IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: [NH3+]C(CC(=O)[O-])c1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 3-amino-3-(4-hydroxyphenyl)propanoic acid zwitterion is zwitterionic form of 3-amino-3-(4-hydroxyphenyl)propanoic acid arising from migration of a proton fron the carboxy to the amino group; major species at pH 7.3. It has a role as a bacterial metabolite. It is a tautomer of a 3-amino-3-(4-hydroxyphenyl)propanoic acid.
Molecule SMILES: [NH3+]C(CC(=O)[O-])c1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 3-Amino-3-(4-hydroxyphenyl)propanoate is a natural product found in Daphnia pulex with data available.
Molecule SMILES: CC(=CC(=O)O)CCC1C(CO)=CCC2C(C)(C)CC(O)CC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (E)-5-[(1S,4aR,7R,8aR)-7-hydroxy-2-(hydroxymethyl)-5,5,8a-trimethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]-3-methylpent-2-enoic acid is a natural product found in Dodonaea microzyga with data available.
Molecule SMILES: CCSc1n[nH]c(C(F)(F)F)n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 5-(Ethylthio)-3-(trifluoromethyl)-1H-1,2,4-triazole is an aryl sulfide.
Molecule SMILES: C=CCc1ccc(OC(=O)C(C)=CC)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 2-Butenoic acid, 2-methyl-, 4-(2-propenyl)phenyl ester, (2Z)- is a natural product found in Pimpinella isaurica with data available.
Molecule SMILES: CC1CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(=O)C(C)(C)C5CCC43C)C2C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Urs-12-ene-3,11-dione is a natural product found in Boswellia sacra and Canarium zeylanicum with data available.
Molecule SMILES: CC1CC(C(=O)NC(CO)CCCN=C(N)N)N(C(=O)C(Cc2ccc(O)cc2)NC(=O)C(O)CCc2ccc(O)cc2)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Dihydrospumigin K is a natural product found in Sphaerospermopsis torques-reginae with data available.
Molecule SMILES: COC(=O)C12CCC(C)(C(=O)O)CC1C1=CCC3C4(C)CCC(OC5OC(CO)C(O)C(O)C5OC5OC(C)C(O)C(O)C5O)C(C)(C)C4CCC3(C)C1(C)CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (2R,4aR,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4a-methoxycarbonyl-2,6a,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-2-carboxylic acid is a natural product found in Taverniera aegyptiaca with data available.
Molecule SMILES: CC(=O)OC1CCC(C)OC12OCC1=C(CC(O)C(C)(O)C1=O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Sargassopenilline F is a natural product found in Penicillium thomii with data available.
Molecule SMILES: CCC(C)CCCCC([O-])=NC(CCNCS(=O)(=O)O)C(=O)NC(C(=O)NC(CCNCS(=O)(=O)O)C([O-])=NC1CCNC(=O)C(C(C)O)NC(=O)C(CCNCS(=O)(=O)O)N=C([O-])C(CCNCS(=O)(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)N=C([O-])C(CCNCS(=O)(=O)O)N=C1[O-])C(C)O.[Na+].[Na+].[Na+].[Na+].[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Colistimethate is a broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria. Colistimethate is a mixture of methanesulfonate derivatives of cyclic polypeptides colistin A and B from Bacillus colistinus or B. polymyxa. Colistin functions as a surfactant which penetrates into and disrupts the bacterial cell membrane, thereby resulting in bactericidal effect.
Molecule SMILES: CC(=O)C=C1OC(=O)C(C)=C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Xanthofusin is a natural product found in Fusicoccum with data available.
Molecule SMILES: CCCCCC=CCC=CCCCCCCCC(=O)OC1C=C2C3CCC(C(C)C=CC(C)C(C)C)C3(C)CCC2C2(C)CCC(O)CC12O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (22E)-5alpha-Ergosta-7,22-diene-3beta,5,6beta-triol 6-linolate is a natural product found in Aspergillus awamori and Catathelasma imperiale with data available.
Molecule SMILES: CC(C)=CC=CC(C)=CC=CC(C)=C1C(=O)CC2C1(C)CCC1C(C)(CO)C(O)CCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (3E,3aS,5aR,6S,7R,9aR,9bS)-3-[(3E,5E,7E)-6,10-dimethylundeca-3,5,7,9-tetraen-2-ylidene]-7-hydroxy-6-(hydroxymethyl)-3a,6,9a-trimethyl-1,4,5,5a,7,8,9,9b-octahydrocyclopenta[a]naphthalen-2-one is a natural product found in Rhabdastrella globostellata with data available.
Molecule SMILES: CC1(C(=O)O)CCCC2(C)C3CCC(O)C=C3CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1R,4aR,4bR,7S,10aR)-7-hydroxy-1,4a-dimethyl-2,3,4,4b,5,6,7,9,10,10a-decahydrophenanthrene-1-carboxylic acid is a natural product found in Agathis macrophylla with data available.
Molecule SMILES: COc1cc(C2OCC3C(c4ccc(OC(C)=O)c(OC)c4)OCC23)ccc1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (+)-Pinoresinol diacetate is a natural product found in Araucaria angustifolia with data available.
Molecule SMILES: CNCC1Oc2c(NC(=O)Nc3ccc(C(F)(F)F)cc3)cccc2C(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 1-[(2R,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-3-[4-(trifluoromethyl)phenyl]urea is a member of ureas.
Molecule SMILES: COc1c2ccoc2c(OCC(O)C(C)(C)O)c2oc(=O)ccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 9-[(2S)-2,3-dihydroxy-3-methylbutoxy]-4-methoxyfuro[3,2-g]chromen-7-one is a natural product found in Angelica tarokoensis, Angelica pubescens, and Angelica dahurica with data available.
Molecule SMILES: C=C1COC(=O)C12CC1(C)C(C)CCC(OC(C)=O)C1C2OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Bakkenolide L is a natural product found in Petasites formosanus and Petasites tatewakianus with data available.
Molecule SMILES: C=CC(=CC(=O)CC(C)CC(C)CCC(O)C(C)C(=O)CC(O)C(C)C(C)OC(=O)CC(C)C1=C(C)C(=O)OC1=O)CC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(2R,3S,4R,7S,8S,11S,13R,16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl] (3R)-3-(4-methyl-2,5-dioxofuran-3-yl)butanoate is a natural product found in Streptomyces griseochromogenes with data available.
Molecule SMILES: C=CC(C=Cc1ccc(O)cc1)c1ccc(OC)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 5-[(1Z,3R)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]-2-methoxyphenol is a natural product found in Asparagus cochinchinensis with data available.
Molecule SMILES: OCC1OC(Oc2cc(O)cc3[o+]c(-c4ccc(O)c(O)c4)c(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)cc23)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Cyanidin-3-sophoroside-5-glucoside is an anthocyanidin glycoside.
Molecule SMILES: OCC1OC(Oc2cc(O)cc3[o+]c(-c4ccc(O)c(O)c4)c(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)cc23)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Cyanidin 3-sophoroside-5-glucoside is a natural product found in Brassica oleracea, Ajuga reptans, and Ipomoea batatas with data available.
Molecule SMILES: O=S(=O)(O)Oc1ccc2ccccc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 2-naphthyl sulfate is an aryl sulfate that is naphthalene in which the hydrogen at position 2 is replaced by a sulfooxy group. It is an aryl sulfate and a member of naphthalenes. It is functionally related to a 2-naphthol. It is a conjugate acid of a 2-naphthyl sulfate(1-).
Molecule SMILES: CC(CCC(=O)O)C1CCC2C3C(O)C(O)C4CC(O)CCC4(C)C3CCC12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 3beta,6alpha,7beta-Trihydroxy-5beta-cholan-24-oic acid is a bile acid.
Molecule SMILES: CCC(C)C(=O)OC1c2c(C)coc2CC2=CCCC(C)(O)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: [(4R,4aR,5S)-5-hydroxy-3,4a,5-trimethyl-4,6,7,9-tetrahydrobenzo[f][1]benzofuran-4-yl] (2S)-2-methylbutanoate is a natural product found in Senecio elegans with data available.
Molecule SMILES: COc1cc(O)cc(C)c1C(=O)OC1C(O)C(CO)OC1n1ccc(=O)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Kipukasin H is a natural product found in Aspergillus versicolor with data available.
Molecule SMILES: CC=C(C)C=CC1C(C)(O)CCC2C(C)(C)CCCC21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (1R,2R,4aS,8aS)-2,5,5,8a-tetramethyl-1-[(1Z,3E)-3-methylpenta-1,3-dienyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol is a natural product found in Abies sibirica with data available.
Molecule SMILES: C=CC(C)CC(C)C(=O)c1c(O)c(OC)c(OC)[nH]c1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Nbri-23477B is a natural product found in Penicillium atramentosum with data available.
Molecule SMILES: Nc1c[nH]c[n+]1C1OC(COP(=O)([O-])[O-])C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 5-amino-1-(5-phosphonato-beta-D-ribosyl)imidazol-3-ium is an organophosphate oxoanion obtained by deprotonation of the phosphate OH groups as well as protonation of the endocyclic nitrogen at position 3 in the imidazole ring of 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). It is a conjugate base of a 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole.
Molecule SMILES: C=CC1(C)Cc2occ(C)c2C2OC(=O)C(=C)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Isolinderalactone is a member of benzofurans. It has a role as a metabolite.
Molecule SMILES: C=CC1(C)Cc2occ(C)c2C2OC(=O)C(=C)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Isolinderalactone is a natural product found in Neolitsea villosa, Neolitsea hiiranensis, and other organisms with data available.
Molecule SMILES: OCC(O)C1OC(OC2C(O)C(O)OC2C(O)CO)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Beta-D-Galf-(1->3)-beta-D-Galf is a beta-D-Galf-(1->3)-D-Galf in which the carbon bearing the anomeric hydroxy group has beta configuration. It is functionally related to a beta-D-galactofuranose.
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)OC(CO)COC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Regaloside H is a natural product found in Lilium auratum, Lilium pensylvanicum, and Lilium mackliniae with data available.
Molecule SMILES: Cc1c(C(=O)OCC(=O)c2c(N)n(CC(C)C)c(=O)n(C)c2=O)oc2ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 3-methyl-2-benzofurancarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester is a member of benzofurans.
Molecule SMILES: CC(C)=CC(=O)OC1CCC2(C)C(CC(O)C3(C)C2CCC24CC23CCC4C2COC(C(C)(C)O)C(O)C2)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: [(1S,2R,3R,5R,7R,10S,11R,14R,15S)-3-hydroxy-15-[(3S,5R,6R)-5-hydroxy-6-(2-hydroxypropan-2-yl)oxan-3-yl]-2,6,6,10-tetramethyl-7-pentacyclo[12.3.1.01,14.02,11.05,10]octadecanyl] 3-methylbut-2-enoate is a natural product found in Toona sinensis with data available.
Molecule SMILES: CCOc1cc(S(=O)(=O)N2CC=C(c3ccc(F)cc3)CC2)c(OCC)cc1-n1cnnn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 1-[2,5-diethoxy-4-(1-tetrazolyl)phenyl]sulfonyl-4-(4-fluorophenyl)-3,6-dihydro-2H-pyridine is a member of tetrazoles.
Molecule SMILES: COc1c(Cl)c(C)c(Br)c(O)c1C(=O)c1c(C=O)c(O)cc(O)c1CC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Pestalone G is a natural product found in Pestalotiopsis neglecta with data available.
Molecule SMILES: CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(CO)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (3R,4R,4aR,6aR,6aS,6bR,8aR,10S,12aR,14bR)-4a-(hydroxymethyl)-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-3,4,10-triol is a natural product found in Pittosporum angustifolium with data available.
Molecule SMILES: Cc1cc(O)c2c(=O)c3c(oc2c1)C(O)CC3O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1S,3R)-6-Methyl-1,3,8-trihydroxy-1,2,3,9-tetrahydrocyclopenta[b][1]benzopyran-9-one is a natural product found in Fimetariella with data available.
Molecule SMILES: COc1cc(C2Oc3ccc(CCCO)cc3OC2CO)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 4-[(2R,3R)-3-(hydroxymethyl)-6-(3-hydroxypropyl)-2,3-dihydro-1,4-benzodioxin-2-yl]-2-methoxyphenol is a natural product found in Morinda citrifolia and Juniperus brevifolia with data available.
Molecule SMILES: O=C(OCC1OC(Oc2cc(O)cc(O)c2)C(O)C(O)C1O)c1cc(O)c(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 3,5-Dihydroxyphenyl 1-O-(6-O-galloyl-beta-D-glucopyranoside) is a glycoside.
Molecule SMILES: O=C(CC1CCC2C(COCC(O)CN2Cc2ccccc2F)O1)NC1CCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2-[(3S,6aR,8S,10aR)-1-[(2-fluorophenyl)methyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocin-8-yl]-N-cyclobutylacetamide is an aromatic amine.
Molecule SMILES: CCC(C)C=C(C)C=CC1=CC2=CC(=O)C3(C)OC(=O)C(C(C)=O)=C3C2=CN1CCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Peniazaphilone A is a natural product found in Penicillium with data available.
Molecule SMILES: CC1(C)C=Cc2cc(C(=O)C=Cc3ccc(O)cc3)c(O)cc2O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 1-(7-Hydroxy-2,2-dimethylchromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one is a natural product found in Broussonetia papyrifera and Cullen corylifolium with data available.
Molecule SMILES: CC1=C(CO)C(=O)OC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Withaferin A is a withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity. It has a role as an antineoplastic agent and an apoptosis inducer. It is a delta-lactone, a 4-hydroxy steroid, an enone, an ergostanoid, a secondary alcohol, a withanolide, a 27-hydroxy steroid, a primary alcohol and an epoxy steroid.
Molecule SMILES: CC1=C(CO)C(=O)OC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ashwagandha is a popular Ayurvedic herb used as a general tonic, to increase energy and reduce stress. Ashwagandha has not been implicated in causing serum enzyme elevations during therapy, but recently has been implicated in rare cases of clinically apparent liver injury.
Molecule SMILES: CC1=C(CO)C(=O)OC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Withaferin A is a natural product found in Vassobia breviflora, Withania somnifera, and other organisms with data available.
Molecule SMILES: COC12OC(C)(C)C3CC31C(O)CC(=CC(C)O)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (1aR,3aS,5E,7S,7aR)-7-hydroxy-5-[(2S)-2-hydroxypropylidene]-3a-methoxy-2,2-dimethyl-1,1a,6,7-tetrahydrocyclopropa[c][1]benzofuran-4-one is a natural product found in Lachnum papyraceum with data available.
Molecule SMILES: NC(=O)OCC1c2c(O)cc(CO)cc2N2CC3NC3C1(O)O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(8R,9R,10S,12S)-6,9-dihydroxy-4-(hydroxymethyl)-14-oxa-1,11-diazatetracyclo[7.4.1.02,7.010,12]tetradeca-2(7),3,5-trien-8-yl]methyl carbamate is a natural product found in Streptomyces with data available.
Molecule SMILES: COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Aliskiren is a unique antihypertensive agent that acts by direct inhibition of renin and has only recently been introduced into clinical practice. Aliskiren has been linked to rare instances of serum aminotransferase elevations during therapy and rare cases of idiosyncratic, clinically apparent liver injury.
Molecule SMILES: COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Aliskiren is a monomethoxybenzene compound having a 3-methoxypropoxy group at the 2-position and a multi-substituted branched alkyl substituent at the 4-position. It has a role as an antihypertensive agent. It is a monomethoxybenzene and a monocarboxylic acid amide.
Molecule SMILES: COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents.
Molecule SMILES: COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Aliskiren is a Renin Inhibitor. The mechanism of action of aliskiren is as a Renin Inhibitor.