IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC1CN(C(C)CO)C(=O)Cc2cc(NC(=O)Nc3ccccc3)ccc2OC1CN(C)Cc1ccncc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 1-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(pyridin-4-ylmethyl)amino]methyl]-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]-3-phenylurea is a member of ureas.
Molecule SMILES: O=C(Nc1cccc(Oc2ccc3c(c2)C(=O)NC3=O)c1)c1ccco1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-[3-[(1,3-dioxo-5-isoindolyl)oxy]phenyl]-2-furancarboxamide is a member of furans and an aromatic amide.
Molecule SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1C(=O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Desoximetasone is dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis. It has a role as an anti-inflammatory drug and an antipruritic drug. It is an 11beta-hydroxy steroid, a 21-hydroxy steroid, a glucocorticoid, a 20-oxo steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a primary alpha-hydroxy ketone.
Molecule SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1C(=O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Molecule SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1C(=O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Desoximetasone is a Corticosteroid. The mechanism of action of desoximetasone is as a Corticosteroid Hormone Receptor Agonist.
Molecule SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1C(=O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Desoximetasone is a synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity. Desoximetasone activates specific intracellular receptors, which bind to distinct sites on DNA to modify gene transcription. This results in an induction of the synthesis of anti-inflammatory proteins and suppression of the synthesis of inflammatory mediators. This leads to an overall reduction in chronic inflammation and autoimmune reactions. Desoximetasone is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Molecule SMILES: CCCCCCCCCCCCCCCc1cc(C(C)CCCCCCCCCCCCCc2cccc(OC)c2OC)cc(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 5-[(2R)-15-(2,3-dimethoxyphenyl)pentadecan-2-yl]-1,2-dimethoxy-3-pentadecylbenzene is a natural product found in Toxicodendron vernicifluum with data available.
Molecule SMILES: CC1=C(C(=O)O)CC2C1(C)CCC(C)C2(C)CCC(C)CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (3aR,6R,7S,7aR)-7-[(3S)-4-carboxy-3-methylbutyl]-3,3a,6,7-tetramethyl-4,5,6,7a-tetrahydro-1H-indene-2-carboxylic acid is a natural product found in Clausena dunniana and Clausena anisata with data available.
Molecule SMILES: COC(=O)c1cc(C(=O)OC)cc(N2C(=O)CC(NNC(=O)c3ccc(C)cc3)C2=O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 5-[3-[[(4-methylphenyl)-oxomethyl]hydrazo]-2,5-dioxo-1-pyrrolidinyl]benzene-1,3-dicarboxylic acid dimethyl ester is an amidobenzoic acid.
Molecule SMILES: CC(=O)OC1CC2C(C=C(C)CCC=C1C)OC(=O)C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Herbolide A is a natural product found in Artemisia vallesiaca, Artemisia herba-alba, and Artemisia fragrans with data available.
Molecule SMILES: CC(C)C(NC(=O)C(O)C(N)CCCCCCCCl)C(=O)N(C)C(C(=O)N(C)C(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccc(O)cc1)C(=O)O)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Microginin 299A is a natural product found in Cyanobacterium and Microcystis aeruginosa with data available.
Molecule SMILES: C=C(C(C)C)C(O)C(OC(C)=O)C(C)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(O)C(C)(C)C1CC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(2S,3S,4R)-4-hydroxy-2-[(3S,5R,10S,13R,14R,17S)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptan-3-yl] acetate is a natural product found in Pisolithus tinctorius and Pisolithus arhizus with data available.
Molecule SMILES: Cc1cc(CC2OC(CO)C(OC(=O)c3ccccc3)C(O)C2O)cc(O)c1C(=O)c1cc(O)cc(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(2R,3S,4R,5R)-6-[[4-(3,5-dihydroxybenzoyl)-3-hydroxy-5-methylphenyl]methyl]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl] benzoate is a natural product found in Hypericum humifusum with data available.
Molecule SMILES: O=C([O-])C=CCl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-chloroacrylate is a monocarboxylic acid anion that results from the removal of a proton from the carboxylic acid group of 3-chloroacrylic acid. It is a conjugate base of a 3-chloroacrylic acid.
Molecule SMILES: c1ccc2[nH]c(C3CCN(Cc4c[nH]c5ccccc45)C3)nc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-[(3S)-1-(1H-Indol-3-ylmethyl)-3-pyrrolidinyl]-1H-benzimidazole is a member of indoles.
Molecule SMILES: O=C1c2c(OC3OC(CO)C(O)C(O)C3O)cc(O)cc2OC(c2ccc(O)c(O)c2)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S,3R)-2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one is a natural product found in Dillenia pentagyna with data available.
Molecule SMILES: CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)OC(COC=CCCCCCCC=CCCCCCCCC)COP(=O)(O)OCCN

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-(1Z,9Z-octadecadienyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine is a 1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamine in which the alkyl and the acyl groups at positions 1 and 2 are specified as (1Z,9Z)-octadecadienyl and (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl respectively. It has a role as a mouse metabolite. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid.
Molecule SMILES: CC1=C(C)C(=O)C(C)=C(C)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Duroquinone is a member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which all four hydrogens are substituted by methyl groups.
Molecule SMILES: CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Leu-Leu-Gly is a tripeptide composed of two L-leucine units and glycine joined in sequence by peptide linkages. It has a role as a metabolite. It is functionally related to a L-leucine and a glycine.
Molecule SMILES: CCC(C)NCCOCCOc1ccc(Cl)cc1Br

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: N-[2-[2-(2-bromo-4-chlorophenoxy)ethoxy]ethyl]-2-butanamine is an aromatic ether.
Molecule SMILES: NC(Cc1ccc(OP(=O)(O)O)cc1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: O(4)-phospho-D-tyrosine is a D-tyrosine derivative that is D-tyrosine phosphorylated at the phenolic hydroxy group. It is an O(4)-phosphotyrosine, a D-tyrosine derivative, a D-alpha-amino acid and an aromatic amino acid. It is an enantiomer of an O(4)-phospho-L-tyrosine.
Molecule SMILES: CCC(=O)Nc1ccc2c(c1)C(=O)N(C)CC(OC)C(C)CN(Cc1cccnc1)C(C)CO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: N-[(4S,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-(3-pyridinylmethyl)-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide is a lactam and an azamacrocycle.
Molecule SMILES: NC(CCCC=C(CCC(N)C(=O)O)c1c(CCC(N)C(=O)O)cc(CCC(N)C(=O)O)c[n+]1CCCCC(N)C(=O)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Pentasine is an organooxygen compound. It is functionally related to a hexacarboxylic acid.
Molecule SMILES: CCc1c(Cl)c(O)c(Cl)c(O)c1C(=O)OC1C(C)OC(OCC2=CC=CCC(O)C(C)=CC(CC)C(OC3OC(C)(C)C(O)C(O)C3OC(=O)C(C)C)C(C)=CC(C)=CCC(C(C)O)OC2=O)C(OC)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Lipiarmycin B3 is a natural product found in Actinoplanes deccanensis with data available.
Molecule SMILES: OCC1OC(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Alpha-D-ribose is a D-ribofuranose. It is an enantiomer of an alpha-L-ribose.
Molecule SMILES: COC1CC(OC2CCC3(C)C(=CCC4(O)C3CC(OC(=O)C=Cc3ccccc3)C3(C)C(C(C)=O)CCC43O)C2)OC(C)C1OC1CC(OC)C(OC2CC(OC)C(OC3OC(CO)C(OC4OC(CO)C(O)C(O)C4O)C(O)C3O)C(C)O2)C(C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [17-acetyl-3-[5-[5-[5-[3,4-dihydroxy-6-(hydroxymethyl)-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-8,14-dihydroxy-10,13-dimethyl-2,3,4,7,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-12-yl] 3-phenylprop-2-enoate is a natural product found in Asclepias tuberosa with data available.
Molecule SMILES: COC(=O)C1CC23C4=C(CCC41)CCC1CN4CC(C)C(CCC12COC(C)=O)C43O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: methyl (1R,3R,4R,10S,14S,15R,18R,19R)-18-(acetyloxymethyl)-19-hydroxy-14-methyl-12-azahexacyclo[10.6.1.11,4.010,18.015,19.07,20]icos-7(20)-ene-3-carboxylate is a natural product found in Daphniphyllum oldhamii, Daphniphyllum glaucescens, and other organisms with data available.
Molecule SMILES: COc1ccc(C2CCCC(CCc3ccc(O)cc3)O2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Centrolobine is a natural product found in Centrolobium robustum and Centrolobium tomentosum with data available.
Molecule SMILES: CCC(C)C(=O)OC1CC2(C)C(=O)CCC2C2=C1C1(C)C(COC)OC(=O)C3C(O)NC(=O)C31C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Wortmannine B2 is a natural product found in Niesslia with data available.
Molecule SMILES: COC1C(O)C(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)C(O)CC43O)C2)OC(C)C1OC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Neogitostin is a natural product found in Digitalis purpurea with data available.
Molecule SMILES: CCC=CCC=CCC=CCC=CCC=CCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC=CCCCCCCC=CCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: PC(20:5(5Z,8Z,11Z,14Z,17Z)/P-18:1(9Z)) is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: CCCCCCCCCC(=O)CC(=Cc1cc(CCC)ncc1C(=O)OC)C(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Methyl 4-(2-acetyl-4-oxotridec-1-enyl)-6-propylpyridine-3-carboxylate is a natural product found in Monascus pilosus with data available.
Molecule SMILES: COc1ccc(C=Cc2cc(OC)cc(=O)o2)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 10-Methoxyyangonin is an aromatic ether and a member of 2-pyranones.
Molecule SMILES: CS(=O)c1c2nc3ccccc3oc-2cc(=O)c1N

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Questiomycin C is a natural product found in Alteromonas with data available.
Molecule SMILES: CC(C)c1cc2c(c(O)c1O)C1=C(CC2)C(C)(C)CCC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Sageone is a natural product found in Salvia pachyphylla, Salvia, and other organisms with data available.
Molecule SMILES: CC(C)COP(=O)(c1ccc(N(C)C)cc1)C(O)c1ccccc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [[4-(dimethylamino)phenyl]-(2-methylpropoxy)phosphoryl]-(2-fluorophenyl)methanol is a tertiary amino compound and a dialkylarylamine.
Molecule SMILES: CCCc1cc(=O)oc2c3c(c(C(=O)C(C)CC)c(O)c12)OC(C(C)(C)O)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: MAB 4 is a furanocoumarin.
Molecule SMILES: COc1cc2c(cc1O)CN1CCC23C=CC(O)CC13.O=C(O)C(F)(F)F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (+)-8-O-demethylmaritidine Trifluoroacetic acid is an organic molecular entity. It has a role as a metabolite.
Molecule SMILES: COc1cc(C(=O)OC2CC(C)=CC(O)C3(C)CCC(O)(C(C)C)C23)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Kuhistanicaol D is a natural product found in Ferula kuhistanica with data available.
Molecule SMILES: CC1CCC2C(C)(C)C3C4OC4(C)CCC123

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Italicene epoxide is a natural product found in Daucus carota with data available.
Molecule SMILES: CC(C)CC=CC=CC(=O)NC1CCCNC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Ornilactam A is a natural product found in Streptomyces with data available.
Molecule SMILES: CCCCCCCCCCCCCC(C)C(O)C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(O)OP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 2-hydroxy-3-methylhexadecanoyl-CoA is the 2-hydroxy-3-methylhexadecanoyl derivative of coenzyme A. It is functionally related to a 2-hydroxy-3-methylhexadecanoic acid. It is a conjugate acid of a 2-hydroxy-3-methylhexadecanoyl-CoA(4-).
Molecule SMILES: CCC(=O)OC(Cc1ccccc1)(c1ccccc1)C(C)CN(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Propoxyphene is only found in individuals that have used or taken this drug. It is a narcotic analgesic structurally related to methadone. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect. [PubChem]Propoxyphene acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervous system (CNS). Propoxyphene primarily affects OP3 receptors, which are coupled with G-protein receptors and function as modulators, both positive and negative, of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for GDP on the G-protein complex. As the effector system is adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease intracellular cAMP by inhibiting adenylate cyclase. Subsequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Opioids such as propoxyphene also inhibit the release of vasopressin, somatostatin, insulin, and glucagon. Opioids close N-type voltage-operated calcium channels (OP2-receptor agonist) and open calcium-dependent inwardly rectifying potassium channels (OP3 and OP1 receptor agonist). This results in hyperpolarization and reduced neuronal excitability.
Molecule SMILES: CCN1CC2(COC)CCC(OC)C34C5CC6C(O)CC7(OCOC7(C(=O)C23)C14)C5C6OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (1S,2R,3R,4S,5R,6S,8R,12R,13S,16S,19S,20R)-14-ethyl-6-hydroxy-4,19-dimethoxy-16-(methoxymethyl)-9,11-dioxa-14-azaheptacyclo[10.7.2.12,5.01,13.03,8.08,12.016,20]docosan-21-one is a natural product found in Delphinium dyctiocarpum and Delphinium uralense with data available.
Molecule SMILES: C=C(CO)C1Cc2cc(C(C)=O)ccc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2-[(2S)-5-Acetyl-2,3-dihydrobenzofuran-2-yl]allyl alcohol is a natural product found in Helichrysum italicum, Helichrysum stoechas, and Chrysothamnus viscidiflorus with data available.
Molecule SMILES: CC(=O)OC1C(OC(=O)c2cccnc2)CC(C)C23OC(C)(C)C(CC(OC(=O)c4ccccc4)C12C)C3OC(=O)c1cccnc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [5-Acetyloxy-7-benzoyloxy-2,6,10,10-tetramethyl-12-(pyridine-3-carbonyloxy)-11-oxatricyclo[7.2.1.01,6]dodecan-4-yl] pyridine-3-carboxylate is a natural product found in Gymnosporia heterophylla with data available.
Molecule SMILES: C=C(C)C(O)CCC(C)(O)C1CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (20S,24R)-Dammar-25-ene-3alpha,12beta,20,24-tetrol is a natural product found in Betula humilis and Betula fruticosa with data available.
Molecule SMILES: COC1CN(C)C(=O)c2cc(NC(=O)Nc3ccccc3)ccc2OCC(C)NCC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 1-[(4R,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-3-phenylurea is an azamacrocycle and a lactam.
Molecule SMILES: CCCCc1nc(-c2ccc(OCCCN(CC)CC)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Azeliragon has been used in trials studying the treatment of Alzheimer's Disease.
Molecule SMILES: CCCCc1nc(-c2ccc(OCCCN(CC)CC)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Azeliragon is an orally bioavailable inhibitor of the receptor for advanced glycation end-products (RAGE), with potential antineoplastic activity. Upon oral administration, azeliragon targets and binds to RAGE, thereby preventing binding of RAGE ligands to RAGE, and prevents RAGE-mediated signaling, This may inhibit proliferation and induce apoptosis of tumor cells in which the RAGE pathway is overactivated. RAGE, a receptor belonging to the immunoglobulin superfamily, plays a key role in inflammation and is overexpressed in a variety of cancers. It plays a key role in tumor cell proliferation, survival and metastasis.