IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=C(C(=O)OC1C(=C)C(O)C2C(OC(=O)C(C)=CC)C(C)CC2(O)C(=O)C(C)(O)C=CC(C)(C)C(OC(C)=O)C1OC(C)=O)C(C)OO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1S,2S,3aR,5R,6E,9S,10S,11S,13R,13aS)-9,10-diacetyloxy-3a,5,13-trihydroxy-2,5,8,8-tetramethyl-1-[(Z)-2-methylbut-2-enoyl]oxy-12-methylidene-4-oxo-1,2,3,9,10,11,13,13a-octahydrocyclopenta[12]annulen-11-yl] (3S)-3-hydroperoxy-2-methylidenebutanoate is a natural product found in Euphorbia amygdaloides with data available.
Molecule SMILES: CC(=O)O.CCC(C)C(NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(N)=O)C(C)CC)C(C)C)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Sermorelin Acetate is the acetate salt form of sermorelin, a synthetic, amidated 29-amino acid peptide that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH). Sermorelin acetate directly stimulates the pituitary gland, resulting in release of growth hormone leading to increased plasma growth hormone, which is responsible for many biological processes and counteracts growth hormone deficiency.
Molecule SMILES: CCCCC(=O)Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Valeryl chloride appears as a colorless fuming liquid with a pungent odor. Fumes irritate the eyes and mucous membranes. Corrosive.
Molecule SMILES: CC(O)(CO)C1CCC2(C)CCCC(C)(O)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Teucdiol F is a natural product found in Termitomyces albuminosus with data available.
Molecule SMILES: CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 1-[(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl]-2-hexadecanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 38:6 in which the acyl groups specified at positions 1 and 2 are (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl and hexadecanoyl respectively. It is functionally related to a hexadecanoic acid and an all-cis-docosa-4,7,10,13,16,19-hexaenoic acid.
Molecule SMILES: NC(=O)c1c(NC(=O)c2ccccc2)sc2c1CCc1ccccc1-2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2-benzamido-4,5-dihydrobenzo[g][1]benzothiole-3-carboxamide is an organosulfur heterocyclic compound and an organic heterotricyclic compound.
Molecule SMILES: CC1=CC(=O)C2(C)C1=CC(=O)C1(C)C3C(=O)OC(C3C)C(O)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Laurycolactone B is a natural product found in Eurycoma longifolia with data available.
Molecule SMILES: C=C1CCC23C(=O)OC4OC(c5ccoc5)CC14C2CCC=C3C(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: methyl (1R,4S,6R,8R,9S)-6-(furan-3-yl)-16-methylidene-2-oxo-3,5-dioxatetracyclo[6.5.3.01,9.04,8]hexadec-12-ene-13-carboxylate is a natural product found in Croton verreauxii with data available.
Molecule SMILES: COc1cc(C2OCC3C(c4ccc5c(c4)OCO5)OCC23)cc(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (+)-Aschantin is a natural product found in Artemisia nitrosa, Artemisia schischkinii, and other organisms with data available.
Molecule SMILES: O=C([O-])CC(=O)C=C(Br)C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2-bromomaleylacetate is an oxo dicarboxylate and a bromocarboxylic acid anion. It is functionally related to a hex-2-enedioate and a maleylacetate.
Molecule SMILES: CC(C)C1=CC2=C(C(=O)CC2C)C(C)(O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Nardoguaianone F is a natural product found in Nardostachys jatamansi with data available.
Molecule SMILES: Nc1nc2ncc(CN(C=O)c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)nc2c(=O)[nH]1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 10-Formylfolic acid is a natural product found in Capsicum annuum var. annuum with data available.
Molecule SMILES: COC(=O)CC=C(C)CCc1c(O)cc2c(c1O)CN(CCO)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: methyl 6-[4,6-dihydroxy-2-(2-hydroxyethyl)-1-oxo-3H-isoindol-5-yl]-4-methylhex-3-enoate is a natural product found in Hericium erinaceus with data available.
Molecule SMILES: COc1cc(C2c3c(cc(OC)c(O)c3OC)C=C3C(=O)OCC4OC(CO)(OC5OC(CO)C(O)C(O)C5O)C(OC(=O)C32)C4O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (1S,4R,5R,17R,19S,20R)-8,20-dihydroxy-5-(4-hydroxy-3-methoxyphenyl)-19-(hydroxymethyl)-7,9-dimethoxy-19-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,15,18-trioxatetracyclo[15.2.1.04,13.06,11]icosa-6,8,10,12-tetraene-3,14-dione is a natural product found in Trigonotis peduncularis with data available.
Molecule SMILES: CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-formyl-L-methionyl-L-leucyl-L-phenylalanine is a tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor. It is functionally related to a N-formyl-L-methionine, a L-leucine and a L-phenylalanine. It is a conjugate acid of a N-formyl-L-methionyl-L-leucyl-L-phenylalaninate.
Molecule SMILES: C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)C=CC(O)C2(C(=O)OCCCC)CC2)CC(O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: ZK 159222 is a vitamin D.
Molecule SMILES: CC(=O)OCC1=C2C(OC(C)=O)CC(C)C(=O)CCC3(C)OC3C2OC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(1S,2R,4R,8S,10S)-10-acetyloxy-4,8-dimethyl-7,13-dioxo-3,14-dioxatricyclo[9.3.0.02,4]tetradec-11-en-12-yl]methyl acetate is a natural product found in Quechualia fulta with data available.
Molecule SMILES: CC(=O)OC1C2CC3(O)OCC45C(O)CCC6(C)C(O)C(OC(C)=O)C(C2(C)C)(C34C)C165

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Taxpropellane is a natural product found in Taxus canadensis with data available.
Molecule SMILES: CC=C1C(OC2OC(CO)C(O)C(O)C2O)OC=C(C(=O)OC)C1CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Jaspolyside is a natural product found in Jasminum polyanthum with data available.
Molecule SMILES: CC(=O)NC1C(OP(=O)([O-])OP(=O)([O-])OCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)OC(CO)C(O)C1OC1OC(C)C(O)C(OC2OC(COC3OC(C(O)CO)C(O)C3O)C(O)C(O)C2O)C1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Galactofuranosyl-glucosyl-O-acetyl-rhamanosyl-N-acetylglucosamyl-undecaprenyl diphosphate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: CCCCCCCCCCCCCCCCCC(=O)N1CCCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-(1-pyrrolidinyl)-1-octadecanone is a member of pyrrolidines.
Molecule SMILES: CCCCCCCCCCCCCCCCCC(=O)N1CCCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Pyrrolidine, 1-stearoyl- is a natural product found in Piper amalago with data available.
Molecule SMILES: CC=C(C)C(=O)OC1CC2C3(C)CCC(OC4CC(OC)C(OC5CC(OC)C(OC6CC(OC)C(OC7CC(OC)C(OC8OC(C)C(OC9OC(CO)C(O)C(O)C9O)C(OC)C8O)C(C)O7)C(C)O6)C(C)O5)C(C)O4)CC3=CCC2(O)C2(O)CCC(O)(C(C)O)C12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Marstomentoside K is a natural product found in Marsdenia tomentosa with data available.
Molecule SMILES: CC1C(=CCO)C=CC2C1CCC1(O)C2(C)CCC(OC(=O)C(CCO)c2c(O)cc3c(c2O)C(=O)c2c(O)cc(O)cc2C3=O)C1(C)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Arbusculic acid B is a natural product found in Calcarisporium arbuscula with data available.
Molecule SMILES: CCN1CC2(COC)CCC(O)C34C5CC6C(OC)CC(O)(C5C6OC(C)=O)C(O)(C(OC)C23)C14

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: [(1S,2R,3R,4R,5R,6S,8R,9S,10S,13S,16R,17R,18R)-11-ethyl-8,9,16-trihydroxy-6,18-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] acetate is a natural product found in Delphinium caeruleum with data available.
Molecule SMILES: CC12CCC3C(CC3(C)C)C(O)(CC(O)C1)C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Micaryolane A is a natural product found in Streptomyces with data available.
Molecule SMILES: CC12C(O)CC3C(CCC4CC5OC6OC(CO)CC(O)C6(O)OC5CC43CO)C1(O)CCC2C1=CC(=O)OC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-[(1S,3S,5S,7R,9S,10R,12S,14S,15S,17R,18S,19R,22S,23R)-9,10,17,22-tetrahydroxy-7,14-bis(hydroxymethyl)-18-methyl-4,6,11-trioxahexacyclo[12.11.0.03,12.05,10.015,23.018,22]pentacosan-19-yl]-2H-furan-5-one is a natural product found in Pergularia tomentosa with data available.
Molecule SMILES: CC(C)CCNc1ccc(CC(N)=O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Benzeneacetamide, 4-((3-methylbutyl)amino)- is a natural product found in Bongardia chrysogonum with data available.
Molecule SMILES: CC(=O)OC1CC2(C)C3CCC4(C)C(CCC4C(C)C4OC4C(C)C(C)C)C3=CCC2C(OS(=O)(=O)O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Ergost-7-ene-2,3,4-triol, 22,23-epoxy-, 2-acetate 4-(hydrogen sulfate), (2alpha,3beta,4alpha,5alpha,22S,23S)- is a natural product found in Acanthodendrilla with data available.
Molecule SMILES: COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C2C(C)(O)CC(O)C12O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 6beta-Hydroxyipolamiide is a natural product found in Lamium amplexicaule, Stachytarpheta mutabilis, and Phlomis rigida with data available.
Molecule SMILES: Cc1cn2c(=O)c3ncn(C4OC(CO)C(O)C4O)c3n(C)c2n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Wyosin is a nucleobase-containing molecular entity and a carbohydrate derivative.
Molecule SMILES: Cc1cn2c(=O)c3ncn(C4OC(CO)C(O)C4O)c3n(C)c2n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Wyosine is a natural product found in Bulgaria with data available.
Molecule SMILES: C=C1C(=O)OC2C1CC(O)C(C)=C1CC=C(COC3OC(COC(=O)Cc4ccc(O)cc4)C(O)C(O)C3O)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3-Methylene-6-methyl-5beta-hydroxy-9-[[6-O-(p-hydroxyphenylacetyl)-beta-D-glucopyranosyloxy]methyl]-3abeta,4,5,7,9abeta,9balpha-hexahydroazuleno[4,5-b]furan-2(3H)-one is a natural product found in Crepidiastrum lanceolatum with data available.
Molecule SMILES: C=C1C(C)C2C(C)NC(=O)C23C(=O)CC(O)C2(C)OC2C(C)CC=CC3C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Alachalasin D is a natural product found in Podospora vesticola and Schizothecium vesticola with data available.
Molecule SMILES: COc1cc(C=CC(=O)OCC2(O)COC(OC3C(Oc4cc(O)c5c(=O)cc(-c6ccc(O)cc6)oc5c4)OC(CO)C(O)C3O)C2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2-(4-Hydroxyphenyl)-5-hydroxy-7-[2-O-[5-O-[(E)-3-methoxy-4-hydroxycinnamoyl]-D-apio-beta-D-furanosyl]-beta-D-glucopyranosyloxy]-4H-1-benzopyran-4-one is a natural product found in Apium graveolens with data available.
Molecule SMILES: C=C(C)C(O)COc1ccc2c(OC)c3ccoc3nc2c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (2S)-1-(4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbut-3-en-2-ol is a natural product found in Haplophyllum acutifolium and Haplophyllum obtusifolium with data available.
Molecule SMILES: COc1cc(O)c(O)c(CC=C(C)C)c1-c1coc2cc(O)cc(O)c2c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Piscidone is a natural product found in Piscidia piscipula with data available.
Molecule SMILES: CC(=CCCC1(C)C=Cc2cc(O)c(C)cc2O1)Cc1cc(C)co1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2R)-2,7-dimethyl-2-[4-methyl-5-(4-methylfuran-2-yl)pent-3-enyl]chromen-6-ol is a natural product found in Sinularia capillosa with data available.
Molecule SMILES: CCC1(O)CC(OC2CC(N(C)C)C(OC3CC(O)C(OC4OC(C)C(=O)C=C4N)C(C)O3)C(C)O2)c2c(cc3c(c2O)C(=O)c2c(O)ccc(O)c2C3=O)C1C(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Rudolfomycin is a natural product found in Streptomyces with data available.
Molecule SMILES: Oc1ccc2c3c1OC1C(O)C=CC4C(C2)NCCC341

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Normorphine is a morphinane alkaloid.
Molecule SMILES: CC(=O)OC1CC(C)C2(C)CC3CCC(C)(OC3(C)C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1S,2S,3R,5R,6R,8R)-1,5,6,9,9-pentamethyl-10-oxatricyclo[6.2.2.02,6]dodecan-3-yl] acetate is a natural product found in Valeriana officinalis with data available.
Molecule SMILES: O=C1CC(c2ccc(O)c(O)c2)c2c(cc(O)c3c2OC(c2ccc(O)c(O)c2)C(O)C3c2c(O)cc(O)c3c2OC(c2ccc(O)c(O)c2)C(O)C3)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (4S)-4beta,6alpha-Bis(3,4-dihydroxyphenyl)-7alpha,9-dihydroxy-8beta-[(2R)-2alpha-(3,4-dihydroxyphenyl)-3beta,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-8-yl]-2,3,4,6,7,8-hexahydro-1,5-dioxaphenanthrene-2-one is a natural product found in Kandelia candel with data available.
Molecule SMILES: COC=C1C(=O)c2c(O)cc(OC)cc2C2OC(C)(OC)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Scytalol C is a natural product found in Scytalidium with data available.
Molecule SMILES: CC(C)(O)C1Cc2c(ccc(C(=O)C=Cc3ccc(O)cc3)c2O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Bakuchalcone is a natural product found in Cullen corylifolium with data available.
Molecule SMILES: COc1cc(C=CC(=O)OCC2OC(OCC3C(Cc4ccc(O)c(OC)c4)COC3c3cc(OC)c(O)c(OC)c3)C(O)C(O)C2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2S)-2alpha-(3,5-Dimethoxy-4-hydroxyphenyl)-3beta-[6-O-[(Z)-3-(3-methoxy-4-hydroxyphenyl)acryloyl]-beta-D-glucopyranosyloxymethyl]-4beta-(3-methoxy-4-hydroxybenzyl)tetrahydrofuran is a natural product found in Asclepias curassavica with data available.
Molecule SMILES: Cn1c(Nc2ccc(C(F)(F)F)cc2)nc2cc(Oc3ccnc(-c4ncc(C(F)(F)F)[nH]4)c3)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-2-benzimidazolamine is an aromatic ether.
Molecule SMILES: Cn1c(Nc2ccc(C(F)(F)F)cc2)nc2cc(Oc3ccnc(-c4ncc(C(F)(F)F)[nH]4)c3)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: B-Raf/VEGFR-2 Inhibitor RAF265 is an orally bioavailable small molecule with potential antineoplastic activity. CHIR-265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR-2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras/Raf/MEK/ERK signaling pathway and are frequently upregulated in neoplasms.
Molecule SMILES: CC(C)N(CC1OC(n2cnc3c(N)ncnc32)C(O)C1O)C1CC(CCc2nc3ccc(C(C)(C)C)cc3[nH]2)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Molecule SMILES: CC(C)N(CC1OC(n2cnc3c(N)ncnc32)C(O)C1O)C1CC(CCc2nc3ccc(C(C)(C)C)cc3[nH]2)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Pinometostat is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. Upon intravenous administration, pinometostat specifically blocks the activity of the histone lysine-methyltransferase DOT1L, thereby inhibiting the methylation of nucleosomal histone H3 on lysine 79 (H3K79) that is bound to the mixed lineage leukemia (MLL) fusion protein which targets genes and blocks the expression of leukemogenic genes. This eventually leads to an induction of apoptosis in the leukemic cells bearing the MLL gene translocations. DOT1L, a non-SET domain-containing histone methyltransferase, specifically methylates H3K79 and plays a key role in normal cell differentiation and in the development of leukemia with MLL gene rearrangement on chromosome 11 and promotes the expression of leukemia-causing genes.
Molecule SMILES: CCCCCc1cc(C)c(CCCCCCCCCCC(=O)OC(CO)COC(=O)CCCCCCCCCCCCc2oc(CCCCC)c(C)c2C)o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: DG(13D5/11M5/0:0) is a heterocyclic fatty acid.
Molecule SMILES: COc1cc(OC)c2c(c1CC=C(C)C)OC(c1ccccc1)CC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Candidone is a member of flavanones.
Molecule SMILES: COc1cc(OC)c2c(c1CC=C(C)C)OC(c1ccccc1)CC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Candidone is a natural product found in Lonchocarpus costaricensis, Pongamia pinnata, and Tephrosia candida with data available.