IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(C)C(O)(C(=O)OCC1=CCN2CCC(O)C12)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Intermedine is a carboxylic ester compound formed from condensation between retronecine and (2S,3R)-2,3-dihydroxy-2-isopropylbutanoic acid. It is a member of pyrrolizines, an azabicycloalkane and a carboxylic ester.
Molecule SMILES: CC(C)C(O)(C(=O)OCC1=CCN2CCC(O)C12)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Intermedine is a natural product found in Eupatorium cannabinum, Chromolaena odorata, and other organisms with data available.
Molecule SMILES: Oc1ccc2c(c1)CCc1ccc(cc1)Oc1cc(ccc1Oc1cc3c(cc1O)CCc1ccc(cc1)Oc1cc(ccc1O)CCc1ccc-3c(O)c1)CCc1ccc-2c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 4-[(5,24-Dihydroxy-14-oxapentacyclo[20.2.2.210,13.115,19.02,7]nonacosa-1(24),2(7),3,5,10(29),11,13(28),15,17,19(27),22,25-dodecaen-16-yl)oxy]-14-oxapentacyclo[20.2.2.210,13.115,19.02,7]nonacosa-1(24),2,4,6,10(29),11,13(28),15,17,19(27),22,25-dodecaene-5,16,24-triol is a natural product found in Blasia pusilla with data available.
Molecule SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCC(=O)C=CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: OKODiA-PA is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: CC(C)=C1CC2=C(C(=O)C3C4C(=O)C5=C(CC(=C(C)C)C(=O)CC5C)C4(C)C23C)C(C)CC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1S,2S,8S,11R,12R,15S)-1,2,8,15-tetramethyl-5,18-di(propan-2-ylidene)pentacyclo[10.8.0.02,11.03,9.014,20]icosa-3(9),14(20)-diene-6,10,13,17-tetrone is a natural product found in Xylopia vielana with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(COC2OC(C)C(O)C(O)C2O)C(OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4OC4OC(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4NC(C)=O)C(O)C(OC4OC(CO)C(OC5OC(CO)C(OC6OC(CO)C(O)C(O)C6O)C(O)C5NC(C)=O)C(O)C4OC4OC(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4NC(C)=O)C3O)C(O)C2NC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-Acetamido-5-[(3S,4S,5R,6R)-6-[[(2S,3S,4S,5S,6R)-3-[(2S,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2R,3S,4S,5S,6R)-3,5-bis[[(2S,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy]-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxyoxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,4-dihydroxy-6-[[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl]acetamide is an amino sugar.
Molecule SMILES: CC1=C2C=CCCC(C)C2CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (+)-Isoclavukerin is a natural product found in Cespitularia with data available.
Molecule SMILES: CC=C1CN2C3CC45c6cc(OC)c(OC)cc6NC4(O3)C2CC1C5C(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: methyl (1R,9R,11S,14E,15R,17S,19S)-14-ethylidene-5,6-dimethoxy-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate is a natural product found in Alstonia macrophylla with data available.
Molecule SMILES: CCC(C)C1C(=O)N(C)C(C(C)CC)C(=O)NCC(=O)N(C)C(C(C)C)C(=O)NC(Cc2ccc(OC)cc2)C(=O)OC(C)C(=O)N2CCCCC2C(=O)N(C)C(C(C)C)C(=O)NC(C(C)C)C(=O)N(C)C(CC(=O)OC(C)(C)C)C(=O)N1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: SDZ 280-446 is a novel semi-synthetic derivative of cyclosporin and a cyclodepsipeptide with chemo-sensitizing activity. SDZ 280-446 is one of the drug resistance-modifying agents that inhibit P-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activities of some drugs in drug-resistant tumor cells.
Molecule SMILES: CC(=O)Nc1ccc(C=NNC(=O)CC2CCCCC2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N-[(4-acetamidophenyl)methylideneamino]-2-cyclohexylacetamide is an anilide and a member of acetamides.
Molecule SMILES: CCC(=O)OC1C(O)CNC1Cc1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(2S,3S,4S)-4-hydroxy-2-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl] propanoate is a natural product found in Streptomyces with data available.
Molecule SMILES: CC(C)=CCc1c(O)cc(O)c2c(=O)c(OC3OC(C)C(O)C(O)C3OC3OC(C)C(O)C(O)C3O)c(-c3ccc(O)cc3)oc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Noranhydroicaritin 3-rhamnosyl-(1->2)-rhamnoside is a glycoside and a member of flavonoids.
Molecule SMILES: NCSCCC(S)CCCCC(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: S(8)-aminomethyldihydrolipoamide is a S-substituted dihydrolipoamide. It has a role as a Saccharomyces cerevisiae metabolite.
Molecule SMILES: NCSCCC(S)CCCCC(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: S(8)-aminomethyldihydrolipoamide is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: NCSCCC(S)CCCCC(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 8-[(Aminomethyl)sulfanyl]-6-sulfanyloctanamide is a natural product found in Homo sapiens with data available.
Molecule SMILES: COC(C)(C)C(O)COc1c2occc2cc2ccc(=O)oc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 9-[(2R)-2-hydroxy-3-methoxy-3-methylbutoxy]furo[3,2-g]chromen-7-one is a natural product found in Prangos pabularia with data available.
Molecule SMILES: C=C1CC(OC(=O)Cc2ccc(O)cc2)C2C(=C)C(=O)OC2C2C(=C)C(OC3OC(CO)C(O)C(O)C3O)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(3aS,4R,6aS,8S,9aS,9bS)-3,6,9-trimethylidene-2-oxo-8-[(2S,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-4-yl] 2-(4-hydroxyphenyl)acetate is a natural product found in Crepis tingitana with data available.
Molecule SMILES: CC=CCCCC(C)C(=O)C1=C(O)C(=CC)N(C)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Penicillenol D1 is a natural product found in Penicillium citrinum with data available.
Molecule SMILES: O=C1CCc2cc(S(=O)(=O)Nc3ccc4c(c3)OCCO4)ccc2N1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonamide is a member of quinolines.
Molecule SMILES: CC1CCCCC(CCCCBr)c2c(O)cc(cc2O)C(OC(N)=O)C(C)CCCCC(CCCC(Br)Br)c2c(O)cc(cc2O)C1OC(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Carbamidocyclophane P is a natural product found in Nostoc with data available.
Molecule SMILES: O=C1CC(c2ccc(OC3OC(CO)C(O)C(O)C3O)cc2)Oc2cc(OC3OC(CO)C(O)C(O)C3O)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Glucoliquiritin is a member of flavonoids and a glycoside.
Molecule SMILES: CC1=NC(C(=O)O)Cc2c1[nH]c1cc(O)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 7-hydroxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole-3-carboxylic acid is a natural product found in Cortinarius brunneus var. brunneus with data available.
Molecule SMILES: COc1ccc(OC(=O)N(C)CC2OCc3ccccc3-c3ccccc3C(=O)N(C(C)CO)CC2C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: LSM-10605 is a member of methoxybenzenes.
Molecule SMILES: CC1CC2OC(=O)CC13CC(O)C(C)(O)C(C)(COC(=O)c1ccccc1)C23O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (3,4,6-Trihydroxy-4,5,11-trimethyl-9-oxo-8-oxatricyclo[5.3.2.01,6]dodecan-5-yl)methyl benzoate is a natural product found in Illicium dunnianum and Illicium floridanum with data available.
Molecule SMILES: COCC1=CC2OC(=O)C(C)C2(O)C(OC(C)=O)C2C3(CO3)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C2(C)C(OC(C)=O)C=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: juncenolide D is a natural product found in Junceella juncea with data available.
Molecule SMILES: CCC=CC=CC1(C)OC(CC(C)O)=CC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (2S)-2-hexa-1,3-dienyl-5-[(2S)-2-hydroxypropyl]-2-methylfuran-3-one is a natural product found in Aspergillus terreus with data available.
Molecule SMILES: C=C1C(=O)OC2CC(C)C(CCC(C)OC(=O)C(C)CC)=CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 4-[(3aR,7S,8aR)-7-methyl-3-methylidene-2-oxo-4,7,8,8a-tetrahydro-3aH-cyclohepta[b]furan-6-yl]butan-2-yl 2-methylbutanoate is a natural product found in Carpesium macrocephalum with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(COS(=O)(=O)O)C(OC2OC(COS(=O)(=O)O)C(O)C(OS(=O)(=O)O)C2O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3,6-di-O-sulfo-beta-D-galactosyl-(1->4)-6-O-sulfo-N-acetyl-beta-D-glucosamine is an amino disaccharide that consists of 6-O-sulfo-N-acetyl-beta-D-glucosamine having a 3,6-di-O-sulfo-beta-D-galactosyl residue attached at position 4. It has a role as an epitope. It is an amino disaccharide and an oligosaccharide sulfate.
Molecule SMILES: C=C1C(O)C2OC23CC2C=C(C)C(=O)C2C13C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Creolophin C is a natural product found in Hericium cirrhatum with data available.
Molecule SMILES: COc1c(OC2OC(C)C(O)C(OC(C)=O)C2O)cc2oc(-c3ccc(O)c(O)c3)c(OC3OC(C)C(OC(C)=O)C(O)C3O)c(=O)c2c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: [6-[7-(4-Acetyloxy-3,5-dihydroxy-6-methyloxan-2-yl)oxy-2-(3,4-dihydroxyphenyl)-5-hydroxy-6-methoxy-4-oxochromen-3-yl]oxy-4,5-dihydroxy-2-methyloxan-3-yl] acetate is a natural product found in Kalanchoe laciniata with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)Cc2cc(NC(=O)CCC(F)(F)F)ccc2OC1CN(C)Cc1ccc2c(c1)OCO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: N-[(2S,3S)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]-4,4,4-trifluorobutanamide is a member of benzodioxoles.
Molecule SMILES: CC(=O)OC1C(C)C=C(C)C(O)C(C)C=CC(=O)N(C)C(Cc2ccccc2)C(=O)OC(C)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Torrubiellutin C is a natural product found in Conoideocrella luteorostrata with data available.
Molecule SMILES: Cc1cc(C)c2c(c1O)C(=O)OC(C)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Versicoisochromane A is a natural product found in Aspergillus versicolor with data available.
Molecule SMILES: COc1ccc(C2CC(OC(C)=O)CC3CCCCN32)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S,9abeta)-2alpha-Acetoxy-4beta-(3-hydroxy-4-methoxyphenyl)-1,2,3,6,7,8,9,9a-octahydro-4H-quinolizine is a natural product found in Heimia salicifolia with data available.
Molecule SMILES: O=COCCOC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ethylene glycol diformate appears as a water-white liquid. More dense than water. May be toxic by ingestion. Used in embalming fluids.
Molecule SMILES: C=C1C(=O)OC2C=C(C)CCC=C(CO)CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (3aS,6E,10E,11aS)-6-(hydroxymethyl)-10-methyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2-one is a natural product found in Clibadium surinamense with data available.
Molecule SMILES: CN(CC1CCCCC1)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-(Cyclohexylmethyl)-N-methylbenzenamine is a member of benzenes.
Molecule SMILES: CC(C)=CCCC(C)(O)C(O)CCC(C)=CCOCC1OC(N2CCC(=O)NC2=O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Farneside B is a sesquiterpenoid.
Molecule SMILES: Nc1ncnc2c1ncn2C1OC(COP(=O)([O-])[O-])C(O)C1OP(=O)([O-])[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Adenosine 2',5'-bisphosphate(4-) is major species at pH 7.3 It is a conjugate base of an adenosine 2',5'-bisphosphate.
Molecule SMILES: O=CC(O)CS(=O)(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: D-3-sulfolactaldehyde(1-) is a 3-sulfolactaldehyde(1-) in which the stereocentre at position 3 has R-configuration. It is a conjugate base of a D-3-sulfolactaldehyde. It is an enantiomer of a L-3-sulfolactaldehyde(1-).
Molecule SMILES: CC(C)=CCCC(C)(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3CCC(O)C(C)(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S,3R,4S,5S,6R)-2-[2-(3,12-dihydroxy-4,4,8,14-tetramethyl-1,2,3,5,6,7,9,10,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)-6-methylhept-5-en-2-yl]oxy-6-[[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxane-3,4,5-triol is a natural product found in Gynostemma pentaphyllum with data available.
Molecule SMILES: O=c1cccc(C2CC(CO)C3CCCCN3C2)[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 6-[1-(hydroxymethyl)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-3-yl]-1H-pyridin-2-one is a natural product found in Sophora velutina and Sophora flavescens with data available.
Molecule SMILES: CC(=O)OC1CCC23CC24CCC2(C)C(C(C)CCC=C(C)C)CCC2(C)C4CCC3C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(1S,3R,6S,7S,8S,11S,12S,15R,16R)-7,12,16-trimethyl-15-[(2R)-6-methylhept-5-en-2-yl]-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl] acetate is a natural product found in Goniophlebium mengtzeense with data available.
Molecule SMILES: c1cncc(C2=NCCC2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Myosmine is a member of the class of pyridines that is pyridine substituted by a 3,4-dihydro-2H-pyrrol-5-yl group at position 3. It is an alkaloid found in tobacco plants and exhibits genotoxic effects. It has a role as a plant metabolite, an EC 1.14.14.14 (aromatase) inhibitor and a mutagen. It is a pyrroline and a pyridine alkaloid.
Molecule SMILES: c1cncc(C2=NCCC2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Myosmine is a natural product found in Euglena gracilis, Nicotiana tabacum, and Duboisia hopwoodii with data available.
Molecule SMILES: O=C1CC(O)CC2C3CC(CN12)C1CCCCN1C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Nuttalline is a natural product found in Chamaecytisus supinus, Cytisus multiflorus, and Lupinus sericeus with data available.
Molecule SMILES: CCC(C)C(=O)c1c(O)c(CC=C(C)CCC=C(C)C)c2oc(=O)cc(-c3ccccc3)c2c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 8-[(2E)-3,7-dimethylocta-2,6-dienyl]-5,7-dihydroxy-6-[(2R)-2-methylbutanoyl]-4-phenylchromen-2-one is a natural product found in Mesua ferrea with data available.
Molecule SMILES: CC1=CC(=O)OC1C(C)CC=CC1=C2C(=O)NC(Cc3ccccc3)C2C(C)C(C)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Asperchalasin E is a natural product found in Aspergillus with data available.
Molecule SMILES: CC(C)=CCc1cc(C2COc3cc(O)cc(O)c3C2=O)cc(O)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (3S)-3-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-one is a natural product found in Bolusanthus speciosus with data available.
Molecule SMILES: Cc1c[n+](CCc2ccc(O)cc2)cc2c1CCC2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: N-(p-Hydroxyphenethyl)actinidine is a primary amine.
Molecule SMILES: COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Trimetrexate is a parenterally administered folate antagonist that is used as a second line therapy for severe Pneumocystis jirovecii (previously carinii) pneumonia. Trimetrexate therapy has been associated with transient, mild serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury.
Molecule SMILES: COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Trimetrexate is a member of quinazolines. It has a role as an antifungal drug.
Molecule SMILES: COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Molecule SMILES: COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Trimetrexate is a methotrexate derivative with potential antineoplastic activity.  Trimetrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine nucleotides and thymidylate, with subsequent inhibition of DNA and RNA synthesis.  Trimetrexate also exhibits antiviral activity. (NCI04)