IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COc1cc(O)c2c(c1)C(=O)c1cc(C)c(O)c(-c3c(OC)cc4c(c3O)C(=O)c3cc(O)c(C)cc3C4=O)c1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Alterporriol Q is a natural product found in Alternaria and Stemphylium with data available.
Molecule SMILES: CSc1[nH]c2cc(Br)cc(Br)c2c1-c1c(Br)[nH]c2cc(Br)cc(Br)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2,4,4',6,6'-Pentabromo-2'-(methylthio)-3,3'-bi[1H-indole] is a natural product found in Laurencia brongniartii with data available.
Molecule SMILES: CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nnnn2-c2ccc(C)cc2)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2,4-dimethyl-5-[2-[[1-(4-methylphenyl)-5-tetrazolyl]thio]-1-oxoethyl]-1H-pyrrole-3-carboxylic acid ethyl ester is a member of tetrazoles.
Molecule SMILES: C=C1CCC2C(C)(C(=O)O)CCCC2(C)C1CCc1ccoc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (1S,4aR,5S)-5-(2-(furan-3-yl)ethyl)-1,4a-dimethyl-6-methylenedecahydronaphthalene-1-carboxylic acid is a natural product found in Pinus sibirica, Pinus pumila, and Pinus armandii with data available.
Molecule SMILES: COc1ccc(CCOC2OC(COC3OCC(O)C(O)C3O)C(OC(=O)C=Cc3ccc(O)c(OC)c3)C(OC3OC(C)C(O)C(O)C3O)C2O)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Angroside C is a natural product found in Scrophularia ningpoensis with data available.
Molecule SMILES: CCCCCCC=CCCCC(=O)CCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 7-Keto-11c-octadecenoic acid is a natural product found in Gardenia resinifera with data available.
Molecule SMILES: CCN(CC)CCOC1CCC2(C)C(=CCC3C4CCC(=O)C4(C)CCC32)C1.Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride is a hydrochloride obtained by reaction of 3beta-(2-diethylaminoethoxy)androst-5-en-17-one with one equivalent of hydrochloric acid. It is a cholesterol synthesis and transport inhibitor. It has a role as an EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor, a nicotinic antagonist, a sterol biosynthesis inhibitor, an antiviral agent and a Hedgehog signaling pathway inhibitor. It contains a 3beta-(2-diethylaminoethoxy)androst-5-en-17-one(1+).
Molecule SMILES: CC1C(O)C(O)C(OC(=O)c2ccccc2)C2(C)C(OC(=O)C=Cc3ccccc3)CC3CC12OC3(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(1S,2R,3R,4R,5R,6R,7S,9R)-3,4-dihydroxy-2,6,10,10-tetramethyl-7-[(E)-3-phenylprop-2-enoyl]oxy-11-oxatricyclo[7.2.1.01,6]dodecan-5-yl] benzoate is a natural product found in Zinowiewia costaricensis with data available.
Molecule SMILES: C=CCc1ccc(O)c(-c2cc(C(O)C(O)CO)ccc2O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: threo-Magnolignn is a natural product found in Magnolia officinalis with data available.
Molecule SMILES: CC1CCCCOC(CN(C)Cc2ccc(Cl)c(Cl)c2)C(C)CN(C(C)CO)C(=O)c2cc(NC(=O)Nc3ccc4c(c3)OCO4)ccc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 1-(1,3-benzodioxol-5-yl)-3-[(3S,9S,10S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-12-[(2R)-1-hydroxypropan-2-yl]-3,10-dimethyl-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]urea is an azamacrocycle and a lactam.
Molecule SMILES: COc1cc(C=CC(=O)OC2C(OC3C(Oc4c(-c5ccc(O)cc5)oc5cc(OC6OC(CO)C(O)C(O)C6O)cc(O)c5c4=O)OC(CO)C(O)C3O)OC(CO)C(O)C2O)cc(OC)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 4',5-Dihydroxy-3-[[2-O-[2-O-[(E)-3-(3,5-dimethoxy-4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]-beta-D-glucopyranosyl]oxy]-7-(beta-D-glucopyranosyloxy)flavone is a natural product found in Brassica napus and Brassica rapa with data available.
Molecule SMILES: CCCCCCCCOO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Octyl hydroperoxide is an alkyl hydroperoxide.
Molecule SMILES: C=C1CCC(Br)C(C)(C)C1OC12OC(C)(C)C(Cl)C=C1C(=O)c1c(O)cc(O)cc1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (3R,10aR)-10a-[(1R,3S)-3-bromo-2,2-dimethyl-6-methylidenecyclohexyl]oxy-3-chloro-6,8-dihydroxy-2,2-dimethyl-3H-benzo[g]chromene-5,10-dione is a natural product found in Streptomyces with data available.
Molecule SMILES: CCC(=O)OC1C(=O)C2(C)C(CCC3C(=C(CCC=C(C)C)C(=O)O)C(OC(C)=O)CC32C)C2(C)CCC(=O)C(C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 6-O-propionyl-6-O-deacetylhelvolic acid is a natural product found in Aspergillus fumigatus with data available.
Molecule SMILES: COc1ccc(O)cc1-c1cc(O)ccc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Versiperol A is a natural product found in Aspergillus versicolor with data available.
Molecule SMILES: OB(O)c1ccc(F)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 4-fluorophenylboronic acid is an organofluorine compound. It is functionally related to a phenylboronic acid.
Molecule SMILES: COC1CC(OC2C(O)CC(OC3C(C)OC(OC4C(C)OC(OC5C(C)OC(OC6CCC7(C)C(=CCC89OC(C)C%10CCC(=O)C%10(C)C(CC87)O9)C6)CC5OC)CC4OC)CC3OC)OC2C)OC(C)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (1S,6S,9R,10R,12R,13S,17R,18S)-6-[(2R,4S,5R,6R)-5-[(2S,4R,5R,6R)-5-[(2S,4R,5R,6R)-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4R,5R,6R)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-9,13,18-trimethyl-19,20-dioxapentacyclo[10.7.1.01,10.04,9.013,17]icos-3-en-14-one is a natural product found in Asclepias tuberosa with data available.
Molecule SMILES: CC=CCCc1c(C)cc2c(C)coc2c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3,5-Dimethyl-6-[(E)-3-pentenyl]-7-methoxybenzofuran is a natural product found in Ligularia virgaurea with data available.
Molecule SMILES: CC(C)C(NC(=O)c1ccc(O)cc1)C(=O)NC(C(=O)NC(C=O)CCCN=C(N)N)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Tokaramide A is a natural product found in Theonella mirabilis with data available.
Molecule SMILES: CC(=O)OC1CCC2(C)C(CCC3Cc4c([nH]c5ccccc45)C32C)C1(C)CCC(O)C(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Penijanthine D is a natural product found in Penicillium janthinellum, Penicillium ianthinellum, and Penicillium simplicissimum with data available.
Molecule SMILES: CCCCCCCCCCCCCCC=COCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: PC(P-16:0/16:0) is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: CSCCC(NC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(=O)NC(C(=O)NC=C1CC(O)C(n2ccc(=O)[nH]c2=O)O1)C(C)N(C)C(=O)C1Cc2cc(O)ccc2CN1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Sansanmycin N is a natural product found in Streptomyces with data available.
Molecule SMILES: CC(C)=CCc1cc(C(=O)C=C(O)c2ccc(O)cc2)c(O)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-[2,4-Dihydroxy-5-(3-methylbut-2-enyl)phenyl]-3-hydroxy-3-(4-hydroxyphenyl)prop-2-en-1-one is a natural product found in Glycyrrhiza echinata with data available.
Molecule SMILES: CC1=CC2C(C(C)(C)O)CCC(C)(O)C2CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (1R,4S,4aR,8aS)-4-(2-hydroxypropan-2-yl)-1,6-dimethyl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol is a natural product found in Streptomyces with data available.
Molecule SMILES: COc1cc(OC)c(OC)c(C)c1C#CC1(C)OC(=O)OC1(C)C#Cc1c(OC)cc(OC)c(OC)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Antrodioxolanone is a natural product found in Taiwanofungus camphoratus with data available.
Molecule SMILES: CC(CCC1(O)OC2CC3C4CC=C5CC(OC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6O)CCC5(C)C4CC(=O)C3(C)C2C1C)COC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1R,2S,4S,6S,7S,8R,9S,12S,13R,16S)-16-[(2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-hydroxy-7,9,13-trimethyl-6-[(3S)-3-methyl-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-10-one is a natural product found in Polygonatum kingianum with data available.
Molecule SMILES: COc1nn(C(=O)[N-]S(=O)(=O)c2ccccc2OC(F)(F)F)c(=O)n1C.[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Flucarbazone-sodium is an organic sodium salt resulting from the formal reaction of the sulfonamide amino group of flucarbazone with 1 mol eq. of sodium hydride. An acetolactate synthase inhibitor, it is used as a herbicide to control grass weeds in cereal crops. Not approved for use within the European Union. It has a role as an EC 2.2.1.6 (acetolactate synthase) inhibitor, a herbicide and an agrochemical. It contains a flucarbazone(1-).
Molecule SMILES: NCCCN(CCCCNC(=O)C=Cc1ccc(O)cc1)C(=O)C=Cc1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: N-[4-[3-aminopropyl-[3-(4-hydroxyphenyl)prop-2-enoyl]amino]butyl]-3-(4-hydroxyphenyl)prop-2-enamide is a natural product found in Aphelandra tetragona with data available.
Molecule SMILES: COc1cc2ccccc2cc1C(=O)OCC(=O)N1CCOCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 3-methoxy-2-naphthalenecarboxylic acid [2-(4-morpholinyl)-2-oxoethyl] ester is a naphthoic acid.
Molecule SMILES: COc1c(O)c(CC=C(C)CCC=C(C)C)cc(-c2coc3cc(O)cc(O)c3c2=O)c1CC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3-[5-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxy-3-methoxy-2-(3-methylbut-2-enyl)phenyl]-5,7-dihydroxychromen-4-one is a natural product found in Millettia pachycarpa with data available.
Molecule SMILES: CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3CCC(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)C(C)(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[12-hydroxy-4,4,8,14-tetramethyl-17-[6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-1,2,3,5,6,7,9,10,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol is a natural product found in Gynostemma pentaphyllum with data available.
Molecule SMILES: COC1C(O)C2=CCN3Cc4cc5c(cc4C(C1O)C23)OCO5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Ungiminorine is a natural product found in Pancratium canariense, Sternbergia sicula, and other organisms with data available.
Molecule SMILES: O=C(O)c1cc2oc3c(Oc4ccc(-c5ccc(O)c(O)c5)cc4O)cc(O)cc3c2cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2,8-Dihydroxy-6-[2-hydroxy-4-(3,4-dihydroxyphenyl)phenoxy]dibenzofuran-3-carboxylic acid is a natural product found in Cladophora socialis with data available.
Molecule SMILES: CC1CC=C(C(C)C2CCC3C4CC(O)C5CC(OC6OC(CO)C(O)C(O)C6O)CCC5(C)C4CCC23C)NC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2R,3R,4S,5S,6R)-2-[[(3S,5S,6R,8S,9S,10R,13S,14R,17R)-6-hydroxy-10,13-dimethyl-17-[(1S)-1-[(3R)-3-methyl-1,2,3,4-tetrahydropyridin-6-yl]ethyl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a natural product found in Cardiocrinum cordatum with data available.
Molecule SMILES: CC(=CC(=O)O)CCC1C(C)=CC(=O)C2C(C)(C)CCCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Callilongisin D is a natural product found in Callicarpa longissima with data available.
Molecule SMILES: O=C(O)C1=CC(O)C(O)C(OC(=O)C2C(c3ccc(O)c(O)c3)Oc3cc(O)cc4c3C2C(O)C(c2ccc(O)c(O)c2)O4)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Brainicin is a natural product found in Brainea insignis with data available.
Molecule SMILES: COc1cc(O)cc(C)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1,4-Dihydroxy-2-methoxy-6-methylbenzene is a natural product found in Taiwanofungus camphoratus, Antrodia cinnamomea, and other organisms with data available.
Molecule SMILES: Oc1ccccc1C1COc2ccccc2C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (4R)-4,2'-Dihydroxyisoflavan is a member of hydroxyisoflavans.
Molecule SMILES: C=CC(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2S)-but-3-en-2-ol is a natural product found in Chaerophyllum hirsutum, Angelica biserrata, and other organisms with data available.
Molecule SMILES: CC(N)C(O)c1ccc(O)c(O)c1.Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Levonordefrin Hydrochloride is the hydrochloride salt of levonordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction.
Molecule SMILES: Cc1c(C)c(Br)c(Br)c(Br)c1Br

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 3,4,5,6-tetrabromo-o-xylene is an off-white solid. (NTP, 1992)
Molecule SMILES: O=C(NCCSCc1ncc(C(F)(F)F)cc1Cl)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N1-[2-({[3-chloro-5-(trifluoromethyl)-2-pyridyl]methyl}thio)ethyl]benzamide is a member of benzamides.
Molecule SMILES: CCOC(=O)Cn1nc(C(F)(F)F)cc1-c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Rovazolac is under investigation in clinical trial NCT03175354 (A Study in Subjects With Moderate Atopic Dermatitis).
Molecule SMILES: CC(CCC=CC(=O)Nc1ccc(C(=O)[O-])cc1)OC1OC(C)C(O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Ascr#8(1-) is conjugate base of ascr#8 It is a conjugate base of an ascr#8.
Molecule SMILES: Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Rimonabant is a carbohydrazide obtained by formal condensation of the carboxy group of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. It is a potent and selective cannabinoid receptor 1 (CB1R) antagonist. Besides its antagonistic properties, numerous studies have shown that, at micromolar concentrations rimonabant behaves as an inverse agonist at CB1 receptors. The drug was the first selective CB1 antagonist/inverse agonist introduced into clinical practice to treat obesity and metabolic-related disorders. It was later withdrawn from market due to CNS-related adverse effects including depression and suicidal ideation. It has a role as an anti-obesity agent, a CB1 receptor antagonist and an appetite depressant. It is a member of pyrazoles, a dichlorobenzene, a carbohydrazide, an amidopiperidine and a member of monochlorobenzenes.
Molecule SMILES: Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil. It was rejected for approval for use in the United States. This decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression.
Molecule SMILES: C=C1COC2(OC3CC4C5CC=C6CC(O)CC(OC7OCC(O)C(OC8OCC(O)C(O)C8O)C7OC7OC(C)C(OC(C)=O)C(O)C7O)C6(C)C5CCC4(C)C3C2C)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [4,5-Dihydroxy-6-[5-hydroxy-4-(3,4,5-trihydroxyoxan-2-yl)oxy-2-(3',4',16-trihydroxy-7,9,13-trimethyl-5'-methylidenespiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14-yl)oxyoxan-3-yl]oxy-2-methyloxan-3-yl] acetate is a natural product found in Sansevieria trifasciata with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)CCCn2nncc2COC1CN(C)Cc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-9-[[methyl-(phenylmethyl)amino]methyl]-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one is a lactam and an azamacrocycle.
Molecule SMILES: CCC(CCC(C)C1CCC2C3CCC4CC(OC5OC(CO)C(O)C(O)C5O)CCC4(C)C3CCC12C)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 5alpha-Stigmastane-3beta-yl beta-D-glucopyranoside is a natural product found in Lepisanthes rubiginosa and Trifolium resupinatum with data available.
Molecule SMILES: CC=C(CCC(C)C1CC=C2C3=C(CCC21C)C1(C)CCC(OC(C)=O)C(C)C1CC3)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(3S,4S,5S,10S,13R,17R)-4,10,13-trimethyl-17-[(Z,2R)-5-propan-2-ylhept-5-en-2-yl]-2,3,4,5,6,7,11,12,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate is a natural product found in Baccharoides anthelmintica with data available.