Model: potsu-potsu/bge-base-biomedical-matryoshka
Author: potsu-potsu
Pipeline: sentence-similarity
Library: sentence-transformers
Tags: sentence-transformers, safetensors, bert, sentence-similarity, feature-extraction, generated_from_trainer, dataset_size:4012, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss, en, arxiv:1908.10084, arxiv:2205.13147, arxiv:1705.00652, base_model:BAAI/bge-base-en-v1.5, base_model:finetune:BAAI/bge-base-en-v1.5, license:apache-2.0, model-index, text-embeddings-inference, endpoints_compatible, region:us
Base models (finetune): id: BAAI/bge-base-en-v1.5
Card metadata: language: en
license: apache-2.0
tags: sentence-transformers, sentence-similarity, feature-extraction, generated_from_trainer, dataset_size:4012, loss:MatryoshkaLoss, loss:MultipleNegativesRankingLoss
base_model: BAAI/bge-base-en-v1.5
widget: source_sentence: Do cephalopods use RNA editing less frequently than other species?
sentences: Extensive messenger RNA editing generates transcript and protein diversity in genes involved in neural excitability, as previously described, as well as in genes participating in a broad range of other cellular functions. , GV1001 is a 16-amino-acid vaccine peptide derived from the human telomerase reverse transcriptase sequence. It has been developed as a vaccine against various cancers., Using acetyl-specific K516 antibodies, we show that acetylation of endogenous S6K1 at this site is potently induced upon growth factor stimulation. We propose that K516 acetylation may serve to modulate important kinase-independent functions of S6K1 in response to growth factor signalling. Following mitogen stimulation, S6Ks interact with the p300 and p300/CBP-associated factor (PCAF) acetyltransferases. S6Ks can be acetylated by p300 and PCAF in vitro and S6K acetylation is detected in cells expressing p300, source_sentence: Can pets affect infant microbiomed?
sentences: Yes, exposure to household furry pets influences the gut microbiota of infants., Thiazovivin is a selective small molecule that directly targets Rho-associated kinase (ROCK) and increases expression of pluripotency factors.,  Here, we present evidence that the calcium/calmodulin-dependent protein kinase IV (CaMK4) is increased and required during Th17 cell differentiation. Inhibition of CaMK4 reduced Il17 transcription through decreased activation of the cAMP response element modulator a (CREM-a) and reduced activation of the AKT/mTOR pathway, which is known to enhance Th17 differentiation. CAMK4 knockdown and kinase-dead mutant inhibited crocin-mediated HO-1 expression, Nrf2 activation, and phosphorylation of Akt, indicating that HO-1 expression is mediated by CAMK4 and that Akt is a downstream mediator of CAMK4 in crocin signaling, source_sentence: In what proportion of children with heart failure has Enalapril been shown to be safe and effective?
sentences: 5-HT2A (5-hydroxytryptamine type 2a) receptor can be evaluated with the [18F]altanserin., In children with heart failure evidence of the effect of enalapril is empirical. Enalapril was clinically safe and effective in 50% to 80% of for children with cardiac failure secondary to congenital heart malformations before and after cardiac surgery,  impaired ventricular function , valvar regurgitation,  congestive cardiomyopathy,  , arterial hypertension, life-threatening arrhythmias coexisting with circulatory insufficiency.   
ACE inhibitors have shown a transient beneficial effect on heart failure due to anticancer drugs and possibly a beneficial effect in muscular dystrophy-associated cardiomyopathy, which deserves further studies., necroptosis
apoptosis  
pro-survival/inflammation NF-κB activation, source_sentence: How are SAHFS created?
sentences: In particular, up to 17% of neutrophil nuclei of healthy women exhibit a drumstick-shaped appendage that contains the inactive X chromosome., miR-1, miR-133, miR-208a, miR-206, miR-494, miR-146a, miR-222, miR-21, miR-221, miR-20a, miR-133a, miR-133b, miR-23, miR-107 and miR-181 are involved in exercise adaptation, Cellular senescence-associated heterochromatic foci (SAHFS) are a novel type of chromatin condensation involving alterations of linker histone H1 and linker DNA-binding proteins. SAHFS can be formed by a variety of cell types, but their mechanism of action remains unclear., source_sentence: What are the effects of the deletion of all three Pcdh clusters (tricluster deletion) in mice?
sentences: Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly. The vertebrate clustered protocadherin (Pcdh) cell surface proteins are encoded by three closely linked gene clusters (Pcdhα, Pcdhβ, and Pcdhγ). Although deletion of individual Pcdh clusters had subtle phenotypic consequences, the loss of all three clusters (tricluster deletion) led to a severe axonal arborization defect and loss of self-avoidance., The myocyte enhancer factor-2 (MEF2) proteins are MADS-box transcription factors that are essential for differentiation of all muscle lineages but their mechanisms of action remain largely undefined. MEF2C expression initiates cardiomyogenesis, resulting in the up-regulation of Brachyury T, bone morphogenetic protein-4, Nkx2-5, GATA-4, cardiac alpha-actin, and myosin heavy chain expression. Inactivation of the MEF2C gene causes cardiac developmental arrest and severe downregulation of a number of cardiac markers including atrial natriuretic factor (ANF). BMP-2, a regulator of cardiac development during embryogenesis, was shown to increase PI 3-kinase activity in cardiac precursor cells, resulting in increased expression of sarcomeric myosin heavy chain (MHC) and MEF-2A. Furthermore, expression of MEF-2A increased MHC expression in a PI 3-kinase-dependent manner. Other studies showed that Gli2 and MEF2C proteins form a complex, capable of synergizing on cardiomyogenesis-related promoters. Dominant interference of calcineurin/mAKAP binding blunts the increase in MEF2 transcriptional activity seen during myoblast differentiation, as well as the expression of endogenous MEF2-target genes. These findings show that MEF-2 can direct early stages of cell differentiation into a cardiomyogenic pathway., Investigators proposed that there have been three extended periods in the evolution of gene regulatory elements. Early vertebrate evolution was characterized by regulatory gains near transcription factors and developmental genes, but this trend was replaced by innovations near extracellular signaling genes, and then innovations near posttranslational protein modifiers.
pipeline_tag: sentence-similarity
library_name: sentence-transformers
metrics: cosine_accuracy@1, cosine_accuracy@3, cosine_accuracy@5, cosine_accuracy@10, cosine_precision@1, cosine_precision@3, cosine_precision@5, cosine_precision@10, cosine_recall@1, cosine_recall@3, cosine_recall@5, cosine_recall@10, cosine_ndcg@10, cosine_mrr@10, cosine_map@100
model-index: name: BGE Base Biomedical MRL
results: task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 768
type: dim_768
metrics: type: cosine_accuracy@1
value: 0.7524752475247525
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8628005657708628
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8995756718528995
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9222065063649222
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7524752475247525
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5973597359735974
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5162659123055162
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3977369165487977
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.2341252729014147
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3973567239272255
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.4854465714352775
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.6062286842357961
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6940262144509974
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.813453896410049
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.6257720133395309
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 512
type: dim_512
metrics: type: cosine_accuracy@1
value: 0.7538896746817539
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8585572842998586
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8953323903818954
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9207920792079208
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7538896746817539
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5964167845355963
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5142857142857143
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3977369165487976
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.2333750448173818
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.39469849211764985
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.4795534995350502
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.604605995019471
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6913260437859404
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.8125008419209268
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.6197252995126041
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 256
type: dim_256
metrics: type: cosine_accuracy@1
value: 0.7355021216407355
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8486562942008486
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8868458274398868
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.9137199434229137
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7355021216407355
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5818010372465817
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.5018387553041018
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.38896746817538896
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.22793567434972276
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.37898311614248786
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.4645337797167325
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5878379619993058
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6742555106189646
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7975213847915401
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.6002622001635138
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 128
type: dim_128
metrics: type: cosine_accuracy@1
value: 0.7057991513437057
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.8132956152758133
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.8500707213578501
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.8953323903818954
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.7057991513437057
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5535124941065536
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.47355021216407356
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.36605374823196607
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.2151445774205944
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.3572108621267904
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.4326304442151515
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.5469428314195238
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.6357672212173915
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7700377180575202
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.5565977979127998
name: Cosine Map@100
verified: no, task: type: information-retrieval
name: Information Retrieval
dataset: name: dim 64
type: dim_64
metrics: type: cosine_accuracy@1
value: 0.6265912305516266
name: Cosine Accuracy@1
verified: no, type: cosine_accuracy@3
value: 0.7666195190947667
name: Cosine Accuracy@3
verified: no, type: cosine_accuracy@5
value: 0.809052333804809
name: Cosine Accuracy@5
verified: no, type: cosine_accuracy@10
value: 0.85997171145686
name: Cosine Accuracy@10
verified: no, type: cosine_precision@1
value: 0.6265912305516266
name: Cosine Precision@1
verified: no, type: cosine_precision@3
value: 0.5002357378595002
name: Cosine Precision@3
verified: no, type: cosine_precision@5
value: 0.4291371994342292
name: Cosine Precision@5
verified: no, type: cosine_precision@10
value: 0.3312588401697313
name: Cosine Precision@10
verified: no, type: cosine_recall@1
value: 0.18851019998558088
name: Cosine Recall@1
verified: no, type: cosine_recall@3
value: 0.31756777149198423
name: Cosine Recall@3
verified: no, type: cosine_recall@5
value: 0.38736111738995704
name: Cosine Recall@5
verified: no, type: cosine_recall@10
value: 0.49729865330882483
name: Cosine Recall@10
verified: no, type: cosine_ndcg@10
value: 0.5709082950268725
name: Cosine Ndcg@10
verified: no, type: cosine_mrr@10
value: 0.7040951033878895
name: Cosine Mrr@10
verified: no, type: cosine_map@100
value: 0.4804032390680516
name: Cosine Map@100
verified: no
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Created: 2025-06-08 22:22:15