IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: O=[N+]([O-])c1ccc(-c2nc(N(CCO)CCO)c3ccccc3n2)o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Nifurquinazol is a nitrofuran derivative with antibacterial activity.
Molecule SMILES: OCC1OC(OCCc2ccc(O)cc2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (3R,4S,5S,6R)-2-[2-(2,4-dihydroxyphenyl)ethoxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a natural product found in Olea europaea with data available.
Molecule SMILES: CCOC(=O)c1cc(O)c(OC)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3,5-Dihydroxy-4-methoxybenzoic acid ethyl ester is a natural product found in Stocksia brahuica with data available.
Molecule SMILES: O=C(O)CC(=O)OCC1OC(Oc2cc3c(O)cc(O)cc3[o+]c2-c2cc(OC3OC(CO)C(O)C(O)C3O)c(O)c(OC3OC(COC(=O)C=Cc4ccc(OC5OC(CO)C(O)C(O)C5O)cc4)C(O)C(O)C3O)c2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 3-[[(2S,3S,4S,5S,6S)-6-[5,7-dihydroxy-2-[4-hydroxy-3-[(2S,3R,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(E)-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-enoyl]oxymethyl]oxan-2-yl]oxyphenyl]chromenylium-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-3-oxopropanoic acid is a natural product found in Clitoria ternatea with data available.
Molecule SMILES: C=CC(C)(C)C12C=C(O)C(=O)N3C(C)C(=O)NC31N(O)c1ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Versiquinazoline Q is a natural product found in Aspergillus versicolor with data available.
Molecule SMILES: Brc1cc(Br)c(Br)c(-c2c(Br)ccc(Br)c2Br)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2,2',3,3',5,6'-Hexabromobiphenyl is a polybrominated biphenyl. Polybrominated biphenyls (PBBs) are a group of 209 synthetic organic compounds with 1-10 bromine atoms attached to biphenyl. They can be used as flame retardants and may be added to the plastics used to make products like computer monitors, televisions, textiles, and plastic foams to make them difficult to burn. However, the use of PBBs is banned or restricted in most areas due to their toxicity and persistence in the environment. (L628, L629)
Molecule SMILES: COC(=O)CC(C(C)=O)c1cc(=O)c2c(O)cc(O)cc2o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: methyl (3R)-3-(5,7-dihydroxy-4-oxochromen-2-yl)-4-oxopentanoate is a natural product found in Chamaecyparis pisifera with data available.
Molecule SMILES: COc1c(CC=C(C)C)cc2ccc(=O)oc2c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 8-Hydroxy-7-methoxy-6-(3-methylbut-2-enyl)chromen-2-one is a natural product found in Zanthoxylum beecheyanum, Brosimum rubescens, and other organisms with data available.
Molecule SMILES: CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(OC7OC(C)C(OC8OC(CO)C(O)C(O)C8O)C(O)C7O)C6OC6OC(CO)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Melongoside M is a natural product found in Solanum melongena with data available.
Molecule SMILES: CCCCCCCCC(=O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-oxodecanoic acid is a 2-oxo monocarboxylic acid that is decanoic acid carrying an oxo group at position 2. It has a role as an algal metabolite and a plant metabolite. It is functionally related to a decanoic acid. It is a conjugate acid of a 2-oxodecanotate.
Molecule SMILES: O=C1c2ccccc2-c2cc([N+](=O)[O-])ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 3-nitro-9-fluorenone is a solid. (NTP, 1992)
Molecule SMILES: c1ncc(-c2ccc(C3C4CN(Cc5ccc6c(c5)OCO6)CC3N4)cc2)cn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1R,5S)-3-(1,3-benzodioxol-5-ylmethyl)-7-[4-(5-pyrimidinyl)phenyl]-3,6-diazabicyclo[3.1.1]heptane is a member of pyrimidines.
Molecule SMILES: CC(=O)OC1CC(OC(C)=O)C2(C)C(OC(C)=O)CC(O)C(C)(O)C2C(OC(C)=O)C23OC2(C)C(=O)OC3C=C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1R,2R,3R,4R,5R,7R,8S,9R,11S,12Z,14R,17S)-2,7,9-triacetyloxy-4,5-dihydroxy-4,8,12,17-tetramethyl-16-oxo-15,18-dioxatetracyclo[12.4.0.01,17.03,8]octadec-12-en-11-yl] acetate is a natural product found in Briareum stechei with data available.
Molecule SMILES: Cc1cc(O)cc(O)c1C(=O)OC1CC2=C(COC(C=CCO)=C2)C(=O)C1(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Entonaemin A is a natural product found in Hypoxylon rubiginosum and Hypoxylon rutilum with data available.
Molecule SMILES: CCC(C)C(=O)OC1C2(C)CC3(OC(=O)C(C)CC)C1(O)C(=O)C1=C4CC(=O)OC(c5ccoc5)C4(C)CCC1C3(C)C2CC(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(1R,2S,5S,6R,13S,14R,15S,17S,18S)-6-(furan-3-yl)-13-hydroxy-18-(2-methoxy-2-oxoethyl)-1,5,15-trimethyl-17-[(2S)-2-methylbutanoyl]oxy-8,12-dioxo-7-oxapentacyclo[13.2.1.02,11.05,10.013,17]octadec-10-en-14-yl] (2S)-2-methylbutanoate is a natural product found in Xylocarpus moluccensis with data available.
Molecule SMILES: C=CC12COC(=O)C(=C)C1C1OC(=O)C(C)C1C(OC(=O)C(=C)CO)C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: [(3S,3aR,4S,5aS,9aR,9bR)-5a-ethenyl-3-methyl-9-methylidene-2,8-dioxo-3a,4,5,6,9a,9b-hexahydro-3H-furo[2,3-f]isochromen-4-yl] 2-(hydroxymethyl)prop-2-enoate is a natural product found in Gymnanthemum amygdalinum with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)CCCn2cc(nn2)COC1CN(C)C(=O)NC1CCCCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-cyclohexyl-1-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methylurea is a lactam and an azamacrocycle.
Molecule SMILES: CCCCC=CCCCCCCCCOC(=O)CCCCCCCC=CCC=CCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Myristoleyl linoleate is a wax ester.
Molecule SMILES: CCCCCCCCCC(=O)NC(C(=O)NC(CCN)C(=O)NC(C(=O)NCC(=O)NC(CCCN(O)C(=O)CC(C)O)C(=O)O)C(O)C(=O)O)C(O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Cupriachelin is a natural product found in Cupriavidus necator with data available.
Molecule SMILES: CC(=O)NCC(C)CCC(=O)C(C)C1C(O)CC2C3CCC4CC(OC5OC(CO)C(OC6OC(C)C(O)C(O)C6OC6OCC(O)C(O)C6O)C(O)C5O)CCC4(C)C3CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-[(2S,6S)-6-[(3S,5S,8R,9S,10S,13S,14S,16R,17R)-3-[(2R,3R,4S,5S,6R)-5-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-16-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxoheptyl]acetamide is a natural product found in Solanum abutiloides with data available.
Molecule SMILES: Cc1ccc2c(c1)OC1(C)C(C)CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Debromoaplysin is a natural product found in Laurencia okamurae, Erythrocystis saccata, and other organisms with data available.
Molecule SMILES: CC1CCC2(C)CCC3(C)C(=CC=C4C5(C)CCC(=O)C(C)(C)C5CCC43C)C2C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Marsformosanone is a natural product found in Marsdenia formosana and Diospyros malabarica with data available.
Molecule SMILES: OCC1OC(OC2C(CO)OC(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Beta-D-Galp-(1->3)-alpha-L-Araf is a beta-D-Galp-(1->3)-L-Araf in which the carbon bearing the anomeric hydroxy group has alpha configuration. It is functionally related to a beta-D-galactose and an alpha-L-arabinofuranose.
Molecule SMILES: COc1ccccc1C1COc2cc(C)ccc2C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Conferol B is a member of the class of isoflavans that is isoflavan with a hydroxy group at position 4, a methyl group at position 7 and a methoxy group at position 2' (the 3R,4S stereoisomer). It is isolated from Caragana conferta and exhibits significant anti-inflammatory activity in the respiratory burst assay. It has a role as a metabolite and an anti-inflammatory agent. It is a secondary alcohol, a monomethoxybenzene, a member of hydroxyisoflavans and a methoxyisoflavan.
Molecule SMILES: COc1ccccc1C1COc2cc(C)ccc2C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Conferol B is a natural product found in Caragana conferta with data available.
Molecule SMILES: CNCC1Oc2ccc(NC(=O)Nc3ccc4c(c3)OCO4)cc2CC(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 1-(1,3-benzodioxol-5-yl)-3-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea is a member of benzodioxoles.
Molecule SMILES: Cc1cccc(Nc2nn3c(=O)c4ccccc4nc3s2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2-(3-methylanilino)-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one is a member of quinazolines.
Molecule SMILES: CCCCCCCC1=CC2=CC(=O)OC2C(C)(O)C1(O)C(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ankalactone is a natural product found in Monascus purpureus with data available.
Molecule SMILES: CC1OC(OC2C(Oc3cc(O)c4c(=O)cc(-c5ccc(O)c(O)c5)oc4c3)OC(COC(=O)CC(=O)O)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 3-[[6-[2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxochromen-7-yl]oxy-3,4-dihydroxy-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]methoxy]-3-oxopropanoic acid is a natural product found in Bryum pseudotriquetrum with data available.
Molecule SMILES: Clc1cccc(Nc2c3c(nc4ncnn24)CCC3)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: LSM-34798 is a member of triazolopyrimidines.
Molecule SMILES: NCCCCC(N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Lys-Tyr is a dipeptide formed from L-lysine and L-tyrosine residues. It has a role as a metabolite. It is functionally related to a L-lysine and a L-tyrosine.
Molecule SMILES: NCCCCC(N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Lys-Tyr is a natural product found in Trypanosoma brucei and Homo sapiens with data available.
Molecule SMILES: CC=C1CN2C3CC45c6cc(OC)cc(OC)c6NC4(O3)C2CC1C5C(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Tabernulosine is a natural product found in Tabernaemontana glandulosa with data available.
Molecule SMILES: CC1CC2CCC(O2)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)OC(C)CC2CCC(O2)C(C)C(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Nonactin is a natural product found in Streptomyces globisporus and Streptomyces griseus with data available.
Molecule SMILES: COc1cc(CCc2cccc(O)c2)cc(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3,5-Dimethoxy-3'-hydroxybibenzyl is a natural product found in Bletilla ochracea with data available.
Molecule SMILES: CC(C)C1=C2CCC3(C)C(CCC4C5(C)CCCC(C)(C)C5CCC43C)C2(C)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5a,5b,8,8,11a,13b-Hexamethyl-3-propan-2-yl-1,2,4,5,6,7,7a,9,10,11,11b,12,13,13a-tetradecahydrocyclopenta[a]chrysene is a natural product found in Goniophlebium niponicum with data available.
Molecule SMILES: O=C(OC1OC(CO)C(O)C(O)C1O)C(CO)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (2R)-3-hydroxy-2-phenylpropanoate is a natural product found in Panax ginseng with data available.
Molecule SMILES: COc1ccc(N2CC(CO)OC2=O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 5-Hydroxymethyl-3-(p-methoxyphenyl)-2-oxazolidinone is a natural product found in Streptomyces with data available.
Molecule SMILES: C=C1CC(O)C2C(CNC(C(=O)O)C(C)CC)C(=O)OC2C2C(=C)C(O)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: pulchellamine G is a natural product found in Saussurea pulchella with data available.
Molecule SMILES: Brc1cc(Br)c(-c2cc(Br)ccc2Br)c(Br)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2,2',4,5',6-Pentabromobiphenyl is a polybrominated biphenyl. Polybrominated biphenyls (PBBs) are a group of 209 synthetic organic compounds with 1-10 bromine atoms attached to biphenyl. They can be used as flame retardants and may be added to the plastics used to make products like computer monitors, televisions, textiles, and plastic foams to make them difficult to burn. However, the use of PBBs is banned or restricted in most areas due to their toxicity and persistence in the environment. (L628, L629)
Molecule SMILES: COc1cc(O)c2c(=O)c3cccc(OC)c3oc2c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 1-Hydroxy-3,4,5-trimethoxyxanthone is a natural product found in Garcinia dulcis and Lomatogonium carinthiacum with data available.
Molecule SMILES: COC1CC(OC2C(C)C(=O)OC(C)C(C)C(O)C(C)C(=O)C3(CO3)CC(C)C(OC3OC(C)CC(N(C)C)C3O)C2C)OC(C)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Oleandomycin is a macrolide antibiotic similar to erythromycin with antimicrobial activity. Oleandomycin targets and reversibly binds to the 50S subunit of bacterial ribosomes. This prevents translocation of peptidyl tRNA leading to an inhibition of protein synthesis.
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Myleran appears as white crystals or powder. (NTP, 1992)
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Busulfan is an orally administered anticancer alkylating agent used in the treatment of chronic myelogenous leukemia, as well as a parenterally administered myeloablative agent used in preparation of hematopoietic cell transplantation (HCT). Busulfan has been linked to transient serum enzyme elevations during therapy, to rare cases of cholestatic hepatitis, instances of nodular regenerative hyperplasia and, when given in high doses, to sinusoidal obstruction syndrome which can be severe and fatal.
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Busulfan is a methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. It has a role as an insect sterilant, an antineoplastic agent, a teratogenic agent, a carcinogenic agent and an alkylating agent. It is functionally related to a butane-1,4-diol.
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Busulfan is an Alkylating Drug. The mechanism of action of busulfan is as an Alkylating Activity.
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties.  Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA.  Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription. (NCI04)
Molecule SMILES: CS(=O)(=O)OCCCCOS(C)(=O)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Molecule SMILES: CC=CCCCCC1=C(C)C(=O)N2CCC(=NO)C2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2-[(E)-5-Heptenyl]-3-methyl-8-(hydroxyimino)-6,7,8,8a-tetrahydro-4H-pyrrolo[2,1-b][1,3]oxazine-4-one is a natural product found in Penicillium brevicompactum with data available.
Molecule SMILES: CC1=C2CCC3(C)C(CC=C4C5CC(C)(C)CCC5C(=O)CC43C)C2(C)C=C(O)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (6aR,6bS,8aS,12aR,14aS,14bR)-2-hydroxy-4,6a,6b,11,11,14b-hexamethyl-5,6,7,8a,9,10,12,12a,14,14a-decahydropicene-3,8-dione is a natural product found in Physena madagascariensis with data available.