Model: sahithkumar7/mpnet-base-matryoshka-iter02
Author: sahithkumar7
Pipeline: sentence-similarity
Library: sentence-transformers
Tags: sentence-transformers, safetensors, mpnet, sentence-similarity, feature-extraction, dense, generated_from_trainer, dataset_size:80, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss, arxiv:1908.10084, arxiv:2205.13147, arxiv:1705.00652, base_model:microsoft/mpnet-base, base_model:finetune:microsoft/mpnet-base, model-index, endpoints_compatible, region:us
Base models (finetune): id: microsoft/mpnet-base
Card metadata: tags: sentence-transformers, sentence-similarity, feature-extraction, dense, generated_from_trainer, dataset_size:80, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss
base_model: microsoft/mpnet-base
widget: source_sentence: How many different active substances were detected in surface water across all catchment areas?
sentences: metabolites were not detected in the water bodies.
2.1.1. Antibiotics/Enzyme-Inhibitors and
Abacavir in Surface-Water
Fifty detections were found in all catchment areas in surface water, which corresponds to 15 different active substances:
12 antibiotics, two enzyme inhibitors, and one antiviral. The number of detections per sampling station ranged from 0 to 7
different active substances. The Ave river-Prazins (Santo Tirso) and Serzedelo I and II (Guimar ã es) as well as Ria
Formosa-coastal water (Faro and Olh ã o), each one with two sampling sites, showed the most detected compounds in, 2. Results
2.1. Frequency of Detections:
Antibiotics/Enzyme-Inhibitors and Abacavir
in Surface-Groundwater
During the screening framework beyond the antibiotics/enzyme-inhibitors, the antiviral abacavir was detected. Therefore,
given the relevance of this compound, it was included in the present study. Although enzyme inhibitors belong to the
antibiotic group, their specific pharmacological properties and detection were sorted apart. In the present study, antibiotic
metabolites were not detected in the water bodies.
2.1.1. Antibiotics/Enzyme-Inhibitors and
Abacavir in Surface-Water, surface water. The relatively higher detection of substances downstream of the effluent discharge points compared with a
low detection in upstream samples could be attributed to the low efficiency in urban wastewater treatment plants or
agricultural pressure. The environmental impact is more critical due to active substances in drinking water or premix
medicated feeds in the veterinary site.
Furthermore, the detection of substances of exclusive human use (abacavir, tazobactam and cilastatin) prove the weak, source_sentence: What group of pharmaceuticals was sulfamethazine matched to when its quantity was missing?
sentences: ciprofloxacin
43%
(3/7), enrofloxacin, norfloxacin, trimethoprim, lincomycin (29% (2/7), abacavir and tetracycline
14% (1/7). The enzyme inhibitors, namely clavulanic acid and cilastatin, were detected once in an urban region located
well. This catchment point showed the most significant
number of pharmaceuticals. West/Tejo and Centre were the regions with the most considerable number of substances in
groundwater, accounting for 43%. All groundwater
samples were contaminated by at least one antibiotic. Supplemental Tables S2 and S4 contain a detailed description of
the, clarithromycin) were the only ones that demonstrated the potential to concentrate in living organisms (log Kow ≥ 3) [14].
All the remaining antibiotics showed a relatively low log Kow and were expected to be present mainly in surface water.
However, the soil mobility/adsorption detected The detected pharmaceuticals showed high to moderate water solubility
and are small ionisable molecules (MW ≤ 900 g/mol). Regarding the octanol/water partitioning coefficient (log Kow) data,, missing quantity for sulfamethazine, the sulfonamides group has been matched.
Consumption (Kg) of the detected pharmaceuticals in Portugal (2017).
1 Amount from ESVAC Report-2017; 2 Match the sulfonamides amount; NA-not available.
Amount of detected pharmaceuticals consumption per Portuguese region. Amount of detected pharmaceuticals
consumption per Portuguese region., source_sentence: What directive sets environmental quality standards for substances in surface waters?
sentences: As much as the specificities of each member state should be considered this issue has become one of the European
community's main concerns [8].
The strategies against water pollution are provided in the Water Framework Directive [9] and the Directive on
Environmental Quality Standards that set environmental quality standards (EQS) for the substances in surface waters
and confirm their designation as priority or priority hazardous substances [10]. Evidence of potential impacts and, seems to undertake a similar fate in the environment.
Nevertheless, due to stronger adsorption, with higher emergence in sediment, its occurrence in the surface water is lower
[71]. The use of tetracyclines, mainly as medicated premix and oral solution for food-producing animals [72], and the very
low bioavailability (e.g. in pig feed) [43] contribute to increasing its release into the environment. Regarding macrolides,
erythromycin and clarithromycin exhibit a remarkable frequency of detection in surface water samples. The most, low flows; otherwise, POCIS might be damage. In ground-waters was used one POCIS unit/well. Due to the high sorption
capacity, POCIS was deployed approximately for 30 days, allowing the polar organic compounds adsorbed to be in the
equilibrium stage with the active substances in an aqueous medium. In the laboratory, POCIS disks were frozen until
extraction.
4.2.2. Qualitative Analysis Method Used
for the Characterisation of Antibiotics in
Surface-Groundwater, source_sentence: What is the molecular weight range of the detected pharmaceuticals?
sentences: 2.3. Physicochemical Properties and Key Pharmacokinetic Features of Detected Pharmaceuticals 2.3. Physicochemical
Properties and Key Pharmacokinetic Features of Detected Pharmaceuticals
The detected pharmaceuticals showed high to moderate water solubility and are small ionisable molecules (MW ≤ 900
g/mol). Regarding the octanol/water partitioning coefficient (log Kow) data, macrolide antibiotics (azithromycin and
clarithromycin) were the only ones that demonstrated the potential to concentrate in living organisms (log Kow ≥ 3) [14]., As much as the specificities of each member state should be considered this issue has become one of the European
community's main concerns [8].
The strategies against water pollution are provided in the Water Framework Directive [9] and the Directive on
Environmental Quality Standards that set environmental quality standards (EQS) for the substances in surface waters
and confirm their designation as priority or priority hazardous substances [10]. Evidence of potential impacts and, passive samplers in groundwater considered the well technical features; the depth and groundwater level were previously
determined since they should be detected at the superficial levels. The passive sampler was placed using a water level
meter, 2 m below the groundwater level. The sampler always remained immersed in water, avoiding extractions and the
regional lowering of the water table [104]. For the sampling stations, sites of different environmental pressures were
considered, specifically urban, agricultural area/animal production, and aquaculture. The information regarding the, source_sentence: What was the most frequently identified pharmaceutical in the groundwater samples?
sentences: Pharmacokinetic characteristics may represent key features in understanding antibiotics occurrence [62]. Most antibiotics
are not completely metabolised in humans and animals; thus, a high percentage of the active substance (40-90%) is
excreted in urine/faeces in the unchanged form. These molecules are discharged into water and soil through wastewater,
animal manure, and sewage sludge, frequently used as fertilisers to agricultural lands. Also, it is expected that the
hospital effluent will contribute partly to the pharmaceutical load in the wastewater treatment plant influence [63]., many domestic and livestock animals. Several formulations of powder for administration in drinking water and medicated
premix are available for poultry and pigs. The excretion of amoxicillin is predominantly renal; more than 80% of the parent
drug is recovered unchanged in the urine. While bioavailability of 75 to 80% is reported in humans, a low value (~30%)
was observed in pigs, calves, foals, and pigeons [26,52]. Maybe this last group of animals contribute more sharply to the, from one to five compounds. The most frequently identified pharmaceuticals, in decreasing order, were ciprofloxacin 43%
(3/7), enrofloxacin, norfloxacin, trimethoprim, lincomycin (29% (2/7), abacavir and tetracycline 14% (1/7). The enzyme
inhibitors, namely clavulanic acid and cilastatin, were detected once in an urban region located well. This catchment point
showed the most significant number of pharmaceuticals. West/Tejo and Centre were the regions with the most
considerable number of substances in groundwater, accounting for 43%. All groundwater samples were contaminated by
pipeline_tag: sentence-similarity
library_name: sentence-transformers
metrics: cosine_accuracy
model-index: name: SentenceTransformer based on microsoft/mpnet-base
results: task: type: triplet
name: Triplet
dataset: name: initial test
type: initial_test
metrics: type: cosine_accuracy
value: 0.7799999713897705
name: Cosine Accuracy
verified: no, task: type: triplet
name: Triplet
dataset: name: final test
type: final_test
metrics: type: cosine_accuracy
value: 0.8199999928474426
name: Cosine Accuracy
verified: no, type: cosine_accuracy
value: 0.8999999761581421
name: Cosine Accuracy
verified: no, type: cosine_accuracy
value: 0.8999999761581421
name: Cosine Accuracy
verified: no, type: cosine_accuracy
value: 0.9200000166893005
name: Cosine Accuracy
verified: no
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Created: 2025-07-18 02:43:25