HuggingFaceH4/databricks_dolly_15k huggingface dataset:
Instruction: What is the genomics of disease?


Response: With the advent of next-generation sequencing we are obtaining enough sequence data to map the genes of complex diseases including infertility,[31] breast cancer[32] or Alzheimer's disease.[33] Genome-wide association studies are a useful approach to pinpoint the mutations responsible for such complex diseases.[34] Through these studies, thousands of DNA variants have been identified that are associated with similar diseases and traits.[35] Furthermore, the possibility for genes to be used at prognosis, diagnosis or treatment is one of the most essential applications. Many studies are discussing both the promising ways to choose the genes to be used and the problems and pitfalls of using genes to predict disease presence or prognosis.[36]

Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however, these common variants only explain a small fraction of heritability.[37] Rare variants may account for some of the missing heritability.[38] Large-scale whole genome sequencing studies have rapidly sequenced millions of whole genomes, and such studies have identified hundreds of millions of rare variants.[39] Functional annotations predict the effect or function of a genetic variant and help to prioritize rare functional variants, and incorporating these annotations can effectively boost the power of genetic association of rare variants analysis of whole genome sequencing studies.[40] Some tools have been developed to provide all-in-one rare variant association analysis for whole-genome sequencing data, including integration of genotype data and their functional annotations, association analysis, result summary and visualization.[41][42] Meta-analysis of whole genome sequencing studies provides an attractive solution to the problem of collecting large sample sizes for discovering rare variants associated with complex phenotypes.
Instruction: Given this paragraph about battles during India Independence day, what was the date when India win the Independence

Context: August 15, 1947

Response: Independence Day is celebrated annually on 15 August as a public holiday in India commemorating the nation's independence from the United Kingdom on 15 August 1947, the day when the provisions of the Indian Independence Act, which transferred legislative sovereignty to the Indian Constituent Assembly, came into effect. India retained King George VI as head of state until its transition to a republic, when the Constitution of India came into effect on 26 January 1950 (celebrated as Indian Republic Day) and replaced the dominion prefix, Dominion of India, with the enactment of the sovereign law Constitution of India. India attained independence following the independence movement noted for largely non-violent resistance and civil disobedience.
Instruction: What is trekking ? Discuss various types of trekking.


Response: Trekking refers to travel by foot through remote destinations that are in most cases inaccessible and unknown to visitors.Trekking is mainly of four kinds:
1 Easy Trekking: This type of activity if for beginners and basically involves the view of colorful horizons or sight of beautiful nature. 
2 Moderate Trekking: Moderate trekking is more challenging than easy trekking. It is performed on medium to slightly higher altitudes. The individuals doing this type of trekking should be energetic.
3 Strenuous Trekking: This type of trekking requires strenuous physical efforts. It is basically done on high altitude regions and is suitable only for those who have some previous experience of trekking. 
4 Difficult Trekking: Fourth type of trekking is done on steep slopes. Generally professional or experienced trekkers do this type of trekking. This type of trekking requires high level of precision skill and endurance by the trekker.
Instruction: What rhymes with orange?


Response: There is only one perfect rhyming word for orange which is "sporange." A sporange is an old botanical term for "sporangium." The sporangium is the portion of a fern where asexual spores are created.
Instruction: How to add two cells in Excel?


Response: You can use the =cell1 + cell2 operation where cell1 is the first cell and cell2 is the 2nd cell
Instruction: When was Galaga released?

Context: Galaga[a] is a 1981 fixed shooter arcade video game developed and published by Namco. In North America, it was released by Midway Manufacturing. It is the sequel to Galaxian (1979), Namco's first major video game hit in arcades. Controlling a starship, the player is tasked with destroying the Galaga forces in each stage while avoiding enemies and projectiles. Some enemies can capture a player's ship via a tractor beam, which can be rescued to transform the player into a "dual fighter" with additional firepower.

Response: Galaga was released in 1981 as a fixed shooter arcade video game developed and published by Namco.
Instruction: Who is Asa Wood?

Context: Asa Butler Wood (August 26, 1865 - May 7, 1945) was an American politician and newspaper publisher, serving as a state senator in the U.S. state of Nebraska from 1924 to 1930. Born in Wapello County, Iowa. Wood entered the newspaper business as a printer in his teens In 1887, at the age of 21, he founded the Gering Courier, a newspaper he ran until his death in 1945.[1] He was known as "the dean of the newspapermen of the Nebraska Panhandle,” and was at one time president of the Nebraska Press Association. He was also a breeder of cattle, and, like many publishers of that time, the local postmaster.

In 1925, he was elected state senator of Nebraska's Thirty-third District. He served as a Republican senator through 1930, and was known as an advocate of clean government and irrigation policy.

Described as a "walking encyclopedia" of western Nebraska history,he served as president of the Nebraska Historical Society from 1936 to 1938.

He left the Courier to his son, Warren Wood, on his death in 1945.

Response: Born in Iowa, Asa Wood was a politician and newspaper publisher who later served as a state senator of Nebraska.
Instruction: Give me the list of all French president during the fifth Republic


Response: Sure, this is the list of all the French presidents elected during the 5th Republic : 
- Charles De Gaule, from 1959 to 1969, Charles de Gaulle resigned after losing a referendum
- Georges Pompidou, from 1969 to 1974, died of sickness during his presidency,
- Valéry-Giscard d’Estaing, from 1974 to 1981, at this period he was the youngest elected president, 
- François Mitterrand, from 1981 to 1995, he is te first reelected president
- Jacques Chirac, from 1995 to 2007, was reelected with the support of to the "popular front" against the far right, 
- Nicolas Sarkozy, from 2007 to 2012, was known for his conservative stance on law and order issues,
- François Hollande, from 2012 to 2017, was elected on socialist promises, but lied and had run  an ultra-capitalist politic 
- Emmanuel Macron from 2012 to today, the youngest president in the modern era, the first reelected president since the change for the five-year term, french people call him "Jupiter" because he is known for his abuse of power and because he ordered violent repression of demonstrations and strikes.
Instruction: Classify list as breeds of either a 'dog' or a 'cat': Border Collie, Siamese, Maine Coon, German Shepard, Persian, and Corgi?


Response: Border Collie is a breed of dog. Siamese is a breed of cat. Maine Coon is breed of cat. German Shepard is a breed of dog. Persian is a breed of cat. Corgi is breed of dog.
Instruction: How long do I need to work before I retire?


Response: Typically you need to work until the age of 65 before you can retire.  Some jobs may offer you a 401k if you work at the job for an extended period of time which you have access to at the age of 65.  You might be able to retire sooner than the age of 65 if you own your own business, and it makes enough money to support your current lifestyle.  Important things to consider before you retire is whether you have enough money to sustain your lifestyle plus account for yearly inflation, and whether you will want to work part time or do consulting work in retirement to keep yourself busy and give you sense of purpose.
Instruction: What are the 3 branches of science?


Response: Modern Science is mainly constituted of three main branches, i.e. Natural Sciences, Social Sciences, and Formal Sciences as these three areas peruse the nature of our world and the universe most broadly. Thus, the three main branches of Science are:

Natural Sciences
Social Sciences
Formal Sciences
Instruction: What are some items I should stock up on from the grocery store to have in my pantry


Response: canned beans, rice, shelf-stable plant-based milk, crackers, salsa, pasta, pasta sauce, oatmeal, pretzels, maple syrup, noodles, canned tomatoes, tortilla chips, tea, almond butter, walnuts, balsamic vinegar, tahini, dark chocolate, grits, dried cranberries, pistachios
Instruction: Can you recommend best taco places in Austin?


Response: Guero's on S Congress offers great breakfast tacos with reasonable prices and diverse choices. Taco 620 can be hard to spot as it is a food truck located at the corner of FM 620 and FM 2222. But you can’t miss its delicious breakfast tacos. It offers only the classics: egg & potato and egg & cheese. The tacos are fresh, soft and tasty. For more formal choices for lunch or dinner, Cuantos on 12th St and Suerte on 6th St are Mexican restaurants with great seating area and lovely vibes for dating or friends/family gatherings.
Instruction: What is electric current and how is it measured?

Context: The movement of electric charge is known as an electric current, the intensity of which is usually measured in amperes. Current can consist of any moving charged particles; most commonly these are electrons, but any charge in motion constitutes a current. Electric current can flow through some things, electrical conductors, but will not flow through an electrical insulator.
By historical convention, a positive current is defined as having the same direction of flow as any positive charge it contains, or to flow from the most positive part of a circuit to the most negative part. Current defined in this manner is called conventional current. The motion of negatively charged electrons around an electric circuit, one of the most familiar forms of current, is thus deemed positive in the opposite direction to that of the electrons. However, depending on the conditions, an electric current can consist of a flow of charged particles in either direction, or even in both directions at once. The positive-to-negative convention is widely used to simplify this situation.
The process by which electric current passes through a material is termed electrical conduction, and its nature varies with that of the charged particles and the material through which they are travelling. Examples of electric currents include metallic conduction, where electrons flow through a conductor such as metal, and electrolysis, where ions (charged atoms) flow through liquids, or through plasmas such as electrical sparks. While the particles themselves can move quite slowly, sometimes with an average drift velocity only fractions of a millimetre per second, the electric field that drives them itself propagates at close to the speed of light, enabling electrical signals to pass rapidly along wires.
In engineering or household applications, current is often described as being either direct current (DC) or alternating current (AC). These terms refer to how the current varies in time. Direct current, as produced by example from a battery and required by most electronic devices, is a unidirectional flow from the positive part of a circuit to the negative.  If, as is most common, this flow is carried by electrons, they will be travelling in the opposite direction. Alternating current is any current that reverses direction repeatedly; almost always this takes the form of a sine wave. Alternating current thus pulses back and forth within a conductor without the charge moving any net distance over time. The time-averaged value of an alternating current is zero, but it delivers energy in first one direction, and then the reverse. Alternating current is affected by electrical properties that are not observed under steady state direct current, such as inductance and capacitance. These properties however can become important when circuitry is subjected to transients, such as when first energised.

Response: The movement of electric charge is known as an electric current, the intensity of which is usually measured in amperes.
Instruction: Which of these sports involve a ball: swimming, baseball, javelin, hockey, cycling, high jump, tennis, , netball, basketball, and handball.


Response: Hockey, tennis, baseball, basketball, netball, and handball involve a ball. High jump, javelin, swimming, and cycling do not involve a ball.
Instruction: What is a romance language?


Response: Romance languages are a subset of languages derived from Latin roots into fully fledged nationally spoken languages. Examples of Romance languages are French, Italian, Spanish, and Portuguese.
Instruction: What is the PEDALS method


Response: PEDALS is a mnemonic to help in system design interviews, which stands for Process, Estimate, Design, Articulate Data Model, List Architecture and Scale
Instruction: Who are the top 4 in EPL?

Context: The 2000s saw the rise of first Liverpool, and then Arsenal to real competitiveness, Chelsea finally breaking the duopoly by winning in 2004-05. The dominance of the so-called "Top Four" clubs. Arsenal, Chelsea, Liverpool and Manchester United[37][38] saw them finish at the top of the table for the bulk of the decade, thereby guaranteeing qualification for the UEFA Champions League. Only three other clubs managed to qualify for the competition during this period: Newcastle United (2001–02 and 2002–03), Everton (2004–05) and Tottenham Hotspur (2009–10) – each occupying the final Champions League spot, with the exception of Newcastle in the 2002–03 season, who finished third.

Following the 2003–04 season, Arsenal acquired the nickname "The Invincibles" as it became the first, and to date, only club to complete a Premier League campaign without losing a single game.[39][40]

In May 2008, Kevin Keegan stated that "Top Four" dominance threatened the division: "This league is in danger of becoming one of the most boring but great leagues in the world."[41] Premier League chief executive Richard Scudamore said in defence: "There are a lot of different tussles that go on in the Premier League depending on whether you're at the top, in the middle or at the bottom that make it interesting."[42]

Between 2005 and 2012 there was a Premier League representative in seven of the eight Champions League finals, with only "Top Four" clubs reaching that stage. Liverpool (2005), Manchester United (2008) and Chelsea (2012) won the competition during this period, with Arsenal (2006), Liverpool (2007), Chelsea (2008) and Manchester United (2009 and 2011) all losing Champions League finals.[43] Leeds United were the only non-"Top Four" side to reach the semi-finals of the Champions League, in the 2000–01 season. There were three Premier League teams in the Champions League semi-finals in 2006–07, 2007–08, and 2008–09, a feat only ever achieved five times (along with Serie A in 2002–03 and La Liga in 1999–2000).

Additionally, between the 1999–2000 and 2009–10 seasons, four Premier League sides reached UEFA Cup or Europa League finals, with only Liverpool managing to win the competition in 2001. Arsenal (2000), Middlesbrough (2006) and Fulham (2010) all lost their finals.[44]

Although the group's dominance was reduced to a degree after this period with the emergence of Manchester City and Tottenham, in terms of all-time Premier League points won they remain clear by some margin. As of the end of the 2021–22 season – the 27th season of the Premier League – Liverpool, in fourth place in the all-time points table, were over 300 points ahead of the next team, Tottenham Hotspur. They are also the only teams to maintain a winning average of over 50% throughout their entire Premier League tenures.[45]

Response: Arsenal, Liverpool, Manchester United and Chelsea are know as the "Top Four" in the English Premier league.
Instruction: Who is the company Nestle

Context: Nestlé S.A.[a] (/ˈnɛsleɪ, -li, -əl/ NESS-lay, -⁠lee, -⁠əl,[5] French: [nɛsle], German: [ˈnɛstlə] (listen)) is a Swiss multinational food and drink processing conglomerate corporation headquartered in Vevey, Vaud, Switzerland. It is the largest publicly held food company in the world, measured by revenue and other metrics, since 2014.[6][7][8][9][10] It ranked No. 64 on the Fortune Global 500 in 2017[11] and No. 33 in the 2016 edition of the Forbes Global 2000 list of largest public companies.[12]

Response: Nestle S.A. is a Swiss multinational food and drink processing conglomerate corporation headquartered in Vevey, Vaud, Switzerland. It is the largest publicly held food company in the world, measured by revenue and other metrics, since 2014.
Instruction: What is a Japanese dish of prepared rice, usually with some sugar and salt, accompanied by a variety of ingredients, such as seafood, often raw, and vegetables?

Context: Sushi (すし, 寿司, 鮨, 鮓, pronounced [sɯɕiꜜ] or [sɯꜜɕi]) is a Japanese dish of prepared vinegared rice (鮨飯, sushi-meshi), usually with some sugar and salt, accompanied by a variety of ingredients (ねた, neta), such as seafood, often raw, and vegetables. Styles of sushi and its presentation vary widely, but the one key ingredient is "sushi rice", also referred to as shari (しゃり), or sumeshi (酢飯).[1]

The inventor of modern sushi is believed to be Hanaya Yohei, who invented nigiri-zushi, a type of sushi most known today, in which seafood is placed on hand-pressed vinegared rice, around 1824 in the Edo period (1603–1867). It was the fast food of the chōnin class in the Edo period.[2][3][4]

Sushi is traditionally made with medium-grain white rice, though it can be prepared with brown rice or short-grain rice. It is very often prepared with seafood, such as squid, eel, yellowtail, salmon, tuna or imitation crab meat. Many types of sushi are vegetarian. It is often served with pickled ginger (gari), wasabi, and soy sauce. Daikon radish or pickled daikon (takuan) are popular garnishes for the dish.

Sushi is sometimes confused with sashimi, a similar dish in Japanese cuisine that consists of thinly sliced raw fish or occasionally meat.[5]

Response: Sushi is the answer to the question.
Instruction: why do dogs like humans?


Response: As humans we might not understand why dogs are such big fans of us. It could be that from a dogs perspective, humans seem to have an unlimited source of food at their disposal. Dogs may have developed their love for humans just because of all the free food they get from them. Since wolves evolved into dogs because of their symbiotic relationship with humans, one could argue that the domestication of wolves via selective breeding led to the reason most dogs like humans. Dogs also like humans because humans play with them and scratch them behind the ear. It could even be that dogs like humans because of a humans opposable thump, as humans could not throw a ball without them.
Instruction: Why playing Phase 10 make people so angry?


Response: Unlike a similar card game, Uno, players can target one another in a more direct way.  This can cause players to feel singled out and targeted which may feel unfair.  Skip cards can be given to anyone which means that everyone can skip the same person if they wanted to or make someone draw card after card until they are so far behind there is no reason for them to continue to play the game.  This can be frustrating and cause players to lash out.
Instruction: What are some necessary equipment for camping?


Response: The equipment needed for camping can vary considerably depending on the kind of camping one is planning on doing. Here are some things that are commonly needed for camping comfortably:
1. A shelter, like a tent.
2. Sleeping bag
3. Sleeping pad or mattress
4. Camp lights
5. Camp kitchen utensils
6. A stove
7. Cutlery
8. Firewood
9. Clean drinking water, or water filters
10. A camp cooler
Instruction: Which DJ Introduced BeatBullyz on the BBC Introducting stage?

Context: Since their formation, the Beatbullyz have had a busy career performing at local venues in Swindon. In 2008, they came 1st in Channel 4's unsigned band competition, which won them a chance to star in the soap opera Hollyoaks. In the same year, they released their album Rootz. In 2009, they got their break in the form of Radio 1's Big Weekend in Swindon, where they appeared on the "BBC Introducing" stage, introduced by Radio 1 DJ Huw Stephens. He invited them back for the Maida Vale Session in July. In August that year, they performed at the Moonfest as well as supporting Example in the later part of 2009.

In February 2010, they shared a stage with Scouting for Girls and backed N Dubz on their tour throughout March into April. Dappy from N Dubz said "Beatbullyz are too unique, I love them, no-one sounds like them, Beatbullyz all the way man."[4] They played their own gigs throughout April, including a performance at the Playaway Festival. The next month they were back at Radio 1's Big Weekend in Wales where Fearne Cotten introduced them, pledging her support when they headlined the BBC Introducing stage. They released their debut single Skillz that May.

In 2010 they shared a stage with Eliza Doolittle and performed at the Wireless Festival in July. They unveiled their second release, Bounce and then their third release Human Nature and the last release single Heartbeat Ft Lizzy Paterson.Beatbullyz played at the Big Arts Day in Swindon at Lydiard Park. They carried on touring, sharing the stage with such acts as Professor Green and Tinchy Stryder at Spa Bidlington. They recorded a track with, Lizzie Patterson, sister of Robert Patterson, in 2010. In August, they supported Jason Derulo on his UK tour as well as doing their own tour ending in February 2011. In September 2010, Beatbullyz released their album Human Nature and throughout December supported JLS on their tour across the UK in 2010. They supported Example in their hometown Swindon at the MECA. Bozo is featured on a track with another local from Swindon, Daine Gooden. In May 2011 they supported Coolio.

Response: DJ Huw Stephens introduced BeatBullyz on the BBC Introducing stage on Radio 1.
Instruction: How many disciplines of rowing are there?

Context: Rowing, sometimes called crew in the United States, is the sport of racing boats using oars. It differs from paddling sports in that rowing oars are attached to the boat using oarlocks, while paddles are not connected to the boat. Rowing is divided into two disciplines: sculling and sweep rowing. In sculling, each rower holds two oars—one in each hand, while in sweep rowing each rower holds one oar with both hands. There are several boat classes in which athletes may compete, ranging from single sculls, occupied by one person, to shells with eight rowers and a coxswain, called eights. There are a wide variety of course types and formats of racing, but most elite and championship level racing is conducted on calm water courses 2 kilometres (1.2 mi) long with several lanes marked using buoys.

Response: There are two primary rowing disciplines: sweep rowing and sculling.
Instruction: Classify each as of the following as physical or digital: pencil, pen, paper, email, social media, pavers, gutters, cryptocurrency


Response: Pencil: Physical
Pen: Physical
Paper: Physical
Email: Digital
Social Media: Digital
Pavers: Physical
Gutters: Physical
Cryptocurrency: Digital