IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: C=C1Cc2c(Cl)cc3[nH]c4c5c3c2C2C1CC2C(C)(C)OC5C1CCC2(O)C35OC3C(O)C(C(=C)C)OC5CCC2(C)C41C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 21-Chloro-15,16,33,33-tetramethyl-24-methylidene-10-prop-1-en-2-yl-7,11,32-trioxa-18-azadecacyclo[25.4.2.02,16.05,15.06,8.06,12.017,31.019,30.022,29.025,28]tritriaconta-17(31),19,21,29-tetraene-5,9-diol is a natural product found in Penicillium crustosum and Penicillium solitum with data available.
Molecule SMILES: COc1cccc(S(=O)(=O)NC2CCC(CCn3cc(-c4ccccc4OC)nn3)OC2CO)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-[4-(2-methoxyphenyl)-1-triazolyl]ethyl]-3-oxanyl]-3-methoxybenzenesulfonamide is a C-glycosyl compound.
Molecule SMILES: CCC=CCC=CC=COC=CCCCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: 9-Nona-1,3,6-trienoxynon-8-enoic acid is a natural product found in Solanum tuberosum with data available.
Molecule SMILES: C=CC(C)(CCC=C(C)CCCC(C)CO)OC1OC(COC(C)=O)C(O)C(O)C1OC(C)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(2R,3S,4S,5R,6S)-5-acetyloxy-3,4-dihydroxy-6-[(3S,6E,11R)-12-hydroxy-3,7,11-trimethyldodeca-1,6-dien-3-yl]oxyoxan-2-yl]methyl acetate is a natural product found in Gaillardia aestivalis with data available.
Molecule SMILES: CC1=C2C(CC(C)C3C=CC(=O)C3(C)C2O)OC1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Isohelenalin is a natural product found in Helenium microcephalum with data available.
Molecule SMILES: CC1CC2C(C=CC3CC(O)CC4CC(=O)C(=CC32)C(=O)O4)C1=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (1E,3R,4R,6R,8R,11R,13R,15R)-13-hydroxy-6-methyl-16-oxatetracyclo[13.2.2.03,11.04,8]nonadeca-1,9-diene-7,17,18-trione is a natural product found in Micromonospora chalcea with data available.
Molecule SMILES: CC=C(C)c1ccc(CC(C)C)c(=O)o1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 6-But-2-en-2-yl-3-(2-methylpropyl)pyran-2-one is a natural product found in Nocardiopsis with data available.
Molecule SMILES: CC(=O)OC1C=C(C)C(O)CC=C(C)CCC1C(C)CCC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [4-Hydroxy-3,7-dimethyl-10-(6-methylhept-5-en-2-yl)cyclodeca-2,6-dien-1-yl] acetate is a natural product found in Dictyota coriacea with data available.
Molecule SMILES: OC1CC2(O)NC1CC(O)C2O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Calystegine B1 is a natural product found in Duboisia leichhardtii, Ipomoea hederifolia, and other organisms with data available.
Molecule SMILES: COc1c(O)cc(CC=Cc2ccccc2O)c(OC)c1OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 5-[3-(2-Hydroxyphenyl)prop-2-en-1-yl]-2,3,4-trimethoxyphenol is a natural product found in Machaerium acutifolium with data available.
Molecule SMILES: CCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: PA(14:1(9Z)/20:0) is a 1,2-diacyl-sn-glycerol 3-phosphate.
Molecule SMILES: COC1CCC2(C)C3=C(CCC2C1(C)C)CC1(C)CCC2C(C)(C)C(=O)CCC2(C)C1CC3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (3S,6S,11R,12R,16S,19S,21R)-19-methoxy-3,7,7,11,16,20,20-heptamethylpentacyclo[13.8.0.03,12.06,11.016,21]tricos-1(15)-en-8-one is a natural product found in Picea jezoensis with data available.
Molecule SMILES: CC(C)CCCCCCCCCCCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 13-methyltetradecan-1-ol is a long-chain fatty alcohol that is tetradecan-1-ol bearing a methyl substituent at position 13. It is a long-chain primary fatty alcohol and a fatty alcohol 15:0.
Molecule SMILES: CC(O)C1OC(Oc2c(-c3ccc(O)cc3)oc3cc(C4OC(C(C)OC5OC(C(C)O)C(O)C5O)C(O)C4O)cc(O)c3c2=O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[(1S)-1-hydroxyethyl]oxolan-2-yl]oxy-7-[(2S,3S,4R,5S)-5-[(1R)-1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[(1S)-1-hydroxyethyl]oxolan-2-yl]oxyethyl]-3,4-dihydroxyoxolan-2-yl]-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one is a natural product found in Macroptilium atropurpureum with data available.
Molecule SMILES: O=C1OC2(c3cc(Br)c(O)c(Br)c3Oc3c2cc(Br)c(O)c3Br)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Phloxine O is a xanthene dye that is fluorescein in which the hydrogens at positions 2',4',5' and 7' are replaced by bromo groups, and the hydrogens at positions 4,5,6 and 7 are replaced by chloro groups. It is a red synthetic pigment which is widely used in colored cosmetics (e.g. lipsticks and blushers). It has a role as a fluorescent dye. It is a xanthene dye, a member of 2-benzofurans, a gamma-lactone, an organic heteropentacyclic compound, a polyphenol, an oxaspiro compound, a dibromobenzene and a tetrachlorobenzene. It is functionally related to a fluorescein (lactone form).
Molecule SMILES: O=C(C=Cc1ccc(O)cc1)NCCCCN(CCCNC(=O)C=Cc1ccc(O)cc1)C(=O)C=Cc1ccc(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Di-p-coumaroyl-caffeoylspermidine is a natural product found in Quercus dentata with data available.
Molecule SMILES: CC1(O)C(=O)C2=COC(C=CC=CC(=O)O)CC2=CC1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Phomoeuphorbin A is a natural product found in Phomopsis euphorbiae with data available.
Molecule SMILES: CC=CC=CC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (2Z,4E)-hexa-2,4-dienoic acid is one of four possible geometric isomers of sorbic acid, having cis- and trans-double bonds at positions 2 and 4 respectively.
Molecule SMILES: COc1cc(C2Oc3cc4oc(-c5ccccc5)cc(=O)c4c(O)c3OC2CO)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 2,3-Dihydro-10-hydroxy-3beta-(4-hydroxy-3-methoxyphenyl)-2alpha-(hydroxymethyl)-7-phenyl-9H-pyrano[2,3-g]-1,4-benzodioxin-9-one is a natural product found in Scutellaria prostrata with data available.
Molecule SMILES: CC1CN(C(C)CO)C(=O)Cc2cc(NC(=O)CCN3CCOCC3)ccc2OC1CN(C)C(=O)Nc1ccc(F)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: N-[(2S,3R)-2-[[[(4-fluoroanilino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]-3-(4-morpholinyl)propanamide is an organooxygen compound and an organonitrogen compound. It is functionally related to a beta-amino acid.
Molecule SMILES: CCC=CCC1OC1CC=CCCCCCCCC(=O)OC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Methyl 12,13-epoxy-9,15-octadecadienoate is a fatty acid methyl ester.
Molecule SMILES: COc1ccc2c3c(n(C)c2c1)C(CO)NCC31CN(CC2CCOCC2)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: [(1S)-7-methoxy-9-methyl-1'-(4-oxanylmethyl)-1-spiro[2,3-dihydro-1H-pyrido[3,4-b]indole-4,3'-azetidine]yl]methanol is a harmala alkaloid.
Molecule SMILES: COc1cc(OC)c2c(c1)C(CCCCCCCCCC(CCC(C)=O)OC(C)=O)OC2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: [14-(4,6-dimethoxy-3-oxo-1H-2-benzofuran-1-yl)-2-oxotetradecan-5-yl] acetate is a natural product found in Phanerochaete velutina with data available.
Molecule SMILES: Oc1ccc(C2Oc3c(c(O)cc(O)c3C3c4ccc(O)cc4OC(c4ccc(O)cc4)C3O)CC2O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Calodenine C is a natural product found in Campylospermum flavum, Ochna calodendron, and Cassia abbreviata with data available.
Molecule SMILES: CCC1(O)CC(OC2CC(N(C)C)C(OC3CC(O)C(O)C(C)O3)C(C)O2)c2c(O)c3c(c(O)c2C1C(=O)OC)C(=O)c1cccc(O)c1C3=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: methyl (1R,2R,4S)-4-[(2R,4S,5R,6S)-5-[(2S,4S,5S,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate is a natural product found in Streptomyces violaceus with data available.
Molecule SMILES: O=C(Cc1ccccc1)Oc1c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c(O)c1-c1ccc(O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Ganbajunin E is a natural product found in Thelephora ganbajun and Thelephora aurantiotincta with data available.
Molecule SMILES: C=CC(=O)Cc1c(C)ccc(C)c1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 1-(2,3,6-trimethylphenyl)-3-buten-2-one is an aromatic ketone.
Molecule SMILES: O=C(Nc1cccc(Cl)c1)OCC#CCCl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Barban is a crystalline solid. Water solubility is 11 ppm at 20 °C. Used as a selective herbicide.
Molecule SMILES: O=C(Nc1cccc(Cl)c1)OCC#CCCl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Barban is a carbamate ester that is 4-chlorobut-2-yn-1-yl ester of N-(3-chlorophenyl)carbamic acid. A herbicide, it is no longer approved for use within the European Community. It has a role as a herbicide. It is a carbamate ester, an acetylenic compound and a member of monochlorobenzenes.
Molecule SMILES: O=C(Nc1cccc(Cl)c1)OCC#CCCl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Barban is a carbamate pesticide. Carbamate pesticides are derived from carbamic acid and kill insects in a similar fashion as organophosphate insecticides. They are widely used in homes, gardens and agriculture. The first carbamate, carbaryl, was introduced in 1956 and more of it has been used throughout the world than all other carbamates combined. Because of carbaryl's relatively low mammalian oral and dermal toxicity and broad control spectrum, it has had wide use in lawn and garden settings. Most of the carbamates are extremely toxic to Hymenoptera, and precautions must be taken to avoid exposure to foraging bees or parasitic wasps. Some of the carbamates are translocated within plants, making them an effective systemic treatment. (L795)
Molecule SMILES: CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Fluocinolone acetonide is a fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatment of various skin disorders. It has a role as an anti-inflammatory drug and an antipruritic drug. It is an 11beta-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a cyclic ketal, a glucocorticoid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid, an organic heteropentacyclic compound and a primary alpha-hydroxy ketone.
Molecule SMILES: CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.
Molecule SMILES: CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Fluocinolone acetonide is a Corticosteroid. The mechanism of action of fluocinolone acetonide is as a Corticosteroid Hormone Receptor Agonist.
Molecule SMILES: CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Fluocinolone Acetonide is the acetonide salt form of fluocinolone, a synthetic fluorinated corticosteroid with antiinflammatory, antipruritic and vasoconstrictive properties. Fluocinolone is a glucocorticoid receptor agonist that binds to cytoplasmic glucocorticoid receptors and subsequently translocates to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both are potent mediators of inflammation. Fluocinolone exerts its vasoconstrictive effect through inhibition of nitric oxide synthase, thereby blocking nitric oxide production and effectively diminishing the effect of nitric oxide on vascular smooth muscles leading to reduced blood flow.
Molecule SMILES: CC1OC(OC2CCC3(C)C4C(O)CC5(C)C(C6=CC(=O)OC6)CCC5(O)C4CCC3(O)C2)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Bipindogenin guromethyloside is a natural product found in Erysimum pulchellum with data available.
Molecule SMILES: CCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: N-octane is a colorless liquid with an odor of gasoline. Less dense than water and insoluble in water. Hence floats on water. Produces irritating vapor.
Molecule SMILES: CCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Octane is a straight chain alkane composed of 8 carbon atoms. It has a role as a xenobiotic.
Molecule SMILES: CCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Octane is a natural product found in Castanopsis cuspidata, Thymus longicaulis, and other organisms with data available.
Molecule SMILES: CCCCCCCC

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Octane is an alkane with the chemical formula C8H18. It has 18 isomers. One of the isomers, 2,2,4-trimethylpentane or isooctane, is of major importance, as it has been selected as the 100 point on the octane rating scale, with n-heptane as the zero point. Octane ratings are ratings used to represent the anti-knock performance of petroleum-based fuels (octane is less likely to prematurely combust under pressure than heptane), given as the percentage of 2,2,4-trimethylpentane in an 2,2,4-trimethylpentane / n-heptane mixture that would have the same performance. It is an important constituent of gasoline.
Molecule SMILES: CC(=CC=CC=CCc1cnco1)C(O)C(C)(C)C(N)=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (3S,4Z,6Z,8E)-2,2,4-Trimethyl-3-hydroxy-10-(5-oxazolyl)-4,6,8-decatrieneamide is a natural product found in Streptomyces albus with data available.
Molecule SMILES: O=C(CCC(OC1OC(CO)C(O)C(O)C1O)C(O)c1ccc(O)c(O)c1)c1ccc(O)c(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (4S,5R)-1,5-bis(3,4-dihydroxyphenyl)-5-hydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentan-1-one is a natural product found in Curculigo pilosa with data available.
Molecule SMILES: C=C1C2CCC(C=CC(=O)C(C)(C)CCC(=O)Nc3c(OC4OC(CO)C(O)C(O)C4O)ccc(CO)c3O)(CC2)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (Z)-N-[2-hydroxy-3-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-[(2S)-2-hydroxy-3-methylidene-1-bicyclo[2.2.2]octanyl]-4,4-dimethyl-5-oxohept-6-enamide is a natural product found in Streptomyces platensis with data available.
Molecule SMILES: C=C1Cc2c(Cl)cc3[nH]c4c5c3c2C2C1CC2C(C)(C)OC5C1CCC2(O)C35OC3C(O)C(C(=C)C)OC5CCC2(C)C41C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1S,2R,5S,6R,8S,9R,10R,12R,15S,16R,25R,27S,28S)-21-chloro-15,16,33,33-tetramethyl-24-methylidene-10-prop-1-en-2-yl-7,11,32-trioxa-18-azadecacyclo[25.4.2.02,16.05,15.06,8.06,12.017,31.019,30.022,29.025,28]tritriaconta-17(31),19,21,29-tetraene-5,9-diol is a natural product found in Penicillium crustosum and Penicillium solitum with data available.
Molecule SMILES: COc1cc(O)c2c(c1)cc(C)c1c3c(c(=O)oc12)C=CC(C)(C)O3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Vismiaguianin A is a natural product found in Vismia guianensis with data available.
Molecule SMILES: O=c1cc(O)c2c(O)oc3c(=O)cc(O)c4c(O)oc1c2c43

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 3,5,10,12-Tetrahydroxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),3,5,8(16),10,12-hexaene-7,14-dione is a natural product found in Platycarya strobilacea with data available.
Molecule SMILES: CC(=Cc1ccc(Cl)[nH]1)c1nc(C(O)C(C)C(C)O)co1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Pyrronazol C2 is a natural product found in Nannocystis pusilla with data available.
Molecule SMILES: Cc1nc(-c2cn3c(n2)-c2ccc(-c4cnn(C(C)(C)C(N)=O)c4)cc2OCC3)n(C(C)C)n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Taselisib has been used in trials studying the treatment and basic science of LYMPHOMA, Breast Cancer, Ovarian Cancer, Solid Neoplasm, and HER2/Neu Negative, among others.
Molecule SMILES: Cc1nc(-c2cn3c(n2)-c2ccc(-c4cnn(C(C)(C)C(N)=O)c4)cc2OCC3)n(C(C)C)n1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Taselisib is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity. Taselisib selectively inhibits PIK3CA and its mutant forms in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PIK3CA-expressing tumor cells. By specifically targeting class I PI3K alpha, this agent may be more efficacious and less toxic than pan PI3K inhibitors. Dysregulation of the PI3K/Akt/mTOR pathway is frequently found in solid tumors and causes increased tumor cell growth, survival, and resistance to both chemotherapy and radiotherapy. PIK3CA, which encodes the p110-alpha catalytic subunit of the class I PI3K, is mutated in a variety of cancer cell types and plays a key role in cancer cell growth and invasion.