IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CCC(CCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (3R,8S,9R,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol is a natural product found in Asparagus officinalis with data available.
Molecule SMILES: CCCCCCC=CCCCCCCCCC=COC(COC(=O)CCCCCCCC=CCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: PC(16:1(9Z)/P-18:1(11Z)) is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: COC1CCC2(C)C3CCC45OC4(CCC4C(C)(C)C(O)CCC45C)CC3(C)CCC2C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 13beta,14beta-Epoxy-3beta-methoxyserrtan-21beta-ol is a natural product found in Picea jezoensis with data available.
Molecule SMILES: C=C(C)C(O)COc1ccc(C(O)CNC(=O)C=Cc2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-[(2R)-2-hydroxy-2-[4-[(2S)-2-hydroxy-3-methylbut-3-enoxy]phenyl]ethyl]-3-phenylprop-2-enamide is a natural product found in Aegle marmelos with data available.
Molecule SMILES: CCCC(O)C1=C(C)C(=O)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3-(1-Hydroxybutyl)-2,4-dimethylcyclopent-2-en-1-one is a natural product found in Diaporthe with data available.
Molecule SMILES: CC(C)(C)c1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Glybuthiazol is a sulfonamide and a member of benzenes.
Molecule SMILES: CC(C)(C)c1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Glybuthiazol is a sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glybuthiazol is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.
Molecule SMILES: COc1ccc(-c2coc3cc(O)ccc3c2=O)c([O-])c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2'-hydroxyformononetin(1-) is a flavonoid oxoanion that is the conjugate base of 2'-hydroxyformononetin, obtained by deprotonation of the 7-hydroxy group. Major microspecies at pH 7.3 (according to Marvin v 6.2.0.). It is a conjugate base of a 2'-hydroxyformononetin.
Molecule SMILES: C=CC(=C)CCC1C(=C)CCC2C(C)(C)CCCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (4aS,8R,8aS)-4,4,8a-trimethyl-7-methylidene-8-(3-methylidenepent-4-enyl)-2,3,4a,5,6,8-hexahydro-1H-naphthalene is a natural product found in Halocarpus bidwillii, Thujopsis dolabrata, and other organisms with data available.
Molecule SMILES: CCOC1OC(=O)CC1C1CCC2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (21R)-3-Oxo-21-hydroxy-21-ethoxy-23-des(isobutyl)tirucalla-7-ene-23-oic acid gamma-lactone is a natural product found in Aphanamixis grandifolia and Aphanamixis polystachya with data available.
Molecule SMILES: CC12CC(COC(=O)C3C=C(O)C(O)C(O)C3)(OC1(COC(=O)c1ccc(O)c(O)c1O)OC13COc4occ(c41)C3)C(O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Galloyloxypaeoniflorin is a natural product found in Paeonia lactiflora, Medicago truncatula, and other organisms with data available.
Molecule SMILES: CC=C1CN2C3CC1C1(C(=O)OC)C2CC2(c4ccccc4N(C)C32)C1OC(=O)c1cc(OC)c(OC)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: O-trimethoxy-3,4,5-benzoyl-vincamajine is a monoterpenoid indole alkaloid.
Molecule SMILES: COC(=O)CC1CCC(NC(=O)Nc2ccc(C(F)(F)F)cc2)C(CO)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-2-oxanyl]acetic acid methyl ester is a C-glycosyl compound.
Molecule SMILES: C#CC(O)C=CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC=CC#CC(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: petroformyne B is a natural product found in Petrosia ficiformis with data available.
Molecule SMILES: COc1cc(C=O)cc(-c2cc(C=CCOC(C)=O)cc(OC)c2OC(C)=O)c1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-[4-Acetyloxy-3-(2-acetyloxy-5-formyl-3-methoxyphenyl)-5-methoxyphenyl]prop-2-enyl acetate is a natural product found in Pinus taeda with data available.
Molecule SMILES: CCC(=O)N1CC(=O)N2C(CO)C(c3ccc(C#Cc4cccnc4)cc3)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (6R,7R,8R)-8-(hydroxymethyl)-4-(1-oxopropyl)-7-[4-[2-(3-pyridinyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one is a ring assembly, a member of azetidines and a member of benzenes.
Molecule SMILES: COC(=O)c1c2c(c3ccccc3c1OCc1ccccc1)OC(C)(C)C=C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2,2-Dimethyl-6-benzyloxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester is a natural product found in Rubia cordifolia with data available.
Molecule SMILES: CC(C)CC(=O)OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: beta-D-Fructofuranosyl 6-O-(3-methylbutyryl)-alpha-D-glucopyranoside is a natural product found in Coffea arabica with data available.
Molecule SMILES: CC(=O)OC1CC2(C)C(=CCC3C4(C)CCC(OC5OC(C(=O)O)C(O)C(OC6OCC(O)C(O)C6OC6OCC(O)C(O)C6O)C5OC5OC(CO)C(O)C(O)C5O)C(C)(C)C4CCC32C)C2CC(C)(C)C(OC(=O)C=Cc3ccccc3)C(OC(C)=O)C12CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-8,9-diacetyloxy-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-10-[(E)-3-phenylprop-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3-hydroxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid is a natural product found in Camellia sinensis and Camellia sinensis var. sinensis with data available.
Molecule SMILES: CC1=CCC2C(C)(C)C(O)C(O)CC2(C)C1CCc1ccoc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (2S,3S,4aS,8R,8aR)-8-[2-(furan-3-yl)ethyl]-4,4,7,8a-tetramethyl-1,2,3,4a,5,8-hexahydronaphthalene-2,3-diol is a natural product found in Baccharis salicifolia with data available.
Molecule SMILES: COc1ccc(-c2oc3cc(OC4OC(CO)C(O)C(O)C4O)c(OC)c(O)c3c(=O)c2O)cc1CCC(C)COC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(2R)-4-[5-[3,5-dihydroxy-6-methoxy-4-oxo-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-yl]-2-methoxyphenyl]-2-methylbutyl] acetate is a natural product found in Duranta erecta with data available.
Molecule SMILES: COc1cc(C(=O)O)cc(OC2OC(C(=O)O)C(O)C(O)C2O)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 6-(5-carboxy-2-hydroxy-3-methoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid is a tannin.
Molecule SMILES: Cc1ccc2n1C(C)C1OC3(C(C)O)C=Cc4ccc(C)n4C1C23

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1S)-1-[(1R,2S,10R,12R,13R)-4,13,15-trimethyl-11-oxa-3,14-diazapentacyclo[8.8.0.02,12.03,7.014,18]octadeca-4,6,8,15,17-pentaen-10-yl]ethanol is a natural product found in Curvularia with data available.
Molecule SMILES: COc1ccc2c(c1OC)C(=O)c1ccc(C=C(C)CC(=O)O)c(O)c1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Kinanthraquinone B is a monohydroxyanthraquinone that is anthraquinone in which the hydrogen atoms at positions 1, 2, 5 and 6 are replaced hydroxy, 3-methylbut-3-enoic acid, methoxy and methoxy groups, respectively. It is a natural product isolated from Streptomyces sp. SN-593. It has a role as a bacterial metabolite. It is a member of phenols, a monohydroxyanthraquinone, an olefinic compound and a hydroxy monocarboxylic acid.
Molecule SMILES: COc1ccc2c(c1OC)C(=O)c1ccc(C=C(C)CC(=O)O)c(O)c1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (Z)-4-(1-hydroxy-5,6-dimethoxy-9,10-dioxoanthracen-2-yl)-3-methylbut-3-enoic acid is a natural product found in Streptomyces with data available.
Molecule SMILES: CC(=O)OC1CC(C)C2CC3CCC(C)(OC3(C)C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: alpha-Kessyl acetate is a natural product found in Valeriana officinalis with data available.
Molecule SMILES: COc1cc(-c2nc(CO)cs2)c(O)c2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Karamomycin B is a natural product found in Nonomuraea endophytica with data available.
Molecule SMILES: Cc1ccc(O)cn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 5-Hydroxy-2-methylpyridine is a natural product found in Cynoglossum zeylanicum and Panax ginseng with data available.
Molecule SMILES: O=[N+]([O-])c1cc(Cl)c(Cl)c(Cl)c1Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2,3,4,5-tetrachloronitrobenzene appears as pale yellow crystals. (NTP, 1992)
Molecule SMILES: COc1cc(C(O)C(CO)Oc2c(OC)cc(C3OCC4C(c5ccc(O)c(OC)c5)OCC34)cc2OC)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (1R,2S)-2-[4-[(3S,3aR,6S,6aR)-3-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2,6-dimethoxyphenoxy]-1-(4-hydroxy-3-methoxyphenyl)propane-1,3-diol is a natural product found in Helianthus annuus with data available.
Molecule SMILES: O=C(NN=Cc1cn[nH]c1-c1ccc(Cl)cc1)c1ccc([N+](=O)[O-])cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N'-[[3-(4-chlorophenyl)-4-pyrazolylidene]methyl]-4-nitrobenzohydrazide is a C-nitro compound.
Molecule SMILES: COc1cc(O)c2c(ccc3cc(O)cc(O)c32)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 7-Methoxyphenanthrene-2,4,5-triol is a natural product found in Dendrobium nobile with data available.
Molecule SMILES: CCCCCCCCCCC=CCCCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCC)COP(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: PA(13:0/22:1(11Z)) is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC(C)C)c1=NC(=O)c1c(-c2c(F)cccc2Cl)noc1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2-[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]imino-1-(2-methylpropyl)-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxylic acid ethyl ester is a pyridopyrimidine.
Molecule SMILES: Cc1cc(Nc2cc(Cl)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N-[4-[[4-chloro-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]cyclopropanecarboxamide is an aryl sulfide.
Molecule SMILES: C=C1CCC(O)C2(C)CCC3C(C)C(=O)OC3C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 6-hydroxy-3,5a-dimethyl-9-methylidene-3a,4,5,6,7,8,9a,9b-octahydro-3H-benzo[g][1]benzofuran-2-one is a natural product found in Artemisia canariensis and Artemisia thuscula with data available.
Molecule SMILES: O=P(O)(O)OCC(O)C1OC(OP(=O)(O)O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: D-glycero-D-manno-heptose 1,7-bisphosphate is d-glycero-D-manno-heptose in which the hydrogens of the hydroxy groups at positions 1 and 7 are substituted by dihydrogen phosphate groups. It has a role as an Escherichia coli metabolite. It is a conjugate acid of a D-glycero-D-manno-heptose 1,7-bisphosphate(4-).
Molecule SMILES: O=P(O)(O)OCC(O)C1OC(OP(=O)(O)O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: D-Glycero-D-manno-heptose 1,7-bisphosphate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: O=P(O)(O)OCC(O)C1OC(OP(=O)(O)O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: D-Glycero-D-manno-heptose 1,7-bisphosphate is a natural product found in Brassica napus with data available.
Molecule SMILES: CC(=O)OC1CC(C)(C)C(=C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C2C=C3C(C)(C)CC(O)CC3(C)O2)C(C)(O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [3-Hydroxy-4-[16-(6-hydroxy-4,4,7a-trimethyl-2,5,6,7-tetrahydro-1-benzofuran-2-yl)-3,7,12-trimethylheptadeca-1,3,5,7,9,11,13,15-octaenylidene]-3,5,5-trimethylcyclohexyl] acetate is a natural product found in Peridinium bipes with data available.
Molecule SMILES: CC12C(=CCC34COC(=O)C3C=CCC41)C(=O)OC(c1ccoc1)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Salvisplendin B is a natural product found in Salvia splendens with data available.
Molecule SMILES: CC(C)C1CCC2C1(C)CCC1(C)C3CC=C4C(CCC(=O)C4(C)C)C3(C)CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (3R,3aR,5aR,5bS,11aS,11bR,13aS,13bS)-3a,5a,8,8,11b,13a-hexamethyl-3-propan-2-yl-2,3,4,5,5b,6,10,11,11a,12,13,13b-dodecahydro-1H-cyclopenta[a]chrysen-9-one is a natural product found in Bistorta officinalis and Persicaria amphibia with data available.
Molecule SMILES: CCCN(CCC)C1CCc2ccc(O)cc2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol is a member of tetralins.
Molecule SMILES: CC1=CC(c2ccc(O)c(C3Oc4cc(O)ccc4C(=O)C3O)c2)C(C(=O)c2ccc3c(c2O)C=CC(C)(C)O3)C(c2ccc(O)cc2O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Guangsangon F is a natural product found in Morus macroura with data available.
Molecule SMILES: COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Venlafaxine is a serotonin and norepinephrine reuptake inhibitor widely used as an antidepressant. Venlafaxine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury.
Molecule SMILES: COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Venlafaxine is a tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group. It has a role as an antidepressant, a serotonin uptake inhibitor, an adrenergic uptake inhibitor, a dopamine uptake inhibitor, an analgesic, an environmental contaminant and a xenobiotic. It is a member of cyclohexanols, a tertiary alcohol, a tertiary amino compound and a monomethoxybenzene.
Molecule SMILES: COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and panic disorder in adults. The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in 1993 and the extended-release formulation, Effexor XR, was later introduced in 1997.  Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years. It was also considered a second-line treatment for obsessive-compulsive disorder (OCD). Venlafaxine was also investigated in off-label uses for the prophylaxis of migraine headaches, for reduction of vasomotor symptoms associated with menopause, and for the management of neuropathic pain (although there is only minimal evidence of efficacy for this condition).
Molecule SMILES: COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Venlafaxine is a Serotonin and Norepinephrine Reuptake Inhibitor. The mechanism of action of venlafaxine is as a Norepinephrine Uptake Inhibitor, and Serotonin Uptake Inhibitor.
Molecule SMILES: COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Venlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors.  This agent may reduce hormone-related vasomotor symptoms. (NCI04)
Molecule SMILES: O=c1cc(-c2ccc(OC3OC(CO)C(O)C(O)C3O)c(O)c2)oc2cc(O)cc(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Luteolin 4'-glucoside is a natural product found in Physalis lagascae, Physalis minima, and other organisms with data available.
Molecule SMILES: CCCCC#CC#CCCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Tetradecan-7,9-diynoic acid is a long-chain fatty acid.
Molecule SMILES: Clc1cc(-c2c(Cl)ccc(Cl)c2Cl)cc(Cl)c1Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2,3,3',4',5',6-Hexachlorobiphenyl is one of 209 polychlorinated biphenyls (PCBs). PCBs are a group of synthetic organic compounds with 1-10 chlorine atoms attached to biphenyl. They were manufactured as commercial mixtures but banned in the 1970's because they were found to bioaccumulate and cause harmful health effects. However, PCBs do not break down readily and are still found in the environment. (L4)