Hengzongshu/ArticleAgent huggingface dataset:
The article focuses on the anti-religious policy of the Soviet Union adopted in relation to believers and religious organizations.

The reasons for the persecution of religion, churches and believers, such as the conceptual framework of Marxist ideology, desire for total power, and creation of an ideocratic state are analyzed. The main stages of the anti-religious campaign led by the Bolshevik government are determined. Major anti-religious practices, such as legal restriction of all forms of religious life, discrimination against the clergy and believers, atheist education and anti-religious propaganda work are studied.

It may be concluded that persecution of believers is a systemic feature of a totalitarian regime.
A bstract The product of the electronic width of the J/ψ meson and the branching fractions of its decay to hadrons and electrons has been measured using the KEDR detector at the VEPP-4M e + e − collider. The obtained values are $$ \begin{array}{c}\hfill {\Gamma}_{ee}\left(J/\psi \right)=5.550\pm 0.056\pm 0.089\kern0.5em \mathrm{keV},\hfill \\ {}\hfill {\Gamma}_{ee}\left(J/\psi \right)\cdotp {\mathrm{\mathcal{B}}}_{\mathrm{hadrons}}\left(J/\psi \right)=4.884\pm 0.048\pm 0.078\kern0.5em \mathrm{keV},\hfill \\ {}\hfill {\Gamma}_{ee}\left(J/\psi \right)\cdotp {\mathrm{\mathcal{B}}}_{ee}\left(J/\psi \right)=0.3331\pm 0.0066\pm 0.0040\kern0.5em \mathrm{keV}.\hfill \end{array} $$ ΓeeJ/ψ=5.550±0.056±0.089keV,ΓeeJ/ψ·ℬhadronsJ/ψ=4.884±0.048±0.078keV,ΓeeJ/ψ·ℬeeJ/ψ=0.3331±0.0066±0.0040keV. The uncertainties shown are statistical and systematic, respectively. Using the result presented and the world-average value of the electronic branching fraction, one obtains the total width of the J/ψ meson: $$ \Gamma =92.94\pm 1.83\kern0.5em \mathrm{keV}. $$ Γ=92.94±1.83keV. These results are consistent with the previous experiments.
PARP-1 synthesizes long poly(ADP-ribose) chains (PAR) at DNA damage sites to recruit DNA repair factors. Among proteins relocated on damaged DNA, the RNA-binding protein FUS is one of the most abundant, raising the issue about its involvement in DNA repair. Here, we reconstituted the PARP-1/PAR/DNA system in vitro and analyzed at the single-molecule level the role of FUS. We demonstrate successively the dissociation of FUS from mRNA, its recruitment at DNA damage sites through its binding to PAR, and the assembly of damaged DNA-rich compartments. PARG, an enzyme family that hydrolyzes PAR, is sufficient to dissociate damaged DNA-rich compartments in vitro and initiates the nucleocytoplasmic shuttling of FUS in cells. We anticipate that, consistent with previous models, FUS facilitates DNA repair through the transient compartmentalization of DNA damage sites. The nucleocytoplasmic shuttling of FUS after the PARG-mediated compartment dissociation may participate in the formation of cytoplasmic FUS aggregates.
Poly(ADP-ribose) polymerases (PARPs) act as DNA break sensors and catalyze the synthesis of polymers of ADP-ribose (PAR) covalently attached to acceptor proteins at DNA damage sites. It has been demonstrated that both mammalian PARP1 and PARP2 PARylate double-strand break termini in DNA oligonucleotide duplexes in vitro.

Here, we show that mammalian PARP2 and PARP3 can PARylate and mono(ADP-ribosyl)ate (MARylate), respectively, 5'- and 3'-terminal phosphate residues at double- and single-strand break termini of a DNA molecule containing multiple strand breaks. According to DNA substrate specificity of PARP3 and PARP2, we propose a putative mechanistic model of PARP-catalyzed strand break-oriented ADP-ribosylation of DNA termini. Finally, we show an effective PARP3- or PARP2-catalyzed ADP-ribosylation of high-molecular-weight (∼3-kb) DNA molecules, PARP-mediated DNA PARylation in cell-free extracts and a persisting signal of anti-PAR antibodies in a serially purified genomic DNA from bleomycin-treated poly(ADP-ribose) glycohydrolase-depleted HeLa cells.

PARP3-catalyzed DNA MARylation can be considered a new type of reversible post-replicative DNA modification. Notably, PARP-mediated DNA ADP-ribosylation can be more effective than PARPs' auto-ADP-ribosylation depending on the DNA substrates and reaction conditions used. These results suggest that certain types of complex DNA breaks can be effectively ADP-ribosylated by PARPs in cellular response to DNA damage.
Post-translational modifications diversify protein functions and dynamically coordinate their signalling networks, influencing most aspects of cell physiology. Nevertheless, their genetic regulation or influence on complex traits is not fully understood.

Here, we compare the genetic regulation of the same PTM of two proteins – glycosylation of transferrin and immunoglobulin G (IgG). By performing genome-wide association analysis of transferrin glycosylation, we identify 10 significantly associated loci, 9 of which were not reported previously. Comparing these with IgG glycosylation-associated genes, we note protein-specific associations with genes encoding glycosylation enzymes (transferrin - MGAT5 , ST3GAL4 , B3GAT1 ; IgG - MGAT3 , ST6GAL1 ), as well as shared associations ( FUT6 , FUT8 ). Colocalisation analyses of the latter suggest that different causal variants in the FUT genes regulate fucosylation of the two proteins.

Glycosylation of these proteins is thus genetically regulated by both shared and protein-specific mechanisms.
The progress of medicine, science, technology, education, and culture improves, year by year, quality of life and life expectancy of the populace. The modern human has a chance to further improve the quality and duration of his/her life and the lives of his/her loved ones by bringing their lifestyle in line with their sequenced individual genomes.

With this in mind, one of genome-based developments at the junction of personalized medicine and bioinformatics will be considered in this work, where we used two Web services: (i) SNP_TATA_Comparator to search for alleles with a single nucleotide polymorphism (SNP) that alters the affinity of TATA-binding protein (TBP) for the TATA boxes of human gene promoters and (ii) PubMed to look for retrospective clinical reviews on changes in physiological indicators of reproductive potential in carriers of these alleles.
Magnetite (Fe 3 O 4 ) nanoparticles are widely used in microwave components, such as microwave absorbers and anti-reflection coatings. Their magnetic properties are important for these applications. In this work, the weak magnetic field created by the Fe 3 O 4 nanoparticles was estimated using a coherent-spectroscopy all-optical method for measurement of weak magnetic fields. Both the magnitude and the direction of the magnetic field were evaluated through the position and amplitude of a magneto-optical resonance obtained in a paraffin-coated sensor cell containing Rb vapors. A pump-probe scheme was used to prepare a high-contrast magneto-optical resonance. Different possible geometries related to this concept are discussed, including sensor miniaturization.
Drive particle beams in linear or weakly nonlinear regimes of the plasma wakefield accelerator quickly reach a radial equilibrium with the wakefield, which is described in detail for the first time. The equilibrium beam state and self-consistent wakefields are obtained by combining analytical relationships, numerical integration, and first-principle simulations. In the equilibrium state, the beam density is strongly peaked near the axis, the beam radius is constant along the beam, and longitudinal variation of the focusing strength is balanced by varying beam emittance. The transverse momentum distribution of beam particles depends on the observation radius and is neither separable, nor Gaussian.
The paper discusses argumentation in popular science articles written by scholars. The authors focus on argumentative framework, which is presented by opposition of an expert’s judgment (argument from expert opinion) and a common, “naive” view (one from popular opinion).

The framework consists of a thesis being opposed (by a subject of common sense); its authorization marker; an opposing structural constant/propositional connective; an expert’s thesis; its authorization marker; general conclusion. In summary, this paper argues that the elements of the argumentative framework can be explicit, implicit, or be presented grammatically. Text analysis of popular science articles leads to the following conclusions.

(1) The opposed thesis and opposing link are typically explicit. (2) The subject of common sense can be represented by lexical and syntactic expressions of indefinite-personality, impersonality together with unreal mood and epistemic modality of uncertain knowledge (One would think…; smth may seem…; many noticed that…) etc. (3) An expert’s thesis, as a rule, is presented as a negation of the opposed statement. (4) An authorization marker of the expert’s opinion is consistently implicit. The reason is that an expert writes the entire text (except for parts with authorization markers), and in this case the additional expression of this fact is optional. (5) Normally, the general conclusion is the same as the expert’s thesis, therefore it is rarely if ever explicit.
The article presents the results of field experiments on the influence of the natural frequencies in the soil and constant exposure to the outside over time for stability engineering structures. It is shown that the frequency-amplitude spectrum of the natural oscillations of the investigated multi-storey residential building does not change over time.
Below is data on the microbial diversity of natural organic matter from the Dispersion Train of Sulfide Tailings (northern Salaire Ridge, southwestern Siberia, Russia, Ursk Village).

Data was obtained using 16s rRNA amplicon directed metagenomic sequencing on Illumina MiSeq. The raw sequence data used for analysis is available in NCBI under the Sequence Read Archive (SRA) with BioProject No. PRJNA670045 and SRA accession number SRX9314152, SRX9314376.

The data sequences of the 16s rRNA gene are presented at the links MW142408-MW142413, MW142414-MW142447.
The paper examines the foundations of sponsorship research in order for better understanding the conceptual and theoretical foundations that have underpinned the development of sponsorship to our date. It tackles this field of study fr om a historical perspective and analyses available scholarly research, tracks back its development and consequently projects future trends, tries to highlight the gaps found in academic literature and to cite problems concerning the sponsorship application. What this study does reveal, is that sponsorship is still following a positive trend, as validated by our content analysis and financial figures, and in accordance with the results of previous studies in this field. However, the problems are still various and diverse, some are of evaluation nature, others purely academic or related to function. When it comes to the Russian market, the lack of scholarly research is notable. In this context, sports sponsorship should not be seen and limited to sports economics or marketing. There are broader geopolitical and strategic dimensions, wh ere sports sponsorship plays the role of a soft power tool. Therefore, there is a need for the development of this field, for the trend analyses, which are not common in academic research to date, not only for Russia but also globally.
Aim ― To reveal the results of the condition of the bone marrow mononuclear cells (BM-MNCs) with erythropoietin (Epo).

Material and Methods ― There were 30-ty patients with coronary artery disease (CAD) enrolled in this study during 2016-2017 years. 95% were men. All were in angina NYHA class II-III. Hypertension presented in 90%, peripheral atherosclerosis in 60%. BM-MNCs were obtained by centrifugation of bone marrow aspirate on Ficoll-Paque, washed, and then preconditioned with Epo. Phenotype, cell cycle, cell death, proliferation, migration, and tube formation before, and after precondition BM-MNCs with Epo were done.

Results ― In this study, we observed the presence in cellular graft of the hematopoietic stem cells (HSCs), and endothelial progenitor cells (EPCs) at the different stage of maturation/differentiation, and mesenchymal stem cells (MSCs). Precondition BM-MNCs with Epo increased number of HSCs carrying erythropoietin receptor (EpoR), and EPCs carrying CD184. Also, Epo detained СВ34+ cells in a rest phase of cell cycle (G0G1). Condition media from BM-MNCs treated with Epo augment tube formation and wound healing by EA.hy 929. Conclusion ― Epo in vitro increased number of the stem cells carrying EpoR and CD184, and increased accumulation of CD34+ cell in G0G1 phase of cell cycle, and induced production of proangiogenic factor by BM-MNCs. Further investigation is needed to assess the type of cytokines produced by BM-MNCs after condition with Epo.
A small family composed of BRI1 KINASE INHIBITOR1 (BKI1) and MEMBRANE‐ASSOCIATED KINASE REGULATORS (MAKRs) has recently captured the attention of plant biologists, due to their involvement in developmental processes downstream of hormones and Receptor‐Like Kinases (RLK) signalling. BKI1/MAKRs are intrinsically disordered proteins (so‐called unstructured proteins) and as such lack specific domains. Instead, they are defined by the presence of two conserved linear motifs involved in the interaction with lipids and proteins, respectively.

Here, we first relate the discovery of the MAKR gene family. Then, we review the individual function of characterized family members and discuss their shared and specific modes of action. Finally, we explore and summarize the structural, comparative and functional genomics data available on this gene family.

Together, this review aims at building a comprehensive reference about BKI1/MAKR protein function in plants.
We search for lepton-flavor-violating and lepton-number-violating tau decays into a lepton (l = electron or muon) and two charged mesons (h, h' = pion or Kaon)

using 854 fb^{-1} of data collected with the Belle detector at the KEKB asymmetric-energy e^+e^- collider

We obtain 90% confidence level upper limits on the tau to lhh' branching fractions in the range (2.0-8.4)*10^{-8}. These results improve upon our previously published upper limits by factors of about 1.8 on average.
Jet flows are extensively used in various practical applications. Presently, the development of technical equipment where jets are employed is connected with the improvement and optimization of different methods of flow control.

In the paper, an experimental investigation of the turbulent structure of forced bubbly free and impinging jets was carried out by means of PIV and PFBI techniques. PIV was applied to measure velocity distributions and turbulent characteristics in the continuous phase, while PFBI approach was applied to visualize bubbles in the flow and evaluate their sizes. The flow was studied at the Reynolds number of 12,500 and three void fractions β = 0, 1 and 2% for forced conditions St = 0.5. The mean air bubble diameter was estimated to be roughly 0.8 mm for all β.

It was revealed that in the free jet the air bubbles and flow pulsations reduces substantially the longitudinal dimension of the jet core. In two-phase flow with forcing distribution of turbulence kinetic energy was similar to one-phase case but maximum value was two and a half times higher then for one-phase unforced jet. In the impinging jet flow, the bubbles produced a maximum of the turbulence kinetic energy near the wall, which increased two and a half times in forced conditions.
The search for variants of mitochondrial genome associated with atherosclerosis, in particular, with carotid intima-media thickness (cIMT), is necessary to understand the role of the damage of mitochondrial genome in the development of atherosclerosis. Such data can be useful to provide novel genetic markers of predisposition to atherosclerosis and molecular targets for further development of technologies aimed to prevent age-related degenerative pathologies. Data presented in this article demonstrate the association of several heteroplasmic variants of mitochondrial DNA (mtDNA) previously described as proatherogenic ones with cIMT in 251 participants (190 participants from Novosibirsk, Russia, and 61 participant from Almaty, Kazakhstan). It was shown that the occurrence of some variants of mitochondrial genome is different in samples derived from Russian and Kazakh populations; the level of mitochondrial heteroplasmy m.13513G > A correlates negatively with mean cIMT in both Russian and Kazakh participants.
The article describes two main types of investments in the intellectual property market in Russia - direct and venture, the prevailing share of state-owned venture investments over private is shown.

The picture of high-tech investments is presented.

The factors affecting the investment attractiveness of the intellectual product are named, the characteristics of the main trends in the venture investment market are given.
DNA polymerase β (Polβ) is considered the main repair DNA polymerase involved in the base excision repair (BER) pathway, which plays an important part in the repair of damaged DNA bases usually resulting from alkylation or oxidation. In general, BER involves consecutive actions of DNA glycosylases, AP endonucleases, DNA polymerases, and DNA ligases. It is known that protein-protein interactions of Polβ with enzymes from the BER pathway increase the efficiency of damaged base repair in DNA. However natural single-nucleotide polymorphisms can lead to a substitution of functionally significant amino acid residues and therefore affect the catalytic activity of the enzyme and the accuracy of Polβ action. Up-to-date databases contain information about more than 8000 SNPs in the gene of Polβ. This review summarizes data on the in silico prediction of the effects of Polβ SNPs on DNA repair efficacy; available data on cancers associated with SNPs of Polβ; and experimentally tested variants of Polβ. Analysis of the literature indicates that amino acid substitutions could be important for the maintenance of the native structure of Polβ and contacts with DNA; others affect the catalytic activity of the enzyme or play a part in the precise and correct attachment of the required nucleotide triphosphate. Moreover, the amino acid substitutions in Polβ can disturb interactions with enzymes involved in BER, while the enzymatic activity of the polymorphic variant may not differ significantly from that of the wild-type enzyme. Therefore, investigation regarding the effect of Polβ natural variants occurring in the human population on enzymatic activity and protein-protein interactions is an urgent scientific task.
Recent experimental and computational efforts have provided large data sets describing three-dimensional organization of mouse and human genomes and showed the interconnection between the expression profile, epigenetic state, and spatial interactions of loci. These interconnections were utilized to infer the spatial organization of chromatin, including enhancer–promoter contacts, from one-dimensional epigenetic marks. Here, we show that the predictive power of some of these algorithms is overestimated due to peculiar properties of the biological data. We propose an alternative approach, which provides high-quality predictions of chromatin interactions using information on gene expression and CTCF-binding alone. Using multiple metrics, we confirmed that our algorithm could efficiently predict the three-dimensional architecture of both normal and rearranged genomes.
Specific projects initiated by higher school and high-tech business is the scientific and technological basis of the Program for the development of Novosibirsk Scientific Center (Akademgorodok 2.0) as a territory with high concentration of research and development institutions.

The article presents general information on scientific, infrastructural and innovative projects of the Program, their classification by key indicators, promotion and scientific-organizational support of projects.

The article proposes the measures to make higher education in Novosibirsk more attractive and competitive in both international and Russian education services markets as the most important direction of implementation of the Program 'Akademgorodok 2.0'. The work focuses on the necessity to form new educational programs and their coordination with the promising research and scientific developments implemented within the framework of the Program 'Akademgorodok 2.0'. The authors express their position on the proposals to organize 'Big NSU' by including a number of academic institutions of the NSC of the Russian Academy of Sciences.
The photoluminescence properties of the intensive defect-related emission in heavily doped AlxGal-xN:Si layers with x > 0.5 have been investigated by photoluminescence (PL) spectroscopy. The PL band in AlN was attributed to donor-acceptor (DA) transitions. At the lowest Al content, the impurity band merges with the conduction band and DA transitions are replaced by electron-acceptor transitions involving the same acceptor. The energy structure of recombination centers was obtained using the model of configuration coordinates for Al0.67Ga0.33N.
We report a measurement of ${D}^{0}\text{\ensuremath{-}}{\overline{D}}^{0}$ mixing parameters and a search for indirect $CP$ violation through a time-dependent amplitude analysis of ${D}^{0}\ensuremath{\rightarrow}{K}_{S}^{0}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ decays. The results are based on $921\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of data accumulated with the Belle detector at the KEKB asymmetric-energy ${e}^{+}{e}^{\ensuremath{-}}$ collider. Assuming $CP$ conservation, we measure the mixing parameters $x=(0.56\ifmmode\pm\else\textpm\fi{}{0.19}_{\ensuremath{-}0.09\ensuremath{-}0.09}^{+0.03+0.06})%$ and $y=(0.30\ifmmode\pm\else\textpm\fi{}\phantom{\rule{0ex}{0ex}}{0.15}_{\ensuremath{-}0.05\ensuremath{-}0.06}^{+0.04+0.03})%$, where the errors are statistical, experimental systematic, and systematic due to the amplitude model, respectively. With $CP$ violation allowed, the parameters $|q/p|={0.90}_{\ensuremath{-}0.15\ensuremath{-}0.04\ensuremath{-}0.05}^{+0.16+0.05+0.06}$ and $\mathrm{arg}(q/p)=(\ensuremath{-}6\ifmmode\pm\else\textpm\fi{}11\ifmmode\pm\else\textpm\fi{}{3}_{\ensuremath{-}4}^{+3})\ifmmode^\circ\else\textdegree\fi{}$ are found to be consistent with conservation of $CP$ symmetry in mixing and in the interference between mixing and decay, respectively.
The ideas of neurodiversity are more and more popular today and could be considered at different levels of analysis. At first, neurodiversity is the original idea that the characteristics of an individual`s brain structure affect the features of his way of thinking and behavior. Secondly, it is the neurodiversity paradigm. Its proponents believe that many psychiatric diagnoses are socially constructed. The neurodifferent brain is considered not as a pathology, but as a feature that causes problems only because of the cruelty and inappropriateness of the world of neurotypical. The paradigm is especially widely used by individuals with ASD. Researchers note logical contradictions in the paradigm. It is a socio-cultural construct which is demanded by modern society and mass culture.

Analyzing features and manifestations of this community, author comes to the conclusion that the culture of neurodiversity is opposed to the dominant one.

Different movements against oppression are spreading to ever wider contexts. The media image of individuals with ASD is associated with the demand for traits of individualism, specificity, distinction and non-systemic in modern society. Consequently, the media create a romanticized image of the autistic, which leads to the popularity of the paradigm of neurodiversity. Finally, active supporters of the neurodiversity paradigm are representatives of a specific culture that has a special language, symbols, identity, values, communicative preferences, etc. There is a paradox: the paradigm of neurodiversity is in line with trends of modernity, while the neurodiversity culture acts as a counterculture.