IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=C1CC23CC1(O)CCC2C12CC=CC(CO)(C(=O)O1)C2C3C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 5-Hydroxy-11-(hydroxymethyl)-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-12-ene-9-carboxylic acid is a natural product found in Canavalia gladiata with data available.
Molecule SMILES: C=C1C=CCC(C)(C)C12CCC(C)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: cis-Vitispirane is a natural product found in Hamamelis virginiana and Baccharis dracunculifolia with data available.
Molecule SMILES: COc1cc2c(O)c3c(c(-c4ccc5c(c4)OCO5)c2cc1O)C(=O)OC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Haplomyrtin is a natural product found in Haplophyllum cappadocicum, Haplophyllum myrtifolium, and other organisms with data available.
Molecule SMILES: CCNC(=O)CC1CCC2C(COCC(O)CN2C(=O)c2ccccn2)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-[(3S,6aR,8R,10aR)-3-hydroxy-1-[oxo(2-pyridinyl)methyl]-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocin-8-yl]-N-ethylacetamide is a pyridinemonocarboxylic acid and an aromatic carboxylic acid.
Molecule SMILES: COC1CN(C)C(=O)c2cc(NS(=O)(=O)c3ccc(Cl)cc3)ccc2OCC(C)N(C)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 4-chloro-N-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzenesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CCc1c(C)cc2c(c1O)C(=O)C1=C(C2=O)C(C)(C)OC1(OC)C(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: methyl (3S)-6-ethyl-5-hydroxy-3-methoxy-1,1,7-trimethyl-4,9-dioxobenzo[f][2]benzofuran-3-carboxylate is a natural product found in Garveia annulata with data available.
Molecule SMILES: CCn1cc(NC(=S)Nc2cc(Cl)ccc2OC)c(C(N)=O)n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 4-[[(5-chloro-2-methoxyanilino)-sulfanylidenemethyl]amino]-1-ethyl-3-pyrazolecarboxamide is a member of thioureas.
Molecule SMILES: CC1CN(C)C2Cc3c[nH]c4cccc(c34)C2C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: fumigaclavine B is a natural product found in Penicillium roqueforti, Aspergillus fumigatus, and Aspergillus sydowii with data available.
Molecule SMILES: CCCCCC(=O)N(C)C(c1ccccc1)C(O)C(=O)OC1CC2(O)C(OC(=O)c3ccccc3)C3C4(OC(C)=O)COC4CC(O)C3(C)C(=O)C(OC(C)=O)C(=C1C)C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(1S,2S,3R,4R,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-[hexanoyl(methyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate is a natural product found in Taxus cuspidata with data available.
Molecule SMILES: Cc1ccc(C(=O)OP(=O)([O-])OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 4-methylbenzoyl-AMP(1-) is an organophosphate oxoanion obtained by deprotonation of the phosphate OH group of 4-methylbenzoyl-AMP; major microspecies at pH 7.3. It is functionally related to an adenosine 5'-monophosphate(2-) and a p-toluate.
Molecule SMILES: O=C(O)CNC(=O)CC(O)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-hydroxyphenylpropionylglycine is a N-acyl-amino acid.
Molecule SMILES: C=CC(C)(CCC=C(C)C(=O)OC1C(C)OC(OC(C)(C=C)CCC=C(C)C(=O)OC2CC3(C(=O)OC4OC(CO)C(O)C(O)C4OC4OC(C)C(O)C(OC5OCC(O)C(O)C5O)C4O)C(O)CC4(C)C(=CCC5C6(C)CCC(OC7OC(COC8OC(C)C(O)C(O)C8OC8OCC(O)C(O)C8O)C(O)C(O)C7OC7OC(CO)C(O)C(O)C7O)C(C)(C)C6CCC54C)C3CC2(C)C)C(O)C1O)OC1OC(C)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: [(2R,3S,4R,5R,6S)-3-[(2R,3S,4R,5S,6R)-3,5-dihydroxy-6-methyl-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] (3S,4aR,5R,6aS,6bR,10S,12aR)-10-[(2R,3R,4S,5S,6R)-6-[[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxymethyl]-4,5-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3-[(2E,6S)-6-[(2S,3R,4R,5S,6R)-5-[(2E,6S)-2,6-dimethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyocta-2,7-dienoyl]oxy-3,4-dihydroxy-6-methyloxan-2-yl]oxy-2,6-dimethylocta-2,7-dienoyl]oxy-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate is a natural product found in Albizia gummifera with data available.
Molecule SMILES: COc1ccc(CC(OC)c2cc(O)c(O)c(OC)c2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 3-methoxy-5-[(1R)-1-methoxy-2-(4-methoxyphenyl)ethyl]benzene-1,2-diol is a natural product found in Dendrobium moniliforme and Dendrobium candidum with data available.
Molecule SMILES: CC(=CCCC(=CC=CC1=CC(=O)OC1)CO)CCC1=C(C)CCCC1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Luffariolide A is a natural product found in Luffariella with data available.
Molecule SMILES: C=CC(C)(C)c1[nH]c2ccc(CC(O)C(C)(C)Cl)cc2c1C=C1NC(=O)C(C)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: variecolorin A is a natural product found in Aspergillus stellatus with data available.
Molecule SMILES: C#CC(O)CCCCCCCCCCC(C)CCCCCCCCCCCCC=CC#CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Aztequynol B is a natural product found in Petrosia with data available.
Molecule SMILES: CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(OC7OC(C)C(OC8OC(CO)C(O)C(O)C8O)C(O)C7O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Diosgenin 3-[glucosyl-(1->4)-rhamnosyl-(1->4)-[rhamnosyl-(1->2)]-glucoside] is a steroid saponin.
Molecule SMILES: CC(C)CC#Cc1ccc2c(c1)OC(CN(C)C(=O)CC1CC1)C(C)CN(C(C)CO)S2(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-cyclopropyl-N-[[(4S,5S)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-8-(4-methylpent-1-ynyl)-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-N-methylacetamide is an aromatic ether.
Molecule SMILES: CC1(C)Oc2cc(-c3cc4ccc(O)cc4o3)cc(O)c2CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 7-(6-Hydroxy-1-benzofuran-2-yl)-2,2-dimethyl-3,4-dihydrochromene-3,5-diol is a natural product found in Morus wittiorum with data available.
Molecule SMILES: CC1(O)C=Cc2c(cc(O)c3c2C(=O)c2cccc(O)c2-3)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Fluostatin K is a natural product found in Micromonospora rosaria with data available.
Molecule SMILES: C=C1CCC2C1C13OCC2(O)C=CC1=C(COC1OC(CO)C(O)C(O)C1O)C(=O)O3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (1R,8S,9S,13S)-8-hydroxy-12-methylidene-4-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-2,14-dioxatetracyclo[6.5.2.01,5.09,13]pentadeca-4,6-dien-3-one is a natural product found in Cichorium endivia with data available.
Molecule SMILES: O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(C3OC(CO)C(O)C(O)C3OC3OC(CO)C(O)C(O)C3O)c(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Glucoisovitexin is a natural product found in Cucumis melo, Cucumis sativus, and other organisms with data available.
Molecule SMILES: COC1=CC(=O)c2c(cc3c(c2O)C(=O)C2(OC4CCC(OC5CCC(O)C(C)O5)C(C)O4)C(O)=C(C(C)=O)C(=O)C(OC4CCC(OC5CCC(OC6CCC(OC7CCC(OC(=O)C(C)(C)C(=O)O)C(C)O7)C(C)O6)C(C)O5)C(C)O4)C2C3)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Cervimycin A is a natural product found in Streptomyces tendae with data available.
Molecule SMILES: CC(=O)C1(O)C(=O)N2C(C)(C)C3Cc4cccc5c4C4(OC1(O)C2(O)C34)C(=O)N5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1R)-5-acetyl-3,4,5-trihydroxy-8,8-dimethyl-19-oxa-7,16-diazahexacyclo[9.6.1.11,4.02,9.03,7.015,18]nonadeca-11(18),12,14-triene-6,17-dione is a natural product found in Penicillium dipodomyicola with data available.
Molecule SMILES: CNC1CCC2(C)C(CCC3C2CCC2(C)C(C(C)=O)CCC32)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-[(3R,5S,8R,9S,10S,13R,14S,17S)-10,13-dimethyl-3-(methylamino)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone is a natural product found in Sarcococca coriacea and Holarrhena pubescens with data available.
Molecule SMILES: CCCC=CC=CCCCCCCCCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 10E,12E-Hexadecadien-1-ol is a long-chain fatty alcohol.
Molecule SMILES: CCCC=CC=CCCCCCCCCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 10,12-Hexadecadien-1-ol is a natural product found in Hemileuca electra with data available.
Molecule SMILES: CC(=O)NC1C(OP(=O)([O-])OP(=O)([O-])OCC2OC(n3ccc(=O)[nH]c3=O)C(O)C2O)OC(C)C(=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose(2-) is a nucleotide-sugar oxoanion arising from deprotonation of the diphosphate OH groups of UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose; major species at pH 7.3. It is a conjugate base of an UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.
Molecule SMILES: C=C1C(=O)OC2C1C(OC(=O)C(C)=CCO)CC1(CO1)C1C(OC(C)=O)C=C(C)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(3aR,4R,6R,6aS,7S,9aR,9bR)-7-acetyloxy-9-methyl-3-methylidene-2-oxospiro[4,5,6a,7,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-6,2'-oxirane]-4-yl] (E)-4-hydroxy-2-methylbut-2-enoate is a natural product found in Eupatorium chinense with data available.
Molecule SMILES: C=CCSS(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: S-2-Propenyl methanesulfinothioate is a sulfur oxoacid derivative.
Molecule SMILES: C=CCSS(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: S-2-Propenyl methanesulfinothioate is a natural product found in Allium, Allium sativum, and Allium ursinum with data available.
Molecule SMILES: COc1cc(CC(O)C(=O)c2cc(CC=C(C)C)c(O)cc2O)cc(CC=C(C)C)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 1-[2,4-dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl]-2-hydroxy-3-[4-hydroxy-3-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]propan-1-one is a member of chalcones.
Molecule SMILES: CC1CN(C(C)CO)C(=O)c2c(c3ccccc3n2C)-c2ccccc2COC1CN(C)Cc1cccc(C(=O)O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: LSM-12775 is an indolyl carboxylic acid.
Molecule SMILES: CC(C)CC1NC(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)NC(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: cyclo[D-Leu-D-N(Me)Leu-D-Leu-D-N(Me)Leu-D-Leu] is a natural product found in Galaxaura filamentosa with data available.
Molecule SMILES: COc1cc2c(O)c(c1)NC(=O)CC(OC)C=CC=CC=CCC(OC(=O)C(C)NC(=O)C1CCCCC1)C(C)C(O)C(C)=CCC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 22-O-methylmycotrieninII is a natural product found in Streptomyces rishiriensis with data available.
Molecule SMILES: O=C1NC(=O)C(c2c[nH]c3cc(Cl)c(Cl)cc23)=C1c1c[nH]c2ccc(Cl)cc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Dionemycin is a natural product found in Streptomyces with data available.
Molecule SMILES: Nc1nc2c(ncn2C2OC(CO)C3OP(=O)([O-])OC32)c(=O)[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2',3'-cyclic GMP(1-) is a 2',3'-cyclic nucleotide(1-) which is obtained from 2',3'-cyclic GMP by removal of a proton from the cyclic phosphate group. It is a conjugate base of a 2',3'-cyclic GMP.
Molecule SMILES: CC(O)C#Cc1ccc(C2C(CO)N3CCCCN(CC4CCOCC4)CC23)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2R)-4-[4-[(8S,9S,10R)-10-(hydroxymethyl)-6-(4-oxanylmethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]-3-butyn-2-ol is a ring assembly, a member of azetidines and a member of benzenes.
Molecule SMILES: O.O.O.[Fe].[Ti]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Ilmenite is a mineral with formula of Fe2+Ti4+O3. The IMA symbol is Ilm.
Molecule SMILES: CC1(C)CCC2(C)CCC3(C)C(=CC(O)C4C5(C)C(O)C(O)C(O)C(C)(C)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Oleana-12-ene-1beta,2alpha,3beta,11alpha-tetrol is a natural product found in Salvia kronenburgii with data available.
Molecule SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(C)CCC1C3(C)CCC(O)CC3=CC(O)C12O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Stylisterol A is an ergostanoid.
Molecule SMILES: Brc1c(NC2=NCCN2)ccc2nccnc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Brimonidine is a quinoxaline derivative, a secondary amine and a member of imidazoles. It has a role as an adrenergic agonist, an antihypertensive agent and an alpha-adrenergic agonist.
Molecule SMILES: Brc1c(NC2=NCCN2)ccc2nccnc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than [clonidine] or [apraclonidine], which are also alpha-2 adrenergic agonists. Alpha-2 adrenergic agonists are members of the ocular hypotensive agent drug class that are used in the chronic treatment of glaucoma. Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular pressure, is critical since glaucoma is considered to be a common cause of blindness worldwide.   Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. Because it is oxidately stable, brimonidine is associated with fewer reports of ocular allergic reactions compared to other alpha-2 adrenergic agonists. The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan and brimonidine is the only selective alpha-adrenergic receptor agonist approved for chronic treatment in glaucoma. Brimonidine is also found in ophthalmic solutions in combination with [brinzolamide] under the market name Simbrinza for the reduction in intraocular pressure. Unlike nonselective beta-blockers used in ocular hypertension, brimonidine is not associated with significantly adverse cardiopulmonary side effects. Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease. The topical form of brimonidine was approved by the FDA in August 2013 for the symptomatic treatment of persistent facial erythema of rosacea in adults. It is marketed under the brand name Mirvaso. Brimonidine is the first topical treatment approved for facial erythema of rosacea.
Molecule SMILES: Brc1c(NC2=NCCN2)ccc2nccnc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Brimonidine is an alpha-Adrenergic Agonist. The mechanism of action of brimonidine is as an Adrenergic alpha-Agonist.
Molecule SMILES: Brc1c(NC2=NCCN2)ccc2nccnc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Brimonidine is an imidazole derivative and a selective alpha-2 adrenergic receptor agonist. Upon ocular administration, brimonidine acts on the blood vessels causing them to constrict which leads to a decrease in the production of aqueous humor. Brimonidine also enhances the uveoscleral outflow of aqueous humor. This reduces intraocular pressure.
Molecule SMILES: Brc1c(NC2=NCCN2)ccc2nccnc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Brimonidine is only found in individuals that have used or taken this drug. It is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis. [Wikipedia] A topical gel formulation, marketed under the name Mirvaso, was FDA approved on August 2013 for the treatment of rosacea. Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric studies in animals and humans suggest that Brimonidine has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.
Molecule SMILES: COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3cccc4c(=O)c5cccc(OC)c5[nH]c34)cc1)CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Elacridar (GW120918) is an oral bioenhancer that targets multiple drug resistance in tumors. In many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline. Development is assumed to have been discontinued.
Molecule SMILES: CC1CN(C(C)CO)C(=O)c2cc(NC(=O)CCCN(C)C)ccc2OC1CN(C)Cc1ccc(C(=O)O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 4-[[[(2R,3R)-8-[[4-(dimethylamino)-1-oxobutyl]amino]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid is a member of benzoic acids.
Molecule SMILES: OC1CCC(O)C23OC12C(O)C1OC1C31Oc2cccc3cccc(c23)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Palmarumycin C16 is a natural product found in Coniothyrium with data available.