IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: CC1OC(OC2C(OC3C(OC4CCC5(C)C(CCC6(C)C5CC=C5C7CC(C)(CO)CC(O)C7(C)CCC56C)C4(C)CO)OC(C(=O)O)C(O)C3O)OC(CO)C(O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8aR,9R,11R,12aS,14aR,14bR)-9-hydroxy-4,11-bis(hydroxymethyl)-4,6a,6b,8a,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid is a natural product found in Abrus melanospermus with data available.
Molecule SMILES: CC1(CO)CC2C3=CCC4C5(C)CCC(OC6OC(C(=O)O)C(O)C(O)C6OC6OC(CO)C(O)C(O)C6O)C(C)(CO)C5CCC4(C)C3(C)CCC2(C)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8aR,9S,10R,11R,12aS,14aR,14bR)-9,10-dihydroxy-4,11-bis(hydroxymethyl)-4,6a,6b,8a,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4-dihydroxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid is a natural product found in Pueraria montana var. lobata with data available.
Molecule SMILES: Nc1ccc(S(=O)(=O)Nc2cnc3c(Cl)cccc3n2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer.
Molecule SMILES: Nc1ccc(S(=O)(=O)Nc2cnc3c(Cl)cccc3n2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Chloroquinoxaline Sulfonamide is a chlorinated heterocyclic sulfanilamide with potential antineoplastic activity and potential immunosuppressive activity.  Chloroquinoxaline sulfonamide poisons topoisomerase II alpha and topoisomerase II beta, thereby causing double-stranded breaks in DNA, accumulation of unrepaired DNA, and apoptosis.  This agent also exhibits lymphotoxicity by inhibiting lymphocyte activation in a cell cycle-specific manner. (NCI04)
Molecule SMILES: CC(Nc1nc(-c2ccccc2O)nc2ccccc12)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 6-[4-(1-phenylethylamino)-1H-quinazolin-2-ylidene]-1-cyclohexa-2,4-dienone is a member of quinazolines.
Molecule SMILES: CC(=O)OC1C2C(CC(C)C3C=CC(=O)C31C)OC(=O)C2C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Isotenulin is a sesquiterpene lactone.
Molecule SMILES: C=C(CCC(C)C1CCC2C3=CCC4C(C(=O)[O-])C(O)CCC4(C)C3CCC21C)C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 3beta-hydroxy-5alpha-ergosta-7,24(28)-diene-4alpha-carboxylate is a steroid acid anion resulting from the deprotonation of the carboxy group of 3beta-hydroxy-5alpha-ergosta-7,24(28)-diene-4alpha-carboxylic acid. The major species at pH 7.3. It is a conjugate base of a 3beta-hydroxy-5alpha-ergosta-7,24(28)-diene-4alpha-carboxylic acid.
Molecule SMILES: O=C(CC1CCC2C(COCC(O)CN2C(=O)c2ccc3c(c2)OCO3)O1)NC1CCCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 2-[(3R,6aR,8R,10aR)-1-(1,3-benzodioxole-5-carbonyl)-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocin-8-yl]-N-cyclopentylacetamide is a member of benzodioxoles.
Molecule SMILES: C=CC(=O)Nc1cc(-c2nn(C3CCC(N4CCN(C(C)=O)CC4)CC3)c3ncnc(N)c23)ccc1Oc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: TX1-85-1 is an aromatic ether.
Molecule SMILES: COC(=O)C12CCC(C)(C)CC1C1=CCC3C4(C)CCC(OC(C)=O)C(C)(C)C4CCC3(C)C1(C)CC2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Methyl acetyl oleanolate is a natural product found in Eucalyptus camaldulensis with data available.
Molecule SMILES: CC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide is an aromatic ether.
Molecule SMILES: COc1ccc2c3c(n(C)c2c1)C(CO)N(Cc1ccccc1Cl)CC31CCN(C(=O)CC2CC2)CC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 1-[(1R)-2-[(2-chlorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-9-methyl-1'-spiro[1,3-dihydropyrido[3,4-b]indole-4,4'-piperidine]yl]-2-cyclopropylethanone is a harmala alkaloid.
Molecule SMILES: CC(=O)NC(CO)C(O)C(OC1OC(CO)C(OC2OC(COC3OC(CO)C(O)C(O)C3OC3OC(CO)C(OC4OC(CO)C(O)C(OC5OC(CO)C(O)C(O)C5O)C4O)C(O)C3NC(C)=O)C(O)C(OC3OC(CO)C(OC4OC(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4NC(C)=O)C(O)C3OC3OC(CO)C(OC4OC(CO)C(O)C(OC5OC(CO)C(O)C(O)C5O)C4O)C(O)C3NC(C)=O)C2O)C(O)C1NC(C)=O)C(O)COC1OC(C)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: CID 91848939 is a polysaccharide.
Molecule SMILES: COC1CC(OC2CCC3(C)C(=CCC4(O)C3CC(OC(=O)c3ccccc3)C3(C)C(C(C)=O)CCC43O)C2)OC(C)C1OC1CC(OC)C(OC2CC(OC)C(OC3OC(C)C(O)C(OC)C3O)C(C)O2)C(C)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (17alpha)-3beta-[3-O-Methyl-4-O-[3-O-methyl-4-O-[3-O-methyl-4-O-(3-O-methyl-6-deoxy-beta-D-glucopyranosyl)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]-2,6-dideoxy-beta-D-ribo-hexopyranosyl]-2,6-dideoxy-beta-D-ribo-hexopyranosyloxy]-8,14beta-dihydroxy-12beta-(benzoyloxy)pregna-5-ene-20-one is a natural product found in Araujia sericifera with data available.
Molecule SMILES: COC1CN(C)C(=O)c2ccc(NC(=O)Nc3cc(F)ccc3F)cc2OCC(C)N(C)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 1-(2,5-difluorophenyl)-3-[(5R,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]urea is an azamacrocycle and a lactam.
Molecule SMILES: CC(C)=CCCC1(C)C(CC=C(C)C)CC2(CC=C(C)C)C(=O)C3=C(OC(C)(C)C=C3)C1(C(=O)c1ccccc1)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (1S,9R,11S,12R)-1-benzoyl-4,4,12-trimethyl-9,11-bis(3-methylbut-2-enyl)-12-(4-methylpent-3-enyl)-3-oxatricyclo[7.3.1.02,7]trideca-2(7),5-diene-8,13-dione is a natural product found in Hypericum sampsonii with data available.
Molecule SMILES: CC1C(=O)OC2C1CCC1(C)C(OC3OC(CO)C(O)C(O)C3O)CCC(CO)C21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Sonchuside H is a natural product found in Sonchus asper with data available.
Molecule SMILES: CCN1CC2(COC)CCC(O)C34C5CC6C(OC)CC(OC)(C5C6O)C(O)(C(O)C23)C14

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (1S,2R,3R,4S,5S,6S,8R,9R,10S,13S,16S,17R,18S)-11-ethyl-6,8-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,9,16,18-tetrol is a natural product found in Delphinium nuttallianum with data available.
Molecule SMILES: COC(C=CC(C)CCC=C(C)CC1OC(=O)C(C)=C1O)C(C)(O)CCCc1ccoc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Sarcotin M is a natural product found in Sarcotragus with data available.
Molecule SMILES: COc1cccc2cc3c(c(O)c12)C(C)(O)OC3=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: (3R)-3,4-dihydroxy-5-methoxy-3-methylbenzo[f][2]benzofuran-1-one is a natural product found in Eleutherine bulbosa with data available.
Molecule SMILES: C=C1C(C)C2C(Cc3c[nH]c4ccccc34)NC(=O)C23c2ccc([nH]2)C(=O)C(C)CC(C)CC=CC3C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Armochaetoglobin R is a natural product found in Chaetomium globosum with data available.
Molecule SMILES: O=c1oc(CO)cc2c(O)c(O)cc(O)c12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 3-Hydroxymethyl-5,6,8-trihydroxy isocoumarin is a natural product found in Conoideocrella tenuis with data available.
Molecule SMILES: CC(=O)OC1CC2(C)C3CCC4(C)C(CCC4C(C)C4OC4CC(C)C)C3=CCC2C(OS(=O)(=O)O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Acanthosterol sulfate H is a natural product found in Acanthodendrilla with data available.
Molecule SMILES: CC(=CCCC=C(C)CCC=C(C)CCC(O)C(C)(C)O)CCC=C(C)CCC(O)C(C)(C)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (3S,6E,10E,14E,18E,22R)-2,6,10,15,19,23-hexamethyltetracosa-6,10,14,18-tetraene-2,3,22,23-tetrol is a natural product found in Ekebergia capensis with data available.
Molecule SMILES: CCC(C)C(=O)C12C(=O)C3=C(OC(C)(C)C=C3)C(C)(CC(CC=C(C)C)C1(C)C)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: (1S,9R,11R)-1,4,4,10,10-pentamethyl-9-[(2R)-2-methylbutanoyl]-11-(3-methylbut-2-enyl)-3-oxatricyclo[7.3.1.02,7]trideca-2(7),5-diene-8,13-dione is a natural product found in Hypericum papuanum with data available.
Molecule SMILES: C[N+](C)(C)CC(O)CC(N)=O.[Cl-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (S)-carnitinamide chloride is a carnitinamide chloride. It contains a (S)-carnitinamide. It is an enantiomer of a (R)-carnitinamide chloride.
Molecule SMILES: CC(=O)OC1C=C(C2OC3OC(OC4C5=C(C(=O)OC5)C5(C)CCCC(C)(C)C5C4OC(C)=O)C4=CC(OC(C)=O)C5C(C)(C)CCCC5(C)C43O2)C(O)(C=O)C2(C)CCCC(C)(C)C12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: [(1S,4S,4aS,8aS)-3-[(1S,2S,7S,8S,11S,13S,15S)-11-[[(4S,5S,5aS,9aS)-5-acetyloxy-6,6,9a-trimethyl-1-oxo-4,5,5a,7,8,9-hexahydro-3H-benzo[e][2]benzofuran-4-yl]oxy]-8-acetyloxy-2,6,6-trimethyl-12,14,16-trioxatetracyclo[8.6.0.01,13.02,7]hexadec-9-en-15-yl]-4-formyl-4-hydroxy-4a,8,8-trimethyl-5,6,7,8a-tetrahydro-1H-naphthalen-1-yl] acetate is a natural product found in Cinnamosma fragrans with data available.
Molecule SMILES: CC1(C(=O)O)CCCC2(C)C3CCC4CC3(C=C4CO)CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: 17-Hydroxy-ent-kaur-15-en-19-oic acid is a kaurane diterpenoid.
Molecule SMILES: CC1(C(=O)O)CCCC2(C)C3CCC4CC3(C=C4CO)CCC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 17-Hydroxy-ent-kaur-15-en-19-oic acid is a natural product found in Annona glabra with data available.
Molecule SMILES: COC(CC(O)c1c(O)c(C)cc(C(C)=O)c1O)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (2S,4S)-globoscinic acid is a natural product found in Thomsonaria globosa, Xylaria globosa, and Diderma globosum with data available.
Molecule SMILES: CCCCC(C)CCCO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 4-Methyloctan-1-ol is an aliphatic alcohol.
Molecule SMILES: CCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.[Cl-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Benzododecinium chloride is the organic chloride salt of benzododecinium. It has antiseptic and disinfectant properties, and used as a preservative in eye drop formulations. It has a role as an antiseptic drug, a disinfectant, an antifouling biocide and a surfactant. It is a quaternary ammonium salt and an organic chloride salt. It contains a benzododecinium.
Molecule SMILES: CCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.[Cl-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Euchlorine is a mineral with formula of KNaCu2+3O(S6+O4)3 or KNaCu3O(SO4)3. The IMA symbol is Ecr.
Molecule SMILES: C=C1CCC=C(C)CCC2C1CC2(C)CCC=C(C)CCC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Clavaphyllene is a sesterterpene that is produced by a fungal chimeric terpene synthase, PTTS051. It has a role as a fungal metabolite and an Aspergillus metabolite. It is a sesterterpene, a carbobicyclic compound and a polycyclic olefin.
Molecule SMILES: C=C1CCC=C(C)CCC2C1CC2(C)CCC=C(C)CCC=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Clavaphyllene is a natural product found in Aspergillus clavatus with data available.
Molecule SMILES: O=C1OCC(Cc2cccc(OC3OC(C(=O)O)C(O)C(O)C3O)c2)C1Cc1cccc(O)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Enterolactone 3''-glucuronide is an O-acylcarnitine.
Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCCCC(O)C(O)CO

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: (2R,3S)-heptacosane-1,2,3-triol is a natural product found in Vachellia nilotica with data available.
Molecule SMILES: CCCN(C)CC1Oc2cc(C3=CCCCC3)ccc2S(=O)(=O)N(C(C)CO)CC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: (2R)-2-[(4R,5S)-8-(1-cyclohexenyl)-4-methyl-5-[[methyl(propyl)amino]methyl]-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-2-yl]-1-propanol is an aromatic ether.
Molecule SMILES: CC1C(=O)C2(C)CCC34CC56OC(=O)CC5OC(C)(C)C6CC=C3C(=O)C3(OC5C(OC(=O)C5(C)O)C1C23)O4

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1S,3R,7R,10S,15R,17S,18R,21R,22S,23S,25S,29S)-18-hydroxy-9,9,18,23,25-pentamethyl-4,8,16,20,28-pentaoxaoctacyclo[13.12.1.115,22.01,13.03,7.03,10.017,21.025,29]nonacos-12-ene-5,14,19,24-tetrone is a natural product found in Schisandra grandiflora with data available.
Molecule SMILES: CC1(CO)CC(O)C2(C)CCC3(C)C(=CCC4C5(C)CCC(OC6OCC(O)C(OC7OCC(O)C(O)C7O)C6O)C(C)(CO)C5CCC43C)C2C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: (3b,22a)-12-Oleanene-3,22,24,29-tetrol 3-[arabinosyl-(1->3)-arabinoside] is a triterpenoid.
Molecule SMILES: CC(OC(=O)c1cccnc1)C1(O)CCC2(O)C3(O)CC=C4CC(O)CCC4(C)C3CC(OC(=O)C=Cc3ccccc3)C12C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Gagaminine is a natural product found in Cynanchum wilfordii with data available.
Molecule SMILES: C=C1CC(=CC)C(=O)OC2CCN3CC=C(COC(=O)C1(C)OC(C)=O)C23

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: Seneciphyllinine is a natural product found in Senecio rodriguezii with data available.
Molecule SMILES: O=C1CC(=O)NC(=O)N1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Barbituric acid is a barbiturate, the structure of which is that of perhydropyrimidine substituted at C-2, -4 and -6 by oxo groups. Barbituric acid is the parent compound of barbiturate drugs, although it is not itself pharmacologically active. It has a role as an allergen and a xenobiotic. It is a conjugate acid of a barbiturate, a barbiturate(2-) and a barbiturate(1-).
Molecule SMILES: O=C1CC(=O)NC(=O)N1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Barbiturate is a class of drugs characterized as central nervous system (CNS) depressants. Barbiturate compounds bind to the gamma amino butyric acid (GABA)-A receptor, thereby increasing the influx of chloride ions into the neuron and subsequently causing hyperpolarization, which produces a decrease in neuronal transmission. Other barbiturate effects in the CNS may include modulation of sodium and calcium channels as well as inhibition of glutamate-mediated excitation. Although the effects of barbiturates are seen throughout the CNS, the predominant effect occurs in the midbrain region, the part of the brain associated with arousal. CNS depressive effects associated with this drug class include mild sedation, hypnosis, anesthesia, and coma as well as a decrease in seizure activity.
Molecule SMILES: N=C(N)c1ccc2cc(OC(=O)c3ccc(N=C(N)N)cc3)ccc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Nafamostat is a member of benzoic acids and a member of guanidines.
Molecule SMILES: N=C(N)c1ccc2cc(OC(=O)c3ccc(N=C(N)N)cc3)ccc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing continuous renal replacement therapy due to acute kidney injury.
Molecule SMILES: N=C(N)c1ccc2cc(OC(=O)c3ccc(N=C(N)N)cc3)ccc2c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Nafamostat is a broad-spectrum, synthetic serine protease inhibitor, with anticoagulant, anti-inflammatory, mucus clearing, and potential antiviral activities. Upon administration, nafamostat inhibits the activities of a variety of proteases, including thrombin, plasmin, kallikrein, trypsin, and Cl esterase in the complement system, and factors VIIa, Xa, and XIIa in the coagulation system. Although the mechanism of action of nafamostat is not fully understood, trypsinogen activation in the pancreas is known to be a trigger reaction in the development of pancreatitis. Nafamostat blocks the activation of trypsinogen to trypsin and the inflammatory cascade that follows. Nafamostat may also decrease epithelial sodium channel (ENaC) activity and increase mucus clearance in the airways. ENaC activity is increased in cystic fibrosis. In addition, nafamostat may inhibit the activity of transmembrane protease, serine 2 (TMPRSS2), a host cell serine protease that mediates viral cell entry for influenza virus and coronavirus, thereby inhibiting viral infection and replication.
Molecule SMILES: C=CC(C)(C)C12CC3C(=O)Nc4ccccc4C(=O)N3C1Nc1ccccc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 10-(2-Methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.02,10.04,9.015,20]henicosa-4,6,8,15,17,19-hexaene-13,21-dione is a natural product found in Aspergillus fischeri and Penicilliopsis zonata with data available.
Molecule SMILES: CCC12C3CCN4CCC5(c6ccccc6N(C)C5C(C(=O)OC)(O3)C1O)C42

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: methyl (1R,9R,10S,11S,12R,13R,19R)-12-ethyl-11-hydroxy-8-methyl-20-oxa-8,16-diazahexacyclo[10.6.1.110,13.01,9.02,7.016,19]icosa-2,4,6-triene-10-carboxylate is a natural product found in Catharanthus ovalis with data available.
Molecule SMILES: C=C1CCCC2(C)CC3NC(=O)C(C)=C3CC12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (4aS,8aR,9aS)-3,8a-dimethyl-5-methylidene-1,4,4a,6,7,8,9,9a-octahydrobenzo[f]indol-2-one is a natural product found in Conglomeratusclera coerulea with data available.