IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COc1ccc(C(C)(C)C)cc1CNC1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
Molecule SMILES: COC(=O)c1sc(-c2ccc(C(C)(C)C)cc2)cc1NC(=O)CSCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-[[2-[[5-(4-tert-butylphenyl)-2-methoxycarbonyl-3-thiophenyl]amino]-2-oxoethyl]thio]acetic acid is an alkylbenzene.
Molecule SMILES: CCC=C1C=CC(=O)C(O)C12C(=O)N(OC)C(C)(O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Triticone E is a natural product found in Drechslera and Pyrenophora tritici-repentis with data available.
Molecule SMILES: CSC=CC(=O)NCCOC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: cis-Entadamide A beta-D-glucopyranoside is a natural product found in Entada rheedei with data available.
Molecule SMILES: C=CC(C)c1ccc(C)cc1CC(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 1-[2-[(2R)-but-3-en-2-yl]-5-methylphenyl]-2-methylpropan-2-ol is a natural product found in Commiphora myrrha with data available.
Molecule SMILES: NC(=O)Cc1ccc(OS(=O)(=O)O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Benzeneacetamide-4-O-sulphate is a sulfuric ester.
Molecule SMILES: COC1CC(OC2C(C)OC(OC3C(C)OC(OC4C(C)OC(OC5C(C)OC(OC6CCC7(C)C(=CCC8C7CC(O)C7(C)C(C(C)=O)CCC87O)C6)CC5OC)CC4OC)CC3OC)CC2OC)OC(C)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 1-[(3S,8R,9S,10R,12R,13S,14S,17R)-12,14-dihydroxy-3-[(2R,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4R,5S,6S)-5-[(2S,4S,5R,6R)-5-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]ethanone is a natural product found in Cynanchum rostellatum with data available.
Molecule SMILES: CCCCCCCCCCCCC(O)C1CCC(C(O)CCCCCCC(=O)CCCC(O)CC2=CC(C)OC2=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2S)-4-[(2R,13S)-2,13-dihydroxy-13-[(2R,5S)-5-[(1R)-1-hydroxytridecyl]oxolan-2-yl]-6-oxotridecyl]-2-methyl-2H-furan-5-one is a natural product found in Annona montana with data available.
Molecule SMILES: COc1c2c(c3c(c1CCC(=O)O)OC(C)(C)C=C3)OC(C)(C)C=C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Eriostemoic acid is a natural product found in Geijera paniculata, Geleznowia verrucosa, and Philotheca thryptomenoides with data available.
Molecule SMILES: CC(=O)OC1CC2(C)C(CCC3C4(C)CCC(O)C(C)C4C(O)C(O)C32C)C1=C(CCC=C(C)C)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (2Z)-2-[(3R,4S,5S,6R,7R,8S,9S,10R,13R,14S,16S)-16-acetyloxy-3,6,7-trihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid is a natural product found in Sarocladium strictum with data available.
Molecule SMILES: CC(=CC1C(C(C)=CCC(O)CC(O)CC(O)C(C)C(O)C(C)C)C=CC2(C)C(O)CCC(C)C12)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (E)-3-[(1S,2R,4aS,5R,8S,8aR)-5-hydroxy-4a,8-dimethyl-2-[(E,5S,7R,9R,10S,11S)-5,7,9,11-tetrahydroxy-10,12-dimethyltridec-2-en-2-yl]-2,5,6,7,8,8a-hexahydro-1H-naphthalen-1-yl]-2-methylprop-2-enoic acid is a natural product found in Streptomyces with data available.
Molecule SMILES: O=P(O)(O)C(Cc1ccccn1)P(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Piridronic Acid is a synthetic pyridinyl bisphosphonate with anti-resorptive activity. Although the exact mechanism of action has yet to be fully elucidated, piridronic acid likely binds to hydroxyapatite crystals in the bone matrix and inhibits farnesyl pyrophosphate synthase, an enzyme that plays an important role in the mevalonate pathway. This inhibits the formation of isoprenoid metabolites that are substrates for protein prenylation. This prevents farnesylation and geranylgeranylation of proteins essential for osteoclast function, leading to the induction of apoptosis and eventually, osteoclast-cell death. By preventing osteoclast-mediated bone resorption, piridronic acid decreases bone turnover and stabilizes the bone matrix.
Molecule SMILES: CC(=O)OC1CCC2=CCCC(C)C2(C)C=C(C)C1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Paralemnolin E is a natural product found in Paralemnalia thyrsoides with data available.
Molecule SMILES: CC(=O)c1csc(-c2ccc(C(F)(F)F)cc2)n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-{2-[4-(Trifluoromethyl)phenyl]-1,3-thiazol-4-yl}ethan-1-one is a member of (trifluoromethyl)benzenes.
Molecule SMILES: CCCCCC=CCCC(=O)CCCCCCCCCCCCCCCCCC(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Methyl 19-oxooctacos-22-enoate is a natural product found in Cuspidaria convoluta with data available.
Molecule SMILES: Cc1cccc(-c2ccc(C3C(CO)N4C(=O)CN(S(=O)(=O)c5cccc(F)c5)CC34)cc2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (6R,7R,8S)-4-(3-fluorophenyl)sulfonyl-8-(hydroxymethyl)-7-[4-(3-methylphenyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one is a member of biphenyls.
Molecule SMILES: C=C1CCC(OC(C)=O)C2(C)C(OC(C)=O)CC(OC(C)=O)C3(CO3)C2C(OC(C)=O)C2(O)C(C)C(=O)OC2C1Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [(1S,2R,3R,4R,7S,8S,12R,13R,14S,16R,17R)-2,14,16-triacetyloxy-8-chloro-3-hydroxy-4,13-dimethyl-9-methylidene-5-oxospiro[6-oxatricyclo[11.4.0.03,7]heptadecane-17,2'-oxirane]-12-yl] acetate is a natural product found in Junceella juncea and Ellisella with data available.
Molecule SMILES: COc1ccccc1C=CC(=O)c1cc(Br)ccc1OC(=O)c1ccco1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 4-Bromo-2-[3-(2-methoxyphenyl)acryloyl]phenyl 2-furoate is an aromatic compound. It has a role as an anticoronaviral agent.
Molecule SMILES: CCC(=O)N1C(CO)C(c2ccccc2)C1CN(C(C)C)S(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: N-[[(2S,3S,4S)-4-(hydroxymethyl)-1-(1-oxopropyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylmethanesulfonamide is a member of azetidines, a ring assembly and a member of benzenes.
Molecule SMILES: CC(=O)NC1c2nc(CC(=O)O)cn2C(CO)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (5R,6R,7S,8S)-5-(Hydroxymethyl)-6,7-dihydroxy-8-(acetylamino)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-acetic acid is a natural product found in Streptomyces amakusaensis with data available.
Molecule SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: OOB-PA is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: COC(=O)CC1CC2c3cc(NC(=O)Nc4ccccc4F)ccc3OC2C(CO)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2-[(1R,3R,4aR,9aS)-6-[[(2-fluoroanilino)-oxomethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]acetic acid methyl ester is a member of ureas.
Molecule SMILES: CCCCCCCCCCCCC(O)C1CCC(C(O)CCCC(=O)CCCCCCCCC2=CC(C)(O)OC2=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (5R)-5-hydroxy-3-[(13R)-13-hydroxy-13-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]oxolan-2-yl]-9-oxotridecyl]-5-methylfuran-2-one is a natural product found in Annona cherimola with data available.
Molecule SMILES: CC1=CC(O)C(O)C2(C)C1C(O)C(=O)C1(C)C3C(=O)OC(C3C)C(O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1,4abeta,7alpha,8abeta-Tetramethyl-3alpha,4beta,5beta,10alpha-tetrahydroxy-6alpha,8alpha-(epoxymethano)-3,4,4a,4balpha,5,6,7,8,8a,9,10,10aalpha-dodecahydrophenanthrene-9,11-dione is a natural product found in Eurycoma longifolia with data available.
Molecule SMILES: CC=CC=CCCC=CC=CC(=O)NCC(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: dodeca-2E,4E,8Z,10Z-tetraenoic acid isobutylamide is a natural product found in Echinacea angustifolia, Asarum heterotropoides, and other organisms with data available.
Molecule SMILES: COC(=O)C(C)=C1C(=O)C(O)C2(C)C3=C(CC4C5(OC(=O)C(CO)=C5CC5C(O)(COC(=O)C(C)=CCO)C6CC6C54C)C13)C1CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(1R,2S,8R,9S,10S,12R,13S,14S,17S,19R,20S,21R,23Z)-9,21-dihydroxy-5-(hydroxymethyl)-23-(1-methoxy-1-oxopropan-2-ylidene)-13,20-dimethyl-4,22-dioxo-3-oxaoctacyclo[14.7.1.02,6.02,14.08,13.010,12.017,19.020,24]tetracosa-5,16(24)-dien-9-yl]methyl (E)-4-hydroxy-2-methylbut-2-enoate is a natural product found in Sarcandra glabra with data available.
Molecule SMILES: C=CC(C)(C)c1cc2cc(OC)c(OC)cc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Rutacultin is a member of coumarins.
Molecule SMILES: C=CC(C)(C)c1cc2cc(OC)c(OC)cc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Rutacultin is a natural product found in Helietta apiculata and Ruta chalepensis with data available.
Molecule SMILES: O=C1C2CC(CN3CCCCC23)C2CCCCN12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (-)-Deoxylupanoline is a natural product found in Hesperolaburnum platycarpum with data available.
Molecule SMILES: CC1C(=O)OC2C1CCC1(C)C(=O)C=CC(C)(O)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 4-Epipallensin is a natural product found in Artemisia pallens with data available.
Molecule SMILES: COc1ccc(CC2NC(=O)C=CCC(C(C)C3OC3c3ccccc3)OC(=O)C(CC(C)C)OC(=O)C(C)CNC2=O)cc1Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Cryptophycin is the cryptophycins are a family of 16-membered macrolide antimitotic agents isolated from the cyanobacteria Nostoc sp. The mechanism of anticancer activity of the cryptophycins has been associated with their destabilization of microtubules and induction of bcl-2 phosphorylation leading to apoptosis. Cryptophycins demonstrated activity against the wide spectrum of solid tumors including those that overexpress the multidrug resistance efflux pump P-glycoprotein. (NCI)
Molecule SMILES: CC(C)c1cc2c(cc1O)C1(C)CCCC(C)(C)C1CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Abieta-9(11),8(14),12-trien-12-ol is a natural product found in Juniperus drupacea, Cupressus sempervirens, and other organisms with data available.
Molecule SMILES: CCCCCCCCC(C)=CCc1oc(C(C)=O)c(C)c(=O)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2-acetyl-3,5-dimethyl-6-[(E)-3-methylundec-2-enyl]pyran-4-one is a natural product found in Verticillium with data available.
Molecule SMILES: CC#CC#CCCC=CC(=O)NCCc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Deca-2z-en-6,8-diynoic acid phenethylamide is a natural product found in Spilanthes, Acmella oleracea, and Salmea scandens with data available.
Molecule SMILES: O=C(OC1OC2COC(=O)c3cc(O)c(O)c(O)c3-c3c(cc(O)c(O)c3O)C(=O)OC3C2OC(=O)C24CC5(O)OCC(O)C5OC2C(O)(O)C(O)(O)C2(O)Oc5c(O)c(O)cc(c5C42)C(=O)OC13)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Macabarterin is a ellagitannin isolated from the stem bark of Macaranga barteri and has been shown to exhibit anti-inflammatory activity. It has a role as a metabolite and an anti-inflammatory agent. It is an ellagitannin and a gallate ester.
Molecule SMILES: O=C(OC1OC2COC(=O)c3cc(O)c(O)c(O)c3-c3c(cc(O)c(O)c3O)C(=O)OC3C2OC(=O)C24CC5(O)OCC(O)C5OC2C(O)(O)C(O)(O)C2(O)Oc5c(O)c(O)cc(c5C42)C(=O)OC13)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Macabarterin is a natural product found in Macaranga barteri with data available.
Molecule SMILES: CC1=CC2=C(CC(C)(C)C2O)C(C)CCC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (3S,4Z,6S,9R)-2,2,5,9-tetramethyl-1,3,6,7,8,9-hexahydrocyclopenta[8]annulene-3,6-diol is a natural product found in Sinularia capillosa with data available.
Molecule SMILES: CC1C(=O)C2=C(CC(C)(CO)C2)C(C)(O)C12CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2S,5R,7R)-7-hydroxy-2-(hydroxymethyl)-2,5,7-trimethylspiro[3,5-dihydro-1H-indene-6,1'-cyclopropane]-4-one is a natural product found in Coprinopsis episcopalis with data available.
Molecule SMILES: CC(C)CCCC(C)(O)c1ccc(COC(=O)c2ccc(C(C)(O)CCCC(C)C)c(O)c2)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Peniciaculin B is a natural product found in Talaromyces aculeatus with data available.
Molecule SMILES: CC1OC(OC2CCC3(C)C(C2)CC2OC24C3CC(O)C2(C)C(C3=CC(=O)OC3)CCC24O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Aspecioside is a cardenolide glycoside.
Molecule SMILES: CC1OC(OC2CCC3(C)C(C2)CC2OC24C3CC(O)C2(C)C(C3=CC(=O)OC3)CCC24O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Aspecioside is a natural product found in Asclepias syriaca and Asclepias speciosa with data available.
Molecule SMILES: CC1(O)C=CC2=CC(=O)OCC2C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Cladosporactone A is a natural product found in Cladosporium cladosporioides with data available.
Molecule SMILES: COC1CN(C)C(=O)c2ccc(NS(=O)(=O)CC(F)(F)F)cc2OCC(C)N(Cc2ccccn2)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2,2,2-trifluoro-N-[(5S,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(2-pyridinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]ethanesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CSCCC(NC(=O)C(CS)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(N)CC(C)C)C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Nangibotide is under investigation in clinical trial NCT04055909 (Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock).
Molecule SMILES: CSCCC(NC(=O)C(CS)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(N)CC(C)C)C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Nangibotide is a synthetic and inhibitory triggering receptor expressed on myeloid cells-1 (TREM-1) peptide, with potential anti-inflammatory and immunomodulatory activities. Upon administration, nangibotide binds to TREM-1 ligand and inhibits the binding of the TREM-1 ligand to TREM-1. This blocks the TREM-1-mediated amplification of innate immunity signaling, and prevents the production of pro-inflammatory mediators and inflammation. TREM-1, an immune-receptor expressed in neutrophils, mature monocytes, macrophages, natural killer (NK) cells and endothelial cells, is up-regulated following Toll-Like Receptors (TLR) or NOD-like receptors (NLR) signaling. It plays a key role in the amplification of inflammatory and innate immune responses.
Molecule SMILES: CC1CCCCOC(CN(C)Cc2ccccc2)C(C)CN(C(C)CO)C(=O)c2cc(NS(C)(=O)=O)ccc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: N-[(3S,9R,10R)-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-9-[[methyl-(phenylmethyl)amino]methyl]-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]methanesulfonamide is an azamacrocycle and a lactam.
Molecule SMILES: C=CCc1cc2c(cc1OC)OC(C1C34CC(C(C)(C)O)C1(CC=C)C(=O)C=C3OCO4)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Bicycloillicinone asarone acetal is a natural product found in Illicium tashiroi with data available.
Molecule SMILES: C=C(C=CC=C(COC(C)=O)C1CCC2(C(CCCO)C(=C(C)C=O)CCC2(C)O)C1O)CCC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(2E,4E)-2-[(3S,4S,5S,6R,7Z,10S)-4,10-dihydroxy-6-(3-hydroxypropyl)-10-methyl-7-(1-oxopropan-2-ylidene)spiro[4.5]decan-3-yl]-10-methyl-6-methylideneundeca-2,4,9-trienyl] acetate is a natural product found in Iris japonica and Iris domestica with data available.
Molecule SMILES: Cc1c(O)c2cc(O)c(C=O)cc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 4,6-Dihydroxy-7-formyl-3-methylcoumarin is a natural product found in Pestalotiopsis versicolor with data available.
Molecule SMILES: CC(C)CC(NC(=O)C1CCCN1)C(=O)NCC(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Melanostatin is a natural product found in Streptomyces clavifer with data available.
Molecule SMILES: O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)c(-c3c(O)cc(O)c4c(=O)c(O)c(-c5ccc(O)c(O)c5)oc34)c(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-(3,4-Dihydroxyphenyl)-8-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxochromen-6-yl]-3,5,7-trihydroxychromen-4-one is a natural product found in Hypericum perforatum with data available.
Molecule SMILES: COc1ccccc1C#Cc1cnc2c(c1)C(=O)N(C(C)CO)CC(C)C(CN(C)S(=O)(=O)c1cn(C)cn1)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: N-[[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-8-[2-(2-methoxyphenyl)ethynyl]-3-methyl-6-oxo-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide is a member of methoxybenzenes.