diff --git "a/it/test_it_ordered.csv" "b/it/test_it_ordered.csv" new file mode 100644--- /dev/null +++ "b/it/test_it_ordered.csv" @@ -0,0 +1,126 @@ +id,text,labels +190_94,"[['QUESTION', 'TYPE:', 'PEDIATRIA'], ['CLINICAL', 'CASE:'], ['Un', 'bambino', 'di', '18', 'mesi,', 'con', 'un', 'programma', 'di', 'vaccinazioni', 'completo', 'fino', 'a', 'quel', 'momento,', 'ha', 'consultato', 'il', 'Pronto', 'Soccorso', 'per', 'un', 'gonfiore', 'al', 'ginocchio', 'destro', 'dopo', 'aver', 'giocato', 'al', 'parco,', 'senza', 'traumi', 'evidenti.'], [""Nell'anamnesi"", 'diretta,', 'la', 'madre', 'riferisce', 'che', 'un', 'suo', 'zio', 'ha', 'avuto', 'problemi', 'simili.'], [""L'esame"", 'ecografico', 'era', 'compatibile', 'con', ""un'emartrosi"", 'e', ""l'analisi"", 'mostrava', 'solo', 'un', 'allungamento', ""dell'APTT"", 'di', ""52''"", '(normale', ""25-35'').""], ['Qual', 'è', ""l'ipotesi"", 'diagnostica', 'più', 'probabile?'], ['1-', 'Sindrome', 'di', 'Marfan.'], ['2-', 'Malattia', 'di', 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'Edinger-Westphal', 'al', 'muscolo', 'costrittore', 'della', 'pupilla', 'sinistra.'], ['5-', 'Il', 'muscolo', 'tarsale', 'esclusivamente.'], ['RISPOSTA', 'CORRETTA:', '1'], ['La', 'domanda', 'è', 'più', 'che', 'altro', 'di', 'neurologia.'], ['Si', 'tratta', 'della', 'sindrome', 'di', 'claude', 'bernard', 'horner', 'e', 'probabilmente', 'quella', 'corretta', 'è', 'la', '1'], ['Ma', 'per', 'sicurezza', 'è', 'meglio', 'farlo', 'controllare', 'da', 'un', 'neurologo.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 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['Angolo', 'di', 'Cobb', 'compreso', 'tra', '25º', 'e', '45º.'], ['Scheletro', 'immaturo', '(Risser', '0).']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'B-Premise', 'I-Premise']]" +489_105,"[['QUESTION', 'TYPE:', 'EMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Paziente', 'di', '67', 'anni', 'che', 'negli', 'ultimi', '6', 'mesi,', 'in', 'due', 'analisi', 'di', 'routine,', 'ha', 'presentato', 'una', 'linfocitosi', 'progressiva.'], ['In', ""quest'ultimo,"", 'emoglobina', '15,4', 'g/dl;', 'leucociti', '18,5', 'x103/μL', 'con', ""l'82%"", 'di', 'linfociti', 'maturi', 'che', 'esprimono', 'antigeni', 'CD5/CD19/CD23', 'mediante', 'citometria', 'a', 'flusso', 'e', 'piastrine', '240', 'x103/μL.'], ['Quale', 'atteggiamento', 'pensate', 'sia', 'giusto?'], ['1-', 'Studio', 'delle', 'mutazioni', 'di', 'TP53', 'per', 'stabilire', 'la', 'prognosi.'], ['2-', 'Aspirato', 'osseo/biopsia', 'per', 'confermare', 'la', 'diagnosi.'], ['3-', 'PET/CT', 'per', 'stabilire', ""l'approccio"", 'terapeutico.'], ['4-', 'Nuovo', 'controllo', 'clinico', 'e', 'analitico', 'in', '6', 'mesi.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '4'], ['Il', 'paziente', 'ha', 'già', 'ricevuto', 'una', 'diagnosi', 'di', 'leucemia', 'linfocitica', 'cronica', 'B', '(B-CLLL),', 'presenta', 'una', 'linfocitosi', 'presente', 'da', 'più', 'di', '3', 'mesi', 'e', 'un', 'fenotipo', 'compatibile', 'con', 'essa', 'mediante', 'citometria', 'a', 'flusso.'], ['Pertanto,', 'dobbiamo', 'prima', 'conoscere', 'i', 'fattori', 'di', 'rischio', 'che', 'indicheranno', 'la', 'priorità', 'con', 'cui', 'dovrà', 'essere', 'iniziato', 'il', 'trattamento,', ""l'intensità"", 'di', 'questi', 'fattori', 'e', 'la', 'prognosi,', 'da', 'cui', 'dipende', 'la', 'presenza', 'di', 'mutazioni', 'TP53', 'o', 'delezioni', '17p.'], [""L'aspirato"", 'midollare', 'o', 'la', 'biopsia', 'sono', 'indicati', 'solo', 'se', 'ci', 'sono', 'altre', 'citopenie', 'di', 'accompagnamento', 'che', 'non', 'sono', 'giustificate', 'dalla', 'B-CLL', 'stessa,', 'la', 'PET-CT', 'è', 'indicata', 'solo', 'se', 'si', 'sospetta', 'la', 'sindrome', 'di', 'Ritcher', 'e', 'non', 'ci', 'sono', 'dati', 'sufficienti', 'per', 'sospettarla,', 'non', 'ci', 'sono', 'sintomi', 'B,', 'né', 'si', 'parla', 'di', 'LDH', 'elevato.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]" +534_119,"[['QUESTION', 'TYPE:', 'REUMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'paziente', 'di', '45', 'anni', 'con', 'anamnesi', 'di', 'reflusso', 'gastro-esofageo', 'presenta', 'da', 'un', 'anno', 'episodi', 'di', 'pallore', 'in', 'alcune', 'dita', ""all'esposizione"", 'al', 'freddo.'], ['Recentemente', 'gli', 'era', 'stato', 'prescritto', 'il', 'prednisone', 'alla', 'dose', 'di', '20', 'mg/die', 'per', 'i', 'dolori', 'articolari', 'e', ""l'indurimento"", 'della', 'pelle', 'delle', 'mani', 'e', 'delle', 'braccia.'], ['Si', 'sentiva', 'male', 'da', '48', 'ore', 'e', 'aveva', 'un', 'forte', 'mal', 'di', 'testa,', 'per', 'il', 'quale', 'si', 'era', 'recata', 'al', 'pronto', 'soccorso.'], [""L'esame"", 'ha', 'rivelato', 'solo', 'una', 'tachicardia', 'ritmica', 'a', '100', 'bpm,', 'senza', 'alcuna', 'focalità', 'neurologica.'], ['La', 'pressione', 'arteriosa', 'è', 'di', '200/110', 'mmHg.'], [""L'esame"", 'del', 'sangue', 'ha', 'mostrato', 'solo', 'un', 'livello', 'di', 'creatinina', 'di', '2,5', 'mg/dl.'], ['Indicare', 'quale', 'dei', 'seguenti', 'autoanticorpi', 'si', 'riferisce', 'meglio', 'al', 'processo', 'descritto:'], ['1-', 'Anticorpi', 'anti-RNA', 'polimerasi', 'III.'], ['2-', 'Anticorpi', 'anti-centromero.'], ['3-', 'Anticorpi', 'anti-proteinasi', '3'], ['4-', 'Anticorpi', 'anti-PM-Scl.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '1'], ['Si', 'tratta', 'di', 'un', 'chiaro', 'caso', 'clinico', 'di', 'sclerosi', 'sistemica', '(Raynaud,', 'coinvolgimento', 'esofageo,', 'indurimento', 'cutaneo)', 'che', 'si', 'presenta', 'con', 'una', 'crisi', 'renale.'], ['Oltre', 'agli', 'anticorpi', 'anti-proteinasi', '3,', 'che', 'non', 'sono', 'associati', 'alla', 'sclerodermia', '(risposta', 'errata', '3),', 'i', 'più', 'probabili', 'sono', 'gli', 'anticorpi', 'anti-RNA', 'polimerasi', 'III,', 'che', 'compaiono', 'nei', 'pazienti', 'più', 'giovani', 'con', 'crisi', 'renali.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +273_71,"[['QUESTION', 'TYPE:', 'APPARATO', 'DIGERENTE'], ['CLINICAL', 'CASE:'], ['Un', 'giovane', 'di', '18', 'anni', 'con', ""un'anamnesi"", 'di', 'asma,', 'allergia', 'ai', 'pollini,', 'agli', 'acari', 'e', 'al', 'pelo', 'di', 'gatto,', 'si', 'è', 'presentato', 'al', 'pronto', 'soccorso', 'lamentando', 'una', 'sensazione', 'di', 'impattamento', 'alimentare', 'retrosternale', 'con', 'pratica', 'incapacità', 'di', 'deglutire', 'la', 'propria', 'saliva.'], ['Riferisce', 'di', 'episodi', 'simili', 'in', 'altre', 'occasioni', 'che', 'si', 'sono', 'attenuati', 'spontaneamente', 'nel', 'giro', 'di', 'pochi', 'minuti.'], ['Quale', 'delle', 'seguenti', 'è', 'la', 'diagnosi', 'più', 'probabile?'], ['1-', 'Esofago', 'di', 'Barrett.'], ['2-', 'Anello', 'esofageo', 'distale', '(Schatzki).'], ['3-', 'Esofagite', 'infettiva.'], ['4-', 'Esofagite', 'eosinofila.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '4'], ['Si', 'tratta', 'di', 'disfagia', 'intermittente.'], [""L'esofago"", 'di', 'Barrett', 'non', 'implica', 'necessariamente', 'una', 'stenosi', 'peptica,', 'ma', 'se', 'lo', 'è,', 'è', 'progressivo.'], [""L'esofagite"", 'infettiva', 'è', 'più', 'comune', 'nei', 'pazienti', 'immunocompromessi.'], ['Rimangono', ""l'anello"", 'esofageo', 'distale', 'e', ""l'esofagite"", 'eosinofila;', 'entrambi', 'sono', 'possibili,', 'ma', ""l'insistenza"", 'sul', 'carico', 'atopico', 'del', 'paziente', 'indica', 'la', 'probabilità', 'della', 'seconda', 'ipotesi.']]","[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +56_76,"[['QUESTION', 'TYPE:', 'ENDOCRINOLOGIA'], ['CLINICAL', 'CASE:'], ['Ragazza', 'di', '14', 'anni', 'che', 'si', 'consulta', 'per', 'una', 'diminuzione', 'della', 'crescita', 'da', '2-3', 'anni', 'prima', 'normale', '(fornisce', 'i', 'dati)', 'e', 'che', 'le', 'altre', 'ragazze', 'della', 'sua', 'età', 'hanno', 'un', 'maggiore', 'sviluppo', 'fisico', 'e', 'sessuale.'], ['Ultimamente', 'ha', 'avuto', 'mal', 'di', 'testa', 'e', 'problemi', 'visivi', 'che', 'ha', 'notato', 'in', 'classe', 'e', 'durante', 'lo', 'studio.'], ['Non', 'ha', 'avuto', 'menarca', 'o', 'polidipsia', 'o', 'poliuria.'], ['Genitori', 'con', 'dimensioni', 'normali.'], ['Esame:', 'bassa', 'statura', 'a', '-2,1', 'deviazioni', 'standard,', 'proporzioni', 'corporee', 'normali,', 'pochi', 'peli', 'pubici', 'e', 'sviluppo', 'del', 'seno.'], ['La', 'campimetria', 'mostra', ""un'emianopsia"", 'parziale', 'temporale', 'sinistra.'], ['Età', 'ossea:', 'ritardata', 'di', '2', 'anni.'], ['Emocromo', 'normale.'], ['Basse', 'gonadotropine', '(FSH', 'e', 'LH)', 'ed', 'estradiolo.'], ['Quale', 'pensate', 'sia', 'la', 'risposta', 'più', 'appropriata?'], ['1-', 'La', 'diminuzione', 'della', 'crescita', 'e', 'dello', 'sviluppo', 'sessuale,', 'il', 'ritardo', ""dell'età"", 'ossea,', 'la', 'cefalea', 'e', 'i', 'disturbi', 'visivi', 'suggeriscono', 'un', 'deficit', 'ormonale', 'e', 'il', 'coinvolgimento', 'del', 'chiasma', 'ottico.'], ['2-', 'Essendo', 'una', 'ragazza', 'in', 'età', 'puberale,', 'è', 'molto', 'probabile', 'che', 'la', 'crescita', 'stentata', 'e', 'il', 'ritardo', 'sessuale', 'siano', 'dovuti', 'alla', 'sindrome', 'di', 'Turner.'], ['3-', 'Non', 'deve', 'avere', 'un', 'tumore', 'ipotalamico', 'per', ""l'assenza"", 'di', 'poliuria', 'e', 'polidipsia.', 'Probabilmente', 'ha', 'un', 'ritardo', 'costituzionale', 'e', 'il', 'suo', 'problema', 'visivo', 'è', 'un', 'problema', 'di', 'rifrazione.'], ['4-', 'Una', 'carenza', 'di', 'ormone', 'della', 'crescita', 'può', 'spiegare', 'il', 'ritardo', 'nello', 'sviluppo', 'e', 'il', 'basso', 'livello', 'di', 'estradiolo.', 'Valutare', 'se', 'ha', 'bisogno', 'di', 'occhiali,', 'a', 'causa', 'di', 'cefalee', 'e', 'disturbi', 'visivi.'], ['5-', 'Potrebbe', 'avere', 'un', 'craniofaringioma,', 'ma', 'sarebbe', 'strano', 'se', 'non', 'avesse', 'manifestato', 'sintomi', 'in', 'precedenza.', 'Inoltre,', 'non', 'giustificherebbe', 'le', 'gonadotropine', 'basse', 'e', ""l'estradiolo"", 'basso.'], ['RISPOSTA', 'CORRETTA:', '1'], ['La', 'risposta', '2', 'è', 'falsa', '(sindrome', 'di', 'Turner:', 'estradiolo', 'basso', 'e', 'gonadotropine', 'elevate),', 'i', 'tumori', 'cerebrali', 'che', 'colpiscono', ""l'ipotalamo-ipofisi"", 'non', 'danno', 'gonadotropine', 'basse', '(5', 'falso)', 'e', 'sembra', 'ovvio', 'che', 'i', 'difetti', 'di', 'rifrazione', 'non', 'diano', 'emianopsia', '(3', 'e', '4', 'falso).']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 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'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +409_191,"[['QUESTION', 'TYPE:', 'CURA', 'PRIMARIA'], ['CLINICAL', 'CASE:'], ['Si', 'reca', 'a', 'casa', 'di', 'un', 'paziente', 'oncologico', 'il', 'cui', 'dolore', 'non', 'è', 'stato', 'ben', 'controllato', 'negli', 'ultimi', 'tempi.'], [""All'esame"", 'fisico', 'non', 'sembra', 'esserci', 'alcuna', 'evidenza', 'di', 'progressione', 'del', 'tumore', 'e', 'non', 'sono', 'stati', 'rilevati', 'reperti', 'di', 'interesse', 'precedentemente', 'noti.'], [""Nell'anamnesi,"", ""l'assistente"", 'principale', 'dichiara', 'che', 'il', 'paziente', 'ha', 'dolore', '8', 'ore', 'dopo', 'aver', 'ricevuto', 'la', 'dose', 'basale', 'di', 'morfina', 'prescritta', 'ogni', '12', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O']]" +579_108,"[['QUESTION', 'TYPE:', 'NEUROLOGIA'], ['CLINICAL', 'CASE:'], ['Uomo', 'di', '49', 'anni', 'ricoverato', 'in', 'terapia', 'intensiva', 'per', 'lesioni', 'cerebrali', 'traumatiche', 'in', 'seguito', 'a', 'un', 'incidente', 'sul', 'lavoro.'], [""All'esame"", 'fisico,', 'non', 'apre', 'gli', 'occhi,', 'non', 'emette', 'suoni', 'prima', ""dell'intubazione"", 'e', 'mostra', 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'aumento', 'del', 'flusso', 'sanguigno', 'cerebrale.'], ['Secondo', ""l'esame"", 'descritto,', 'il', 'punteggio', 'di', 'Glasgow', 'è', '4', '(O1V1M2).'], ['La', 'pressione', 'di', 'perfusione', 'cerebrale', 'è', 'la', 'pressione', 'arteriosa', 'media', 'meno', 'la', 'pressione', 'intracranica.'], [""L'edema"", 'cerebrale,', 'in', 'cui', ""l'edema"", 'cellulare', 'è', 'causato', ""dall'introduzione"", 'di', 'liquido', 'extracellulare', 'nel', 'compartimento', 'intracellulare,', 'è', 'citotossico.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +212_88,"[['QUESTION', 'TYPE:', 'CHIRURGIA', 'GENERALE'], ['CLINICAL', 'CASE:'], ['Un', 'uomo', 'di', '45', 'anni', 'è', 'stato', 'sottoposto', 'a', 'vagotomia', 'troncale', 'e', 'antrectomia', 'con', 'ricostruzione', 'Billroth', 'II', 'per', 'malattia', 'cronica', 'da', 'ulcera', 'peptica', 'con', 'stenosi', 'piloro-duodenale.'], ['Sei', 'settimane', 'dopo', ""l'intervento,"", 'ha', 'riferito', 'che', 'poco', 'dopo', ""l'ingestione"", '(meno', 'di', ""mezz'ora)"", 'ha', 'accusato', 'nausea,', 'astenia', 'e', 'sudorazione,', 'vertigini', 'e', 'crampi', 'addominali', 'generalmente', 'accompagnati', 'da', 'scariche', 'diarroiche.'], ['Quale', 'dei', 'seguenti', 'è', ""l'atteggiamento"", 'più', 'appropriato', 'per', 'la', 'gestione', 'iniziale?'], ['1-', 'Trattamento', 'con', 'un', 'inibitore', 'della', 'somatostatina', '(octreotide).'], ['2-', 'Seguire', 'misure', 'dietetiche', 'specifiche.'], ['3-', 'Effettuare', 'un', 'trattamento', 'di', 'prova', 'con', 'una', 'benzodiazepina.'], ['4-', 'Ricerca', 'di', 'un', 'probabile', 'tumore', 'neuroendocrino', '(ad', 'es.', 'carcinoide).'], ['5-', 'Indicare', 'il', 'trattamento', 'chirurgico', 'per', 'eseguire', 'una', 'gastrogiunostomia', 'Roux-en-Y', 'antiperistaltica.'], ['RISPOSTA', 'CORRETTA:', '2'], ['Le', 'risposte', '1,', '2', 'e', '5', 'sono', 'trattamenti', 'appropriati', 'per', 'la', 'sindrome', 'da', 'dumping', 'o', 'per', 'la', 'postgastrectomia,', 'ma', 'la', 'domanda', 'è', 'focalizzata', 'sulla', 'gestione', 'iniziale,', 'quindi', 'la', 'risposta', 'più', 'appropriata', 'sembra', 'essere', 'la', '2']]","[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +507_89,"[['QUESTION', 'TYPE:', 'PSICHIATRIA'], ['CLINICAL', 'CASE:'], ['Un', 'uomo', 'di', '46', 'anni', 'con', 'disturbo', 'bipolare', 'viene', 'portato', 'al', 'pronto', 'soccorso', 'dopo', ""un'overdose"", 'di', 'carbonato', 'di', 'litio.'], [""L'esame"", 'rivela', 'tremore', 'intenso,', 'atassia,', 'disartria,', 'mioclono', 'e', 'fascicolazioni.'], ['La', 'litemia', 'è', 'di', '4,1', 'mEq/L', '(tossicità', '>', '1,6', 'mEq/L).'], ['Quale', 'delle', 'seguenti', 'opzioni', 'terapeutiche', 'sarebbe', 'più', 'appropriata?'], ['1-', 'Aminofillina', 'associata', 'a', 'un', 'catartico.'], ['2-', 'Carbone', 'attivo.'], ['3-', 'Emodialisi.'], ['4-', 'Diuresi', 'forzata.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Attenzione', 'al', 'litio.'], ['Sono', 'state', 'osservate', 'intossicazioni', 'con', 'una', 'normale', 'litiemia.'], ['Non', 'è', 'raro,', 'soprattutto', 'in', 'termini', 'di', 'interazioni.'], ['Un', 'farmaco', 'molto', 'efficace', 'se', 'si', 'fa', 'prevenzione.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +552_89,"[['QUESTION', 'TYPE:', 'DERMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'bambina', 'di', '4', 'anni', 'si', 'presenta', 'con', 'febbre', 'alta', 'da', '6', 'giorni.'], [""L'esame"", 'clinico', 'ha', 'rivelato', ""un'eruzione"", 'maculopapulare', 'eritematosa', 'sul', 'tronco', 'e', ""sull'area"", 'genitale,', 'con', 'tendenza', 'alla', 'confluenza,', 'senza', 'diventare', 'scarlattiniforme;', 'iniezione', 'congiuntivale', 'senza', 'scarico', 'e', 'labbra', 'rosse', 'con', 'lingua', 'a', 'lampone.'], ['Erano', 'inoltre', 'presenti', 'eritema', 'con', 'edema', 'alle', 'mani', 'e', 'ai', 'piedi', 'e', 'una', 'linfoadenopatia', 'cervicale', 'unilaterale', 'di', '2', 'cm', 'di', 'diametro.'], ['La', 'diagnosi', 'clinica', 'più', 'probabile', 'è', 'quella', 'di', 'sospetto:'], ['1-', 'Malattia', 'di', 'Kawasaki.'], ['2-', 'Morbillo.'], ['3-', 'Rosolia.'], ['4-', 'Scarlattina.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '1'], ['Indubbiamente,', 'non', 'soddisfano', 'i', 'criteri', 'diagnostici', 'della', 'malattia', 'di', 'Kawasaki', '(febbre', 'di', 'diversi', 'giorni,', 'eruzione', 'cutanea,', 'iniezione', 'congiuntivale,', 'labbra', 'rosse,', 'lingua', 'a', 'lampone,', 'edema', 'delle', 'parti', 'acrali', 'e', 'adenopatia).']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]" +598_181,"[['QUESTION', 'TYPE:', 'REUMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Un', 'uomo', 'di', '67', 'anni', 'si', 'è', 'presentato', 'con', '3', 'mesi', 'di', 'astenia', 'e', 'febbre,', 'a', 'cui', 'si', 'è', 'aggiunta', ""nell'ultimo"", 'mese', ""l'ostruzione"", 'nasale', 'con', 'emissione', 'di', 'muco', 'con', 'alcuni', 'coaguli.'], ['Negli', 'ultimi', 'giorni', 'ha', 'notato', 'dolore', ""all'occhio"", 'destro', 'e', 'asimmetria', 'rispetto', ""all'occhio"", 'controlaterale.'], [""L'esame"", 'fisico', 'ha', 'rivelato', 'una', 'proptosi', 'del', 'bulbo', 'oculare', 'destro', 'e', ""l'ispezione"", 'delle', 'narici', 'ha', 'evidenziato', 'una', 'mucosa', 'eritematosa', 'con', 'croste', 'sierologiche.'], ['Il', 'resto', ""dell'esame"", 'è', 'normale.'], ['Gli', 'esami', 'del', 'sangue', '(emogramma,', 'funzionalità', 'renale', 'ed', 'epatica)', 'sono', 'normali,', 'ad', 'eccezione', 'di', 'una', 'VES', 'di', '65', 'mm/h;', 'le', 'analisi', 'delle', 'urine', 'mostrano', 'microematuria', 'e', 'proteinuria', 'di', '520', 'mg/24h.'], ['Qual', 'è', 'la', 'diagnosi', 'iniziale', 'più', 'probabile?'], ['1-', 'Granulomatosi', 'eosinofila', 'con', 'poliangioite.'], ['2-', 'Poliangioite', 'microscopica.'], ['3-', 'Granulomatosi', 'con', 'poliangioite.'], ['4-', 'Poliarterite', 'nudosa.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Il', 'paziente', 'presenta', 'una', 'granulomatosi', 'con', 'poliangioite,', 'precedentemente', 'nota', 'come', 'granulomatosi', 'di', 'Wegener.'], ['Nel', 'caso', 'clinico', 'si', 'parla', 'di', ""un'affezione"", 'otorinolaringoiatrica', 'presente', 'nel', '92%', 'dei', 'pazienti.'], ['A', 'livello', 'polmonare,', 'ha', 'detto', 'di', 'aver', 'presentato', 'muco', 'con', 'alcuni', 'coaguli;', 'questo', 'tipo', 'di', 'affezione', 'è', 'presente', ""nell'85%"", 'dei', 'pazienti.'], ['Inoltre,', 'alla', 'fine', 'del', 'caso,', ""l'analisi"", 'delle', 'urine', 'ha', 'mostrato', 'una', 'glomerulonefrite,', 'presente', 'nel', '77%', 'dei', 'pazienti.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 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'MICROBIOLOGIA'], ['CLINICAL', 'CASE:'], ['Incinta,', '27', 'anni,', '30', 'settimane', 'di', 'gestazione.'], ['Ieri', 'si', 'è', 'recata', 'al', 'pronto', 'soccorso', 'dopo', 'aver', 'avvertito', 'dolore', 'nella', 'regione', 'lombare', 'sinistra', 'e', 'disuria.'], ['Nessuna', 'sensazione', 'di', 'febbre.'], ['Si', 'riferisce', 'a', 'ripetute', 'infezioni', 'del', 'tratto', 'urinario', '(UTI).'], ['Le', 'analisi', 'delle', 'urine', 'mostrano', 'Hb', '3+,', 'leucociti', '3+,', 'nitriti', '2+,', 'Sedimento:', '15-20', 'leucociti', 'per', 'campo', 'e', '5-10', 'globuli', 'rossi', 'per', 'campo.'], ['Quale', 'dei', 'seguenti', 'microrganismi', 'è', 'la', 'causa', 'più', 'frequente', 'nelle', 'donne', 'in', 'gravidanza?'], ['1-', 'Escherichia', 'coli.'], ['2-', 'Enterococcus', 'faecalis.'], ['3-', 'Streptococcus', 'agalactiae.'], ['4-', 'Proteus', 'mirabilis.'], ['5-', 'Satphylococcus', 'saprophyticus.'], ['RISPOSTA', 'CORRETTA:', '1'], ['La', 'risposta', 'corretta', 'è', 'la', 'prima.'], ['La', 'causa', 'più', 'comune', 'di', 'infezioni', 'del', 'tratto', 'urinario', 'è', ""l'Escherichia"", 'coli', 'e', 'anche', 'nelle', 'donne', 'in', 'gravidanza.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +522_165,"[['QUESTION', 'TYPE:', 'ENDOCRINOLOGIA'], ['CLINICAL', 'CASE:'], ['Donna', 'di', '66', 'anni', 'a', 'cui', 'è', 'stato', 'diagnosticato', 'il', 'diabete', 'mellito', 'di', 'tipo', '2', 'tre', 'mesi', 'fa.'], ['Ha', 'un', 'IMC', 'di', '31', 'kg/m2', 'e', 'un', 'controllo', 'glicemico', 'insufficiente', 'nonostante', 'un', 'programma', 'di', 'misure', 'non', 'farmacologiche', '(dieta', 'sana,', 'esercizio', 'fisico).'], ['Quale', 'dei', 'seguenti', 'farmaci', 'ipoglicemizzanti', 'è', 'associato', ""all'aumento"", 'di', 'peso', 'e', 'dovrebbe', 'essere', 'evitato', 'in', 'questo', 'paziente?'], ['1-', 'Metformina', '(biguanide).'], ['2-', 'Pioglitazona', '(tiazolidindiona).'], ['3-', 'Canagliflozin', '(inibitore', 'del', 'cotrasportatore', '2', 'del', 'sodio-glucosio', '-', 'iSGLT2).'], ['4-', 'Liraglutide', '(agonista', 'del', 'recettore', 'GLP-1).'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '2'], ['Una', 'domanda', 'un', ""po'"", 'più', 'complicata', 'della', 'precedente.'], ['In', 'termini', 'di', 'peso,', 'la', 'metformina,', 'in', 'misura', 'minore,', 'gli', 'inibitori', 'del', 'SGLT-2', 'e,', 'soprattutto,', 'gli', 'agonisti', 'del', 'GLP-1', 'sono', 'stati', 'associati', 'a', 'una', 'significativa', 'riduzione', 'del', 'peso', 'nei', 'pazienti', 'con', 'DM-2', '(risposte', '1,', '3', 'e', '4', 'errate).'], ['Al', 'contrario,', 'il', 'pioglitazone,', 'come', 'indicato', 'nella', 'sua', 'etichetta,', 'può', 'causare', 'un', 'aumento', 'di', 'peso', 'dose-dipendente,', 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'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +209_185,"[['QUESTION', 'TYPE:', 'GINECOLOGIA', 'E', 'OSTETRICIA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '32', 'anni', 'chiede', 'una', 'consulenza', 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'partire', 'dalla', '19-20', 'settimana', 'di', 'gestazione.'], ['3-', 'Consiglierei', 'un', 'cerchiaggio', 'cervicale', 'a', '14', 'settimane', 'di', 'gestazione.'], ['4-', 'Le', 'consiglierei', 'di', 'non', 'tentare', 'altre', 'gravidanze', 'a', 'causa', ""dell'elevato"", 'rischio', 'di', 'recidiva.'], ['5-', 'Consiglierei', 'di', 'ricorrere', 'a', 'tecniche', 'di', 'riproduzione', 'assistita.'], ['RISPOSTA', 'CORRETTA:', '3'], ['Questo', 'è', 'un', 'tipico', 'caso', 'di', 'incompetenza', 'cervicale', '(e', 'questa', 'paziente', 'ha', 'la', 'conizzazione', 'come', 'fattore', 'di', 'rischio).'], ['Questa', 'patologia', 'consiste', 'nella', 'dilatazione', 'del', 'collo', ""dell'utero"", 'in', 'assenza', 'di', 'contrazioni,', 'che', 'richiede', 'il', 'cerchiaggio', 'per', 'evitare', ""l'aborto"", 'o', 'il', 'travaglio', 'immaturo.'], ['Idealmente,', 'il', 'cerchiaggio', 'viene', 'eseguito', 'elettivamente,', 'su', 'base', 'programmata,', 'e', 'non', 'quando', 'la', 'paziente', 'arriva', 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'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +282_55,, +464_155,"[['QUESTION', 'TYPE:', 'CURE', 'CRITICHE', 'ED', 'EMERGENZE'], ['CLINICAL', 'CASE:'], ['Un', 'uomo', 'di', '58', 'anni,', 'tre', 'settimane', 'dopo', 'una', 'grave', 'distorsione', 'alla', 'caviglia,', 'ha', 'presentato', 'una', 'dispnea', 'a', 'riposo', 'rapidamente', 'progressiva,', 'vertigini', 'e', 'sincope.'], [""All'arrivo"", 'in', 'ospedale', 'presenta', 'ipotensione', '(pressione', 'sistolica', '80', 'mmHg,', 'diastolica', '40', 'mmHg)', 'e', 'scarsa', 'perfusione.'], ['Viene', 'intubato', 'e', 'collegato', 'alla', 'ventilazione', 'meccanica', 'e', 'viene', 'iniziata', 'la', 'somministrazione', 'di', 'noradrenalina.'], [""L'ecocardiogramma"", 'mostra', 'segni', 'di', 'ipertensione', 'polmonare.'], [""L'angio-TC"", 'mostra', 'difetti', 'multipli', 'di', 'replezione', 'che', 'occupano', 'entrambe', 'le', 'arterie', 'polmonari', 'principali.'], ['Quale', 'dei', 'seguenti', 'trattamenti', 'sarebbe', 'associato', 'al', 'più', 'rapido', 'miglioramento', 'emodinamico', 'in', 'questo', 'caso?'], ['1-', 'Infusione', 'endovenosa', 'di', 'eparina', 'sodica.'], ['2-', 'Tromboendartectomia.'], ['3-', 'Fibrinolisi', 'sistemica', 'con', 'rt-PA', '(alteplase)', '100', 'mg', 'per', 'via', 'endovenosa.'], ['4-', 'Filtro', 'per', 'la', 'vena', 'cava', 'inferiore.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Il', 'paziente', 'ha', 'presentato', 'una', 'tromboembolia', 'polmonare', 'che,', 'oltre', 'a', 'essere', 'bilaterale,', 'ha', 'causato', 'una', 'grave', 'compromissione', 'emodinamica,', 'shock', 'e', 'ha', 'richiesto', 'la', 'ventilazione', 'meccanica.'], ['Non', 'ci', 'risulta', 'che', 'ci', 'siano', 'controindicazioni', 'alla', 'fibrinolisi,', 'quindi', 'questa', 'sarebbe', ""l'opzione"", 'più', 'appropriata', 'per', 'la', 'sua', 'rapidità', 'di', 'somministrazione', 'e', 'di', 'azione.'], [""L'eparina"", 'sodica', 'è', 'riservata', 'ai', 'casi', 'in', 'cui', 'il', 'paziente', 'è', 'stabile.'], ['La', 'tromboendarterectomia', 'potrebbe', 'essere', 'eseguita', 'in', 'emergenza', 'in', 'centri', 'selezionati', '(non', 'disponibili', 'in', 'tutti)', 'in', 'pazienti', 'in', 'cui', 'la', 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['2-', 'PESCE.'], ['3-', 'Microarray', 'di', 'DNA', 'e/o', 'RNA.'], ['4-', 'Cariotipo.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '4'], ['Questa', 'domanda', 'potrebbe', 'essere', 'un', ""po'"", 'più', 'difficile,', 'poiché', 'il', 'caso', 'clinico', 'che', 'ci', 'è', 'stato', 'presentato', 'è', 'molto', 'vago.'], ['Una', 'ragazza', 'adolescente', 'con', 'ritardo', 'puberale', 'e', 'bassa', 'statura;', 'niente', 'di', 'più.'], ['Con', 'queste', 'informazioni,', 'potrebbe', 'avere', 'diverse', 'patologie', 'su', 'base', 'genetica,', 'ma', 'questa', 'è', 'la', 'MIR', 'e', 'ci', 'viene', 'anche', 'detto', 'che', 'la', 'paziente', 'non', 'ha', 'una', 'disabilità', 'intellettiva.'], ['Nel', 'MIR,', 'una', 'ragazza', 'adolescente', 'con', 'ritardo', 'puberale', 'e', 'bassa', 'statura', 'deve', 'essere', 'una', 'Turner', 'fino', 'a', 'prova', 'contraria', '(nel', '2017', ""c'erano"", 'due', 'domande).'], ['Pertanto,', 'se', 'questo', 'è', 'il', 'nostro', 'primo', 'sospetto', 'diagnostico,', 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'tratta', 'di', 'una', 'nefropatia', 'da', 'IgA', 'con', 'insufficienza', 'renale', 'acuta.'], ['2-', 'Sarebbe', 'indicata', 'la', 'plasmaferesi.'], ['3-', 'Si', 'tratta', 'di', 'glomerulonefrite', 'membranosa.'], ['4-', 'Il', 'micofenolato', 'mofetile', 'è', 'il', 'trattamento', 'iniziale', 'di', 'scelta.'], ['5-', 'Il', 'coinvolgimento', 'glomerulare', 'è', 'causato', 'dalla', 'presenza', 'di', 'immunocomplessi', 'circolanti.'], ['RISPOSTA', 'CORRETTA:', '2'], ['Il', 'sospetto', 'diagnostico', 'basato', 'sui', 'dati', 'forniti', '(in', 'particolare', 'gli', 'anticorpi', 'anti-GBM', 'e', 'la', 'presenza', 'di', 'sindrome', 'renopolmonare)', 'è', 'quello', 'della', 'sindrome', 'di', 'Goodpasture.'], ['Tutti', 'gli', 'altri', 'dati', '(seminole', 'alla', 'biopsia,', 'deposito', 'lineare', 'di', 'IgG)', 'supportano', 'la', 'diagnosi.'], ['Sapendo', 'questo,', 'le', 'opzioni', 'sono', 'facilmente', 'scartate:', ""l'opzione"", '1', 'parla', 'di', 'una', 'nefropatia', 'da', 'IgA', '(non', 'è', 'così,', 'perché', 'i', 'depositi', 'sono', 'di', 'IgG);', 'anche', ""l'opzione"", '3', 'è', 'scartata,', 'perché', 'non', 'si', 'tratta', 'di', 'una', 'GMN', 'primaria,', 'come', 'la', 'GMN', 'membranosa,', 'ma', 'di', 'una', 'glomerulopatia', 'secondaria;', 'anche', ""l'opzione"", '4', 'è', 'falsa:', 'il', 'trattamento', 'iniziale', 'è', 'con', 'corticosteroidi', 'e', 'ciclofosfamide', 'associati', 'a', 'plasmaferesi;', 'anche', ""l'opzione"", '5', 'è', 'falsa,', 'poiché', 'il', 'danno', 'non', 'è', 'dovuto', 'agli', 'immunocomplessi', 'circolanti,', 'ma', 'agli', 'anticorpi', 'depositati', 'nella', 'membrana', 'basale', 'glomerulare.'], ['Rimane', ""l'opzione"", '2:', 'come', 'già', 'detto,', 'il', 'trattamento', 'sarebbe', 'una', 'combinazione', 'di', 'corticosteroidi,', 'ciclofosfamide', 'e', 'plasmaferesi.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'senza', 'assumere', 'alcun', 'farmaco', 'e', 'senza', 'alcuna', 'anamnesi', 'rilevante.'], ['In', 'effetti,', ""l'esame"", 'fisico', 'mostra', 'uno', 'stadio', 'di', 'Tanner', 'IV,', 'senza', 'crescita', 'di', 'peli', 'pubici', 'o', 'ascellari.'], ['I', 'genitali', 'esterni', 'sono', 'normali.'], [""L'ecografia"", 'rivela', 'un', 'utero', 'piccolo', 'e', 'la', 'radiologia', 'rivela', ""un'età"", 'ossea', 'di', '3', 'anni.'], ['Quale', 'atteggiamento', 'adottare?'], ['1-', 'Controlli', 'ogni', '3-4', 'mesi,', 'poiché', 'si', 'tratta', 'di', 'una', 'condizione', 'temporanea', 'che', 'spesso', 'si', 'risolve', 'da', 'sola.'], ['2-', 'Biopsia', 'del', 'seno.'], ['3-', 'Mammografia.'], ['4-', 'Somministrazione', 'di', 'analoghi', 'del', 'GnRh.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '1'], ['Questa', 'domanda', 'è', 'troppo', 'sviluppata', 'per', 'i', 'normali', 'esami', 'complementari...', 'Sembra', 'che', 'vogliano', 'presentarci', 'una', 'pubertà', 'precoce', '(o', 'un', 'telarca', 'prematuro)', 'ma', 'non', 'forniscono', 'alcun', 'dato', 'analitico', 'e', 'i', 'dati', 'ecografici', 'sono', 'ambigui', '(si', 'dovrebbe', 'supporre', 'che', 'con', 'un', 'utero', 'piccolo', 'si', 'riferiscano', 'a', 'un', 'utero', 'prepuberale,', 'ma', 'non', 'forniscono', 'alcun', 'dato', 'sulle', 'dimensioni', 'delle', 'ovaie).'], ['Ci', 'viene', 'presentato', 'il', 'caso', 'di', 'una', 'bambina', 'di', 'tre', 'anni', 'con', 'un', 'avanzato', 'sviluppo', 'del', 'seno,', 'in', 'linea', 'di', 'massima', 'senza', 'alcuna', 'causa', 'associata', '(in', 'linea', 'di', 'massima', 'non', 'assume', 'farmaci', 'che', 'potrebbero', 'aumentare', 'il', 'livello', 'di', 'estrogeni', 'nel', 'sangue,', 'non', 'sembra', 'usare', 'creme', 'per', 'il', 'corpo', 'e', 'non', 'sembra', 'avere', ""un'assunzione"", 'significativa', 'di', 'carne', 'di', 'pollo).'], ['Se', 'seguiamo', 'lo', 'schema', 'diagnostico', 'in', 'caso', 'di', 'telarca', 'precoce', 'o', 'di', 'sospetta', 'pubertà', 'precoce,', 'vengono', 'richieste', ""l'età"", 'ossea', 'e', ""l'ecografia"", 'addominale', ""(l'EO"", 'non', 'è', 'avanzato', 'come', 'avviene', 'nella', 'pubertà', 'precoce,', 'e', 'si', 'presume', 'che', 'per', 'utero', 'piccolo', 'si', 'intenda', 'un', 'utero', 'prepuberale);', 'in', 'base', 'agli', 'esami', 'complementari', 'che', 'ci', 'vengono', 'forniti,', 'non', 'sembra', 'trattarsi', 'di', 'pubertà', 'precoce,', 'se', 'non', 'per', 'i', 'reperti', 'clinici', '(Tanner', 'IV).'], ['A', 'rigore,', 'senza', 'dati', 'ormonali', 'analitici,', 'sembra', 'che', 'si', 'possa', 'scegliere', ""l'opzione"", '1,', 'con', 'la', 'necessità', 'di', 'un', 'attento', 'monitoraggio', 'della', 'ragazza.'], ['Se', 'diamo', 'per', 'scontati', 'tutti', 'i', 'dati', 'di', 'cui', 'sopra,', 'potremmo', 'escludere', ""l'opzione"", '4,', 'che', 'sarebbe', 'il', 'trattamento', 'della', 'pubertà', 'precoce', 'centrale.'], ['Per', 'quanto', 'riguarda', ""l'opzione"", 'della', 'mammografia,', ""l'ecografia"", 'mammaria', 'è', 'utilizzata', 'in', 'pediatria', 'e', 'in', 'questo', 'caso', 'sarebbe', 'indicata', 'se', 'ci', 'venisse', 'segnalata', ""un'asimmetria"", 'del', 'seno', ""(l'opzione"", '3', 'è', 'esclusa).'], ['La', 'biopsia', 'mammaria', 'sarebbe', 'indicata', 'solo', 'in', 'presenza', 'di', 'segnali', 'di', 'allarme.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +238_145,"[['QUESTION', 'TYPE:', 'NEUROLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '40', 'anni', 'ha', 'consultato', 'per', 'circa', '20', 'episodi', 'al', 'giorno', 'di', 'intenso', 'dolore', 'perioculare', 'sinistro', 'della', 'durata', 'di', '15', 'minuti,', 'accompagnato', 'da', 'intensa', 'lacrimazione', 'e', 'rinorrea.'], [""L'esame"", 'e', 'la', 'risonanza', 'magnetica', 'sono', 'normali.'], ['Il', 'loro', 'trattamento', 'di', 'scelta', 'sarebbe:'], ['1-', 'Indometacina.'], ['2-', 'Lamotrigina.'], ['3-', 'Verapamil.'], ['4-', 'Prednisone.'], ['5-', 'Carbonato', 'di', 'litio.'], ['RISPOSTA', 'CORRETTA:', '1'], ['In', 'questa', 'domanda', 'ci', 'viene', 'presentato', 'un', 'caso', 'per', 'dedurre', 'una', 'diagnosi', 'e', 'quindi', 'indicare', 'il', 'trattamento', 'di', 'scelta.'], ['Sia', 'le', 'caratteristiche', 'del', 'caso', 'che', 'le', 'risposte', 'suggeriscono', 'che', 'si', 'tratta', 'di', 'una', 'cefalea', 'trigemino-autonomica', '(dolore', 'intenso', 'e', 'perioculare', 'con', 'lacrimazione', 'e', 'rinorrea).'], [""L'idea"", 'è', 'quella', 'di', 'fare', 'una', 'diagnosi', 'differenziale', 'innanzitutto', 'tra', 'una', 'cefalea', 'a', 'grappolo', '(il', 'cui', 'trattamento', 'comprende', 'le', 'risposte', '2,', '3,', '4', 'e', '5),', ""un'emicrania"", 'parossistica', '(il', 'cui', 'trattamento', 'di', 'scelta', 'è', ""l'indometacina"", 'della', 'risposta', '1)', 'e', 'una', 'SUNCT', '(cefalea', 'unilaterale', 'nevralgiforme', 'con', 'iniezione', 'congiuntivale', 'e', 'lacrimazione).'], ['La', 'cefalea', 'a', 'grappolo', 'prevale', 'nei', 'maschi', 'e', 'può', 'avere', 'una', 'durata', 'variabile', 'da', '15', 'a', '180', 'minuti,', 'da', 'una', 'volta', 'ogni', '2', 'giorni', 'fino', 'a', '8', 'volte', 'al', 'giorno.'], [""L'emicrania"", 'parossistica', 'predomina', 'nelle', 'donne,', 'con', 'episodi', 'di', 'dolore', 'simili', 'alla', 'cefalea', 'a', 'grappolo,', 'ma', 'di', 'durata', 'più', 'breve', '(2-30', 'minuti)', 'e', 'frequenza', 'più', 'elevata', '(5-30', 'episodi', 'al', 'giorno).'], ['Nella', 'SUNCT,', 'le', 'crisi', 'sono', 'molto', 'più', 'brevi,', 'durano', 'pochi', 'secondi', '(5-240', 'secondi)', 'e', 'sono', 'solitamente', 'refrattarie', 'al', 'trattamento.'], ['Pertanto,', 'la', 'diagnosi', 'sarebbe', 'emicrania', 'parossistica', 'e', 'il', 'trattamento', 'di', 'scelta', 'è', ""l'indometacina"", '(e', 'la', 'risposta', 'è', 'un', 'criterio', 'diagnostico).'], ['Quindi', 'la', 'risposta', 'corretta', 'è', '1', '(Indometacina).'], ['Tutti', 'i', 'dati', 'forniti', 'si', 'basano', 'sui', 'criteri', 'diagnostici', ""dell'International"", 'Headache', 'Society.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['O', 'O', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O']]" +47_157,"[['QUESTION', 'TYPE:', 'PEDIATRIA'], ['CLINICAL', 'CASE:'], ['Un', 'bambino', 'di', '6', 'anni', 'è', 'arrivato', 'in', 'clinica', 'accompagnato', 'dal', 'monitore', 'di', 'un', 'centro', 'di', 'accoglienza', 'del', 'nostro', 'quartiere', 'a', 'causa', 'di', 'un', 'tumore', 'doloroso', 'di', '3', 'cm', 'di', 'diametro', 'alla', 'palpazione', ""nell'area"", 'occipitale', 'destra', 'del', 'cuoio', 'capelluto.'], ['Presenta', 'alopecia', 'in', ""quest'area"", 'e', '3', 'linfoadenomegalie', 'di', 'consistenza', 'piuttosto', 'dura', 'nella', 'regione', 'cervicale', 'posteriore', 'destra.'], ['Quale', 'sarebbe', 'il', 'trattamento', 'più', 'appropriato?'], ['1-', 'Incisione', 'e', 'drenaggio.'], ['2-', 'Mupirocina', 'topica.'], ['3-', 'Griseofulvina', 'per', 'via', 'orale.'], ['4-', 'Cefazolina', 'intravenosa.'], ['5-', 'Chetoconazolo', 'topico.'], ['RISPOSTA', 'CORRETTA:', '3'], ['La', 'risposta', 'corretta', 'è', '3'], ['Se', 'non', 'sbaglio', 'sta', 'descrivendo', 'un', 'kerion', 'di', 'Celso', 'per', 'il', 'quale', 'il', 'trattamento', 'di', 'scelta', 'è', 'la', 'griseofulvina', 'orale.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +381_139,"[['QUESTION', 'TYPE:', 'NEUROLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '70', 'anni', 'con', 'anamnesi', 'di', 'anoressia,', 'perdita', 'di', 'peso,', 'fastidio', 'alla', 'muscolatura', 'e', 'alle', 'articolazioni', 'prossimali', 'e', 'dolore', 'alla', 'regione', 'temporo-mandibolare', 'si', 'presenta', 'al', 'pronto', 'soccorso', 'per', 'una', 'perdita', 'unilaterale', 'della', 'vista', '(movimento', 'della', 'mano),', 'di', 'insorgenza', 'improvvisa', 'e', 'non', 'dolorosa', '(difetto', 'pupillare', 'afferente).', 'Quale', 'esame', 'richiedereste', 'in', 'primo', 'luogo', 'a', 'scopo', 'diagnostico?'], ['1-', 'Puntura', 'lombare.'], ['2-', 'Proteina', 'C-Reattiva.'], ['3-', 'Angiografia', 'a', 'risonanza', 'magnetica.'], ['4-', 'Ecografia', 'carotidea.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '2'], ['Ci', 'viene', 'presentato', 'un', 'caso', 'di', 'amaurosi', 'monoculare', 'con', 'profilo', 'vascolare,', 'sempre', 'in', 'una', 'donna', 'anziana', 'con', 'una', 'storia', 'di', 'perdita', 'di', 'peso', 'e', 'quelli', 'che', 'sembrano', 'essere', 'sintomi', 'di', 'claudicatio', 'mandibolare', 'e', 'polimialgia', 'reumatica,', 'quindi', 'la', 'prima', 'causa', 'da', 'considerare', 'è', ""l'arterite"", 'a', 'cellule', 'giganti', 'come', 'causa', 'della', 'NOIA,', 'quindi', 'tra', 'le', 'opzioni', 'quella', 'corretta', 'sarebbe', ""l'opzione"", '2'], ['Considereremmo', '4', 'se', 'ci', 'venisse', 'segnalata', 'una', 'NOIA', 'ma', 'con', 'caratteristiche', 'non', 'arteritiche', '(senza', 'tutta', 'la', 'sintomatologia', 'di', 'accompagnamento).']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +32_64,"[['QUESTION', 'TYPE:', 'NEUROLOGIA', 'E', 'NEUROCHIRURGIA'], ['CLINICAL', 'CASE:'], ['In', 'un', 'paziente', 'con', 'diagnosi', 'di', 'epilessia', 'che', 'presenta', 'episodi', 'di', 'mancata', 'risposta', 'a', 'stimoli', 'esterni,', 'movimenti', 'irregolari', 'di', 'tutti', 'e', 'quattro', 'gli', 'arti,', 'occhi', 'chiusi,', 'pianto', 'e', 'movimenti', 'pelvici,', 'della', 'durata', 'di', 'cinque-venti', 'secondi', 'e', 'non', 'rispondenti', 'al', 'trattamento', 'con', 'farmaci', 'antiepilettici,', 'qual', 'è', 'lo', 'studio', 'complementare', 'che', 'più', 'probabilmente', 'chiarirà', 'la', 'diagnosi?'], ['1-', 'Monitoraggio', 'video-EEG', 'per', 'la', 'diagnosi', 'di', 'pseudo-crisi', '(crisi', 'psicogene).'], ['2-', 'Holter', 'ECG', 'per', 'la', 'diagnosi', 'di', 'cardiopatia', 'aritmica.'], ['3-', 'EEG', 'di', 'routine', 'per', 'la', 'diagnosi', 'del', 'tipo', 'di', 'epilessia', '(generalizzata', 'o', 'focale).'], ['4-', 'Risonanza', 'magnetica', 'cerebrale', 'per', 'individuare', 'lesioni', 'epilettogene', '(displasia', 'corticale,', 'tumore,', 'sclerosi', 'temporale', 'mediale).'], ['5-', 'Determinazione', 'della', 'glicemia', 'capillare', 'per', 'la', 'diagnosi', 'di', 'ipoglicemia.'], ['RISPOSTA', 'CORRETTA:', '1'], ['Risposta', 'corretta', '1:', 'Il', 'quadro', 'descritto', 'è', 'altamente', 'suggestivo', 'di', 'pseudocrisi', 'con', 'movimenti', 'asincroni', 'degli', 'arti,', 'movimenti', 'pelvici,', 'pianto', 'e', 'scarsa', 'risposta', 'ai', 'farmaci', 'antiepilettici.']]","[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +106_135,"[['QUESTION', 'TYPE:', 'GENETICA', 'E', 'IMMUNOLOGIA'], ['CLINICAL', 'CASE:'], ['Bambino', 'di', '2', 'anni.'], [""L'anamnesi"", 'personale', 'comprende:', '3', 'episodi', 'di', 'otite', 'media', 'acuta,', '1', 'meningite', 'meningococcica', 'e', '2', 'polmoniti', '(una', 'al', 'lobo', 'medio', 'e', 'una', 'al', 'lobo', 'superiore', 'sinistro).'], ['È', 'stato', 'ricoverato', '3', 'volte', 'per', 'porpora', 'trombocitopenica', '(in', 'tre', 'occasioni', 'gli', 'anticorpi', 'antiaggreganti', 'piastrinici', 'erano', 'negativi', 'e', 'il', 'midollo', 'osseo', 'mostrava', 'megacariociti', 'normali).'], ['Diversi', 'ragazzi', 'della', 'famiglia', 'materna', 'erano', 'morti', 'in', 'età', 'infantile', 'a', 'causa', 'di', 'malattie', 'infettive.'], [""L'esame"", 'fisico', 'ha', 'rivelato', 'lesioni', 'tipiche', 'della', 'dermatite', 'atopica.'], ['Lo', 'studio', 'immunologico', 'ha', 'mostrato', 'una', 'leggera', 'diminuzione', 'delle', 'sottopopolazioni', 'di', 'linfociti', 'T;', 'IgA', 'e', 'IgE', 'elevate;', 'IgM', 'e', 'IgG', 'ridotte', 'al', 'limite', 'inferiore', 'della', 'norma.'], ['Qual', 'è', 'la', 'diagnosi', 'più', 'probabile?'], ['1-', 'Sindrome', 'di', 'Wiskott-Aldrich.'], ['2-', 'Sindrome', 'da', 'iper', 'IgE.'], ['3-', 'Ipogammaglobulinemia', 'transitoria', ""dell'infanzia.""], ['4-', 'Immunodeficienza', 'combinata', 'grave', 'legata', ""all'X.""], ['5-', 'Immunodeficienza', 'comune', 'variabile.'], ['RISPOSTA', 'CORRETTA:', '4'], ['Per', 'rispondere', 'correttamente', 'a', 'questa', 'domanda,', 'è', 'necessario', 'notare', 'che', 'tra', 'i', 'sintomi', 'descritti', 'vi', 'sono', 'i', 'seguenti:', '-', 'Bambino', 'di', '2', 'anni.'], ['-', 'Infezioni', 'otorinolaringoiatriche.'], ['-', 'Infezioni', 'polmonari.'], ['-', 'Ricoveri', 'ospedalieri.'], ['-', 'PTI.'], ['-', 'Storia', 'familiare', 'di', 'infezioni', 'con', 'decessi', 'per', 'infezioni', 'nei', 'maschi', '(famiglia', 'materna).'], ['-', 'Dermatite', 'atopica.'], ['Tutti', 'questi', 'dati,', 'insieme', 'a', 'quelli', 'analitici,', 'descrivono', ""un'immunodeficienza"", 'che,', ""dall'anamnesi"", 'familiare-materna,', 'sembra', 'essere', 'legata', ""all'X,"", 'dal', 'momento', 'che', 'diversi', 'maschi', 'sono', 'morti', 'per', 'una', 'condizione', 'clinica', 'simile', '(il', 'padre', 'del', 'paziente', 'ha', 'contribuito', 'con', 'il', 'cromosoma', 'Y,', 'la', 'madre', 'con', 'il', 'cromosoma', 'X).'], ['Tra', 'le', 'immunodeficienze', 'X-linked', ""c'è"", 'la', 'sindrome', 'di', 'Wiskott-Aldrich,', ""un'entità"", 'descritta', 'con', 'una', 'triade', 'iniziale', 'di', 'sintomi', 'che', 'consiste', 'in', 'emorragie', '(tipiche', 'MA', 'assenti', 'nel', 'caso:', 'forti', 'emorragie', 'dopo', 'la', 'circoncisione,', 'diarrea', 'sanguinolenta),', 'infezioni', 'ricorrenti', 'ed', 'eczema.'], ['Oltre', 'alla', 'trombocitopenia,', 'sono', 'a', 'maggior', 'rischio', 'di', 'fenomeni', 'autoimmuni', 'e', 'neoplasie', 'linfoidi.'], [""L'opzione"", 'Iper-IgE', 'manca', 'di', 'dati', 'clinici', 'molto', 'caratteristici,', 'come', 'le', 'alterazioni', 'ossee', 'e', 'le', 'lesioni', 'cutanee,', 'che', 'non', 'sono', 'dermatite', 'atopica,', 'in', 'quanto', 'seguono', 'un', 'modello', 'diverso', '(eruzione', 'papulopustolosa', 'sul', 'viso', 'e', 'sul', 'cuoio', 'capelluto).'], [""L'opzione"", ""dell'ipogammaglobulinemia"", 'transitoria', ""dell'infanzia"", 'e', 'le', 'comuni', 'immunodeficienze', 'combinate', 'gravi', 'e', 'variabili', 'sono,', 'tra', 'le', 'altre', 'caratteristiche,', 'la', 'mancanza', 'della', 'determinazione', 'delle', 'immunoglobuline', 'G', 'e', 'M,', 'che', 'sono', 'al', 'limite', 'inferiore,', 'ma', ""all'interno"", 'del', 'range', 'di', 'normalità.']]","[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'ha', 'mostrato', 'una', 'glicemia', 'di', '96', 'mg/dL,', 'una', 'natremia', 'di', '148', 'mEq/L', 'e', ""un'osmolalità"", 'plasmatica', 'di', '309', 'mOsm/kg', 'con', ""un'osmolalità"", 'urinaria', 'di', '89', 'mOsmlkg.'], ['Quale', 'test', 'diagnostico', 'deve', 'essere', 'eseguito', 'successivamente?'], ['1-', 'Test', 'di', 'infusione', 'di', 'soluzione', 'salina', 'ipertonica', 'per', 'la', 'determinazione', 'seriale', ""dell'ormone"", 'antidiuretico.'], ['2-', 'Test', 'di', 'disidratazione', '(test', 'di', 'Miller).'], ['3-', 'Somministrazione', 'di', 'desmopressina', 'con', 'monitoraggio', 'seriale', ""dell'osmolalità"", 'delle', 'urine.'], ['4-', 'Determinazione', ""dell'ormone"", 'antidiuretico', 'nel', 'plasma.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Ci', 'incontriamo', 'davanti', 'alla', 'poliuria.'], ['Inizialmente', 'abbiamo', 'escluso', 'il', 'diabete', 'mellito', '(il', 'nostro', 'paziente', 'ha', 'una', 'glicemia', 'normale', 'di', '96', 'mgr/dl).'], ['I', 'dati', 'analitici', 'suggeriscono', 'un', 'diabete', 'insipido', '(osm', 'plasmatico', 'elevato', 'con', 'osm', 'urinario', 'basso).'], ['Occorre', 'ora', 'distinguere', 'tra', 'diabete', 'insipido', 'centrale', '(mancanza', 'di', 'ADH)', 'e', 'diabete', 'insipido', 'nefrogenico', ""(l'ADH"", 'non', 'esercita', 'la', 'sua', 'azione', 'a', 'livello', 'renale).'], ['Ciò', 'si', 'ottiene', 'con', 'il', 'test', 'della', 'vasopressina', '(somministrazione', 'endovenosa', 'di', 'ADH', 'e', 'rimisurazione', ""dell'osmolarità"", 'urinaria).'], ['Pertanto,', 'la', 'risposta', 'corretta', 'è', ""l'opzione"", '3']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +8_232,"[['QUESTION', 'TYPE:', 'DIGESTIVO'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '52', 'anni', 'si', 'è', 'consultata', 'per', 'aver', 'notato', 'una', 'colorazione', 'giallastra', 'delle', 'congiuntive', 'durante', 'la', 'settimana', 'precedente.'], ['Non', 'riferisce', 'alcun', 'comportamento', 'sessuale', 'a', 'rischio', 'o', 'storia', 'epidemiologica', 'di', 'rischio', 'per', ""l'epatite"", 'virale.'], ['Non', 'consuma', 'alcolici', 'o', 'farmaci', 'epatotossici.'], ['Riferisce', 'una', 'storia', 'di', 'un', 'anno', 'di', 'prurito', 'generalizzato,', 'astenia,', 'secchezza', 'delle', 'fauci', 'e', 'assenza', 'di', 'lacrimazione', 'di', 'causa', 'non', 'identificata.'], ['Resto', ""dell'anamnesi"", 'senza', 'dati', 'patologici.'], [""L'esame"", 'fisico', 'ha', 'rivelato', 'lesioni', 'da', 'grattamento,', 'ittero', 'congiuntivale', 'ed', 'epatomegalia', 'non', 'dolorosa.'], ['Ha', 'fornito', 'gli', 'esami', 'del', 'sangue', 'eseguiti', 'nella', 'sua', 'azienda', 'con', 'i', 'seguenti', 'risultati', 'patologici:', 'Bilirubina', '3', 'mg/dl,', 'FA', '400', 'UI/', 'VSG', '40mm', '1', 'ora.'], ['Indicare', 'quale', 'sarebbe', 'la', 'raccomandazione', 'più', 'appropriata', 'per', 'stabilire', 'la', 'diagnosi', 'eziologica', 'della', 'condizione', 'del', 'paziente:'], ['1-', 'Anticorpi', 'antimitocondriali.'], ['2-', 'Studio', 'del', 'metabolismo', 'del', 'Fe.'], ['3-', 'Studio', 'del', 'metabolismo', 'del', 'rame.'], ['4-', 'Risonanza', 'magnetica', 'del', 'fegato.'], ['5-', 'Sierologia', 'del', 'virus', 'B', 'e', 'C.'], ['RISPOSTA', 'CORRETTA:', '1'], ['Cirrosi', 'biliare', 'primaria', 'immagine', 'del', 'libro,', 'del', 'tipo', 'che', 'non', 'si', 'verifica', 'nella', 'vita', 'reale.'], ['La', 'diagnosi', 'verrebbe', 'praticamente', 'fatta', 'con', ""l'AMA"", '(1).'], ['Con', '2', 'escludiamo', ""l'emocromatosi,"", 'con', '3', 'escludiamo', 'la', 'malattia', 'di', 'Wilson.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +621_60,"[['QUESTION', 'TYPE:', 'OFTALMOLOGIA', '(ECTOPICA)'], ['CLINICAL', 'CASE:'], ['Un', 'paziente', 'di', '20', 'anni', 'si', 'è', 'recato', 'al', 'pronto', 'soccorso', 'dopo', 'un', 'incidente', 'in', 'bicicletta', 'con', 'trauma', 'facciale.'], ['È', 'stata', 'eseguita', 'una', 'TC', 'cranica', 'che', 'ha', 'mostrato', 'una', 'frattura', 'del', 'terzo', 'medio', 'della', 'faccia', 'con', 'interessamento', 'della', 'regione', 'orbito-malare.'], ['Una', 'delle', 'complicazioni', 'più', 'frequenti', 'di', 'questo', 'tipo', 'di', 'frattura', 'è', 'il', 'dolore:'], ['1-', 'Anchilosi', 'temporo-mandibolare.'], ['2-', 'Malocclusione', 'dentale.'], ['3-', 'Pseudoartrosi', 'naso-etmoidale.'], ['4-', 'Enoftalmo.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '4'], ['Le', 'fratture', 'della', 'faccia', 'media', 'nella', 'regione', 'orbito-malare', 'possono', 'coinvolgere', 'il', 'pavimento', 'e,', 'in', 'misura', 'minore,', 'la', 'parete', 'laterale', ""dell'orbita.""], ['Supponendo', 'quindi', 'che', 'ci', 'venga', 'chiesto', 'quale', 'sia', 'una', 'delle', 'complicanze', 'più', 'frequenti', 'del', 'pavimento', ""dell'orbita,"", 'vanno', 'sempre', 'evidenziate', 'due', 'complicanze', 'che', 'possono', 'indicare', 'un', 'trattamento', 'chirurgico,', 'anche', 'urgente:', 'la', 'diplopia,', 'dovuta', 'alla', 'dislocazione', 'del', 'muscolo', 'retto', 'inferiore', 'verso', 'il', 'seno', 'mascellare', 'sottostante', '(e', 'persino', 'al', 'suo', 'intrappolamento);', 'e', ""l'enoftalmo,"", 'che', 'può', 'portare', 'ad', 'altre', 'complicanze', 'associate', 'a', 'medio', 'e', 'lungo', 'termine,', 'come', 'la', 'pseudoptosi', 'palpebrale', 'superiore', 'dovuta', 'alla', 'perdita', 'di', 'volume', 'orbitale', '(opzione', '4', 'corretta).'], [""L'anchilosi"", 'temporo-mandibolare', 'non', 'viene', 'considerata', 'perché,', 'sebbene', 'relativamente', 'vicina', 'alla', 'cavità', 'orbitale,', 'non', 'fa', 'parte', 'del', 'complesso', 'orbito-malare', '(opzione', '1', 'scartata).'], ['Il', 'coinvolgimento', 'del', 'mascellare', 'può', 'provocare', 'una', 'malocclusione', 'dentale,', 'ma', 'di', 'solito', 'si', 'verifica', 'nelle', 'fratture', 'situate', 'più', 'in', 'basso', 'rispetto', 'alla', 'cavità', 'orbitale', '(opzione', '2', 'scartata).'], ['Le', 'fratture', 'naso-etmoidali', 'sono', 'considerate', 'fratture', 'della', 'faccia', 'media,', 'ma', 'le', 'ossa', 'del', 'naso', 'sono', 'situate', 'più', 'anteriormente', 'al', 'bordo', 'orbitale', 'mediale', 'e', 'quindi', 'al', 'di', 'fuori', ""dell'orbita"", '(opzione', '3', 'scartata).']]","[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim']]" +470_138,"[['QUESTION', 'TYPE:', 'CHIRURGIA', 'ORTOPEDICA', 'E', 'TRAUMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Donna', 'di', '73', 'anni', 'con', 'storia', 'di', 'obesità,', 'diabete', 'mellito', 'di', 'tipo', '2,', 'ipertensione', 'e', 'dislipidemia.'], ['Consultazione', 'per', 'dolore', 'insopportabile', 'al', 'ginocchio', 'destro', 'da', '5', 'giorni,', 'senza', 'traumi', 'precedenti.'], ['Esame:', 'ginocchio', 'globoso,', 'varismo', 'moderato,', 'estensione', 'e', 'flessione', 'limitate', 'dal', 'dolore,', 'dolore', 'mediale', 'diffuso.'], ['La', 'radiografia', 'mostra', 'osteofiti', 'e', 'un', 'lieve', 'impingement', ""dell'interlinea"", 'mediale.'], ['Quale', 'sarebbe', 'la', 'loro', 'gestione', 'iniziale?'], ['1-', 'Spiegazione', 'della', 'diagnosi,', 'riposo', 'relativo,', 'paracetamolo', '1g/8h', 'più', 'metamizolo', '500', 'mg/', '8', 'h', 'naprossene', 'di', 'soccorso.'], ['2-', 'Invio', 'preferenziale', 'agli', 'ambulatori', 'di', 'traumatologia', 'per', 'la', 'valutazione', 'delle', 'protesi', 'totali', 'cementate.'], ['3', 'Invio', 'preferenziale', 'a', 'pazienti', 'ambulatoriali', 'di', 'Traumatologia', 'per', 'valutare', 'lo', 'sbrigliamento', 'artroscopico.'], ['4-', 'Richiesta', 'di', 'RM', 'preferenziale', 'per', 'la', 'valutazione', 'di', 'meniscopatia,', 'cisti', 'di', 'Baker', 'e/o', 'tendinite.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '1'], ['Descrivono', 'una', 'crisi', 'di', 'dolore', 'acuto', 'in', 'un', 'paziente', 'con', 'gonartrosi.'], ['In', 'questa', 'situazione,', 'il', 'primo', 'passo', 'è', 'quello', 'di', 'risolvere', 'la', 'crisi', 'di', 'dolore', 'e', 'considerare', 'un', 'trattamento', 'conservativo', 'appropriato', 'per', ""l'osteoartrite"", '(1', 'corretto).'], [""L'artroplastica"", 'del', 'ginocchio', 'non', 'viene', 'presa', 'in', 'considerazione', ""all'inizio,"", 'quindi', 'il', 'punto', '2', 'è', 'falso.'], ['Non', 'ci', 'dicono', 'che', 'una', 'clinica', 'infettiva', 'sospetti', ""un'artrite"", 'che', 'giustifichi', 'lo', 'sbrigliamento', 'e', 'il', 'lavaggio,', 'quindi', 'il', 'punto', '3', 'è', 'falso.'], ['In', 'un', 'paziente', 'con', 'gonartrosi', 'ci', 'sarà', 'sempre', 'una', 'meniscopatia,', 'che', 'fa', 'parte', 'dei', 'cambiamenti', 'degenerativi.'], ['La', 'cisti', 'di', 'Baker', 'ci', 'interessa', 'solo', 'in', 'caso', 'di', 'grave', 'crisi', 'di', 'dolore', 'nella', 'diagnosi', 'differenziale', 'con', 'la', 'trombosi', 'profonda', 'e', 'viene', 'valutata', 'con', 'un', 'ecodoppler;', 'in', 'caso', 'di', 'gonartrosi', 'non', 'ha', 'alcun', 'valore', 'rilevare', 'una', 'cisti', 'di', 'Baker.'], ['La', 'tendinite', 'si', 'diagnostica', 'con', 'un', 'esame,', 'non', 'con', 'la', 'risonanza', 'magnetica.'], ['Pertanto,', 'il', 'punto', '4', 'è', 'falso.']]","[['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 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'tramite', 'cateterismo.'], ['Le', 'urine', 'mostrano', 'leucocituria', '++,', 'ematuria', '++', 'e', 'nitriti', '++', 'e', 'le', 'urine', 'presentano', 'bacilli', 'Gram-negativi.'], [""Nell'esame"", 'del', 'sangue', 'non', ""c'è"", 'leucocitosi', 'e', 'la', 'proteina', 'C-reattiva', 'è', 'di', '50', 'mg/l.'], ['Il', 'medico', 'curante', 'vi', 'dice', 'che', 'il', 'bambino', 'non', 'deve', 'essere', 'ricoverato', 'e', 'di', 'prescrivere', 'un', 'antibiotico', 'orale.'], ['Indicare', 'il', 'trattamento', 'antibiotico', 'empirico', 'meno', 'appropriato', 'in', 'questo', 'caso:'], ['1-', 'Amoxicilina.'], ['2-', 'Acido', 'amoxicillina-clavulanico.'], ['3-', 'Cefuroxima-axetil.'], ['4-', 'Cotrimoxazolo.'], ['5-', 'Cefixime.'], ['RISPOSTA', 'CORRETTA:', '1'], ['Tutti', 'gli', 'altri', 'farmaci', 'sono', 'una', 'buona', 'scelta', 'nelle', 'UTI', 'da', 'bacilli', 'grandi', 'negativi', '(molto', 'probabilmente', 'E.', 'coli).'], ['La', 'presenza', 'di', 'leucociti', '+', 'nitriti', 'nelle', 'urine', 'è', 'altamente', 'suggestiva', 'di', 'UTI.'], ['Se', ""l'esame"", 'di', 'Gram', 'delle', 'urine', 'rileva', 'batteri', 'G,', 'è', 'probabile', 'che', 'si', 'tratti', 'di', ""un'infezione"", 'da', 'Escherichia', 'coli.'], ['Molti', 'E', 'coli', 'sono', 'resistenti', ""all'amoxicillina.""]]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'è', 'esclusa,', 'perché', 'di', 'solito', 'si', 'verifica', 'nei', 'pazienti', 'più', 'anziani,', 'anche', 'se', 'un', 'paziente', 'con', 'miopia', 'magna', 'può', 'presentare', 'una', 'degenerazione', 'maculare', 'miopica', '(con', 'un', 'quadro', 'clinico', 'simile', ""all'AMD,"", 'ma', 'con', 'una', 'patologia', 'diversa).'], ['Un', 'distacco', 'posteriore', 'del', 'vitreo', '(PVD)', 'di', 'solito', 'non', 'è', 'molto', 'sintomatico,', 'in', 'quanto', 'produce', 'miodesopsie', 'ma', 'non', 'perdita', 'della', 'vista', 'o', 'dolore;', 'tuttavia,', 'alcuni', 'PVD', 'sono', 'di', 'natura', 'emorragica,', 'in', 'quanto', 'i', 'vasi', 'vengono', 'sottoposti', 'a', 'trazione,', 'producendo', ""un'emorragia"", 'vitreale', 'che', 'causerebbe', 'la', 'perdita', 'della', 'vista.'], ['In', 'ogni', 'caso,', 'data', ""l'anamnesi"", 'di', 'miopia', 'magna', 'e', 'di', 'precedenti', 'interventi', 'chirurgici', 'intraoculari,', 'la', 'prima', 'diagnosi', 'da', 'escludere', 'sarebbe', 'il', 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'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O']]" +279_32,"[['QUESTION', 'TYPE:', 'ANATOMIA', 'PATOLOGICA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '59', 'anni', 'ha', 'presentato', 'una', 'diarrea', 'acquosa', 'cronica', 'di', '4', 'mesi.'], [""All'endoscopia,"", 'la', 'mucosa', 'non', 'presentava', 'caratteristiche', 'rilevanti.'], ['In', 'particolare,', 'non', 'sono', 'state', 'osservate', 'ulcere', 'o', 'aree', 'friabili.'], ['È', 'stata', 'eseguita', 'una', 'biopsia', 'del', 'colon', 'trasverso.'], [""L'istopatologia"", 'ha', 'rivelato', ""un'area"", 'ispessita', 'sotto', ""l'epitelio"", 'di', 'rivestimento', 'superficiale,', 'più', 'evidente', 'con', 'la', 'tecnica', 'della', 'tricromia', 'di', 'Masson,', 'che', 'comporta', 'atrofia', 'e', 'denudazione', 'epiteliale.'], ['È', 'stato', 'inoltre', 'riscontrato', 'un', 'chiaro', 'aumento', 'della', 'densità', 'dei', 'linfociti', 'intraepiteliali.'], ['La', 'diagnosi', 'della', 'lesione', 'intestinale', 'è?'], ['1-', 'Colite', 'ulcerosa', 'cronica.'], ['2-', 'Colite', 'pseudomembranosa.'], ['3-', 'Colite', 'collagena.'], ['4-', 'Malattia', 'di', 'Crohn', 'fibrosa.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['In', 'questo', 'caso,', 'la', 'presenza', 'di', 'un', 'ispessimento', 'dello', 'strato', 'di', 'collagene', 'subepiteliale,', 'più', 'evidente', 'con', 'la', 'tricromia', 'di', 'Masson', '(una', 'speciale', 'colorazione', 'che', 'permette', 'di', 'differenziare', 'le', 'fibre', 'di', 'collagene),', 'è', 'patognomonica', 'di', 'colite', 'collagenosa.'], [""L'atrofia"", 'e', 'la', 'denudazione', 'epiteliale', 'sono', 'caratteristiche', 'di', 'questa', 'malattia,', 'che', 'di', 'solito', 'non', 'causa', 'alterazioni', 'macroscopiche', 'della', 'mucosa.'], [""Un'aumentata"", 'densità', 'di', 'linfociti', 'intraepiteliali', 'e', ""l'assenza"", 'di', 'alterazioni', 'architettoniche', 'delle', 'cripte', '(caratteristiche', 'della', 'colite', 'ulcerosa', 'e', 'della', 'malattia', 'di', 'Crohn)', 'supportano', 'questa', 'diagnosi.']]","[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'al', 'minuto,', 'la', 'ferita', 'presenta', 'un', 'leggero', 'gonfiore', 'senza', 'pus.'], ['Quale', 'delle', 'seguenti', 'azioni', 'è', 'più', 'appropriata', 'in', 'questo', 'momento?'], ['1-', 'Inviare', ""all'ospedale"", 'per', 'la', 'vaccinazione', 'antirabbica', 'e', 'antitetanica', 'e', 'tenere', 'sotto', 'osservazione.'], ['2-', 'Pulire', 'la', 'ferita', 'e', 'somministrare', 'ganunaglobulina', 'aspecifica', 'per', 'via', 'intramuscolare.'], ['3-', 'Somministrare', '400', 'mg', 'di', 'moxifloxacina', 'per', 'via', 'orale', 'e', 'inviare', 'in', 'ospedale.'], ['4-', 'Somministrare', 'clindamicina', '600', 'mg', 'per', 'via', 'orale', 'ogni', '8', 'ore', 'e', 'tenere', 'sotto', 'osservazione.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Poiché', 'un', 'paziente', 'splenectomizzato', 'è', 'considerato', 'un', 'paziente', 'speciale,', 'deve', 'ricevere', 'un', 'trattamento', 'antibiotico', 'il', 'prima', 'possibile', 'anche', 'se', 'la', 'ferita', 'non', 'sembra', 'infetta.'], ['Dovete', 'assicurarvi', 'che', 'il', 'cane', 'sia', 'vostro', '(dovreste', 'chiedere', 'se', ""l'animale"", 'è', 'correttamente', 'vaccinato)', 'e', 'che', 'il', 'paziente', 'sia', 'correttamente', 'vaccinato', '(5', 'dosi', 'di', 'tetano,', 'non', 'sarebbe', 'necessario', 'il', 'tetano);', 'fare', 'una', 'notifica', 'di', 'Animal', 'Assault,', 'per', ""l'osservazione"", ""dell'animale"", 'e', 'prendere', 'provvedimenti', 'se', 'questo', 'è', 'necessario.']]","[['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +112_154,"[['QUESTION', 'TYPE:', 'GINECOLOGIA', 'E', 'OSTETRICIA'], ['CLINICAL', 'CASE:'], ['Paziente', 'di', '67', 'anni', 'con', 'anamnesi', 'di', 'menopausa', 'a', '55', 'anni,', '3', 'gravidanze', 'con', '3', 'parti', 'eutanasici,', 'diabete', 'di', 'tipo', '2', 'con', '6', 'anni', 'di', 'evoluzione,', 'trattamento', 'con', 'nifedipone', 'per', ""l'ipertensione.""], ['Consultazione', 'a', 'causa', 'di', 'una', 'metrorragia', 'intermittente', 'di', '2', 'mesi.'], [""L'esame"", 'ginecologico', 'ha', 'rivelato', 'genitali', 'esterni', 'senza', 'lesioni,', 'cervice', 'atrofica,', 'utero', 'e', 'annessi', 'normali', 'alla', 'palpazione', 'e', 'uno', 'studio', 'citologico', 'normale', 'della', 'cervice.'], [""L'ecografia"", 'transvaginale', 'ha', 'mostrato', 'un', 'endometrio', 'iperecogeno', 'di', '7', 'mm.'], ['Quale', 'dei', 'seguenti', 'esami', 'è', 'il', 'più', 'appropriato', 'e', 'il', 'più', 'sensibile', 'per', 'stabilire', 'una', 'diagnosi?'], ['1-', 'Conizzazione', 'della', 'cervice.'], ['2-', 'Citologia', 'endometriale.'], ['3-', 'Isteroscopia', 'e', 'biopsia', 'endometriale.'], ['4-', 'Risonanza', 'magnetica', 'del', 'bacino.'], ['5-', 'Esame', 'in', 'anestesia', 'del', 'tratto', 'genitale', 'e', 'biopsia', 'della', 'cervice', 'e', ""dell'endometrio.""], ['RISPOSTA', 'CORRETTA:', '3'], ['La', 'risposta', 'corretta', 'è', '3'], ['Lo', 'studio', 'che', 'ci', 'fornisce', 'il', 'maggior', 'numero', 'di', 'informazioni', 'sulla', 'patologia', 'endometriale', 'è', ""l'isteroscopia,"", 'che', 'ci', 'permette', 'di', 'eseguire', 'una', 'biopsia', 'endometriale', 'mirata.'], ['La', 'citologia', 'endometriale', 'viene', 'eseguita', 'in', 'cieco', 'e', 'presenta', 'un', 'elevato', 'numero', 'di', 'falsi', 'negativi.'], ['La', 'risonanza', 'magnetica', 'ci', 'aiuterà', 'a', 'stadiare', 'il', 'cancro', ""dell'endometrio.""]]","[['O', 'O', 'O', 'O', 'O'], ['O', 'O'], 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'del', 'recettore', 'sensibile', 'al', 'calcio.'], ['Si', 'tratta', 'di', 'una', 'domanda', 'difficile,', 'in', 'quanto', 'è', 'necessario', 'conoscere', 'i', 'dati', 'relativi', 'a', 'una', 'malattia', 'che', 'di', 'solito', 'non', 'viene', 'richiesta', 'nel', 'MIR.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'mesi,', 'con', 'perdita', 'di', 'appetito', 'e', 'di', 'peso', 'e', 'maggiore', 'difficoltà', 'a', 'concentrarsi', 'sugli', 'studi.'], [""L'anamnesi"", 'evidenzia', 'anche', 'che', 'ha', 'perso', 'interesse', 'a', 'uscire', 'con', 'gli', 'amici,', 'ha', 'idee', 'di', 'morte', 'senza', 'ideazioni', 'autolesionistiche', 'e', 'cognizioni', 'pessimistiche', 'sul', 'futuro.'], ['Il', 'loro', 'peso', 'è', 'pari', 'al', '90%', 'di', 'quello', 'considerato', 'ideale', 'per', 'età', 'e', 'sesso.'], ['Nessuna', 'fobia', 'del', 'peso', 'o', 'distorsione', ""dell'immagine"", 'corporea.'], ['La', 'diagnosi', 'più', 'appropriata', 'è:'], ['1-', 'Anoressia', 'nervosa.'], ['2-', 'Disturbo', ""d'ansia.""], ['3-', 'Disturbo', 'borderline', 'di', 'personalità.'], ['4-', 'Distimia.'], ['5-', 'Disturbo', 'depressivo', 'maggiore.'], ['RISPOSTA', 'CORRETTA:', '5'], ['Appena', 'sentiamo', 'la', 'parola', 'peso,', 'ci', 'orientiamo', 'verso', ""l'anoressia"", 'nervosa,', 'ma', ""l'anoressia"", 'nervosa', 'ha', 'tre', 'caratteristiche:', 'una', 'significativa', 'perdita', 'di', 'peso', 'autoindotta,', 'una', 'distorsione', ""dell'immagine"", 'corporea', 'e', ""l'amenorrea.""], ['Quindi', 'ne', 'rimuoviamo', '1'], ['Si', 'perde', 'peso', 'quando', 'si', 'è', 'tristi,', 'si', 'è', 'preoccupati,', 'ecc...', 'Il', '3', 'non', 'ha', 'senso', 'nella', 'MIR', 'a', 'causa', 'della', 'clinica', '-', 'nella', 'realtà', 'la', 'storia', 'è', 'diversa', 'e', 'in', 'psichiatria', 'tutto', 'è', 'evoluzione', '-.'], ['4', 'deve', 'soddisfare', 'criteri', 'temporali', 'che', 'qui', 'non', 'sono', 'soddisfatti.'], ['Quindi', 'siamo', 'tra', 'i', '2', 'e', 'i', '5'], ['Depressione', 'o', 'ansia?'], ['Non', 'ci', 'sono', 'segni', 'clinici', 'di', 'ansia', 'e', 'soddisfa', 'anche', 'i', 'criteri', 'per', 'la', 'depressione.'], ['Alla', 'povera', 'ragazza', 'è', 'stata', 'diagnosticata', 'la', 'depressione.'], ['La', 'risposta', 'è', '5', ""(un'altra"", 'possibilità', 'è', 'che', 'stesse', 'studiando', 'il', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +530_167,"[['QUESTION', 'TYPE:', 'NEFROLOGIA'], ['CLINICAL', 'CASE:'], ['Un', 'paziente', 'con', 'nota', 'malattia', 'renale', 'cronica', 'avanzata', '(CKD', 'G4,', 'eGFR', '20', 'ml/min),', 'che', 'arriva', 'al', 'pronto', 'soccorso', 'per', 'debolezza', 'generale', 'e', 'viene', 'trovato', 'con', 'una', 'grave', 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'salino', 'con', 'insulina,', 'salbutamolo,', 'furosemide,', 'e', 'valutando', 'la', 'dialisi', 'se', 'non', ""c'è"", 'una', 'buona', 'risposta).']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +494_157,"[['QUESTION', 'TYPE:', 'EMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '26', 'anni', 'ha', 'consultato', 'per', 'una', 'sensazione', 'di', 'debolezza', 'generalizzata', 'che', 'si', 'è', 'sviluppata', 'progressivamente', 'nel', 'corso', 'di', 'tre', 'settimane,', 'diventando', 'particolarmente', 'intensa', 'negli', 'ultimi', 'due', 'giorni.'], ['Da', 'un', 'paio', ""d'anni"", 'riferisce', 'episodi', 'di', 'dolore', 'articolare', 'alle', 'mani', 'che', 'hanno', 'richiesto', ""l'uso"", 'di', 'farmaci', 'antinfiammatori,', 'nonché', 'la', 'comparsa', 'di', 'alcune', 'lesioni', 'eritematose', 'di', 'causa', 'non', 'chiara', 'nella', 'zona', 'del', 'décolleté,', 'soprattutto', 'in', 'estate.'], [""L'esame"", 'fisico', 'ha', 'rivelato', 'solo', 'un', 'pallore', 'della', 'pelle', 'e', 'delle', 'mucose', 'e', 'una', 'frequenza', 'cardiaca', 'di', '100', 'bpm.'], [""L'emogramma"", 'evidenzia:', 'Hb', '6', 'gr/dL,', 'Hto', '27', '%,', 'MCV', '105', 'fL,', '3.42', 'leucociti/mm3', '(2300', 'neutrofili/mm3,', '800', 'linfociti/mm3,', '250', 'monociti/mm3,', '50', 'eosinofili/mm3,', '20', 'basofili/mm3),', 'piastrine', '170.000/mm3.'], ['Biochimica:', 'AST', '30', 'UI/L,', 'ALT', '35', 'UI/L,', 'GGT', '59', 'UI/L,', 'fosfatasi', 'alcalina', '105', 'UI/L,', 'LDH', '490', 'UI/L,', 'urea', '20', 'mg/dL,', 'creatinina', '0,8', 'mg/dL.'], ['Sulla', 'base', 'delle', 'informazioni', 'disponibili,', 'si', 'prega', 'di', 'indicare', 'quali', 'dei', 'seguenti', 'parametri', 'analitici', 'aggiuntivi', 'sarebbe', 'necessario', 'conoscere', 'per', 'prendere', 'la', 'decisione', 'immediata', 'più', 'appropriata:'], ['1-', 'Vitamina', 'B12.'], ['2-', 'Anticorpi', 'antinucleari.'], ['3-', 'Test', 'di', 'Coombs', 'diretto.'], ['4-', 'Anticorpi', 'anti-DNA.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Discutono', 'il', 'caso', 'di', 'una', 'giovane', 'donna', 'con', 'sintomi', 'di', 'una', 'malattia', 'sistemica', 'di', 'probabile', 'origine', 'autoimmune', '(lupus)', 'che', 'presenta', 'anemia', 'macrocitica;', 'le', 'opzioni', '2', 'e', '4', 'sono', 'opzioni', 'per', 'identificare', 'la', 'malattia', 'autoimmune,', 'ma', 'quello', 'che', 'ci', 'chiedono', 'è', 'cosa', 'fare', 'per', 'trattare', ""l'anemia,"", 'quindi', 'dovremmo', 'sospettare', 'che', ""l'anemia"", 'sia', 'secondaria', 'alla', 'malattia', 'autoimmune', 'e', 'quindi', 'richiedere', 'un', 'test', 'di', 'Coombs', 'diretto,', 'poiché', 'se', 'è', 'positivo', 'il', 'paziente', 'non', 'sarà', 'trasfuso,', 'a', 'meno', 'che', 'non', 'sia', 'estremamente', 'grave,', 'e', 'la', 'causa', 'primaria', 'dovrebbe', 'essere', 'trattata.'], ['Si', 'parla', 'anche', 'di', 'insorgenza', 'rapida,', 'che', 'nel', 'caso', 'della', 'vitamina', 'B12', 'è', 'più', 'progressiva.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +117_112,"[['QUESTION', 'TYPE:', 'INFETTOLOGIA'], ['CLINICAL', 'CASE:'], ['Un', 'uomo', 'di', '64', 'anni', 'si', 'consulta', 'per', 'febbre,', 'tosse,', 'dispnea', 'e', 'dolore', 'pleuritico', 'destro', 'di', '1', 'settimana.'], ['La', 'radiografia', 'del', 'torace', 'mostra', 'un', 'versamento', 'pleurico', 'destro', 'localizzato', 'che', 'occupa', 'due', 'terzi', ""dell'emitorace.""], ['Durante', 'la', 'toracentesi,', 'è', 'stato', 'estratto', 'un', 'fluido', 'giallastro', 'e', ""l'analisi"", 'ha', 'mostrato:', 'leucociti', '15.000/uL,', '92%', 'neutrofili,', 'glucosio', '30', 'mg/dl,', 'pH', '7,', 'lattato', 'deidrogenasi', '3500', 'U/L,', 'adenosina', 'deaminasi', '45', 'U/L', 'e', 'assenza', 'di', 'germi', 'nella', 'colorazione', 'GRAM.'], ['Qual', 'è', 'la', 'prossima', 'azione', 'più', 'appropriata', 'per', 'questo', 'paziente?'], ['1-', 'Terapia', 'antibiotica', 'per', 'via', 'endovenosa.'], ['2-', 'Terapia', 'antibiotica', 'per', 'via', 'endovenosa', 'e', 'ripetizione', 'della', 'toracentesi', 'diagnostica', 'entro', '24', 'ore.'], ['3-', 'Terapia', 'antibiotica', 'per', 'via', 'endovenosa', 'e', 'ripetizione', 'della', 'toracentesi', 'diagnostica', 'in', 'assenza', 'di', 'miglioramento', 'entro', '48', 'ore.'], ['4-', 'Terapia', 'antibiotica', 'per', 'via', 'endovenosa', 'e', 'toracentesi', 'evacuativa', '(terapeutica)', 'se', 'vengono', 'isolati', 'germi', 'nella', 'coltura', 'del', 'liquido', 'pleurico.'], ['5-', 'Terapia', 'antibiotica', 'endovenosa', 'e', 'posizionamento', 'di', 'un', 'tubo', 'toracico', 'o', 'di', 'un', 'catetere', 'per', 'drenare', 'tutto', 'il', 'liquido', 'pleurico.'], ['RISPOSTA', 'CORRETTA:', '5'], ['Anche', 'in', 'questa', 'domanda', 'non', 'dovrebbero', 'esserci', 'molti', 'dubbi', '(tra', ""l'altro,"", 'credo', 'che', 'sia', 'più', 'una', 'domanda', 'da', 'pneumologo', 'che', 'da', 'me,', 'ma', 'vabbè,', 'con', 'questa', 'febbre', 'il', 'mio', 'amico', 'Emilienko', 'si', 'è', 'smarrito),', 'visto', 'che', 'il', 'quadro', 'clinico', 'fa', 'pensare', 'a', 'un', 'versamento', 'pleurico', 'parapneumonico,', 'le', 'caratteristiche', 'macroscopiche', 'del', 'liquido', 'lo', 'sembrano', 'e', 'la', 'sua', 'analisi', 'mostra', 'che', 'il', 'versamento', 'è', 'anche', 'complicato,', 'quasi', 'sul', 'punto', 'di', 'essere', 'un', 'empiema', '(LDH', 'molto', 'alto,', 'cellularità', 'con', 'predominanza', 'di', 'PMN,', 'consumo', 'di', 'glucosio).'], ['A', 'quel', 'pH,', 'inoltre,', '(e', 'sapendo', 'che', 'il', 'versamento', 'è', 'già', 'localizzato)', 'il', 'tubo', 'endotoracico', 'è', 'più', 'che', 'indicato.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +27_203,"[['QUESTION', 'TYPE:', 'INFETTIVO'], ['CLINICAL', 'CASE:'], ['Un', 'paziente', 'di', '52', 'anni', 'viene', 'ricoverato', 'in', 'ospedale', 'con', 'una', 'grave', 'polmonite.'], ['Con', 'un', 'trattamento', 'antibiotico', 'appropriato,', 'i', 'sintomi', 'respiratori', 'migliorano.'], ['Dopo', '4', 'giorni', 'di', 'degenza,', 'la', 'sua', 'evoluzione', 'è', 'stata', 'complicata', 'dalla', 'comparsa', 'di', 'un', 'grave', 'processo', 'diarroico.'], ['Qual', 'è', 'il', 'microrganismo', 'più', 'frequentemente', 'responsabile', 'di', 'questa', 'condizione?'], ['1-', 'Salmonella', 'enterica.'], ['2-', 'Lo', 'stesso', 'batterio', 'che', 'causa', 'la', 'polmonite,', 'che', 'è', 'diventato', 'resistente', ""all'antibiotico.""], ['3-', 'Campylobacter', 'jejuni.'], ['4-', 'Clostridium', 'difficile.'], ['5-', 'Yersinia', 'enterocolitica.'], ['RISPOSTA', 'CORRETTA:', '4'], ['In', 'questo', 'caso,', 'visto', 'il', 'trattamento', 'antibiotico', 'somministrato', 'e', 'la', 'gravità', 'della', 'diarrea,', 'sembra', 'che', 'si', 'tratti', 'di', ""un'infezione"", 'da', 'Clostridium.'], [""L'opzione"", '2', 'è', 'poco', 'credibile,', 'infatti,', 'per', 'quanto', 'i', 'pazienti', 'con', 'CAP', 'possano', 'avere', 'diarrea', 'associata,', 'è', 'improbabile', 'che', 'un', 'batterio', 'sia', 'sensibile', 'a', 'un', 'antibiotico', ""all'inizio"", 'del', 'quadro', 'e', 'smetta', 'di', 'esserlo', 'dopo', '3', 'giorni.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise']]" +471_139,"[['QUESTION', 'TYPE:', 'CHIRURGIA', 'ORTOPEDICA', 'E', 'TRAUMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Bambino', 'di', '7', 'anni', 'portato', 'al', 'pronto', 'soccorso', 'dopo', 'essere', 'caduto', 'da', ""un'altalena"", 'sulla', 'mano', 'destra.'], ['Nessun', 'precedente', 'di', 'interesse.'], ['Presenta', 'una', 'deformità', 'a', 'forchetta', 'del', 'polso', 'e', 'impotenza', 'funzionale,', 'con', 'una', 'situazione', 'neurovascolare', 'distale', 'normale.'], ['Quale', 'lesione', 'si', 'aspetta', 'di', 'trovare', 'nella', 'radiografia', 'urgente', 'che', 'sta', 'richiedendo?'], ['1-', 'Frattura', 'di', 'Monteggia', '-', 'lussazione.'], ['2-', 'Frattura', 'della', 'testa', 'radiale.'], ['3-', 'Epifisiolisi', 'del', 'radio', 'distale.'], ['4-', 'Frattura', 'a', 'stelo', 'verde', ""dell'ulna.""], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Con', 'la', 'deformità', 'e', 'il', 'dolore', 'nel', 'radio', 'distale,', 'ci', 'aspettiamo', 'una', 'frattura', 'a', 'quel', 'livello,', 'quindi', 'segniamo', '3'], ['Tuttavia,', 'ritengo', 'che', 'sia', 'contestabile', 'in', 'quanto', 'potrebbe', 'anche', 'avere', 'una', 'concomitante', 'frattura', 'del', 'peduncolo', 'verde', 'ulnare,', 'anche', 'se', 'la', 'lesione', 'principale', 'è', 'al', 'radio.']]","[['O', 'O', 'O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +327_81,"[['QUESTION', 'TYPE:', 'ENDOCRINOLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '30', 'anni', 'si', 'presenta', 'in', 'ambulatorio', 'riferendo', 'ansia,', 'perdita', 'di', 'peso', 'di', 'circa', '6', 'kg', 'e', 'una', 'sensazione', 'di', 'nervosismo', 'negli', 'ultimi', 'tre', 'mesi.'], [""L'esame"", 'fisico', 'ha', 'rivelato', 'tachicardia,', 'iperreflessia', 'e', 'assenza', 'di', 'gozzo.'], ['I', 'valori', 'di', 'TSH', 'sono', '<', '0,01', 'microU/mL,', 'il', 'T4', 'è', 'elevato', 'e', 'i', 'livelli', 'di', 'tireoglobulina', 'sono', 'diminuiti.'], ['La', 'scintigrafia', 'rileva', ""un'assenza"", 'di', 'captazione', 'nella', 'regione', 'tiroidea.'], ['Quale', 'ritiene', 'sia', 'la', 'diagnosi', 'più', 'probabile?'], ['1-', 'Tireotossicosi', 'fittizia.'], ['2-', 'Ipertiroidismo', 'dovuto', 'alla', 'malattia', 'di', 'Graves.'], ['3-', 'Teratoma', 'ovarico', '(struma', 'ovarico).'], ['4-', 'Tiroidite', 'subacuta.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '1'], ['Risposta', 'errata', '2:', 'La', 'malattia', 'di', 'Graves', 'è', 'caratterizzata', 'da', 'ipertiroidismo', 'e', 'da', 'uno', 'o', 'più', 'dei', 'seguenti', 'fattori:', 'gozzo,', 'esoftalmo', 'e', 'mixedema', 'pretibiale.'], ['Risposta', 'errata', '4:', 'Il', 'sintomo', 'più', 'evidente', 'della', 'tiroidite', 'subacuta', 'è', 'il', 'dolore', 'al', 'collo.'], ['Talvolta', 'il', 'dolore', 'può', 'estendersi', 'alla', 'mascella', 'o', 'alle', 'orecchie.'], [""L'ingrossamento"", 'doloroso', 'della', 'tiroide', 'può', 'durare', 'settimane', 'o', 'mesi.'], ['E', 'di', 'solito', 'hanno', 'bassi', 'livelli', 'sierici', 'di', 'ormone', 'stimolante', 'la', 'tiroide', '(TSH).'], ['Elevato', 'livello', 'di', 'T4', 'libero', 'nel', 'siero.'], ['Elevato', 'livello', 'di', 'tireoglobulina', 'nel', 'siero.'], ['Risposta', 'errata', '4:', 'Tumore', 'molto', 'raro.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], 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'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +189_71,"[['QUESTION', 'TYPE:', 'PEDIATRIA'], ['CLINICAL', 'CASE:'], ['Bambino', 'di', '10', 'anni', 'con', 'brevi', 'episodi', 'di', 'distrazione', '(<', '1', 'minuto)', 'in', 'cui', 'non', 'risponde', 'ai', 'richiami', 'e', 'sbatte', 'le', 'palpebre.'], ['Un', 'EEG', 'mostra', 'scariche', 'di', 'onde', 'spike', 'a', '3', 'cicli', 'al', 'secondo.'], ['Il', 'trattamento', 'elettivo', 'di', 'prima', 'linea', 'sarebbe', 'con:'], ['1-', 'Valproato.'], ['2-', 'Carbamacepina.'], ['3-', 'Fenitoina.'], ['4-', 'Gabapentina.'], ['5-', 'Clonazepam.'], ['RISPOSTA', 'CORRETTA:', '1'], ['Le', 'crisi', 'descritte', 'e', ""l'EEG"", 'corrispondono', 'alle', 'tipiche', 'crisi', 'di', 'assenza', 'e', 'il', 'trattamento', 'iniziale', 'di', 'scelta', 'è', ""l'acido"", 'valproico.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +508_148,"[['QUESTION', 'TYPE:', 'DIGESTIVO'], ['CLINICAL', 'CASE:'], ['Donna', 'di', '72', 'anni', 'senza', 'precedenti', 'di', 'interesse.'], ['Dopo', 'una', 'colica', 'renale', 'complicata,', 'una', 'lesione', 'cistica', 'di', '2', 'cm', 'nella', 'coda', 'del', 'pancreas,', 'insieme', 'a', 'lesioni', 'cistiche', 'renali', 'multiple', 'bilaterali,', 'è', 'stata', 'riscontrata', 'casualmente', 'alla', 'TC', 'addominale.'], [""L'ecografia"", 'endoscopica', 'mostra', 'una', 'lesione', 'policistica', 'costituita', 'da', 'vescicole', 'multiple', 'con', 'calcificazione', 'centrale', 'nella', 'coda', 'del', 'pancreas,', 'senza', 'connessione', 'con', 'il', 'dotto', 'di', 'Wirsung.'], [""L'analisi"", 'del', 'liquido', 'è', 'compatibile', 'con', 'un', 'cistoadenoma', 'sieroso.'], ['Tra', 'i', 'seguenti,', 'qual', 'è', ""l'approccio"", 'più', 'corretto', 'per', 'la', 'gestione', 'di', 'questo', 'paziente?'], ['1-', 'Resezione', 'chirurgica', '(pancreatectomia', 'corporocaudale).'], ['2-', 'Puntura', 'endoscopica', 'guidata', 'da', 'ultrasuoni', 'ed', 'etanolizzazione', 'della', 'puntura.'], ['3-', 'Follow-up', 'della', 'lesione', 'mediante', 'risonanza', 'magnetica.'], ['4-', 'Trapianto', 'di', 'rene-pancreas.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Il', 'cistoadenoma', 'sieroso', 'del', 'pancreas', 'è', ""un'entità"", 'benigna,', 'spesso', 'policistica', '(chiamata', 'anche', 'adenoma', 'microcistico),', 'costituita', 'da', 'cellule', 'che', 'producono', 'collagene', '(non', 'mucinose).'], ['Di', 'solito', 'è', 'asintomatica', 'e', 'viene', 'scoperta', 'come', 'reperto', 'incidentale.'], ['Data', 'la', 'sua', 'natura', 'benigna,', ""l'intervento"", 'chirurgico', 'non', 'è', 'raccomandato', 'ed', 'è', 'riservato', 'solo', 'ai', 'pazienti', 'sintomatici', 'o', 'a', 'quelli', 'in', 'cui', 'la', 'natura', 'della', 'lesione', 'è', 'dubbia', 'dopo', 'uno', 'studio', 'completo', 'con', 'TC,', 'RM', 'ed', 'ecoendoscopia', 'con', 'biopsia.'], ['Spesso', 'è', 'sporadica,', 'ma', 'può', 'essere', 'associata', 'alla', 'sindrome', 'di', 'Von-Hippel-Lindau.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +151_70,"[['QUESTION', 'TYPE:', 'REUMATOLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'paziente', 'di', '25', 'anni', 'con', ""un'anamnesi"", 'di', 'rash', 'cutaneo', 'dopo', ""l'esposizione"", 'al', 'sole', 'e', 'occasionale', 'poliartrite', 'alle', 'articolazioni', 'delle', 'mani,', 'controllata', 'con', 'farmaci', 'antinfiammatori', 'non', 'steroidei,', 'ha', 'presentato', 'malessere', 'generale,', 'progressiva', 'sensazione', 'di', 'debolezza', 'generalizzata', 'e', 'pallore', 'negli', 'ultimi', '15', 'giorni.'], ['Le', 'analisi', 'del', 'sangue', 'hanno', 'mostrato', 'emoglobina', '7', 'g/dL,', 'MCV', '108', 'mm/h,', '150', 'piastrine/mm3,', '3000', 'leucociti/mm3,', 'LDH', 'elevato,', 'aptoglobina', 'non', 'rilevabile.'], ['Se', 'viene', 'scelto', 'un', 'solo', 'test', 'diagnostico,', 'indicare', 'quale', 'dei', 'seguenti', 'test', 'deve', 'essere', 'eseguito', 'per', 'primo:'], ['1-', 'Test', 'di', 'Coombs', 'diretto.'], ['2-', 'Anticorpi', 'antinucleari', '(ANA).'], ['3-', 'Vitamina', 'B12.'], ['4-', 'Ferritina.'], ['5-', 'Acido', 'folico.'], ['RISPOSTA', 'CORRETTA:', '1'], ['Il', 'quadro', 'clinico', 'e', 'biologico', 'di', 'questo', 'paziente', 'fa', 'sospettare', ""un'anemia"", 'emolitica', 'nel', 'contesto', 'del', 'lupus', 'eritematoso', 'sistemico.'], ['Se', 'si', 'deve', 'scegliere', 'un', 'solo', 'test', 'diagnostico,', 'e', 'questo', 'dovrebbe', 'essere', 'il', 'primo,', 'siamo', 'interessati', 'a', 'confermare', 'la', 'presenza', 'di', 'anemia', 'emolitica', 'autoimmune', 'con', 'il', 'test', 'di', 'Coombs', 'diretto', 'per', 'iniziare', 'il', 'trattamento.'], ['Il', 'resto', 'dei', 'test', 'può', 'aspettare...']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +404_139,"[['QUESTION', 'TYPE:', 'OFTALMOLOGIA', '(ECTOPICA)'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '70', 'anni', 'con', 'anamnesi', 'di', 'anoressia,', 'perdita', 'di', 'peso,', 'fastidio', 'alla', 'muscolatura', 'e', 'alle', 'articolazioni', 'prossimali', 'e', 'dolore', 'nella', 'regione', 'temporo-mandibolare', 'si', 'è', 'recata', 'al', 'pronto', 'soccorso', 'per', 'una', 'perdita', 'unilaterale', 'della', 'vista', '(movimento', 'della', 'mano),', 'di', 'insorgenza', 'improvvisa', 'e', 'indolore', '(difetto', 'pupillare', 'afferente).'], ['Quale', 'test', 'richiedereste', 'per', 'primo', 'a', 'scopo', 'diagnostico?'], ['1-', 'Puntura', 'lombare.'], ['2-', 'Proteina', 'C-reattiva.'], ['3-', 'Angiografia', 'a', 'risonanza', 'magnetica.'], ['4-', 'Ecografia', 'carotidea.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '2'], ['La', 'paziente', 'è', 'una', 'donna', 'con', 'una', 'perdita', 'improvvisa,', 'indolore', 'e', 'grave', '(riesce', 'a', 'vedere', 'solo', 'il', 'movimento', 'delle', 'mani)', 'della', 'vista', 'in', 'un', 'occhio.'], [""L'esame"", 'oculistico', 'non', 'fornisce', 'molte', 'informazioni,', 'ma', 'solo', 'la', 'presenza', 'di', 'un', 'difetto', 'pupillare', 'afferente.'], ['Per', 'diagnosticare', 'il', 'problema', 'dobbiamo', 'basarci', 'sui', 'sintomi', 'sistemici.'], ['La', 'paziente', 'è', 'una', 'donna', 'anziana', 'con', 'i', 'sintomi', 'tipici', 'della', 'polimialgia', 'reumatica,', 'e', 'il', 'dolore', 'nella', 'regione', 'temporo-mandibolare', 'è', 'molto', 'suggestivo.'], ['Si', 'tratta', 'di', 'arterite', 'a', 'cellule', 'giganti', 'o', 'arterite', 'temporale.'], ['La', 'manifestazione', 'oculare', 'più', 'comune', 'è', 'la', 'neuropatia', 'ottica', 'ischemica', 'anteriore.'], ['Nel', 'fundus', 'si', 'noterebbe', 'probabilmente', 'un', 'edema', 'papillare', 'di', ""quell'occhio,"", 'con', 'un', 'colore', 'bianco-gesso.'], ['Molto', 'caratteristico', 'di', 'queste', 'gravi', 'neuropatie', 'ottiche', 'ischemiche', 'è', 'il', 'difetto', 'pupillare', 'afferente.'], ['In', 'caso', 'di', 'sospetto', 'di', 'arterite', 'a', 'cellule', 'giganti,', 'tre', 'marcatori', 'analitici', 'sono', 'caratteristicamente', 'elevati:', 'CRP,', 'VES', 'e', 'conta', 'piastrinica.'], ['Chiederemo', 'innanzitutto', 'uno', 'di', 'questi', 'parametri', 'e', 'lo', 'tratteremo,', 'spesso', 'senza', 'attendere', 'la', 'conferma', 'della', 'biopsia.'], ['Pertanto,', ""l'opzione"", '2', 'è', 'quella', 'corretta.']]","[['O', 'O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +215_106,"[['QUESTION', 'TYPE:', 'NEFROLOGIA'], ['CLINICAL', 'CASE:'], ['Un', 'paziente', 'di', '68', 'anni', 'si', 'è', 'presentato', 'per', 'edema', 'e', 'astenia.'], ['Gli', 'esami', 'del', 'sangue', 'hanno', 'mostrato', 'una', 'creatinina', 'di', '5', 'mg/dl,', ""un'emoglobina"", 'di', '10', 'g/dl', 'e', 'una', 'marcata', 'ipogammaglobulinemia', 'nel', 'siero', 'a', 'scapito', 'di', 'IgG,', 'IgA', 'e', 'IgM.'], [""L'analisi"", 'delle', 'urine', 'rivela', 'la', 'presenza', 'di', 'catene', 'leggere', 'kappa.'], ['Qual', 'è', 'il', 'suo', 'sospetto', 'diagnostico?'], ['1-', 'Malattia', 'da', 'deposito', 'di', 'catene', 'leggere', 'Kappa.'], ['2-', 'Sindrome', 'nefrosica.'], ['3-', 'Amiloidosi.'], ['4-', 'Mieloma', 'IgA', 'con', 'proteinuria', 'di', 'Bence-Jones.'], ['5-', 'Mieloma', 'a', 'catena', 'leggera.'], ['RISPOSTA', 'CORRETTA:', '1'], ['Questa', 'domanda', 'è', 'di', 'tipo', 'misto', 'emato-nefro.'], ['È', 'complicato,', 'quindi', 'escludiamo', 'le', 'opzioni', 'una', 'per', 'una.'], [""L'opzione"", '2,', 'sindrome', 'nefrosica,', 'oltre', 'a', 'essere', 'ampia', 'e', 'aspecifica,', 'non', 'sarebbe', 'valutabile,', 'poiché', 'non', 'ci', 'viene', 'fornita', 'la', 'quantificazione', 'delle', 'proteine', 'nelle', 'urine', '(ci', 'viene', 'detto', 'solo', 'che', ""l'analisi"", 'delle', 'urine', 'rivela', 'la', 'presenza', 'di', 'catene', 'leggere', 'kappa,', 'non', 'la', 'quantità).'], [""L'opzione"", '3', 'sarebbe', 'improbabile;', ""nell'amiloidosi,"", 'le', 'catene', 'leggere', 'che', 'si', 'depositano', 'di', 'solito', 'sono', 'di', 'tipo', 'lambda.'], ['Anche', ""l'opzione"", '4', 'sembra', 'improbabile,', 'poiché', 'nel', 'mieloma', 'IgA', 'ci', 'si', 'aspetterebbe', 'un', 'picco', 'monoclonale', 'di', 'IgA,', 'che', 'in', 'questo', 'caso', 'non', 'compare.'], ['Il', 'dubbio', 'che', 'mi', 'sorge', 'è', 'tra', '1', 'e', '5;', 'opterei', 'per', ""l'1,"", 'perché', 'questa', 'entità', 'soddisfa', 'le', 'caratteristiche', 'descritte', '(assenza', 'di', 'picco', 'monoclonale', 'nella', 'maggior', 'parte', 'dei', 'casi,', 'insufficienza', 'renale', 'acuta', 'e', 'presenza', 'di', 'catene', 'kappa', 'nelle', 'urine),', 'essendo', 'il', 'mieloma', 'a', 'catene', 'leggere', ""un'entità"", 'un', ""po'"", 'più', 'ampia,', 'ma', ""l'opzione"", '5', 'potrebbe', 'comunque', 'essere', 'considerata', 'valida.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 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'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +264_135,"[['QUESTION', 'TYPE:', 'PNEUMOLOGIA'], ['CLINICAL', 'CASE:'], ['Una', 'donna', 'di', '24', 'anni', 'viene', 'trovata', 'distesa', 'in', 'strada', 'dai', 'passanti.'], [""All'arrivo"", ""dell'équipe"", 'di', 'emergenza', 'è', 'stata', 'trovata', 'con', 'una', 'saturazione', 'di', 'ossigeno', ""dell'88%"", 'respirando', 'aria', 'ambiente', 'e,', ""all'esame,"", 'con', 'le', 'pupille', 'a', 'punta.'], ['È', 'stata', 'trasferita', 'al', 'pronto', 'soccorso', ""dell'ospedale"", 'più', 'vicino,', 'dove', ""l'emogasanalisi"", 'arteriosa', 'al', 'basale', 'ha', 'mostrato:', 'pH', '7,25,', 'PaC02', '60', 'mmHg,', 'Pa02', '58', 'mmHg,', 'bicarbonato', '26', 'mEq/1', 'ed', 'eccesso', 'di', 'basi', 'di', '-1'], ['Il', 'sodio', 'nel', 'sangue', 'è', 'pari', 'a', '137', 'mEq/1', 'e', 'il', 'cloruro', 'a', '100', 'mEq/1:'], ['1-', 'Insufficienza', 'respiratoria', 'parziale.'], ['2-', 'Acidosi', 'metabolica.'], ['3-', 'Acidosi', 'respiratoria', 'pura.'], ['4-', 'Alcalosi', 'respiratoria', 'dovuta', 'alla', 'mancanza', 'di', 'cloro.'], ['5-', 'I', 'gas', 'ematici', 'possono', 'essere', 'prelevati', 'solo', 'dal', 'sangue', 'venoso.'], ['RISPOSTA', 'CORRETTA:', '3'], [""L'acidosi"", 'con', 'PCO2', 'elevata,', 'ipossiemia', 'e', 'bicarbonato', 'normale', 'suggerisce', ""un'acidosi"", 'respiratoria', 'acuta', 'di', 'rapida', 'insorgenza', 'probabilmente', 'dovuta', 'a', 'intossicazione', 'da', 'farmaci.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim'], ['O', 'O', 'O'], ['B-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim', 'I-Claim']]" +594_80,"[['QUESTION', 'TYPE:', 'PEDIATRIA'], ['CLINICAL', 'CASE:'], ['Un', 'neonato', 'di', '2', 'mesi', 'con', 'un', 'raffreddore', 'delle', 'vie', 'respiratorie', 'superiori', 'della', 'durata', 'di', '3', 'giorni,', 'inizia', 'con', 'una', 'moderata', 'distress', 'respiratoria', 'e', ""un'auscultazione"", 'polmonare', 'con', 'sibili', 'espiratori.'], ['La', 'saturazione', 'di', 'ossigeno', 'è', ""dell'89%.""], ['Il', 'virus', 'respiratorio', 'sinciziale', 'viene', 'isolato', ""nell'essudato"", 'nasofaringeo.'], ['Quale', 'dei', 'seguenti', 'trattamenti', 'ritiene', 'più', 'appropriato', 'per', 'questa', 'condizione?'], ['1-', 'Rivabirina', 'orale.'], ['2-', 'Salbutamolo', 'nebulizzato.'], ['3-', 'Ossigeno', 'supplementare.'], ['4-', 'Corticosteroidi', 'per', 'via', 'endovenosa.'], ['5-', 'nan'], ['RISPOSTA', 'CORRETTA:', '3'], ['Viene', 'presentato', 'un', 'caso', 'di', 'bronchiolite', 'positiva', ""all'RSV.""], ['Secondo', 'le', 'attuali', 'raccomandazioni,', 'è', 'necessario', 'iniziare', ""l'ossigenoterapia"", 'supplementare.']]","[['O', 'O', 'O'], ['O', 'O'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['B-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise', 'I-Premise'], ['O', 'O', 'O', 'O', 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