Hengzongshu/ArticleAgent huggingface dataset:
Being discovered almost a century ago, this powerful synthetic method can be used for construction of new materials for organic electronics – one of the modern challenges of organic chemistry.

The Front Cover shows a variety of dienophiles used in the synthesis of functionalized polycyclic aromatic hydrocarbons over the past decade via the Diels-Alder reaction.

Linear or angular, planar or curved, molecular or polymeric – the product scope is vast and will broaden even more with further development of new diene and dienophile components.
while experiments for the case of a supersonic leading edge are a continuation of previous studies

The experiments were fulfilled in the low nose supersonic wind tunnel T-325 of Khristianovich Institute of Theoretical and Applied Mechanics on the models with supersonic or subsonic leading edges. The transition location was determined using a constant temperature hot-wire anemometer.

It was obtained that transition take place parallel to the leading edge for both models. The destabilizing effect of the surface curvature of the model on the position of the laminar-turbulent transition for the case of a supersonic leading edge was confirmed. This experimental data is the room for further investigation.
The article presents the higher mathematics chair of the physics department at Novosibirsk State University, describing the history of its creation, its traditions

methods used by its lecturers

some general information about the staff and the courses taught
Researches are connected with studying of transformational processes intra corporate of management practices in the Russian companies and their subsequent institutionalization.

Preliminary results showed that in the companies there is a standard set of organizational routines which part are information, and administrative routines, routines of the power of the founder, genetic, institutional and development routines. During research statistically significant connection between types of organizational structures, the sizes of the organization, information processing and administrative practices is established.

It is revealed as change of approaches to management of the organization can affect a corruption component.
Daily agonistic interactions of mice are an effective experimental approach to elucidate the molecular mechanisms underlying the excitation of the brain neurons and the formation of alternative social behavior patterns.

An RNA-Seq analysis was used to compare the ventral tegmental area (VTA) transcriptome profiles for three groups of male C57BL/6J mice: winners, a group of chronically winning mice, losers, a group of chronically defeated mice, and controls.

The data obtained show that both winners and defeated mice experience stress, which however, has a more drastic effect on defeated animals causing more significant changes in the levels of gene transcription. Four genes (Nrgn, Ercc2, Otx2, and Six3) changed their VTA expression profiles in opposite directions in winners and defeated mice. It was first shown that Nrgn (neurogranin) expression was highly correlated with the expression of the genes involved in dopamine synthesis and transport (Th, Ddc, Slc6a3, and Drd2) in the VTA of defeated mice but not in winners. The obtained network of 31 coregulated genes, encoding proteins associated with nervous system development (including 24 genes associated with the generation of neurons), may be potentially useful for studying their role in the VTA dopaminergic neurons maturation under the influence of social stress.
Poly(ADP-ribosyl)ation (PARylation) is posttranslational modification of proteins by linear or branched chains of ADP-ribose units, originating from NAD+. The central enzyme for PAR production in cells and the main target of poly(ADP-ribosyl)ation during DNA damage is poly(ADP-ribose) polymerase 1 (PARP1). PARP1 ability to function as a catalytic and acceptor protein simultaneously made a considerable contribution to accumulation of contradictory data.

This topic is directly related to other questions, such as the stoichiometry of PARP1 molecules in auto-modification reaction, direction of the chain growth during PAR elongation and functional coupling of PARP1 with PARylation targets. Besides DNA damage necessary for the folding of catalytically active PARP1, other mechanisms appear to be required for the relevant intensity and specificity of PARylation reaction. Indeed, in recent years, PARP research has been enriched by the discovery of novel PARP1 interaction partners modulating its enzymatic activity.

Understanding the details of PARP1 catalytic mechanism and its regulation is especially important in light of PARP-targeted therapy and may significantly aid to PARP inhibitors drug design. In this review we summarize old and up-to-date literature to clarify several points concerning PARylation mechanism and discuss different ways for regulation of PAR synthesis by accessory proteins reported thus far.
An inversion of surface waves dispersion curves is a non-unique and ill-conditioned problem. The inversion result has a probabilistic nature, which becomes apparent when simultaneously restoring the shear wave (S-wave) velocity and layer thickness. Therefore, the problem of uncertainty quantification is relevant. Existing methods through deterministic or global optimization approaches of uncertainty quantification via posterior probability density (PPD) of the model parameters are not computationally efficient since they demand multiple solutions of the inverse problem.

We present an alternative method based on a multi-layer fully connected artificial neural network (ANN). We improve the current uni-modal approach, which is known from publications, to multi-modal inversion. We use the Cox's and Teague's algorithm to determine optimal parametrization (number of layers) and the ranges of possible model parameters. We uniformly draw training data sets within estimated ranges and train the ANN. Saved ANN's weights map the phase velocity dispersion curves to values of the S-wave velocity and layers thickness. To estimate the uncertainties, we adapt the Monte-Carlo simulation strategy and project onto the resulting velocity model both frequency-dependent data noise and inverse operator errors, which are evaluated by the prediction of the training data set. The proposed combination of surface waves data processing methods, configured with each other, provides a novel surface waves multi-modal dispersion data inversion and uncertainty quantification approach. We first test our approach on synthetic experiments for various velocity models: a positive velocity gradient, a low-velocity layer and a high-velocity layer. This is done considering uni-modal inversion at first and then compared to the multi-modal inversion. Afterwards, we apply our approach to field data and compare resulting models with the body S-wave processing by the generalized reciprocal method (GRM).

The experiments show high-potential results - using ANN yields the possibility to accurately estimate PPD of restored model parameters without a significant computational effort. The PPD-based comparison demonstrates advantages of a multi-modal inversion over uni-modal inversion. The trained ANN provides reasonable model parameters predictions and related uncertainties in real-time.
Terahertz (THz) plasmonic devises based on periodical corrugated structures are promising for sensing applications in biology and medicine but have not been developed so far because spoof surface plasmons (SSPs) on such structures were studied insufficiently in the THz spectral range. In the paper, the propagation of THz SSPs along one-dimensional subwavelength rectangular plane gratings with a dielectric substance in the grooves was studied and optimal parameters of gratings (period, aspect ratio and groove depth) for sensing of dielectric were found. First grating samples were made and tested using the THz radiation of the Novosibirsk free electron laser.
Results are presented of occasional photographic records of butterflies (Lepidoptera, Papilionoidea) made along with studies on the Odonata fauna in 63 localities of four coastal provinces of SW Cambodia (Koh Kong, Preah Sihanouk, Kampot and Kep) in 2010-2018. In total, 151 identified and 15 provisionally identified species are listed; 39 identified species (Troides helena, Graphium agetes, Prioneris philomone, Abisara echerias, Arhopala abseus, A. aedias, A. aida, A. alitaeus, A. atosia, A. avatha, A. bazaloides, A. elopura, Cigaritis lohita, Sinthusa nasaka, Lampides boeticus, Udara selma, Zizeera karsandra, Danaus affinis, Euploea phaenareta, Parantica agleoides, Cyrestis themire, Euthalia malaccana, E. phemius, Discophora timora, Lethe mekara, Badamia exclamationis, Burara harisa, Odina decorata, Tagiades menaka, Ancistroides nigrita, Gangara lebadea, Halpe zola, Hyrtaotis adrastus, Lotongus calathus, Matapa aria, M. sasivarna, Pirdana hyela, Suastus minutus, Thoressa masoni) and 8 provisionally identified species (Poritia cf. erycinoides, Nacaduba cf. pavana, ?Cephrenes acalle, Erionota cf. torus, Halpe cf. hauxvillei, Notocrypta cf. clavata, Potanthus cf. subochraceus, ?Polytremis lubricans) are for the first time reported for Cambodia. These, as well as some other provisionally identified and unidentified species are illustrated. The only not so expected record is a Sondaic species Arhopala athada.
In most cases modern distributed computer systems (computer clusters and MPP systems) have hierarchical organization and non-uniform communication channels between elementary machines (computer nodes, processors or processor cores). Execution time of parallel programs significantly depends on how they map to computer system (on what elementary machines parallel processes are assigned and what channels for inter-process communications are used). The general problem of mapping a parallel program into a distributed computer system is a well known NP-hard problem and several heuristics have been proposed to approximate its optimal solution.

In this paper an algorithm for mapping parallel programs into hierarchical distributed computer systems based on task graph partitioning is proposed. The software tool for mapping MPI applications into multicore computer clusters is considered.

The quality of this algorithm with the NAS Parallel Benchmarks is evaluated.
The Halomonas sp. isolate SL48-SHIP-3 genome was obtained from metagenomics sequencing of the microbial mat of Salt Lake Number 48 (54.201806N, 78.179194E; Novosibirsk region, Russia). The sequenced and annotated genome is 2,575,909 bp and encodes 2,368 genes.
The authors of this scientific paper examine the current situation in the Russian Federation associated with the pollution of water and the atmospheric resources, with the problem of production and consumption waste accumulation, and draw their attention to the imperfection of statistical information, which does not allow for an objective assessment of the environmental situation. The quality of natural resources is not improving despite the statistical decrease in emissions and discharges of pollutants. They concluded an inconsistency of the economic development in the Russian Federation with the principles of sustainability and the “green” economy. It is necessary to intensify investment activities to protect the natural environment, in order to change the situation. At present, the share of the environmental investments in all national economic capital investments is negligible - less than 1%. The sluggish dynamic of investment processes led to insufficient commissioning of the main environmental funds. Recently, the situation has worsened in connection with the sequestration of the national project “Ecology” due to the pandemic problems. The article is devoted to the analyses of the “green” investment processes in Russia. The author’s definition of “green” investment is given.
We report the first observation of the $$\Xi _{c}(2930)^0$$ charmed-strange baryon with a significance greater than 5 $$\sigma $$ . The $$\Xi _{c}(2930)^0$$ is found in its decay to $$K^- \Lambda _{c}^+$$ in $$B^{-} \rightarrow K^{-} \Lambda _{c}^{+} \bar{\Lambda }_{c}^{-}$$ decays. The measured mass and width are $$[2928.9 \pm 3.0(\mathrm stat.)^{+0.9}_{-12.0}(\mathrm syst.)]$$ MeV/ $$c^{2}$$ and $$[19.5 \pm 8.4(\mathrm stat.) ^{+5.9}_{-7.9}(\mathrm syst.)]$$ MeV, respectively, and the product branching fraction is $$\mathcal{B}(B^{-} \rightarrow \Xi _{c}(2930)^0 \bar{\Lambda }_{c}^{-}) \mathcal{B}(\Xi _{c}(2930)^0 \rightarrow K^- \Lambda _{c}^{+})=[1.73 \pm 0.45(\mathrm stat.) \pm 0.21(\mathrm syst.)]\times 10^{-4}$$ . We also measure $$\mathcal{B}(B^{-} \rightarrow K^{-} \Lambda _{c}^{+} \bar{\Lambda }_{c}^{-}) = [4.80 \pm 0.43(\mathrm stat.) \pm 0.60(\mathrm syst.)] \times 10^{-4}$$ with improved precision, and search for the charmonium-like state Y(4660) and its spin partner, $$Y_{\eta }$$ , in the $$\Lambda _{c}^{+}\bar{\Lambda }_{c}^{-}$$ invariant mass spectrum. No clear signals of the Y(4660) nor its spin partner are observed and the 90% credibility level (C.L.) upper limits on their production rates are determined. These measurements are obtained from a sample of $$(772\pm 11)\times 10^{6} B\bar{B}$$ pairs collected at the $$\Upsilon (4S)$$ resonance by the Belle detector at the KEKB asymmetric energy electron–positron collider.
We propose a novel effective framework for analysis of the shared genetic background for a set of genetically correlated traits using SNP-level GWAS summary statistics.

This framework called SHAHER is based on the construction of a linear combination of traits by maximizing the proportion of its genetic variance explained by the shared genetic factors. SHAHER requires only full GWAS summary statistics and matrices of genetic and phenotypic correlations between traits as inputs. Our framework allows both shared and unshared genetic factors to be to effectively analyzed.

We tested our framework using simulation studies, compared it with previous developments, and assessed its performance using three real datasets: anthropometric traits, psychiatric conditions and lipid concentrations. SHAHER is versatile and applicable to summary statistics from GWASs with arbitrary sample sizes and sample overlaps, allows incorporation of different GWAS models (Cox, linear and logistic) and is computationally fast.
The creation of varieties adapted to changing environmental conditions, resistant to various pathogens, and satisfying various grain purposes is impossible without using the genetic diversity of wheat. One of the ways to expand the genetic diversity of wheat is to introduce new variants of genes from the genetic pool of congeners and wild relatives into the genotypes of existing varieties.

In this study, we used 10 lines from the Arsenal collection created on the genetic basis of the spring variety ‘Rodina’ and the diploid species Aegilops speltoides in the Federal Research Center “Nemchinovka” in 1994. The lines were previously characterized for the presence of translocations and chromosomal rearrangements cytologically and using molecular markers. Technological analyses were performed on grain obtained in Western Siberia and Moscow region. The aim of this study was to establish the possibilities of expanding the phenotypic diversity for technological properties of grain and flour as a result of such hybridization of bread wheat and the diploid cereal Aegilops speltoides.

The variety ‘Rodina’ forms a vitreous grain with a high gluten content in Siberia, but has low physical properties of flour and dough. Five derived lines were found to have significantly higher protein and gluten content in grain. The highest values under both growing conditions were found in lines 73/00i, 82/00i, and 84/00i. Two lines (69/00i and 76/00i) showed a high flour strength and dough elasticity, characterizing the lines as strong and valuable in quality. These lines can be used for baking bread. Line 82/00i inherited from Ae. speltoides a soft-grain endosperm, which indicates the introgression of the Ha-Sp gene, homoeoallelic to the Ha gene of bread wheat, into ‘Rodina’. Flour of this line is suitable for the manufacture of confectionery without the use of technological additives. The lines generally retained their characteristics in different growing conditions. They can be attracted as donors of new alleles of genes that determine the technological properties of grain and resistance to biotic stresses.
c‐ fos gene expression in two types of mouse sarcoma cells of spontaneous origin and in revertants to pseudonormal phenotype has been investigated. In the latter cells the content of c‐ fos mRNA is similar to that in normal fibroblasts.

Activity of transcription factors interacting with the regulatory elements, SRE, DSE and TRE, in the c‐ fos promoter do not correlate with the c‐ fos mRNA concentration. However, experiments with cells transformed with the indicator plasmid, fos ‐CAT, showed that the 600 bp c‐fos promoter region provides the chloramphenicol acetyltransferase activity correlating with c‐ fos mRNA expression in cell revertants to a pseudonormal phenotype.

the 600 bp c‐fos promoter region provides the chloramphenicol acetyltransferase activity correlating with c‐ fos mRNA expression in cell revertants to a pseudonormal phenotype.
The article discusses the issue of the content of the pre-contractual legal relationship and the role of good faith in it.

As a result of the analysis, it is concluded that the content of the pre-contractual legal relationship includes only one pre-contractual obligation – to negotiate in good faith. It should be considered as a duty that includes separate elements – manifestations of the general obligation of the parties to behave in good faith, arising at the pre-contractual stage, or, in other words, requirements for good behavior. These elements include the obligation to inform; the obligation not to interrupt negotiations without giving reasons if the other party relied on the person's intention to conclude a contract; the obligation to keep the information received in confidentiality if the party knows that the information is secret and cannot be used by third parties.

An attempt has been made to prove that the meaning of good faith is not in addition to the pre-contractual obligation, but in its specification.
The article analyzes the situation of the formation of organized philosophical and scientific discourse in the pre-Socratic time, as well as in Alexandria and in the Arab Caliphate. It is shown that in all three cases it is, firstly, poetry that raised the verbal culture to such a level that the possibilities of using language expanded drastically and extreme generalizations became possible. Secondly, poetry performed a reflection upon mythology and formulated the problems that became the starting point of philosophical and scientific research. Poetry also inspired philosophers and scholars to use poetic forms to Express their ideas and improve their language.
A search for the decays $B^0_{s}\rightarrow \mu^+ \mu^- \mu^+ \mu^-$ and $B^0 \rightarrow \mu^+ \mu^- \mu^+ \mu^-$ is performed using data, corresponding to an integrated luminosity of 1.0\ensuremath{\{\,fb}^{-1}}\xspace, collected with the LHCb detector in 2011.

The number of candidates observed is consistent with the expected background and, assuming phase-space models of the decays, limits on the branching fractions are set. In addition, limits are set in the context of a supersymmetric model which allows for the $B^0_{(s)}$ meson to decay into a scalar ($S$) and pseudoscalar particle ($P$), where $S$ and $P$ have masses of 2.5 GeV and 214.3 MeV, respectively, both resonances decay into $\mu^+\mu^-$.

The branching fraction limits for these decays are \{${\ensuremath{\cal B}\xspace}(\ensuremath{B^0_{s}\rightarrow SP}\xspace) < 1.6 \ (1.2) \times 10^{-8}$} and \{${\ensuremath{\cal B}\xspace}(\ensuremath{B^0\rightarrow SP}\xspace)< 6.3 \ (5.1) \times 10^{-9}$} at 95% (90%) confidence level.
The carried out researches with the help of 40Ar/39Ar analysis have shown a coincidence of formation (about 490 million years) of Paleozoic picrite and basalt complexes of the basement of the Western Siberian Plate.

The data on petrochemistry, geochemistry of rare and rare-earth elements, and also on compositions of clinopyroxenes, testifies to formation of picrites of borehole № 11 (Chkalovsky area) as a result of action of intra plate magmatic systems of oceanic islands - OIB. Calculations on the basis of clinopyroxene compositions speak about considerable parameters of crystallization of picrite porphyrite minerals: 1215-1275 °C, 4.5-8 kbar.

As a whole, it is established that considered picrite basalt complexes were formed with the assistance of enriched plume magmatic systems in intra plate conditions of ancient ocean near to its active margin.
Background Russia has one of the highest rates of mortality from cardiovascular disease (CVD). At age 35–69 years, they are eight times higher than in neighbouring Norway. Comparing profiles of blood-based CVD biomarkers between these two populations can help identify reasons for this substantial difference in risk. Methods We compared age-standardised mean levels of CVD biomarkers for men and women aged 40–69 years measured in two cross-sectional population-based studies: Know Your Heart (KYH) (Russia, 2015–2018; n=4046) and the seventh wave of the Tromsø Study (Tromsø 7) (Norway, 2015–2018; n=17 646). A laboratory calibration study was performed to account for inter-laboratory differences. Results Levels of total, low-density lipoprotein-, high-density lipoprotein-cholesterol and triglycerides were comparable in KYH and Tromsø 7 studies. N-terminal pro-b-type natriuretic peptide (NT-proBNP), high﻿-sensitivity cardiac ﻿troponin T (hs-cTnT) and high﻿-sensitivity C-reactive protein (hsCRP) were higher in KYH compared with Tromsø 7 (NT-proBNP was higher by 54.1% (95% CI 41.5% to 67.8%) in men and by 30.8% (95% CI 22.9% to 39.2%) in women; hs-cTnT—by 42.4% (95% CI 36.1% to 49.0%) in men and by 68.1% (95% CI 62.4% to 73.9%) in women; hsCRP—by 33.3% (95% CI 26.1% to 40.8%) in men and by 35.6% (95% CI 29.0% to 42.6%) in women). Exclusion of participants with pre-existing coronary heart disease (279 men and 282 women) had no substantive effect. Conclusions Differences in cholesterol fractions cannot explain the difference in CVD mortality rate between Russia and Norway. A non-ischemic pathway to the cardiac damage reflected by raised NT-proBNP and hs-cTnT is likely to contribute to high CVD mortality in Russia.
Photochemistry of Fe(III) hydroxocomplexes has a great interest because of possibility of hydroxyl radical formation at the primary photochemical step. This mechanism is based mainly on the analysis of the final products of photochemical reactions between light‐excited Fe(III) complexes and organic compounds. However, realization of an alternative mechanism of photolysis, based on the intermolecular electron transfer from organic molecules located in the second coordination sphere to the light‐excited complex could take place.

To distinguish these mechanisms, the experiments on the nanosecond laser flash photolysis of Fe(OH) aq 2+ in water solutions (pH 3) with organic additives; namely nitrobenzene, N,N‐dimethylformamide, and phenol have been performed. And the formation of the organic radicals Ph(•OH)NO 2 , HCON(CH 2 •)(CH 3 ), and Ph(OH) 2 •, was observed, respectively. The rate constants of the formation and decay of the radicals coincide with those found in literature.

The results support the formation of the hydroxyl radical upon the photolysis of Fe(OH) aq 2+.