Question: When was the final defeat of the Ptolemaic Kingdom?
Sentence: The Hellenistic period may be seen to end either with the final conquest of the Greek heartlands by Rome in 146 BC following the Achean War, with the final defeat of the Ptolemaic Kingdom at the Battle of Actium in 31 BC, or even the move by Roman emperor Constantine the Great of the capital of the Roman Empire to Constantinople in 330 AD.
Answer in sentence: yes