IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COc1cc(-c2cc(=O)c3c(O)cc(OC4OC(COC(=O)C=Cc5ccc(O)cc5)C(O)C(OC(=O)C=Cc5ccc(O)cc5)C4O)cc3o2)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(2R,3R,4S,5S,6S)-3,5-dihydroxy-6-[5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxochromen-7-yl]oxy-4-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate is a natural product found in Marrubium velutinum with data available.
Molecule SMILES: COc1cc(C(=O)C(CO)c2ccc(O)c(OC)c2)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Evofolin B is a natural product found in Sida acuta, Microtropis japonica, and other organisms with data available.
Molecule SMILES: C=C1C(=O)OC2C3=C(C)C(O)CC(O)C3(C)CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Armefolin is a natural product found in Tanacetum parthenium, Chamaemelum fuscatum, and Artemisia ludoviciana with data available.
Molecule SMILES: O=C(O)C1=NC(C(=O)O)CC(C=CN2c3cc(O)c(OC4OC(CO)C(O)C(O)C4OC4OC(C(=O)O)C(O)C(O)C4O)cc3CC2C(=O)O)=C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (2S)-4-[(E)-2-[(2S)-2-carboxy-5-[(2S,3R,4S,5S,6R)-3-[(2R,4S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxy-2,3-dihydroindol-1-yl]ethenyl]-2,3-dihydropyridine-2,6-dicarboxylic acid is a natural product found in Amaranthus hypochondriacus and Amaranthus hybridus with data available.
Molecule SMILES: CC(=O)OCC12CC(OC(=O)CC(C)C)C(C)=CC1OC1C(OC(C)=O)C(OC(C)=O)C2(C)C12CO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Acetyl T-2 is a natural product found in Fusarium poae, Fusarium sporotrichioides, and Fusarium graminearum with data available.
Molecule SMILES: CC=Cc1cc(OC)c(OC2OC(CO)C(O)C(O)C2O)cc1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-methoxy-2-prop-1-enyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenoxy]oxane-3,4,5-triol is a natural product found in Lespedeza juncea with data available.
Molecule SMILES: CC1(C)C2CCC(COC3OC(COC4OCC(O)C(O)C4O)C(O)C(O)C3O)C1C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Sachaloside I is a natural product found in Rhodiola rosea and Rhodiola sachalinensis with data available.
Molecule SMILES: CC1CCCCOC(CN(C)Cc2ccc(C(F)(F)F)cc2)C(C)CN(C(C)CO)C(=O)c2cc(NC(=O)c3ccncc3)ccc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: N-[(3R,9S,10R)-12-[(2R)-1-hydroxypropan-2-yl]-3,10-dimethyl-9-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-13-oxo-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]-4-pyridinecarboxamide is an azamacrocycle and a lactam.
Molecule SMILES: O=C1N=C2NC(=O)NC(=O)C2N1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 5,7-dihydro-1H-purine-2,6,8(9H)-trione is a uric acid. It is a tautomer of a 9H-purine-2,6,8-triol, a 1H-purine-2,6,8-triol, a 7H-purine-2,6,8-triol, a 2,6-dihydroxy-7,9-dihydro-8H-purin-8-one and a 7,9-dihydro-1H-purine-2,6,8(3H)-trione.
Molecule SMILES: CC(C)CCNC(=S)Nc1ccc(Br)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1-(4-bromophenyl)-3-(3-methylbutyl)thiourea is a member of thioureas.
Molecule SMILES: Cc1ccc(-c2ccc3n2CCC3)o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 5-(5-Methyl-2-furyl)-2,3-dihydro-1H-pyrrolizine is a member of pyrrolizines.
Molecule SMILES: C=C1C(=O)OC2CC(C)C3CCC4(C)OC34CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 4,5-Epoxy-11(13)-guaien-12,8-olide is a natural product found in Carpesium cernuum with data available.
Molecule SMILES: COc1cc(-c2oc3cc(O)cc(O)c3c(=O)c2OC2OC(C(=O)O)C(O)C(O)C2O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 6-{[5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid is a member of flavonoids and a glucosiduronic acid.
Molecule SMILES: CC(C)CNC(=O)C1C(c2ccc3c(c2)OCO3)C=CC2CCCCC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1beta,2alpha,4abeta,8abeta)-2-(1,3-Benzodioxol-5-yl)-1,2,4a,5,6,7,8,8a-octahydro-N-isobutyl-1-naphthalenecarboxamide is a natural product found in Piper guineense with data available.
Molecule SMILES: CC12CCC3OC(=O)C=C3C1CCC13CC(CCC12O)C(O)(CO)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (1S,4R,9R,12R,13S,16S,17R)-13,17-dihydroxy-17-(hydroxymethyl)-12-methyl-8-oxapentacyclo[14.2.1.01,13.04,12.05,9]nonadec-5-en-7-one is a natural product found in Diplospora fruticosa with data available.
Molecule SMILES: CCC(C)CCCCCCC(=O)NCc1ccc(O)c(OC)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: HomodihydrocapsaicinII is a natural product found in Capsicum annuum with data available.
Molecule SMILES: CN1CCC23c4c5ccc(OC6OC(C(=O)O)C(O)C(O)C6O)c4OC2C(O)C=CC3C1C5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Morphine-3-glucuronide is a morphinane alkaloid.
Molecule SMILES: CN1CCC23c4c5ccc(OC6OC(C(=O)O)C(O)C(O)C6O)c4OC2C(O)C=CC3C1C5

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Morphine-3-glucuronide is a natural product found in Papaver somniferum with data available.
Molecule SMILES: CC(=O)NC1C(OC2C(O)OC(CO)C(O)C2O)OC(CO)C(OC2OC(COC3(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O3)C(O)C(O)C2O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S,4S,5R,6R)-5-Acetamido-2-[[(2R,3R,4S,5R,6S)-6-[(2R,3S,4R,5R,6S)-5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-[(2S,3S,4S,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.
Molecule SMILES: COC1=CC2(C=CC1=O)CC(C)C(C)Cc1cc3c(c(OC)c12)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (6R,7R,9S)-2',10-dimethoxy-6,7-dimethylspiro[5,6,7,8-tetrahydrocyclohepta[f][1,3]benzodioxole-9,4'-cyclohexa-2,5-diene]-1'-one is a natural product found in Eupomatia laurina with data available.
Molecule SMILES: CCCCCCCC=CC=CC(=O)NC(C(=O)NC1CCCCNC(=O)C=CC(C)NC1=O)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Luminmycin A is a natural product found in Photorhabdus luminescens with data available.
Molecule SMILES: CC(=O)Oc1cc(OC(C)=O)cc(Oc2c(Oc3c(OC(C)=O)cc(OC(C)=O)cc3OC(C)=O)cc(OC(C)=O)cc2Oc2c(OC(C)=O)cc(Oc3c(OC(C)=O)cc(OC(C)=O)c(-c4c(OC(C)=O)cc(OC(C)=O)cc4OC(C)=O)c3OC(C)=O)cc2OC(C)=O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Fucotetraphlorethol K tetradecaacetate is a natural product found in Cystophora retroflexa with data available.
Molecule SMILES: CC1CCC2(C)C(C(=O)O)=CC(OC(=O)c3ccccc3)CC2C1(C)CCc1ccoc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (3R,4aR,5R,6R,8aS)-3-benzoyloxy-5-[2-(furan-3-yl)ethyl]-5,6,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-1-carboxylic acid is a natural product found in Dodonaea polyandra with data available.
Molecule SMILES: CC(C)C(=O)CC(C)(O)C1CCC2C3CC(O)C4CC(O)CCC4(C)C3=CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 24-northornasterol A is a bile acid.
Molecule SMILES: COC1CCC2CCN(C)C(=O)C(C)CN(C)C(=O)c3cccc(C#N)c3OCC1O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: LSM-40216 is an azamacrocycle and a lactam.
Molecule SMILES: COc1cc2oc(=O)ccc2cc1C(OC(=O)CC(C)C)C(O)C(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Angelol L is a natural product found in Angelica pubescens with data available.
Molecule SMILES: C#CCCCCCCCC1CCC2CCCCC(C)N12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Lehmizidine is a natural product found in Oophaga lehmanni with data available.
Molecule SMILES: CCC=CCC=CCC=CCC=CCC=CCCCC(=O)OCC(O)COP(=O)([O-])OCC[N+](C)(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: LysoPC(20:5(5Z,8Z,11Z,14Z,17Z)) is a lysophosphatidylcholine 20:5.
Molecule SMILES: CCC=CCC=CCC=CCC=CCC=CCCCC(=O)OCC(O)COP(=O)([O-])OCC[N+](C)(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: LysoPC(20:5(5Z,8Z,11Z,14Z,17Z)) is a natural product found in Homo sapiens with data available.
Molecule SMILES: C=CC(C)(C)C(NC(=O)C(C)C(O)C(C)C(O)CCCCCCCCCCCCC)C(=O)NC(C(=O)NC(C=O)C(=O)O)C(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2R,3R,4S,5R)-3,5-dihydroxy-2,4-dimethyloctadecanoyl]amino]-3,3-dimethylpent-4-enoyl]amino]-3-hydroxybutanoyl]amino]-3-oxopropanoic acid is a natural product found in Penicillium with data available.
Molecule SMILES: COc1ccc(CC(=O)O)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Homoveratric acid is a phenylacetic acid substituted at positions 3 and 4 by methoxy groups. It has a role as a human urinary metabolite and a human xenobiotic metabolite. It is a dimethoxybenzene and a member of phenylacetic acids.
Molecule SMILES: COc1ccc(CC(=O)O)cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Homoveratric acid is a natural product found in Olea europaea and Zingiber officinale with data available.
Molecule SMILES: CC=CC=CC(=O)c1cc(C(=O)O)c(OC)cc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5-Hexa-2,4-dienoyl-4-hydroxy-2-methoxybenzoic acid is a natural product found in Scytalidium album with data available.
Molecule SMILES: CC1=CCCC(C)C(=O)Cc2c(C)coc2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Furanogermenone is a germacrane sesquiterpenoid.
Molecule SMILES: CC1=CCCC(C)C(=O)Cc2c(C)coc2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: CID 13118284 is a natural product found in Curcuma amada, Curcuma aeruginosa, and other organisms with data available.
Molecule SMILES: CC(C)=CCCC1(C)OC1CCC(C)=CCCC1(C)C(CCCO)C(=C(C)C=O)CCC1(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2Z)-2-[(2R,3S,4S)-4-hydroxy-2-(3-hydroxypropyl)-3,4-dimethyl-3-[(E)-4-methyl-6-[(2R,3S)-3-methyl-3-(4-methylpent-3-enyl)oxiran-2-yl]hex-3-enyl]cyclohexylidene]propanal is a natural product found in Iris cristata with data available.
Molecule SMILES: C=C(N=C(O)C(N=C(O)C(Cc1cnc[nH]1)N=C(O)C(N=C(O)C(CO)N=C(O)C1CSC(C)C2N=C(O)C(C)N=C(O)C(N=C(O)C(CCCCN)N=C(O)C(CCSC)N=C(O)C(CC(=N)O)N=C(O)C3CSC(C)C(N=C(O)C(CCCCN)N=C(O)C4CSC(C)C(N=C(O)C5CSCC(N=C(O)C(=CC)N=C(O)C(N)C(C)CC)C(O)=NC(C(C)CC)C(O)=NC(=C)C(O)=NC(CC(C)C)C(O)=N5)C(=O)N5CCCC5C(O)=NCC(O)=N4)C(O)=NCC(O)=NC(C)C(O)=NC(CC(C)C)C(O)=NC(CCSC)C(O)=NCC(O)=N3)C(C)SCC(N=C2O)C(O)=NC(Cc2cnc[nH]2)C(O)=N1)C(C)CC)C(C)C)C(O)=NC(CCCCN)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: NA is a natural product found in Lactococcus lactis with data available.
Molecule SMILES: CC(C)C(N)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: D-valine is the D-enantiomer of valine. It is a valine and a D-alpha-amino acid. It is a conjugate base of a D-valinium. It is a conjugate acid of a D-valinate. It is an enantiomer of a L-valine. It is a tautomer of a D-valine zwitterion.
Molecule SMILES: CC1OC(OC2C(O)C(CO)OC(OC3C(C)OC(OC4C(O)C(CO)OC(OC5C(OC6C(C)OC(OC7C(O)C(CO)OC(OC8C(OC9C(C)OC(O)C(O)C9O)OC(CO)C(O)C8OC8OC(C)C(O)CC8O)C7O)C(O)C6O)OC(CO)C(O)C5OC5OC(C)C(O)CC5O)C4O)C(O)C3O)C2OC2OC(CO)C(O)C(O)C2O)C(O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap-(1->3)-alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp-(1->4)-alpha-L-Rhap is a polysaccharide that is a branched dodecasaccharide consisting of three repeating tetrasaccharide units; reported to be a possible epitope of the O-antigen polysaccharide in Salmonella.
Molecule SMILES: C=CC(C)(O)CCC1OOC(C=C(C)C)CC1=C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Chiliadenol C is a natural product found in Chiliadenus montanus with data available.
Molecule SMILES: CC(=O)OC1C(C)C(O)C=COC2(C)Oc3c(C)c([O-])c4c(O)c(cc(O)c4c3C2=O)NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 27-O-demethylrifamycin SV(1-) is a phenolate anion obtained by deprotonation of the 5-hydroxy group of 27-O-demethylrifamycin SV. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). It is a conjugate base of a 27-O-demethylrifamycin SV.
Molecule SMILES: O=c1[nH]cnc2c1ncn2C1OC(CO)C(OP(=O)(O)O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Inosine 3'-monophosphate is an inosine phosphate having a monophosphate group located at the 3'-position. It is an inosine phosphate and a purine ribonucleoside 3'-monophosphate.
Molecule SMILES: CC(C)c1cc2c(c(O)c1O)C13CCCC(C)(C)C1C(O)C2OC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 7beta,20-Epoxyabieta-8,11,13-triene-6alpha,11,12-triol is a natural product found in Premna serratifolia with data available.
Molecule SMILES: CC(Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cc(C(C)O)[nH]n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). This condition occurs in the majority of patients with advanced prostate cancer who have been treated with androgen receptor antagonists. Though prior treatment for prostate cancer has been successful for these patients, the cancer eventually progresses to become resistant to existing therapies. This warrants further treatment.  The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer. Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.
Molecule SMILES: CC(Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cc(C(C)O)[nH]n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Darolutamide is a formulation containing an androgen receptor (AR) antagonist with potential antineoplastic activity. Darolutamide binds to ARs in target tissues; subsequently, inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. This prevents binding to and transcription of AR-responsive genes that regulate prostate cancer cell proliferation. This ultimately leads to an inhibition of growth in AR-expressing prostate cancer cells.
Molecule SMILES: CC(Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cc(C(C)O)[nH]n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Darolutamide is a third generation, oral nonsteroidal antiandrogen used to treat nonmetastatic castration-resistant prostate cancer. Darolutamide is associated with a low rate of serum enzyme elevation during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice.
Molecule SMILES: CC(C=CC=C(C)C=CC1C(C)=CC(O)CC1(C)C)=CC=CC=C(C)C=CC=C(C=CC1=C(C)CC(O)CC1(C)C)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Loroxanthin is a natural product found in Euglena sanguinea, Corbicula japonica, and other organisms with data available.
Molecule SMILES: CC(CO)CCNc1ncnc2ncn(C3OC(CO)C(O)C(O)C3O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 7-(alpha-D-glucosyl)dihydrozeatin is an N-glycosyldihydrozeatin in which the glycosyl fragment is an alpha-D-glucopyranosyl residue located at position 7. It has a role as an Arabidopsis thaliana metabolite.
Molecule SMILES: COc1ccc(-c2coc3c(OC)c(OCC4(O)COC(OCC5OC(O)C(O)C(O)C5O)C4O)ccc3c2=O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 7-[[(3R,4R,5R)-3,4-dihydroxy-5-[[(2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy]oxolan-3-yl]methoxy]-8-methoxy-3-(4-methoxyphenyl)chromen-4-one is a natural product found in Mucuna birdwoodiana with data available.
Molecule SMILES: O=C(O)COc1ccc2c(-c3ccccc3F)noc2c1Br

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Brocrinat is an ethacrynic acid derivative with diuretic activity.
Molecule SMILES: O=C(OCC1OC(O)C(O)(COC(=O)c2cc(O)c(O)c(O)c2)C1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-C-(Galloyloxymethyl)-3-O,5-O-digalloyl-beta-D-ribofuranose is a natural product found in Castanea crenata, Cercidiphyllum japonicum, and other organisms with data available.
Molecule SMILES: O=C(O)C1OC(OC2C(COS(=O)(=O)O)OC(O)C(NS(=O)(=O)O)C2O)C(OS(=O)(=O)O)C(O)C1OC1OC(COS(=O)(=O)O)C(O)C(O)C1NS(=O)(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Alpha-D-GlcNS(6S)-(1->4)-alpha-L-IdoUA(2S)-(1->4)-D-GlcNS(6S) is a three-membered linear oligosaccharide sulfate that consists of a 2-O-sulfo-L-idopyranuronic acid residue flanked by two 6-O-sulfo-2-(sulfoamino)-D-glucopyranose residues, connected via alpha-(1->4)-linkages.