IDEA-AI4S/PubChemSFT huggingface dataset:
Molecule SMILES: O=C([O-])C(Cl)(Cl)Cl

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Trichloroacetate is a monocarboxylic acid anion that results from the removal of a proton from the carboxylic acid group of trichloroacetic acid. It is functionally related to an acetate. It is a conjugate base of a trichloroacetic acid.
Molecule SMILES: COC(=O)C1CC(=O)C2CC(=O)OCC21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: methyl (4aR,7S,7aS)-3,5-dioxo-1,4,4a,6,7,7a-hexahydrocyclopenta[c]pyran-7-carboxylate is a natural product found in Torricellia tiliifolia with data available.
Molecule SMILES: CCCCCCCCCCCCCCCC(O)C(N)COC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: Beta-D-galactosyl-(1<->1')-sphinganine is a glycosylsphingoid in which a beta-D-galactosyl residue is attached to the primary hydroxyl group of sphinganine. It is a conjugate base of a beta-D-galactosyl-(1<->1')-sphinganine(1+).
Molecule SMILES: COC1C(=NO)CC2OC1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: CID 10961638 is a natural product found in Streptomyces and Streptomyces longisporoflavus with data available.
Molecule SMILES: O=C(NCCCCc1ccccc1)C12CN(Cc3ccccc3)CC1C(c1ccc([N+](=O)[O-])cc1)=NO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: 3-(4-nitrophenyl)-N-(4-phenylbutyl)-5-(phenylmethyl)-4,6-dihydro-3aH-pyrrolo[3,4-d]isoxazole-6a-carboxamide is an organic amino compound and a member of benzenes.
Molecule SMILES: CCC(C)c1ccc(C(O)C(C)O)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: (1S,2R)-1-[4-[(2S)-butan-2-yl]phenyl]propane-1,2-diol is a natural product found in Pimpinella aurea with data available.
Molecule SMILES: C=CC1(C)CCC2C(C)(O1)C(=O)CC1C(C)(C)C(OC(C)=O)CC(OC(=O)C(C)=CC)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: [(3S,4aR,6aR,8S,10R,10aR,10bS)-8-acetyloxy-3-ethenyl-3,4a,7,7,10a-pentamethyl-5-oxo-1,2,6,6a,8,9,10,10b-octahydrobenzo[f]chromen-10-yl] (Z)-2-methylbut-2-enoate is a natural product found in Leiocarpa semicalva with data available.
Molecule SMILES: CC1NCC23CCC4C(C=CC5=CC(=O)CCC54C)C2CCC13

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: 23-Norcona-4,6-dien-3-one is a natural product found in Holarrhena pubescens with data available.
Molecule SMILES: COc1cccc(-c2ccc3ncnc(NCc4ccc5c(c4)OCO5)c3c2)c1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-4-quinazolinamine is a member of quinazolines.
Molecule SMILES: O=c1c2ccccc2nnn1-c1ccc(Br)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 3-(4-bromophenyl)-1,2,3-benzotriazin-4-one is a member of benzotriazines.
Molecule SMILES: CN1C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2.CN1C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2.O.O=S(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Atropine Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna.  Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation.  This agent may induce tachycardia, inhibit secretions, and relax smooth muscles. (NCI04)
Molecule SMILES: O=C1c2ccccc2C(Cc2ccnc(F)c2)(Cc2ccnc(F)c2)c2ccccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9-anthracenone is a member of anthracenes.
Molecule SMILES: CC(=O)OC1C2C(C)c3ccoc3CC2C2(C)CCCC(C)(C)C2(O)C1OC(=O)C=Cc1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: [(4aR,5R,6R,6aS,7R,11aS,11bR)-6-acetyloxy-4a-hydroxy-4,4,7,11b-tetramethyl-2,3,5,6,6a,7,11,11a-octahydro-1H-naphtho[2,1-f][1]benzofuran-5-yl] (E)-3-phenylprop-2-enoate is a natural product found in Caesalpinia with data available.
Molecule SMILES: Nc1ncnc2c1nc1n2C2CC(O)C(O2)C1OP(=O)(O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: 8,5'-cyclo-2'-deoxyadenosine monophosphate is an organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5' of dAMP. It has a role as a Mycoplasma genitalium metabolite. It is a N-glycosyl compound, a bridged compound, an aromatic amine, an organic heterotetracyclic compound, a phosphate monoester and a secondary alcohol. It is functionally related to a 2'-deoxyadenosine 5'-monophosphate.
Molecule SMILES: COCC1CO1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a description of this molecule <molecule_2d> .

assistant: Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)
Molecule SMILES: CC1(C)c2[nH]c3cc(Cl)ccc3c2CC23C[NH+]4CCCC4(CC21)C(=O)N3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (+)-malbrancheamide B(1+) is an organic molecular entity.
Molecule SMILES: O=C1CC(c2ccc(O)c(O)c2)c2c(cc(O)c3c2OC(c2ccc(O)cc2)C(O)C3)O1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: Corbulain Ia is a natural product found in Smilax corbularia with data available.
Molecule SMILES: C=C(C)C12OC3(c4ccccc4)OC1C1C(O)C(O)(CO)C(O)C4(O)C(=O)C(C)=CC4C1(O3)C(C)C2OC(=O)c1ccccc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1R,2R,6S,7R,8S,9S,10S,11R,13S,15S,16R,17R)-6,7,8,9-tetrahydroxy-8-(hydroxymethyl)-4,17-dimethyl-5-oxo-13-phenyl-15-prop-1-en-2-yl-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadec-3-en-16-yl] benzoate is a natural product found in Daphne genkwa with data available.
Molecule SMILES: CCC(=O)NC(CCSC)C(=O)[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-propanoyl-L-methioninate is an N-(fatty acyl)-L-alpha-amino acid anion that is the conjugate base of N-propanoyl-L-methionine, obtained by deprotonation of the carboxy group; major species at pH 7.3. It is a N-(fatty acyl)-L-alpha-amino acid anion and a N-(fatty acyl)-L-methionine(1-). It is a conjugate base of a N-propanoyl-L-methionine.
Molecule SMILES: CC(C)CCCC=CCCCCCCCC(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (9Z)-14-Methyl-9-pentadecenoic acid is a natural product found in Streptomyces with data available.
Molecule SMILES: COC(Cc1ccc(O)c(O)c1)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 3-(3,4-Dihydroxyphenyl)-2-methoxypropionic acid is a monocarboxylic acid and a member of benzenes.
Molecule SMILES: CC1=CC2OC3CC4OC(=O)C=CCCC56OCCC(=CC(=O)OCC2(CC1)C4(C)C31CO1)C5OC(O)C6O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: (1S,4Z,8R,9S,10S,11R,13R,18R,22E,24R,26R,27R)-26,27-dihydroxy-9,15-dimethylspiro[7,12,20,25,28-pentaoxahexacyclo[21.4.3.18,11.01,24.09,18.013,18]hentriaconta-4,14,22-triene-10,2'-oxirane]-6,21-dione is a natural product found in Paramyrothecium roridum with data available.
Molecule SMILES: CC(=O)NC1C(O)OC(CO)C(OC2OC(CO)C(OC3OC(COC4OC(COC5OC(CO)C(O)C(O)C5OC5OC(CO)C(OC6OC(CO)C(O)C(O)C6O)C(O)C5O)C(O)C(OC5OC(CO)C(O)C(O)C5OC5OC(CO)C(OC6OC(CO)C(O)C(O)C6O)C(O)C5O)C4O)C(O)C(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4O)C3O)C(O)C2NC(C)=O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: CID 91860460 is a polysaccharide.
Molecule SMILES: C=C1C2(C)CC3=C(C)C4(C=CC(=O)OC4(C)C)CCC3(C)C13C(=O)OC(C)C3(O)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Isoaustinone is a natural product found in Melia azedarach with data available.
Molecule SMILES: Oc1ccccc1-c1nc(-c2nc3c(Cl)cccc3c3c(Cl)c[nH]c23)cs1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Pyonitrin D is a natural product found in Pseudomonas protegens with data available.
Molecule SMILES: CC(=O)OCC12C(OC(C)=O)C(OC(C)=O)CC(C)C13CC(C(OC(C)=O)C2OC(=O)c1ccccc1)C(C)(C)O3

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: [(1S,2R,4S,5R,6S,7S,8S,9S)-4,5,8-triacetyloxy-6-(acetyloxymethyl)-2,10,10-trimethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate is a natural product found in Celastrus angulatus with data available.
Molecule SMILES: COc1ccc(C2CC(=O)c3c(cc(O)cc3OC3OC(CO)C(O)C(O)C3O)O2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 7-Hydroxy-2-(4-methoxyphenyl)-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one is a natural product found in Hoppea dichotoma with data available.
Molecule SMILES: COc1cc(C(=O)O)cc(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)c1[O-]

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Provide a brief overview of this molecule <molecule_2d> .

assistant: 3-nonaprenyl-4-hydroxy-5-methoxybenzoate is a 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate in which the polyprenyl chain contains 9 prenyl units; major species at pH 7.3. It is a conjugate base of a 3-nonaprenyl-4-hydroxy-5-methoxybenzoic acid.
Molecule SMILES: COc1ccccc1NC(=O)N1CC2C(c3ccccc31)C(CO)N2Cc1ccc2c(c1)OCO2

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1S,2aR,8bR)-2-(1,3-benzodioxol-5-ylmethyl)-1-(hydroxymethyl)-N-(2-methoxyphenyl)-1,2a,3,8b-tetrahydroazeto[2,3-c]quinoline-4-carboxamide is a member of quinolines.
Molecule SMILES: OCc1ccccc1OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: 2-(Hydroxymethyl)phenyl 2-O-beta-D-glucopyranosyl-6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside is a natural product found in Alangium chinense with data available.
Molecule SMILES: CCNC(=O)C1OC(n2cnc3c(N)nc(C#CCC4CCC(C(=O)OC)CC4)nc32)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Describe this molecule: <molecule_2d> .

assistant: Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies. It is developed by Bristol-Myers Squibb and is in phase II of clinical trials.
Molecule SMILES: CCNC(=O)C1OC(n2cnc3c(N)nc(C#CCC4CCC(C(=O)OC)CC4)nc32)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: ATL146e is an anti-inflammatory compounds which is an agonist of A2A adenosine receptors.
Molecule SMILES: COC1C23NC(=O)C4(CCCN4C2=O)CC3C(C)(C)C12Nc1c(ccc3c1C=CC(C)(C)O3)C2=O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Amoenamide C is a natural product found in Fusarium sambucinum with data available.
Molecule SMILES: CC12CC(c3ccoc3)OC(=O)C1(O)C(O)C1OCC3(OC4OC(CO)C(O)C(O)C4O)C=CCC2C13C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: (1S,2S,4S,7S,8S,9S,12S,16S)-4-(furan-3-yl)-7,8-dihydroxy-2,16-dimethyl-12-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5,10-dioxatetracyclo[7.6.1.02,7.012,16]hexadec-13-en-6-one is a natural product found in Fibraurea tinctoria with data available.
Molecule SMILES: CC1(C)C(=O)CCC2(C)C1CCC1(C)C2CCC2C=CC(O)C21C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: 15alpha-Hydroxymansumbinone is a natural product found in Commiphora kua with data available.
Molecule SMILES: COc1ccc(CNC(=O)CC2CCC(NC(=O)c3cccc(F)c3)C(CO)O2)cc1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: 3-fluoro-N-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]-3-oxanyl]benzamide is a C-glycosyl compound.
Molecule SMILES: CC(=CC(O)CC(C)C1CCC2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3CCC12C)C(=O)O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Abiesatrine G is a natural product found in Abies holophylla with data available.
Molecule SMILES: NC(N)=NCCN1CCCCCCC1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: I'd like a short overview about this molecule <molecule_2d>. Can you do that?

assistant: Guanethidine is a member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group. It has a role as an antihypertensive agent, an adrenergic antagonist and a sympatholytic agent. It is a member of guanidines and a member of azocanes. It is functionally related to a guanidine. It derives from a hydride of an azocane.
Molecule SMILES: O=C1C=C(C=Cc2ccc(O)c(O)c2)OC12C(c1cc3oc(=O)c4cc(O)c(O)cc4c3c(=O)o1)=Cc1cc(O)c(O)cc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Phelligridin G is an organic heterotricyclic compound isolated from the fruiting bodies of the fungus Phellinus igniarius. It has a role as a fungal metabolite. It is an organic heterotricyclic compound, a polyphenol, an oxaspiro compound and a delta-lactone.
Molecule SMILES: O=C1C=C(C=Cc2ccc(O)c(O)c2)OC12C(c1cc3oc(=O)c4cc(O)c(O)cc4c3c(=O)o1)=Cc1cc(O)c(O)cc12

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Phelligridin G is a natural product found in Phellinus igniarius with data available.
Molecule SMILES: COC(=O)C=C(C)C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Methyl 3-methyl-2-butenoate is a natural product found in Carica papaya and Vaccinium angustifolium with data available.
Molecule SMILES: CC1OC(OC2C(O)C(C)OC(OC3C(O)OC(C)C(O)C3O)C2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: Alpha-D-Rhap-(1->3)-alpha-D-Rhap-(1->2)-alpha-D-Rhap is a linear trisaccharide consisting of three alpha-D-rhamose units joined by an alpha-(1->3)- and an alpha-(1->2)- linkage. It has a role as an epitope.
Molecule SMILES: O=C(O)C1OC(Oc2c(O)cc3oc(-c4ccccc4)cc(=O)c3c2O)C(O)C(O)C1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you provide a description of this molecule <molecule_2d> ?

assistant: 6-(5,7-Dihydroxy-4-oxo-2-phenylchromen-6-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid is a natural product found in Scutellaria grossa with data available.
Molecule SMILES: CN1CC2CC3=C(CCC45CC6C(C=C34)C63CCC4(CC67CCC8C9(C)C=NC%10C6CC4CC7C%108CCC9)OC53)C(C)(C2)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Tell me something about this molecule: <molecule_2d>

assistant: (1R,1'S,5S,5'S,8'S,9S,9'S,11'R,14R,14'S,15S,16S,17'R,18'R,19R,21S)-5,5',7-trimethylspiro[20-oxa-7-azaheptacyclo[13.6.1.15,9.01,12.04,11.014,16.016,21]tricosa-4(11),12-diene-19,12'-7-azahexacyclo[9.6.2.01,8.05,17.09,14.014,18]nonadec-6-ene] is a natural product found in Staphisagria macrosperma with data available.
Molecule SMILES: COc1cc(-c2cc(=O)c3c(O)cc(O)c(C4OC(CO)C(O)C(O)C4OC4OC(C)C(O)C(O)C4O)c3o2)ccc1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Scoparin 2''-O-rhamnoside is a natural product found in Passiflora coactilis with data available.
Molecule SMILES: CC(C)=CCCC(C)=CCc1cc2c(=O)c3c(O)cc(O)cc3oc2c(O)c1O

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: 7-(3,7-Dimethylocta-2,6-dienyl)-1,3,5,6-tetrahydroxyxanthen-9-one is a natural product found in Garcinia xanthochymus with data available.
Molecule SMILES: CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: Tamibarotene is a dicarboxylic acid monoamide resulting from the condensation of one of the carboxy groups of terephthalic acid with the amino group of 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine. It has a role as an antineoplastic agent and a retinoic acid receptor alpha/beta agonist. It is a member of tetralins, a retinoid and a dicarboxylic acid monoamide. It is functionally related to a 4-carbamoylbenzoic acid and a terephthalic acid.
Molecule SMILES: CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> The above is a compound. Could you please tell me something about it?

assistant: Tamibarotene is a novel synthetic retinoid for acute promyelocytic leukaemia (APL). Tamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical trials in the United States.
Molecule SMILES: CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Given the molecule <molecule_2d>, what can you tell me about it?

assistant: Tamibarotene is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha/beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL-60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular retinoic acid binding protein (CRABP), tamibarotene may show sustained plasma levels compared to ATRA. In addition, this agent may exhibit a lower toxicity profile than ATRA, in part, due to the lack of affinity for the RAR-gamma receptor, the major retinoic acid receptor in the dermal epithelium.
Molecule SMILES: COC1CN(C)C(=O)c2ccc(NS(C)(=O)=O)cc2OCC(C)NCC1C

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: <molecule_2d> What do you know about the molecule?

assistant: N-[(5R,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide is a lactam and an azamacrocycle.
Molecule SMILES: CC(C)(C)C1CCc2c(sc(NC(=O)c3cc(C4CC4)on3)c2C#N)C1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Please give me some details about this molecule <molecule_2d> .

assistant: N-(6-tert-butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide is an aromatic amide and a heteroarene.
Molecule SMILES: O=C([O-])c1ccccn1

system: You are a chemist. Now you are given a representation of a molecule. Please help me to understand the molecule.

user: Could you give me a brief overview of this molecule <molecule_2d> ?

assistant: Picolinate is a pyridinemonocarboxylate resulting from the removal of a proton from the carboxy group of picolinic acid. It is a conjugate base of a picolinic acid.