Question: What are the symptoms of EPI?
Answer: Symptoms of exocrine pancreatic insufficiency (EPI) may include

bloating
cramps, discomfort, or pain in theabdomen
diarrhea
loose, greasy, bad-smellingstools
passing excessgas, orflatulence
weight loss

In rare cases, EPI may lead to problems seeing at night or problems with your bones, such as low bone mass or osteoporosis.
Question: What causes EPI?
Answer: Common causes of EPI include

chronicandacutepancreatitis
cystic fibrosis
pancreatic cancer
surgery of the pancreas orupper gastrointestinal tract

Less common causes of EPI include

diabetes—type 1 and type 2
untreatedceliac disease
inflammatory bowel disease, includingCrohn’s diseaseandulcerative colitis
HIV
rare genetic disorders, such asShwachman-Diamond syndromeandJohanson-Blizzard syndrome
Zollinger-Ellison syndrome