Question: What major interstate runs from Tijuana to Los Angeles?
Sentence: This includes Interstate 5, which runs south to Tijuana and north to Los Angeles; Interstate 8, which runs east to Imperial County and the Arizona Sun Corridor; Interstate 15, which runs northeast through the Inland Empire to Las Vegas and Salt Lake City; and Interstate 805, which splits from I-5 near the Mexican border and rejoins I-5 at Sorrento Valley.
Answer in sentence: yes