IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC1C=CC=CC(C)C2C=CC3CCCC(C)C3C2C(O)=CC(=O)CC(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Chlorotonil C2 is a natural product found in Sorangium cellulosum with data available.
Molecule SMILES: N#CC1(OC2OC(CO)C(O)C(O)C2O)C=CC(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1R,4R,5S)-4,5-dihydroxy-1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclopent-2-ene-1-carbonitrile is a natural product found in Ceratiosicyos laevis with data available.
Molecule SMILES: CC1=CCCC2C1(C)CCC(C)C2(C)C=CC1=CC(=O)OC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (2S)-3-[(E)-2-[(1R,2R,4aR,8aR)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]ethenyl]-2-hydroxy-2H-furan-5-one is a natural product found in Callicarpa americana with data available.
Molecule SMILES: CC(=O)C1C(O)CC2C3CCC4C(C)(C)CCCC4(CO)C3CC3OC(=O)C1C32C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (1S,5S,10S,11S,13R,16S,17S,18S,20S)-17-acetyl-18-hydroxy-10-(hydroxymethyl)-6,6,20-trimethyl-14-oxapentacyclo[11.6.1.02,11.05,10.016,20]icosan-15-one is a natural product found in Lendenfeldia with data available.
Molecule SMILES: C=C1CC2OC3C4C(CC(C)C(OC(C)=O)C24)C(C)COC3(C)CCC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(1S,2S,3R,4R,5R,7S,8R,11S,14R,17S)-14-hydroxy-5,8,11-trimethyl-15-methylidene-10,18-dioxatetracyclo[9.7.0.02,7.03,17]octadecan-4-yl] acetate is a natural product found in Briareum asbestinum with data available.
Molecule SMILES: O=C([O-])CC([O-])(CC(=O)[O-])C(=O)[O-].O=C([O-])CC([O-])(CC(=O)[O-])C(=O)[O-].[Bi+3].[K+].[K+].[K+].[K+].[K+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Molecule SMILES: O=C([O-])CC([O-])(CC(=O)[O-])C(=O)[O-].O=C([O-])CC([O-])(CC(=O)[O-])C(=O)[O-].[Bi+3].[K+].[K+].[K+].[K+].[K+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Bismuth Subcitrate Potassium is a soluble, complex bismuth salt of citric acid used in combination with metronidazole and tetracycline to treat stomach ulcers caused by Helicobacter pylori infections.
Molecule SMILES: COc1c(O)cc(C2Oc3cc(O)cc(OC4OC(CO)C(O)C(O)C4O)c3CC2O)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S,3R,4S,5S,6R)-2-[(2R,3R)-2-(3,5-dihydroxy-4-methoxy-phenyl)-3,7-dihydroxy-chroman-5-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol is a natural product found in Gymnosporia senegalensis with data available.
Molecule SMILES: COC1=CC2Oc3cc(OC)cc(C)c3C(=O)C2C(O)=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (4aS,9aS)-1-hydroxy-3,6-dimethoxy-8-methyl-4a,9a-dihydroxanthen-9-one is a natural product found in Ruprechtia tangarana with data available.
Molecule SMILES: CC(=O)C1CCC2C3CC(C)C4=CC(=O)CCC4(C)C3C(O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Medrysone is a corticosteroid hormone.
Molecule SMILES: CC(=O)C1CCC2C3CC(C)C4=CC(=O)CCC4(C)C3C(O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Medrysone is a corticosteroid used in ophthalmology.
Molecule SMILES: CC(=O)C1CCC2C3CC(C)C4=CC(=O)CCC4(C)C3C(O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Medrysone is a Corticosteroid. The mechanism of action of medrysone is as a Corticosteroid Hormone Receptor Agonist.
Molecule SMILES: CC(=O)C1CCC2C3CC(C)C4=CC(=O)CCC4(C)C3C(O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Medrysone is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions is accomplished.
Molecule SMILES: CCCCCC1OC1C=CC(=O)NCC(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (E)-N-(2-methylpropyl)-3-[(2R,3R)-3-pentyloxiran-2-yl]prop-2-enamide is a natural product found in Piper nigrum with data available.
Molecule SMILES: COc1ccc(CCc2cc(=O)c3cc(OC)ccc3o2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 4H-1-Benzopyran-4-one, 6-methoxy-2-(2-(4-methoxyphenyl)ethyl)- is a natural product found in Aquilaria malaccensis with data available.
Molecule SMILES: CC1(C)CC2C(O)C3=C(COC3=O)CC(C)(O)C2C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 5-Desoxylactarolide B is a natural product found in Lactifluus subvellereus with data available.
Molecule SMILES: CC1OC(Oc2c(-c3cc(O)c(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)C(OC(=O)c2cc(O)c(O)c(O)c2)C(OC(=O)c2cc(O)c(O)c(O)c2)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: [(2S,3S,4R,5S,6R)-2-[5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)chromen-3-yl]oxy-5-hydroxy-6-methyl-3-(3,4,5-trihydroxybenzoyl)oxyoxan-4-yl] 3,4,5-trihydroxybenzoate is a natural product found in Acacia confusa with data available.
Molecule SMILES: CCC(CCC(C)C1CCC2C3C(=O)C=C4CC(O)CCC4(C)C3CCC12C)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (3S,8S,9R,10S,13R,14S,17S)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one is a natural product found in Globba racemosa with data available.
Molecule SMILES: CC(O)=C1C(=O)C2C3c4c[nH]c5cccc(c45)CC3C(C)(C)N2C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (2R,3R,5Z,9R)-5-(1-hydroxyethylidene)-8,8-dimethyl-7,16-diazapentacyclo[9.6.1.02,9.03,7.015,18]octadeca-1(17),11(18),12,14-tetraene-4,6-dione is a natural product found in Aspergillus flavus with data available.
Molecule SMILES: COc1cccc(O)c1-c1cc(=O)c2c(O)c(C)c(C)c(C)c2o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 5-Hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethylchromen-4-one is a natural product found in Scutellaria baicalensis with data available.
Molecule SMILES: O=C(Nc1cccc2cccnc12)c1ccc(N2C(=O)C3C4C=CC(C4)C3C2=O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: IWR-1-exo is a dicarboximide having an exo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It is a weak axin stabilizer, an analogue of IWR-1-endo. It has a role as an axin stabilizer. It is a dicarboximide and a bridged compound.
Molecule SMILES: CC(=O)C(C)C(O)C(C)c1ccc(C)cc1C=CCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: CID 11778214 is a natural product found in Streptomyces pactum with data available.
Molecule SMILES: COc1ccc(C2CC(=O)c3c(cc(O)c(CC=C(C)CCC=C(C)C)c3O)O2)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (2S)-3',4'-Dimethoxy-5,7-dihydroxy-6-[(2E)-3,7-dimethyl-2,6-octadienyl]-2,3-dihydroflavone is a natural product found in Paulownia tomentosa with data available.
Molecule SMILES: O=C1C(Cc2ccccc2)CCn2cc(nn2)COCC2CCCN12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: LSM-37278 is a lactam and an azamacrocycle.
Molecule SMILES: CC1=C2N=C(C=C3NC(=Cc4[nH]c(c(CCC(=O)O)c4CC(=O)O)Cc4[nH]c1c(CC(=O)O)c4CCC(=O)O)C(CCC(=O)O)C3(C)CC(=O)O)C(CCC(=O)O)C2(C)CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Precorrin-3A is the intermediate in the biosynthesis of vitamin B12 from uroporphyrinogen III in which three methyl groups have been introduced at positions 2, 7 and 20 of the tetrapyrrole framework. It is a conjugate acid of a precorrin-3A(7-).
Molecule SMILES: CC1=CC2OC3CC(O)C(C)(C2(CO)CC1)C31CO1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Verrucarol is a trichothecene. Trichothecenes are a very large family of chemically related mycotoxins produced by various species of Fusarium, Myrothecium, Trichoderma, Trichothecium, Cephalosporium, Verticimonosporium, and Stachybotrys. The most important structural features causing the biological activities of trichothecenes are: the 12,13-epoxy ring, the presence of hydroxyl or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain. They are produced on many different grains like wheat, oats or maize by various Fusarium species such as F. graminearum, F. sporotrichioides, F. poae and F. equiseti. Some molds that produce trichothecene mycotoxins, such as Stachybotrys chartarum, can grow in damp indoor environments and may contribute to health problems among building occupants. (L1948)
Molecule SMILES: CC=C(C)C(=O)OC1C(OC(=O)C(C)C)CC2(C)C3C(=O)C=C(C)C2C3C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1R,2S,4S,5S,7R,8R)-3,3,7,9-tetramethyl-5-(2-methylpropanoyloxy)-11-oxo-4-tricyclo[5.4.0.02,8]undec-9-enyl] (Z)-2-methylbut-2-enoate is a natural product found in Stevia serrata with data available.
Molecule SMILES: COc1cc2c(OC3OCC(O)(COC4OCC(O)C(O)C4O)C3OC3OCC(O)C(O)C3O)c3c(c(-c4ccc5c(c4)OCO5)c2cc1OC)C(=O)OC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Ciliatoside A is a natural product found in Monechma ciliatum with data available.
Molecule SMILES: CCCCCCCCCCCCCCC(O)C(O)C(COC1OC(CO)C(O)C(O)C1O)NC(=O)CCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 1-O-(alpha-D-galactopyranosyl)-N-dodecanoylphytosphingosine is a glycophytoceramide having an alpha-D-galactopyranosyl residue at the O-1 position and a dodecanoyl group attached to the nitrogen. It is functionally related to an alpha-D-galactose and a dodecanoic acid.
Molecule SMILES: CCC(C)C(=O)N1CCCNC(=O)CC(c2ccc(OC3OC(C)C(O)C(O)C3OC3OC(COC(=O)c4ccccc4)C(O)C(O)C3O)cc2)NCCC(OC(C)=O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [(2R,3S,4S,5R,6S)-6-[(2S,3R,4R,5R,6S)-2-[4-[(2R,11S)-11-acetyloxy-9-[(2S)-2-methylbutanoyl]-4-oxo-1,5,9-triazacyclotridec-2-yl]phenoxy]-4,5-dihydroxy-6-methyloxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl benzoate is a natural product found in Meehania urticifolia with data available.
Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCCCC(=O)OCC(O)COCC=Cc1ccc(OC)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 1-Isoferulyl-3-pentacosanoyl glycerol is a natural product found in Tamarix aphylla with data available.
Molecule SMILES: CC=C(C)C(=O)OC1C2=CC(=O)C(C)(OC(C)=O)C(=O)C2=COC12CC(C)CCC2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(2'R,3R,4R,5'S,7S)-7-acetyloxy-2'-hydroxy-5',7-dimethyl-6,8-dioxospiro[4H-isochromene-3,1'-cyclohexane]-4-yl] (E)-2-methylbut-2-enoate is a natural product found in Hypoxylon rubiginosum with data available.
Molecule SMILES: CCC(N)Cc1c[nH]c2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Etryptamine is a member of indoles.
Molecule SMILES: CCC(N)Cc1c[nH]c2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and the drug was withdrawn from potential market use.   In 1993, the US Drug Enforcement Administration added αET to Schedule I of its Schedules of Controlled Substances, after an increasing incidence of its use as a recreational drug in the 1980's. Currently, αET is an illegal substance; however, it's activity is still under scientific investigation.   αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine, a closely related compound. Instead, the effects of αET, a tryptamine derivative, more closely resemble the amphetamine derived drug 3,4-methylenedioxy-N-methylamphetamine (MDMA). Similarly to MDMA, αET has been shown to release serotonin pre-synaptically, as well as lesser amounts of norepinephrine and dopamine. Like MDMA, increases in locomotor activity and mood elevation can be seen post administration.
Molecule SMILES: CC1(C)CCC2(COC3OC(CO)C(O)C(O)C3O)C(O)CC3(C)C(=CCC4C5(C)CCC(O)C(C)(COC6OC(COC7OC(CO)C(O)C(O)C7O)C(O)C(O)C6O)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Gymnemasaponin IV is a natural product found in Gymnema sylvestre with data available.
Molecule SMILES: CC=C(C)C=C(C)c1cc(OC)c(C)c(=O)o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Phomapyrone A is a natural product found in Leptosphaeria maculans with data available.
Molecule SMILES: C=C1c2[nH]c3ccccc3c2CCN2CCC1(O)C(=CC)C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (1S,16Z)-16-ethylidene-2-methylidene-4,14-diazatetracyclo[12.2.2.03,11.05,10]octadeca-3(11),5,7,9-tetraen-1-ol is a natural product found in Aspidosperma subincanum with data available.
Molecule SMILES: CCC(=O)Nc1ccc2c(c1)C(=O)N(C)CC(OC)C(C)CN(Cc1cccnc1)C(C)CO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-[(4R,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-(3-pyridinylmethyl)-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide is a lactam and an azamacrocycle.
Molecule SMILES: CCCCCC=CCC(O)C=CC=CC=CC(O)CCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (5S,8E,10E,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid is a natural product found in Phaseolus vulgaris with data available.
Molecule SMILES: COCC(=O)N1CC2(C1)CN(S(C)(=O)=O)C(CO)c1[nH]c3cc(OC)ccc3c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 1-[(1R)-1-(hydroxymethyl)-7-methoxy-2-methylsulfonyl-1'-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]yl]-2-methoxyethanone is a harmala alkaloid.
Molecule SMILES: C=CC1C2=C(C(=O)OCC2)C(OC)OC1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Swertiajaposide A is a natural product found in Swertia japonica and Gentiana scabra with data available.
Molecule SMILES: CC(=O)OCCC(C)CCC1C(C)=CCC2C(C)(C)CC(OC(C)=O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(3S)-5-[(1R,4aR,7R,8aR)-7-acetyloxy-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]-3-methylpentyl] acetate is a natural product found in Baccharis latifolia with data available.
Molecule SMILES: CCCCCCCCC(C)=CCc1oc(C(C)=O)c(C)c(=O)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-Acetyl-3,5-dimethyl-6-(3-methylundec-2-enyl)pyran-4-one is a natural product found in Verticillium with data available.
Molecule SMILES: CC1(C)C(Cl)CC23C4CC(=O)N2C=CC2=NC(=O)NC21N3c1cc(Br)ccc14

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (1R,9R,19S,21R)-5-bromo-21-chloro-20,20-dimethyl-2,12,16,18-tetrazahexacyclo[10.10.0.01,9.02,19.03,8.015,19]docosa-3(8),4,6,13,15-pentaene-11,17-dione is a natural product found in Securiflustra securifrons with data available.
Molecule SMILES: O=C1CC(c2ccc(O)cc2)Oc2c(O)c(O)cc(O)c21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 8-Hydroxynaringenin is a natural product found in Dalbergia odorifera and Scutellaria baicalensis with data available.
Molecule SMILES: COC(=O)c1[nH]c2ccc(Br)cc2c1NC(=O)CN1CCN(C2CCCCC2)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 5-bromo-3-[[2-(4-cyclohexyl-1-piperazinyl)-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl ester is an indolyl carboxylic acid.
Molecule SMILES: CC1CCCC=CC=CC(O)CC(O)CC=CC=CC(OC(=O)CC(=O)O)CC=CC=CC(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 3-[[(5E,8S,14S,16R,17E,19E,24R)-14,16-dihydroxy-24-methyl-2-oxo-1-oxacyclotetracosa-3,5,9,11,17,19-hexaen-8-yl]oxy]-3-oxopropanoic acid is a natural product found in Bacillus velezensis with data available.
Molecule SMILES: C=C1C(O)CC2CC1C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (1r,3s,5r)-6,6-Dimethyl-2-methylidenebicyclo[3.1.1]heptan-3-ol is a natural product found in Xylopia aromatica, Xylopia sericea, and other organisms with data available.
Molecule SMILES: C=C(C)C1CCC2(NCCN3CCS(=O)(=O)CC3)CCC3(C)C(CCC4C5(C)CC=C(C6=CCC(CF)(C(=O)O)CC6)C(C)(C)C5CCC43C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: GSK3640254 is an investigational drug that is being studied to treat HIV infection.
Molecule SMILES: C=C(C)C1CCC2(NCCN3CCS(=O)(=O)CC3)CCC3(C)C(CCC4C5(C)CC=C(C6=CCC(CF)(C(=O)O)CC6)C(C)(C)C5CCC43C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: GSK3640254 belongs to a group of HIV drugs called maturation inhibitors. Maturation inhibitors work during the last stage of the HIV life cycle and interfere with the formation of mature, infectious virus. Specifically, maturation inhibitors block a long HIV protein chain called Gag from being broken up into smaller parts that are needed to create mature virus. This prevents HIV from multiplying, and can reduce the amount of HIV in the body.
Molecule SMILES: C=CCc1cc(C)ccc1OCC(O)CN1CCN(c2ccccc2)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 1-(4-methyl-2-prop-2-enylphenoxy)-3-(4-phenyl-1-piperazinyl)-2-propanol is a member of piperazines.