IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CCOC(=O)OOC(=O)OCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: This liquid peroxide is particularly sensitive to temperature rises and contamination. Above a given "Control Temperature" they decompose violently. It is generally stored or transported in a solvent slurry, water, alcohol, etc.
Molecule SMILES: C=C(C)C1CC(CC2(CC=C(C)C)C(=O)C3=C(OC(C)C(C)C3=O)C(C(CC(=O)O)c3ccccc3)=C2O)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Isobrasiliensophyllic acid A is a natural product found in Calophyllum brasiliense with data available.
Molecule SMILES: CC(=CC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 23-methyl-ergosta-5,22E-dien-3beta-ol is a natural product found in Petrosia weinbergi, Pyrocystis lunula, and other organisms with data available.
Molecule SMILES: COc1cc(C2Oc3c(OC)cc(CCCO)cc3C2CO)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 3-[2alpha-(3-Methoxy-4-hydroxyphenyl)-3alpha-(hydroxymethyl)-7-methoxycoumaran-5-yl]-1-propanol is a natural product found in Mitragyna inermis and Rosa multiflora with data available.
Molecule SMILES: CC(=O)NC(CO)C(O)C(OC1OC(CO)C(OC2OC(COC3OC(CO)C(O)C(O)C3OC3OC(CO)C(OC4OC(CO)C(O)C(OC5(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O5)C4O)C(O)C3NC(C)=O)C(O)C(OC3OC(COC4OC(CO)C(OC5OC(CO)C(O)C(OC6(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O6)C5O)C(O)C4NC(C)=O)C(O)C(O)C3OC3OC(CO)C(OC4OC(CO)C(O)C(OC5(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O5)C4O)C(O)C3NC(C)=O)C2O)C(O)C1NC(C)=O)C(O)COC1OC(C)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: CID 91849326 is a polysaccharide.
Molecule SMILES: COC1C=CC23c4cc5c(cc4CN(CC2O)C3C1)OCO5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (1R,13R,15R,18R)-15-methoxy-5,7-dioxa-12-azapentacyclo[10.5.2.01,13.02,10.04,8]nonadeca-2,4(8),9,16-tetraen-18-ol is a natural product found in Crinum asiaticum with data available.
Molecule SMILES: CC1CCC(C(C)C)C(OC(=O)c2ccccc2O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Menthyl salicylate is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.
Molecule SMILES: CC1CCC(C(C)C)C(OC(=O)c2ccccc2O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Menthyl salicylate is an ester of menthol and salicylic acid.  This product is used to treat minor aches and pains of the muscles/joints (e.g., arthritis, backache, sprains).
Molecule SMILES: CC1CCC2(OC1)OC1CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C1C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (1S,2S,4R,5'R,6R,7R,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol is a natural product found in Dioscorea tokoro with data available.
Molecule SMILES: CC1=C2N=C(C=C3N=C(C(C)=C4[N-]C(C)(C5N=C1C(C)(CCC(=O)NCC(C)OP(=O)([O-])OC1C(CO)OC(n6cnc7cc(C)c(C)cc76)C1O)C5CC(N)=O)C(C)(CC(N)=O)C4CCC(N)=O)C(C)(CC(N)=O)C3CCC(N)=O)C(C)(C)C2CCC(N)=O.[CH3-].[Co+3]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Mecobalamin is a synthetic and active form of vitamin B12 that can cross the blood brain barrier without biotransformation, that may be used to treat or prevent vitamin B12 deficiency and its complications. Upon administration, mecobalamin is able to replace endogenous vitamin B12, increase vitamin B12 levels and improve vitamin B12 deficiency. Vitamin B12 is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. It improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. Its metabolism is interconnected with that of folic acid.
Molecule SMILES: CCCC=C(C)CCCC(COC1OC(CO)C(O)C(O)C1O)NC(=O)C(O)C(O)C=CCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (E)-2,3-dihydroxy-N-[(E,2R)-6-methyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxydec-6-en-2-yl]undec-4-enamide is a natural product found in Penicillium with data available.
Molecule SMILES: CC1CC(O)C(O)CO1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: ophiocerin C is a natural product found in Ophioceras venezuelense with data available.
Molecule SMILES: CC=C1NC(=O)C(C(C)C)NC(=O)C(O)C(C(C)CCCCCCCCCC(Cl)CC)NC(=O)C2CCCN2C(=O)C(CC(N)=O)N(C)C(=O)C(C(C)OC)NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(C(C)O)NC(=O)C(C(C)O)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3-[3-(2-Amino-2-oxoethyl)-28-(12-chlorotetradecan-2-yl)-21-ethylidene-27-hydroxy-15,18-bis(1-hydroxyethyl)-6-(1-methoxyethyl)-4-methyl-2,5,8,11,14,17,20,23,26,30-decaoxo-24-propan-2-yl-1,4,7,10,13,16,19,22,25,29-decazabicyclo[29.3.0]tetratriacontan-12-yl]propanamide is a natural product found in Romanoa with data available.
Molecule SMILES: COC1CC(OC2CC3=CCC4C(=O)C(c5ccoc5C)CCC4C3(C)CC2O)OC(C)C1OC1CC(O)C(OC2CC(OC)C(OC3OC(CO)C(O)C(O)C3O)C(C)O2)C(C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2R,4aS,4bR,6R,7R,10aR)-6-hydroxy-7-[(2R,4R,5S,6S)-5-[(2S,4S,5S,6R)-4-hydroxy-5-[(2S,4R,5S,6S)-4-methoxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4b-methyl-2-(2-methylfuran-3-yl)-2,3,4,4a,5,6,7,8,10,10a-decahydrophenanthren-1-one is a natural product found in Cynanchum ascyrifolium with data available.
Molecule SMILES: COC(=O)C1(C)CCC2(C(=O)OC3OC(CO)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(C(=O)O)C(O)C(OC7OCC(O)C(O)C7O)C6O)C(C)(C)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8aR,11R,12aS,14aR,14bR)-11-methoxycarbonyl-4,4,6a,6b,11,14b-hexamethyl-8a-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxane-2-carboxylic acid is a natural product found in Chenopodium quinoa with data available.
Molecule SMILES: COC1CC(OC2C(C)OC3(COC4CC(OC(C)C5(O)CCC6C7CC=C8CC(O)CCC8(C)C7CCC65C)OC(C)C4OO3)CC2OC)OC(C)C1OC1CC(OC)C(OC2CC(OC)C(OC3OC(C)C(O)C(OC)C3OC(C)=O)C(C)O2)C(C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Periplocoside E is a natural product found in Periploca sepium and Periploca forrestii with data available.
Molecule SMILES: CCC(C)C(O)(C(=O)OCC1CC[N+]2([O-])CCCC12)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Curassavine N-oxide is a natural product found in Heliotropium curassavicum with data available.
Molecule SMILES: CC1OC(OC2C(OC3=CC4C(=CCC5C4(C)C(=O)CC4(C)CC(=O)CC54C)C(C)(C)C3=O)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (8S,9R,10R,13S,14S)-2-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4,4,9,13,14-pentamethyl-7,8,10,12,15,17-hexahydrocyclopenta[a]phenanthrene-3,11,16-trione is a natural product found in Trichosanthes tricuspidata with data available.
Molecule SMILES: CCCCCCCCCC=CC#CC=COCC(O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (2S)-3-[(1Z,5Z)-pentadeca-1,5-dien-3-ynoxy]propane-1,2-diol is a natural product found in Raspailia ramosa with data available.
Molecule SMILES: CC1=C(CCC(C)COC2OC(CO)C(O)C(O)C2O)OC2CC3C4CC=C5CC(OS(=O)(=O)O)CC(OC6OC(C)C(O)C(O)C6O)C5(C)C4CCC3(C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(1S,2S,4S,8S,9S,12S,13R,14R,16R)-7,9,13-trimethyl-6-[3-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-14-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,18-dien-16-yl] hydrogen sulfate is a natural product found in Nolina microcarpa with data available.
Molecule SMILES: CC(C)C1C=CC(O)C2C3C(C)(O)C(O)CC(Br)C3(C)CCC12CBr

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 12S-hydroxybromosphaerodiol is a natural product found in Sphaerococcus coronopifolius with data available.
Molecule SMILES: O=C(NC(CSSCC(NC(=O)c1coc(-c2nc3ccccc3cc2O)n1)C(=O)O)C(=O)O)c1coc(-c2nc3ccccc3cc2O)n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (2R)-3-[[(2R)-2-carboxy-2-[[2-(3-hydroxyquinolin-2-yl)-1,3-oxazole-4-carbonyl]amino]ethyl]disulfanyl]-2-[[2-(3-hydroxyquinolin-2-yl)-1,3-oxazole-4-carbonyl]amino]propanoic acid is a natural product found in Streptomyces cyaneofuscatus with data available.
Molecule SMILES: COc1cc(O)c(O)c2c1C(O)Oc1c(O)cc(C(C)=O)c(O)c1-2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Alternethanoxin D is a natural product found in Alternaria sonchi with data available.
Molecule SMILES: C=C(C(=O)O)C(CCCCCC(=O)OCC)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (R)-2-Methylene-3-(hydroxycarbonyl)nonanedioic acid 9-ethyl ester is a natural product found in Aspergillus niger with data available.
Molecule SMILES: CC=CC=CC(=O)c1cc(C(=O)O)c(OC)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Scalbucillin A is a natural product found in Scytalidium album with data available.
Molecule SMILES: CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(COS(=O)(=O)O)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 10-Hydroxy-2,2,6a,6b,9,12a-hexamethyl-9-(sulfooxymethyl)-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid is a natural product found in Gomphrena macrocephala with data available.
Molecule SMILES: Cc1nc(-c2ccccc2)sc1C(=O)C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1cccnc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 4-hydroxy-3-(4-methyl-2-phenyl-1,3-thiazole-5-carbonyl)-1-(3-morpholin-4-ylpropyl)-2-pyridin-3-yl-2H-pyrrol-5-one is a natural product found in Perilla frutescens with data available.
Molecule SMILES: CCC1(O)C(=O)OCC2=CCN3CCC(OC(=O)C(C(C)C)C1O)C23

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Axillaridine is a natural product found in Crotalaria scassellatii with data available.
Molecule SMILES: CC(C)(COP(=O)([O-])OP(=O)([O-])OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)([O-])[O-])C(O)C(=O)NCCC(=O)NCCSC(=O)C=CCCCCC(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Trans-2-octenedioyl-CoA(5-) is an acyl-CoA oxoanion that is the pentaanion of trans-2-octenedioyl-CoA, arising from deprotonation of phosphate, diphosphate and carboxylic acid functions; major species at pH 7.3. It is a conjugate base of a trans-2-octenedioyl-CoA.
Molecule SMILES: C1=CC=CC=CC=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Cyclooctatetraene appears as a colorless liquid. May irritate skin and eyes. Less dense than water and insoluble in water. Vapors heavier than air. Used to make rubber.
Molecule SMILES: C1=CC=CC=CC=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [8]annulene is an antiaromatic annulene that is cyclooctane having four double bonds at positions 1, 3, 5 and 7.
Molecule SMILES: O=C([O-])CCC=CCC=CCC=CCC=CCC=CCC=CCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoate is a polyunsaturated fatty acid anion that is the conjugate base of (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. It is a hydroxy polyunsaturated fatty acid anion and an omega-hydroxy-long-chain fatty acid anion. It is a conjugate base of a (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid.
Molecule SMILES: CC(=O)OC1C(C)C=CC(C)(C)C(=O)CC(OC(=O)c2cccnc2)C(C)=CC2C(OC(=O)c3ccccc3)C(C)CC21OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: [(1S,2S,3aR,4R,5R,6E,11R,12E,13aS)-3a,4-diacetyloxy-1-benzoyloxy-2,5,8,8,12-pentamethyl-9-oxo-1,2,3,4,5,10,11,13a-octahydrocyclopenta[12]annulen-11-yl] pyridine-3-carboxylate is a natural product found in Euphorbia helioscopia with data available.
Molecule SMILES: Cc1c(O)cc(O)cc1C(C)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 5-[(2S,3R)-3-hydroxybutan-2-yl]-4-methylbenzene-1,3-diol is a natural product found in Penicillium citrinum with data available.
Molecule SMILES: COC(=O)CC1C(C(C)=O)CC2OC(=O)C(OC(=O)C=C(C)C(C)(C)O)C3C4(C(=O)OC)OCC23C1C(O)C4O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: CID 6439339 is a natural product found in Brucea antidysenterica with data available.
Molecule SMILES: C=C1C(O)CCC2(C)C1CC(O)C1=C3C(O)CC(C(C)CCC(CC)C(C)C)C3(C)CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 17-(5-Ethyl-6-methylheptan-2-yl)-10,13-dimethyl-4-methylidene-1,2,3,5,6,7,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthrene-3,7,15-triol is a natural product found in Theonella swinhoei with data available.
Molecule SMILES: COC(=O)C12Oc3cc(C)cc(O)c3C(=O)C1=CC=CC2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: methyl 4,8-dihydroxy-6-methyl-9-oxo-4H-xanthene-4a-carboxylate is a natural product found in Aspergillus latus and Aspergillus quadrilineatus with data available.
Molecule SMILES: NCCCCNC(=O)C(CCCN(O)C=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CCC[N+]([O-])=Cc1csc(-c2ccccc2O)n1)NC=O)C(O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Malleonitrone is a natural product found in Burkholderia thailandensis with data available.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Nicardipine is a second generation calcium channel blocker used in the treatment of hypertension and stable angina pectoris. Nicardipene therapy has been associated with a low rate of transient serum enzyme elevations, but has not been linked convincingly to instances of clinically apparent liver injury with jaundice.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Nicardipine is a racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension. It has a role as an antihypertensive agent, a calcium channel blocker, a vasodilator agent and an autophagy inhibitor. It contains a (S)-nicardipine and a (R)-nicardipine.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Nicardipine is a Dihydropyridine Calcium Channel Blocker. The mechanism of action of nicardipine is as a Calcium Channel Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Cytochrome P450 2C19 Inhibitor.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Nicardipine is a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.
Molecule SMILES: C=CCCC(=O)OCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Ethyl 4-pentenoate is a fatty acid ester.
Molecule SMILES: CN(C)CC(=O)Nc1ccc2c(c1)C1CC(CC(=O)NCc3ccncc3)OC(CO)C1O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-[(1R,3R,4aR,9aS)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(pyridin-4-ylmethyl)acetamide is an amino acid amide.
Molecule SMILES: COc1ccc2c(c1OC)C(=O)OC2C1c2c(cc3c(c2OC)OCO3)CCN1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one is a member of isoquinolines.
Molecule SMILES: COc1ccc2c(c1OC)C(=O)OC2C1c2c(cc3c(c2OC)OCO3)CCN1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: beta-Narcotine is a natural product found in Corydalis heterocarpa var. japonica, Corydalis ochotensis, and Corydalis ophiocarpa with data available.
Molecule SMILES: C=CC(C)(C)c1[nH]c2c(CC=C(C)C)cccc2c1C=C1NC(=O)C(C)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (+)-variecolorin G is a natural product found in Aspergillus with data available.
Molecule SMILES: CN(C)N=Nc1nc[nH]c1C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Dacarbazine appears as white to ivory microcrystals or off-white crystalline solid. (NTP, 1992)
Molecule SMILES: CN(C)N=Nc1nc[nH]c1C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Dacarbazine (also known as DTIC) is an intravenously administered alkylating agent used in the therapy of Hodgkin disease and malignant melanoma. Dacarbazine therapy has been associated with serum enzyme elevations during therapy and occasional cases of severe and distinctive acute hepatic failure, probably caused by acute sinusoidal obstruction syndrome.
Molecule SMILES: CN(C)N=Nc1nc[nH]c1C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.