Question: Which work of Isaac Newton was published in Latin and remained inaccessible to readers without education until Enlightenment writers began to translate and analyze it in the vernacular?
Sentence: Sir Isaac Newton's celebrated Philosophiae Naturalis Principia Mathematica was published in Latin and remained inaccessible to readers without education in the classics until Enlightenment writers began to translate and analyze the text in the vernacular.
Answer in sentence: yes