IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC(C)CCCCCCCCCCCN(C)OP(=O)(O)N(CC(N)=O)P(=O)(O)OC1CC(O)C(CO)=C1OCC1OC(N2CCC(=N)NC2=O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-(2-amino-2-oxoethyl)-[2-[[3,4-dihydroxy-5-(4-imino-2-oxo-1,3-diazinan-1-yl)oxolan-2-yl]methoxy]-4-hydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]oxy-N-[hydroxy-[methyl(12-methyltridecyl)amino]oxyphosphoryl]phosphonamidic acid is a natural product found in Streptomyces with data available.
Molecule SMILES: CCC1C=CC(C(C)O)OC(=O)C2(C)C=CC(=O)NC3=C2C(=O)c2c(cc(C)c(O)c2C(=O)CC1)C3=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Hygrocin G is a natural product found in Streptomyces with data available.
Molecule SMILES: COC(=O)C=Cc1cc(OC)c(OC)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-, methyl ester, cis is a natural product found in Piper arborescens, Piper caninum, and other organisms with data available.
Molecule SMILES: CN1CCCCC1C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Methylpipecolic acid is an alpha-amino acid.
Molecule SMILES: COC(=O)c1ccc2c(c1)CCC(C)(C)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Methyl 2,2-dimethyl-6-chromanecarboxylate is a natural product found in Piper aduncum with data available.
Molecule SMILES: OCC=CC=CC1Cc2cc(O)cc(O)c2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2R)-2-[(1E,3E)-5-hydroxypenta-1,3-dienyl]-2,3-dihydro-1-benzofuran-5,7-diol is an aliphatic alcohol.
Molecule SMILES: Nc1ccc(N)c2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1,4-naphthalenediamine is a dark green to black crystalline solid. (NTP, 1992)
Molecule SMILES: COC1CCC2CCN(C)C(=O)C(C)N(C)C(=O)c3cccc(C#N)c3OCC1O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: LSM-39017 is a lactam and an azamacrocycle.
Molecule SMILES: COC1C(O)CC2C3CC=C4CC(O)CCC4(C)C3CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 17beta-Methoxyandrost-5-ene-3beta,16beta-diol is a 3-hydroxy steroid. It has a role as an androgen.
Molecule SMILES: NC(N)=[NH+]CCC(O)C([NH3+])C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (3S)-3-hydroxy-L-arginine(1+) is an alpha-amino-acid cation obtained by deprotonation of the carboxy group and protonation of the amino and guanidino groups of (3S)-3-hydroxy-L-arginine It is a conjugate acid of a (3S)-3-hydroxy-L-arginine.
Molecule SMILES: OCC1OC(c2nc3ccccc3[nH]2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2-(beta-D-glucosyl)benzimidazole is a C-glycosyl compound and a member of benzimidazoles.
Molecule SMILES: COc1ccc(CC(C)C(C)Cc2ccc(OC)c(OC)c2)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
Molecule SMILES: COc1ccc(CC(C)C(C)Cc2ccc(OC)c(OC)c2)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Terameprocol is a synthetic tetra-methylated derivative of nordihydroguaiaretic acid (NDGA) and transcriptional inhibitor with potential antiviral, antiangiogenic, and antineoplastic activities. Terameprocol competes with the transcription factor Sp1 for specific Sp1 DNA binding domains within gene promoter regions during DNA synthesis. In virally-infected cells, blocking of the Sp1 binding site suppresses Sp1-regulated viral promoter activity and gene expression, thereby inhibiting viral transcription and replication. In tumor cells, blockage of Sp1 binding sites by this agent interferes with the transcription of the Sp1-dependant genes cyclin-dependant kinase (Cdc2), survivin, and vascular endothelial growth factor (VEGF), which are overexpressed in a variety of cancers. By suppressing Sp1-regulated transcription of these genes, terameprocol may reduce tumor angiogenesis and tumor cell proliferation and induce tumor cell apoptosis.
Molecule SMILES: COc1ccc(CC(C)C(C)Cc2ccc(OC)c(OC)c2)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Terameprocol is a natural product found in Schisandra propinqua, Schisandra rubriflora, and Otoba novogranatensis with data available.
Molecule SMILES: COC(=O)Nc1nc2ccccc2n1C(=O)NCCCCCC#N

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Cypendazole is a benzimidazole fungicide and a benzimidazolylcarbamate fungicide.
Molecule SMILES: COC(=O)Nc1nc2ccccc2n1C(=O)NCCCCCC#N

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Cypendazole is a carbamate pesticide. Carbamate pesticides are derived from carbamic acid and kill insects in a similar fashion as organophosphate insecticides. They are widely used in homes, gardens and agriculture. The first carbamate, carbaryl, was introduced in 1956 and more of it has been used throughout the world than all other carbamates combined. Because of carbaryl's relatively low mammalian oral and dermal toxicity and broad control spectrum, it has had wide use in lawn and garden settings. Most of the carbamates are extremely toxic to Hymenoptera, and precautions must be taken to avoid exposure to foraging bees or parasitic wasps. Some of the carbamates are translocated within plants, making them an effective systemic treatment. (L795)
Molecule SMILES: C=C1C(O)CCC2C1CCC1CC(C)(C3CO3)CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3beta-hydroxy-15,16-epoxydolabrene is a tricyclic diterpenoid that is 15,16-epoxydolabrene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is a secondary allylic alcohol, an epoxide and a tricyclic diterpenoid. It is functionally related to a 15,16-epoxydolabrene.
Molecule SMILES: CC1CCCCN1c1ncnc(N)c1[N+](=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 6-(2-methyl-1-piperidinyl)-5-nitro-4-pyrimidinamine is a C-nitro compound.
Molecule SMILES: CC1N=CC23CCC4C(CC=C5CC(NC=O)CCC54C)C2CCC13

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,13-dimethyl-7-azapentacyclo[10.8.0.02,9.05,9.013,18]icosa-7,18-dien-16-yl]formamide is a natural product found in Holarrhena curtisii with data available.
Molecule SMILES: CCC(=O)OC(OP(=O)(CCCCc1ccccc1)CC(=O)N1CC(C2CCCCC2)CC1C(=O)[O-])C(C)C.[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Fosinopril Sodium is the sodium salt of fosinopril, a phosphinic acid-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Fosinopril sodium is an ester prodrug that is hydrolysed by esterases to its active metabolite fosinoprilat. Fosinoprilat specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of the potent vasoconstrictor angiotensin II, resulting in diminished vasopressor activity. In addition, angiotensin II-mediated aldosterone secretion by adrenal cortex is decreased, which results in a decrease of sodium retention and an increase of serum potassium. (NCI05)
Molecule SMILES: Oc1ccc(C=Cc2cc(O)c(-c3c(O)cc(C=Cc4ccc(O)cc4)c4c(-c5cc(O)cc(O)c5)c(-c5ccc(O)cc5)oc34)c3oc(-c4ccc(O)cc4)c(-c4cc(O)cc(O)c4)c23)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Amurensin M is a natural product found in Vitis amurensis with data available.
Molecule SMILES: CC[NH+](CC)CC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Triethylammonium ion is an organoammonium cation having three ethyl substituents on the nitrogen atom.
Molecule SMILES: COC(=O)C1(C)CCC2(C(=O)OC3OC(CO)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6O)C(C)(C)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-O-methyl 4a-O-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (2R,4aS,6aS,6aS,6bR,8aR,10S,12aR,14bR)-10-[(2S,3S,4R,5S,6S)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2,6a,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-2,4a-dicarboxylate is a natural product found in Phytolacca icosandra with data available.
Molecule SMILES: CC(=O)OCC1=CCC2(C)CCC(O)(C(C)C)C2CC(OC(C)=O)C(C)=CCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(1R,3aR,5Z,9E,11R,12aR)-11-acetyloxy-1-hydroxy-3a,10-dimethyl-1-propan-2-yl-2,3,4,7,8,11,12,12a-octahydrocyclopenta[11]annulen-6-yl]methyl acetate is a natural product found in Dictyota pardalis with data available.
Molecule SMILES: NC(N)=[NH+]CCCC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 4-guanidiniumylbutanal is conjugate acid of 4-guanidinobutanal; major species at pH 7.3. It is a conjugate acid of a 4-guanidinobutanal.
Molecule SMILES: Cc1noc(C)c1NC(=O)N(C)CC1OCCCCC(C)Oc2ccc(N(C)C)cc2C(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 1-[[(3R,9R,10R)-16-(dimethylamino)-12-[(2R)-1-hydroxypropan-2-yl]-3,10-dimethyl-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-9-yl]methyl]-3-(3,5-dimethyl-4-isoxazolyl)-1-methylurea is an azamacrocycle and a lactam.
Molecule SMILES: FC(Cl)=C(F)Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Dichlorodifluoroethylene is a liquid material, which may cause illness from inhalation. When heated to high temperatures it may decompose and emit toxic fumes. When in contact with water or steam it may produce additional fumes that can cause illness from inhalation. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Since it is a liquid it can easily penetrate the soil and contaminate groundwater and nearby streams.
Molecule SMILES: CSCCCCC(C(=O)O)C(O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 3-(4'-Methylthio)butylmalic acid is a dicarboxylic acid.
Molecule SMILES: COC(CC1OC(=O)CC(OC(N)=O)CC(C)CC(O)C(C)C(O)c2coc(n2)-c2coc(n2)-c2coc(n2)C=CCC(O)C1C)C(C)CCC(=O)C(C)C(OC)C(C)C=CN(C)C=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 9-O-Desmethylkabiramide B is a natural product found in Hexabranchus sanguineus with data available.
Molecule SMILES: CC(C)=CCCC1(C)C=Cc2cc(C(=O)C=Cc3ccc(O)cc3)c(O)cc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Isolespeol is a natural product found in Artocarpus altilis with data available.
Molecule SMILES: CC=C(C)C(=O)OC(COc1c2ccoc2c(OC)c2oc(=O)ccc12)C(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (S,Z)-3-Hydroxy-1-((9-methoxy-7-oxo-7H-furo[3,2-g]chromen-4-yl)oxy)-3-methylbutan-2-yl 2-methylbut-2-enoate is a natural product found in Peucedanum palustre, Peucedanum officinale, and other organisms with data available.
Molecule SMILES: CC(=O)OC1CC2C3CC4OC45C4OC4CC(=O)C5C3CC(O)C2(C)C1C(C)(O)C1CC(C)=C(C)C(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [(1S,2R,5S,7S,8S,10R,12R,13S,15S,16R,17S,18R)-16-[(1R)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-18-hydroxy-17-methyl-3-oxo-6,9-dioxahexacyclo[10.7.0.02,8.05,7.08,10.013,17]nonadecan-15-yl] acetate is a natural product found in Acnistus arborescens with data available.
Molecule SMILES: O=C1C(C2CC34c5ccccc5N5C(=O)CC6OCC=C7CN2C3CC7C6C54)=CC2C3CC4N(CCC45c4ccccc4N1C25)CC3=CCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (4aR,5aS,7R,8aR,13aS,15aS,15bR)-7-[(1R,12R,13R,14E,19S,21S)-14-(2-hydroxyethylidene)-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10-tetraen-10-yl]-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one is a natural product found in Strychnos icaja with data available.
Molecule SMILES: C=C1C(=O)C23C(O)C1CCC2C1OC(O)(C2C1CCCC2(C)C)C3O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 9,10,18-Trihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[8.6.1.15,8.02,8.011,16]octadecan-7-one is a natural product found in Isodon rubescens with data available.
Molecule SMILES: CC1(C)C=Cc2cc3c(cc2O1)OCC1(O)c2ccc(O)cc2OC31

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (-)-glyceollin II is a benzofuropyranochromene that is 3H,7H-[1]benzofuro[3,2-c]pyrano[3,2-g]chromene substituted at positions 7a and 10 by hydroxy groups and at position 3 by a gem-dimethyl group. It has a role as a phytoalexin.
Molecule SMILES: CC1(C)C=Cc2cc3c(cc2O1)OCC1(O)c2ccc(O)cc2OC31

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: glyceollin II is a natural product found in Glycine max, Glycine soja, and other organisms with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)Cc2cc(NS(C)(=O)=O)ccc2OC1CN(C)Cc1ccc(-c2ccccc2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N-[(2S,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenylphenyl)methyl]amino]methyl]-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]methanesulfonamide is a member of biphenyls.
Molecule SMILES: CC(C)=CCc1ccc(O)c(C2c3c(O)cc(C(=O)O)cc3C(=O)N2CCO)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Irpexine is a natural product found in Irpex lacteus with data available.
Molecule SMILES: CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Cheiroside A is a natural product found in Erysimum cheiri with data available.
Molecule SMILES: Cn1cc(-c2ccc(S(=O)(=O)n3ccc(C=CC(=O)Nc4ccccc4N)c3)cc2)cn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 4SC-202 has been used in trials studying the treatment of Advanced Hematologic Malignancies.
Molecule SMILES: Cn1cc(-c2ccc(S(=O)(=O)n3ccc(C=CC(=O)Nc4ccccc4N)c3)cc2)cn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Domatinostat is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. Domatinostat selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the selective transcription of tumor suppressor genes, and the tumor suppressor protein-mediated inhibition of tumor cell division and eventually the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, upregulated in many tumor types, are a class of enzymes that deacetylate chromatin histone proteins.
Molecule SMILES: CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1ccc(N)cc1.CC(C)c1nc(CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Prezcobix is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children who weigh at least 88 lb (40 kg) and meet certain requirements, as determined by a health care provider. Prezcobix is always used in combination with other HIV medicines.
Molecule SMILES: CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1ccc(N)cc1.CC(C)c1nc(CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Prezcobix contains two different medicines: darunavir and cobicistat.
Molecule SMILES: CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1ccc(N)cc1.CC(C)c1nc(CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Darunavir/Cobicistat is a fixed combination of darunavir, an inhibitor of the human immunodeficiency virus (HIV) protease; and cobicistat, a cytochrome P450 3A (CYP3A) inhibitor that may be used to treat HIV infection. Upon oral administration, darunavir binds to and inhibits the dimerization and catalytic activity of the HIV aspartyl protease. This inhibits the cleavage of HIV-encoded Gag and Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virions. Cobicistat inhibits CYP3A, thereby limiting the metabolism of darunavir and increases its systemic exposure.
Molecule SMILES: CC(=CCC(O)C(C)C1CCC2(C)C3CCC4C(C)(C)C(OC5OC(C)C(OC6OC(CO)C(O)C(O)C6O)C(O)C5OC5OC(C)C(O)C(O)C5O)CCC45CC35CCC12C)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: SquarrosideI is a natural product found in Thalictrum squarrosum with data available.
Molecule SMILES: C=C1C(=O)OC2C=C(C)C(OC(=O)C(C)CC)CC3OC3(C)CC(OC(=O)C3(C)OC3C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1R,2R,4R,6R,8S,9Z,11R)-4,9-dimethyl-8-[(2R)-2-methylbutanoyl]oxy-14-methylidene-13-oxo-5,12-dioxatricyclo[9.3.0.04,6]tetradec-9-en-2-yl] (2R,3R)-2,3-dimethyloxirane-2-carboxylate is a natural product found in Dendroviguiera eriophora and Dendroviguiera puruana with data available.
Molecule SMILES: CC1(C=O)CCC23COC4(CCC5C6(C)CCC(OC7OCC(OC8OC(CO)C(O)C(O)C8O)C(O)C7OC7OC(CO)C(O)C(O)C7O)C(C)(C)C6CCC5(C)C4(C)CC2O)C3C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Cyclaminorin is a natural product found in Ardisia mamillata, Cyclamen coum, and Cyclamen mirabile with data available.
Molecule SMILES: C=C1C2CCC3C45CCCC(C)(C)C4C(OC(C)=O)C(O)(OC5)C3(C1OC(C)=O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: rabdoternin C is a natural product found in Isodon ternifolius, Isodon rubescens, and Isodon xerophilus with data available.
Molecule SMILES: C=C(CCC=C(C)C)C1CCC2(C)C1CCC1C3(C)CCC(O)C(C)(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Dammaradienol is a natural product found in Ixeridium gracile, Taraxacum platycarpum, and other organisms with data available.