[[4-(diethylamino)-6-oxo-1-cyclohexa-2,4-dienylidene]methylamino]carbamic acid methyl ester is a member of quinomethanes.
Molecule SMILES: COc1cccc(S(=O)(=O)NC2CCC(CCN)OC2CO)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N-[(2S,3S,6R)-6-(2-aminoethyl)-2-(hydroxymethyl)-3-oxanyl]-3-methoxybenzenesulfonamide is a C-glycosyl compound.
Molecule SMILES: CC1(C)CCCC2(C)C1CCC1(C)C2CC(O)C2(C)C3=C(CCC12)COC3=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Scalarolide is a natural product found in Cacospongia and Hyrtios erectus with data available.
Molecule SMILES: C=C1CCC2C3C(C(C)C)=CC(O)C3(C)CCC2(C)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Cyanthiwigin L is a natural product found in Myrmekioderma rea with data available.
Molecule SMILES: CC(=O)OC1CC2(O)C(OC(C)=O)C3C4(CO4)C(OC(C)=O)CC(OC(C)=O)C3(C)C(OC(C)=O)C(OC(C)=O)C(=C1C)C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1'R,2S,2'R,3'S,5'R,7'R,8'R,9'S,10'S,13'R)-2',5',9',10',13'-pentaacetyloxy-1'-hydroxy-8',12',15',15'-tetramethylspiro[oxirane-2,4'-tricyclo[9.3.1.03,8]pentadec-11-ene]-7'-yl] acetate is a natural product found in Taxus wallichiana with data available.
Molecule SMILES: CCOC(=O)c1nn(-c2ccccc2C)c(=O)c2c(N)scc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 5-amino-3-(2-methylphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester is an organonitrogen heterocyclic compound and an organosulfur heterocyclic compound.
Molecule SMILES: NCc1cc(COc2ccc(CCNC(=O)CCC(N)C(=O)O)cc2)co1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine is a L-glutamine derivative obtained by formal condensation of the side-chain carboxy group of L-glutamine with one of the amino groups of 2-(4-{[5-(aminomethyl)furan-3-yl]methoxy}phenyl)ethan-1-amine. It has a role as a bacterial metabolite. It is a L-glutamine derivative, a member of furans, a primary amino compound and an aromatic ether.
Molecule SMILES: CC1CN(C(C)CO)C(=O)c2cc(N(C)C)ccc2OC1CN(C)Cc1ccc(Oc2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (2R,3S)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one is an aromatic ether.
Molecule SMILES: NCC(Cl)C(O)c1cnc(N)[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Girolline is a natural product found in Cymbastela cantharella with data available.
Molecule SMILES: COC(=O)C(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Methyl-2-hydoxyisobutyric acid is a tertiary alcohol.
Molecule SMILES: C=C(CCC(C)C1CCC2(C(=O)O)C3=C(CCC12C)C1(C)CCC(OC2OCC(O)C(OC4OCC(OC5OC(CO)C(OC6OC(CO)C(O)C(O)C6OC6OCC(O)C(O)C6O)C(O)C5O)C(O)C4O)C2OC2OC(CO)C(O)C(O)C2O)C(C)(C)C1CC3)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Eryloside P is a natural product found in Erylus formosus with data available.
Molecule SMILES: COC(=O)C1=CCC2CCC1N2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Anhydroecgonine methyl ester is a N-alkylpyrrolidine.
Molecule SMILES: COC(=O)C1=CCC2CCC1N2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Methylecgonidine is a natural product found in Erythroxylum australe, Erythroxylum argentinum, and other organisms with data available.
Molecule SMILES: C=C(C)CCCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3C(O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2R,3S,4S,5R,6S)-2-[[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[(2R)-6-methyl-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-6-en-2-yl]oxyoxane-3,4,5-triol is a natural product found in Panax ginseng with data available.
Molecule SMILES: CNC(=O)OCc1cccc(Cl)c1Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2,3-Dichlorobenzyl methylcarbamate is a carbamate pesticide. 2,3-Dichlorobenzyl methylcarbamate is a carbamate pesticide, derived from carbamic acid and killing insects in a similar fashion to organophosphate insecticides. They are widely used in homes, gardens and agriculture. The first carbamate, carbaryl, was introduced in 1956 and more of it has been used throughout the world than all other carbamates combined. Because of carbaryl's relatively low mammalian oral and dermal toxicity and broad control spectrum, it has had wide use in lawn and garden settings. Most of the carbamates are extremely toxic to Hymenoptera, and precautions must be taken to avoid exposure to foraging bees or parasitic wasps. Some of the carbamates are translocated within plants, making them an effective systemic treatment. (L795)
Molecule SMILES: CC(=O)OC1C=C(C(C)C2CC(C)=C(C)C(=O)O2)C2(C)CCC3C(CC4OC45C(=O)C=CC(=O)C35C)C12O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Withangulatin I is a natural product found in Physalis angulata with data available.
Molecule SMILES: CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccccc2)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Plinabulin is a member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione substituted by benzylidene and (5-tert-butyl-1H-imidazol-4-yl)methylidene groups at positions 3 and 6, respectively. It is a vascular disrupting agent and a microtubule destabalising agent which was in clinical trials (now discontinued) for the treatment of non-small cell lung cancer. It has a role as a microtubule-destabilising agent, an antineoplastic agent, an apoptosis inducer and an angiogenesis inhibitor. It is a member of 2,5-diketopiperazines, a member of imidazoles, a member of benzenes and an olefinic compound.
Molecule SMILES: CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccccc2)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Plinabulin is an orally active diketopiperazine derivative with potential antineoplastic activity. Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule dynamics. This disrupts mitotic spindle assembly leading to cell cycle arrest at M phase and blockage of cell division. In addition, plinabulin may also inhibit growth of proliferating vascular endothelial cells, thereby disrupting the function of tumor vasculature that further contributes to a decrease in tumor cell proliferation.
Molecule SMILES: C=C1C(=O)OC2CC(C)C3C(O)CC(O)C3(C)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (3aalpha,7aalpha,9abeta)-3-Methylene-4abeta,8beta-dimethyl-5beta,7alpha-dihydroxydodecahydroazuleno[6,5-b]furan-2-one is a natural product found in Pentanema britannicum and Inula japonica with data available.
Molecule SMILES: C[Hg]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Methylmercury(.) is a methylmercury compound.
Molecule SMILES: O=S(c1ccccn1)S(=O)c1ccccn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2-[(S)-[(S)-pyridin-2-ylsulfinyl]sulfinyl]pyridine is a natural product found in Allium stipitatum with data available.
Molecule SMILES: CC(=O)c1cc(C)cc(C)c1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.
Molecule SMILES: CC(C)=CC(O)C(O)C1=CC(=O)OC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: aruncin A is a natural product found in Aruncus dioicus with data available.
Molecule SMILES: C=C1C2OC2C(OC(=O)C(C)=CC)C2(C)CCC3C(OC(=O)C(C)=CC)C(=O)OC3C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(1R,2S,5R,6R,9S,10S,11R,13R)-9-methyl-10-[(E)-2-methylbut-2-enoyl]oxy-14-methylidene-4-oxo-3,12-dioxatetracyclo[7.5.0.02,6.011,13]tetradecan-5-yl] (Z)-2-methylbut-2-enoate is a natural product found in Ferula varia with data available.