IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(C)(O)c1ccc2c(c1)C(=O)CC1C(C)(O)CCCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 1-hydroxy-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one is a natural product found in Larix kaempferi with data available.
Molecule SMILES: CCCCCC=CC=CC=CC(=O)CC(O)CC(O)CC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Virensol D is a polyketide.
Molecule SMILES: COc1ccc2c(c1)OC(c1ccc(O)cc1)CC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Liquiritigenin 7-methylether is a natural product found in Oxytropis falcata, Muntingia calabura, and other organisms with data available.
Molecule SMILES: COc1ccc(CCn2c(-c3ccncc3)n[nH]c2=S)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 4-[2-(3,4-dimethoxyphenyl)ethyl]-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione is a member of triazoles.
Molecule SMILES: COc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N(C(C)CO)CC(C)C(CN(C)C(=O)Cc2ccccc2)OCCCCC(C)O3)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-[[(3S,9R,10S)-12-[(2R)-1-hydroxypropan-2-yl]-16-[(4-methoxyphenyl)sulfonylamino]-3,10-dimethyl-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-9-yl]methyl]-N-methyl-2-phenylacetamide is a lactam and an azamacrocycle.
Molecule SMILES: CCCCCCCC=CC(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Methyl 2-decenoate is a fatty acid ester.
Molecule SMILES: CC(O)c1nc2ccccc2c(=O)[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Chrysogine is a quinazolin-4-one where the hydrogen atom in position 2 is substituted with a 1-hydroxyethyl group. It is a natural yellow pigment found in many filamentous fungi, including the Aspergillus, Penicillium and Fusarium genera. It has a role as a biological pigment, an Aspergillus metabolite and a marine metabolite. It is a quinazoline alkaloid, a secondary alcohol, a member of quinazolines, a cyclic amide and a secondary amide.
Molecule SMILES: CC(O)c1nc2ccccc2c(=O)[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-(1-Hydroxyethyl)-4(3H)-quinazolinone is a natural product found in Fusarium lateritium with data available.
Molecule SMILES: O=C(OC1C(O)C(O)OC(CO)C1O)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3-O-galloyl-beta-d-glucose is a natural product found in Terminalia citrina and Syzygium cumini with data available.
Molecule SMILES: CC(C)C(C)CCC(C)C1CCC2C3=CC(O)C4(O)CC(O)CCC4(C)C3(O)CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 5alpha-Ergost-7-ene-3beta,5,6beta,9-tetrol is a natural product found in Amanita pantherina with data available.
Molecule SMILES: CC12CCC(=O)C1=CC(=O)OC2c1ccoc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Trichiconnarin A is a natural product found in Heynea trijuga with data available.
Molecule SMILES: CC(N)C(N)CCCCCC(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 7,8-diaminononanoate is an amino-acid anion. It has a role as a Saccharomyces cerevisiae metabolite. It is functionally related to a nonanoate. It is a conjugate base of a 7,8-diaminononanoic acid.
Molecule SMILES: CC(N)C(N)CCCCCC(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 7,8-Diaminononanoate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: NC(CCC(=O)NC(=O)C(N)CO)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Serinyl-Gamma-glutamate is a glutamine derivative.
Molecule SMILES: CC1=CC2C(CCC3(C)OC3C3C(O)C(CO)CC3(OC(=O)C=Cc3ccccc3)C1=O)C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: latilagascene B is a natural product found in Euphorbia lagascae with data available.
Molecule SMILES: CC(C)c1cc2c(cc1O)C=CC1C(C)(C)CCCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 4b,8,8-Trimethyl-3-propan-2-yl-5,6,7,8a-tetrahydrophenanthren-2-ol is a natural product found in Salvia apiana with data available.
Molecule SMILES: Oc1cc(O)cc(Oc2c(O)cc(Oc3c(O)cc(Oc4c(O)cc(O)cc4O)cc3O)cc2O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Tetraphlorethol C is a natural product found in Ecklonia maxima, Ascophyllum nodosum, and other organisms with data available.
Molecule SMILES: C=C(C)C1=CC2(C)C(=CC1=O)CCC(O)C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (4aR,5R,6R)-6-hydroxy-3-isopropenyl-4a,5-dimethyl-5,6,7,8-tetrahydronaphthalen-2-one is a natural product found in Penicillium copticola and Penicillium with data available.
Molecule SMILES: O=C(O)C1OC(Oc2cc(O)c3c(=O)cc(-c4ccc(O)cc4)oc3c2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Apigenin-7-o-glucuronide is a natural product found in Scutellaria albida, Penstemon serrulatus, and other organisms with data available.
Molecule SMILES: COc1ccc(C(=O)C(C)O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-Hydroxy-1-(4-methoxyphenyl)propan-1-one is a natural product found in Pleurotus pulmonarius with data available.
Molecule SMILES: COc1cccc2c1C(=O)C(C(C)O)=C(CC(C)=O)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 3-[(1R)-1-hydroxyethyl]-5-methoxy-2-(2-oxopropyl)naphthalene-1,4-dione is a natural product found in Eleutherine bulbosa with data available.
Molecule SMILES: COc1c2c(c(O)c3c1C(O)Cc1cc(CC(C)O)c(C(=O)O)c(O)c1-3)C(=O)c1cccc(O)c1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (6S)-1,6,9,14-tetrahydroxy-3-[(2S)-2-hydroxypropyl]-7-methoxy-8,13-dioxo-5,6-dihydrobenzo[a]tetracene-2-carboxylic acid is a natural product found in Streptosporangium roseum with data available.
Molecule SMILES: Br.COc1cc2[nH]c3c(C)nccc3c2cc1Br

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 6-bromoharmine hydrobromide is a hydrobromide salt prepared from 6-bromoharmine and 1 equivalent of hydrogen bromide. It is semisynthetic derivative of harmine and has been shown to exhibit significant anti-HIV activity. It contains a 6-bromoharminium(1+).
Molecule SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(C)CCC1C23C=CC2(CC(OC4OC(CO)C(O)C(O)C4O)CCC12C)OO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ergosterol peroxide glucoside is a natural product found in Sarcodon scabrosus, Hydnellum scabrosum, and Hypholoma fasciculare with data available.
Molecule SMILES: CC(O)C(NC(=O)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O)C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]threonate is a hydroxy monocarboxylic acid anion that is the conjugate base of N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]threonine, obtained by deprotonation of the carboxy group; major species at pH 7.3. It has a role as an Escherichia coli metabolite and a human metabolite. It is a conjugate base of a N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]threonine.
Molecule SMILES: CC1OC(OC2CC(c3ccc4c(c3O)C(=O)c3ccc5c(c3C4=O)C(=O)CC(C)(O)C5)OC(C)C2O)CCC1OC1CC(O)C(O)C(C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (3R)-9-[(4R,5R,6R)-4-[(2S,5S,6S)-5-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]-3,8-dihydroxy-3-methyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trione is a natural product found in Streptomyces fradiae with data available.
Molecule SMILES: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c1ccc(Cl)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Esfenvalerate is a synthetic pyrethroid insecticide which is used on a wide range of pests such as moths, flies, beetles, and other insects. It is used on vegetable crops, tree fruit, and nut crops. It may be mixed with a wide variety of other types of pesticides such as carbamate compounds or organophosphates. Esfenvalerate has replaced the naturally occurring compound fenvalerate (to which it is almost identical) for use in the U.S. Much of the data for fenvalerate is applicable to the pesticide esfenvalerate because the two compounds contain the same components. The only differences in the two products are the relative proportions of the four separate constituents (isomers). Esfenvalerate has become the preferred compound because it requires lower applications rates than fenvalerate, is less chronically toxic, and is a more powerful insecticide. The compound contains a much higher percentage of the one insecticidally active isomer (84% for esfenvalerate and 22% for fenvalerate). A pyrethroid is a synthetic chemical compound similar to the natural chemical pyrethrins produced by the flowers of pyrethrums (Chrysanthemum cinerariaefolium and C. coccineum). Pyrethroids are common in commercial products such as household insecticides and insect repellents. In the concentrations used in such products, they are generally harmless to human beings but can harm sensitive individuals. They are usually broken apart by sunlight and the atmosphere in one or two days, and do not significantly affect groundwater quality except for being toxic to fish. (L811, L871, L876)
Molecule SMILES: CCCC(=O)NC(CC(=O)O)C(=O)NC1C(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCC(O)C(C2=O)N(Cc2ccccc2)C(=O)N(C)C(Cc2ccc(O)cc2)C(=O)NC(C(C)C)C(=O)OC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 4-[[2-Benzyl-21-hydroxy-5,15-bis[(4-hydroxyphenyl)methyl]-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-2,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(butanoylamino)-4-oxobutanoic acid is a natural product found in Nostoc edaphicum with data available.
Molecule SMILES: COC1=C(OC)C23CCc4ccc(OC)c(OC)c4C2(CC1=O)CC(=O)N3C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (1R,10S)-3,4,11,12-tetramethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraene-13,16-dione is a natural product found in Stephania japonica with data available.
Molecule SMILES: CC=C(C)C(=O)OC1C(O)C(CO)OC(OC2C(C)OC3OC4C(OC(CO)C(O)C4O)OC4C(OC(CCCCC)CCCCCCCCCC(=O)OC2C3OC(=O)C(C)CC)OC(C)C(O)C4O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(1R,3R,4S,5R,6R,8S,10S,11R,12R,13R,15S,17S,29S,30S,31R,33S)-30-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(E)-2-methylbut-2-enoyl]oxyoxan-2-yl]oxy-4,5,11,12-tetrahydroxy-6-(hydroxymethyl)-13,31-dimethyl-27-oxo-17-pentyl-2,7,9,14,16,28,32-heptaoxatetracyclo[27.3.1.03,8.010,15]tritriacontan-33-yl] (2R)-2-methylbutanoate is a natural product found in Ipomoea orizabensis with data available.
Molecule SMILES: O=C([O-])CCC1=C(CC(=O)[O-])c2cc3nc(cc4[nH]c(cc5[nH]c(cc1n2)c(CC(=O)[O-])c5CCC(=O)[O-])c(CCC(=O)[O-])c4CC(=O)[O-])C(CC(=O)[O-])=C3CCC(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Uroporphyrin III(8-) is a cyclic tetrapyrrole anion obtained by deprotonation of the carboxy groups of uroporphyrin III; major species at pH 7.3. It is a conjugate base of a uroporphyrin III.
Molecule SMILES: CCC(C)C(NC(=O)C(CC(=O)NO)Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: JMV 390-1 is a dipeptide. It has a role as a non-narcotic analgesic and a protease inhibitor.
Molecule SMILES: CCCCC1(C(O)CC=C(C)C)C(=O)c2c(O)ccc(O)c2C(=O)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: alpha-Methyl-n-butylshikonin is a natural product found in Lithospermum erythrorhizon and Arnebia euchroma with data available.
Molecule SMILES: C=C1C(C(C)C2CC=C(C)C(=O)O2)=CCC2(C)C1CC1(O)C2CC(O)C2C(C)(C)OC(=O)C=CC23OC13

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (1R,2R,4R,10S,11R,13S,14R,19R)-1,11-dihydroxy-9,9,14-trimethyl-18-methylidene-17-[(1R)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-3,8-dioxapentacyclo[11.7.0.02,4.04,10.014,19]icosa-5,16-dien-7-one is a natural product found in Kadsura longipedunculata with data available.
Molecule SMILES: CCCCc1cc(CC2CNCCC2CC(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)no1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 1-[1-({(3r,4s)-3-[(5-butyl-1,2-oxazol-3-yl)methyl]-4-piperidinyl}acetyl)-4-piperidinyl]-1,3-dihydro-2h-benzimidazol-2-one is an organonitrogen compound and an organooxygen compound. It is functionally related to a delta-amino acid.
Molecule SMILES: CC=C(C)C(=O)OC1C(OC(C)=O)C2(CO)C(CC1(C)C)C1=CCC3C4(C)CCC(OC5OC(C(=O)O)C(O)C(OC6OC(CO)C(O)C6O)C5OC5OC(CO)C(O)C(O)C5O)C(C)(C)C4CCC3(C)C1(C)C(O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Aesculioside IIf is a natural product found in Aesculus pavia with data available.
Molecule SMILES: O=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(OC3OC(CO)C(O)C(O)C3O)c(O)cc(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Gossypin is a glycosyloxyflavone that is gossypetin attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage. It has a role as a neuroprotective agent and a plant metabolite. It is a 7-hydroxyflavonol, a pentahydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a gossypetin.
Molecule SMILES: O=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(OC3OC(CO)C(O)C(O)C3O)c(O)cc(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Gossypin is a natural product found in Drosera rotundifolia, Rhodiola rosea, and other organisms with data available.
Molecule SMILES: CC(C)=CCC12CC3C(C4OC4(C)C)C(CC=C(C)C)(C1=O)C(=O)C(C(=O)c1ccccc1)(C2=O)C3(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1S,3R,5S,7S,8S)-5-benzoyl-8-[(2R)-3,3-dimethyloxiran-2-yl]-6,6-dimethyl-1,3-bis(3-methylbut-2-enyl)adamantane-2,4,9-trione is a natural product found in Hypericum sampsonii with data available.
Molecule SMILES: O=S(=O)(O)OC1C(O)OC(CO)C(O)C1OS(=O)(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [2,5-Dihydroxy-6-(hydroxymethyl)-3-sulfooxyoxan-4-yl] hydrogen sulfate is a natural product found in Didemnum molle with data available.
Molecule SMILES: CC(O)(CCCCCCCCC=CC=Cc1ccccc1)CC1(C)OC(=O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Seco-plakortolide O is a butan-4-olide that is dihydrofuran-2(3H)-one substituted by a hydroxy group at position 4, a 2-hydroxy-2-methyl-14-phenyltetradeca-11,13-dien-1-yl group at position 5 and a methyl group at position 5 (the 4R,5R stereoisomer). It is isolated from the Australian marine sponge Plakinastrella clathrata. It has a role as a metabolite. It is a butan-4-olide and a diol.
Molecule SMILES: CCC(C)C(NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(N)CO)C(C)CC)C(C)O)C(C)C)C(C)O)C(=O)NC(C)C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Corticorelin, available commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human corticotropin-releasing hormone (hCRH), a potent stimulator of adrenocorticotropic hormone (ACTH) release from the anterior pituitary. Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the pituitary to release ACTH.   It is used as a diagnostic agent to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion. It provides a differential diagnosis for Cushing's disease (a pituitary source of ACTH excess) or of ectopic ACTH syndrome (an ectopic source of ACTH excess). If corticorelin injection results in an increase of plasma ACTH and cortisol, the patient is diagnosed with Cushing's disease. However, if corticorelin injection does not result in an increase of plasma ACTH and cortisol, the patient is diagnosed with ectopic ACTH syndrome.
Molecule SMILES: CCC(C)C(NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(N)CO)C(C)CC)C(C)O)C(C)C)C(C)O)C(=O)NC(C)C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Corticorelin Ovine is a recombinant ovine corticotropin-releasing hormone (CRH), a 41 amino acids peptide similar to human CRH, used as a diagnostic agent. Corticorelin ovine is a potent stimulator of adrenocorticotropic hormone (ACTH), secreted from the anterior pituitary gland. In turn, ACTH stimulates cortisol production from the adrenal cortex and is regulated by a negative feedback mechanism. Corticorelin ovine triflutate is used as a diagnostic tool in differentiating pituitary and ectopic production of ACTH.
Molecule SMILES: CC(=O)Nc1ccc(OC(C)(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Butacetin is an anilide and a member of acetamides.
Molecule SMILES: COc1c(O)ccc2c1OC(c1ccc(O)c(O)c1)CC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2S)-2-(3,4-dihydroxyphenyl)-7-hydroxy-8-methoxy-2,3-dihydrochromen-4-one is a natural product found in Coreopsis grandiflora with data available.
Molecule SMILES: O=C(Nc1nccs1)c1ccc(COc2ccccc2Cl)o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 5-[(2-chlorophenoxy)methyl]-N-(2-thiazolyl)-2-furancarboxamide is an aromatic ether.