IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: OCC1CCCN2CCCCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Lupinine is a quinolizidine alkaloid.
Molecule SMILES: OCC1CCCN2CCCCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Lupinine is a natural product found in Plagiocarpus axillaris, Cristonia biloba, and other organisms with data available.
Molecule SMILES: COC(=O)C(C)CC(=O)CC(C)C1=CCC2(C)C3CCC4C(C)(CCC(O)C4(C)C)C3=CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: methyl (2R,6R)-6-[(3R,5S,8S,10S,13S,14S)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,12,15-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoate is a natural product found in Garcinia hombroniana and Garcinia celebica with data available.
Molecule SMILES: C=CC1C(OC2OC(CO)C(O)C(O)C2O)OC=C(C(=O)OC)C1CC=C(C=O)C1C(C(=O)OC)=COC(OC2OC(CO)C(O)C(O)C2O)C1C=C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (E)-Aldosecologanin is a natural product found in Lonicera japonica with data available.
Molecule SMILES: CC1OC(OC2CCC3(C)C4CCC5(C)C(C6=CC(=O)OC6)CCC5(O)C4CCC3(O)C2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Periplorhamnoside is a natural product found in Speirantha gardenii, Antiaris toxicaria, and other organisms with data available.
Molecule SMILES: C1=CC2C(CC3CCCCC32)NCCCNC2CC3CCCCC3C2C=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1R,2E,4E,6R,7S,12R,14S,20S,22R,27S)-15,19-diazapentacyclo[18.7.0.06,14.07,12.022,27]heptacosa-2,4-diene is a natural product found in Haliclona with data available.
Molecule SMILES: Cc1nc(CNS(=O)(=O)c2ccc(Oc3ccccc3)cc2)cs1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-[(2-methyl-4-thiazolyl)methyl]-4-phenoxybenzenesulfonamide is an aromatic ether.
Molecule SMILES: C=C1C(=O)OC2CC(C)C(CCC(C)=O)=CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Xanthalongin is a natural product found in Arnica longifolia, Dittrichia graveolens, and Inula japonica with data available.
Molecule SMILES: CC(C)=C1CC2(C)C(=CC1=O)CCC(OC1OC(CO)C(O)C(O)C1O)C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Isopetasoside is a terpene glycoside.
Molecule SMILES: CCCCCC=CCCC=CC=CC(=O)NCC(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Dihydrobungeanool is a natural product found in Zanthoxylum bungeanum and Zanthoxylum schinifolium with data available.
Molecule SMILES: CCCCCCCCOC1OC(C)C(OC(=O)CCCCC)C(OC2OC(C)C(OC(C)=O)C(O)C2OC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Mezzettiasideide 10 is a natural product found in Mezzettia parviflora with data available.
Molecule SMILES: CCCCCCCCCCCCC(O)C1(O)C(=O)CC(OC)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 23-Dihydroxy-2-(1-hydroxytridecyl)-4-met is a natural product found in Hygrophorus latitabundus with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)CCCn2cc(nn2)COC1CN(C)C(=O)C1CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylcyclopropanecarboxamide is an azamacrocycle and a lactam.
Molecule SMILES: COc1cc2c(cc1O)CCN1CCC3=CCC(OC)CC321

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Dihydroerysodine is a natural product found in Cocculus laurifolius with data available.
Molecule SMILES: CCC12CCCN3CCC4(c5ccccc5NC4CC1)C32

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Aspidospermidine is a natural product found in Aspidosperma pyrifolium and Vinca minor with data available.
Molecule SMILES: CCN1CC2(COC(=O)c3ccccc3N3C(=O)CC(C)C3=O)CCC(OC)C34C5CC6C(=O)C5C(O)(CC6OC)C(O)(C(OC)C23)C14

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (11-Ethyl-8,9-dihydroxy-6,16,18-trimethoxy-4-oxo-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-13-yl)methyl 2-(3-methyl-2,5-dioxopyrrolidin-1-yl)benzoate is a natural product found in Delphinium andersonii, Delphinium barbeyi, and other organisms with data available.
Molecule SMILES: O=C(OC1Cc2c(O)cc(O)c(C3c4ccc(O)cc4OC(c4cc(O)c(O)c(O)c4)C3O)c2OC1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(2R,3R)-8-[(2R,3S,4S)-3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate is a natural product found in Stryphnodendron adstringens with data available.
Molecule SMILES: CC1(CO)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (2R,3R,4S,4aR,6aR,6aS,6bR,8aS,10S,12aR,14bR)-2-(hydroxymethyl)-2,4a,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-3,4,10-triol is a natural product found in Abrus melanospermus with data available.
Molecule SMILES: CC(C)C1CCC2(C)CC3OOC12C=CC3(C)OO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1R,2R,5R,7S,8R)-8-hydroperoxy-5,8-dimethyl-2-propan-2-yl-11,12-dioxatricyclo[5.3.2.01,5]dodec-9-ene is a natural product found in Rosa rugosa with data available.
Molecule SMILES: CCN1CC2(COC)C(O)CC(OC)C34C5CC6(O)C(OC)CC(OC(C)=O)(C5C6OC(=O)c5ccc(OC)cc5)C(C(OC)C23)C14

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(2R,3R,5S,6S,8R,13R,17S)-8-acetyloxy-11-ethyl-5,14-dihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate is a natural product found in Aconitum sinomontanum, Aconitum bulleyanum, and other organisms with data available.
Molecule SMILES: CCCCCCCCCCCCCC=CC(O)C(N)COC1OC(COS(=O)(=O)O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Psychosine sulfate is a sulfoglycosphingolipid. It has a role as a human metabolite. It is functionally related to a psychosine. It is a tautomer of a psychosine sulfate zwitterion.
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(O)C1OC1OC(CO)C(O)C(OC2OC(CO)C(O)C(O)C2O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: N-[(2R,3R,4R,5S,6R)-4-[(2S,3S,4S,5R,6R)-3,5-Dihydroxy-6-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-2,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide is an amino sugar.
Molecule SMILES: CCC(C)C(=O)OCC=Cc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3-Phenylallyl 2-methylbutyrate is a natural product found in Artemisia salsoloides with data available.
Molecule SMILES: COc1ccc(C(C)=O)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2,4-Dimethoxyacetophenone is an aromatic ketone.
Molecule SMILES: CCCCCCCCCCCC(O)CC(O)CCc1ccc(OC)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Methyl-[12]-gingerdiol is a natural product found in Zingiber officinale with data available.
Molecule SMILES: Cc1ccc(C2(C)CCCC2(C)C)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 1-Methyl-4-(1,2,2-trimethylcyclopentyl)benzene is a natural product found in Hypericum scabrum, Juniperus occidentalis, and other organisms with data available.
Molecule SMILES: COC1CCN2OC3C=CC4=CC(=O)OC4(C3)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: securinega amamine D is a natural product found in Flueggea suffruticosa with data available.
Molecule SMILES: CC(O)C1C(O)CC2C3CCC4CC(O)CCC4(C)C3CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 5-beta-Pregnane-3-beta,16-beta,20-alpha-triol is a natural product found in Cipadessa baccifera with data available.
Molecule SMILES: C=C1C(=O)OC2C3OC3(C)CCC=C(C)CC(OC(=O)C3(C)OC3C)C12O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [(1R,2R,4S,7E,10R,11S)-11-hydroxy-4,8-dimethyl-12-methylidene-13-oxo-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-10-yl] (2S,3R)-2,3-dimethyloxirane-2-carboxylate is a natural product found in Montanoa guatemalensis with data available.
Molecule SMILES: CSCCC(=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 4-methylthio-2-oxobutanoic acid is a 2-oxo monocarboxylic acid derived from L-methionine via the action of methionine transaminase. It is functionally related to a butyric acid and a L-methionine. It is a conjugate acid of a 4-methylthio-2-oxobutanoate.
Molecule SMILES: CSCCC(=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2-Oxo-4-methylthiobutanoic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: CSCCC(=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 4-Methylthio-2-oxobutanoate is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: CSCCC(=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 4-(Methylsulfanyl)-2-oxobutanoic acid is a natural product found in Euglena gracilis, Arabidopsis thaliana, and other organisms with data available.
Molecule SMILES: CCC1OC2Oc3c(C)c(O)c(C)c4c3C(CC(c3ccc(OC)cc3)O4)OC2C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Eruberin A is an organic heterotetracyclic compound resulting from cyclocondensation of the 4- and 5-hydroxy groups of (2R,4S)-2-(4-methoxyphenyl)-6,8-dimethyl-3,4-dihydro-2H-chromene-4,5,7-triol across the 1- and 2-positions of beta-D-glucopyranose. It is a natural product extracted from the fern plant, Pronephrium penangianum and exerts antiproliferative and antifibrotic activity. It has a role as an antioxidant and a plant metabolite. It is an organic heterotetracyclic compound, a polycyclic ether, a member of methoxybenzenes, a monosaccharide derivative and a hydroxyflavan. It is functionally related to a beta-D-glucose.
Molecule SMILES: CC1=C(C=O)CC2C1(C)CCC(C)C2(C)CC(O)C1=CC(=O)OC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Pentandralactone is a natural product found in Callicarpa pentandra with data available.
Molecule SMILES: O=C(c1ccccn1)N(Cc1cccs1)C1(C(=O)NC2CCCCC2)CCCCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(thiophen-2-ylmethyl)-2-pyridinecarboxamide is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Molecule SMILES: C[N+]1=CNCC1(C)CC(NC(=O)c1cc(Br)c[nH]1)C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: clathramide B is a natural product found in Agelas clathrodes with data available.
Molecule SMILES: CC1OC(OCC2OC(Oc3c(-c4ccc(O)cc4)oc4cc(O)cc(O)c4c3=O)C(O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Kaempferol-3-rutinoside is a kaempferol O-glucoside that is kaempferol attached to a rutinosyl [6-deoxy-alpha-L-mannosyl-(1->6)-beta-D-glucosyl] residue at position 3 via a glycosidic linkage. It has been isolated from the leaves of Solanum campaniforme. It has a role as a metabolite, a radical scavenger and a plant metabolite. It is a rutinoside, a trihydroxyflavone, a disaccharide derivative and a kaempferol O-glucoside.
Molecule SMILES: CC1OC(OCC2OC(Oc3c(-c4ccc(O)cc4)oc4cc(O)cc(O)c4c3=O)C(O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Nicotiflorin is a natural product found in Visnea mocanera, Eupatorium cannabinum, and other organisms with data available.
Molecule SMILES: CC(C)C(O)(C(=O)OC1CCN2CC=C(CO)C12)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Tessellatine is a natural product found in Amsinckia menziesii, Amsinckia grandiflora, and other organisms with data available.
Molecule SMILES: CC(=O)OCC(=CCCC(C)=CCO)CCCC(C)C1CC(O)C(C)(C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(2Z,6E)-8-hydroxy-2-[(4R)-4-[(2S,4R)-4-hydroxy-5,5-dimethyloxolan-2-yl]pentyl]-6-methylocta-2,6-dienyl] acetate is a natural product found in Carpesium triste with data available.
Molecule SMILES: Cc1c2c(O)c3c(cc2cc(=O)n1CCO)C(=O)c1cccc(O)c1C3=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Pyxidicycline A is a natural product found in Pyxidicoccus fallax with data available.
Molecule SMILES: CC1=CCC(C(=O)Oc2c(O)c(-c3ccc(O)cc3)c(OC(=O)CC(C)OC(=O)O)c(O)c2-c2ccc(O)cc2)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [4-[(3S)-3-carboxyoxybutanoyl]oxy-2,5-dihydroxy-3,6-bis(4-hydroxyphenyl)phenyl] 3-methylcyclopent-3-ene-1-carboxylate is a natural product found in Sphingopyxis with data available.
Molecule SMILES: CC1(C)Oc2c(O)cc(C=CC(=O)c3ccc(O)cc3O)cc2C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Abyssinone C is a chromenol that is 2,2-dimethyl-3,4-dihydro-2H-chromene-3,4,8-triol substituted by a 3-(2,4-dihydroxyphenyl)-3-oxoprop-1-en-1-yl moiety at position 6 (the E-isomer). It is isolated from the stems of Erythrina abyssinica and displays moderate cytotoxic effect against human colorectal cancer cell line. It has a role as a metabolite and an antineoplastic agent. It is a member of chalcones, a member of resorcinols and a chromenol.
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)c1c(O)cc(OC2OC(CO)C(O)C(O)C2O)cc1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Chalconaringenin 2',4'-di-O-glucoside is a member of flavonoids and a glycoside.
Molecule SMILES: O=c1oc2cc(O)ccc2c(O)c1-c1ccc(OC2OC(CO)C(O)C(O)C2O)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Asphodelin A-4'-O-beta-glucoside is a beta-D-glucoside in which a beta-D-glucopyranosyl residue is attached at position 4' of asphodelin A via a glycosidic linkage. It is isolated from the roots of Asphodelus microcarpus and exhibits antimicrobial activity against bacteria like Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and fungal microorganisms like Candida albicans and Botrytis cinerea. It has a role as a metabolite, an antibacterial agent and an antifungal agent. It is a beta-D-glucoside, a hydroxycoumarin and a polyphenol. It is functionally related to an asphodelin A.
Molecule SMILES: O=c1oc2cc(O)ccc2c(O)c1-c1ccc(OC2OC(CO)C(O)C(O)C2O)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: asphodelin A-4'-O-beta-glucoside is a natural product found in Asphodelus tenuifolius, Asphodelus fistulosus, and Asphodelus aestivus with data available.
Molecule SMILES: COc1ccc2cc1Oc1ccc(cc1)CC1c3c(cc(OC)c4c3Oc3cc5c(cc3O4)CCN=C5C2)CCN1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (+)-1,2-Dehydrotelobine is a natural product found in Daphnandra apatela, Stephania erecta, and Stephania pierrei with data available.
Molecule SMILES: [NH2-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Azanide is a nitrogen hydride and a monovalent inorganic anion. It is a conjugate base of an ammonia. It is a conjugate acid of a hydridonitrate(2-).
Molecule SMILES: CCCNC(=O)Nc1ccc2c(c1)C(=O)N(C)CC(OC)C(C)CN(Cc1ccncc1)C(C)CO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 1-[(4R,7S,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-(pyridin-4-ylmethyl)-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-3-propylurea is a lactam and an azamacrocycle.
Molecule SMILES: O=C1c2ccccc2C(=O)C1c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Phenindione is a beta-diketone and an aromatic ketone. It has a role as an anticoagulant. It derives from a hydride of an indane.
Molecule SMILES: O=C1c2ccccc2C(=O)C1c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)
Molecule SMILES: O=C1c2ccccc2C(=O)C1c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Phenindione is only found in individuals that have used or taken this drug. It is an indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234). Phenindione inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins, this limits the gamma-carboxylation and subsequent activation of the vitamin K-dependent coagulant proteins. The synthesis of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Depression of three of the four vitamin K-dependent coagulation factors (factors II, VII, and X) results in decreased prothrombin levels and a decrease in the amount of thrombin generated and bound to fibrin. This reduces the thrombogenicity of clots.