IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(C)=CCCC(C)=CCCC(C)=CCc1c(O)cc(C)c(C(=O)O)c1[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Ilicicolinate B is a dihydroxybenzoate and a terpenoid.
Molecule SMILES: COC(=O)C1(C)CCC2(C)CCC3(C)C4C=Cc5c(cc6c(c5C)OC5c7c(cc(O)c(O)c7C)C7(C)CCC8(C)C9CC(C)(C(=O)OC)CCC9(C)CCC8(C)C7C5O6)C4(C)CCC3(C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: dimethyl (3S,4R,5R,8S,11R,13R,14S,17R,24R,31R,32R,35S,38R,40R,41S,44R)-20,21-dihydroxy-5,8,11,14,17,22,27,32,35,38,41,44-dodecamethyl-2,25-dioxaundecacyclo[24.20.0.03,24.04,17.05,14.08,13.018,23.028,45.031,44.032,41.035,40]hexatetraconta-1(26),18,20,22,27,29,45-heptaene-11,38-dicarboxylate is a natural product found in Monteverdia ilicifolia with data available.
Molecule SMILES: CC1OC(Oc2cc(O)c3c(=O)c(OC4OCC(O)C(O)C4OC4OC(COC(=O)C=Cc5ccc(O)c(O)c5)C(O)C(O)C4O)c(-c4ccc(O)c(O)c4)oc3c2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(2R,3S,4S,5R,6S)-6-[(2S,3S,4S,5S)-2-[2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate is a natural product found in Oxytropis myriophylla with data available.
Molecule SMILES: CC1=CC(OC=C2C(=O)OC3C2C=C2CCCC(C)(C)C23O)OC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (3E,3aR,8bS)-8a-hydroxy-8,8-dimethyl-3-[[(2R)-4-methyl-5-oxo-2H-furan-2-yl]oxymethylidene]-5,6,7,8b-tetrahydro-3aH-indeno[1,2-b]furan-2-one is a natural product found in Trifolium pratense with data available.
Molecule SMILES: C=C(CO)C12OC1C1(C)C(C)CCCC1CC2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Peribysin A is a natural product found in Periconia with data available.
Molecule SMILES: CC(C)=CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(=O)CCC45CC35CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Cycloartenone is a natural product found in Artemisia diffusa, Gardenia grievei, and other organisms with data available.
Molecule SMILES: C=C1CCC=CC(=O)C(C)C=CC(O)C(C(C)C=CCCC)OC(=O)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Amphidinolide S is a natural product found in Amphidinium with data available.
Molecule SMILES: CCC(C)C1NC(=O)c2nc(oc2C)C(C)NC(=O)c2csc(n2)C(Cc2cncn2C)NC(=O)c2csc1n2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Microcyclamide is a natural product found in Microcystis aeruginosa with data available.
Molecule SMILES: C#CC(O)COc1ccc(CO)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Terricolyne is a natural product found in Neurospora terricola with data available.
Molecule SMILES: O=c1c2c([nH]c3ccccc13)CNC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 1,2,3,4-Tetrahydro-9h-pyrrolo[3,4-b]quinolin-9-one is a natural product found in Peganum harmala with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)c2cc(C#CCc3ccccc3)cnc2OC1CN(C)C(=O)C1CCOCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: N-[[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-(3-phenylprop-1-ynyl)-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-2-yl]methyl]-N-methyl-4-oxanecarboxamide is an aromatic ether.
Molecule SMILES: OCc1cccs1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-thiophenemethanol is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: CC1=CC2c3c(O)cc(C=Cc4ccc(O)cc4O)cc3OC3(c4ccc(O)c5c4OC(C)(C)C=C5)Oc4cc(O)ccc4C(C1)C23

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Sorocein A is a natural product found in Sorocea guilleminiana, Sorocea bonplandii, and Sorocea hilarii with data available.
Molecule SMILES: CNCCCC(=O)c1ccc(=O)[nH]c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2,6-dihydroxypseudooxynicotine is a dihydroxypyridine that is pseudooxynicotine in which the hydrogens at positions 2 and 6 on the pyridine ring are substituted by hydroxy groups. It is a dihydroxypyridine, a secondary amino compound and an aromatic ketone. It is functionally related to a pseudooxynicotine. It is a conjugate base of a 2,6-dihydroxypseudooxynicotinium(1+).
Molecule SMILES: C=CC1C(OC2OC(CO)C(O)C(O)C2O)OC=C(C(=O)O)C1C=Cc1cc(C(=O)[O-])c[n+](CCO)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 5-[(E)-2-[(2S,3R,4S)-5-carboxy-3-ethenyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-4-yl]ethenyl]-1-(2-hydroxyethyl)pyridin-1-ium-3-carboxylate is a natural product found in Lonicera japonica with data available.
Molecule SMILES: C=C1c2ccoc2CC2C1CCC1(O)C(C)(C)CC(OC(C)=O)C(OC(C)=O)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (1-Acetyloxy-4a-hydroxy-4,4,11b-trimethyl-7-methylidene-1,2,3,5,6,6a,11,11a-octahydronaphtho[2,1-f][1]benzofuran-2-yl) acetate is a natural product found in Guilandina bonduc with data available.
Molecule SMILES: CC(=O)OC1(C)CCC23CC1C(C)(C)C2CCC3C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Acetic acid cedrol ester is a natural product found in Artemisia argyi with data available.
Molecule SMILES: Cn1c(=O)c2cn(-c3cccc4ccccc34)cc2n(C)c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1,3-dimethyl-6-(1-naphthalenyl)pyrrolo[3,4-d]pyrimidine-2,4-dione is a member of naphthalenes.
Molecule SMILES: CC(C)(ON=C(C(=O)NC1CN(C(=O)NS(=O)(=O)N2CCN(NC(=O)c3cc(=O)c([O-])c[nH]3)C2=O)C1=O)c1csc(N)n1)C(=O)[O-].[Na+].[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Pirazmonam Sodium is the sodium salt form of pirazmonam, a monocyclic beta-lactam antibiotic. Pirazmonam is more active than aztreonam against nonfermentative gram-negative bacteria.
Molecule SMILES: Nc1[nH]c(=S)ncc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 5-fluoro-2-thiocytosine is a member of pyrimidines and an organohalogen compound.
Molecule SMILES: CC(=O)OC1CCC2(C)C(CCC(C)C23Cc2c(O)cc(CO)c(C=O)c2O3)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Stachybotrysin B is a natural product found in Stachybotrys chartarum with data available.
Molecule SMILES: CCCCCCCCCCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCC)COP(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: PA(15:0/17:0) is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: O=C(OC1C(c2ccc(O)c(O)c2)Oc2c(c(O)cc(O)c2C2c3c(O)cc(O)cc3OC(c3ccc(O)c(O)c3)C2OC(=O)c2cc(O)c(O)c(O)c2)C1c1c(O)cc(O)cc1O)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: [(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R,4S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-4-(2,4,6-trihydroxyphenyl)-3,4-dihydro-2H-chromen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate is a natural product found in Psidium guajava with data available.
Molecule SMILES: Cc1c(O)cc2c(c1O)C(=O)OC2(C)C(=O)C(C)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Phomone B is a natural product found in Phoma with data available.
Molecule SMILES: CC=C(NC(=O)CC(O)CCCCCCCCCCC)C(=O)NC1C(=O)NC(C(C)O)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(=CC)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)N(C)C(C(C)OC2OC(CO)C(O)C(O)C2O)C(=O)NC(Cc2cnc[nH]2)C(=O)OC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (3R)-N-[(E)-1-[[(3S,6S,12R,15E,18R,21R,24S,25R)-12-(3-amino-3-oxopropyl)-15-ethylidene-21-[(1R)-1-hydroxyethyl]-18-[(4-hydroxyphenyl)methyl]-3-(1H-imidazol-5-ylmethyl)-7,25-dimethyl-2,5,8,11,14,17,20,23-octaoxo-6-[(1S)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethyl]-1-oxa-4,7,10,13,16,19,22-heptazacyclopentacos-24-yl]amino]-1-oxobut-2-en-2-yl]-3-hydroxytetradecanamide is a natural product found in Aeromonas with data available.
Molecule SMILES: CC1COC2(CC1O)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(OC7OC(C)C(O)C(O)C7O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2R,3S,4R,5R,6S)-2-[(2S,3S,4R,5S,6S)-3-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,4'S,5'S,6S,7S,8R,9R,12S,13R,16S)-4'-hydroxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-4-yl]oxy-6-methyloxane-3,4,5-triol is a natural product found in Tacca chantrieri with data available.
Molecule SMILES: O=C(O)C=Cc1ccc([O-])c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Cis-caffeate is the conjugate base of cis-caffeic acid; major species at pH 7.3. It is a conjugate base of a cis-caffeic acid.
Molecule SMILES: CC=CC=CC(=O)c1ccc(O)c(C)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-(2,4-Dihydroxy-3-methylphenyl)hexa-2,4-dien-1-one is a natural product found in Trichoderma with data available.
Molecule SMILES: CCC(C)C1NC(=O)C(Cc2ccccc2)NC(=O)CNC(=O)CC(C(=O)NC(C(=O)NC(Cc2ccccc2)C(=O)NCC(=O)NC(Cc2cnc[nH]2)C(=O)NC(Cc2ccc(O)cc2)C(=O)NCC(=O)NCC(=O)O)C(C)CC)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)CNC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N(1)Gly-Phe-Ile-Gly-Trp-Gly-Lys-Asp(1)-Ile-Phe-Gly-His-Tyr-Gly-Gly-OH is a natural product found in Streptomyces with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(OC2OC(COC3OC(COC4OC(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4NC(C)=O)C(O)C(O)C3OC3OC(CO)C(OC4OC(COC5(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O5)C(O)C(O)C4O)C(O)C3NC(C)=O)C(O)C(OC3OC(CO)C(OC4OC(CO)C(OC5OC(COC6(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O6)C(O)C(O)C5O)C(O)C4NC(C)=O)C(O)C3OC3OC(CO)C(OC4OC(COC5(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O5)C(O)C(O)C4O)C(O)C3NC(C)=O)C2O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: CID 91851863 is a polysaccharide.
Molecule SMILES: CC(=O)OC1CC(=O)C(C)(C)C2CCC34OC3C3=C(C)C(=O)OC3CC4C12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Gelomulide F is a natural product found in Suregada multiflora with data available.
Molecule SMILES: CCCC(=O)Nc1ncnc2c1ncn2C1OC2COP(=O)(O)OC2C1OC(=O)CCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Butanoic acid [(4aS,6S,7S,7aS)-2-hydroxy-2-oxo-6-[6-(1-oxobutylamino)-9-purinyl]-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-7-yl] ester is a 3',5'-cyclic purine nucleotide.
Molecule SMILES: CC(C)(O)C1OC(C)(C2CCC3(C)C2C(O)CC2C4(C)CCC(OC5OC(CO)C(O)C(O)C5OC5OCC(O)C(O)C5O)C(C)(C)C4CCC23C)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (20S,23S,24S)-3beta-(2-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyloxy)-20,24-epoxy-5alpha-dammarane-12beta,23,25-triol is a natural product found in Gynostemma pentaphyllum with data available.
Molecule SMILES: c1ccc(-c2nnc(SCC3CCCO3)nc2-c2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 3-(2-oxolanylmethylthio)-5,6-diphenyl-1,2,4-triazine is an aryl sulfide.
Molecule SMILES: OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Ido(b1-2b)D-Sorf is a natural product found in Psidium guajava, Pteris multifida, and other organisms with data available.
Molecule SMILES: C=CC(C)(C)c1c2c(c(O)c3ccc(=O)oc13)C(=O)CC(C)(C)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Clausenidin is a natural product found in Clausena excavata with data available.
Molecule SMILES: C=CC(C)(O)CCC1C(=C)CCC(Br)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: beta-Snyderol is a natural product found in Laurencia obtusa and Laurencia dendroidea with data available.
Molecule SMILES: CN1C2CCC1CC(OC(=O)C(O)Cc1ccccc1)C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (R)-(-)-Littorine is a natural product found in Anthocercis ilicifolia, Duboisia leichhardtii, and other organisms with data available.
Molecule SMILES: CC(=O)OC(C)C(C=CC(O)C(O)C1OC(=O)C=CC1OC(C)=O)OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: [(2S,3S)-2-[(E,1S,2R,5S,6S)-5,6-diacetyloxy-1,2-dihydroxyhept-3-enyl]-6-oxo-2,3-dihydropyran-3-yl] acetate is a natural product found in Syncolostemon argenteus with data available.
Molecule SMILES: OCC1OC(n2cnc3c2NC=NCC3O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2'-Deoxycoformycin is a natural product found in Aspergillus nidulans with data available.
Molecule SMILES: C[S+](CCC(=O)C(=O)O)CC1OC(n2cnc3c(N)ncnc32)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: S-adenosyl-4-methylthio-2-oxobutanoic acid is a sulfonium compound comprising 4-methylthio-2-oxobutanoic acid having an adenosin-5'-yl group attached to the sulfur. It has a role as an Escherichia coli metabolite. It is a sulfonium compound and an organic cation. It is functionally related to a 4-methylthio-2-oxobutanoic acid. It is a conjugate acid of a S-adenosyl-4-methylthio-2-oxobutanoate.
Molecule SMILES: C[S+](CCC(=O)C(=O)O)CC1OC(n2cnc3c(N)ncnc32)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: S-Adenosyl-4-methylthio-2-oxobutanoate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: C[S+](CCC(=O)C(=O)O)CC1OC(n2cnc3c(N)ncnc32)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: S-adenosyl-4-methylthio-2-oxobutanoic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: C=C1C(=O)OC2CC(C)C3C=CC(=O)C3(C)C(O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Helenalin extract is a natural product found in Hymenoxys, Helenium autumnale, and other organisms with data available.
Molecule SMILES: O=[AsH](O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Arsonic acid is a member of arsonic acids. It is a conjugate acid of an arsonate(1-).
Molecule SMILES: Cl.NC(N)=NC(=O)c1nc(Cl)c(N)nc1N.O.O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Amiloride hydrochloride dihydrate is a hydrate that is the dihydrate of amiloride hydrochloride. It has a role as a diuretic and a sodium channel blocker. It contains an amiloride hydrochloride.
Molecule SMILES: Cl.NC(N)=NC(=O)c1nc(Cl)c(N)nc1N.O.O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Amiloride Hydrochloride is the hydrochloride salt of amiloride, a synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and collecting ducts of the kidney, thereby preventing the absorption of sodium and increasing its excretion along with water, to produce naturesis. In response to the hypernatremic conditions in the kidney, the plasma membrane becomes hyperpolarized and electrochemical forces are reduced, which then prevents the excretion of potassium and hydrogen into the lumen.
Molecule SMILES: CC(C)C(=O)CCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 24-oxocholest-5-en-3beta-ol is a bile acid.
Molecule SMILES: CC(C)C(=O)CCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 24-Ketocholesterol is a natural product found in Sargassum fusiforme, Eisenia bicyclis, and Durvillaea potatorum with data available.
Molecule SMILES: N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Pentamidine is a potent, broad spectrum antiinfective agent with activity against several parasitic worms, protozoa and fungi that has been used mainly in the treatment and the prophylaxis of Pneumocystis jiroveci (formerly carinii) infection in immunocompromised persons. Pentamidine is relatively toxic and therapy requires careful monitoring. Pentamidine has been associated with transient serum aminotransferase elevations during therapy and with rare instances of clinically apparent liver injury.
Molecule SMILES: N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Pentamidine is a diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. It has a role as a trypanocidal drug, an antifungal agent, a NMDA receptor antagonist, an anti-inflammatory agent, a chemokine receptor 5 antagonist, an EC 2.3.1.48 (histone acetyltransferase) inhibitor, a calmodulin antagonist, a S100 calcium-binding protein B inhibitor and a xenobiotic. It is a carboxamidine, a diether and an aromatic ether. It is a conjugate base of a pentamidinium(2+).
Molecule SMILES: N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.