Model: potsu-potsu/bge-base-biomedical-matryoshka-v2
Author: potsu-potsu
Pipeline: sentence-similarity
Library: sentence-transformers
Tags: sentence-transformers, safetensors, bert, sentence-similarity, feature-extraction, generated_from_trainer, dataset_size:4012, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss, en, arxiv:1908.10084, arxiv:2205.13147, arxiv:1705.00652, base_model:BAAI/bge-base-en-v1.5, base_model:finetune:BAAI/bge-base-en-v1.5, license:apache-2.0, model-index, text-embeddings-inference, endpoints_compatible, region:us
Base models (finetune): id: BAAI/bge-base-en-v1.5
Card metadata: language: en
license: apache-2.0
tags: sentence-transformers, sentence-similarity, feature-extraction, generated_from_trainer, dataset_size:4012, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss
base_model: BAAI/bge-base-en-v1.5
widget: source_sentence: Do cephalopods use RNA editing less frequently than other species?
sentences: Extensive messenger RNA editing generates transcript and protein diversity in genes involved in neural excitability, as previously described, as well as in genes participating in a broad range of other cellular functions. , GV1001 is a 16-amino-acid vaccine peptide derived from the human telomerase reverse transcriptase sequence. It has been developed as a vaccine against various cancers., Using acetyl-specific K516 antibodies, we show that acetylation of endogenous S6K1 at this site is potently induced upon growth factor stimulation. We propose that K516 acetylation may serve to modulate important kinase-independent functions of S6K1 in response to growth factor signalling. Following mitogen stimulation, S6Ks interact with the p300 and p300/CBP-associated factor (PCAF) acetyltransferases. S6Ks can be acetylated by p300 and PCAF in vitro and S6K acetylation is detected in cells expressing p300, source_sentence: Can pets affect infant microbiomed?
sentences: Yes, exposure to household furry pets influences the gut microbiota of infants., Thiazovivin is a selective small molecule that directly targets Rho-associated kinase (ROCK) and increases expression of pluripotency factors.,  Here, we present evidence that the calcium/calmodulin-dependent protein kinase IV (CaMK4) is increased and required during Th17 cell differentiation. Inhibition of CaMK4 reduced Il17 transcription through decreased activation of the cAMP response element modulator a (CREM-a) and reduced activation of the AKT/mTOR pathway, which is known to enhance Th17 differentiation. CAMK4 knockdown and kinase-dead mutant inhibited crocin-mediated HO-1 expression, Nrf2 activation, and phosphorylation of Akt, indicating that HO-1 expression is mediated by CAMK4 and that Akt is a downstream mediator of CAMK4 in crocin signaling, source_sentence: In what proportion of children with heart failure has Enalapril been shown to be safe and effective?
sentences: 5-HT2A (5-hydroxytryptamine type 2a) receptor can be evaluated with the [18F]altanserin., In children with heart failure evidence of the effect of enalapril is empirical. Enalapril was clinically safe and effective in 50% to 80% of for children with cardiac failure secondary to congenital heart malformations before and after cardiac surgery,  impaired ventricular function , valvar regurgitation,  congestive cardiomyopathy,  , arterial hypertension, life-threatening arrhythmias coexisting with circulatory insufficiency.   
ACE inhibitors have shown a transient beneficial effect on heart failure due to anticancer drugs and possibly a beneficial effect in muscular dystrophy-associated cardiomyopathy, which deserves further studies., necroptosis
apoptosis  
pro-survival/inflammation NF-κB activation, source_sentence: How are SAHFS created?
sentences: In particular, up to 17% of neutrophil nuclei of healthy women exhibit a drumstick-shaped appendage that contains the inactive X chromosome., miR-1, miR-133, miR-208a, miR-206, miR-494, miR-146a, miR-222, miR-21, miR-221, miR-20a, miR-133a, miR-133b, miR-23, miR-107 and miR-181 are involved in exercise adaptation, Cellular senescence-associated heterochromatic foci (SAHFS) are a novel type of chromatin condensation involving alterations of linker histone H1 and linker DNA-binding proteins. SAHFS can be formed by a variety of cell types, but their mechanism of action remains unclear., source_sentence: What are the effects of the deletion of all three Pcdh clusters (tricluster deletion) in mice?
sentences: Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly. The vertebrate clustered protocadherin (Pcdh) cell surface proteins are encoded by three closely linked gene clusters (Pcdhα, Pcdhβ, and Pcdhγ). Although deletion of individual Pcdh clusters had subtle phenotypic consequences, the loss of all three clusters (tricluster deletion) led to a severe axonal arborization defect and loss of self-avoidance., The myocyte enhancer factor-2 (MEF2) proteins are MADS-box transcription factors that are essential for differentiation of all muscle lineages but their mechanisms of action remain largely undefined. MEF2C expression initiates cardiomyogenesis, resulting in the up-regulation of Brachyury T, bone morphogenetic protein-4, Nkx2-5, GATA-4, cardiac alpha-actin, and myosin heavy chain expression. Inactivation of the MEF2C gene causes cardiac developmental arrest and severe downregulation of a number of cardiac markers including atrial natriuretic factor (ANF). BMP-2, a regulator of cardiac development during embryogenesis, was shown to increase PI 3-kinase activity in cardiac precursor cells, resulting in increased expression of sarcomeric myosin heavy chain (MHC) and MEF-2A. Furthermore, expression of MEF-2A increased MHC expression in a PI 3-kinase-dependent manner. Other studies showed that Gli2 and MEF2C proteins form a complex, capable of synergizing on cardiomyogenesis-related promoters. Dominant interference of calcineurin/mAKAP binding blunts the increase in MEF2 transcriptional activity seen during myoblast differentiation, as well as the expression of endogenous MEF2-target genes. These findings show that MEF-2 can direct early stages of cell differentiation into a cardiomyogenic pathway., Investigators proposed that there have been three extended periods in the evolution of gene regulatory elements. Early vertebrate evolution was characterized by regulatory gains near transcription factors and developmental genes, but this trend was replaced by innovations near extracellular signaling genes, and then innovations near posttranslational protein modifiers.
pipeline_tag: sentence-similarity
library_name: sentence-transformers
metrics: cosine_accuracy@1, cosine_accuracy@3, cosine_accuracy@5, cosine_accuracy@10, cosine_precision@1, cosine_precision@3, cosine_precision@5, cosine_precision@10, cosine_recall@1, cosine_recall@3, cosine_recall@5, cosine_recall@10, cosine_ndcg@10, cosine_mrr@10, cosine_map@100
model-index: name: BGE Base Biomedical MRL
results: task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 768
type: dim_768
metrics: type: cosine_accuracy@1
value: 0.7199434229137199
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8486562942008486
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8811881188118812
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9108910891089109
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7199434229137199
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5836869401225837
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5035360678925035
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.38981612446958985
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.22554410607429126
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3824154392376512
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.46756439563638896
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5895095542551549
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6739349182815118
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7897128488359042
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.6022305135338147
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 512
type: dim_512
metrics: type: cosine_accuracy@1
value: 0.7199434229137199
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8415841584158416
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8783592644978784
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9137199434229137
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7199434229137199
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5770862800565771
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.499009900990099
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.38925035360678933
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.22401966791618977
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.37977753347724374
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.463420179473985
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.590381190671435
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6716911399005047
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7864057834354863
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.5974300704714075
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 256
type: dim_256
metrics: type: cosine_accuracy@1
value: 0.7199434229137199
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8345120226308345
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8684582743988685
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9052333804809052
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7199434229137199
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5671852899575672
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.4908062234794908
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.38316831683168323
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.2250823605276801
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3696119634197729
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.45400696903445054
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5766702213918966
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6613719423604375
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7821041287802251
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.5849638049690181
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 128
type: dim_128
metrics: type: cosine_accuracy@1
value: 0.7043847241867044
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8076379066478077
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8514851485148515
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.8868458274398868
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7043847241867044
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.551155115511551
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.46760961810466767
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3642149929278642
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.21677975114204817
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.35590880436570016
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.43016114067886363
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5438589162837044
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6335084976027522
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7664309288071665
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.5528011599418241
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 64
type: dim_64
metrics: type: cosine_accuracy@1
value: 0.6534653465346535
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.7807637906647807
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8231966053748232
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.8613861386138614
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.6534653465346535
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5176803394625177
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.43790664780763794
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3335219236209335
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.19651385310343594
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3309033023266673
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.3971277800130864
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.49980169940661
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.5831585353912714
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7249141240654673
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.4959257758215307
name: Cosine Map@100
verified: no
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Created: 2025-06-09 07:49:00