IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=C(CCC1(C)C(C)CCC2(C)C1CCC(O)C2(C)O)C(O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 5-(4,5-dihydroxy-3-methylidenepentyl)-1,5,6,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-2H-naphthalene-1,2-diol is a natural product found in Aglaia spectabilis with data available.
Molecule SMILES: Nc1c(NCC(O)C(O)C(O)CO)[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 5-amino-6-(D-ribitylamino)uracil is an aminouracil that is D-ribitol in which the hydroxy group at position 1 is substituted by the 6-amino group of 5,6-diaminouracil. Early intermediate in bacterial riboflavin synthesis. It has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a hydroxypyrimidine and an aminouracil. It is functionally related to a ribitol.
Molecule SMILES: Nc1c(NCC(O)C(O)C(O)CO)[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5-Amino-6-ribitylamino uracil is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: Nc1c(NCC(O)C(O)C(O)CO)[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 5-amino-6-(D-ribitylamino)uracil is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: Nc1c(NCC(O)C(O)C(O)CO)[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 5-Amino-6-(D-ribitylamino)uracil is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: Nc1c(NCC(O)C(O)C(O)CO)[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 5-amino-6-(D-ribitylamino)uracil is a natural product found in Russula sardonia, Russula paludosa, and other organisms with data available.
Molecule SMILES: C=C1C(O)C2CC(C)(CO)CC2=C(C)C12CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Coprinastatin 1 is a natural product found in Coprinopsis cinerea with data available.
Molecule SMILES: CN(C)C(=S)SC(=S)N(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Tetramethylthiuram monosulfide is a Standardized Chemical Allergen. The physiologic effect of tetramethylthiuram monosulfide is by means of Increased Histamine Release, and Cell-mediated Immunity.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 9,12,15-octadecatrienal is a fatty aldehyde.
Molecule SMILES: CNC1CCC2Nc3c(O)cc(C(N)=O)cc3C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Hydroxyl frovatriptan is a member of carbazoles.
Molecule SMILES: CC(C)=CCc1cccc2c3c([nH]c12)CNC(C(=O)O)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Penipaline A is a natural product found in Penicillium paneum with data available.
Molecule SMILES: C=C(CCC12OC(C(=O)O)C(O)(C(=O)O)C(C(=O)O)(O1)C(OC(=O)CC(O)C(C)CC(C)CC)C2O)C(O)C(C)Cc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 4,7-Dihydroxy-6-(3-hydroxy-4,6-dimethyloctanoyl)oxy-1-(4-hydroxy-5-methyl-3-methylidene-6-phenylhexyl)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid is a natural product found in Plagiostoma with data available.
Molecule SMILES: CC1=CCCC(C=O)=CC(OC(=O)c2cc3c(c4c2c([N+](=O)[O-])cc2ccccc24)OCO3)CC(C)=CCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Aristoloterpenate II is a natural product found in Aristolochia kaempferi and Aristolochia heterophylla with data available.
Molecule SMILES: CCC(C)C1=C2N=C3OC=CC=CC3(O)C(=O)N2C(Cc2ccccc2)C(=O)N1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Oxepinamide E is a natural product found in Aspergillus puniceus with data available.
Molecule SMILES: CC=C1CN2CCC3(O)c4ccccc4N4C(C(=O)OC)C1CC2C43

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: methyl (8S,13E,14S,16S,17R,18S)-13-ethylidene-8-hydroxy-1,11-diazapentacyclo[12.3.1.02,7.08,17.011,16]octadeca-2,4,6-triene-18-carboxylate is a natural product found in Alstonia angustifolia with data available.
Molecule SMILES: CCCC=C1OC(=O)C2=C1CCC1C3C=C4C(=O)OC(=CCCC)C4(CC3)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1S,2S,6E,10S,11S,16E)-6,16-di(butylidene)-5,15-dioxapentacyclo[9.5.2.01,13.02,10.03,7]octadeca-3(7),12-diene-4,14-dione is a natural product found in Ligusticum porteri with data available.
Molecule SMILES: CC(=O)NC1C(OC2C(C(=O)O)OC(OCC(O)CO)C(NC(C)=O)C2O)OC(C(=O)O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (2R,3S,4R,5S,6R)-5-acetamido-6-[(2R,3S,4R,5S,6R)-5-acetamido-2-carboxy-6-[(2S)-2,3-dihydroxypropoxy]-4-hydroxyoxan-3-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid is a natural product found in Halomonas with data available.
Molecule SMILES: CC(C)CCCCCCC(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2,9-dimethyldecane is an alkane that is decane which is substituted by a methyl group at positions 2 and 9. It has a role as a bacterial metabolite, a plant metabolite, a volatile oil component and a fungal metabolite. It is an alkane and a volatile organic compound.
Molecule SMILES: CC1CCC2C(C)C3CC2(C1=O)C(=O)C1(C)C(=O)OC(C)(C)C31

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Elisabanolide is a natural product found in Antillogorgia elisabethae with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(COC2OC(C)C(O)C(O)C2O)C(OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4OC4OC(CO)C(OC5OC(COC6OC(C)C(O)C(O)C6O)C(O)C(O)C5O)C(O)C4NC(C)=O)C(O)C(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(OC5OC(COC6(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O6)C(O)C(O)C5O)C(O)C4NC(C)=O)C3O)C(O)C2NC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (2R,4S,5R,6R)-5-Acetamido-2-[[(2R,3R,4S,5R,6S)-6-[(2R,3S,4R,5R,6S)-5-acetamido-6-[(2R,3S,4S,5S,6R)-2-[(2S,3S,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-5-acetamido-6-[(2R,3S,4R,5R)-5-acetamido-4,6-dihydroxy-2-[[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-[[(2S,3S,4S,5S,6R)-3-[(2S,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,5-dihydroxyoxan-4-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of carbohydrates and carbohydrate derivatives.
Molecule SMILES: CC=C1CN2CCC34c5ccccc5N5C6OC(C(C1CC23)C54)N1c2ccccc2C23CCN4CC(=CO)C(CC42)C6C13

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (E)-[(1R,9R,10S,11R,13S,17R,25R,26S,27R,33S,35S,37S,39Z)-39-ethylidene-36-oxa-8,14,24,30-tetrazadodecacyclo[25.5.2.211,14.11,26.19,25.110,17.02,7.013,17.018,23.030,33.08,35.024,37]nonatriaconta-2,4,6,18,20,22-hexaen-28-ylidene]methanol is a natural product found in Strychnos matopensis with data available.
Molecule SMILES: COc1ccc(C2Oc3cc(O)c(OC)c(O)c3C(=O)C2O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 3,5,7-Trihydroxy-4',6-dimethoxyflavanone is a member of flavonoids and an ether.
Molecule SMILES: C=C1CC23CC1CCC2C1(C)CCC(O)C2(C)C(=O)OC(C3O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (1S,2S,5R,8R,9R,10R,13S,14S,17S)-9,14-dihydroxy-1,13-dimethyl-6-methylidene-11-oxapentacyclo[8.6.1.15,8.02,8.013,17]octadecan-12-one is a natural product found in Fusarium fujikuroi with data available.
Molecule SMILES: COC1C=CC2=CCN3CC(O)c4cc5c(cc4C23C1)OCO5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 19-Methoxy-5,7-dioxa-13-azapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,15,17-pentaen-11-ol is a natural product found in Erythrina suberosa with data available.
Molecule SMILES: O=C(O)CCCCCc1cc(=O)c2ccccc2[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 6-(4-oxo-1H-quinolin-2-yl)hexanoic acid is a natural product found in Haplophyllum cappadocicum with data available.
Molecule SMILES: CN(C)C(=O)c1cccc(-c2ccc(C3C(CO)N4CCCCN(CC5CCOCC5)CC34)cc2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 3-[4-[(8R,9R,10S)-10-(hydroxymethyl)-6-(4-oxanylmethyl)-1,6-diazabicyclo[6.2.0]decan-9-yl]phenyl]-N,N-dimethylbenzamide is a member of biphenyls.
Molecule SMILES: COC1CC(OC2CCC3(C=O)C4CCC5(C)C(C6=CC(=O)OC6)CCC5(O)C4CCC3(O)C2)OC(C)C1OC1OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (3S,5S,8R,9S,10S,13R,14S,17R)-3-[(2R,4S,5S,6S)-5-[(2S,3R,4R,5R,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde is a natural product found in Crossosoma bigelovii with data available.
Molecule SMILES: CCS(=O)(=O)Nc1ccc2c(c1)C(=O)N(C)CC(OC)C(C)CN(CCC(F)(F)F)C(C)CO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-[(4S,7R,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-(3,3,3-trifluoropropyl)-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]ethanesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CCCCOC(=O)C=Cc1ccc(OC(=O)C(C)C)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [4-(3-Butoxy-3-oxoprop-1-enyl)-2-hydroxyphenyl] 2-methylpropanoate is a natural product found in Traversia baccharoides with data available.
Molecule SMILES: CNCC1OCCCCC(C)Oc2ccc(NC(=O)Nc3ccccc3)cc2C(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 1-[(3S,9S,10S)-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-9-(methylaminomethyl)-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]-3-phenylurea is an azamacrocycle and a lactam.
Molecule SMILES: CC=CC=CC#CC=CC=CCCCCC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 6,8,12,14-Hexadecatetrene-10-ynal is a natural product found in Centaurea cineraria, Centaurea dealbata, and Centaurea montana with data available.
Molecule SMILES: OCc1ccc2oc(-c3ccc(O)cc3)nc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Nocarbenzoxazole F is a natural product found in Nocardiopsis lucentensis with data available.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCc1cc(OC(C)=O)cc(OC(C)=O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (3-Acetyloxy-5-heptadeca-8,11,14-trienylphenyl) acetate is a natural product found in Stylogyne turbacensis with data available.
Molecule SMILES: CC(=CC=CC=CC=CC=CCCC=CC(C)C(O)C(C)C(O)C=CC=CC=CC=CC=CCC(O)C(C)C(=O)CC(O)CC(O)CC(O)C=CCC(O)CC(O)CC(O)CC(O)C=CCC(O)C=CCC(O)CC(O)CCCN)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Linearmycin B is a natural product found in Streptomyces with data available.
Molecule SMILES: CC=Cc1cc(C)c(O)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 6-methylisoeugenol is an isoeugenol derivative carrying a 6-methyl substituent. It is functionally related to an isoeugenol.
Molecule SMILES: CC=Cc1cc(C)c(O)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 6-Methylisoeugenol is a natural product found in Daucus carota and Acorus calamus with data available.
Molecule SMILES: COc1cc(O)c2ccc(=O)oc2c1CC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Sibiricol is a natural product found in Murraya exotica and Murraya paniculata with data available.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-palmitoyl-2-[(9Z,12Z,15Z)-octadecatrienoyl]-sn-glycero-3-phosphocholine is a phosphatidylcholine 34:3 in which the acyl groups specified at positions 1 and 2 are palmitoyl and (9Z,12Z,15Z)-octadecatrienoyl (alpha-linolenoyl) respectively. It has a role as a mouse metabolite. It is functionally related to an alpha-linolenic acid and a hexadecanoic acid.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: PC(16:0/18:3(9Z,12Z,15Z)) is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)([O-])OCC[N+](C)(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: PC(16:0/18:3(9Z,12Z,15Z)) is a natural product found in Trypanosoma brucei with data available.
Molecule SMILES: COc1ccc(C(=O)Nc2ccc3c(c2)C(=O)N(C)C2CCC(CC(=O)NCC4CC4)OC2CO3)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: N-[(2S,4aS,12aS)-2-[2-(cyclopropylmethylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-4-methoxybenzamide is a member of benzamides.
Molecule SMILES: CCCC1NC(=O)C(C)N(C)C(=O)C(C)(C)C(=O)C(C)NC(=O)C(Cc2ccccc2)N(C)C(=O)C(C(C)C)N(C)C(=O)CNC(=O)C(CC(C)C)N(C)C(=O)CNC(=O)C(C(C)CC)OC(=O)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Ibu-epidemethoxylyngbyastatin 3 is a cyclodepsipeptide. It has a role as a metabolite.
Molecule SMILES: CCCC1NC(=O)C(C)N(C)C(=O)C(C)(C)C(=O)C(C)NC(=O)C(Cc2ccccc2)N(C)C(=O)C(C(C)C)N(C)C(=O)CNC(=O)C(CC(C)C)N(C)C(=O)CNC(=O)C(C(C)CC)OC(=O)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Ibu-Epidemethoxylyngbyastatin 3 is a natural product found in Leptolyngbya with data available.
Molecule SMILES: CC1NC(=O)C2CCCN2C(=O)C(CC(N)=O)NC(=O)C2CSSCC(N)C(=O)NC3CSSCC(NC1=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)O)CSSCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(=O)O)NC3=O)C(=O)N2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Linaclotide is a fourteen-membered heterodetic cyclic peptide consisting of Cys, Cys, Glu, Tyr, Cys, Cys, Asn, Pro, Ala, Cys, Thr, Gly, Cys and Tyr residues joined in sequence and cyclised by three disulfide bonds: between Cys(1) and Cys(6), between Cys(2) and Cys(10), and between Cys(5) and Cys(13). Used for treatment of irritable bowel syndrome accompanied by constipation. It has a role as a guanylate cyclase 2C agonist.
Molecule SMILES: CC1NC(=O)C2CCCN2C(=O)C(CC(N)=O)NC(=O)C2CSSCC(N)C(=O)NC3CSSCC(NC1=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)O)CSSCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(=O)O)NC3=O)C(=O)N2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Linaclotide is an orally administered, peptide agonist of guanylate cyclase 2C for the treatment of irritable bowel syndrome. Chemically, it is a heterodetic cyclic peptide and consists of fourteen amino acids. The protein sequence is as follows: Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr. There are three disulfide bonds which are located between Cys1 and Cys6; between Cys2 and Cys10; and between Cys5 and Cys13. FDA approved on August 30, 2012.
Molecule SMILES: CC1NC(=O)C2CCCN2C(=O)C(CC(N)=O)NC(=O)C2CSSCC(N)C(=O)NC3CSSCC(NC1=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)O)CSSCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(=O)O)NC3=O)C(=O)N2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities.  Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.
Molecule SMILES: CCC=CCC=CCC=CCC1OC1CC=CCC=CCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoic acid is an EpDPE obtained by formal epoxidation across the 10,11-double bond of all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. It has a role as a human xenobiotic metabolite. It is functionally related to an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid. It is a conjugate acid of a (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosapentaenoate.
Molecule SMILES: CC(=CCCC(C)=CCC1(O)C(=O)c2c(O)cc(C)c3c(O)c(C)c(O)c(c23)C1=O)CCC=C(CCC(O)C(C)(C)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Asperphenalenone C is a natural product found in Aspergillus with data available.
Molecule SMILES: Nc1nccc(CC([NH3+])C(=O)[O-])n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Lathyrine is a natural product found in Euglena gracilis and Lathyrus tingitanus with data available.
Molecule SMILES: CC=C1C(=O)OC23C=CC4C(C(=O)OC)=COC(OC12)C43

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: methyl (1S,4S,8S,10S,11E,14S)-11-ethylidene-12-oxo-7,9,13-trioxatetracyclo[6.5.1.01,10.04,14]tetradeca-2,5-diene-5-carboxylate is a natural product found in Allamanda cathartica with data available.