Model: yasserrmd/endocrinology-gemma-300m-emb
Author: yasserrmd
Pipeline: sentence-similarity
Library: sentence-transformers
Tags: sentence-transformers, safetensors, gemma3_text, sentence-similarity, feature-extraction, dense, generated_from_trainer, dataset_size:20000, loss:MultipleNegativesRankingLoss, arxiv:1908.10084, arxiv:1705.00652, base_model:google/embeddinggemma-300m, base_model:finetune:google/embeddinggemma-300m, endpoints_compatible, region:us
Base models (finetune): id: google/embeddinggemma-300m
Card metadata: tags: sentence-transformers, sentence-similarity, feature-extraction, dense, generated_from_trainer, dataset_size:20000, loss:MultipleNegativesRankingLoss
base_model: google/embeddinggemma-300m
widget: source_sentence: What is the proposed alternate name for steroid responsive encephalopathy associated with Hashimoto's thyroiditis, and why is "Hashimoto's encephalopathy" still the universally accepted term?
sentences: Diabetes is associated with a series of vascular alterations, including intracranial atheroma, microangiopathy, cerebrovascular atherosclerosis, rheologic abnormalities, and endothelial changes. These alterations contribute to the marked damage in ischaemic cerebrovascular disease., The alternate name proposed for steroid responsive encephalopathy associated with Hashimoto's thyroiditis is "Hashimoto's encephalopathy." Despite the presence of normal thyroid function in the majority of cases, "Hashimoto's encephalopathy" remains the universally accepted term due to the coexistence of thyroid autoantibodies with several other forms of autoimmune encephalomenigitis, the normal MRI scan findings, and the initial dramatic response to steroids., The Centers for Disease Control's (CDC's) Advisory Committee on Immunization Practices recommends influenza and pneumococcal vaccines for all individuals with diabetes. This is due to the increased prevalence of drug-resistant influenza and pneumococcal disease, and related complications in the elderly. Vaccination is especially important for diabetes subjects as longer duration of diabetes and poor glycemic control increase the relative risk of pneumonia-related hospitalizations. The World Health Organization (WHO) states that people with diabetes are almost three times at higher risk of death due to pneumonia-related complications, highlighting the importance of vaccinations in this population., source_sentence: What are the potential effects of high aldosterone levels in patients with ileostomies?

sentences: Leptin levels increase with obesity and correlate significantly with body fat percentage. The association between leptin and cardiovascular disease may be partly influenced by genetic factors. It is suggested that leptin may reflect a state of hypothalamic leptin resistance in obesity and one of the co-occurrences of multiple vascular risk factors with obesity., The patient had high levels of adrenocorticotropic hormone (ACTH) and cortisol, indicating an endocrinological abnormality. To confirm the diagnosis of a central Cushing's disease (CD), a condition characterized by excessive production of ACTH by the pituitary gland, a dexamethasone suppression test was performed, which showed no distinct suppression. Further diagnostic procedures, including the repetition of the dexamethasone test and corticotropin-releasing hormone (CRH) stimulation, were performed. The patient displayed pathological midnight cortisol and ACTH levels, as well as pathological increases of cortisol and ACTH upon CRH stimulation. Petrosal sinus sampling was then performed, which confirmed the diagnosis of central CD by revealing a central-to-peripheral ACTH gradient., High aldosterone levels in patients with ileostomies can be associated with high ileostomy potassium concentrations. This may reflect physiological changes in the ileum similar to the effect of aldosterone on the kidney and colon. Increased transmucosal potential difference and increased K losses have been observed in aldosterone-treated patients. Aldosterone may favor the accumulation of higher levels of intraluminal potassium or directly affect active potassium transport in the mucosa. Some patients with an ileostomy may have normal plasma aldosterone levels despite intracellular sodium depletion, suggesting adaptation to a stable but depleted sodium state., source_sentence: How are medication adherence and glycated hemoglobin A1c (HbA1c) levels related in individuals with diabetes?

sentences: Thyroid hormones are involved in maintaining normal turnover and utilization of cholesterol at the cellular level. They play a significant role in the metabolism of cholesterols, which can impact the development of atherosclerosis. Dyslipidemia, characterized by atherogenic changes in blood lipids, is considered to represent a state of increased atherosclerosis. While overt hypothyroidism has been established to cause dyslipidemia, there is a need for further exploration of how subclinical hypothyroidism (SCH) with normal thyroid hormone levels can affect metabolic pathways and accelerate atherosclerotic lipid deposition within the vasculature., Unnecessary surgery for thyroid lumps can lead to complications such as hypothyroidism, hypoparathyroidism, and laryngeal nerve palsy., Medication adherence, both through electronic monitoring (EM) and self-report (SR), has been found to be significantly correlated with glycated hemoglobin A1c (HbA1c) levels in individuals with diabetes. Higher adherence rates, as measured by EM and SR, have been associated with lower HbA1c levels. This suggests that better medication adherence is associated with improved diabetes control, as reflected by lower HbA1c levels., source_sentence: What impact does glycaemic control have on the occurrence of cardiovascular events in post-transplant patients with diabetes?
sentences: Elevated plasma FFA concentrations in individuals with type 2 diabetes can have several negative effects on glucose metabolism. They can compete with glucose as an oxidative fuel in the muscle, inhibiting glucose uptake and utilization. FFAs can also impair insulin action in muscle, making it more difficult for insulin to stimulate glucose uptake. Additionally, elevated FFAs can increase hepatic gluconeogenesis (the production of glucose by the liver) and impair the ability of insulin to suppress hepatic glucose production. These effects contribute to the dysregulation of glucose levels in individuals with type 2 diabetes., Patients with diabetes mellitus (DM) and post-transplant diabetes mellitus (PTDM) have a higher frequency of cardiovascular events compared to those without DM. This increased risk persists despite the use of antihypertensive therapy and statins, suggesting that traditional risk factors alone may not accurately predict cardiovascular risk in this population. Glycemic management for these patients should align with the management of those with chronic kidney disease (CKD) to mitigate cardiovascular risk., The primary stimulus for the production of estrogen and other ovarian steroid hormones is the release of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), from the anterior pituitary. GNRH1, released from the hypothalamus, binds to the gonadotropin-releasing hormone receptor (GNRHR) in the anterior pituitary, leading to the activation of a phosphatidylinositol-calcium second messenger system. This ultimately triggers the release of FSH and LH, which play a crucial role in the production of estrogen and other ovarian steroid hormones., source_sentence: How does in utero exposure to excess anti-Müllerian hormone (AMH) affect the GnRH neuronal morphology and electrical activity in offspring?

sentences: The most common co-morbidities reported by patients with GHD are hypertension, arthritis, and diabetes mellitus. Additionally, 26% of patients had a history of fractures., Prophylactic thyroidectomy is recommended as early as the age of five years in confirmed RET mutation carriers in MEN2A or FMTC families with normal (stimulated) plasma calcitonin levels. However, some clinicians may prefer to wait until the pentagastrin test results are abnormal before performing thyroidectomy. This is because the test for calcitonin levels may give false negative results, and medullary thyroid carcinoma has been encountered in children with normal calcitonin levels who underwent thyroidectomy after DNA diagnosis., In utero exposure to excess AMH leads to protracted changes in GnRH neuronal morphology and electrical activity in offspring. PAMH female mice exhibit increased spine density on the soma and along the primary dendrite of GnRH neurons compared to controls during diestrus. This increased spine density is accompanied by a significant increase in the number of vesicular GABA transporter (vGaT) appositions onto GnRH cells. While there are no significant differences in the number of vesicular glutamate transporter 2 (vGluT2) appositions, it is important to note that GABA, although primarily recognized as an inhibitory neurotransmitter in the adult brain, is excitatory in adult GnRH neurons. This elevated hypothalamic excitatory apposition onto GnRH neurons in PAMH animals translates into increased neuronal activity.
pipeline_tag: sentence-similarity
library_name: sentence-transformers
Likes: 1 | All-time downloads: 32
Created: 2025-09-20 13:15:29