IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=CC1(C)CC(OC(=O)CSC2CC3CCC(C2)N3C)C2(C)C(C)CCC3(CCC(=O)C32)C(C)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: SW219106-1 is a carboxylic ester, a carbotricyclic compound and a cyclic ketone.
Molecule SMILES: O=C(O)CCCCCCCCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 10-hydroxycapric acid is a 10-carbon, omega-hydroxy fatty acid, shown to be the preferred hydroxylation product (together with the 9-OH isomer) of capric acid in biosystems, and used as a standard in lipid assays; reported to have cytotoxic effects. It is a straight-chain saturated fatty acid and an omega-hydroxy-medium-chain fatty acid. It is functionally related to a decanoic acid. It is a conjugate acid of a 10-hydroxycaprate.
Molecule SMILES: O=C(O)CCCCCCCCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 10-Hydroxydecanoic acid is a natural product found in Trypanosoma brucei with data available.
Molecule SMILES: CC1CCC2C1CC(C(C)(C)O)CCC2(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 10alpha,11-Dihydroxyguaiane is a natural product found in Pithomyces with data available.
Molecule SMILES: COc1c(O)cc2oc3cc4c(c(O)c3c(=O)c2c1CCC(C)(C)OC)CCC(C)(C)O4

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 5,9-Dihydroxy-8-methoxy-7-(3-methoxy-3-methylbutyl)-2,2-dimethyl-3,4-dihydropyrano[3,2-b]xanthen-6-one is a natural product found in Cratoxylum formosum with data available.
Molecule SMILES: COC(=O)Cc1cc(OC)cc(O)c1C(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-Acetyl-3-hydroxy-5-methoxyphenylacetic acid methyl ester is a natural product found in Penicillium canescens with data available.
Molecule SMILES: Cc1cc(Oc2cnn(C(C)(C)C)c(=O)c2Cl)cc(C(C)C)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-tert-butyl-4-chloro-5-(3-methyl-5-propan-2-ylphenoxy)-3-pyridazinone is an aromatic ether.
Molecule SMILES: COCCN(CC1C(c2ccccc2)C(CO)N1C(=O)C1CCC1)C(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: N-[[(2R,3R,4R)-1-[cyclobutyl(oxo)methyl]-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-N-(2-methoxyethyl)acetamide is a member of benzenes, a member of azetidines and a ring assembly.
Molecule SMILES: CC12CCOC1C1=CCC3C(C)(CO)CCCC3(C)C1CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(3aS,5aR,6R,9aS,9bR,11aR)-6,9a,11a-trimethyl-2,3a,5,5a,7,8,9,9b,10,11-decahydro-1H-naphtho[1,2-g][1]benzofuran-6-yl]methanol is a natural product found in Xylaria longipes with data available.
Molecule SMILES: CC(=O)OC1C=C2C(=CCC3C(C)(C)C(=O)CCC23C)C2(C)CCC(C(C)CCC=C(C)C(=O)O)C12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (Z,6R)-6-[(5R,10S,12R,13R,14S,17R)-12-acetyloxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid is a natural product found in Pappia fissilis with data available.
Molecule SMILES: CC(=O)OC1C(O)COC(OC2CCC34CC35CCC3(C)C(C6(C)CCC(C(C)(C)O)O6)C(O)CC3(C)C5CC(OC3OC(CO)C(O)C(O)C3O)C4C2(C)C)C1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(2S)-3-acetyloxy-5-hydroxy-2-[[(1S,3R,8S,11S,12S,15S,16R)-14-hydroxy-15-[(2R)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-9-[(2R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]oxan-4-yl] acetate is a natural product found in Astragalus mongholicus and Astragalus membranaceus with data available.
Molecule SMILES: O=C1CCC2=C1C1=CCCOC1OC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2,3,4a,6,7,8-Hexaahydro-pyrano[2,3-b]cyclopenta[d]pyran-9-one is a natural product found in Actinoalloteichus nanshanensis with data available.
Molecule SMILES: CCC(C)C(NC(=O)NC(C(=O)NC1C=CCCNC(=O)C=CC(C(C)C)NC1=O)C(C)CC)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-[[1-[(2,7-Dioxo-5-propan-2-yl-1,6-diazacyclododeca-3,9-dien-8-yl)amino]-3-methyl-1-oxopentan-2-yl]carbamoylamino]-3-methylpentanoic acid is a natural product found in Pseudomonas syringae with data available.
Molecule SMILES: CCN(CCCl)CCCl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Ethylbis(2-chloroethyl)amine is a dark liquid with a faint, fishy amine odor. Used as a delayed-action, military casualty agent.
Molecule SMILES: COC1=C(OC)C(=O)C(c2coc3cc(OC)ccc3c2=O)=CC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2,3-Dimethoxy-5-(7-methoxy-4-oxochromen-3-yl)cyclohexa-2,5-diene-1,4-dione is a natural product found in Amburana cearensis with data available.
Molecule SMILES: C=C(CCC=C(C)C)C1CCC2(C)C1CCC1C3(C)CCC(OC(C)=O)C(C)(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Dammaradienyl acetate is a natural product found in Syncarpha gnaphaloides, Nardophyllum lanatum, and other organisms with data available.
Molecule SMILES: CC=Cc1ccc2n(c1=O)CC1C(CO)C(C(=O)NCC)N(C(=O)CC3CC3)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: LSM-14585 is an amino acid amide.
Molecule SMILES: O=C1C(O)=Cc2cc(O)c(O)c3ccc(-c4ccccc4)c1c23

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2,5,6-Trihydroxy-9-phenyl-1H-phenalen-1-one is a natural product found in Wachendorfia paniculata and Wachendorfia thyrsiflora with data available.
Molecule SMILES: O=C(NC1CCC(CCNC(=O)C2CCOCC2)OC1CO)c1ccncc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: N-[(2R,3R,6R)-2-(hydroxymethyl)-6-[2-[[4-oxanyl(oxo)methyl]amino]ethyl]-3-oxanyl]-4-pyridinecarboxamide is a C-glycosyl compound.
Molecule SMILES: CCCC(=O)NCC(=O)c1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N-[2-(4-Hydroxyphenyl)-2-oxoethyl]butanamide is a member of acetophenones. It has a role as a metabolite.
Molecule SMILES: CCCC(=O)NCC(=O)c1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-[2-(4-hydroxyphenyl)-2-oxoethyl]butanamide is a natural product found in Cystobacter ferrugineus with data available.
Molecule SMILES: NC(=O)NCC(N)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: ALBIZZIINE is an alpha-amino acid.
Molecule SMILES: COc1cc2c(cc1O)-c1c3c(cc4c1C(C2)N(C)CC4)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (-)-Phanostenine is a natural product found in Stephania pierrei and Stephania corymbosa with data available.
Molecule SMILES: Nc1ccc2cc3ccc(N)cc3[n+](CCCC(=O)O)c2c1.[O-][Cl+3]([O-])([O-])[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: ATTO 465-2 is a member of aminoacridines and an organic perchlorate salt. It has a role as a fluorochrome. It contains an ATTO 465-2(1+).
Molecule SMILES: COC1(C)CC2OC(C)C(C)c3c(C)c(O)cc(c32)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Penicitrinol D is a natural product found in Penicillium chrysogenum and Penicillium citrinum with data available.
Molecule SMILES: OCC1OC(OCC2OC(OCc3ccccc3)C(O)C(O)C2O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Benzyl 6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranoside is a natural product found in Rhodiola rosea and Rhodiola sachalinensis with data available.
Molecule SMILES: C=CC1=CC(=O)C2C(CCC3C(C)(C)C(O)C(O)C(O)C23C)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: phytocassane B is a natural product found in Oryza sativa with data available.
Molecule SMILES: CC(O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Pregn-5-ene-3beta,20beta-diol is a corticosteroid hormone.
Molecule SMILES: C=C1C(=O)OC2CC(C)C3C(O)CC(O)C3(C)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Pulchellin is a natural product found in Gaillardia pulchella, Gaillardia coahuilensis, and Gaillardia aristata with data available.
Molecule SMILES: CC1CC(=O)c2c(CO)coc2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-(Hydroxymethyl)-6-methyl-6,7-dihydro-1-benzofuran-4(5H)-one is a natural product found in Phomopsis with data available.
Molecule SMILES: COc1cc2oc(=O)ccc2c(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5,6,7-trimethoxycoumarin is a member of the class of coumarins that is coumarin substituted by methoxy groups at positions 5, 6 and 7. It has a role as an antibacterial agent and a metabolite. It is an aromatic ether and a member of coumarins. It is functionally related to a coumarin.
Molecule SMILES: COc1cc2oc(=O)ccc2c(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 5,6,7-Trimethoxycoumarin is a natural product found in Pelargonium sidoides, Artemisia capillaris, and other organisms with data available.
Molecule SMILES: CC([NH3+])C(=O)NC(CCCC[NH3+])C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Ala-Lys(1+) is a peptide cation obtained by deprotonation of the carboxy terminus and protonation of the side-chain amino groups and the amino terminus of Ala-Lys; major species at pH 7.3. It is a conjugate acid of a member of Ala-Lys.
Molecule SMILES: CC1C(=O)N2c3ccccc3C3(O)CC4C(=O)NC(c5nc6ccccc6c(=O)n54)N1C23

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Versiquinazoline L is a natural product found in Aspergillus versicolor with data available.
Molecule SMILES: O=CN1CC2CC(C1)c1cccc(=O)n1C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (1R,9R)-6-oxo-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-diene-11-carbaldehyde is a natural product found in Thermopsis chinensis, Ulex airensis, and other organisms with data available.
Molecule SMILES: C=C(C)C1CCC2(C)CCC3C(CCC4C3(C)CCC3C(C)(C)C(O)CCC34C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (1R,3aR,5aR,5bS,7aR,9R,11aR,11bS,13aS,13bS)-3a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-2,3,4,5,5a,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydro-1H-cyclopenta[a]chrysen-9-ol is a natural product found in Myrtopsis myrtoidea and Myrtopsis macrocarpa with data available.
Molecule SMILES: O=C(Cc1ccccc1)NC(Cc1c[nH]c2ccccc12)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N-(Phenylacetyl)-L-tryptophan is a natural product found in Streptomyces with data available.
Molecule SMILES: COc1c(O)ccc(C(=O)O)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 4-hydroxy-2,3-dimethoxybenzoic acid is a methoxybenzoic acid.
Molecule SMILES: CC1=CC(O)CC(=O)Cc2nc(co2)C(=O)N2CCCC2C(=O)OC(C(C)C)C(C)C=CC(=O)NCC=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (10R,11R,12Z,17Z,19Z,21S)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone is a natural product found in Streptomyces virginiae with data available.
Molecule SMILES: COc1cc(C2OC2C(=O)O)cc(OC)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-(4-hydroxy-3,5-dimethoxyphenyl)oxirane-2-carboxylic acid is a member of methoxybenzenes and a member of phenols.
Molecule SMILES: CC(=O)OC1CC2C(C)(C)OC3CC(=O)OC32CC2(O)CCC34OC(C5C=C(C)C(=O)O5)C(C)C3CC(O)C4(C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [1,15-dihydroxy-9,9,14,18-tetramethyl-19-(4-methyl-5-oxo-2H-furan-2-yl)-5-oxo-4,8,20-trioxahexacyclo[11.10.0.03,7.03,10.014,21.017,21]tricosan-12-yl] acetate is a natural product found in Schisandra chinensis with data available.
Molecule SMILES: CC1CC(O)CC2(C)CCC(=O)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2R-hydroxy-7-oxogeosmin is a natural product found in Streptomyces with data available.
Molecule SMILES: NC(N)=NCCC(O)CC(N)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2R,4S)-2-amino-6-(diaminomethylideneamino)-4-hydroxyhexanoic acid is a natural product found in Lathyrus tingitanus with data available.
Molecule SMILES: OCC1OC(OC2C(O)C(O)OC(CO)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: D-Manp-(1->3)-D-Manp is a glycosylmannose consisting of two D-mannopyranose residues joined by a (1->3) glycosidic bond. It is a glycosylmannose and a partially-defined glycan. It is functionally related to a D-mannopyranose.
Molecule SMILES: CC(C)C(=O)OC1CCC2(C)C(CC(O)C3(C)C2CCC24CC23CCC4C2CC(C3OC3(C)C)OC2O)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(1S,2R,3R,5S,7S,10S,11R,14R,15S)-15-[(2S,3S,5R)-5-[(2S)-3,3-dimethyloxiran-2-yl]-2-hydroxyoxolan-3-yl]-3-hydroxy-2,6,6,10-tetramethyl-7-pentacyclo[12.3.1.01,14.02,11.05,10]octadecanyl] 2-methylpropanoate is a natural product found in Owenia acidula with data available.
Molecule SMILES: O=S(O)S(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Dithionous acid is a sulfur oxoacid. It is a conjugate acid of a dithionite(1-).
Molecule SMILES: CC=C(C)C(=O)OC1CCC2(O)CC3OC(=O)C(C)=C3CC2(C)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2-Butenoic acid, 2-methyl-, (4aR,5R,6S,8aS,9aS)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-8a-hydroxy-3,4a,5-trimethyl-2-oxonaphtho(2,3-b)furan-6-yl ester, (2Z)- is a natural product found in Hertia cheirifolia with data available.
Molecule SMILES: C=CCCCC=CC=CCCCCCCCCc1cc(O)cc(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 5-[(9E,11Z)-9,11,16-Heptadecatrienyl]-1,3-benzenediol is a natural product found in Merulius incarnatus and Gloeostereum incarnatum with data available.
Molecule SMILES: O=C(O)C(=O)Cc1c[nH]c2ccc(OCc3ccccc3)cc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3-(5-benzyloxyindol-3-yl)pyruvic acid is a pyruvic acid having a 5-benzyloxyindol-3-yl group at the 3-position. It is functionally related to a pyruvic acid. It is a conjugate acid of a 3-(5-benzyloxyindol-3-yl)pyruvate.
Molecule SMILES: O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Niclosamide is a secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections. It has a role as a piscicide, a molluscicide, an antiparasitic agent, an anticoronaviral agent, an anthelminthic drug, an apoptosis inducer and a STAT3 inhibitor. It is a member of monochlorobenzenes, a member of salicylanilides, a C-nitro compound, a secondary carboxamide and a member of benzamides. It is functionally related to a 5-chlorosalicylic acid.
Molecule SMILES: O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Niclosamide is an antihelminthic used for the treatment of tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals.  Niclosamide, once marketed in the US under the brand name Niclocide, was voluntarily withdrawn from market by Bayer in 1996.
Molecule SMILES: O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Niclosamide is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Upon oral administration, niclosamide specifically induces degradation of the androgen receptor (AR) variant V7 (AR-V7) through the proteasome-mediated pathway. This downregulates the expression of the AR variant, inhibits AR-V7-mediated transcriptional activity, and reduces AR-V7 recruitment to the prostate-specific antigen (PSA) gene promoter. Niclosamide also prevents AR-V7-mediated STAT3 phosphorylation and activation. This inhibits AR/STAT3-mediated signaling and prevents expression of STAT3 target genes. Altogether, this may inhibit growth of AR-V7-overexpressing cancer cells. The AR-V7 variant, which is encoded by contiguous splicing of AR exons 1/2/3/CE3, is upregulated in a variety of cancer cell types, and is associated with both cancer progression and resistance to AR-targeted therapies.
Molecule SMILES: O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Niclosamide is used for the treatment of most tapeworm infections. Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases. Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals.
Molecule SMILES: CC=C1NC(=O)C(CC)NC(=O)CNC(=O)C(C)(C(C)=O)NC(=O)C(Cc2c[nH]c3ccc(O)c(OC)c23)NC(=O)c2csc(n2)C(C)NC(=O)CN(C)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Zelkovamycin C is a natural product found in Kitasatospora with data available.