IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=C1C(=O)OC2C1CC(O)C(=C)C1CC(OC3OC(CO)C(O)C(O)C3O)C(=C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (3aS,5R,6aR,8R,9aR,9bS)-5-hydroxy-3,6,9-trimethylidene-8-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one is a natural product found in Launaea arborescens with data available.
Molecule SMILES: O=C1CC(c2ccc(O)cc2)Oc2ccccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 4'-hydroxyflavanone is a monohydroxyflavanone and a member of 4'-hydroxyflavanones.
Molecule SMILES: O=C1CC(c2ccc(O)cc2)Oc2ccccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 4'-Hydroxyflavanone is a natural product found in Dianthus caryophyllus with data available.
Molecule SMILES: CCCCCC1CCCCCCCCCC(=O)OC2C(OC3OC(C)C(OC(=O)C(C)C(C)O)C(O)C3O)C(C)OC(OC3C(OC(COC(=O)C(C)C(C)O)C(O)C3O)OC3C(O1)OC(C)C(O)C3O)C2OC(=O)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [30-[3,4-Dihydroxy-5-(3-hydroxy-2-methylbutanoyl)oxy-6-methyloxan-2-yl]oxy-4,5,11,12-tetrahydroxy-13,31-dimethyl-33-(2-methylpropanoyloxy)-27-oxo-17-pentyl-2,7,9,14,16,28,32-heptaoxatetracyclo[27.3.1.03,8.010,15]tritriacontan-6-yl]methyl 3-hydroxy-2-methylbutanoate is a natural product found in Ipomoea stans with data available.
Molecule SMILES: C=C1CCC2C(C)(C)CCCC2(C)C1CCC(C)=CC=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (E)-5-[(1R,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-2-enal is a natural product found in Pinus pumila with data available.
Molecule SMILES: CCCCCCCCC(CCC(=O)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-Octylpentanedioic acid is a natural product found in Gongronella butleri with data available.
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)COC1OC(Oc2cc(O)c3c(=O)cc(-c4ccc(O)cc4)oc3c2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 5-hydroxy-2-(4-hydroxyphenyl)-7-[(2R,3R,4S,5S,6S)-3,4,5-trihydroxy-6-[(Z)-4-(4-hydroxyphenyl)-2-oxobut-3-enoxy]oxan-2-yl]oxychromen-4-one is a natural product found in Stachys byzantina with data available.
Molecule SMILES: CC1CCC2C1C1C(CCC2(C)O)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: epi-Globulol is a natural product found in Bazzania trilobata, Melaleuca alternifolia, and other organisms with data available.
Molecule SMILES: CC1=CCc2ccc([nH]2)C2=NC(C=C3C(=C(C)CCCO)COC3CC(C)C)C(COC(=O)C(CC(C)C)CC(=O)OC3C1OC(=O)C3(C)CO)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (7E,9R,12R,13S,17S,21S,22S)-12-(hydroxymethyl)-22-[(Z)-[(2S,4Z)-4-(5-hydroxypentan-2-ylidene)-2-(2-methylpropyl)oxolan-3-ylidene]methyl]-8,12-dimethyl-17-(2-methylpropyl)-10,14,19,24-tetraoxa-23,25-diazatetracyclo[19.2.1.12,5.09,13]pentacosa-1(23),2,4,7-tetraene-11,15,18-trione is a natural product found in Sorangium cellulosum with data available.
Molecule SMILES: CC=C(C)C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Ingenol Mebutate is a selective small-molecule activator of protein kinase C (PKC) isolated from the plant Euphorbia peplus with potential antineoplastic activity. Ingenol mebutate activates various protein kinase C (PKC) isoforms, thereby inducing apoptosis in some tumor cells, including myeloid leukemia cells, melanoma cells, and basal cell carcinoma cells. The PKC family consists of signaling isoenzymes that regulate many cell processes including proliferation, differentiation, and apoptosis.
Molecule SMILES: C=C1OC(=O)C(CCCCCCC=CCC=CCC=CCCO)=C1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 3-(16-Hydroxyhexadeca-7,10,13-trienyl)-4-methoxy-5-methylidenefuran-2-one is a natural product found in Artabotrys hexapetalus with data available.
Molecule SMILES: O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2ccc(Cl)cc2)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Ralinepag has been used in trials studying the treatment of Pulmonary Arterial Hypertension.
Molecule SMILES: C#Cc1c[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’s most widely-used oncology agents.  5-FU is widely used in the U.S. and is often first or second line therapy for a variety of cancers including colorectal, breast, gastric, head and neck, ovarian and basal cell cancer of the skin. Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making it orally available. Eniluracil has received Orphan Drug status from the FDA for the treatment of hepatocellular cancer in combination with fluoropyrimidines (including 5-FU).
Molecule SMILES: C#Cc1c[nH]c(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Eniluracil is an orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU.
Molecule SMILES: CCCCC=CCCCCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Myristoleic acid is a tetradecenoic acid in which the double bond is at the 9-10 position and has Z configuration. Myristoleic acid has been isolated from Serenoa repens and has cytotoxic and apoptosis-inducing effects. It has a role as an apoptosis inducer, a plant metabolite and an EC 3.1.1.1 (carboxylesterase) inhibitor. It is a tetradecenoic acid and a long-chain fatty acid. It is a conjugate acid of a myristoleate.
Molecule SMILES: CCCCC=CCCCCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Myristoleic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
Molecule SMILES: CCCCC=CCCCCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Myristoleic acid is a natural product found in Gladiolus italicus, Erucaria microcarpa, and other organisms with data available.
Molecule SMILES: COC(COC(C)=O)C(OC)C(O)C(CO)OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: [(2R,3R,4R,5S)-5-acetyloxy-4,6-dihydroxy-2,3-dimethoxyhexyl] acetate is a natural product found in Grifola frondosa with data available.
Molecule SMILES: CC1(C)OC(C)(C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C5C(C)(C)C(OC6OCC(O)C(O)C6OC6OC(CO)C(O)C(O)C6O)CCC56CC46CCC23C)CCC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (2R,3R,4S,5S,6R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-6-[(2S,3R,4S,5R)-4,5-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-14-hydroxy-15-[(2R,5S)-5-hydroxy-2,6,6-trimethyloxan-2-yl]-7,7,12,16-tetramethyl-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a natural product found in Astragalus tragacantha with data available.
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)OC1CC2(O)CC(OC2=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3-p-Coumaroyl-1,5-quinolactone is a cinnamate ester.
Molecule SMILES: COc1cc(-c2oc3cc(OC4OC(COC5OC(CO)C(O)C(O)C5O)C(O)C(O)C4O)cc(O)c3c(=O)c2OC2OC(CO)C(O)C(O)C2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one is a natural product found in Nerisyrenia camporum and Nerisyrenia linearifolia with data available.
Molecule SMILES: [C-]#[N+]C(C)(CCC=C(C)C)C1CC=C(C)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (4R)-4-[(2S)-2-isocyano-6-methylhept-5-en-2-yl]-1-methylcyclohexene is a natural product found in Acanthella cavernosa with data available.
Molecule SMILES: CCCCCCCCCC(=O)CC(=O)CCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Henicosane-10,12-dione is a natural product found in Microcystis aeruginosa with data available.
Molecule SMILES: C=C(C)C1CCC2=CC(CCC(C)(O)C(=O)C=C(C)C(=O)C1)OC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Rubifol is a natural product found in Gersemia rubiformis with data available.
Molecule SMILES: OC1c2c(F)cccc2N=C2CCCCN21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 1-fluoro-7,8,9,11-tetrahydro-6H-pyrido[2,1-b]quinazolin-11-ol is a member of quinazolines.
Molecule SMILES: O=C(NCCC1CCC(NC(=O)C2CCCCC2)C(CO)O1)c1ccc(F)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: N-[2-[(2S,5S,6S)-5-[[cyclohexyl(oxo)methyl]amino]-6-(hydroxymethyl)-2-oxanyl]ethyl]-4-fluorobenzamide is a C-glycosyl compound.
Molecule SMILES: COC(=O)C1(C)CCC2(C(=O)OC3OC(CO)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6O)C(C)(CO)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3-O-(3-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)phytolaccagenic acid 28-O-beta-D-glucopyranosyl is a natural product found in Diploclisia glaucescens with data available.
Molecule SMILES: CCC(O)C(C)(O)C=CCC(C)=CC(O)C(=O)NCCC(O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: N-(3,4-dihydroxybutyl)-2,8,9-trihydroxy-4,8-dimethylundeca-3,6-dienamide is a natural product found in Streptomyces maoxianensis with data available.
Molecule SMILES: COC(C)C(C=CC=Cc1cccc(O)c1C(=O)Oc1ccccc1O)C(=O)C(C)=CC1OC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (2-hydroxyphenyl) 2-hydroxy-6-[(1E,3E,5S,7E)-5-[(1S)-1-methoxyethyl]-7-methyl-8-[(2R,3R)-3-methyloxiran-2-yl]-6-oxoocta-1,3,7-trienyl]benzoate is a natural product found in Streptomyces with data available.
Molecule SMILES: Cc1cc(O)c2c3c(ncc2c1)C(=O)c1c(O)cccc1C3=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Benzo[b]phenanthridine-7,12-dione, 1,8-dihydroxy-3-methyl- is a natural product found in Streptomyces and Micromonospora rosaria with data available.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCC=CCC=CCC=CCC)OC(=O)CCCCCCCC=CCC=CCC=CCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Propane-1,2,3-triyl trioctadeca-9,12,15-trienoate is a natural product found in Euphorbia petiolata and Inezia integrifolia with data available.
Molecule SMILES: CCC(C)CCCCCCCCCCCCC(O)C(COC1OC(C(O)CO)C(O)C1O)NC(=O)C(O)CCCCCCCCCCCC(C)CC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2R,14R)-N-[(2S,3S,16S)-1-[(2R,3R,4R,5S)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxy-16-methyloctadecan-2-yl]-2-hydroxy-14-methylhexadecanamide is a natural product found in Ectyoplasia ferox with data available.
Molecule SMILES: CC(C=CC=CC(=O)O)C1OC2(CC(O)C(C)C(C)O2)C(C)C(O)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Pteridic acid E is a natural product found in Streptomyces with data available.
Molecule SMILES: CC12CC(c3ccoc3)OC(=O)C1CCC1(C)C2C2C=CC1(OC1OC(CO)C(O)C(O)C1O)C(=O)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (1R,2S,3S,5S,8R,11R,12R)-5-(furan-3-yl)-3,11-dimethyl-12-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione is a natural product found in Penianthus zenkeri and Tinospora cordifolia with data available.
Molecule SMILES: CC=CCC=CCC=CC=CC=CC=CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Thailandene C is a natural product found in Burkholderia thailandensis with data available.
Molecule SMILES: COc1ccc(C(=O)OC2CC(C)=C(C=O)C2CC=O)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(1S,2R)-3-formyl-4-methyl-2-(2-oxoethyl)cyclopent-3-en-1-yl] 3,4-dimethoxybenzoate is a natural product found in Handroanthus impetiginosus with data available.
Molecule SMILES: COc1cc(OC)c(Cl)c(-c2cc(=O)c3ccc4occc4c3o2)c1Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-(2,6-Dichloro-3,5-dimethoxyphenyl)furo[2,3-h]chromen-4-one is a natural product found in Pongamia pinnata with data available.
Molecule SMILES: CC1(C)C(=O)C2CC34OC2(O)C2(COC(=O)CC12)C3CCC1(C)C(c2ccoc2)OC(=O)CC14

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (1S,2R,6R,7R,10R,11S,16S,20S)-6-(furan-3-yl)-20-hydroxy-7,17,17-trimethyl-5,13,21-trioxahexacyclo[17.2.1.01,10.02,7.011,16.011,20]docosane-4,14,18-trione is a natural product found in Khaya senegalensis with data available.
Molecule SMILES: COC(=O)C(O)CC(OC)c1c(O)c(OC)c(C)c2c1Oc1c(C)cc(O)cc1OC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Curdepsidone C is a natural product found in Curvularia with data available.
Molecule SMILES: CC12CCC3C(CCC4=CC(=O)CC43C)C1CCC(=O)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: D-Homo-A-nor-17a-oxaandrost-3(5)-ene-2,17-dione is a steroid lactone.
Molecule SMILES: COC1C(=O)OC(C)C(C)C=C(C)CC(C)C(=O)NC(C)C(=O)N(C)C(Cc2c(Cl)[nH]c3ccccc23)C(=O)NC1c1ccc(OP(=O)(O)O)c(Cl)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Chrondramide 10 is a natural product found in Chondromyces with data available.
Molecule SMILES: CC1C(=O)CC2CC1C2(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Bicyclo[3.1.1]Heptan-3-One, 2,6,6-Trimethyl-, [1S-(1a,2ss,5a)]- is a natural product found in Xylopia aromatica, Aloysia gratissima, and other organisms with data available.
Molecule SMILES: CC1=C(CCC(=O)[O-])c2cc3[n-]c(cc4nc(cc5[n-]c(cc1n2)c(C)c5C)C(C)C4(C)C)c(C)c3CCC(=O)[O-].[Fe]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Iron methylchlorin(2-) is a dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxy groups of iron methylchlorin. Major species at pH 7.3. It is a conjugate base of an iron methylchlorin.
Molecule SMILES: O=C(C=Cc1ccc(O)c(O)c1)OC1C(CO)OC(OCC(O)c2ccc(O)c(O)c2)C(O)C1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Hellicoside is a hydroxycinnamic acid.
Molecule SMILES: O=C(C=Cc1ccc(O)c(O)c1)OC1C(CO)OC(OCC(O)c2ccc(O)c(O)c2)C(O)C1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Hellicoside is a natural product found in Plantago asiatica, Plantago major, and Plantago depressa with data available.
Molecule SMILES: CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(Cl)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Pimecrolimus is a 33-epi-chloro-derivative of the ascomycin macrolactam with immunosuppressant property. Pimecrolimus binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineurin. Via dephosphorylation, calcineurin is the enzyme responsible for activating nuclear factor of activated T-cells (NF-AT), a T cell transcriptional regulatory factor. As a consequence, the synthesis and release of Th1- (T helper 1) and Th2- (T helper 2) type cytokines, and other inflammatory mediators from T-cells and mast cells are blocked and the expression of signals essential for the activation of inflammatory T-lymphocytes is inhibited. However, pimecrolimus mode of action is cell-selective and does not affect Langerhans' cells/dendritic cells and primary fibroblasts.
Molecule SMILES: COc1cc(C=CC(=O)OC2CC(OC(=O)CCc3ccc(O)c(O)c3)(C(=O)O)CC(OC(=O)CCc3ccc(O)c(O)c3)C2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Feruloylpodospermic acid A is a natural product found in Takhtajaniantha pseudodivaricata, Scorzonera virgata, and Gelasia aucheriana with data available.
Molecule SMILES: CC(O)CCC(C)CC(C)CCC(O)CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3,11-Dihydroxy-6,8-dimethyldodecanoic acid is a natural product found in Penicillium decumbens with data available.
Molecule SMILES: CC=C(C)C(=O)OC1C(OC(=O)C(C)=CC)C2(CO)C(CC1(C)C)C1=CCC3C4(C)CCC(OC5OC(C(=O)O)C(O)C(OC6OCC(O)C(O)C6O)C5O)C(C)(C(=O)OC)C4CCC3(C)C1(C)C(O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: TR-saponin A is a natural product found in Camellia sinensis with data available.
Molecule SMILES: Cc1cnc(NC(=O)C2=C(O)c3c(O)cccc3S(=O)(=O)N2C)s1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 5'-Hydroxy meloxicam is a benzothiazine.
Molecule SMILES: CCCC(=O)OC1C(C)OC(OC2C(C)OC(OC3C(CC=O)CC(C)C(=O)C=CC=CCC(C)OC(=O)CC(OC(=O)CC)C3OC)C(O)C2N(C)C)CC1(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [6-[4-(dimethylamino)-5-hydroxy-6-[[(11E,13E)-5-methoxy-9,16-dimethyl-2,10-dioxo-7-(2-oxoethyl)-4-propanoyloxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] butanoate is a natural product found in Streptomyces mycarofaciens with data available.