IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(=CC(=O)CC(C)C)C1CC=C(C(=O)O)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (4R)-4-[(Z)-6-methyl-4-oxohept-2-en-2-yl]cyclohexene-1-carboxylic acid is a natural product found in Cedrus libani with data available.
Molecule SMILES: CC(=O)OC1CC2C(O)C=C3CC(C)(C(=O)C(OC(C)=O)C(=C1C)C2(C)C)C(OC(C)=O)CC3OC(=O)CC(c1ccccc1)N(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2alpha-Hydroxy-5alpha-[[(R)-3-(dimethylamino)-3-phenylpropionyl]oxy]-7beta,10beta,13alpha-triacetoxy-2,3-seco-2,20-cyclotaxa-4(20),11-diene-9-one is a natural product found in Taxus canadensis with data available.
Molecule SMILES: C#CCCCC(=CC(=O)N(C)C(C(=O)N(C)C(C(=O)N(C)C(C(=O)N(C)C(C(N)=O)C(C)C)C(C)C)C(C)C)C(C)C)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methoxy-N-methyloct-2-en-7-ynamide is a natural product found in Lyngbya polychroa and Lyngbya sordida with data available.
Molecule SMILES: CC(=O)OCc1ccc(C2(COC(=O)C=Cc3ccccc3)CO2)c(OC(=O)C(C)C)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: [5-(acetyloxymethyl)-2-[(2S)-2-[[(E)-3-phenylprop-2-enoyl]oxymethyl]oxiran-2-yl]phenyl] 2-methylpropanoate is a natural product found in Ageratina areolaris and Ageratina palmeri with data available.
Molecule SMILES: CCC(C)CC(C)CC(C)C=C(C)C1OC(O)(C(C)(O)C(=O)NC2C(=O)N3NCCCC3C(=O)N(O)CC(=O)N(C)CC(=O)NCC(=O)N(C)CC(=O)OC2C(C)C)CCC1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2R)-2-hydroxy-N-[(3S,4S,19R)-17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl]-2-[(5S,6R)-2-hydroxy-5-methoxy-6-[(E,4S,6S,8R)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide is a natural product found in Actinomadura verrucosospora with data available.
Molecule SMILES: N#CC1C(c2ccccc2)C(CO)N1C(=O)Nc1cccc(F)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2R,3S,4S)-2-cyano-N-(3-fluorophenyl)-4-(hydroxymethyl)-3-phenylazetidine-1-carboxamide is a member of azetidines, a ring assembly and a member of benzenes.
Molecule SMILES: COc1cc(CO)cc2c1[nH]c1ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Koenoline is a member of carbazoles.
Molecule SMILES: COc1cc(CO)cc2c1[nH]c1ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1-methoxy-9H-carbazol-3-yl)methanol is a natural product found in Murraya euchrestifolia and Murraya koenigii with data available.
Molecule SMILES: COc1c(C(O)CC=C(C)C)cc(O)c2c1C(=O)C=CC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 8-Hydroxy-6-(1-hydroxy-4-methylpent-3-enyl)-5-methoxynaphthalene-1,4-dione is a natural product found in Onosma hispida with data available.
Molecule SMILES: COc1cc(O)ccc1-c1cc2cc3c(cc2o1)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 4-Furo[2,3-f][1,3]benzodioxol-6-yl-3-methoxyphenol is a natural product found in Cissus discolor with data available.
Molecule SMILES: CC1CCCC=CCC=CCCCC(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: R-cucujolide V is a macrolide.
Molecule SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Bisoprolol is a cardioselective beta-blocker used in the treatment of hypertension. Bisoprolol has not been linked to instances of clinically apparent drug induced liver injury.
Molecule SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Bisoprolol is a secondary alcohol and a secondary amine. It has a role as an antihypertensive agent, a beta-adrenergic antagonist, an anti-arrhythmia drug and a sympatholytic agent.
Molecule SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure. It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and [Labetalol]. It may be used alone or in combination with other drugs to manage hypertension and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.
Molecule SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Bisoprolol is a beta-Adrenergic Blocker. The mechanism of action of bisoprolol is as an Adrenergic beta-Antagonist.
Molecule SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Bisoprolol is a selective beta-1 adrenergic receptor antagonist with antihypertensive activity and devoid of intrinsic sympathomimetic activity. Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevent the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.
Molecule SMILES: CC1C(=O)NC(O)(Cc2ccccc2)c2nc3c(O)cccc3c(=O)n21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Puniceloid B is a natural product found in Aspergillus puniceus with data available.
Molecule SMILES: CC=CC1COC2(C)NC(=O)NCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Astronyurea is a natural product found in Astrosphaeriella nypae with data available.
Molecule SMILES: CC(=O)OC1CC2C(OC(C)=O)C3C4(CO4)C(OC(C)=O)CC(OC(C)=O)C3(C)C(OC(C)=O)C(OC(C)=O)C(=C1C)C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Baccatin I is a natural product found in Taxus cuspidata with data available.
Molecule SMILES: CC1CCC2(C(=O)O)CCC3(C(=O)O)C(=CCC4C5(C)CCC(OC6OCC(O)C(O)C6OS(=O)(=O)O)C(C)(C)C5CCC43C)C2C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Zygophyloside O is a natural product found in Zygophyllum fabago and Tetraena coccinea with data available.
Molecule SMILES: COc1cc(O)cc2cc3c(c(O)c12)C(=O)CC(C)C3O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Isoasperflavin is a natural product found in Aspergillus glaucus with data available.
Molecule SMILES: CC1(C)CC(O)CC2(C)C1CCC13CC(CCC12)C(O)(CO)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Siegesbeckiol is a natural product found in Pteris multifida, Isodon flavidus, and Sigesbeckia pubescens with data available.
Molecule SMILES: COc1cc2c(cc1O)CN1CCC23C=CC(O)CC13

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Siculine is a natural product found in Crinum asiaticum, Sternbergia sicula, and Sternbergia lutea with data available.
Molecule SMILES: CCCCCC(O)CCC1C(O)CC(O)C1CC=CCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 13,14-Dihydro PGF2alpha is a prostanoid.
Molecule SMILES: CC(C)(O)C1Cc2ccc(CC3=C(c4ccc(O)cc4)C(=O)NC3=O)cc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 3-(4-hydroxyphenyl)-4-[[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-6-yl]methyl]pyrrole-2,5-dione is a natural product found in Aspergillus terreus with data available.
Molecule SMILES: COc1cc(O)cc2c1C(=O)c1c(cc(C)c(C(=O)OCC(O)CO)c1O)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (+)-Variecolorquinone A is a natural product found in Aspergillus glaucus with data available.
Molecule SMILES: CC1CCCCOC(CN(C)C(=O)NC2CCCCC2)C(C)CN(C(C)CO)C(=O)c2cc(NC(=O)CCC(F)(F)F)ccc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-[(3R,9S,10S)-9-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]-4,4,4-trifluorobutanamide is an azamacrocycle and a lactam.
Molecule SMILES: CC1=CC2C(=C(C)CCC3(C)C(=O)C=C(C(C)C)C3CC1)OC(=O)C2C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Atranone E is a natural product found in Stachybotrys chartarum with data available.
Molecule SMILES: COC(=O)CCC(=O)OCC12CCC(C)C(C)(CCC(C)=CCOC(=O)CCC(=O)OCC34CCC(C)C(C)(CCC(C)=CCOC(C)=O)C3CCC=C4C)C1CCC=C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 4-O-[[(4aS,7R,8S,8aR)-8-[(E)-5-[4-[[(4aS,7R,8S,8aR)-8-[(E)-5-acetyloxy-3-methylpent-3-enyl]-4,7,8-trimethyl-1,2,5,6,7,8a-hexahydronaphthalen-4a-yl]methoxy]-4-oxobutanoyl]oxy-3-methylpent-3-enyl]-4,7,8-trimethyl-1,2,5,6,7,8a-hexahydronaphthalen-4a-yl]methyl] 1-O-methyl butanedioate is a natural product found in Chrysothamnus stylosus with data available.
Molecule SMILES: CC(C)C1NC(=O)c2csc(n2)C(C(C)C)NC(=O)C2N=C(OC2C)C(C(C)C)NC(=O)c2csc(n2)C(Cc2ccccc2)NC(=O)C2COC1=N2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Patellamide F is a natural product found in Lissoclinum patella with data available.
Molecule SMILES: CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(C[N+]3(C)CCCC3)CSC12)c1csc(N)n1.Cl.O.[Cl-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Cefepime Hydrochloride is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefepime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins.
Molecule SMILES: COc1ccc2cc1Oc1ccc(cc1)CC1c3c(c(O)c(OC)c4c3Oc3cc5c(cc3O4)CCN=C5C2)CCN1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1',2'-Didehydro-O12'-methylkohatine is a natural product found in Cocculus pendulus with data available.
Molecule SMILES: C=C(C)C(O)CCC(O)(COC1OC(CO)C(O)C(O)C1O)C1CCC2(C)C1CCC1C3(C=O)CCC(OC4OCC(O)C(OC5OCC(O)C(O)C5O)C4OC4OC(C)C(O)C(O)C4O)C(C)(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (3S,5S,8R,9S,10S,13R,14R,17S)-17-[(2S,5S)-2,5-dihydroxy-6-methyl-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-6-en-2-yl]-3-[(2S,3R,4S,5S)-5-hydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-4,4,8,14-tetramethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde is a natural product found in Gynostemma pentaphyllum with data available.
Molecule SMILES: CC(=O)NC1CC2C(C)(C)OC3CC(=O)OC32CC23CCC4(C)C(=O)C(C)(O)C5C6OC(=O)C(C)(O)C6OC(O2)(C(O)=C13)C54

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N-[(1S,3R,7R,10S,12S,15S,17S,18R,21R,22S,23R,25S,29S)-14,18,23-trihydroxy-9,9,18,23,25-pentamethyl-5,19,24-trioxo-4,8,16,20,28-pentaoxaoctacyclo[13.12.1.115,22.01,13.03,7.03,10.017,21.025,29]nonacos-13-en-12-yl]acetamide is a natural product found in Schisandra sphenanthera with data available.
Molecule SMILES: O=C1CC2C(O)C=C(CO)C2CO1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (4aR,5S,7aS)-5-hydroxy-7-(hydroxymethyl)-4,4a,5,7a-tetrahydro-1H-cyclopenta[c]pyran-3-one is a natural product found in Pedicularis chinensis and Scrophularia buergeriana with data available.
Molecule SMILES: CC(NC(=O)CC1C=CC(NC(=O)Nc2ccc3c(c2)OCO3)C(CO)O1)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2-[(2R,3R,6S)-3-[[(1,3-benzodioxol-5-ylamino)-oxomethyl]amino]-2-(hydroxymethyl)-3,6-dihydro-2H-pyran-6-yl]-N-[(1R)-1-phenylethyl]acetamide is a member of benzodioxoles.
Molecule SMILES: O=S(=O)([O-])c1ccc(N=Nc2ccc(O)c3ccccc23)cc1.[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: CI Acid Orange 20 is an organic molecular entity.
Molecule SMILES: CC(C)CCCCC(=O)C1C(=O)OCC1COP(=O)([O-])[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate(2-) is a [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate(2-) obtained by deprotonation of the phosphate OH groups of [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl dihydrogen phosphate; major species at pH 7.3. It is a conjugate base of a [(3S)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate.
Molecule SMILES: CC(C)=CC1CC(C)C2CCC(C)C3=C2C(O)(OC3=O)C1(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Sandresolide C is a natural product found in Antillogorgia elisabethae with data available.
Molecule SMILES: CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CC(O)C3(C)C1C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (25R)-3beta-[(2-O-alpha-L-Rhamnopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-galactopyranosyl)oxy]spirosta-5-ene-12beta-ol is a natural product found in Solanum lycocarpum with data available.
Molecule SMILES: COC1=CC(=O)c2ccc3cc(OC)c(OC)cc3c2C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Sphenone A is a natural product found in Odontosoria biflora with data available.
Molecule SMILES: Cc1ccc(C=C2SC(=S)N(CCCC(=O)Nc3ccccn3)C2=O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 4-[5-[(4-methylphenyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]-N-(2-pyridinyl)butanamide is an aromatic amide.
Molecule SMILES: CC(=O)OCC1(C)CCCC2(C)C1CCC13CC(=O)C(CC(OC(C)=O)C12)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (11-Acetyloxy-5,9-dimethyl-14-oxo-5-tetracyclo[11.2.1.01,10.04,9]hexadecanyl)methyl acetate is a natural product found in Croton kongensis with data available.
Molecule SMILES: O=c1[nH]c(=O)n(C2CCCO2)cc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Tegafur is an organohalogen compound and a member of pyrimidines.
Molecule SMILES: O=c1[nH]c(=O)n(C2CCCO2)cc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with [DB09257] and [DB03209], or along with [DB00544] as [DB09327]. Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU by blocking the enzyme responsible for its degradation, or serves to limit the toxicity of 5-FU by ensuring high concentrations of 5-FU at a lower dose of tegafur. When converted and bioactivated to 5-FU, the drug mediates an anticancer activity by inhibiting thymidylate synthase (TS) during the pyrimidine pathway involved in DNA synthesis. 5-FU is listed on the World Health Organization's List of Essential Medicines.
Molecule SMILES: O=c1[nH]c(=O)n(C2CCCO2)cc1F

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Tegafur is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil in the liver by the cytochrome P-450 enzyme. Subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells.  FdUMP inhibits DNA synthesis and cell division by inhibiting thymidylate synthase and reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate. (NCI04)
Molecule SMILES: CCc1ccc(-n2nnnc2SCC(=O)Nc2ccc(NC(C)=O)cc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: N-(4-acetamidophenyl)-2-[[1-(4-ethylphenyl)-5-tetrazolyl]thio]acetamide is a member of tetrazoles.
Molecule SMILES: CC12CCC3(C)C(=CC(=O)C4C5(C)CCC(O)C(C)(C)C5CCC43C)C1CC(C)(C(=O)O)C(O)C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Glabric acid is a triterpenoid.
Molecule SMILES: CNC1C(O)CC(OC2CC=C(C)CC(C)(O)C(C)C=CCCC(C)CNC(=O)C=CC=CC2C)OC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Sannastatin is a natural product found in Streptomyces sannanensis with data available.
Molecule SMILES: COC1C=C(C)CC(OC(C)=O)C2(O)C(CC2(C)C)C(CO)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(1S,2S,6S,9R)-1-hydroxy-8-(hydroxymethyl)-6-methoxy-4,11,11-trimethyl-2-bicyclo[7.2.0]undec-4-enyl] acetate is a natural product found in Pestalotiopsis with data available.