IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(OC2OC(CO)C(OC3OC(CO)C(O)C(OC4OC(COC5OC(CO)C(O)C(O)C5O)C(O)C(O)C4O)C3O)C(O)C2NC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-Acetamido-5-[(2S,3S,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyoxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide is an amino sugar.
Molecule SMILES: CCCCCCCCCCCC1=C(O)C(O)C=C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1S,4S)-3-undecylcyclohexa-2,5-diene-1,2,4,5-tetrol is a natural product found in Embelia ribes with data available.
Molecule SMILES: O=P(O)(O)OCC1OC(CO)(OP(=O)(O)O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [3,4-Dihydroxy-2-(hydroxymethyl)-5-(phosphonooxymethyl)oxolan-2-yl] dihydrogen phosphate is a natural product found in Homo sapiens with data available.
Molecule SMILES: CCC(C)C(=O)OCC12C(OC(C)=O)C(OC(C)=O)CC(C)(O)C13OC(C)(C)C(C(OC(=O)C(C)C)C2OC(=O)c1ccccc1)C3O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: [(1S,2S,4S,5R,6S,7S,8S,9S,12R)-4,5-diacetyloxy-2,12-dihydroxy-2,10,10-trimethyl-6-[[(2R)-2-methylbutanoyl]oxymethyl]-8-(2-methylpropanoyloxy)-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate is a natural product found in Celastrus angulatus with data available.
Molecule SMILES: CCS(=O)(=O)NC1CCC(CC(=O)NC2Cc3ccccc3C2)OC1CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-(2,3-dihydro-1H-inden-2-yl)-2-[(2R,5R,6R)-5-(ethylsulfonylamino)-6-(hydroxymethyl)-2-oxanyl]acetamide is a C-glycosyl compound.
Molecule SMILES: CC1=C(O)C(=O)C2C(C)(C)CCCC2(C)C1C=Cc1ccoc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 7-Hydroxy hedychenone is a natural product found in Hedychium spicatum and Hedychium coronarium with data available.
Molecule SMILES: COC(=O)CC1OC2(OC(C)CC(OC(C)=O)C2O)C2=C(C(=O)c3cccc(O)c3C2=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2S,9S,10S,3'S,4'S,6'S)-Griseusin E is a natural product found in Streptomyces with data available.
Molecule SMILES: CC(C)CC=CC(C)C1CCC2C3=CC(O)C4CC(O)CCC4(C)C3(O)CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (3S,5S,6R,9S,10S,13R,14R,17R)-10,13-dimethyl-17-[(E,2R)-6-methylhept-3-en-2-yl]-1,2,3,4,5,6,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,6,9-triol is a natural product found in Dendronephthya gigantea with data available.
Molecule SMILES: Cc1ccc(C(C)C)cc2c(C=O)ccc1-2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 11,12-Dihydrolactaroviolin is a natural product found in Lactarius deterrimus, Lactarius hatsudake, and Lactarius deliciosus with data available.
Molecule SMILES: CC(C)=CCCC(C)=CCc1c(-c2ccc(O)cc2O)oc2cc(O)c(CC=C(C)COS(=O)(=O)O)c(O)c2c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: ({4-[2-(2,4-dihydroxyphenyl)-3-(3,7-dimethylocta-2,6-dien-1-yl)-5,7-dihydroxy-4-oxo-4H-chromen-6-yl]-2-methylbut-2-en-1-yl}oxy)sulfonic acid is a member of flavones.
Molecule SMILES: CC(O)CCCC1CC2CC(O)CC(O)=C2C(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Peniciisocoumarin A is a natural product found in Penicillium with data available.
Molecule SMILES: CSC1=CC(=O)c2cn(C)c(=O)cc2C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-Methyl-6-methylsulfanylisoquinoline-3,5,8-trione is a natural product found in Biflustra perfragilis with data available.
Molecule SMILES: Cc1ccc2c(O)c3c(cc2c1)C(=O)c1ccc2c(c1C3=O)OC1OC2(C)C(O)C(N(C)C)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (1'S,2'R,3'R,4'R,5'R)-decilorene B is a natural product found in Streptomyces with data available.
Molecule SMILES: C[N+](C)(C)CCCC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 4-trimethylammoniobutanal is a member of butanals. It has a role as a mouse metabolite and a human metabolite.
Molecule SMILES: C[N+](C)(C)CCCC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 4-Trimethylammoniobutanal is a natural product found in Homo sapiens with data available.
Molecule SMILES: CC(O)CC(=O)OC(C)CC(=O)OC(C)CC(=O)OC(C)CC(=O)OC(C)CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoic acid is a (3R)-3-hydroxybutanoic acid oligomer resulting from the formal repeated intermolecular condensation of the hydroxy and carboxy groups of (3R)-3-hydroxybutanoic acid to give a chain in which five units of the monomer are linked together by four ester bonds. It is functionally related to a (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoic acid. It is a conjugate acid of a (3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-{[(3R)-3-hydroxybutanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoyl]oxy}butanoate.
Molecule SMILES: O=c1cc(-c2ccc(O)c(O)c2)oc2cc(OC3OCC(O)C(O)C3OC3OCC(O)C(O)C3O)c(O)c(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2-(3,4-dihydroxyphenyl)-7-[(2R,3R,4R,5S)-4,5-dihydroxy-3-[(2R,3R,4R,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5,6-dihydroxychromen-4-one is a natural product found in Veronica stenophylla with data available.
Molecule SMILES: CCCN(CC=CI)C1CCc2ccc(O)cc2C1.O=C(O)C=CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2-{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino}tetralin-7-ol maleate is a maleate salt obtained by reaction of 2-{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino}tetralin-7-ol with one equivalent of maleic acid. This ligand has uniquely high affinity and selectivity for the D3 receptor. It has a role as a dopamine agonist. It contains a 2-{[(2E)-3-iodoprop-2-en-1-yl](propyl)ammonio}tetralin-7-ol(1+).
Molecule SMILES: COC(=O)C1(C)C(OC(C)=O)CCC2(C)C3CCC(=CC(=O)N(C)CCO)C(C)C3C(O)C(=O)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (5alpha,8beta,10beta,14alpha)-16-[Methyl(2-hydroxyethyl)amino]-6,16-dioxo-3beta-acetoxy-7beta-hydroxycassa-13(15)-ene-19-oic acid methyl ester is a natural product found in Erythrophleum fordii with data available.
Molecule SMILES: CCCCCC=CCC(C=CC=CCCCCCCC(=O)O)OO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 12-HPE(8,10,14)TrE is a hydroperoxy fatty acid that is (8Z,10E,14Z)-icosatrienoic acid in which the hydroperoxy group is located at position 12. It is a long-chain fatty acid, an icosanoid and a hydroperoxy polyunsaturated fatty acid. It is a conjugate acid of a 12-HPE(8,10,14)TrE(1-).
Molecule SMILES: COc1cc(-c2cc(=O)c3c(O)cc(O)cc3o2)ccc1Oc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 2-[4-[4-(5,7-Dihydroxy-4-oxochromen-2-yl)-2-methoxyphenoxy]phenyl]-5,7-dihydroxychromen-4-one is a natural product found in Lonicera japonica with data available.
Molecule SMILES: COC(=O)CSC1=C(C#N)C(c2ccc(C)cc2)C2C(=O)CCCC2=N1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: LSM-19862 is a member of quinolines.
Molecule SMILES: O.O.O.O.O.OCC1OC(OCC2OC(OC3(CO)OC(CO)C(O)C3O)C(O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Raffinose Pentahydrate is an oligosaccharide.
Molecule SMILES: CC(C)=CCC1=C(O)C(C(=O)c2c(-c3cc(CC=C(C)C)c(O)cc3O)oc3c(CC=C(C)C)c(O)c(O)cc23)=CC2c3c(c4cc(CC=C(C)C)c(O)cc4oc3=O)OC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Lespecyrtin H2 is a natural product found in Lespedeza cyrtobotrya with data available.
Molecule SMILES: Cc1ccccc1-c1ccc(C2C3CN(C(=O)NC4CCCCC4)CC2N3)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1R,5S)-N-cyclohexyl-7-[4-(2-methylphenyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane-3-carboxamide is a member of piperidines.
Molecule SMILES: OCC1OC(SC(CCc2ccccc2)=NO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Desulfogluconasturtiin is a desulfoglucosinolic acid resulting from the formal condensation of the thiol group of N-hydroxy-3-phenylpropanethioamide with beta-D-glucopyranose. It has a role as an Arabidopsis thaliana metabolite.
Molecule SMILES: CC1=C(O)C(=O)C23C(=O)C1C(C)(C)C2CCC3C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1R,2R,5S,7R)-9-Hydroxy-2,6,6,8-tetramethyltricyclo[5.3.1.01,5]undec-8-ene-10,11-dione is a natural product found in Acourtia turbinata and Acourtia nana with data available.
Molecule SMILES: COc1cc(-c2coc3cc(O)cc(O)c3c2=O)c2c(c1O)OC(C)(C)C=C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Piscidanone is a natural product found in Piscidia piscipula with data available.
Molecule SMILES: CC(C=CC=C(C)C=CC=C(C)C=CC1=C(C)C(=O)C(O)CC1(C)C)=CC=CC(C)=CC=CC1=C(C)C(=O)C(O)CC1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-4,8,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1-one is a natural product found in Pecten maximus with data available.
Molecule SMILES: COC(=O)CCC(C)C1CC(=O)C2(C)C3=C(C(=O)CC12C)C1(C)CCC(O)C(C)(CO)C1CC3O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: methyl (4R)-4-[(3S,4R,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4-(hydroxymethyl)-4,10,13,14-tetramethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate is a natural product found in Ganoderma lucidum with data available.
Molecule SMILES: C#CC(Br)C1CC(O)C(C(Br)C2OC(CC)C(Br)CC2Br)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (2S,3R,5R)-2-[(R)-bromo-[(2S,3S,5R,6S)-3,5-dibromo-6-ethyloxan-2-yl]methyl]-5-[(1S)-1-bromoprop-2-ynyl]oxolan-3-ol is a natural product found in Laurencia obtusa and Laurencia dendroidea with data available.
Molecule SMILES: CC(C)C(C)C=CC(C)C1CCC2=C3C(O)C4OC45CC(O)CCC5(C)C3CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 5alpha,6alpha-Epoxyergosta-8(14),22-diene-3beta,7alpha-diol is a natural product found in Topsentia, Momordica charantia, and other organisms with data available.
Molecule SMILES: CNCC1Oc2ccc(NC(=O)CCC(F)(F)F)cc2C(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 4,4,4-trifluoro-N-[(2R,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]butanamide is an aromatic amide.
Molecule SMILES: Cc1c[nH]c(C=C2C(=O)Nc3ccccc32)c1CCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: SU5402 is an oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 3-(2-carboxyethyl)-4-methyl-1H-pyrrol-2-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1. It has a role as a fibroblast growth factor receptor antagonist. It is a monocarboxylic acid, a member of pyrroles and a member of oxindoles. It is functionally related to a 3-methyleneoxindole.
Molecule SMILES: CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-1-oxoethyl]amino]-1-oxoethyl]amino]-1-oxo-3-phenylpropyl]amino]-4-methylpentanoic acid is a peptide.
Molecule SMILES: COc1cc(C=CC(=O)OCC2OC(CO)(OC3OC(COC(C)=O)C(O)C(O)C3O)C(OC(=O)C=Cc3ccc(O)c(OC)c3)C2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(2R,3R,4S,5S)-5-[(2R,3R,4S,5R,6R)-6-(acetyloxymethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxy-4-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]oxy-5-(hydroxymethyl)oxolan-2-yl]methyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate is a natural product found in Smilax bracteata and Persicaria perfoliata with data available.
Molecule SMILES: COc1ccc2cc1Oc1cc3c(cc1OC)CCN(C(C)=O)C3Cc1ccc(cc1)Oc1c3c(cc4c1C(C2)N(C)CC4)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (-)-Curicycleatjenine is a natural product found in Cyclea atjehensis with data available.
Molecule SMILES: CCCCCCC(C)CC(NC(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)CC(O)CC(=O)CC)NC(=O)C1CCCN1C(=O)CCC)C(=O)NC(CC(C)C)C(=O)NC(C)(C)C(=O)NC(CC(C)C)C(=O)NCCC(=O)NC(C)CNCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Culicinin A is a natural product found in Culicinomyces with data available.
Molecule SMILES: CC(CCCC(C)(C)O)C1CCC2C3C(O)CC4CC(OC5OC(C(=O)O)C(O)C(O)C5O)CCC4(C)C3CC(O)C12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Cholestane-3,7,12,25-tetrol-3-glucuronide is a steroid saponin.
Molecule SMILES: CC1CN(C(C)CO)C(=O)CCCn2cc(nn2)COC1CN(C)C(=O)Nc1ccccc1C(F)(F)F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[2-(trifluoromethyl)phenyl]urea is an azamacrocycle and a lactam.
Molecule SMILES: COC(=O)C1=CCCN(C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Arecoline is a tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine. It has a role as a muscarinic agonist and a metabolite. It is a tetrahydropyridine, an enoate ester, a pyridine alkaloid and a methyl ester.
Molecule SMILES: COC(=O)C1=CCCN(C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
Molecule SMILES: COC(=O)C1=CCCN(C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Arecoline is a natural product found in Piper betle and Areca catechu with data available.
Molecule SMILES: COC(=O)C1=CCCN(C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (Areca catechu). It is an oily liquid that is soluble in water, alcohols, and ether. Owing to its muscarinic and nicotinic agonist properties, arecoline has shown improvement in the learning ability of healthy volunteers. Since one of the hallmarks of Alzheimer's disease is a cognitive decline, arecoline was suggested as a treatment to slow down this process and arecoline administered via i.v. route did indeed show modest verbal and spatial memory improvement in Alzheimer's patients, though due to arecoline's possible carcinogenic properties, it is not the first drug of choice for this degenerative disease. Arecoline has been shown to exhibit apoptotic, excitant and steroidogenic functions (A7876, A7878, A7879). Arecoline belongs to the family of Alkaloids and Derivatives. These are naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and more rarely other elements such as chlorine, bromine, and phosphorus.
Molecule SMILES: CC(C)=CC(=O)C=C(C)C1CC=C(C)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (Z)-alpha-Atlantone is a natural product found in Curcuma longa with data available.
Molecule SMILES: CCCCP(CCCC)CCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Tributylphosphine is a colorless to yellowish liquid with a strong garlic-like odor. It is insoluble in water. It is liable to heat and ignite spontaneously in air. If involved in a fire phosphine gas, a highly flammable and toxic gas, will evolve. It is irritating to mucous membranes.
Molecule SMILES: COC(=O)C12COCC=C3CN(CCC31)Cc1c2[nH]c2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Angustilobine B, (rac)- is an alkaloid. It has a role as a metabolite.
Molecule SMILES: COC(=O)C12COCC=C3CN(CCC31)Cc1c2[nH]c2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: angustilobine B, (rac)- is a natural product found in Alstonia angustiloba with data available.
Molecule SMILES: CC(C)C1CCC2C1(C)C(O)CC1(C)C3=C(C(=O)CC21C)C1(C)CCC(O)C(C)(C)C1CC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3alpha,16alpha-Dihydroxyferna-8-ene-11-one is a natural product found in Lonicera gracilipes with data available.
Molecule SMILES: COC(=O)C1=CCCC2CC(C(C)=O)=CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: methyl (3aR,7aR)-2-acetyl-3a,6,7,7a-tetrahydro-1H-indene-4-carboxylate is a natural product found in Ligularia lapathifolia with data available.