Euskara:
| Funtzioak                                                                               | Entzimak                                                                                                                                                                                                                                             |
|-----------------------------------------------------------------------------------------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| Gantz-azidoen β-oxidaziorako                                                            | Kate luze eta oso luzeko azil-CoA sintetasak<br>Azil-CoA oxidasa<br>Proteina multifuntzionala<br>3-zetoazil-CoA tiolasa<br>Δ³,Δ²-enoil-CoA isomerasa<br>2,4-dienoil-CoA erreduktasa<br>D-3-hidroxiazil-CoA deshidratasa<br>Karnitin aziltransferasak |
| Glizerolipidoen edo<br>plasmalogenoen sintesirako                                       | Dihidroxiazetona fosfato aziltransferasa<br>Azil-CoA erreduktasa<br>Alkildihidroxiazetona fosfato sintetasa<br>Azil/alkil dihidroxiazetona fosfato erreduktasa                                                                                       |
| Kolesterolaren eta dolikolaren sintesirako                                              | 3-hidroxi-3-metilglutaril-CoA erreduktasa<br>Mebalonato kinasa<br>Dihidroxilanosterol oxidasa<br>Esteroide 14-erreduktasa<br>Esteroide 8-erreduktasa<br>Esteroide 3-keto erreduktasa<br>SCP-2 (Sterol Carrier Protein-2)                             |
| Azido biliarren sintesirako                                                             | Kolesterol 7α-hidroxilasa<br>Azil-CoA biliarra:aminoazido-N-aziltransferasa                                                                                                                                                                          |
| Purinen katabolismorako                                                                 | Xantina oxidasa<br>Urato oxidasa<br>Alantoinasa<br>Alantoikasa                                                                                                                                                                                       |
| Oxigenoaren metabolismorako<br>eta oxigenoaren espezie<br>erreaktiboak desagerrarazteko | Katalasa Cu, Zn-superoxido dismutasa Glutation peroxidasa Epoxido hidrolasa                                                                                                                                                                          |
| Glioxilatoaren eta aminoazidoen metabolismorako                                         | Alanina—glioxilato aminotransferasa L-α-hidroxiazido oxidasa (A eta B motak) D-aminoazido oxidasa D-aspartato oxidasa L-pipekolato oxidasa Glutaril-CoA oxidasa                                                                                      |
| Bestelakoak                                                                             | Azetil-CoA hidroxilasa Azil-CoA hidroxilasa 2-enoil-CoA erreduktasa Poliamina oxidasa ATPasa P-glikoproteinarekin erlazionatutako ATP lotzen duen proteina GTP-rekin lotzen den proteina txikia                                                      |

![](_page_3_Figure_1.jpeg)

**1. irudia.** Animalia ezberdinen purinen degradazioaren bidean peroxisomek betetzen dituzten funtzioak.

Español:
| Funciones| Enzimas|
|----------|----------|
| Para la β-oxidación de ácidos grasos| azil-CoA sintetasas de cadena larga y muy larga  <br>Azil-CoA oxidasa<br>Proteína multifuncional<br>3-cetoacil-CoA tiolasa<br>Δ³,Δ²-enoil-CoA isomerasa<br>2,4-dienoil-CoA reductasa<br>D-3-hidroxiacil-CoA deshidratasa<br>Carnitina aciltransferasas|
| Para la síntesis de glicerolípidos o <br>plasmalógenos| Dihidroxiacetona fosfato aciltransferasa<br>Acil-CoA reductasa<br>Alquildihidroxiacetona fosfato sintetasa<br>Acil/alquil dihidroxiacetona fosfato reductasa|
| Para la síntesis de colesterol y dolicol| 3-hidroxi-3-metilglutaril-CoA reductasa<br>Mebalonato quinasa<br>Dihidroxilanosterol oxidasa<br>Esteroide 14-reductasa<br>Esteroide 8-reductasa<br>Esteroide 3-ceto reductasa<br>SCP-2 (Sterol Carrier Protein-2)|
| Para la síntesis de ácidos biliares| Colesterol 7α-hidroxilasa<br>Acil-CoA biliar:aminoácido-N-aciltransferasa|
| Para el catabolismo de purinas| Xantina oxidasa<br>Urato oxidasa<br>Alantoinasa<br>Alantoicasa|
| Para el metabolismo del oxígeno<br> para eliminar las especies<br> reactivas del oxígeno| Catalasa Cu, Zn-superóxido dismutasa Glutation peroxidasa Epóxido hidrolasa|
| Para el metabolismo del glioxilato y de los aminoácidos| Alanina—glioxilato aminotransferasa L-α-hidroxiácido oxidasa (tipos A y B) D-aminoácido oxidasa D-aspartato oxidasa L-pipecolato oxidasa Glutaril-CoA oxidasa|
| Otros| Acetil-CoA hidroxilasa Acil-CoA hidroxilasa 2-enoil-CoA reductasa Poliamina oxidasa ATPasa Pequeña proteína que une el ATP relacionado con la P-glicoproteína Pequeña proteína que se une al GTP|

![](_page_3_Figure_1.jpeg)

**Imagen nº 1.** Funciones que cumplen los peroxisomas en la degradación de las purinas de diferentes animales.

English:
| Functions| Enzymes|
|----------|----------|
| For the β-oxidation of fatty acids| Long- and very long-chain acyl-CoA synthetases<br>Acyl-CoA oxidase<br>Multifunctional protein<br>3-ketoacyl-CoA thiolase<br>Δ³,Δ²-Enoyl-CoA isomerase<br>2,4-dienoyl-CoA reductase<br>D-3-hydroxyacyl-CoA dehydratase<br>Carnitine acyltransferases|
| For the synthesis of glycerolipids or<br>plasmalogens| Dihydroxyacetone phosphate acyltransferase<br>Acyl-CoA reductase<br>Alkyldihydroxyacetone phosphate synthetase<br>Acyl/alkyl dihydroxyacetone-phosphate reductase|
| For the synthesis of cholesterol and dolichol| 3-hydroxy-3-methylglutaryl-CoA reductase<br>Mebalonate kinase<br>Dihydroxylanosterol oxidase<br>Steroid 14-reductase<br>Steroid 8-reductase<br>Steroid 3-keto reductase<br>SCP-2 (Sterol Carrier Protein-2)|
| For the synthesis of bile acid| Cholesterol 7α-hydroxylase<br>Bile acyl-CoA: amino acid-N-acyltransferase|
| For purine catabolism| Xanthine oxidase<br>Urate oxidase<br>Allantoinase<br>Allantoinase|
| For the oxygen metabolism<br>and the scavenging of reactive<br>oxygen species| Catalase Cu, Zn-superoxide dismutase Glutathione peroxidase Epoxide hydrolase|
| For the glyoxylate and amino acid metabolism| Alanine-glyoxylate aminotransferase L-α-hydroxyacid oxidase (types A and B) D-amino acid oxidase D-aspartate oxidase L-pipecolate oxidase Glutaril-CoA oxidase|
| Others| Acetyl-CoA hydroxylase Acyl-CoA hydroxylase 2-Enoyl-CoA reductase Polyamine oxidase ATPase P-glycoprotein-linked ATP-binding protein Small GTP-binding protein|

![](_page_3_Figure_1.jpeg)

**Figure 1.** Functions performed by peroxisomes in the purine degradation pathway of different animals.