IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=CC(C)CC(C)=CC=CC(C)NC(=O)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Haliamide is a natural product found in Haliangium ochraceum with data available.
Molecule SMILES: C=C1C(=O)OC2CC(C)C(CCC(C)=O)=CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (3aS,7S,8aS)-7-methyl-3-methylidene-6-(3-oxobutyl)-4,7,8,8a-tetrahydro-3aH-cyclohepta[b]furan-2-one is a natural product found in Telekia speciosa with data available.
Molecule SMILES: O=S(=O)(NC1CCC(CCn2cc(C3CC3)nn2)OC1CO)c1ccc(F)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: N-[(2S,3S,6S)-6-[2-(4-cyclopropyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-4-fluorobenzenesulfonamide is a C-glycosyl compound.
Molecule SMILES: CC1=CC2C(C(C)C)CCC(C)(O)C2CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (+)-T-Cadinol is a natural product found in Aglaia foveolata, Thulinella chrysantha, and other organisms with data available.
Molecule SMILES: COc1c2ccoc2nc2c(OC)c(OCC(O)C(C)(C)O)ccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (R)-1-((4,8-dimethoxyfuro[2,3-b]quinolin-7-yl)oxy)-3-methylbutane-2,3-diol is a natural product found in Haplophyllum ramosissimum, Orixa japonica, and other organisms with data available.
Molecule SMILES: CC(C)C1CCC(CO)=CC1C=C(CO)C(=O)OCC1(O)CCC(C(C)C)C2C=C(C(=O)O)COC(=O)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (5aS,6R,9S,9aS)-9-hydroxy-9-[[(E)-2-(hydroxymethyl)-3-[(1R,6R)-3-(hydroxymethyl)-6-propan-2-ylcyclohex-2-en-1-yl]prop-2-enoyl]oxymethyl]-1-oxo-6-propan-2-yl-3,5a,6,7,8,9a-hexahydro-2-benzoxepine-4-carboxylic acid is a natural product found in Trichoderma virens with data available.
Molecule SMILES: Cc1cc2c(c(O)c1OC1OC(CO)C(O)C(O)C1O)C(=O)c1c(O)cccc1C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Kwanzoquinone C is a natural product found in Hemerocallis fulva with data available.
Molecule SMILES: COC(CCC(C)C1OC23CC(OC(=O)CC(C(C)O)OC(=O)CC(O)(O2)C(C)CC3(C)C)C1C)c1cccc(OC(C)=O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: [3-[(1R,4S)-4-[(1S,3R,4S,5S,9R,13S,14R)-13-hydroxy-9-[(1S)-1-hydroxyethyl]-4,14,16,16-tetramethyl-7,11-dioxo-2,6,10,17-tetraoxatricyclo[11.3.1.11,5]octadecan-3-yl]-1-methoxypentyl]phenyl] acetate is a natural product found in Gracilaria coronopifolia with data available.
Molecule SMILES: CC1OC(OC2C(OCC3OC(Oc4c(-c5ccc(O)cc5)oc5cc(O)cc(O)c5c4=O)C(O)C(O)C3O)OC(C)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Kaempferol 3-(2''-rhamnosylrutinoside) is a member of flavonoids and a glycoside.
Molecule SMILES: C=C1C(=O)OC2C1C(O)CC1(C)C(OC(=O)C(C)=CC)C(O)C=C(C)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [(3aR,4S,5aR,6R,7R,9aS,9bR)-4,7-dihydroxy-5a,9-dimethyl-3-methylidene-2-oxo-4,5,6,7,9a,9b-hexahydro-3aH-benzo[g][1]benzofuran-6-yl] (E)-2-methylbut-2-enoate is a natural product found in Dimerostemma brasilianum with data available.
Molecule SMILES: C=C(C)C1(O)CCC2(C)CC=C(C=O)CCC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (3R,3aS,8aS)-3-hydroxy-8a-methyl-3-prop-1-en-2-yl-1,2,3a,4,5,8-hexahydroazulene-6-carbaldehyde is a natural product found in Rosa rugosa with data available.
Molecule SMILES: COC1=C2c3ccc(OC)c(OC)c3C(=O)N2CCc2cc3c(cc21)OCO3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2,7,8-Trimethoxy-17,19-dioxa-11-azapentacyclo[12.7.0.03,11.04,9.016,20]henicosa-1(21),2,4(9),5,7,14,16(20)-heptaen-10-one is a natural product found in Berberis darwinii with data available.
Molecule SMILES: CC=Cc1ccc2c(c1OC)OCO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: E-Isocroweacin is a member of benzodioxoles.
Molecule SMILES: CC(=O)OC1C(OC2CCC34CC35CCC3(C)C(C6(C)CCC(C(C)(C)O)O6)C(O)CC3(C)C5CC(OC3OC(C)C(O)C(O)C3OC(C)=O)C4C2(C)C)OCC(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: [(2S,3R,4S,5R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-9-[(2R,3R,4R,5R,6S)-3-acetyloxy-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]-4,5-dihydroxyoxan-3-yl] acetate is a natural product found in Astragalus coluteocarpus with data available.
Molecule SMILES: C=C(C)C1CCC(C)=C2CCC(C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Delta-guaiene is a carbobicyclic compound and sesquiterpene that is 1,2,3,3a,4,5,6,7-octahydroazulene which is substituted by methyl groups at positions 3 and 8 and by a (prop-1-en-2-yl group at position 5 (the 3S,3aS,5R enantiomer). It has a role as a platelet aggregation inhibitor and a plant metabolite. It is a sesquiterpene and a carbobicyclic compound.
Molecule SMILES: C=C(C)C1CCC(C)=C2CCC(C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: delta-Guaiene is a natural product found in Kunzea salina, Helichrysum odoratissimum, and other organisms with data available.
Molecule SMILES: CCOC(=O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(OCC(=O)O)ccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 6-O-(carboxymethyl)fluorescein ethyl ester is a carboxylic ester that is the ethyl ester of fluorescein in its ring-opened acid form and substituted on one of the oxygen functions of the xanthene nucleus by a carboxymethyl group. It has a role as a fluorescent probe. It is an ethyl ester and a dicarboxylic acid monoester. It is functionally related to a fluorescein (acid form).
Molecule SMILES: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Carvedilol is a unique antihypertensive medication with activity against both alpha- and beta-adrenergic receptors. Carvedilol has been linked to at least one instance of clinically apparent liver injury.
Molecule SMILES: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Carvedilol is a member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure. It has a role as a beta-adrenergic antagonist, an antihypertensive agent, an alpha-adrenergic antagonist, a vasodilator agent and a cardiovascular drug. It is a member of carbazoles, a secondary alcohol and a secondary amino compound.
Molecule SMILES: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R(+) enantiomer is both a beta and alpha-1 adrenoceptor blocker. It is currently used to treat heart failure, left ventricular dysfunction, and hypertension. The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the treatment of moderate hypertension.  Carvedilol was granted FDA approval on 14 September 1995.
Molecule SMILES: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Carvedilol is an alpha-Adrenergic Blocker and beta-Adrenergic Blocker. The mechanism of action of carvedilol is as an Adrenergic alpha-Antagonist and Adrenergic beta1-Antagonist and Adrenergic beta2-Antagonist.
Molecule SMILES: COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Carvedilol is a synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04)
Molecule SMILES: C=CC1(C)CCC2=C(C(=O)C=C3C(C)(C)CCCC32O)C1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Aspewentin M is a natural product found in Aspergillus wentii with data available.
Molecule SMILES: C=CC1(C)CCC(C(C)C(=O)CC(O)C(=C)C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (2S,5R)-2-[(2S,5R)-5-ethenyl-5-methyloxolan-2-yl]-5-hydroxy-6-methylhept-6-en-3-one is a natural product found in Tanacetum vulgare with data available.
Molecule SMILES: C=C1CCC2C(C)C(=O)OC2C(O)C2(C)CCC1O2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1S,2R,3S,6S,7S,11S)-2-hydroxy-1,6-dimethyl-10-methylidene-4,14-dioxatricyclo[9.2.1.03,7]tetradecan-5-one is a natural product found in Achillea millefolium and Achillea millefolium var. millefolium with data available.
Molecule SMILES: COC(=O)C(O)C1C2(C)CC3(OC(C)=O)C4C(OC)(OC56CC(=O)OC(c7ccoc7)C5(C)CCC(C13C)C46O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Rel-Khayseneganin H is a natural product found in Khaya senegalensis with data available.
Molecule SMILES: COc1ccc(O)c(C(CO)CO)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 2-(2'-Hydroxy-5'-methoxyphenyl)propane-1,3-diol is a natural product found in Cotula coronopifolia with data available.
Molecule SMILES: Cc1cc(CO)c(O)c(C(=O)CC2CC(=O)NC(=O)C2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 2,6-Piperidinedione, 4-(2-(2-hydroxy-3-(hydroxymethyl)-5-methylphenyl)-2-oxoethyl)- is a natural product found in Streptomyces albovinaceus with data available.
Molecule SMILES: C=C1C2CCC(C(=O)O)C23CCC(C3)C1(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (1S,2S,5S,8R)-7,7-dimethyl-6-methylidenetricyclo[6.2.1.01,5]undecane-2-carboxylic acid is a natural product found in Artemisia annua with data available.
Molecule SMILES: Nc1ncnc2c1ncn2C1OC(COP(=O)([O-])[O-])C(O)C1O.[Na+].[Na+]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Vidarabine Sodium Phosphate is a sodium phosphate salt form of vidarabine, a nucleoside analog with activity against herpes simplex virus and varicella zoster virus. Vidarabine is converted to a monophosphate by viral thymidine kinase and is further modified to a triphosphate form by host enzymes. Vidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication.
Molecule SMILES: C=CCNC(N)=S

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Allylthiourea is a white crystalline solid with a slight garlic odor. (NTP, 1992)
Molecule SMILES: C=CCNC(N)=S

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Allylthiourea is a thiourea with a prop-2-enyl group attached to one of the amines. It has a role as a metabolite. It is functionally related to a thiourea.
Molecule SMILES: OCC1OC(c2c(O)cc3c(c2O)C(c2ccc(O)cc2)C2c4cc(O)cc5c4C(c4cc(O)cc(O)c4C(c4ccc(O)cc4)C32)C(c2ccc(O)cc2)O5)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2S,3S,10R,11R,18R,19R)-3,11,19-tris(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-20-oxahexacyclo[16.6.1.02,10.04,9.012,17.021,25]pentacosa-1(25),4,6,8,12(17),13,15,21,23-nonaene-5,7,13,15,23-pentol is a natural product found in Shorea hemsleyana with data available.
Molecule SMILES: Oc1ccc2ccc3cccc4ccc1c2c34

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 1-Hydroxypyrene is a member of pyrenes.
Molecule SMILES: CC(C)NC(=O)NC1CCC(CCNC(=O)C2CCOCC2)OC1CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: N-[2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[[oxo-(propan-2-ylamino)methyl]amino]-2-oxanyl]ethyl]-4-oxanecarboxamide is a C-glycosyl compound.
Molecule SMILES: C=C(C#Cc1cc(OC2OC(C)C(O)C(O)C2O)ccc1O)CCC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Pestalotioquinoside C is a natural product found in Pestalotiopsis neglecta with data available.
Molecule SMILES: NC(=O)CCCCC(CCS)SC(=O)CCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: (S)-Succinyldihydrolipoamide is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Molecule SMILES: CC(C)C1CC(O)C(C)C2(C=C(CO)C(=O)C2)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Flammuspirone H is a natural product found in Flammulina velutipes with data available.
Molecule SMILES: CC(O)CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC1CC(=O)OCC2OC(OC(CCCCCCCCCCCCCC(CCCCCC(C)O)OC3OC(CO)C(O)C(O)C3O)CC(=O)OCC3OC(O1)C(O)C(O)C3O)C(O)C(O)C2O)OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 9,10,11,20,21,22-Hexahydroxy-3-[20-hydroxy-14-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhenicosyl]-14-[29-hydroxy-14-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxytriacontyl]-2,6,13,17,23,24-hexaoxatricyclo[17.3.1.18,12]tetracosane-5,16-dione is a natural product found in Streptomyces microflavus with data available.
Molecule SMILES: CCC(C)C(N=C(O)C(C)(C)N=C(O)C(CCC(=N)O)N=C(O)C(C)(C)N=C(O)C(C)(C)N=C(O)C(C)N=C(O)C(C)(C)N=C(O)C1CCCN1C(=O)C(C)(C)N=C(C)O)C(O)=NC(C)(C)C(O)=NCC(O)=NC(CC(C)C)C(O)=NC(C)(C)C(=O)N1CCCC1C(O)=NC(C(O)=NC(C)(C)C(O)=NC(C)(C)C(O)=NC(CCC(=N)O)C(O)=NC(CCC(=N)O)C(O)=NC(CO)Cc1ccccc1)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Polysporin C is a natural product found in Trichoderma polysporum with data available.
Molecule SMILES: CC1=CC2C=CCC(C)CCCC(O)C=CC(=O)C23C(=O)NC(Cc2ccccc2)C3C1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Deoxaphomin C is a natural product found in Phoma with data available.
Molecule SMILES: OCC1OC(SC2OC(CO)C(O)C(n3cc(-c4cccc(F)c4)nn3)C2O)C(O)C(n2cc(-c3cccc(F)c3)nn2)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: TD139 has been investigated for the treatment of Idiopathic Pulmonary Fibrosis.
Molecule SMILES: OCC1OC(SC2OC(CO)C(O)C(n3cc(-c4cccc(F)c4)nn3)C2O)C(O)C(n2cc(-c3cccc(F)c3)nn2)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Olitigaltin is an inhaled, small molecule inhibitor of galectin-3 (Gal-3), with potential anti-fibrotic activity. Upon administration, olitigaltin inhibits the activity of Gal-3. This may prevent the activation of alveolar macrophages and fibroblasts, and the resulting fibrosis in the lungs. Gal-3, a beta-galactoside-binding lectin, is expressed in multiple cell types including macrophages, fibroblasts, activated T-lymphocytes and epithelial cells. It is upregulated in fibrotic lung diseases including idiopathic pulmonary fibrosis (IPF) and interstitial pneumonia associated with collagen vascular disease (CVD-IP), and plays an important role in fibrosis in multiple organs. It is also often dysregulated in cancers, and may play a role in angiogenesis, cell proliferation and cell survival.
Molecule SMILES: CC=C(C)C(O)C1(C)C2C(C)=CC(C)=CC2(C)C1C(C)=CC1(C)C2OC(=O)C1(C)C(=O)C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Shimalactone B is a natural product found in Aspergillus stellatus with data available.
Molecule SMILES: COC(=O)C(O)COc1ccc(C2=C(CC(C)C)C(=O)NC2=O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Antrocinnamomin G is a natural product found in Taiwanofungus camphoratus and Antrodia cinnamomea with data available.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1c1ccccc1[N+](=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Nisoldipine is a second generation calcium channel blocker and commonly used antihypertensive agent. Nisoldipine therapy is associated with a low rate of serum enzyme elevations, but has not been specifically linked to instances of clinical apparent acute liver injury.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1c1ccccc1[N+](=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate is a dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris. It is a C-nitro compound, a diester, a dihydropyridine, a methyl ester and a member of dicarboxylic acids and O-substituted derivatives.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1c1ccccc1[N+](=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone or in combination with other agents in the management of hypertension.
Molecule SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)C)C1c1ccccc1[N+](=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Nisoldipine is a Dihydropyridine Calcium Channel Blocker. The mechanism of action of nisoldipine is as a Calcium Channel Antagonist. The physiologic effect of nisoldipine is by means of Decreased Blood Pressure.