Question: What epidemic resulted in numerous deaths between the 1830s and 1860s?
Sentence: All three of these peoples, as well as other indigenous peoples of the Pacific Northwest Coast, experienced smallpox outbreaks from the late 18th through the mid-19th century, with the most devastating epidemics occurring in the 1830s and 1860s, resulting in high fatalities and social disruption.
Answer in sentence: yes