IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: [N-]=[N+]=CC(=O)CCC(NC(=O)C(CCC(=O)C=[N+]=[N-])NC(=O)CCC(N)C(=O)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Azotomycin is an antineoplastic-antibiotic diazo analog of L-glutamine isolated from the bacterium Streptomyces ambofaciens.  Azotomycin inhibits glutamine-dependent enzymes involved in purine and pyrimidine biosynthesis, resulting in inhibition of DNA synthesis. (NCI04)
Molecule SMILES: C=C1C(C)C2C(Cc3ccccc3)NC(=O)C23C(OC(C)=O)C=CC(C)(O)C(=O)C(C)CC=CC3C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Cytochalasin d appears as needles or fluffy white powder. (NTP, 1992)
Molecule SMILES: COC1CN(C)C(=O)c2cc(NC(=O)Nc3c(C)noc3C)ccc2OCC(C)N(C)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 1-(3,5-dimethyl-4-isoxazolyl)-3-[(4S,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea is an azamacrocycle and a lactam.
Molecule SMILES: O=C(NC1C(OC(=O)c2cccnc2)OC(COC(=O)c2cccnc2)C(OC(=O)c2cccnc2)C1OC(=O)c1cccnc1)c1cccnc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Glunicate is a long-acting nicotinic acid derivative with antilipidemic activity. Glunicate has more prolonged activity on plasma free fatty acids and triglycerides, with longer lasting and more intense activity on plasma cholesterol than nicotinic acid or its derivative, niceritrol. In animal models glunicate showed dose-dependent protection of the arterial wall from atheromatous lesions and from cholesterol and collagen accumulation. These effects were independent of its effects on lowering plasma lipid levels.
Molecule SMILES: C=C1C(O)C(OC(=O)c2ccccc2)C=C(C)CCC2C(C(OC(C)=O)C(C=C(C)C)OC(C)=O)=COC(OC(C)=O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(1R,4aS,7E,9S,10S,11aR)-1-acetyloxy-4-[(1S,2R)-1,2-diacetyloxy-4-methylpent-3-enyl]-10-hydroxy-7-methyl-11-methylidene-4a,5,6,9,10,11a-hexahydro-1H-cyclonona[c]pyran-9-yl] benzoate is a natural product found in Clavularia inflata with data available.
Molecule SMILES: CC(C=C1C=C(C2CCC(O)(CO)CC2)C(=O)O1)C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-[4-[4-Hydroxy-4-(hydroxymethyl)cyclohexyl]-5-oxofuran-2-ylidene]-2-methylpropanamide is a natural product found in Paraconiothyrium brasiliense with data available.
Molecule SMILES: C[N+]1(C)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 1,1-dimethylaziridinium is an aziridinium ion.
Molecule SMILES: COC(=O)CC1C2(C)CC3(OC(=O)C(C)C)C(O)(C(=O)C4=C5CC(=O)OC(c6ccoc6)C5(C)CCC4C13C)C2OC(=O)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(1S,2R,5R,6R,13R,14S,15R,17R,18S)-6-(furan-3-yl)-13-hydroxy-18-(2-methoxy-2-oxoethyl)-1,5,15-trimethyl-17-(2-methylpropanoyloxy)-8,12-dioxo-7-oxapentacyclo[13.2.1.02,11.05,10.013,17]octadec-10-en-14-yl] 2-methylpropanoate is a natural product found in Xylocarpus moluccensis with data available.
Molecule SMILES: Nc1nc(C(=CCC(=O)O)C(=O)NC2C(=O)N3C(C(=O)O)=CCSC23)cs1.O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Molecule SMILES: O=C(NC1C=CC(CC(=O)N2CCOCC2)OC1CO)c1cccc(F)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-fluoro-N-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-(4-morpholinyl)-2-oxoethyl]-3,6-dihydro-2H-pyran-3-yl]benzamide is an organohalogen compound and a carbonyl compound.
Molecule SMILES: Cn1c(O)c(N=NC(=O)c2ccccc2O)c2ccccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-hydroxy-N-[(1-methyl-2-oxo-3-indolylidene)amino]benzamide is a member of salicylamides.
Molecule SMILES: CCC(CCCCCCCC(=O)Cc1cccc(O)c1)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 1-(3-Hydroxyphenyl)-10-phenyldodecan-2-one is a natural product found in Gluta usitata with data available.
Molecule SMILES: CC1OC(OC2C(Oc3c(-c4ccc(O)c(O)c4)oc4cc(O)cc(O)c4c3=O)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Calendoflavobioside is a member of flavonoids and a glycoside.
Molecule SMILES: CC1OC(OC2C(Oc3c(-c4ccc(O)c(O)c4)oc4cc(O)cc(O)c4c3=O)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Calendoflavobioside is a natural product found in Lysimachia nummularia, Cnidoscolus texanus, and other organisms with data available.
Molecule SMILES: CC(C1=C([O-])c2ccccc2C(=O)C1=O)C1=C([O-])c2ccccc2C(=O)C1=O.[Na+].[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Impatienolate is an organic sodium salt that is the disodium salt of impatienol. Isolated from the corolla of Impatiens balsamina, it exhibits inhibitory activity against COX-2. It has a role as a metabolite and a cyclooxygenase 2 inhibitor. It contains an impatienol(2-).
Molecule SMILES: CC1(C)CC2CC3(O)CC(=O)C(CO)=C3C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Xeromphalinone C is a natural product found in Xeromphalina with data available.
Molecule SMILES: COc1c(C2(O)COc3cc(O)cc(O)c3C2=O)ccc2c1C=CC(C)(C)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (3S)-3,5,7-trihydroxy-3-(5-methoxy-2,2-dimethylchromen-6-yl)-2H-chromen-4-one is a natural product found in Sophora fraseri with data available.
Molecule SMILES: C=C(C)C1(O)CCC2(C)CC=C(C)CCC=C(C)CCC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Isoedunol is a natural product found in Eunicea laciniata with data available.
Molecule SMILES: CC=C(C)C(=O)OC1CCC2(C)C(CC(O)C3(C)C2CCC24CC23CCC4C2CC(C3OC3(C)C)OC2O)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [(1S,2R,3R,5R,7S,10S,11R,14R,15S)-15-[(2R,3S,5R)-5-[(2R)-3,3-dimethyloxiran-2-yl]-2-hydroxyoxolan-3-yl]-3-hydroxy-2,6,6,10-tetramethyl-7-pentacyclo[12.3.1.01,14.02,11.05,10]octadecanyl] (E)-2-methylbut-2-enoate is a natural product found in Aglaia crassinervia with data available.
Molecule SMILES: COC1(CCC(C)COC2OC(CO)C(O)C(O)C2O)OC2CC3C4CC=C5CC(OC6OC(CO)C(OC7OC(C)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C2C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S,3R,4R,5R,6S)-2-[(2S,3R,4S,5R,6S)-4,5-dihydroxy-6-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[[(1S,2S,4S,6R,7S,8R,9S,12S,13R,16S)-6-methoxy-7,9,13-trimethyl-6-[(3R)-3-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-16-yl]oxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-2-methyloxan-3-yl]oxy-6-methyloxane-3,4,5-triol is a natural product found in Trachycarpus fortunei, Dioscorea pseudojaponica, and other organisms with data available.
Molecule SMILES: CC1CCC2(OC1)OC1CC3C4C(O)C=C5CC(OC6OC(CO)C(O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Sansevierin A is a natural product found in Sansevieria ehrenbergii with data available.
Molecule SMILES: CCC(C)C1NC(=O)C(NC(=O)C(C)C)C(C)OC(=O)C(COC(=O)CNC(C)=O)NC(=O)C(C(C)O)NC(=O)C(Cc2ccccc2)N(C)C(=O)C(c2ccc(OC)cc2)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: isobutyryl-DL-xiThr(1)-DL-xiIle-DL-nTyr(Me)-DL-N(Me)Phe-DL-xiThr-DL-Ser(2)-(1).Ac-Gly-(2) is a natural product found in Streptomyces with data available.
Molecule SMILES: COc1ccc(NC(=S)NC(NC(=O)c2cccc(Cl)c2)C(Cl)(Cl)Cl)c([N+](=O)[O-])c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-chloro-N-[2,2,2-trichloro-1-[[(4-methoxy-2-nitroanilino)-sulfanylidenemethyl]amino]ethyl]benzamide is an aromatic ether and a C-nitro compound.
Molecule SMILES: CCCCCC=CCC=CCC=CCC=CCC=CCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCC=CCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: PA(22:5(4Z,7Z,10Z,13Z,16Z)/22:1(13Z)) is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: O=C(O)C1=NC(C(=O)O)CC(C=CN2C3=CC(=O)C(=O)C=C3CC2C(=O)O)=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S)-4-[(E)-2-[(2S)-2-carboxy-5,6-dioxo-2,3-dihydroindol-1-yl]ethenyl]-2,3-dihydropyridine-2,6-dicarboxylic acid is a natural product found in Beta vulgaris with data available.
Molecule SMILES: CC(=CCCC(C)C1CCC2(C)C3CC=C4C(CCC(OC5OC(CO)C(O)C(O)C5O)C4(C)C)C3(C)C(O)CC12C)COC1OC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Scandenoside R7 is a natural product found in Hemsleya panacis-scandens with data available.
Molecule SMILES: C=CCCCC(C)C1CCC2C3CCC4CC(OS(=O)(=O)O)C(OS(=O)(=O)O)CC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Halistanol disulfate B is a natural product found in Pachastrella with data available.
Molecule SMILES: O=C(O)c1cc(=O)oc2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Coumarin-4-carboxylic acid is a member of coumarins.
Molecule SMILES: CCCCCC=CCC=CCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCCCC)COP(=O)(O)OP(=O)(O)OCC1OC(n2ccc(N)nc2=O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: CDP-1-stearoyl-2-linoleoyl-sn-glycerol is a CDP-diacylglycerol in which the phosphatidyl acyl groups at positions 1 and 2 are specified as stearoyl and linoleoyl respectively. It has a role as a human metabolite. It is functionally related to an octadecanoic acid and a linoleic acid. It is a conjugate acid of a CDP-1-stearoyl-2-linoleoyl-sn-glycerol(2-).
Molecule SMILES: CCCCC(=O)OCC(=O)C1C(C)CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Diflucortolone valerate is a corticosteroid hormone.
Molecule SMILES: CCC=CCC=CCC=CCC=CCCCCC(=O)OCC(O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: MG(18:4(6Z,9Z,12Z,15Z)/0:0/0:0) is a natural product found in Sargassum sagamianum with data available.
Molecule SMILES: CC1OC(OC2C(OC3C(OC4CCC5(C)C(CCC6(C)C5CC=C5C7CC(C)(C)CC(O)C7(C)C(=O)CC56C)C4(C)C)OC(C(=O)O)C(O)C3O)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 3beta-[[2-O-(2-O-alpha-L-Rhamnopyranosyl-beta-D-galactopyranosyl)-beta-D-glucurono pyranosyl]oxy]-22alpha-hydroxyoleana-12-ene-16-one is a natural product found in Stylosanthes erecta with data available.
Molecule SMILES: NCCCC(=O)NC(Cc1cnc[nH]1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Homocarnosine is a histidine derivative that is histidine in which one of the hydrogens attached to the alpha-amino group has been replaced by a 4-aminobutanoyl group. It has a role as a metabolite. It is a histidine derivative, a N-acyl-amino acid and a member of imidazoles. It is functionally related to a gamma-aminobutyric acid.
Molecule SMILES: O=C(O)c1cc(=O)c2c([nH]1)C(O)C(O)C=C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 7,8-dihydro-7,8-dihydroxykynurenic acid is the 7,8-dihydro-7,8-dihydroxy derivative of kynurenic acid. It is functionally related to a kynurenic acid. It is a conjugate acid of a 7,8-dihydro-7,8-dihydroxykynurenate.
Molecule SMILES: CC(C)C1=Cc2c(cc3c(cc2=O)C(C)(C)C(O)C=C3)C(=O)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 13-Hydroxy-12,12-dimethyl-6-propan-2-yltricyclo[9.4.0.03,8]pentadeca-1,3(8),6,10,14-pentaene-4,5,9-trione is a natural product found in Taxus cuspidata with data available.
Molecule SMILES: CC(=O)CCC1C2CC(C(C)(C)O)C(=O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Bicyclo(4.1.0)heptan-3-one, 4-(1-hydroxy-1-methylethyl)-1-methyl-7-(3-oxobutyl)-, (1S,4S,6R,7R)- is a natural product found in Curcuma zedoaria with data available.
Molecule SMILES: O=C([O-])CC(O)C(=O)[O-].[H+].[H+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Malic acid is a natural product found in Prunus mume, Eupatorium cannabinum, and other organisms with data available.
Molecule SMILES: CNCC1OCCCCC(C)Oc2ccc(NC(=O)Nc3cccc4ccccc34)cc2C(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 1-[(3R,9S,10S)-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-9-(methylaminomethyl)-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]-3-(1-naphthalenyl)urea is an azamacrocycle and a lactam.
Molecule SMILES: COc1c(C)c(OCC=C(C)C)cc2c1C(=O)OC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 4-Methoxy-5-methyl-6-(3-methyl-2-butenyloxy)isobenzofuran-1,3-dione is a natural product found in Pestalotiopsis photiniae with data available.
Molecule SMILES: CC(C)(C)c1ccc(OCCNC(=O)Cc2ccc(F)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: N-[2-(4-tert-butylphenoxy)ethyl]-2-(4-fluorophenyl)acetamide is a member of acetamides.
Molecule SMILES: CC1OC(OC2C(O)C(OCCc3ccc(O)c(O)c3)OC(COC3OC(CO)C(O)C(O)C3O)C2OC(=O)C=Cc2ccc(O)cc2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(4-hydroxyphenyl)prop-2-enoate is a natural product found in Cistanche tubulosa and Cistanche phelypaea with data available.
Molecule SMILES: C=CC(C)(C)c1c(O)cc2oc3c(CC=C(C)C)c(O)c(O)cc3c(=O)c2c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: cudraxanthone L is a natural product found in Maclura tricuspidata with data available.
Molecule SMILES: COc1cc2c(cc1OC)C(C)N(C(=S)Nc1ccc(F)cc1)CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1S)-N-(4-fluorophenyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline-2-carbothioamide is a member of isoquinolines.
Molecule SMILES: CC(C)OP(=O)(OC(C)C)C(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)P(=O)(OC(C)C)OC(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Apomine has been used in trials studying the treatment of Osteoporosis and Unspecified Adult Solid Tumor, Protocol Specific.
Molecule SMILES: CC(C)OP(=O)(OC(C)C)C(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)P(=O)(OC(C)C)OC(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Apomine is a 1,1-bisphosphonate ester with potential antineoplastic and hypocholesterolemic activities. SR-45023A binds to hydroxyapatite crystals in the bone matrix where it inhibits enzymatic activity of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which is required for the formation of mevalonate, the precursor of cholesterol. Consequently, shortage of mevalonate impedes the synthesis of downstream isoprenoids that are essential for protein prenylation. This leads to the loss of activity of proteins involved in osteoclast function and cellular proliferation, such as Ras and Rho, leading to an inhibition of cellular proliferation, and induction of osteoclasts apoptosis. In addition, SR-45023A activates the farnesoid X activated receptor (FXR), a member of the nuclear hormone superfamily implicated in cholesterol metabolism and bile acid transport and may play a role in this agent's antineoplastic effect.
Molecule SMILES: COC(=O)OC12C(=O)NC(Cc3ccccc3)C1C(C)C1(C)OC1C2C=CCC(C)C(=O)C(C)(O)CC(OC)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(1aR,2R,2aR,5R,5aR,6R,6aS)-5-benzyl-2-[(E,4R,6S)-6-hydroxy-8,8-dimethoxy-4,6-dimethyl-5-oxooct-1-enyl]-6,6a-dimethyl-3-oxo-1a,2,4,5,5a,6-hexahydrooxireno[2,3-f]isoindol-2a-yl] methyl carbonate is a natural product found in Aspergillus flavipes with data available.
Molecule SMILES: CC(=O)C1=C(O)C(Cc2c[nH]c3cccc(CC=C(C)C)c23)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2H-Pyrrol-2-one, 3-acetyl-1,5-dihydro-4-hydroxy-5-((4-(3-methyl-2-butenyl)-1H-indol-3-yl)methyl)-, (S)- is a natural product found in Penicillium aurantiogriseum and Penicillium cyclopium with data available.
Molecule SMILES: O=C(O)c1ccc([O-])c(Br)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-bromo-4-hydroxybenzoate is a monohydroxybenzoate that is the conjugate base of 3-bromo-4-hydroxybenzoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. It is functionally related to a benzoate. It is a conjugate base of a 3-bromo-4-hydroxybenzoic acid.
Molecule SMILES: COc1c2c(cc3ccoc13)C(=O)c1cc(C(C)(C)O)oc1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 7-(2-Hydroxypropan-2-yl)-10-methoxy-[1]benzofuro[5,6-f][1]benzofuran-5,9-dione is a natural product found in Plumbago zeylanica with data available.
Molecule SMILES: CNCC1Oc2c(NC(=O)c3nc4ccccc4s3)cccc2C(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-1,3-benzothiazole-2-carboxamide is a member of benzothiazoles.