IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ability to cross the placental barrier during pregnancy which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. Additional adverse effects such as necrosis, purple toe syndrome, osteoporosis, valve and artery calcification, and drug interactions have also been documented with warfarin use. Warfarin does not actually affect blood viscosity, rather, it inhibits vitamin-k dependent synthesis of biologically active forms of various clotting factors in addition to several regulatory factors.
Molecule SMILES: CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Warfarin is a Vitamin K Antagonist. The mechanism of action of warfarin is as a Vitamin K Inhibitor.
Molecule SMILES: CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Warfarin is a synthetic anticoagulant. Warfarin inhibits the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors, which include Factors II, VII, IX and X, and the anticoagulant proteins C and S. This inhibition results in a sequential depression of Factors VII, IX, X and II activities. Vitamin K is an essential cofactor for the post ribosomal synthesis of the vitamin K dependent clotting factors. The vitamin promotes the biosynthesis of gamma-carboxyglutamic acid residues in these proteins which are essential for biological activity.
Molecule SMILES: CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ability to cross the placental barrier during pregnancy which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. Additional adverse effects such as necrosis, purple toe syndrome, osteoporosis, valve and artery calcification, and drug interactions have also been documented with warfarin use. Warfarin does not actually affect blood viscosity, rather, it inhibits vitamin-k dependent synthesis of biologically active forms of various clotting factors in addition to several regulatory factors.
Molecule SMILES: O=C(Oc1cc(O)c2c(c1)OC(c1ccc(O)c(O)c1)C(O)C2)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Catechin 7-O-gallate is a natural product found in Sanguisorba officinalis, Rhynchosia volubilis, and other organisms with data available.
Molecule SMILES: C=C1C(=O)OC2C=C(C)C3(O)C=CC(C)(CC(OC(=O)C(C)=CC)C12)O3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Helivypolide D is a natural product found in Helianthus annuus with data available.
Molecule SMILES: CC(C)(O)CCC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5Alpha-20-Hydroxyecdysone is a natural product found in Rhaponticum carthamoides with data available.
Molecule SMILES: C=C1C2CC(OC(C)=O)C3C(C2)(C(=O)OCC32C(OC(C)=O)CCC(C)(C)C2COC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(1S,1'R,3'S,5R,6S,7S,9S,11R)-3',7-diacetyloxy-11-hydroxy-6',6'-dimethyl-10-methylidene-2-oxospiro[3-oxatricyclo[7.2.1.01,6]dodecane-5,2'-cyclohexane]-1'-yl]methyl acetate is a natural product found in Isodon rubescens with data available.
Molecule SMILES: CC1=CCC23CC1CC2CCC1C(C)(C)CCCC13C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2,6,6,13-Tetramethyltetracyclo[10.3.1.01,10.02,7]hexadec-13-ene is a natural product found in Oryza sativa with data available.
Molecule SMILES: O=C(O)c1ccc(C(F)(F)F)cc1-c1ccc2c(c1)OCC(Cc1ccccc1)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: CP-195,543 has been used in trials studying the treatment of Arthritis, Rheumatoid.
Molecule SMILES: CCC(=O)N1CC(C)C(OC)CN(C)C(=O)c2cc(NC(=O)C3CC3)ccc2OCC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: N-[(4R,7S,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-(1-oxopropyl)-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]cyclopropanecarboxamide is an azamacrocycle and a lactam.
Molecule SMILES: CC(C)C(NC(=O)C(NC(=O)NC(Cc1ccc(O)cc1)C(=O)O)C1CCNC(N)=N1)C(=O)NC(C=O)Cc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S)-2-[[(1S)-1-[(4R)-2-amino-1,4,5,6-tetrahydropyrimidin-4-yl]-2-[[(2S)-3-methyl-1-oxo-1-[[(2S)-1-oxo-3-phenylpropan-2-yl]amino]butan-2-yl]amino]-2-oxoethyl]carbamoylamino]-3-(4-hydroxyphenyl)propanoic acid is a natural product found in Streptomyces mobaraensis with data available.
Molecule SMILES: CC=C(C)C(=O)OC1C=C(CO)C(OC(=O)C(C)=CC)C(OC(C)=O)C1C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-(Hydroxymethyl)-5alpha-acetoxy-6beta-isopropyl-2-cyclohexene-1beta,4alpha-diol 1,4-bis[(E)-2-methyl-2-butenoate] is a natural product found in Sphaeranthus suaveolens with data available.
Molecule SMILES: CC(=O)NC(CCS(C)=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-Acetylmethionine sulfoxide is a N-acyl-amino acid.
Molecule SMILES: CC(C)(O)C(O)CCC(C)(O)C1CCC(C)(C2CCC(C3(C)CCC4OC(C)(C)C(Br)CCC4(C)O3)O2)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Aurilol is a natural product found in Dolabella auricularia with data available.
Molecule SMILES: Oc1ccc(-c2oc3cc(O)cc4c3c2-c2cc(O)cc(O)c2C(c2ccc(O)cc2)C4O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: malibatol A is a natural product found in Hopea utilis and Vitis vinifera with data available.
Molecule SMILES: CC1=CCN(CCCCNC(=O)C=Cc2ccccc2)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 1-[4-(3-Phenylacryloylamino)butyl]-3-methyl-3-pyrroline-2-one is a natural product found in Aglaia rubiginosa with data available.
Molecule SMILES: OCCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is a natural product found in Cordyceps pruinosa, Micromeles japonica, and Isaria japonica with data available.
Molecule SMILES: CC(NC(=O)CC1CCC(NC(=O)Nc2ccc3c(c2)OCO3)C(CO)O1)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2-[(2S,5R,6R)-5-[[(1,3-benzodioxol-5-ylamino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-[(1S)-1-phenylethyl]acetamide is a C-glycosyl compound.
Molecule SMILES: CC(C=CC(=O)O)=CC(C)C(=O)c1ccc(N(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (4Z,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoic acid is a natural product found in Streptomyces with data available.
Molecule SMILES: CCCCCCCCCCCCCC(O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)([O-])[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (R)-3-hydroxypalmitoyl-CoA(4-) is a 3-hydroxy fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (R)-3-hydroxypalmitoyl-CoA. It is a (R)-3-hydroxyacyl-CoA(4-), a 3-hydroxy fatty acyl-CoA(4-) and an 11,12-saturated fatty acyl-CoA(4-). It is a conjugate base of a (R)-3-hydroxypalmitoyl-CoA.
Molecule SMILES: CC1CC(CO)=CCC(=O)OC(C)CC=CC(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Bartallol is a natural product found in Cytospora with data available.
Molecule SMILES: C=C(C)C1CCC2(C(=O)OC)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Betulinic acid methyl ester is a triterpenoid.
Molecule SMILES: C=C(C)C1CCC2(C(=O)OC)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Methyl betulinate is a natural product found in Ixeridium gracile, Euptelea polyandra, and other organisms with data available.
Molecule SMILES: CC(C)C(=O)OC1C(=O)c2c(O)cc(O)cc2OC1c1cccc(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(2R,3R)-5,7-dihydroxy-2-(3-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl] 2-methylpropanoate is a natural product found in Flourensia retinophylla with data available.
Molecule SMILES: C=CC1(C)CC(=O)C2C(C)(CCC3C(C)(C)CCCC32C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (3R,4aR,6aR,10aS,10bR)-3-ethenyl-3,4a,7,7,10a-pentamethyl-2,5,6,6a,8,9,10,10b-octahydrobenzo[f]chromen-1-one is a natural product found in Plectranthus barbatus with data available.
Molecule SMILES: COc1ccc(C2CC(=O)c3c(O)cc(OC4OC(COC5OC(C)C(O)C(O)C5O)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)cc3O2)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one is a natural product found in Alhagi maurorum with data available.
Molecule SMILES: C=C1CCC2C(C)(C)C(O)CCC2(C)C1CCC(C)=CC(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 3-Methyl-5-[(1S,4aalpha)-2-methylene-5,5,8abeta-trimethyl-6beta-hydroxydecahydronaphthalene-1beta-yl]-2-pentenoic acid methyl ester is a natural product found in Copaifera paupera with data available.
Molecule SMILES: CCc1c(OC)cc2c(c1O)C(=O)C1C3c4c(OC)cc(=O)oc4CC2(O)C1(O)OC3CC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 10,17-Diethyl-1,12,16-trihydroxy-7,18-dimethoxy-4,11-dioxapentacyclo[10.8.0.03,8.09,13.015,20]icosa-3(8),6,15,17,19-pentaene-5,14-dione is a natural product found in Delitschia with data available.
Molecule SMILES: ClCC1CO1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (S)-epichlorohydrin is an epichlorohydrin. It is functionally related to a (R)-1,2-epoxypropane. It is an enantiomer of a (R)-epichlorohydrin.
Molecule SMILES: CC1(O)CSc2c(C=O)c3ccccc3n21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1S)-1-hydroxy-1-methyl-2H-[1,3]thiazolo[3,2-a]indole-4-carbaldehyde is a natural product found in Pseudomonas cichorii and Brassica rapa with data available.
Molecule SMILES: COc1ccc(NC(=O)C(=O)NNC(=O)C(C)Oc2ccc(Cl)cc2Cl)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2-[[2-(2,4-dichlorophenoxy)-1-oxopropyl]hydrazo]-N-(4-methoxyphenyl)-2-oxoacetamide is an amino acid amide.
Molecule SMILES: CCCCCC(C)CC(C)C=C(C)C(=O)C(C)C(=O)CC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (E,4R,8S,10S)-4,6,8,10-tetramethylpentadec-6-ene-3,5-dione is a natural product found in Siphonaria pectinata with data available.
Molecule SMILES: CC1OC2OC(c3ccoc3)CC2(c2cccc3c2COC3=O)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 4-[(2R,3S,3aR,5R,6aR)-5-(furan-3-yl)-2,3-dimethyl-3,4,5,6a-tetrahydro-2H-furo[2,3-b]furan-3a-yl]-3H-2-benzofuran-1-one is a natural product found in Salvia rhyacophila with data available.
Molecule SMILES: Oc1cccc2c1C(O)CC(O)C21Oc2cccc3cccc(c23)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (1R,3R)-spiro[2,3-dihydro-1H-naphthalene-4,3'-2,4-dioxatricyclo[7.3.1.05,13]trideca-1(12),5,7,9(13),10-pentaene]-1,3,8-triol is a natural product found in Strychnos angustiflora with data available.
Molecule SMILES: CC=C(C)C(OC(C)=O)C(C)c1cc(O)c2c(c1O)OC1(C)CCC3OC(C(C)(C)O)CC(O)C3(C)C1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Stemphone G is a natural product found in Aspergillus with data available.
Molecule SMILES: OCC1OC(Oc2cc(O)c3c(c2)OC(c2ccc(O)cc2)C(O)C3)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2S,3R,4S,5S,6R)-2-[[(2R,3R)-3,5-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a natural product found in Pinalia floribunda and Wisteria floribunda with data available.
Molecule SMILES: Cc1noc(C)c1NC(=O)NC1CCC(CCNC(=O)C2CCOCC2)OC1CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N-[2-[(2R,5S,6R)-5-[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]ethyl]-4-oxanecarboxamide is a C-glycosyl compound.
Molecule SMILES: CC(=O)NC1C(OC2C(O)C(CO)OC(OC3C(CO)OC(O)C(O)C3O)C2O)OC(CO)C(OC2OC(CO)C(O)C(O)C2OC2OC(C)C(O)C(O)C2O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-Glcp is a linear amino pentasaccharide consisting of alpha-fucosyl, beta-galactosyl, beta-glucosaminyl, beta-galactosyl and glucose units connected via sequential (1->2)-, (1->4)-, (1->3)- and (1->4)-linkages. It is an amino pentasaccharide and a glucosamine oligosaccharide.
Molecule SMILES: CC(NC(=O)CC1C=CC(NC(=O)c2cccnc2)C(CO)O1)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: N-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]-3,6-dihydro-2H-pyran-3-yl]-3-pyridinecarboxamide is a pyridinecarboxamide. It is functionally related to a nicotinamide.
Molecule SMILES: CN1CC(C(=O)NC2(C)OC3(O)C4CCCN4C(=O)C(Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)CC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Ergotamine is a peptide ergot alkaloid that is dihydroergotamine in which a double bond replaces the single bond between positions 9 and 10. It has a role as a non-narcotic analgesic, a vasoconstrictor agent, a serotonergic agonist, an alpha-adrenergic agonist, a mycotoxin and an oxytocic. It is a conjugate base of an ergotamine(1+).
Molecule SMILES: CN1CC(C(=O)NC2(C)OC3(O)C4CCCN4C(=O)C(Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)CC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Molecule SMILES: CN1CC(C(=O)NC2(C)OC3(O)C4CCCN4C(=O)C(Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)CC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Ergotamine is an Ergotamine Derivative.
Molecule SMILES: CN1CC(C(=O)NC2(C)OC3(O)C4CCCN4C(=O)C(Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)CC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Ergotamine is a naturally occurring ergot alkaloid with vasoconstrictor and analgesic property. Ergotamine selectively binds and activates serotonin (5-HT) 1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, thereby resulting in vasoconstriction and reducing the blood flow in cerebral arteries that may lead to relieve of vascular headaches. This agent also selectively binds to alpha-adrenergic receptors, thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins, which also contributes to the relief of headaches. Furthermore, the activation of 5-HT1D receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.
Molecule SMILES: CN1CC(C(=O)NC2(C)OC3(O)C4CCCN4C(=O)C(Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)CC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ergotamine is a natural product found in Cenchrus echinatus, Claviceps fusiformis, and other organisms with data available.
Molecule SMILES: CN1CC(C(=O)NC2(C)OC3(O)C4CCCN4C(=O)C(Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)CC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Ergotamine is only found in individuals that have used or taken this drug. It is a vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders. Ergotamine acts on migraine by one of two proposed mechanisms: 1) activation of 5-HT<sub>1D</sub> receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leads to vasoconstriction, which correlates with the relief of migraine headache, and 2) activation of 5-HT<sub>1D</sub> receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.
Molecule SMILES: COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Ubiquinone-6 is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Ubiquinone 6 is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: COCCNC(=O)CC1CCC2C(COCC(O)CN2C(=O)c2cc(Cl)cc(Cl)c2)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-[(3R,6aS,8S,10aS)-1-[(3,5-dichlorophenyl)-oxomethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocin-8-yl]-N-(2-methoxyethyl)acetamide is an organohalogen compound and a carbonyl compound.