Hengzongshu/ArticleAgent huggingface dataset:
Results obtained through the analysis of water-gas equilibria in formation waters are shown to form the basis of the technology aimed at search for hydrocarbon pools. A direct dependence of a decrease in total gas saturation, the concentrations of methane homologues and water composition on the distance from water-oil contacts was established. A connection between hydrogeochemical anomalies and hydrocarbon pools was also detected It was revealed from the nature of the equilibria that hydrocarbon pools in the Paleozoic and Mesozoic sediments of the southern parts of the Ob-Irtysh interfluve act as a conservative element of the lithosphere. Water-gas equilibria modeling revealed that the geochemical regime dominating at the major part of the territory under study is favourable for the formation and conservation of hydrocarbon pools, except for the marginal zones. Computer modeling of physicochemical equilibria and evasion-invasion processes in water-gas systems allowed us to establish the degree of groundwater saturation with gases and the nature of diffusion redistribution of gases at the boundary between hydrocarbon deposit and formation water. All waters with total gas saturation of 2.0 l/l become ultimately saturated with gases (Kg = 2.0), which means that theoretical prerequisites for the formation of hydrocarbon deposits arise. Calculations allowed us to reveal more than 30 promising objects with the high probability of detection of hydrocarbon deposits at the Bergul, Vitin, Chekovsky and other areas.
The special and temporal distribution of several posttranslational histone modifications (H3K4me2, H3K4me3, H3K9me2, H3K27me2, H3K9ac, H3K14ac, H3K18ac, H3K27ac, H3S10ph, H3S28ph, H3T3ph, H3K4me1-H3T3ph, H3K4me3/H3T3ph H3T11ph, H2AT121ph, and H2A.XS139ph) has been analysed during microsporogenesis of tobacco.

Homogeneous distribution of the euchromatin marks H3K4me2 and H3K4me3 throughout the entire chromatin of amphidiploid Nicotiana tabacum suggests that both subgenomes were transcriptionally active. Localization of hyperacetylated clusters of H3K18 and H3K27 close to nucleoli suggests that both modifications were possibly involved in transcription of the 45S rDNA. A subset of chromosomes showed clusters of hypermethylated H3K9me2 and H3K27me2 regions.

The cell-cycle dependent phosphorylation of histone H3 during meiosis revealed a high conservation compared to other plant species. In addition to meiotic prophase I, we observed phospho-H2A.X signals during the second stage of meiosis in N. tabacum.
Results are presented of occasional photographic records of butterflies (Lepidoptera, Papilionoidea) made along with studies on the Odonata fauna in 63 localities of four coastal provinces of SW Cambodia (Koh Kong, Preah Sihanouk, Kampot and Kep) in 2010-2018.

In total, 151 identified and 15 provisionally identified species are listed; 39 identified species and 8 provisionally identified species are for the first time reported for Cambodia. These, as well as some other provisionally identified and unidentified species are illustrated.

The only not so expected record is a Sondaic species Arhopala athada.
The word survive has two meanings: one, more heroic and romantic, refers to the idea of being able to succeed in life better than the others; on the other hand, another concept that can be associated to the word survive is more related to the ability to make a living out of scarce resources. Both meanings can be applied to academic life nowadays.

This communication will explore the obstacles and pitfalls that can be encountered during the early stages of an academic career. Some examples will be discussed of different situations found in different countries, and gender issues will be analyzed.

The importance of networking will be highlighted.
The tumor‐suppressor gene encoding the cyclic AMP‐dependent protein kinase A type I‐α regulatory subunit PRKAR1A has been mapped to chromosome 17 (17q22–24) and is mutated in Carney complex, a familial neoplasia syndrome that is associated with thyroid tumors. Other genes implicated in cyclic nucleotide‐dependent signaling have been investigated in thyroid tumorigenesis. We studied protein kinase A (PKA) activity in noninherited follicular thyroid adenomas and follicular, papillary, and undifferentiated (anaplastic) thyroid carcinomas. We then examined these and additional thyroid tumors for losses of the 17q22–24 PRKAR1A region, mutations of the PRKAR1A gene, and expression of its peptide product. Total PKA activity was markedly increased in carcinomas over that in adenomas, whereas the ratio of free vs. total PKA activity was decreased in cancer. Consistent with these findings, the 17q22–24 region was frequently lost in cancer but not in benign adenomas. A novel inactivating mutation of the PRKAR1A gene (leading to premature termination of the predicted protein) was found in an aggressive thyroid cancer. The tumor with PRKAR1A gene mutation, as well as the tumors with 17q allelic losses, showed decreased PRKAR1A expression by immunostaining. We conclude that PRKAR1A, the most abundant regulatory subunit of protein kinase A and a principal cyclic AMP‐signaling modulator, acts as a tumor‐suppressor gene in sporadic thyroid cancer. Published 2002 Wiley‐Liss, Inc.
To study the diagnostic significance of genetic testing in patients with dilated cardiomyopathy (DCM), identify predictors of life-threatening ventricular tachyarrhythmias (VTAs) and assess adverse clinical outcomes in different genetic groups.

The study included 126 unrelated patients with verified DCM as follows: 70 (55,6%) probands with criteria for familial DCM and 56 (44,4%) individuals with a probable hereditary component. All patients (age, 43,1±11,3 years; men, 92 (73%); left ventricular ejection fraction, 30,6±8,43%; left ventricular enddiastolic diameter, 68,3±8,36 mm; follow-up period — median, 49 months) receive a complex of diagnostic investigations, including genetic screening using nextgeneration sequencing, followed by verification of variants by the Sanger method.

The phenotypes of DCM with TTNtv did not significantly differ in the incidence of VTAs and adverse outcomes compared with the gene-negative group and other genotypes (with the exception of LMNA). The contribution of the associations of LMNA mutations with VTAs on prognosis was confirmed, which shows the important role of LMNA genotype diagnosis for SCD risk stratification in patients with DCM.
The paper deals with molecular dynamics simulation of fluid flow characteristics in nanochannels.

A new MD algorithm is developed to simulate plane flow with a pressure drop along the channel. Fluids of hard spheres and Lennard-Jones molecules are considered. Emphasis is on the study of the dependence of the hydraulic flow resistance on the fluid structure. An analysis was made of (i) the density distribution across and along the channel; (ii) radial distribution function of the fluid near the channel wall and in bulk; (iii) influence of the interaction law of the molecules with the wall;

the dependence of the flow resistance coefficient on the Reynolds and Knudsen numbers.
We for the first time demonstrate that nanoscale structural anomalies, recently discovered in ionic liquids, are more general and ubiquitous phenomena, occurring also in various organic glass-formers with alkyl chains of the proper length.
The Wiener index, W , is the sum of distances between all pairs of vertices in a graph G. The quadratic line graph is defined as L(L(G)), where L(G) is the line graph of G. A generalized star S is a tree consisting of ∆ ≥ 3 paths with the unique common endvertex. A relation between the Wiener index of S and of its quadratic graph is presented. It is shown that generalized stars having the property W (S) = W (L(L(S)) exist only for 4 ≤ ∆ ≤ 6. Infinite families of generalized stars with this property are constructed.
In this study, we assembled a complete mitochondrial genome of the Acanthobdella peledina sample from the Pitea River, Sweden. Thirty-six genes of the mitogenome sequence were identified, including 13 protein-coding genes (PCGs), 2 ribosomal genes (12S and 16S), 21 transport RNA genes, and 1 control region.

The complete mitogenome is 14,640 bp long and A + T biased (70.59%).
Although the wheat A genomes have been intensively studied over past decades, many questions concerning the mechanisms of their divergence and evolution still remain unsolved. In the present study we performed comparative analysis of the A genome chromosomes in diploid (Triticum urartu Tumanian ex Gandilyan, 1972, Triticum boeoticum Boissier, 1874 and Triticum monococcum Linnaeus, 1753) and polyploid wheat species representing two evolutionary lineages, Timopheevi (Triticum timopheevii (Zhukovsky) Zhukovsky, 1934 and Triticum zhukovskyi Menabde & Ericzjan, 1960) and Emmer (Triticum dicoccoides (Körnicke ex Ascherson & Graebner) Schweinfurth, 1908, Triticum durum Desfontaines, 1798, and Triticum aestivum Linnaeus, 1753) using a new cytogenetic marker - the pTm30 probe cloned from Triticum monococcum genome and containing (GAA)56 microsatellite sequence. Up to four pTm30 sites located on 1AS, 5AS, 2AS, and 4AL chromosomes have been revealed in the wild diploid species, although most accessions contained one-two (GAA)n sites. The domesticated diploid species Triticum monococcum differs from the wild diploid species by almost complete lack of polymorphism in the distribution of (GAA)n site. Only one (GAA)n site in the 4AL chromosome has been found in Triticum monococcum. Among three wild emmer (Triticum dicoccoides) accessions we detected 4 conserved and 9 polymorphic (GAA)n sites in the A genome. The (GAA)n loci on chromosomes 2AS, 4AL, and 5AL found in of Triticum dicoccoides were retained in Triticum durum and Triticum aestivum. In species of the Timopheevi lineage, the only one, large (GAA)n site has been detected in the short arm of 6A(t) chromosome. (GAA)n site observed in Triticum monococcum are undetectable in the A(b) genome of Triticum zhukovskyi, this site could be eliminated over the course of amphiploidization, while the species was established. We also demonstrated that changes in the distribution of (GAA)n sequence on the A-genome chromosomes of diploid and polyploid wheats are associated with chromosomal rearrangements/ modifications, involving mainly the NOR (nucleolus organizer region)-bearing chromosomes, that took place during the evolution of wild and domesticated species.
This paper discusses the trends in the experimental studies of molecular organic solids at high pressures by diffraction techniques.

Crystallization of liquids, crystallization from solutions and solid-state transformations are considered.

Special attention is paid to the high-pressure studies of pharmaceuticals and of biomimetics.
The catalytic steam cracking of vacuum residue (VR) in a slurry-type reactor at a temperature of 425-450 °C and 2 MPa in the presence of a Mo-based dispersed catalyst was carried out for the first time.The catalyst was introduced into the feedstock through a reverse emulsion, which was previously prepared from VR and an aqueous solution of the Mo-based precursor salt, followed by decomposition and formation of a dispersion of catalyst particles in the VR.In the case of non-catalytic steam cracking, it was found that the use of water leads to a reduction in coke formation and, correspondingly, an increase in the yield of the target liquid products (semisynthetic oil), while reducing the sulfur content, in comparison with thermal cracking.The results of the study also showed that the use of Mo-based dispersed catalyst increases the depth of interaction between water and VR, with an increase in the H:C ratio and a reduction in sulfur content in liquid products (semisynthetic oil).
Obesity and diabetes mellitus are known to lead to the development of metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). The mechanisms of programmed cell death are actively involved in maintaining cellular homeostasis along development of NAFLD. Proteins of the BCL-2 family are key regulators of physiological and pathological apoptosis.

Homozygous males of BKS.Cg-Dock7 m Lepr db /+/+/J mice ( db/db mice) are characterized by progressive obesity and the development of type 2 diabetes mellitus (DM2) with severe hyperglycemia at 4–8 weeks and organ lesions at 8–10 weeks of age. The aim of this research was to study the expression of molecular cell regulators of apoptosis in liver cells of db/db mice males at different stages of obesity and diabetes development (at the age of 10 and 18 weeks). Immunohistochemical analysis (using the indirect avidin-biotin peroxidase method) and morphometric evaluation of the expression of the antiapoptotic protein Bcl-2 and the proapoptotic protein Bad in liver cells of studied animals at different stages of obesity and DM2 were carried out.

An excess of the value of the Bcl-2 protein staining area over the Bad protein staining area was revealed in the liver of 10-week-old animals. The Bcl-2/Bad expression area ratio in 10-week-old animals was twice as high as in 18-week-old animals, which indicates the presence of conditions for blocking apoptosis in the liver of younger db/db mice. At the 18th week of life, db/db mice displayed an almost threefold increase in the expression area of the Bad protein against the background of an unchanged expression of the Bcl-2 protein. The decrease in the Bcl-2/Bad staining area ratio in 18-week-old animals was due to the increase in the Bad expression area, which indicates the absence of antiapoptotic cell protection and creates conditions for activation of the mitochondrial pathway of apoptosis in the liver of male db/db mice with pronounced signs of obesity and DM2.
The subject of this paper is the stochastic molecular modelling of the transport coefficients for rarefied gases and gas nanosuspensions.The proposed method is an alternative one to the molecular dynamics method.However, unlike the latter, the phase trajectories of the molecular system are simulated stochastically.Adequate integral characteristics of the studied system are obtained by averaging the calculated data over independent phase trajectories.The efficiency of the proposed algorithm is demonstrated by calculation of the diffusion and viscosity coefficients of several noble and polyatomic gases and rarefied gas nanosuspensions.The modeling accuracy increases when a greater number of molecules and phase trajectories are employed.
using a multivariate analysis method to access ~90% of the $B\rightarrow X_{u}\ell\nu$ phase space. This approach dramatically reduces the theoretical uncertainties from the $b$-quark mass and nonperturbative QCD compared to all previous inclusive measurements.

We present the partial branching fraction for inclusive charmless semileptonic $B$ decays and the corresponding value of the Cabibbo-Kobayashi-Maskawa matrix element $|{V}_{ub}|$, using a multivariate analysis method. The results are based on a sample of $657\times 10^{6}$ $B\overline{B}$ pairs collected with the Belle detector.

We find that $\Delta\mathcal{B}(B\rightarrow X_{u}\ell\nu;{p}_{\ell}^{*B}>1.0\ \mathrm{GeV}/c)=1.963\times (1\pm 0.088_{\mathrm{stat}}\pm 0.081_{\mathrm{syst}})\times 10^{-3}$. Corresponding values of $|{V}_{ub}|$ are extracted using several theoretical calculations.
The article analyzes the situation of the formation of organized philosophical and scientific discourse in the pre-Socratic time, as well as in Alexandria and in the Arab Caliphate.

It is shown that in all three cases it is, firstly, poetry that raised the verbal culture to such a level that the possibilities of using language expanded drastically and extreme generalizations became possible. Secondly, poetry performed a reflection upon mythology and formulated the problems that became the starting point of philosophical and scientific research.

Poetry also inspired philosophers and scholars to use poetic forms to Express their ideas and improve their language.
Каменная технология среднего этапа верхнего палеолита Северной Монголии (культурный горизонт 2 стоянки Толбор-21
The review considers quarantine species and nematode pathotypes potentially dangerous for domestic potato production. Potatoes are affected by more than 30 types of parasitic nematodes, but the review focuses on the most harmful representatives of genera that cause great damage to potato production: Globodera, Ditylenchus, Nacob bus and Meloidogyne. Phytopathological and molecular methods of identification of species and pathotypes and the main achievements in studying the population variability of parasitic potato nematodes were analyzed. It was shown that due to the peculiarities of the life cycle of nematodes and lability of their genomes, the genetic variability of these organisms is very high, which creates a threat of forming new pathogenic genotypes of the parasites. The information about the intra- and interpopulation variability of nematodes is important for studying the ways of introduction and distribution of separate species, as well as for searching for the correlations of molecular markers with the pathotype. Phylogenetic studies based on modern data on genetic variability of populations have allowed to reveal species complexes in Globodera pallida (Stone) Behrens and Nacobbus aberrans (Thorne) Thorne & Allen (sensu lato), including cryptic species. The main components of successful protection preventing a wide distribution of parasitic nematodes are quarantine measures, agricultural techniques, biological methods of protection and cultivation of resistant cultivars. Special attention in the review is paid to the breeding of potato cultivars with durable resistance to various nematode pathotypes, because the cultivation of such varieties is the most ecologically safe and economically advantageous way to prevent epiphytoties. Currently, significant progress has been made in the genetic protection of potato cultivars, especially against cyst-forming nematodes. The review provides data on sources of potato resistance to parasitic nematodes identified in collections of wild and cultivated species. Data on identified R-gens and QTL of resistance that have been introduced into breeding varieties using different methods and approaches are analyzed. The literature data on the study of structural and functional organization of genes for resistance to potato cyst nematodes are given. The results of molecular research on revealing the polymorphisms of loci involved in the control of resistance to cyst and gall nematodes, the development of molecular markers of certain genes and their use in marker-assisted selection for developing of new resistant cultivars, including those with group resistance, are considered.
Eukaryotic genomes encode thousands of non-coding RNAs (ncRNAs), which play crucial roles in transcriptional and post-transcriptional regulation of gene expression. Accumulating evidence indicates that ncRNAs, especially microRNAs (miRNAs) and long ncRNAs (lncRNAs), have emerged as key regulatory molecules in plant stress responses.

In this review, we have summarized the current progress on the understanding of plant miRNA and lncRNA identification, characteristics, bioinformatics tools, and resources,

and provided examples of mechanisms of miRNA- and lncRNA-mediated plant stress tolerance.
By a graph we mean a finite connected multigraph without bridges. The genus of a graph is the dimension of its homology group. Two graphs are isospectral is they share the same Laplacian spectrum.

We prove that two genus two graphs are isospectral if and only if they are isomorphic. Also, we present two bridgeless genus three graphs that are not isomorphic.

The paper is motivated by the following open problem posed by Peter Buser: are isospectral Riemann surfaces of genus two isometric?
This process has much in common with the widely discussed Mueller-Navelet jet production and can also be used to access the dynamics of hard proton-parton interactions in the Regge limit. For both processes large contributions enhanced by logarithms of energy can be resummed in perturbation theory within the Balitsky-Fadin-Kuraev-Lipatov (BFKL) formalism with next-to-leading logarithmic accuracy.

We propose to study at the Large Hadron Collider (LHC) the inclusive production of a pair of hadrons (a ``dihadron'' system) in a kinematics where two detected hadrons with high transverse momenta are separated by a large interval of rapidity.

The experimental study of dihadron production would provide an additional clear channel to test the BFKL dynamics. We present here the first theoretical predictions for cross sections and azimuthal angle correlations of the dihadrons produced with LHC kinematics.
West Siberia is a large region in North Eurasia, which harbours multiple climatic zones, landscape types and biomes. Its amphibian fauna is characterised by a combination of European and Asian species. For many species, this region is the place where the limits of their global ranges are located ( Rana temporaria , R. amurensis , Bufotes sitibundus ). West Siberia also has at least two non-native amphibian species ( Pelophylax ridibundus , Bufotes viridis ). The exact ranges and patterns of distribution of the West Siberian amphibian species are poorly studied. The mapping of species ranges is important for the development of conservation measures and monitoring of invasive species is required to investigate their impacts on the natural ecosystems. This work presents the most complete biogeographic and occurrence records database of the amphibians of West Siberia. To assemble the database, we digitised data from 190 published works, obtained data from major museum collections and from the data bank on the abundance and distribution of animals «Zoomonitor» by the Zoomonitoring laboratory of the Institute of Systematics and Ecology of Animals, Siberian Branch of Russian Academy of Sciences. The database also includes original and partly unpublished data collected by the authors from 1975 to 2021, as well as quality-assessed citizen science data from the iNaturalist portal. In total, the database contains 2530 records for 11 species of amphibians, including the locality data, the observation date (when known) and the source of the observation (at least one of the following: literature reference, museum sample ID, observer’s name, iNaturalist link).
We present a study of the branching fraction of the decay B^0->rho0rho0 and the fraction of longitudinally polarized rho0 mesons in this decay.

The results are obtained from the final data sample containing 772 million BBbar pairs collected at the Y(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider.

We find 166 +- 59 B^0 -> rho0 rho0 events (including systematic uncertainties), corresponding to a branching fraction of B(B^0->rho0rho0) = (1.02 +- 0.30 (stat) +- 0.15 (syst)) x 10^{-6} with a significance of 3.4 standard deviations and a longitudinal polarization fraction fL = 0.21^{+0.18}_{-0.22} (stat) +- 0.15 (syst). We use the longitudinal polarization fraction to determine the Cabibbo-Kobayashi-Maskawa matrix angle phi_2 = (84.9 +- 13.5) degrees through an isospin analysis in the B->rhorho system. We furthermore find 149 +- 49 B^0->f0rho0 events, corresponding to B(B^0->f0rho0) x B(f0->pi+pi-) = (0.78 +- 0.22 (stat) +- 0.11 (syst)) x 10^{-6}, with a significance of 3.1 standard deviations. We find no other significant contribution with the same final state, and set upper limits at 90% confidence level on the (product) branching fractions, B(B^0->pi+pi-pi+pi-)<11.2 x 10^{-6}, B(B^0->rho0pi+pi-)<12.0 x 10^{-6}, B(B^0->f0pi+pi-) x B(f0->pi+pi-) <3.0 x 10^{-6} and B(B^0->f0f0) x B(f0->pi+pi-)^{2} < 0.2 x 10^{-6}.