Hengzongshu/ArticleAgent huggingface dataset:
The COVID-19 outburst has brought serious demographical, economic, and social impacts. Moreover, in large countries, these consequences can vary from region to region. Therefore, authorities and experts lack the models to predict these various impacts at the regional level.

This paper presents deep neural network models to do a mid-term forecast of the COVID-19 effect in the Russian regions. The models are based on the various recurrent and sliding-window architectures and utilize the attention mechanism to consider the indicators of the neighbor regions. These models are trained on various data, including daily cases and deaths, the diseased age structure, transport availability of the regions, and the unemployment rate.

The experimental evaluation of the models shows that the demographic and healthcare indicators can significantly improve mid-term economic impact prediction accuracy. We also revealed that the neighboring regions' data helps predict the pandemic's healthcare and demographical impact. Namely, we have detected improvement for both the number of infected and the death rate.
We study experimentally the effect of linear plasma density gradients on the self-modulation of a 400 GeV proton bunch.

Results show that a positive/negative gradient in/decreases the number of micro-bunches and the relative charge per micro-bunch observed after 10 m of plasma. The measured modulation frequency also in/decreases. With the largest positive gradient we observe two frequencies in the modulation power spectrum.

Results are consistent with changes in wakefields' phase velocity due to plasma density gradient adding to the slow wakefields' phase velocity during self-modulation growth predicted by linear theory.
Fully nonlinear problem on unsteady water waves generated by impulsively moving obstacle is studied analytically.

Our method involves the reduction of Euler equations to the integral-differential system for the wave elevation together with normal and tangential fluid velocities at the free surface. Exact model equations are derived in explicit form in the case when the isolated obstacle is presented by totally submerged elliptic cylinder. Small-time asymptotic solution is constructed for the cylinder which starts with constant acceleration from rest.

It is demonstrated that the leading-order solution terms describe several wave regimes such as the formation of non-stationary splash jets by vertical rising or vertical submersion of the obstacle, as well as the generation of diverging waves is observed.
The thermoelectric response of 80-nm-thick strained HgTe films of a three-dimensional topological insulator (3D TI) has been studied experimentally. An ambipolar thermopower is observed where the Fermi energy moves from conducting to the valence bulk band. The comparison between theory and experiment shows that the thermopower is mostly due to the phonon drag contribution. In the region where the 2D Dirac electrons coexist with bulk hole states, the Seebeck coefficient is modified due to 2D electron - 3D hole scattering.
The Wiener index is a topological index of a molecular graph, defined as the sum of distances between all pairs of its vertices. Benzenoid graphs include molecular graphs of polycyclic aromatic hydrocarbons.

An edge thorny graph G is constructed from a catacondensed benzenoid graph H by attaching new graphs to edges of a perfect matching of H. A formula for the Wiener index of G is derived.

The index of the resulting graph does not contain distance characteristics of elements of H and depends on the Wiener index of H and distance properties of the attached graphs.
Bismuth-doped fibre amplifiers offer an attractive solution for expanding the bandwidth of fibre-optic telecommunication systems beyond the current C-band (1530-1565 nm). We report a bismuth-doped fibre amplifier in the spectral range from 1370 to 1490 nm, with a maximum gain exceeding 31 dB, and a noise figure as low as 4.75 dB. The developed system is studied for forward, backward, and bi-directional pumping schemes and three different signal power levels. The forward pumping scheme demonstrates the best performance in terms of the achieved noise figure. The developed amplifier can be potentially used as an in-line amplifier with >20dB gain in the spectral band from 1405 to 1460 nm.
We give a classification of $5$- and $6$-dimensional complex one-generated nilpotent bicommutative algebras
The studies on CpG islands (CGI) and Alu elements functions, evolution, and distribution in the genome started since the discovery in nineteen eighties (1981, 1986, correspondingly). Their highly skewed genome wide distribution implies the non-random retrotransposition pattern. Besides CGIs in gene promoters, CGIs clusters were observed in the homeobox gene regions and in the macrosatellites, but the whole picture of their distribution specifics was not grasped. Attempts to identify any causative features upon their (genome wide) distribution, such as the DNA context mediated preferred insertion sites of Alu repeats, have been made to ascribe their clusters location.

Recent emergence of high resolution 3D map of human genome allowed segregating the genome into the large scale chromatin domains of naturally observable nuclear subcompartments, or Topologically Associated Domains (TADs), designated by spatial chromatin distribution. We utilized the chromatin map to elucidate relations between large scale chromatin state and CpG rich elements landscape. In the course of analysis it was confirmed that genes, Alu and CGI clusters maintain obvious, albeit different in strength, preference for open chromatin.

For the first time it was clearly shown that the clusters density of the Alu and CGIs monotonically depend on the chromatin accessibility rate. In particular, the highest density of these elements is found in A1 euchromatin regions characterized by a high density of small length genes replicating in the early S-phase. It implies that these elements mediate (CGIs) or are a side element (Alus) of chromatin accessibility. We elucidated that both methylated and non-methylated CGIs display the affinity to chromatin accessibility. As a part of comparative genomics section, we elucidated that the dog's genome non-canonical structure, outstanding in mammals for its high CGIs abundance compared to gene number, is explained by the presence of dense tandem CGI extended hotspots (500 kb on average) in subtelomeric and pericentromeric regions with highly skewed CG content, and not by CGIs global distribution pattern shift. The study underlines the close association of CG-rich elements distribution with the newly introduced large scale chromatin state map, proposing a refined standpoint on interrelation of aforementioned genome elements and the chromatin state.
The program RECON has been designed for constructing profiles of nucleosome potential, characterizing the probability of nucleosome formation along DNA sequences.

The program used for recognition of nucleosome formation sites in genomic DNA sequences. It was developed using discriminant analysis based on a genetic algorithm method utilizing statistics for dinucleotide location within local regions of nucleosome formation sites.

The program RECON is available at http://wwwmgs.bionet.nsc.ru/mgs/programs/recon/.
We present a new class of spatiotemporal walk-off solitons in graded-index multimode optical fibers, characterized by unique properties. Their energies and pulsewidths depend only on chromatic and modal dispersion of the fiber, and on the input laser beam coupling conditions. Whereas the soliton properties are independent of the input pulse duration. The generated multimode solitons are composed by non-degenerate modes. However, upon propagation over distances comprising several hundreds of meters, the multimode solitons naturally evolve into singlemode pulses. For this reason, walk-off solitons are metastable objects, which are irreversibly attracted by the fundamental mode of the fiber.
We present a measurement of the time-dependent $CP$ violation parameters in $B^0\to\eta'K^0$ decays. The measurement is based on the full data sample containing $772\times 10^6$ $B\bar{B}$ pairs collected at the $\Upsilon(4S)$ resonance using the Belle detector at the KEKB asymmetric-energy $e^+e^-$ collider. The measured values of the mixing-induced and direct $CP$ violation parameters are: \begin{align} \sin 2 \phi^{\rm eff}_1 &= +0.68\pm 0.07 \pm 0.03, \nonumber \\ \mathcal{A}_{\eta'K^0} &= +0.03\pm 0.05\pm 0.04, \nonumber \end{align} where the first uncertainty is statistical and the second is systematic. The values obtained are the most accurate to date. Furthermore, these results are consistent with our previous measurements and with the world-average value of $\sin 2\phi_1$ measured in $B^0\to J/\psi K^0$ decays.}
Since December 2010 the CMD-3 and SND detectors detectors collect data at the VEPP-2000 electron-positron collider. In 2013-2015 the injection facility of the collider has undergone an upgrade of the injection system. The new BINP injection complex has been connected to the VEPP-2000 collider, so the restrictions connected to the lack of positrons and limited beam energy transfer do not apply any more. The collider luminosity in whole energy range is restricted now only by beam-beam effects.

VEPP-2000 collider started to collect data with two detectors at 2016 year. The collected data sample since 2010 corresponds more than 100 pb -1 of integrated luminosity per detector in the c.m. energy between 0.32 and 2GeV.

We will report here results of analysis of various hadronic cross sections from detectors both published and preliminary. These measurements are important by themselves and also because of the implications for anomaly of the magnetic moment of a muon (g-2) discrepancy.
An isoquinoline alkaloid berberine and its derivatives exhibit a wide range of biological activities including antibacterial, hypolipidemic, anticancer and other properties.

We synthesised and analysed a few different types of berberine derivatives and studied their inhibitory activity.

We have shown for the first time that berberine derivatives are effective inhibitors of the human DNA repair enzyme tyrosyl-DNA phosphodiesterase (Tdp1), which opens the possibility to use them as an adjuvant component of chemotherapy. Berberine-based sulfonates and sultones have been shown to exhibit high inhibitory activity against Tdp1.
At present great attention is paid to studying genetic regulation of farm animal adaptations to environmental conditions. This problem is very important due to a wide expansion of highly productive cattle breeds created in Europe and North America. However, until the present no investigation of changing semen quality in bulls of imported breeds during their adaptations to environmental conditions of Western Siberia has been conducted.

The aim of this study was to investigate semen quality peculiarities and the diversity of morphological sperm abnormalities in bulls of imported and local breeds kept in the environmental conditions of the southern part of Western Siberia. We determined sperm concentration, sperm count, and rate of sperm with progressive motility and percentage of morphologically normal spermatozoa. The rate of sperm abnormalities according to Blome's classification was determined too.

It was found that the mean values of sperm concentration, sperm motility and percentage of morphologically normal spermatozoa in the bulls investigated were similar to those in bulls kept in European countries. Inter-breed differences in these parameters were not found. However, bulls of the Red Danish, Angler, and Simmental breeds had a higher percentage of misshapen sperm head and pyriform sperm head than bulls of the Black-White breed. An inter-strain difference in sperm motility in bulls of the Black-White breed was observed. It was found that bulls of Reflection Sovereign 198998 strain had lover sperm motility than bulls of Wis Burke Ideal 1013415 strain. No inter-strain differences in sperm production, percentage of morphologically normal spermatozoa and rate of main sperm abnormalities were found. Thus, it has been found that the environmental conditions of the southern part of Western Siberia do not seriously affect the sperm production, sperm motility or percentage of morphologically normal spermatozoa in bulls. However, the increased rate of misshapen and pyriform sperm heads in the bulls of the foreign breeds points to a need to study sperm DNA fragmentation.
Using the density functional theory with the hybrid functional B3LYP and the basis of localized orbitals of the CRYSTAL17 program code, the dependences of the wavenumbers of normal long-wave ν vibrations on the P(GPa) pressure ν(cm−1) = ν0 + (dv/dP)·P + (d2v/dP2)·P and structural parameters R(Å) (R: a, b, c, RM-O, RC-O): ν(cm−1) = ν0 + (dv/dR) − (R − R0) were calculated. Calculations were made for crystals with the structure of calcite (MgCO3, ZnCO3, CdCO3), dolomite (CaMg(CO3)2, CdMg(CO3)2, CaZn(CO3)2) and aragonite (SrCO3, BaCO3, PbCO3). A comparison with the experimental data showed that the derivatives can be used to determine the P pressures, a, b, c lattice constants and the RM-O metal-oxygen, and the RC-O carbon-oxygen interatomic distances from the known Δν shifts. It was found that, with the increasing pressure, the lattice constants and distances R decrease, and the wavenumbers increase with velocities the more, the higher the ν0 is. The exceptions were individual low-frequency lattice modes and out-of-plane vibrations of the v2-type carbonate ion, for which the dependences are either nonlinear or have negative dv/dP (positive dv/dR) derivatives. The reason for this lies in the properties of chemical bonding and the nature of atomic displacements during these vibrations, which cause a decrease in RM-O and an increase in RC-O.
We describe a general N-solitonic solution of the focusing NLSE in the presence of a condensate by using the dressing method. We find a broad class of superregular solitonic solutions which are small perturbations at certain a moment of time. They describe the nonlinear stage of the modulation instability of the condensate and play an important role in the theory of freak waves.
Proton-driven plasma wakefield acceleration has been demonstrated in simulations to be capable of accelerating particles to the energy frontier in a single stage, but its potential is hindered by the fact that currently available proton bunches are orders of magnitude longer than the plasma wavelength. Fortunately, proton micro-bunching allows driving plasma waves resonantly.

In this paper, we propose using a hollow plasma channel for multiple proton bunch driven plasma wakefield acceleration and demonstrate that it enables the operation in the nonlinear regime and resonant excitation of strong plasma waves.

This new regime also involves beneficial features of hollow channels for the accelerated beam (such as emittance preservation and uniform accelerating field) and long buckets of stable deceleration for the drive beam. The regime is attained at a proper ratio among plasma skin depth, driver radius, hollow channel radius, and micro-bunch period.
The Bystrinsky Cu-Au-Fe porphyry-skarn and Shakhtama Mo ± Cu porphyry deposits in Eastern Transbaikalia, Russia, are spatially associated with a series of fertile and non-fertile calc-alkaline to shoshonitic I-type granitoid suites, ranging in composition from porphyritic monzonites and granodiorites to granodiorite- and granite-porphyries. The obtained zircon U-Pb geochronological data reveal a narrow age interval of 1–3 Ma for the igneous suites within the Bystrinsky deposit (ca. 159–163 Ma), which is consistent with the short-magmatic activity at the Shakhtama deposit (ca. 164–161 Ma). Within both deposits, the fertile magmatic pulses comprise hybrid, high-silica and high- to moderate-magnesian, oxidized melts with relatively high magmatic water contents. These weakly fractionated melts represent the late-stage magmatic pulses of the Shakhtama Complex. By contrast, the barren magmatic pulses comprise a wide range of compositions, generally with lower magmatic water contents and oxidation states as well as significant plagioclase fractionation and crustal contamination. The Shakhtama Mo-related porphyries are more evolved when compared to the Bystrinsky Cu-Au intrusions reflecting significant crustal assimilation in addition to amphibole-plagioclase fractionation. Both whole-rock geochemistry and zircon mineral chemistry from the Bystrinsky and Shakhtama deposits may be used as fertility indicators in target generation and regional mineral exploration in Eastern Transbaikalia. More specifically, we propose critical thresholds of whole-rock Sr/Y and 10,000*(Eu/Eu*)/Y ratios of > 65 and > 850, respectively, and zircon mineral Eu/Eu*, Ce/Ce* and Yb/Dy ratios of > 0.4, >750 and > 4, respectively. Additionally, we propose an alternative method to calculating the Ce anomalies of zircons using MS Excel-based software which is provided in the Supplementary data of this paper.
The complex trans -[RuNO(NH 3 ) 4 F]SiF 6 was synthesized in quantitative yield and the structure was characterized by X-ray diffraction and spectroscopic methods. The complex crystallizes in the non-centrosymmetric space group Pn . Hirshfeld surface analysis revealed that the dominant intermolecular interactions are of types H...F and F...O, which are likely to be responsible for the packing of the molecules in a non-centrosymmetric structure. Irradiation with blue light leads to the formation of Ru–ON (metastable state MS1) and Ru–η 2 -(NO) (metastable state MS2) bond isomers, as shown by IR and UV–Vis spectroscopy. The structural features of the MS1 isomer were elucidated by photocrystallography. The complex exhibits exceptionally good thermal stability of the metastable state MS1, such that it can be populated by light at 290–300 K, which is important for potential applications. The second harmonic (SH) emission can be generated by femtosecond-pulsed irradiation of the complex. The generated SH is rather efficient and stable under long-term exposure. Finally, since both metastable states and harmonic generation can be generated at room temperature, an attempt to drive the SH response by photoisomerization of the nitrosyl ligand was made and is discussed.
This work describes the module of the RiskPanel software system, performing risk analysis of multi-step computer attacks. The module is based on statistical analysis of actual computer attack precedents.

At the user's request the system calculates objective probability of information security risks, taking into account all possible multi-step attacks (i.e. possible combinations of known attacks). The estimation of probability is presented as an interval because we don't always have a full description of real attacks. The task of this work is described using the model-theoretic formalism. The first step is to build a knowledge base of computer attacks. The formal description of the knowledge base structure is made with the Description Logic. Formalization of estimated (fuzzy) judgments is made in the language of the Fuzzy Model Theory.

The article contains algorithms for calculation of probabilistic risk intervals and describes program implementation of the developed methods.
This article is devoted to the study of pressure pulsations behind the runner of a hydro turbine model caused by the precessing vortex core (PVC). Pressure pulsations are investigated under conditions of stationary load and transient modes of the hydro-turbine operation.

Studies were performed in model conditions on the aerodynamic setup. The map of pressure pulsations was built for stationary modes using acoustic sensors and served to find rotational speeds of the swirler and flow rates at which the PVC occurs. On the basis of the data presented by parametric dependences, the initial and final parameters of the transition process were chosen. In the article, a sudden (fast) transition from part-load regime to the best efficiency point and back was considered.

The characteristic times for the formation of PVC and the establishment of the flow regime when changing the controlling parameters of the installation have been determined using a continuous wavelet transform.
This paper discusses the physical nature and the numerical modeling of a novel approach of periodic structures for applications as photonic sensors. The sensing is based on the high sensitivity to the cover index change of the notch wavelength. This sensitivity is due to the effect of abnormal blocking of the guided wave propagating along the silicon wire with periodic strips overhead it through the silica buffer.

The structure sensing is numerically modeled by 2D and 3D finite difference time domain (FDTD) method, taking into account the waveguide dispersion. The modeling of the long structures (more than 1000 strips) is accomplished by the 2D method of lines (MoL) with a maximal implementation of the analytical feature of the method.

It is proved that the effect of abnormal blocking could be used for the construction of novel types of optical sensors.
The elemental composition of 100 oxalate type (only whewellite, weddellite and their mixture) urinary stones was determined by ICP OES. The calcium content varies from 130 to 320 g/kg; phosphorus – from 1.6 to 28 g/kg; sodium – from 0.54 to 8.7 g/kg; Ba, Fe, K, Li, Mg, Sr and Zn – from 0.0002 to 2.0 g/kg. The correlation analysis (Spearman rank correlation) showed a very weak tightness of the relationship between the elements of Ca/Li; a weak bond tightness for the pairs of elements Ba/Ca, Ba/Mg, Ba/Sr; Ca/Fe, Ca/Na, Ca/Sr; Fe/Mg, Fe/P, Fe/Sr, Fe/Zn; Li/Mg; Mg/Sr, Mg/Zn; P/Zn; average bond tightness for pairs of elements Ca/Mg, K/Na, Mg/P. All these correlations are positive.
In the present review the analysis of the world literature devoted to the problem of familial hypercholesterolemia at a young age was carried out. Its prevalence both on the territory of the Russian Federation and on the territory of the whole world is discussed. The problem of increased risk of age-dependent cardiovascular events is analyzed. The results of research examining the effectiveness of existing risk assessment scales at a young age, as well as the phenotypic diagnostic criteria, including DLCNC, Simon Broome, MEDPED and Japanese criteria are presented. An overview of studies aimed at investigation of the drug and non-drug therapy positive effect on cholesterol levels is given. Innovative methods of hypercholesterolemia correction were announced. The information on the topic from publications based on PubMed and Google Scholar data were used.