IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COc1cc(OC)c(C2CC(=O)c3c(O)cc(O)c(CC=C(C)C)c3O2)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Heteroflavanone C is a member of flavanones.
Molecule SMILES: COc1cc(OC)c(C2CC(=O)c3c(O)cc(O)c(CC=C(C)C)c3O2)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Heteroflavanone C is a natural product found in Artocarpus integer with data available.
Molecule SMILES: O=C1CC(c2ccc(O)c(O)c2)c2c(O)cc3c(c2O1)CC(O)C(c1cc(O)c(O)c(O)c1)O3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Sclerophynin A is a natural product found in Castanopsis sclerophylla with data available.
Molecule SMILES: CC(C=CC(=O)OC1C=CC(=O)OC1C(C)CC(C)CC(C)=CC=O)=CC(CO)CCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Trichurusin F is a natural product found in Trichurus terrophilus with data available.
Molecule SMILES: CC1CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(CO)C(O)C6O)C(C)(C)C5CCC43C)C2C1(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2S,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-1-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid is a natural product found in Sanguisorba officinalis with data available.
Molecule SMILES: CC(C)NCC1C(c2ccc(C3=CCCCC3)cc2)C(CO)N1C(=O)CC1CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-[(2S,3R,4S)-3-[4-(1-cyclohexenyl)phenyl]-2-(hydroxymethyl)-4-[(propan-2-ylamino)methyl]-1-azetidinyl]-2-cyclopropylethanone is a ring assembly, a member of azetidines and a member of benzenes.
Molecule SMILES: [C-]#[N+]c1ccc(Sc2ccccc2CN(C)C)c(N)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-[[2-[(dimethylamino)methyl]phenyl]thio]-5-isocyanoaniline is an aryl sulfide.
Molecule SMILES: CC(C)C(=O)C12CCC(C)C1CC(O)C1(C)OC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 1-[(1aR,2R,3aS,4R,6aS,6bS)-2-hydroxy-1a,4-dimethyl-3,3a,4,5,6,6b-hexahydro-2H-indeno[4,5-b]oxiren-6a-yl]-2-methylpropan-1-one is a natural product found in Artemisia annua with data available.
Molecule SMILES: CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Clomiphene is an oral agent used to treat infertility in women desiring pregnancy. Clomiphene has been linked to a low rate of transient serum aminotransferase elevations during therapy and to rare instances of clinically apparent liver injury, which can be severe and even fatal.
Molecule SMILES: CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Clomiphene is a tertiary amine. It has a role as an estrogen antagonist and an estrogen receptor modulator. It derives from a hydride of a stilbene.
Molecule SMILES: CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Enclomiphene is the trans-isomer of clomiphene citrate (CC).  Enclomiphene has a higher rate of clearance and is less active than the cis-isomer, cis-clomiphene.  Clomiphene citrate has been evaluated for antineoplastic activity against breast cancer. (NCI04)
Molecule SMILES: CCN(CC)CCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. [PubChem]
Molecule SMILES: COC12c3c(C)cc(O)c4c(=O)n(C(CC(C)C)C(=O)O)cc(c34)C(=O)C1C13COC(=O)c4c(O)cc(C)c(c41)C(=O)C2C3OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2R)-2-[(1R,2R,13S,14S,24S)-24-acetyloxy-9,19-dihydroxy-13-methoxy-11,17-dimethyl-3,7,15,21-tetraoxo-22-oxa-6-azaheptacyclo[12.9.1.11,16.14,8.02,13.012,26.020,25]hexacosa-4,8,10,12(26),16(25),17,19-heptaen-6-yl]-4-methylpentanoic acid is a natural product found in Talaromyces stipitatus with data available.
Molecule SMILES: CC1CCC(=O)OC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 5,6-Dimethyloxan-2-one is a natural product found in Nicotiana tabacum with data available.
Molecule SMILES: CC1=CCCC2C1(C)C(OC(=O)c1cccnc1)C(OC(=O)c1cccnc1)C1(C)OC3(COC(=O)C3)CC(OC(=O)c3cccnc3)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(1R,3R,4aS,5R,6S,6aS,10aR,10bR)-4a,6a,7,10b-tetramethyl-2'-oxo-5,6-bis(pyridine-3-carbonyloxy)spiro[2,5,6,9,10,10a-hexahydro-1H-benzo[f]chromene-3,4'-oxolane]-1-yl] pyridine-3-carboxylate is a natural product found in Scutellaria barbata with data available.
Molecule SMILES: COc1cccc(Cn2c(-c3nonc3N)nc3ccccc32)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 4-[1-[(3-methoxyphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine is a member of benzimidazoles.
Molecule SMILES: CC(C)=CCCC1(C)C=Cc2c(cc(O)cc2-c2cc3cc(O)c(O)c(CC=C(C)C)c3o2)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-[7-Hydroxy-2-methyl-2-(4-methylpent-3-enyl)chromen-5-yl]-7-(3-methylbut-2-enyl)-1-benzofuran-5,6-diol is a natural product found in Morus macroura with data available.
Molecule SMILES: COc1cc(O)cc2oc(-c3ccc(O)c(O)c3)c(OC3OC(C)C(O)C(O)C3O)c(=O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Azaleatin 3-rhamnoside is a natural product found in Rhododendron simsii and Carya with data available.
Molecule SMILES: Cc1cc(O)c2c(c1)C(=O)c1cc(OS(=O)(=O)O)cc(OC3OC(CO)C(O)C(O)C3O)c1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Sulfemodin 8-O-beta-D-glucoside is a natural product found in Rheum australe with data available.
Molecule SMILES: CCCCCCCCCCCC(O)C1CCC(C(O)CCCCCCCCCCC2CC(CC(C)=O)C(=O)O2)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: cis-Murisolinone is a natural product found in Asimina triloba with data available.
Molecule SMILES: CC(CCO)CCC1C(C)(O)CCC2C(C)(C)CCCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (13R)-Labdane-8,15-diol is a natural product found in Aeonium lindleyi with data available.
Molecule SMILES: [C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[Cr]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Tetracarbonylchromium is an organochromium compound and a metal carbonyl.
Molecule SMILES: CC1=CC2C(O)(CC(CO)=CC3C4C(C)(C)C4(O)CC(C)C32O)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 12-Deoxyphorbol is a natural product found in Euphorbia resinifera with data available.
Molecule SMILES: CC(C)=CC(=O)CC(C)c1ccc(C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2-Methyl-6-(4-methylphenyl)hept-2-en-4-one is a natural product found in Curcuma longa and Curcuma zedoaria with data available.
Molecule SMILES: Cn1c2ccc(O)cc2c(=O)c2ccoc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 6-Hydroxy-9-methylfuro[2,3-b]quinolin-4(9H)-one is a natural product found in Dictamnus albus and Dictamnus dasycarpus with data available.
Molecule SMILES: COc1c(O)cc2c(c1OC)c(=O)c1ccccc1n2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3-Hydroxy-1,2-dimethoxy-10-methylacridin-9-one is a natural product found in Zanthoxylum leprieurii with data available.
Molecule SMILES: CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.[Cl-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor. (NCI04)
Molecule SMILES: COc1cc2c(cc1O)-c1c3c(cc4c1C(C2)NCC4)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (12R)-16-methoxy-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaen-17-ol is a natural product found in Litsea glutinosa with data available.
Molecule SMILES: CC(=O)NCCS(=O)(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Acetyltaurine is an amino sulfonic acid that is taurine substituted by an acetyl group at the N atom. It has a role as a human urinary metabolite and a human blood serum metabolite. It is a member of acetamides and an organosulfonic acid. It is functionally related to a taurine. It is a conjugate acid of an acetyltaurine(1-).
Molecule SMILES: CC(=O)NCCS(=O)(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Acetyltaurine is a natural product found in Vitis vinifera, Synechococcus elongatus, and Drosophila melanogaster with data available.
Molecule SMILES: O=C(NCCC1CCC(NS(=O)(=O)Cc2ccccc2)C(CO)O1)C1CCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: N-[2-[(2R,5S,6R)-5-(benzylsulfonylamino)-6-(hydroxymethyl)oxan-2-yl]ethyl]cyclobutanecarboxamide is a C-glycosyl compound.
Molecule SMILES: C=CCC1=CC2(OC)C(=C(OC)C1=O)OC(c1ccc(OC)c(OC)c1)C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-(3,4-Dimethoxyphenyl)-3a,7-dimethoxy-3-methyl-5-prop-2-enyl-2,3-dihydro-1-benzofuran-6-one is a natural product found in Nectandra amazonum with data available.
Molecule SMILES: CC=C(CO)C(=O)OCC1=CCN2CCC(OC(=O)C=C(C)CO)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Doriasenine is a natural product found in Senecio doria with data available.
Molecule SMILES: CC=C(CO)C(=O)OC1CC(C)C2(C)CC3=C(C)C(=O)OC3(O)CC2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: [(4aR,5S,7R,8aR,9aS)-9a-hydroxy-3,4a,5-trimethyl-2-oxo-5,6,7,8,8a,9-hexahydro-4H-benzo[f][1]benzofuran-7-yl] (Z)-2-(hydroxymethyl)but-2-enoate is a natural product found in Synotis alata with data available.
Molecule SMILES: C=C(C)C1CC=C(C(=O)O)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Perillic acid is an alpha,beta-unsaturated monocarboxylic acid and a cyclohexenecarboxylic acid. It has a role as an antineoplastic agent, a human metabolite and a mouse metabolite. It is a conjugate acid of a perillate.
Molecule SMILES: C=C(C)C1CC=C(C(=O)O)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Perillic acid is a natural product found in Perilla frutescens and Homo sapiens with data available.
Molecule SMILES: CC(=Cc1cc(C)co1)CCCC1=CC(=O)OC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: E-7,12,13H-5-Dehydro-12-oxolasiosperman is a natural product found in Athanasia with data available.
Molecule SMILES: CCC(C)C(OC(C)=O)C(C)C1=C(O)C(=O)C2=C(OC3(C)CCC4OC(C(C)(C)O)CC(O)C4(C)C3C2O)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Arthripenoid D is a natural product found in Arthrinium with data available.
Molecule SMILES: COCC(=O)Nc1ccc2c(c1)OCC(C)N(C(=O)Cc1ccccn1)CC(C)C(OC)CN(C)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2-methoxy-N-[(5S,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-[1-oxo-2-(2-pyridinyl)ethyl]-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]acetamide is an azamacrocycle and a lactam.
Molecule SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1-tetradecanoyl-2-hexadecanoyl-3-[(9Z)-octadecenoyl]-sn-glycerol is a triacyl-sn-glycerol in which the which the acyl groups at positions 1, 2 and 3 are specified as tetradecanoyl, hexadecanoyl and (9Z)-octadecenoyl respectively. It has a role as a human blood serum metabolite. It is a triacyl-sn-glycerol and a TG(14:0/16:0/18:1).
Molecule SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: TG(14:0/16:0/18:1(9Z)) is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: O=C(O)CCc1nc2ccccc2n1CCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 3-[1-(2-carboxyethyl)-1H-benzo[d]imidazol-2-yl]propanoic acid is a member of benzimidazoles.
Molecule SMILES: O=C(C=Cc1ccc(O)c(O)c1)c1ccc(O)c(OC2OC(CO)C(O)C(O)C2O)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (E)-3-(3,4-dihydroxyphenyl)-1-[2,4-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one is a natural product found in Bidens pilosa with data available.
Molecule SMILES: CC1OC(=O)C=C2C3=C(OC(C)(C)CC3)C(=O)C(O)=C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Fuscin is a natural product found in Oidiodendron griseum with data available.
Molecule SMILES: CCCCCCCCCCCC=CC(O)C(N)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Hexadecasphing-4-enine is a sphingoid that is the C16 analogue of sphingosine. It has a role as a mouse metabolite. It is a sphingoid and an aminodiol. It is a conjugate base of a hexadecasphing-4-enine(1+).
Molecule SMILES: CCCCCCCCCCCC=CC(O)C(N)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Hexadecasphingosine is a natural product found in Klebsiella pneumoniae with data available.
Molecule SMILES: CC(C)CCCC(C)C1CCC2(O)C3=CC(=O)C4CC(O)CCC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2,22,25-trideoxyecdysone is a 3beta-hydroxy steroid that is 5beta-cholestane containing a double bond between positions 7 and 8, and substituted by an oxo group at position 6 and by hydroxy groups at the 3beta and 14alpha positions. It is a 3beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 6-oxo steroid and an enone. It is functionally related to an ecdysone. It derives from a hydride of a 5beta-cholestane.
Molecule SMILES: COc1cc2c(c(O)c1O)CC1C(C2=O)c2ccccc2C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (4bR,10aS)-8,9-dihydroxy-7-methoxy-11,11-dimethyl-10,10a-dihydro-4bH-benzo[b]fluoren-5-one is a natural product found in Carex distachya with data available.
Molecule SMILES: NC(C(=O)O)C(O)c1ccc(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Droxidopa is an orally available prodrug of norepinephrine that is used in the treatment of symptomatic orthostatic hypotension due to neurogenic causes of autonomic failure. Droxidopa has had limited clinical use, but has not been linked to serum enzyme elevations nor to instances of clinically apparent acute liver injury.
Molecule SMILES: NC(C(=O)O)C(O)c1ccc(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Droxidopa is a serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension It has a role as a prodrug, a vasoconstrictor agent and an antihypertensive agent. It is a L-tyrosine derivative and a member of catechols.
Molecule SMILES: NC(C(=O)O)C(O)c1ccc(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a deficit of noradrenaline as well as of dopamine in Parkinson's disease and it has been proposed that this underlies the sudden transient freezing seen usually in advanced disease.  Though L-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in clinical trials at the phase III point in the United States (U.S.), Canada, Australia, and throughout Europe. Provided L-DOPS successfully completes clinical trials, it could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. Additionally, phase II clinical trials for intradialytic hypotension are also underway. Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is the pharmaceutical company developing it in that country.
Molecule SMILES: NC(C(=O)O)C(O)c1ccc(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: The physiologic effect of droxidopa is by means of Increased Blood Pressure.
Molecule SMILES: CCC(C)C1NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)CNC(=O)C2CCCCN2C(=O)C(NC(=O)C(CC(=O)O)NC(=O)C=CCCCCCCCCCC(C)C)CNC(=O)C2CCCN2C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (3S)-4-[[(3S,7S,13S,16R,22S,28S)-13-butan-2-yl-22,28-bis(carboxymethyl)-16-(1-hydroxyethyl)-2,6,12,15,18,21,24,27,30,33-decaoxo-1,5,11,14,17,20,23,26,29,32-decazatricyclo[32.4.0.07,11]octatriacontan-3-yl]amino]-3-[[(E)-13-methyltetradec-2-enoyl]amino]-4-oxobutanoic acid is a natural product found in Actinomyces and Streptomyces viridochromogenes with data available.