Hengzongshu/ArticleAgent huggingface dataset:
Objective. The aim of the study was to study biochemical factors of calcification in stable and unstable plaques of coronary arteries and in the blood of patients with severe coronary atherosclerosis, to find associations of biochemical factors of calcification with the development of unstable atherosclerotic plaque.

Materials and Methods. The study included 25 men aged 60,4±6,8 years who received coronary bypass surgery. In the course of the operation intraoperative indications in men were from coronary endarteriectomy (s) artery (a – d) and histological and biochemical analyses of the samples of the intima / media. Out of 85 fragments of intima / media of coronary arteries, 15 fragments of unchanged intima / media, 39 fragments of stable atheromatous plaque and 31 fragments of unstable plaque were determined. In homogenates of samples of intima / media (after measurement of protein by the method of Lowry) and in blood by ELISA were determined by biochemical factors of calcification: osteoprotegerin, osteocalcin, an osteopontin, osteonectin, as well as inflammatory factors (cytokines, chemokines).

Results. A significant direct correlation (Spearman coefficient =0.607, p<0.01) between the stages of atherosclerotic focus development to unstable plaque and the degree of calcification of atherosclerotic focus development samples was found. There was an increased content of osteocalcin in stable and unstable plaques by 3.3 times in comparison with the unchanged tissue of intima / media of coronary arteries, as well as in samples with small and dust-like, with coarse-grained calcifications in comparison with samples without calcifications by 2.8 and 2.1 times, respectively. According to multivariate logistic regression analysis, the relative risk of unstable atherosclerotic plaque in the coronary artery is associated with a reduced content of osteocalcin (OR=0.988, 95 % CI 0.978–0.999, p=0.028). Also, the relative risk of calcifications in the atherosclerotic plaque in the coronary artery is associated with an increased content of osteocalcin (OR=1,008, 95 % CI 1,001–1,015, p=0,035). In men with severe coronary atherosclerosis, a significant inverse correlation was found (Spearman coefficient –0.386, p=0.022) between the content of osteoprotegerin in the vascular wall and in the blood.
We compared three formulations of the discrete dipole approximation (DDA) for simulation of light scattering by particles with refractive indices $m=10+10i$, $0.1+i$, and $1.6+0.01i$. These formulations include the filtered coupled dipoles (FCD), the lattice dispersion relation (LDR) and the radiative reaction correction. We compared the number of iterations required for the convergence of the iterative solver (proportional to simulation time) and the accuracy of final results. We showed that the LDR performance for $m=10+10i$ is especially bad, while the FCD is a good option for all cases studied. Moreover, we analyzed the detailed structure of DDA errors and the spectrum of the DDA interaction matrix to understand the performance of the FCD. In particular, this spectrum, obtained with the FCD for particles smaller than the wavelength, falls into the bounds, physically implied for the spectrum of the infinite-dimensional integral scattering operator, contrary to two other DDA formulations. Finally, such extreme refractive indices can now be routinely simulated using modern desktop computers using the publicly available ADDA code, which includes an efficient implementation of the FCD.
The excitation function for the $pd\rightarrow$ $d p \pi^{0}$ reaction has been measured by WASA-at-COSY experiment with the aim of searching for $^{3}\hspace{-0.03cm}\mbox{He}$-$\eta$ mesic nuclei.

The measurement in the vicinity of $\eta$ meson production was performed using a ramped proton beam. The data analysis and interpretation was carried out with the assumption that the $\eta$-mesic Helium decays via the formation of an intermediate N$^{*}$(1535) resonance.

No direct signal of the $\eta$-mesic nucleus is observed in the excitation function. We determine a new improved upper limit for the total cross section for the bound state production and decay in the $pd\rightarrow$ $(^{3}\hspace{-0.03cm}\mbox{He}$-$\eta)_{bound} \rightarrow$ $d p \pi^{0}$ process. It varies between 13 nb to 24 nb for the bound state with width in the range $\Gamma \in (5,50)$ MeV.
Long-range exciton diffusion facilitates efficient exciton harvesting in a lightly-doped organic semiconductor crystal.
The authors investigate the historical fate of one of four construction mega-projects of Qin Shihuangdi, namely, Epang Palace which was supposed to become the worthy dwelling for the first unifier of the Celestial Empire. Construction workers erected the giant platform-stylobate and built three walls around it. During the Middle Ages (from the end of the Han dynasty and up to the Tang dynasty) it accommodated the military Echeng settlement. Within the same period of time, by the efforts of literati and, first of all, by prominent poet Du Mu (803–852) who wrote “The Ode on Epang Palace”, a myth was created about the wonderful residence of the Emperor with many features such as watchtowers, pavilions and galleries, and how all these beauties were destroyed by rebellions in the great fire.

Nevertheless, regular archaeological excavations conducted at the site during the period of 2002–2004 did not reveal any traces of such a fire.

The Palace wasn’t burned down – it was simply never constructed. Furthermore, though the huge base platform of the Palace was registered by UNESCO experts as the biggest palace building in the world, no further complicated constructions were found on its surface (though some evidence of preparatory works were reported, for example, the many pieces of roofing tiles that were lifted to the platform). The results of archaeological investigations of real Epang meant the death-warrant to false Epang that was built by local authorities as popular tourist attraction, means a source of money. It was ruined in 2012 and replaced with archaeological park where all construction works were to be based on scientific reconstruction.
In the present review the analysis of the world literature devoted to the study of metabolic disorders in the body and the risk of COVID-19 disease. It is known that metabolic syndrome is an independent risk factor for the severe course of new coronavirus infection. This review summarizes data on the mechanisms of metabolic dysfunction in a new coronavirus infection, analyzes the results of studies that investigated the issues of associations between the course of COVID-19 and various metabolic disorders, such as hyperglycemia and diabetes mellitus, dyslipidemia, obesity, non-alcoholic fatty liver disease, their severity, potential targets of therapy, predictors of the development of a severe course of new coronavirus infection are considered. These metabolic disorders increase the impairment of the immune system and make patients more susceptible to the development of infectious diseases, in particular, to infection with a new coronavirus infection. Taking into account the obtained data, it becomes obvious the need to identify and monitor patients with pre-existing metabolic diseases, as well as their development during and after COVID-19. The information on the topic from publications based on PubMed, PubMed Central, Scopus, Google Scholar, Medscape, UpYoDate, eLIBRARY.RU data were used.
Prior qEEG work lacked integration of cross-spectral information omitting important functional connectivity descriptors. Lack of geographical diversity precluded accounting for site-specific variance, increasing qEEG nuisance variance.

We ameliorate these weaknesses. (i) Create lifespan Riemannian multinational qEEG norms for cross-spectral tensors. These norms result from the HarMNqEEG project fostered by the Global Brain Consortium. We calculate the norms with data from 9 countries, 12 devices, and 14 studies, including 1564 subjects. Instead of raw data, only anonymized metadata and EEG cross-spectral tensors were shared. After visual and automatic quality control, developmental equations for the mean and standard deviation of qEEG traditional and Riemannian DPs were calculated using additive mixed-effects models. We demonstrate qEEG "batch effects" and provide methods to calculate harmonized z-scores. (ii) We also show that harmonized Riemannian norms produce z-scores with increased diagnostic accuracy predicting brain dysfunction produced by malnutrition in the first year of life and detecting COVID induced brain dysfunction. (iii) We offer open code and data to calculate different individual z-scores from the HarMNqEEG dataset.

These results contribute to developing bias-free, low-cost neuroimaging technologies applicable in various health settings.
Mesoporous tungsten-silicates, W-MMM-E, have been prepared following evaporation-induced self-assembly methodology and characterized by elemental analysis, XRD, N2 adsorption, STEM-HAADF (high angle annular dark field in scanning-TEM mode), DRS UV-vis, and Raman techniques. DRS UV-vis showed the presence of two types of tungsten oxo-species in W-MMM-E samples: isolated tetrahedrally and oligomeric octahedrally coordinated ones, with the ratio depending on the content of tungsten in the catalyst. Materials with lower W loading have a higher contribution from isolated species, regardless of the preparation method. W-MMM-E catalyzes selectively oxidize of a range of alkenes and organic sulfides, including bulky terpene or thianthrene molecules, using green aqueous H2O2. The selectivity of corresponding epoxides reached 85–99% in up to 80% alkene conversions, while sulfoxides formed with 84–90% selectivity in almost complete sulfide conversions and a 90–100% H2O2 utilization efficiency. The true heterogeneity of catalysis over W-MMM-E was proved by hot filtration tests. Leaching of inactive W species depended on the reaction conditions and initial W loading in the catalyst. After optimization of the catalyst system, it did not exceed 20 ppm and 3 ppm for epoxidation and sulfoxidation reactions, respectively. Elaborated catalysts could be easily retrieved by filtration and reused several times with maintenance of the catalytic behavior.
The modeling was based on the solution of 3D Euler equations and Fluent software was used as a main computational tool. The algorithm for local dynamic mesh adaptation to high gradients of pressure was applied. The initial stage of the explosion of condensed explosive was described with the help of 'Compressed balloon method'.

In the paper, numerical simulation of shock wave propagation in the vicinity of a standalone prism and a prism with a cavity in front of it was carried out. The numerical approach in Fluent based on combining inviscid gas dynamics methods and 'Compressed balloon method' was compared with the method which had been used by the authors earlier with the help of AUTODYN and which is based on the use of the hydrodynamic model of a material to describe state of detonation products.

The research allowed describing the characteristic stages of the blast in a semi-closed space, the structure of secondary shock waves and their interaction with obstacles. For the problem of shock wave propagation in the vicinity of standalone prism the comparison of the simulation results obtained using both the methods with the experimental data was performed on the dependence of static pressure and effective momentum on time for the characteristic points located on prism walls.
Создание различных ономастических баз данных, каталогов, атласов относятся к актуальным задачам современной науки.

В отличие от топонимических исследований, в настоящее время нелегко получить доступ к идеальным базам для исследования антропонимов, поскольку личные имена и личные данные являются приватной информацией
Liquid phase levulinic acid hydrogenation into γ-valerolactone in 1,4-dioxane as a solvent (165°C, 20 bar) was studied over a range of Ru monometallic catalysts using mesoporous carbon material Sibunit as a support. Сarbon supported colloidal Ru NPs were not studied earlier in levulinic acid hydrogenation.

In addition to the catalyst prepared by impregnation with RuCl3∙nH2O (0.1 M) followed by reduction in H2, size-controlled Ru(NPs)/Sibunit catalysts were synthesized by immobilization of polyvinylpyrrolidone (PVP) stabilized Ru nanoparticles (NPs) (dRu=2.4 nm). The catalysts were characterized by TEM, XRF, and N2 physisorption to compare their physical chemical properties

Activity of colloidal Ru(NPs)/Sibunit catalysts was found to be lower than that of impregnated Ru/Sibunit which could be attributed to hampering effect of PVP. However, colloidal Ru(NPs)/Sibunit purified by thermal treatment in air (180°C) followed by reduction in H2 (400°C) exhibited the same activity as impregnated one yielding 93% γ-valerolactone at 100% levulinic acid conversion. Applicability of supported PVP-assisted colloidal Ru NPs in hydrogenation of levulinic acid illustrates a potential to prepare more efficient catalysts for this reaction with a desired particle size.
Background. Active ribosomal genes and DNA repair genes play an important role in restoring genome integrity. Therefore we were studied relationship of active ribosomal genes dose and DNA repair genes polymorphisms with high level of chromosomal disorders in miners.

Materials and methods. The DNA damage level was assessed using chromosomal aberrations (CA) at 288 coal miners and 676 men in the control group. The dose of active ribosomal gene (AcRG) has been analyzed using Ag-NORS staining regions of chromosomes and cytogenetic semi-quantitative evaluation method. Real-time PCR and allele-specific PCR techniques were used to analyze polymorphic variants of the XPG (rs17655), XPD (rs13181), XRCC2 (rs3218536), and XRCC3 (rs861539) genes.

Results. A statistically significant (p = 0.0001) increase of the СА level at miners was found in comparison with the control group. The association XPD 2251TG locus with increasing CA level is revealed of in recessive inheritance model (padj = 0.0001). The association XPG 3310GC locus with increasing СА level is revealed at the smoking workers (padj = 0.017). An average dose of AcRG was registered a statistically significant increase in the frequency of single fragments (p = 0.016) at the miners. Conclusion. The obtained data on associations of chromosomal aberrations with different variants of DNA repair genes and the dose of active ribosomal genes are useful for the formation of high-risk groups.
Inter-individual differences in many behaviors are partly due to genetic differences, but the identification of the genes and variants that influence behavior remains challenging.

Here, we studied an F2 intercross of two outbred lines of rats selected for tame and aggressive behavior towards humans for more than 64 generations. By using a mapping approach that is able to identify genetic loci segregating within the lines, we identified four times more loci influencing tameness and aggression than by an approach that assumes fixation of causative alleles, suggesting that many causative loci were not driven to fixation by the selection. We used RNA sequencing in 150 F2 animals to identify hundreds of loci that influence brain gene expression. Several of these loci colocalize with tameness loci and may reflect the same genetic variants. Through analyses of correlations between allele effects on behavior and gene expression, differential expression between the tame and aggressive rat selection lines, and correlations between gene expression and tameness in F2 animals,

we identify the genes Gltscr2, Lgi4, Zfp40 and Slc17a7 as candidate contributors to the strikingly different behavior of the tame and aggressive animals.
We describe the model for excitation of ocean surface gravity waves by the wind blowing away from the shore.

Numerical simulation shows that wave turbulence behaviour can be split in time into two different physical regimes: classical and non-classical one. The classical regime corresponds to self-similar solution developing for the characteristic times defined by ratio of the channel width to characteristic advection velocity of the wave field.

The non-classical regime is happening later in time when the energy starts to reflect from the opposite boundary condition and corresponds to energy advection against the wind. It exhibits itself in waves generating predominantly parallel to the shore line, tending to slant toward the shore, as approaching to the beginning of the fetch, at 15 degrees.
(1) Background: Developments in accelerator-based neutron sources moved boron neutron capture therapy (BNCT) to the next phase, where new neutron radiation parameters had to be studied for the treatment of cancers, including brain tumors. We aimed to further improve accelerator-BNCT efficacy by optimizing dosimetry control, beam parameters, and combinations of boronophenylalanine (BPA) and sodium borocaptate (BSH) administration in U87MG xenograft-bearing immunodeficient mice with two different tumor locations. (2) Methods: The study included two sets of experiments. In Experiment #1, BPA only and single or double irradiation in higher doses were used, while, in Experiment #2, BPA and BSH combinations and single or double irradiation with dosage adjustment were analyzed. Mice without treatment or irradiation after BPA or BPA+BSH injection were used as controls. (3) Results: Irradiation parameter adjustment and BPA and BSH combination led to 80–83% tumor-growth inhibition index scores, irradiation:BNCT ratios of 1:2, and increases in animal life expectancy from 9 to 107 days. (4) Conclusions: Adjustments in dosimetry control, calculation of irradiation doses, and combined use of two 10B compounds allowed for BNCT optimization that will be useful in the development of clinical-trial protocols for accelerator-based BNCT.
Nitrogen abundance is one of the most uncertain among all elements in the Earth's interior. Recent data indicate an affinity between Fe‐nitrides and Fe‐carbides in the Earth's mantle and inner core. In this work P‐V‐T equations of state of ε‐Fe 3 N 0.8 and ε‐Fe 3 N 1.26 (which is close to Fe 7 N 3 ) have been determined using a combination of multianvil and synchrotron radiation techniques at pressures up to 30 GPa and temperatures up to 1473 K. A fit of the P‐V‐T data to the Vinet‐Rydberg and Mie‐Grüneisen‐Debye equations of state yields the following thermoelastic parameters for the ε‐Fe 3 N 0.8 : V 0 = 81.44(2) Å 3 , K T 0 = 157(3) GPa, K T ′ = 5.3 (fixed), θ 0 = 555 K (fixed), γ 0 = 1.83(1), and q = 1.34(18). For ε‐Fe 3 N 1.26 we obtained V 0 = 86.18(2) Å3, K T 0 = 163(2) GPa, K T ′ = 5.3(2), θ 0 = 562(90) K, γ 0 = 1.85(2), and q = 0.55(24). It is likely that all presumably paramagnetic ε‐Fe 3 N x with x = 0.75–1.5 have similar thermoelastic properties with a minor increase of the bulk modulus with increasing N content. The melting temperature of ε‐Fe 3 N x increases from approximately 1473 to 1573 K in the pressure range from 5 to 30 GPa. We also determined a preliminary equation of state for γ‐Fe 4 N y and calculated y = 0.35(2) from the data at 20–30 GPa. Combining the results with a recent experimental study on the stability of β‐Fe 7 N 3 , isostructural with Fe 7 C 3 , and a theoretical study of the magnetic transitions in ε‐Fe 3 N x , we estimate the density of Fe‐nitrides at the Earth's inner core conditions. Our results indicate that at 5000–6000 K, 2.0–3.2 wt % N can explain the density deficit in Earth's inner core.
Nonlinear interaction of a low density electron beam with a uniform plasma is studied using two-dimensional particle-in-cell (PIC) simulations. We focus on formation of coherent phase space structures in the case, when a wide two-dimensional wave spectrum is driven unstable, and we also study how nonlinear evolution of these structures is affected by the external magnetic field. In the case of isotropic plasma, nonlinear buildup of filamentation modes due to the combined effects of two-stream and oblique instabilities is found to exist and growth mechanisms of secondary instabilities destroying the BGK--type nonlinear wave are identified. In the weak magnetic field, the energy of beam-excited plasma waves at the nonlinear stage of beam-plasma interaction goes predominantly to the short-wavelength upper-hybrid waves propagating parallel to the magnetic field, whereas in the strong magnetic field the spectral energy is transferred to the electrostatic whistlers with oblique propagation.
Astronomical observations of recent years show that the universe at high redshifts about ten is densely populated by the early formed objects: bright galaxies, quasars, gamma-bursters, and contains a lot of metals and dust.Such rich early formed varieties have not been expected in the standard model of formation of astrophysical objects.There is serious tension between the standard theory and observations.We describe the model which naturally relaxes this tension and nicely fits the data.The model naturally leads to creation of cosmologically significant antimatter which may be abundant even in the Galaxy.Phenomenological consequences of our scenario and possibility of distant registration of antimatter are discussed.
In the present work, we study and compare the structure and sensing properties of thin films of unsubstituted palladium phthalocyanine (PdPc) and hexadecafluorosubstituted palladium phthalocyanine (PdPcF16).

Thin films of PdPc and PdPcF16 were obtained by the method of organic molecular beam deposition, and their structure was studied using UV–visible spectroscopy, X-ray diffraction, and atomic force microscopy techniques. The electrical sensor response of PdPc films toward ammonia and hydrogen was investigated and compared with that of PdPcF16 films.

The nature of interaction between the phthalocyanines films and some gaseous analyte molecules has been clarified using quantum chemical (DFT) calculations.
The lliquid films are applied in the various equipments intended for an intensification of heat and mass transfer processes. Heat transfer can also be intensifying by the gas flow above the liquid surface; these processes take a place at two-phase flows in mini- and microchannels.

This study deals with the heat transfer in a locally heated liquid film of constant thickness h. The film is supposed to flow along the heated plate having constant temperature TW under the action of gravity and a gas flow. Influence of a gas flow on a velocity profile in the liquid is considered through shear stress on an interface. Coefficient of heat exchange and shear stress on a film surface suppose be set. Equation of the energy for a liquid film is solved by Galerkin technique which is special case of the weighed residuals method (WRM). Applying of Galerkin technique to this problem allows calculating the temperature in a liquid analytically for arbitrary a temperature profile in initial cross-section of a film. For initial temperature profile, gained from the analytical solution the temperature field is calculated. Results of these calculations are compared to results of numerical solution of the energy equation by finite-difference method.

This comparison has shown the good agreement both for a falling film, and for cocurrent or countercurrent gas flow.
Due to the heightened interest in BigData the described cipher is used to encrypt big volumes of data in cloud storage services.

The article focuses on the description of a new block cipher.

The main advantages of the given cipher are the ease of implementation and the possibility of probabilistic encryption. This means that the text encryption will be different when the key is the same and the data is the same. So, the strength of the encryption is improved. Additionally, the ciphered message size can be hardly predicted.