IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COC(=O)c1ccc(O)c(NC(=O)CCC2(C)C(=O)C=CC34CC(CCC32)C(O)(CO)C4)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Platensimycin A5 methyl ester is a polycyclic cage compound that is the methyl ester derivative of the dihydroxy substituted platensimycin. It is isolated from Streptomyces platensis. It has a role as a bacterial metabolite. It is a cyclic ether, a cyclic ketone, a polycyclic cage, a diol, a benzoate ester, an aromatic amide and a monocarboxylic acid amide. It is functionally related to a platensimycin.
Molecule SMILES: O=C(O)CN(CC(=O)O)CC(=O)O.[Fe]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Iron(III) nitrilotriacetate is an iron chelate resulting from the combination of equimolar amounts of iron(3+) and nitrilotriacetate(3-). It has a role as a carcinogenic agent and a mutagen. It contains a nitrilotriacetate(3-) and an iron(3+).
Molecule SMILES: Oc1ccc(C2Oc3cc(O)ccc3C(O)C2O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3,4,4',7-Tetrahydroxyflavan is a natural product found in Acacia cultriformis and Vachellia luederitzii with data available.
Molecule SMILES: COC12NC(=O)NC1CC(CNC(=O)c1cc(Br)c[nH]1)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Slagenin C is a natural product found in Agelas nakamurai with data available.
Molecule SMILES: Cc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-(3,4-dimethylphenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide is a member of quinolines.
Molecule SMILES: CC(=CCNc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)O)C(O)C1O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 9-ribosyl-trans-zeatin 5'-diphosphate is a purine ribonucleoside 5'-diphosphate that is ADP substituted at position N-6 by a (2E)-4-hydroxy-3-methylbut-2-en-1-yl group. It has a role as a plant metabolite. It is a N-glycosylzeatin, an adenosine 5'-phosphate and a purine ribonucleoside 5'-diphosphate. It is functionally related to an ADP. It is a conjugate acid of a 9-ribosyl-trans-zeatin 5'-diphosphate(3-).
Molecule SMILES: CC(=CCNc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)O)C(O)C1O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: trans-Zeatin riboside diphosphate is a natural product found in Brassica napus and Apis cerana with data available.
Molecule SMILES: Nc1cc(N)c(N=Nc2ccc(S(N)(=O)=O)cc2)c(C(=O)O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Sulfachrysoidine is a member of azobenzenes.
Molecule SMILES: Nc1cc(N)c(N=Nc2ccc(S(N)(=O)=O)cc2)c(C(=O)O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Sulfachrysoidine is a lipid-soluble azo dye and sulfonamide antibacterial agent.
Molecule SMILES: C=C(C)CC(O)CC(C)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(C2OC(CO)C(O)C(OC4OC(C)C(O)C(O)C4O)C2OC2OC(C)C(O)C(OC4OC(CO)C(O)C(O)C4O)C2O)C(O)(CO)C1CC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Feroxoside A is a natural product found in Ectyoplasia ferox with data available.
Molecule SMILES: C=C1C(=O)OC2C=C(C)C(=O)CC=C(C)CC(OC(=O)C(C)=CC)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(3aR,4S,6E,10Z,11aR)-6,10-dimethyl-3-methylidene-2,9-dioxo-4,5,8,11a-tetrahydro-3aH-cyclodeca[b]furan-4-yl] (E)-2-methylbut-2-enoate is a natural product found in Chamaemelum nobile with data available.
Molecule SMILES: CCNc1nc(CC)c(C(=O)NC(C#N)c2cccs2)s1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (S)-ethaboxam is an N-[cyano(2-thienyl)methyl]-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide that is the (S)-enantiomer of ethaboxam. It is an enantiomer of a (R)-ethaboxam.
Molecule SMILES: COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc1ccccc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 4,5-dimethoxy-2-[[(2-methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester is a methoxybenzoic acid.
Molecule SMILES: CC(C)C1CCC(C)(N=C=S)C2(O)CCC(C)(O)C=C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Axinisothiocyanate G is a natural product found in Axinyssa with data available.
Molecule SMILES: CC(=CC(O)C(C)O)C1CCC2C3=CC(=O)C4CC(=CCC(O)C4)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2R,5R,6R,9R,13S,15R)-6-[(E,4S,5R)-4,5-dihydroxyhex-2-en-2-yl]-15-hydroxy-5-methyltetracyclo[11.4.1.02,10.05,9]octadeca-1(17),10-dien-12-one is a natural product found in Penicillium citrinum with data available.
Molecule SMILES: CN1C(=O)c2cc(NC(=O)c3cnccn3)ccc2OCC2OC(CC(=O)NC3CCN(Cc4ccccc4)C3)CCC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N-[(2S,4aS,12aR)-5-methyl-6-oxo-2-[2-oxo-2-[[(3S)-1-(phenylmethyl)-3-pyrrolidinyl]amino]ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-pyrazinecarboxamide is a member of pyrazines, a secondary carboxamide and a tertiary carboxamide.
Molecule SMILES: COc1cc(OC)c(OC)cc1C=CC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (Z)-3-(2,4,5-Trimethoxyphenyl)-2-propenal is a member of cinnamaldehydes.
Molecule SMILES: COc1cc(OC)c(OC)cc1C=CC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (Z)-3-(2,4,5-Trimethoxyphenyl)-2-propenal is a natural product found in Acorus calamus with data available.
Molecule SMILES: Nc1c(C(=O)NC(CC(=O)O)C(=O)O)ncn1C1OC(COP(=O)(O)O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: COc1ccc2c(c1O)C(=O)N1CCc3cc4c(cc3C1C2)OCO4

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Gusanlung A is a natural product found in Arcangelisia gusanlung with data available.
Molecule SMILES: O=C1CC(c2ccc(O)c(O)c2)Oc2c1ccc(OC1OC(CO)C(O)C(O)C1O)c2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (R)-2-(3,4-Dihydroxyphenyl)-8-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one is a natural product found in Coreopsis with data available.
Molecule SMILES: C=C1C(=O)OC2CC(C)C3C(O)CC(OC(=O)C(C)=CC)C3(C)C(O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(3aR,5R,5aS,6S,8R,8aR,9S,9aS)-6,9-dihydroxy-5,8a-dimethyl-1-methylidene-2-oxo-4,5,5a,6,7,8,9,9a-octahydro-3aH-azuleno[6,7-b]furan-8-yl] (E)-2-methylbut-2-enoate is a natural product found in Arnica angustifolia with data available.
Molecule SMILES: CCC(C)C(=O)OCC1OC1c1ccc(OC(=O)C(C)C)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [(2R,3S)-3-[3-methoxy-4-(2-methylpropanoyloxy)phenyl]oxiran-2-yl]methyl (2R)-2-methylbutanoate is a natural product found in Cosmos caudatus with data available.
Molecule SMILES: Brc1ccc(Oc2ccccc2Br)cc1Br

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Tribromodiphenyl ethers are organobromine compounds, as well as polybrominated diphenyl ethers containing three bromine atoms. Polybrominated diphenyl ethers (PBDEs) are flame-retardant man-made chemicals found in plastics used in a variety of consumer products to make them difficult to burn. PBDEs exist as mixtures of similar chemicals called congeners. Because they are mixed into plastics and foams rather than bound to them, PBDEs can leave the products that contain them and enter the environment. (L628)
Molecule SMILES: CC1OC(OC2C=CC(C#N)(OC3OC(CO)C(O)C(O)C3O)C2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Passibiflorin is a natural product found in Passiflora biflora, Passiflora talamancensis, and Passiflora lutea with data available.
Molecule SMILES: COc1c(O)c(OC)c2oc(-c3ccc4c(c3)OCO4)c(OC)c(=O)c2c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 2-(1,3-Benzodioxol-5-yl)-7-hydroxy-3,5,6,8-tetramethoxy-4H-1-benzopyran-4-one is a member of flavonoids and an ether.
Molecule SMILES: COc1c(O)c(OC)c2oc(-c3ccc4c(c3)OCO4)c(OC)c(=O)c2c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-(1,3-Benzodioxol-5-yl)-7-hydroxy-3,5,6,8-tetramethoxy-4H-1-benzopyran-4-one is a natural product found in Comptonella microcarpa with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)c2cc(NC(=O)Cc3ccccc3)ccc2OC1CN(C)Cc1ccc2c(c1)OCO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-[(2S,3S)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-phenylacetamide is a member of acetamides.
Molecule SMILES: CC1=CC(O)CC(C)(O)C=CC(C(C)C)CCC(C)=CCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Cembra-2,7,11-triene-4,6-diol is a cembrane diterpenoid obtained from tobacco and shown to have antitumour-promoting activity. It has a role as an antineoplastic agent.
Molecule SMILES: CC1=CC(O)CC(C)(O)C=CC(C(C)C)CCC(C)=CCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Cembra-2,7,11-triene-4,6-diol is a natural product found in Nicotiana sylvestris and Nicotiana tabacum with data available.
Molecule SMILES: C=C1CCC2CCC3C(=O)NC(=CC(C)CC(O)C1)C3(O)C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (5R,10S)-5,16-dihydroxy-3,17,17-trimethyl-7-methylidene-15-azatricyclo[8.5.2.013,16]heptadec-1-en-14-one is a natural product found in Conglomeratusclera coerulea with data available.
Molecule SMILES: O=CN(O)CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Hadacidin is a monocarboxylic acid that is N-hydroxyglycine in which the hydrogen attached to the nitrogen is replaced by a formyl group. It was originally isolated from cultures of Penicillium frequentans. It has a role as a teratogenic agent, an antineoplastic agent, an antimicrobial agent and a Penicillium metabolite. It is a monocarboxylic acid, a N-hydroxy-alpha-amino-acid and an aldehyde.
Molecule SMILES: CC1(C)CC23C1CCC2(C)CCCC3(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2aS,4aR,8S,8aS)-2,2,4a,8-tetramethyl-2a,3,4,5,6,7-hexahydro-1H-cyclobuta[i]inden-8-ol is a natural product found in Panax ginseng with data available.
Molecule SMILES: O=C(OCCOCCN1CCCCC1)N1c2ccccc2Sc2cccnc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Pipazetate is an aryl sulfide.
Molecule SMILES: O=C(OCCOCCN1CCCCC1)N1c2ccccc2Sc2cccnc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: A non-narcotic oral antitussive agent.
Molecule SMILES: CC(=CC=CC=CC=CC=CCCC=CC(C)C(O)C(C)C(O)C=CC=CC=CC=CC=CCC(O)C(C)C(=O)CC(O)CC(O)CC(O)C=CCC(O)CC(O)CC(O)CC(O)C=CCC(O)C=CCC(O)CC(O)CCCCN)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Linearmycin C is a natural product found in Streptomyces with data available.
Molecule SMILES: C=C(C)C1CCC2(C(=O)O)CCC3(C)C4(C)CCC5C(C)(C)C(O)CCC5(C)C4CCC3(O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Terminic acid is a natural product found in Terminalia arjuna with data available.
Molecule SMILES: C=C(C)c1ccncc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Pyridine, 4-(1-methylethenyl) is a natural product found in Mentha arvensis with data available.
Molecule SMILES: CN=C(N)N.CN=C(N)N.O=S(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1-Methylguanidine sulfate (2:1) is an organic sulfate.
Molecule SMILES: CC(C)=CCCC(C)=CCc1c(O)cc2cc(CCc3ccc(O)cc3)oc(=O)c2c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Achlisocoumarin I is a natural product found in Achlys triphylla with data available.
Molecule SMILES: CC1C(=O)CC(O)C(C)(C)C12CC=C(CO)CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Acaciicolinol J is a natural product found in Pseudolagarobasidium acaciicola with data available.
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)OCC1OC(Oc2cc(O)cc3[o+]c(-c4cc(O)c(O)c(O)c4)c(OC4OC(CO)C(O)C(O)C4O)cc23)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Delphinidin 3-O-beta-D-glucoside 5-O-(6-coumaroyl-beta-D-glucoside) is an anthocyanidin glycoside.
Molecule SMILES: OCC1OC(OC2C(O)C(CO)OC(OCc3ccccc3)C2OC2OCC(O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Xyl(b1-2)[Glc(b1-3)]Glc(b)-O-Bn is a natural product found in Sesamum indicum with data available.
Molecule SMILES: C=C1CC(OC(=O)Cc2ccc(O)cc2)C2C(=C)C(=O)OC2C2C(=C)C(OC3OC(CO)C(O)C(O)C3O)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (3abeta,4R,6abeta,9abeta,9balpha)-3,6,9-Trismethylene-4alpha-(4-hydroxyphenylacetyloxy)-8alpha-(beta-D-glucopyranosyloxy)dodecahydroazuleno[4,5-b]furan-2-one is a natural product found in Ixeris japonica, Crepis tingitana, and Ixeris chinensis with data available.
Molecule SMILES: C=C1CC(O)CC2(C)CC3OC(=O)C(C)C3CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 11,13-Dihydroivalin is a natural product found in Dittrichia graveolens and Carpesium macrocephalum with data available.
Molecule SMILES: CC(=O)c1ccc(OC=C(C)C)c(C=O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 5-Acetyl-2-[(2-methylprop-1-en-1-yl)oxy]benzaldehyde is a natural product found in Kleinia galpinii and Osteospermum muricatum with data available.
Molecule SMILES: CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(O)CNC(=O)C2C(O)CCN2C(=O)C(C(O)CC(N)=O)NC(=O)C(C(O)C(O)c2ccc(O)cc2)NC(=O)C2CC(O)CN2C(=O)C(C(C)O)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[(3S,6S,9S,11R,15S,18S,20R,24S,25S)-3-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl]-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-18-yl]-10,12-dimethyltetradecanamide is a natural product found in Lophium arboricola with data available.
Molecule SMILES: CC(=O)CCC=C1CC(C=C(C)C)OC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (3E,5S)-5-(2-methylprop-1-enyl)-3-(4-oxopentylidene)tetrahydrofuran-2-one is a natural product found in Heteroplexis microcephala with data available.
Molecule SMILES: COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C2C(C)C(O)C(O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 6-beta-hydroxy-Loganin is a natural product found in Nyctanthes arbor-tristis with data available.
Molecule SMILES: CCCCCCCC(O)CCCC1Cc2cc(O)cc(O)c2CO1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (3R)-3-[(4S)-4-hydroxyundecyl]-3,4-dihydro-1H-isochromene-6,8-diol is a natural product found in Ononis natrix with data available.
Molecule SMILES: CC(=O)N1CCN(c2ccc(CN(C(=O)C=Cc3ccc(C(C)(C)C)cc3)C(Cc3ccccc3)C(=O)N3CCN(Cc4ccc(C#N)cc4)CC3)cc2)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: ACT-451840 has been used in trials studying Malaria.
Molecule SMILES: C=CCN1CCC23c4c5ccc(O)c4OC2C(=O)CCC3(O)C1C5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Naloxone is an opiate antagonist which is used intravenously in emergency situations to reverse the respiratory depression caused by overdoses of heroin, morphine or other opioids. Naloxone has not been linked to serum enzyme elevations during therapy or to clinically apparent liver injury.
Molecule SMILES: C=CCN1CCC23c4c5ccc(O)c4OC2C(=O)CCC3(O)C1C5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Naloxone is a synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose. It has a role as a mu-opioid receptor antagonist, a central nervous system depressant and an antidote to opioid poisoning. It is an organic heteropentacyclic compound, a morphinane alkaloid and a tertiary alcohol. It is a conjugate base of a naloxone(1+). It derives from a hydride of a morphinan.
Molecule SMILES: C=CCN1CCC23c4c5ccc(O)c4OC2C(=O)CCC3(O)C1C5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Naloxone is an Opioid Antagonist. The mechanism of action of naloxone is as an Opioid Antagonist.