IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(=O)OC1CC=C(C)C2C(O)C3(O)C(C=C(CCl)CCC(OC(C)=O)C12C)OC(=O)C3C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: [(1S,2R,3R,4R,7S,8E,12S,13S,14S)-14-acetyloxy-9-(chloromethyl)-2,3-dihydroxy-4,13,17-trimethyl-5-oxo-6-oxatricyclo[11.4.0.03,7]heptadeca-8,16-dien-12-yl] acetate is a natural product found in Briareum stechei with data available.
Molecule SMILES: CC1CC(=O)c2c(ccc3c2C(=O)c2cccc(OC4OC(C)C(O)C(O)C4O)c2C3=O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (3S)-3-methyl-8-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3,4-dihydro-2H-benzo[a]anthracene-1,7,12-trione is a natural product found in Streptomyces atratus with data available.
Molecule SMILES: CCC1C2c3ccc(C(=O)CC(C)C(=O)O)n3CCCC2OC12C=C(C)C(=O)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 4-(3-Ethyl-4'-methyl-5'-oxospiro[5-oxa-10-azatricyclo[8.3.0.02,6]trideca-1(13),11-diene-4,2'-furan]-11-yl)-2-methyl-4-oxobutanoic acid is a natural product found in Stemona tuberosa with data available.
Molecule SMILES: CSC1(Cc2ccccc2)NC(=O)C2(SC)CC3=COC=CC(O)C3N2C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Emestrin H is a natural product found in Podospora australis with data available.
Molecule SMILES: CC(C)CC1OC(=O)CCNC(=O)C(C(C)C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(Cc2ccccc2)NC(=O)C2C(C)CCN2C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: isaridin C2 is a natural product found in Beauveria felina and Isaria with data available.
Molecule SMILES: C=C(C)C(=O)OC1C2C(=C)C(=O)OC2CC(C)C2C=CC(=O)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (5,8a-Dimethyl-1-methylidene-2,8-dioxo-3a,4,5,5a,9,9a-hexahydroazuleno[6,5-b]furan-9-yl) 2-methylprop-2-enoate is a natural product found in Arnica montana with data available.
Molecule SMILES: CCC(C)C(NC(Cc1cn(C)c2ccccc12)C(=O)NC=Cc1ccc(OC2OC(C)C(NC(C)=O)C(O)C2O)cc1)C(=O)NCCc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Rhabdoplanin D is a natural product found in Xenorhabdus bovienii with data available.
Molecule SMILES: CC(C)CCCC(C)C1CCCC2C1(C)CCC1C23C=CC2(CC(O)CCC12C)OO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1S,2R,6R,7R,10R,11R,14S,16S)-7,11-dimethyl-6-[(2R)-6-methylheptan-2-yl]-17,18-dioxapentacyclo[14.2.2.01,10.02,7.011,16]icos-19-en-14-ol is a natural product found in Pseudoceratina purpurea with data available.
Molecule SMILES: CC(O)C(CO)NC(=O)C1CSSCC(NC(=O)C(N)Cc2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)N1.Cl.Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: CAM2029 is a new ready-to-use, long-acting octreotide formulation being developed for the long-term treatment of acromegaly, carcinoid syndrome and vasoactive intestinal peptide (VIP)-producing tumours. CAM2029 was found to provide long-acting release of octreotide resulting in a statistically significant suppression of a clinical biomarker insulin-like growth factor 1 (IGF-1) over the target one-month therapeutic period.
Molecule SMILES: CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(NS(=O)(=O)c2ccc(F)cc2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide is a member of pyrrolidines.
Molecule SMILES: Oc1ccc(C=Cc2cc(O)cc3c2C(c2cc(O)cc4c2C(c2cc(O)cc5c2C(c2cc(O)cc(O)c2)C(c2ccc(O)cc2)O5)C(c2ccc(O)cc2)O4)C(c2ccc(O)cc2)O3)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5-[(2S,3S)-6-hydroxy-4-[(2R,3R)-6-hydroxy-4-[(2S,3S)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(Z)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol is a natural product found in Carex pendula with data available.
Molecule SMILES: COC(=O)C12CCC(C)CC1C1=CCC3C4(C)CCC(O)C(C)(C)C4CCC3(C)C1(C)CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: methyl (2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,6a,6b,9,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate is a natural product found in Cunila lythrifolia with data available.
Molecule SMILES: [C-]#[N+]C(C)(C)C1CCC(C)(C2CCC(=C)C3CCC(C)(O)C(N=C=S)C32)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Kalihinol L is a natural product found in Acanthella pulcherrima with data available.
Molecule SMILES: COC(=O)C12OCC34C(CC5C(C)C(O)C(O)CC5(C)C3C(O)C1O)OC(=O)C(OC(=O)C=C(C)C)C24

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Javanicolide C is a natural product found in Brucea javanica with data available.
Molecule SMILES: CC1CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(=O)C(C)(C)C5CCC43C)C2C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1S,2R,4aS,6aS,6aS,6bR,8aR,12aR,14bR)-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,5,6,6a,7,8,8a,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid is a natural product found in Geum japonicum, Geum macrophyllum, and other organisms with data available.
Molecule SMILES: COc1ccccc1S(=O)(=O)N(C)CC1OCc2cnnn2CCCC(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-2-methoxy-N-methylbenzenesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CC(C=CC=C(C)C=CC=C(C)C=CC(OC1OC(C)C(O)C(O)C1O)C(C)(C)O)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)CC(O)CC1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (2S,3S,4R,5R,6S)-2-[(3S,4E,6E,8E,10E,12E,14E,16E,18E,20E,22E,24E)-2-hydroxy-25-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-2,6,10,14,19,23-hexamethylpentacosa-4,6,8,10,12,14,16,18,20,22,24-undecaen-3-yl]oxy-6-methyloxane-3,4,5-triol is a natural product found in Planktothrix agardhii with data available.
Molecule SMILES: CN(C)C(=O)c1cccc(-c2ccc(C3C(CO)N4CCCCN(CC5CCOCC5)CC34)cc2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 3-[4-[(8S,9R,10S)-10-(hydroxymethyl)-6-(4-oxanylmethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]-N,N-dimethylbenzamide is a member of biphenyls.
Molecule SMILES: C=C1C=C(c2ccc(O)c(OC)c2)Cc2cc(OCC(O)C(O)C(O)C=O)cc(O)c21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2S,3R,4R)-2,3,4-trihydroxy-5-[[4-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-5-methylidene-8H-naphthalen-2-yl]oxy]pentanal is a natural product found in Schouwia purpurea and Schouwia thebaica with data available.
Molecule SMILES: COC(=O)CC1C2(C)C3=C(C)C(c4ccoc4)CC3OC2C(OC(C)=O)C2C(C)(CO)C=CC(=O)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: methyl 2-[(1S,2R,3R,4R,8R,9S,10R,13R,15R)-2-acetyloxy-13-(furan-3-yl)-4-(hydroxymethyl)-4,8,10,12-tetramethyl-7-oxo-16-oxatetracyclo[8.6.0.03,8.011,15]hexadeca-5,11-dien-9-yl]acetate is a natural product found in Azadirachta indica with data available.
Molecule SMILES: COc1c(C)c(OC2OC(CO)C(O)C(O)C2O)c(C=O)c2c1C(=O)C(Cc1ccc3c(c1)OCO3)CO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Ophiopogoside B is a natural product found in Ophiopogon japonicus with data available.
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)OCC1OC(Oc2cc(O)cc(C=Cc3ccc(O)cc3)c2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3-[[6-O-[(E)-3-(4-Hydroxyphenyl)propenoyl]-beta-D-glucopyranosyl]oxy]-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenol is a natural product found in Eucalyptus rubida with data available.
Molecule SMILES: O=C(O)CC(=O)OC1OC(C(=O)O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 6-[(2-carboxyacetyl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid is a glucosiduronic acid.
Molecule SMILES: O=c1c2cccc(O)c2nc2n1CCC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 5-hydroxy-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one is a natural product found in Klebsiella pneumoniae with data available.
Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCCCC(O)C(=O)NC(COP(=O)(O)OC1C(O)C(O)C(O)C(O)C1O)C(O)C(O)CCCCCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-[3,4-Dihydroxy-1-({hydroxy[(2,3,4,5,6-pentahydroxycyclohexyl)oxy]phosphoryl}oxy)octadecan-2-yl]-2-hydroxyhexacosanimidic acid is a phosphosphingolipid.
Molecule SMILES: CC1CCC(C(C)C2C(O)CC3C4CC=C5CC(OC6OC(CO)C(O)C(O)C6O)CCC5(C)C4CCC32C)=NC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3-Glucopyranosyletioline is a natural product found in Solanum spirale with data available.
Molecule SMILES: C=C1C(=O)OC2C1C(OC(=O)C1(C)OC1C)C(OC(C)=O)C(C(=O)OC)=CCCC1(C)OC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: CID 5281441 is a natural product found in Smallanthus sonchifolius, Enydra fluctuans, and Melampodium longipilum with data available.
Molecule SMILES: CC(=CC(C)O)C(O)C(C)C=CC=CCCC(O)CC1=C(C)C(=O)C(C)(O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-hydroxy-2,4-dimethyl-5-[(2R,5E,7E,9R,10R,11E,13R)-2,10,13-trihydroxy-9,11-dimethyltetradeca-5,7,11-trienyl]furan-3-one is a natural product found in Sphaerimonospora mesophila with data available.
Molecule SMILES: COC(=O)C(C)C1OC(=O)C=C2C1CC1OC(=O)C3(C)C4OC4CC2(C)C13

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Salignone J is a natural product found in Podocarpus salignus with data available.
Molecule SMILES: C=C1C(=O)C=C2C(C)CCC3C(C12)C3(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (1aS)-1a,2,3,4,6,7,7abeta,7balpha-Octahydro-1,1,4alpha-trimethyl-7-methylene-1H-cycloprop[e]azulen-6-one is a natural product found in Calypogeia azurea with data available.
Molecule SMILES: COC1CN(C)C(=O)c2ccc(NS(=O)(=O)CC(F)(F)F)cc2OCC(C)NCC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2,2,2-trifluoro-N-[(5S,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]ethanesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CC1CC2CC(=O)C3(O)CCC[N+]4([O-])CCCC2(O)C34C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (1R,2S,6R,10R,13S,15S)-2,10-dihydroxy-15-methyl-6-oxido-6-azoniatetracyclo[8.6.0.01,6.02,13]hexadecan-11-one is a natural product found in Huperzia serrata with data available.
Molecule SMILES: CC=Cc1ccc2oc(-c3ccc(OC)cc3O)cc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 5-Methoxy-2-(5-prop-1-enyl-1-benzofuran-2-yl)phenol is a natural product found in Krameria bicolor, Krameria lappacea, and other organisms with data available.
Molecule SMILES: CC1CCCCOC(CN(C)Cc2ccncc2)C(C)CN(C(C)CO)C(=O)c2cc(NS(C)(=O)=O)ccc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-[(3R,9S,10S)-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-9-[[methyl(pyridin-4-ylmethyl)amino]methyl]-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]methanesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CCCCCC=CCC=CCC=CCCCCC(=O)OC(COCCCCCCCCCCCCCCCCCC)COP(=O)(O)OCC(O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: PG(O-18:0/18:3(6Z,9Z,12Z)) is a member of glycerophosphoglycerols.
Molecule SMILES: CCC(C)C1NC(=O)c2csc(n2)C(C)NC(=O)C2N=C(OC2C)C(CC(C)C)NC(=O)c2csc(n2)C(Cc2ccccc2)NC(=O)C2N=C1OC2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Patellamide B is a cyclic peptide.
Molecule SMILES: CCC(C)C1NC(=O)c2csc(n2)C(C)NC(=O)C2N=C(OC2C)C(CC(C)C)NC(=O)c2csc(n2)C(Cc2ccccc2)NC(=O)C2N=C1OC2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Patellamide B is a natural product found in Prochloron and Lissoclinum patella with data available.
Molecule SMILES: CCN(CC)c1ccc2cc(-c3nc4cc(S(N)(=O)=O)ccc4o3)c(=O)oc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3-[5-(Aminosulfonyl)benzoxazol-2-yl]-7-(diethylamino)coumarin is a member of coumarins.
Molecule SMILES: COC1CC(OC2C(C)OC(OC3C(C)OC(OC4CCC5(C)C(=CCC6(O)C5CC(OC(=O)c5cccnc5)C5(C)C(O)(C(C)=O)CCC65O)C4)CC3OC)CC2OC)OC(C)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(3S,8S,9R,10R,12R,13S,14R,17S)-17-acetyl-8,14,17-trihydroxy-3-[(2R,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] pyridine-3-carboxylate is a natural product found in Cynanchum boudieri and Cynanchum caudatum with data available.
Molecule SMILES: CC1(Cl)CC2OC3(Br)C=CC(C)(O)C2(CC1Br)C3(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (3S,4S,8R,11R)-3,8-dibromo-4-chloro-4,11,12,12-tetramethyl-7-oxatricyclo[6.3.1.01,6]dodec-9-en-11-ol is a natural product found in Laurencia translucida with data available.
Molecule SMILES: Cc1cc(O)c2c(c1)C(O)(C1OC(OC(=O)c3ccccc3)C(O)C(O)C1O)c1cc(O)cc(O)c1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Mayoside is a natural product found in Picramnia antidesma, Picramnia teapensis, and Picramnia hirsuta with data available.
Molecule SMILES: CC(C)C(=O)c1c(O)c2c(c3c1OC1(O)C(C3C(C)C)C(O)C(C)(C)C(=O)C1(C)C)OC1=C(C(=O)C(C)(C)C(=O)C1(C)C)C2C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (4aS,8R,14S,14aR)-1,4a,7-trihydroxy-2,2,4,4,10,10,12,12-octamethyl-6-(2-methylpropanoyl)-8,14-di(propan-2-yl)-1,8,14,14a-tetrahydrochromeno[2,3-a]xanthene-3,9,11-trione is a natural product found in Corymbia scabrida with data available.
Molecule SMILES: CC(C)(C)c1ccc(Oc2ccc(N)cn2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: CB-103 is under investigation in clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies).
Molecule SMILES: CC(C)(C)c1ccc(Oc2ccc(N)cn2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: pan-NOTCH Protein-Protein Interaction Inhibitor CB-103 is an orally bioavailable protein-protein interaction (PPI) inhibitor that targets the assembly of the NOTCH transcription complex, with potential antineoplastic activity. Upon oral administration, pan-NOTCH PPI inhibitor CB-103 targets and inhibits the NOTCH transcriptional activation complex in the cell nucleus. This inhibits the expression of NOTCH target genes and prevents NOTCH signaling, which may inhibit the proliferation of tumor cells mediated by an overly-active Notch pathway. Overactivation of the Notch signaling pathway, often triggered by activating mutations, has been correlated with increased cellular proliferation and poor prognosis in certain tumor types.
Molecule SMILES: CCCN(C)CC1OCc2cn(nn2)CCCC(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-9-[[methyl(propyl)amino]methyl]-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one is an azamacrocycle and a lactam.
Molecule SMILES: CCCCCCCCCCCCCCC(C)CC(C)CCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 12,14-Dimethyloctacosane is a natural product found in Coptotermes formosanus with data available.
Molecule SMILES: CC(=O)OCC1=CC2C(=O)C3(C=C(C)C(OC(=O)c4ccccc4NC(=O)c4ccccc4N)C3(O)C1O)C(C)CC1C2C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [(1S,4S,5S,6R,9S,10R,12R,14R)-7-(acetyloxymethyl)-5,6-dihydroxy-3,11,11,14-tetramethyl-15-oxo-4-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dienyl] 2-[(2-aminobenzoyl)amino]benzoate is a natural product found in Euphorbia leuconeura, Euphorbia cornigera, and Euphorbia milii with data available.
Molecule SMILES: O=C(CC1CC2c3cc(NC(=O)Nc4ccc(C(F)(F)F)cc4)ccc3OC2C(CO)O1)NCc1cc(F)ccc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-6-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-[(2,5-difluorophenyl)methyl]acetamide is a member of ureas.
Molecule SMILES: CC(=O)NC(CC(=O)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-Acetyl-DL-aspartic acid is an aspartic acid derivative.
Molecule SMILES: CC(=O)NC(CC(=O)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-Acetyl-DL-aspartic acid is a natural product found in Phaseolus vulgaris and Homo sapiens with data available.
Molecule SMILES: COc1c(O)cc2oc(-c3ccccc3)c(OC)c(=O)c2c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 5,7-Dihydroxy-3,6-dimethoxyflavone is a natural product found in Goniophlebium niponicum, Griffitharia pallescens, and other organisms with data available.
Molecule SMILES: CCC=CCC=CC(=O)NCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2,5-octadienoylglycine is a N-acyl-amino acid.
Molecule SMILES: CC1CCC(=C(C#N)c2nc(-c3cc4ccccc4oc3=O)cs2)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-(4-methylcyclohexylidene)-2-[4-(2-oxo-1-benzopyran-3-yl)-2-thiazolyl]acetonitrile is a terpene lactone.