IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: COc1ccc(CC(O)C(=O)c2ccc(OC)cc2OC)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2'-O-methylodoratol is a member of the class of dihydrochalcones that is the 2'-O-methyl derivative of odoratol. It has a role as a plant metabolite. It is a member of dihydrochalcones, a dimethoxybenzene, a secondary alcohol and a secondary alpha-hydroxy ketone. It is functionally related to an odoratol.
Molecule SMILES: COc1ccc(CC(O)C(=O)c2ccc(OC)cc2OC)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: O-Methylodoratol is a natural product found in Acacia rubida and Acacia saxatilis with data available.
Molecule SMILES: C=C(C)C1C=CC(C)C(=O)C2CC(C)C(OC(C)=O)C2=CC(C)C(=O)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(2R,3S,3aE,5S,8R,9E,11R,12aS)-2,5,11-trimethyl-6,12-dioxo-8-prop-1-en-2-yl-1,2,3,5,7,8,11,12a-octahydrocyclopenta[11]annulen-3-yl] acetate is a natural product found in Jatropha multifida with data available.
Molecule SMILES: CC(C)=CCCC(C)C1CC(O)C(C)=CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2,10-Bisaboladiene-1,4-diol is a natural product found in Zingiber officinale with data available.
Molecule SMILES: CCC=CC1CC=CC=CC(O)CC(O)C(C)C=CCC(C)C=CC=C(C)C=CC(=O)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 22-But-1-enyl-14,16-dihydroxy-5,9,13-trimethyl-1-oxacyclodocosa-3,5,7,11,17,19-hexaen-2-one is a natural product found in Streptomyces albidoflavus with data available.
Molecule SMILES: CC(C)=CCc1c(O)c(O)cc2c(=O)c3c(O)c4c(cc3oc12)OC(C)C4(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: cudraxanthone M is a natural product found in Maclura tricuspidata with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(O)C1OC1OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Alpha-D-Galp-(1->4)-beta-D-Galp-(1->3)-alpha-D-GalpNAc is an amino trisaccharide in which two galactose residues, linked alpha(1->4), are linked beta(1->3) to an N-acetylgalactosamine residue. It is an amino trisaccharide and a galactosamine oligosaccharide.
Molecule SMILES: C=CCCCC1OC1CC=CCC1OC1CC1OC1CC=CCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2R,3R)-2-[(Z)-pent-2-enyl]-3-[[(2R,3R)-3-[(Z)-4-[(2R,3R)-3-pent-4-enyloxiran-2-yl]but-2-enyl]oxiran-2-yl]methyl]oxirane is a natural product found in Notheia anomala with data available.
Molecule SMILES: c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 4,7-diphenyl-1,10-phenanthroline is a member of the class of phenanthrolines that is 1,10-phenanthroline bearing two phenyl substituents at positions 4 and 7. It has a role as a chelator. It is a member of phenanthrolines and a member of benzenes.
Molecule SMILES: c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 4,7-Diphenyl-1,10-phenanthroline is a natural product found in Arabidopsis thaliana with data available.
Molecule SMILES: Cn1cc(-c2cc(S(C)(=O)=O)ccc2OCC2CC2)c2ccccc2c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Trotabresib is an orally bioavailable inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon oral administration, trotabresib preferentially binds to the second bromodomain (BD2) of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histones. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of proliferation in BET-overexpressing tumor cells. BET proteins (BRD2, BRD3, BRD4 and BRDT) are transcriptional regulators that contain two homologous bromodomains, the BD1 and BD2 domains. They play an important role during development and cellular growth.
Molecule SMILES: CC(C)NC(=O)Nc1ccc2c(c1)C(=O)N(C(C)CO)CC(C)C(CN(C)C(=O)c1ccccc1)OCCCCC(C)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: N-[[(3S,9S,10R)-12-[(2S)-1-hydroxypropan-2-yl]-3,10-dimethyl-13-oxo-16-[[oxo-(propan-2-ylamino)methyl]amino]-2,8-dioxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-9-yl]methyl]-N-methylbenzamide is an azamacrocycle and a lactam.
Molecule SMILES: C=CC1(C)CCC(C(C)C(=O)C(O)C=C(C)C)C12C(=O)Oc1cc(OC)ccc1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 1'-Ethenyl-3'-(4-hydroxy-6-methyl-3-oxohept-5-en-2-yl)-7-methoxy-1'-methylspiro[chromene-3,2'-cyclopentane]-2,4-dione is a natural product found in Ferula ammoniacum with data available.
Molecule SMILES: CCC=CCC=CCC=CCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCC=CCC=CCCCCC)COP(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: PA(20:2(11Z,14Z)/18:3(9Z,12Z,15Z)) is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: O=C1OC2OC(CO)C(O)C(OC(=O)c3cc(O)c(O)c(O)c3)C2OC(=O)c2cc(Oc3ccc(O)c(O)c3C(=O)OC3C(OC(=O)c4cc(O)c(O)c(Oc5c(C(=O)O)cc(O)c(O)c5O)c4)OC(CO)C(O)C3OC(=O)c3cc(O)c(O)c(O)c3)c(O)c(O)c2Oc2cc1cc(O)c2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 2-[5-[3-[2,3-Dihydroxy-6-[[4,5,13,21,22-pentahydroxy-14-(hydroxymethyl)-9,18-dioxo-12-(3,4,5-trihydroxybenzoyl)oxy-2,10,15,17-tetraoxatetracyclo[17.3.1.03,8.011,16]tricosa-1(23),3,5,7,19,21-hexaen-6-yl]oxy]benzoyl]oxy-5-hydroxy-6-(hydroxymethyl)-4-(3,4,5-trihydroxybenzoyl)oxyoxan-2-yl]oxycarbonyl-2,3-dihydroxyphenoxy]-3,4,5-trihydroxybenzoic acid is a natural product found in Tamarix aphylla with data available.
Molecule SMILES: C=C1CC2OC(=O)C(C)C2CC2(O)C(=C)C(O)CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1S,3aS,5aS,7S,8aR,9aR)-7,8a-dihydroxy-1-methyl-5,8-dimethylidene-1,3a,4,5a,6,7,9,9a-octahydroazuleno[6,5-b]furan-2-one is a natural product found in Arctotis fastuosa with data available.
Molecule SMILES: CC(C)CC1NC(=O)CNC(=O)C2CCCN2C(=O)C(C(C)O)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)NC(=O)C(CC(N)=O)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Cyclomontanin A is a homodetic cyclic peptide composed of L-alanyl, L-tryptophyl, L-threonyl, L-prolylglycyl, L-leucyl and L-asparaginyl residues linked in a sequence. It is isolated from the seeds of Annona montana and has been shown to exhibit anti-inflammatory activity. It has a role as a metabolite and an anti-inflammatory agent.
Molecule SMILES: CC(C)CC1NC(=O)CNC(=O)C2CCCN2C(=O)C(C(C)O)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)NC(=O)C(CC(N)=O)NC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: cyclomontanin A is a natural product found in Annona montana with data available.
Molecule SMILES: COc1ccccc1CCNC1CCC(C(C)(C)C)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 4-tert-butyl-N-[2-(2-methoxyphenyl)ethyl]-1-cyclohexanamine is a primary amine.
Molecule SMILES: O=C1OC(C(=O)O)C(c2ccc(O)c(O)c2)C1=Cc1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Megacerotonic acid is a natural product found in Megaceros flagellaris with data available.
Molecule SMILES: COc1cc2oc(=O)ccc2cc1C=CC1(C)CCC(C)=CC1c1cc2ccc(=O)oc2cc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 7-methoxy-6-[(E)-2-[(1S,2R)-2-(7-methoxy-2-oxochromen-6-yl)-1,4-dimethylcyclohex-3-en-1-yl]ethenyl]chromen-2-one is a natural product found in Thamnosma montana with data available.
Molecule SMILES: CC1(C=O)CCCC2(C)C1CCC13CC(CO)C(CCC12)C3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1S,4S,5R,9S,10R,13R,14R)-14-(hydroxymethyl)-5,9-dimethyltetracyclo[11.2.1.01,10.04,9]hexadecane-5-carbaldehyde is a natural product found in Annona squamosa and Annona glabra with data available.
Molecule SMILES: CC(CO)CCOc1ccc(C(=O)O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 4-[(3S)-4-hydroxy-3-methylbutoxy]benzoic acid is a natural product found in Turraeanthus africanus with data available.
Molecule SMILES: CC(C)=CCCC(C)C12CC=C(C)C1C2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1R)-2-methyl-5-[(2S)-6-methylhept-5-en-2-yl]bicyclo[3.1.0]hex-2-ene is a natural product found in Citrus limettioides with data available.
Molecule SMILES: CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCc1cc(O)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Geranylgeranylhydroquinone is a natural product found in Sarcotragus foetidus, Lactarius lignyotus, and Phacelia minor with data available.
Molecule SMILES: COc1ccc2c3c(n(C)c2c1)C1CC2C(C(C)=O)=COCC2C(C3=O)N1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (1S,12R,13R,18R)-17-acetyl-6-methoxy-3,20-dimethyl-15-oxa-3,20-diazapentacyclo[10.7.1.02,10.04,9.013,18]icosa-2(10),4(9),5,7,16-pentaen-11-one is a natural product found in Alstonia macrophylla with data available.
Molecule SMILES: C=CC1(C)C=C2C(=O)CC3C(C)(C)C(O)CCC3(C)C2CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S,4aS,4bR,7R,10aR)-7-ethenyl-2-hydroxy-1,1,4a,7-tetramethyl-2,3,4,4b,5,6,10,10a-octahydrophenanthren-9-one is a natural product found in Oryza sativa with data available.
Molecule SMILES: C=C1C(=CC=C2CCCC3(COC(C)=O)C2CCC3C(C)CCCC(C)C)CC(O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 18-acetoxy-1alpha-hydroxyvitamin D3 is a hydroxycalciol that is calciol with an additional hydroxy group at position C-1 and an acetoxy group at C-18. It has a role as a metabolite. It is a hydroxycalciol, a diol and a member of D3 vitamins.
Molecule SMILES: C=C1C(=CC=C2CCCC3(COC(C)=O)C2CCC3C(C)CCCC(C)C)CC(O)CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (5Z,7E)-(1S,3R)-18-acetoxy-9,10-seco-5,7,10(19)-cholestatriene-1,3-diol is a natural product found in Trypanosoma brucei with data available.
Molecule SMILES: O=C(CCn1cnc2ccccc2c1=O)Nc1nc2c(s1)CCCC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-(4-oxo-3-quinazolinyl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)propanamide is a member of quinazolines.
Molecule SMILES: CC(C)C#Cc1ccc(C2C(CO)N3C(=O)CN(C(=O)c4ccc5c(c4)OCO5)CC23)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (6S,7R,8S)-4-[1,3-benzodioxol-5-yl(oxo)methyl]-8-(hydroxymethyl)-7-[4-(3-methylbut-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one is a member of benzenes, a member of azetidines and a ring assembly.
Molecule SMILES: O=C(Nc1ccc2c(c1)OCO2)NC1C=CC(CC(=O)N2CCN(c3ccccc3)CC2)OC1CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 1-(1,3-benzodioxol-5-yl)-3-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]-3,6-dihydro-2H-pyran-3-yl]urea is a member of piperazines.
Molecule SMILES: C=CC1(C)CCC(C(C)C)C(O)C1C(=C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Shyobunol is a natural product found in Cistus creticus and Acorus calamus with data available.
Molecule SMILES: CC(=O)NC1C(OC2C(O)C(COC3OC(CO)C(OC4OC(CO)C(O)C(OC5OC(CO)C(O)C(OC6OC(CO)C(O)C(O)C6OC6OC(C)C(O)C(O)C6O)C5NC(C)=O)C4O)C(O)C3NC(C)=O)OC(O)C2NC(C)=O)OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: N-[(2R,3R,4R,5S,6R)-2-[[(2R,3R,4R,5R)-5-Acetamido-4-[(2R,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,6-dihydroxyoxan-2-yl]methoxy]-5-[(2S,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide is an amino sugar.
Molecule SMILES: CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(OC6OCC(O)C(O)C6OC6OC(CO)C(O)C(OC7OC(CO)C(O)C(O)C7O)C6O)C(C)(CO)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid is a natural product found in Aralia elata with data available.
Molecule SMILES: COc1ccc2[nH]cc(C(=O)CNc3nc(C)cs3)c2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1-(5-methoxy-1H-indol-3-yl)-2-[(4-methyl-2-thiazolyl)amino]ethanone is a member of indoles.
Molecule SMILES: CN(C)CC(=O)Nc1ccc2c(c1)C1CC(CC(=O)NCc3ccncc3)OC(CO)C1O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 2-[(1R,3R,4aS,9aR)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(pyridin-4-ylmethyl)acetamide is an amino acid amide.
Molecule SMILES: NC(CC(O)C(O)C(=O)COP(=O)(O)O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoic acid is a heptanoic acid having an amino-substituent at the 2-position, hydroxy-substituents at the 4- and 5-positions, an oxo-substituent at the 6-position and a phosphonooxy-substituent at the 7-position. It is an oxo monocarboxylic acid and a monoalkyl phosphate. It is functionally related to a heptanoic acid. It is a conjugate acid of a 2-azaniumyl-4,5-dihydroxy-6-oxo-7-(phosphonatooxy)heptanoate(2-).
Molecule SMILES: COc1ccc(NC(=O)C(CCCCN)NC(=O)c2cc(NC(=O)C(CCCCN)NC(=O)c3cc(NC(=O)C(CCCCN)NC(=O)c4cc(NC(=O)C(N)CCCCN)ccc4OC)ccc3OC)ccc2OC)cc1C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Delparantag has been used in trials studying the treatment of Angioplasty, Coronary Artery Disease (CAD), and Percutaneous Coronary Intervention.
Molecule SMILES: COc1ccc(NC(=O)C(CCCCN)NC(=O)c2cc(NC(=O)C(CCCCN)NC(=O)c3cc(NC(=O)C(CCCCN)NC(=O)c4cc(NC(=O)C(N)CCCCN)ccc4OC)ccc3OC)ccc2OC)cc1C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Delparantag is an amidobenzoic acid.
Molecule SMILES: OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Quetiapine is an atypical antipsychotic used in the treatment of schizophrenia and bipolar disorder. Use of quetiapine has been associated with serum aminotransferase elevations and in rare instances with clinically apparent acute liver injury.
Molecule SMILES: OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Quetiapine is a dibenzothiazepine, a N-alkylpiperazine and a N-arylpiperazine. It has a role as a serotonergic antagonist, a dopaminergic antagonist, a histamine antagonist, an adrenergic antagonist and a second generation antipsychotic.
Molecule SMILES: OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [Clozapine] and [Olanzapine].
Molecule SMILES: OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Quetiapine is an Atypical Antipsychotic.
Molecule SMILES: OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Quetiapine is a dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors.