Model: potsu-potsu/bge-base-biomedical-matryoshka-v3
Author: potsu-potsu
Pipeline: sentence-similarity
Library: sentence-transformers
Tags: sentence-transformers, safetensors, bert, sentence-similarity, feature-extraction, generated_from_trainer, dataset_size:4012, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss, en, arxiv:1908.10084, arxiv:2205.13147, arxiv:1705.00652, base_model:BAAI/bge-base-en-v1.5, base_model:finetune:BAAI/bge-base-en-v1.5, license:apache-2.0, model-index, text-embeddings-inference, endpoints_compatible, region:us
Base models (finetune): id: BAAI/bge-base-en-v1.5
Card metadata: language: en
license: apache-2.0
tags: sentence-transformers, sentence-similarity, feature-extraction, generated_from_trainer, dataset_size:4012, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss
base_model: BAAI/bge-base-en-v1.5
widget: source_sentence: Do cephalopods use RNA editing less frequently than other species?
sentences: Extensive messenger RNA editing generates transcript and protein diversity in genes involved in neural excitability, as previously described, as well as in genes participating in a broad range of other cellular functions. , GV1001 is a 16-amino-acid vaccine peptide derived from the human telomerase reverse transcriptase sequence. It has been developed as a vaccine against various cancers., Using acetyl-specific K516 antibodies, we show that acetylation of endogenous S6K1 at this site is potently induced upon growth factor stimulation. We propose that K516 acetylation may serve to modulate important kinase-independent functions of S6K1 in response to growth factor signalling. Following mitogen stimulation, S6Ks interact with the p300 and p300/CBP-associated factor (PCAF) acetyltransferases. S6Ks can be acetylated by p300 and PCAF in vitro and S6K acetylation is detected in cells expressing p300, source_sentence: Can pets affect infant microbiomed?
sentences: Yes, exposure to household furry pets influences the gut microbiota of infants., Thiazovivin is a selective small molecule that directly targets Rho-associated kinase (ROCK) and increases expression of pluripotency factors.,  Here, we present evidence that the calcium/calmodulin-dependent protein kinase IV (CaMK4) is increased and required during Th17 cell differentiation. Inhibition of CaMK4 reduced Il17 transcription through decreased activation of the cAMP response element modulator a (CREM-a) and reduced activation of the AKT/mTOR pathway, which is known to enhance Th17 differentiation. CAMK4 knockdown and kinase-dead mutant inhibited crocin-mediated HO-1 expression, Nrf2 activation, and phosphorylation of Akt, indicating that HO-1 expression is mediated by CAMK4 and that Akt is a downstream mediator of CAMK4 in crocin signaling, source_sentence: In what proportion of children with heart failure has Enalapril been shown to be safe and effective?
sentences: 5-HT2A (5-hydroxytryptamine type 2a) receptor can be evaluated with the [18F]altanserin., In children with heart failure evidence of the effect of enalapril is empirical. Enalapril was clinically safe and effective in 50% to 80% of for children with cardiac failure secondary to congenital heart malformations before and after cardiac surgery,  impaired ventricular function , valvar regurgitation,  congestive cardiomyopathy,  , arterial hypertension, life-threatening arrhythmias coexisting with circulatory insufficiency.   
ACE inhibitors have shown a transient beneficial effect on heart failure due to anticancer drugs and possibly a beneficial effect in muscular dystrophy-associated cardiomyopathy, which deserves further studies., necroptosis
apoptosis  
pro-survival/inflammation NF-κB activation, source_sentence: How are SAHFS created?
sentences: In particular, up to 17% of neutrophil nuclei of healthy women exhibit a drumstick-shaped appendage that contains the inactive X chromosome., miR-1, miR-133, miR-208a, miR-206, miR-494, miR-146a, miR-222, miR-21, miR-221, miR-20a, miR-133a, miR-133b, miR-23, miR-107 and miR-181 are involved in exercise adaptation, Cellular senescence-associated heterochromatic foci (SAHFS) are a novel type of chromatin condensation involving alterations of linker histone H1 and linker DNA-binding proteins. SAHFS can be formed by a variety of cell types, but their mechanism of action remains unclear., source_sentence: What are the effects of the deletion of all three Pcdh clusters (tricluster deletion) in mice?
sentences: Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly. The vertebrate clustered protocadherin (Pcdh) cell surface proteins are encoded by three closely linked gene clusters (Pcdhα, Pcdhβ, and Pcdhγ). Although deletion of individual Pcdh clusters had subtle phenotypic consequences, the loss of all three clusters (tricluster deletion) led to a severe axonal arborization defect and loss of self-avoidance., The myocyte enhancer factor-2 (MEF2) proteins are MADS-box transcription factors that are essential for differentiation of all muscle lineages but their mechanisms of action remain largely undefined. MEF2C expression initiates cardiomyogenesis, resulting in the up-regulation of Brachyury T, bone morphogenetic protein-4, Nkx2-5, GATA-4, cardiac alpha-actin, and myosin heavy chain expression. Inactivation of the MEF2C gene causes cardiac developmental arrest and severe downregulation of a number of cardiac markers including atrial natriuretic factor (ANF). BMP-2, a regulator of cardiac development during embryogenesis, was shown to increase PI 3-kinase activity in cardiac precursor cells, resulting in increased expression of sarcomeric myosin heavy chain (MHC) and MEF-2A. Furthermore, expression of MEF-2A increased MHC expression in a PI 3-kinase-dependent manner. Other studies showed that Gli2 and MEF2C proteins form a complex, capable of synergizing on cardiomyogenesis-related promoters. Dominant interference of calcineurin/mAKAP binding blunts the increase in MEF2 transcriptional activity seen during myoblast differentiation, as well as the expression of endogenous MEF2-target genes. These findings show that MEF-2 can direct early stages of cell differentiation into a cardiomyogenic pathway., Investigators proposed that there have been three extended periods in the evolution of gene regulatory elements. Early vertebrate evolution was characterized by regulatory gains near transcription factors and developmental genes, but this trend was replaced by innovations near extracellular signaling genes, and then innovations near posttranslational protein modifiers.
pipeline_tag: sentence-similarity
library_name: sentence-transformers
metrics: cosine_accuracy@1, cosine_accuracy@3, cosine_accuracy@5, cosine_accuracy@10, cosine_precision@1, cosine_precision@3, cosine_precision@5, cosine_precision@10, cosine_recall@1, cosine_recall@3, cosine_recall@5, cosine_recall@10, cosine_ndcg@10, cosine_mrr@10, cosine_map@100
model-index: name: BGE Base Biomedical MRL
results: task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 768
type: dim_768
metrics: type: cosine_accuracy@1
value: 0.7496463932107497
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8628005657708628
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8939179632248939
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9222065063649222
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7496463932107497
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5954738330975955
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5182461103253183
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.398019801980198
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.23552722432104642
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.39300580916997035
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.48398991185606194
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.6052039036843697
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6931833007940934
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.811447318201208
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.623648332544624
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 512
type: dim_512
metrics: type: cosine_accuracy@1
value: 0.751060820367751
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8514851485148515
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8896746817538896
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9207920792079208
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.751060820367751
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.594059405940594
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5123055162659123
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3953323903818953
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.23603995416545945
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.38986102707862896
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.4768134287558221
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.6036659999068676
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6899773070419936
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.8088912462674839
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.6190453853872162
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 256
type: dim_256
metrics: type: cosine_accuracy@1
value: 0.7312588401697313
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8387553041018387
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8811881188118812
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9108910891089109
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7312588401697313
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5794436586515794
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5038189533239039
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3871287128712872
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.2253080829668273
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3769992784160216
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.46569418559764697
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5849776305212455
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6714462232907186
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7933903594441079
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.5983478967025827
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 128
type: dim_128
metrics: type: cosine_accuracy@1
value: 0.7072135785007072
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8104667609618105
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8472418670438473
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.8925035360678925
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7072135785007072
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5582272512965581
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.4746817538896747
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.36591230551626597
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.2156621291757699
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.35933791072495364
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.4340469332092486
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5496431686964021
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6371814381387044
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7686726835948902
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.5576428283947891
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 64
type: dim_64
metrics: type: cosine_accuracy@1
value: 0.6294200848656294
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.768033946251768
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8118811881188119
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.85997171145686
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.6294200848656294
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.504950495049505
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.43309759547383314
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3325318246110326
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.18996664340823183
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3217324319872244
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.38939140478827144
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.49869340790725203
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.5745644981495335
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7082149031229654
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.48618860343577813
name: Cosine Map@100
verified: no
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Created: 2025-06-09 12:34:35