Hengzongshu/ArticleAgent huggingface dataset:
The Italian locust is a common species and one of the most important pest in the steppes, semi-deserts, and deserts of Central and Southwestern Asia and also in the Mediterranean Region.

The aim of this paper is to discuss some problems arising from studies of eco-geographical distribution and long-term dynamics of this species, especially in the southern part of West Siberia, and their consequences for management of pest species and rare forms. Peculiarities of the Italian locust populations’ distribution and long-term dynamics are discussed for the north-eastern part of the species range (south-eastern West Siberian Plain, North-East and, partly, East Kazakhstan). Notable differences between local populations are revealed. Some issues arising from results of insecticide experimental treatments (mainly effectiveness of barrier applications with different compounds in variable environment) and ecological association between the Italian locust and rare Orthoptera are also discussed.

Some suggestions as to requirements for improved monitoring, supervision, control, and forecasting of the Italian locust populations’ distribution and dynamics are also provided.
An extension of a finite volume scheme for three-dimensional Maxwell’s equations with discontinuous dielectric permittivity on tetrahedral meshes is discussed. The scheme is second order accurate in time and space for regions with linear and curvilinear discontinuities. It was tested on problems with linear and curvilinear discontinuity configurations. The test results support the second order accuracy of the proposed scheme.
The development of active and stable photocatalysts for the degradation of volatile organic compounds under visible light is important for efficient light utilization and environmental protection. Titanium dioxide doped with nitrogen is known to have a high activity but it exhibits a relatively low stability due to a gradual degradation of nitrogen species under highly powerful radiation.

In this paper, we show that the combination of N-doped TiO
Neurotrophic factors, as well as their receptors are key players in the formation and development of the central nervous system. Like the sculptor’s incisor, they form the neural networks and circuits of the future organism. The neurotrophic growth factor receptor p75ngfr interacts with sortilin, serves as a receptor for proform of neurotrophic factors and exhibits a proapoptotic effect in developing neurons—dorsal root ganglia neurons and brainstem norepinephrine neurons. p75ngfr is highly expressed in Locus Coeruleus norepinephrine neurons. Therefore, an important task for developing further methods of CNS gene therapy is the development of tools and molecular methods for suppressing p75ngfr expression in norepinephrine neurons. For this purpose, we’ve developed improved dCas9 vectors with Suntag system to suppress gene expression and enhance methylation of CpG islands. We used 10 times repetitive GCN peptide that were fused to dCas9. Single chain antibody against GCN peptide was fused to KRAB repressor or Dnmt3a catalytic domain. Expression specificity was achieved by using a promoter consisting of 8 repeated phox2a/2b binding sites. In this work, we’ve tested a set of guide RNAs targeting p75ngfr cpg island in the promoter. Usage of Suntag system led us to the conclusion that topological orientation and length of the final complex could influence on p75ngfr antisense transcript expression, and that sequence was established in the rat P3 brainstem.
The compared study of the properties of liquid-phase and electric explosion alumina nanoparticles was made.

The X-ray diffraction analysis demonstrated that these nanoparticles remain in amorphous and semi-amorphous states. The complete structural information of Al 2 O 3 nanoparticles was obtained as a result of the full-profile refinement of their model phase parameters. The parameters of the unit cells, spatial distribution of atoms, and occupancy of nodes were also determined.The data of IR spectra of surface OH groups and adsorbed CO revealed that the surface imperfection of an electric explosive sample is lower than that obtained using the liquid-phase method. Using photoluminescent spectroscopy, impurities of Cr 3+ , Mn 4+ and Ti 3+ in the octahedral oxygen coordination and Fe 3+ in the tetrahedral oxygen coordination were detected. Using UV-Vis DR spectroscopy, it was found that the liquid-phase sample was amorphous, and the electric explosive sample was well crystallized and most probably consisted of 2D and 3D nanostructures.

It was observed that the concentration of these impurities was significantly higher in the electric explosion sample.
A contactless two-beam modulated photoemission technique for measuring the photovoltage on the surface of highly doped semiconductors is proposed and verified for the p + -GaAs surface with adsorbed Cs. The surface photovoltage evolution under the Cs deposition on the highly doped p + -GaAs surface is compared with that observed on Cs/UP + -structures by the photoreflectance spectroscopy method. The pump intensity dependence of the photovoltage is measured. This allows us to determine the absolute photovoltage values.
We report results on studies of the e+e- annihilation into three-body Y(nS)pi+pi- (n=1,2,3) final states including measurements of cross sections and the full amplitude analysis.

The results are obtained with a $121.4 1/fb data sample collected with the Belle detector at the KEKB asymmetric-energy e+e- collider.

The cross sections measured at sqrt(s)=10.865 GeV and corrected for the initial state radiation are sigma(e+e-=>Y(1S)pi+pi-)=(2.27+-0.12+-0.14) pb, sigma(e+e-=>Y(2S)pi+pi-)=(4.07+-0.16+-0.45) pb, and sigma(e+e-=>Y(3S)pi+pi-)=(1.46+-0.09+-0.16) pb. Amplitude analysis of the three-body Y(nS)pi+pi- final states strongly favors I^G(J^P)=1^+(1^+) quantum-number assignments for the two bottomonium-like Zb+- states, recently observed in the Y(nS)pi+- and hb(mP)pi+- (m=1,2) decay channels.
This paper deals with the evaluation of oil-generation potential derived from the geochemical data on deep-buried Jurassic sedimentary rocks of the Nadym-Taz interfluve being part of the West Siberian petroleum basin (PB). The study provides analysis of samples from ultra-deep and deep wells that penetrated the Mesozoic-Cenozoic sedimentary cover in the north of the central part of PB (En-Yakhinsky, Evo-Yakhinsky, Yarudeysky, Tyumensky areas, etc.).

The research focuses on the insoluble organic matter (OM) from Upper, Middle and Lower Jurassic sediments (54 samples). A comprehensive study of the kerogen by elemental, isotope analyses and pyrolysis Rock-Eval allowed obtaining the data critical for determining the genetic type of OM, its thermal maturity and residual petroleum generating potential. Using the Surfer and Corel Draw software, schematic maps and diagrams of variations in the most informative (i.e. area-specific and depth-dependent) geochemical parameters of the kerogen on the studied area and also down the section (from the Upper to the Lower Jurassic) were constructed and analyzed.

The obtained geochemical data indicate that in the Jurassic sediments of the Nadym-Tazovsky interfluve, the highest OM generation potential is found in the Bazhenov horizon, as well as in individual members of the Malyshevsky, Leontievsky, Sharapovsky and Kiterbyutsky horizons. Based upon the level of OM maturity in the Upper and Middle Jurassic sediments, deposits of mainly oil and fat gases could be preserved, and in the Lower Jurassic – deposits of fat and dry gases.
Nonreciprocal transport, where the left-to-right-flowing current differs from the right-to-left-flowing one, is an unexpected phenomenon in bulk crystals. BiTeBr is a noncentrosymmetric material, with a giant Rashba spin-orbit coupling which presents this unusual effect when placed in an in-plane magnetic field. It has been shown that this effect depends strongly on the carrier density; however, in situ tuning has not yet been demonstrated.

We developed a method where thin BiTeBr flakes are gate tuned via ionic-liquid gating through a thin protective hexagonal boron nitride layer.

Tuning the carrier density allows a more than $400%$ variation of the nonreciprocal response in our sample. Our study demonstrates how a few-atomic-layer-thick van der Waals protection layer allows ionic gating of chemically sensitive, exotic nanocrystals.
We present the results of development of an optical frequency standard based on Yb:YAG laser with second harmonic at 515 nm. The laser frequency is locked to the saturated-absorption resonance in a gas cell filled with molecular iodine.

Final instability of the standard is 1.3×10–15 at 104 s.
Effects of a subanesthetic dose of ketamine and acute stress on the major (p75, Trkb, Trkc) and novel (Sorcs1, Sorcs2, Sorcs3) neurotrophin receptors and Bdnf gene expression in rats were examined.Adult male Wistar rats were treated with ketamine (15 mg/kg) or saline and half of each group was subjected to tail suspension test for 6 minutes, which was interpreted as an acute mild stressor.After an hour the total RNA was isolated from prefrontal cortex, midbrain and brainstem regions of each animal and mRNA expressions were analysed by real-time RT-PCR.The results showed different significant interactions between factors which were strongly dependent on the structure of the brain.Both subanesthetic doses of ketamine and acute mild stress caused changes in neurotrophin receptors and Bdnf gene expression in examined brain areas associated with depression.The obtained results allow to surmise that BDNF, SORCS1, SORCS3 and p75 receptors are involved in the ketamine-induced neuroplasticity and antidepressant activity.
Geospatial monitoring of leaves variability has been performed for Platanus orientalis L. (Platanaceae) in Hissar Valley of Tajikistan. 17 local populations were clustered in four territorial groups and investigated by 11 morphometric variables and four indices. Six levels of variability were taken in the classification of S.A. Mamaev.

All tested parameters were ranked due to the total score of variability levels. It was established, that indicators which have the combination of high, increased, and medium levels of variability, can be recommended for the purpose of geospatial monitoring. In the studied set of variables are two such ones: (1) the ratio of the length of leaf blade to the lengh of petiole, and (2) the petiole lengh.

These two indicators reliably respond to point sources of industrial environmental pollution (Aluminum and Cement factories). Six indicators with domination of the middle level of variability, are of diagnostic value to differ loci inside territorial groups of populations. The results of the experiment confirmed, that set of variability levels for 8 of 15 studied parameters has diagnostic matter for geospatial monitoring of environment conditions in Hissar Valley of Tajikistan.
The structure of supersonic underexpanded room temperature air microjets is experimentaly studied. Microjets escaping from the nozzles with characteristic heights of 22.3 and 83.3 μm and widths of 2410 and 3900 μm respactacly with the Reynolds numbers of 640 and 2390. At these Reynolds numbers hot-wire anemometer measurements of mass flow pulsations are performed. It is shown that low value of the mass flow pulsations are corresponding with the high supersonic core length.
Hyperammonemia is an acute or chronic intoxication with ammonia and ammonium associated with elevated ammonia levels in serum due to either its increased production and/or decreased detoxification. Hyperammonemia can result from a variety of causes and clinically presents with unspecific signs and symptoms, including asthenia, encephalopathy, liver steatosis or fibrosis, and sarcopenia. With impaired liver function, hyperammonemia most frequently manifests in (micro)encephalopathy.

An express method of photometric assay is informative enough to determine the ammonia levels. The following hyperammonemia classification is proposed: a) by ammonia levels (normal level: ≤ 60 μmol/L; mild (Grade 1): ≤ 100 μmol/L; moderate (Grade 2): ≤ 200 μmol/L; and severe (Grade 3): > 200 μmol/L); b) by etiopathogenesis (hereditary (congenital), functional (physiological), acquired (hepatic, extrahepatic, mixed)); c) by clinical presentation (transient, recurrent or persistent, constant (stable, without treatment), covert).

Treatment for hyperammonemia is aimed at treating the primary disease and includes a diet that is restricted in animal protein but contains sufficient vegetable protein, limited physical activities, and use of intestinal non-absorbable antibiotics (rifaximin- alpha) as well as pre- and probiotics. L-ornithine- L-aspartate (LOLA) is a baseline therapeutic product administered in a number of scenarios to correct the level of hyperammonemia.
The evolution of three-dimensional waves into thermocapillary-wave structures, rivulets deflection, heat transfer enhancement and rupture vertically falling water film at heating were studied. Characteristics of the film flow were determined experimentally using simultaneous measurements of thickness and temperature fields on the falling heated liquid film surface (LIF and IR scanner). The amplitudes and velocities of waves, amplitudes of rivulet deflection, temperature fluctuations on the film surface, frequency spectra and pulsation energies were determined. Several different types of instability were registered on the surface of the heated fluid film: 3D hydrodynamic and thermocapillary A, B and C instabilities. The thermocapillary structures of type A arise in the residual layer behind the front of the wave, leading to an increase in the amplitude of the waves and rivulets deflection amplitudes. It is shown that the heat flux of rupture increases and intensity of heat transfer enhances due to an increase in the surface waves and rivulet deflection amplitudes.
The Arbarastakh ultramafic carbonatite complex is located in the southwestern part of the Siberian Craton and contains ore-bearing carbonatites and phoscorites with Zr-Nb-REE mineralization. Based on the modal composition, textural features, and chemical compositions of minerals, the phoscorites from Arbarastakh can be subdivided into two groups: FOS 1 and FOS 2. FOS 1 contains the primary minerals olivine, magnetite with isomorphic Ti impurities, phlogopite replaced by tetraferriphlogopite along the rims, and apatite poorly enriched in REE. Baddeleyite predominates among the accessory minerals in FOS 1. Zirconolite enriched with REE and Nb and pyrochlore are found in smaller quantities. FOS 2 has a similar mineral composition but contains much less olivine, magnetite is enriched in Mg, and the phlogopite is enriched in Ba and Al. Of the accessory minerals, pyrochlore predominates and is enriched in Ta, Th, and U; baddeleyite is subordinate and enriched in Nb. Chemical and textural differences suggest that the phoscorites were formed by the sequential introduction of different portions of the melt. The melt that formed the FOS 1 was enriched in Zr and REE relative to the FOS 2 melt; the melt that formed the FOS 2 was enriched in Al, Ba, Nb, Ta, Th, U, and, to a lesser extent, Sr.
Background Cardiovascular event rates increase with age in all populations. This is thought to be the result of multiple underlying molecular and cellular processes that lead to cumulative vascular damage. Apart from arterial stiffness based on pulse wave velocity there are few other non-invasive measures of this process of vascular aging.

We use data collected in two cross-sectional studies of adults aged 40-69 years in Norway and Russia to test the hypothesis that mean levels of δ-age, derived from a deep-learning model trained on a US population, correspond to the known large differences in cardiovascular mortality between the two countries.

Findings Substantial differences were found in mean δ-age between populations: Russia-USA (+5·2 years; 0·7, 10 IQR) and Norway-USA (-2·6 years; -7, 2 IQR). These differences were only marginally explained when accounting for differences in established cardiovascular disease risk factors. Interpretation δ-age may be an important biomarker of fundamental differences in cardiovascular disease risk between populations as well as between individuals.
The obtained results were compared with the flow structure in the closed cylindrical container.

The structure of confined vortex flow generated by a rotating lid in a closed container with polygonal cross-section geometry (eight, six and five angles) has been investigated numerically for different height/radius aspect ratios h from 3.0 to 4.5 and for Reynold numbers ranging from 1500 to 3000. The critical Reynolds numbers at which the flow becomes unsteady were determined numerically by STAR-CCM+ computational fluid dynamics software for pentagonal and hexagonal cross-section configurations.

The boundary of a nonstationarity in polygonal containers is found to shift to the region of smaller aspect ratio and smaller Reynolds numbers with a decrease in the number of angles in the cross-section of the container relative to the boundary in a cylindrical container. It is additionally established that the structure of the flow in the near-axis region remains similar to the vortex structure in the cylinder, therefore the shape of the container does not influence the near-axis region.
Systemic lupus erythematosus (SLE) is an inflammatory disease. The sera of SLE patients contain antibodies-abzymes hydrolyzing myelin basic protein (MBP), DNA, nucleotides, and oligosaccharides. The blood of SLE patients contains an increased amount of some specific miRNAs.

Using affinity chromatography of the serum proteins of SLE patients and healthy donors on protein G-Sepharose and following FPLC gel filtration, electrophoretically homogeneous IgG preparations containing no impurities of canonical RNases were obtained. These preparations were used to analyze their activity in the hydrolysis of eight miRNAs.

It was shown that SLE IgGs hydrolyze very efficiently four neuroregulatory miRNAs (miR-219-2-3p, miR-137, miR-219a-5p, and miR-9-5p) and four immunoregulatory miRNAs (miR-326, miR-21-3p, miR-155-5p, and miR-146a-3p). The average activity of SLE patients IgGs according to median values is statistically significant 84.8-fold higher than that of healthy donors. The hydrolysis of eight microRNAs was mostly site specific. Since inflammatory processes in SLE are associated with the change in miRNAs expression, the decrease in their concentration due to hydrolysis by autoantibodies-abzymes may be important for SLE pathogenesis.
Mild thermolysis of Lewis base stabilized phosphinoborane monomers R 1 R 2 PBH 2 ⋅NMe 3 (R 1 ,R 2 =H, Ph, or t Bu/H) at room temperature to 100 °C provides a convenient new route to oligo‐ and polyphosphinoboranes [R 1 R 2 P‐BH 2 ] n . The polymerization appears to proceed via the addition/head‐to‐tail polymerization of short‐lived free phosphinoborane monomers, R 1 R 2 P‐BH 2 . This method offers access to high molar mass materials, as exemplified by poly( tert ‐butylphosphinoborane), that are currently inaccessible using other routes (e.g. catalytic dehydrocoupling).
We report non-local electrical measurements in a mesoscopic size two-dimensional (2D) electron gas in a GaAs quantum well in a hydrodynamic regime. Viscous electric flow is expected to be dominant when electron-electron collisions occur more often than the impurity or phonon scattering events. We observe a negative nonlocal resistance and attribute it to the formation of whirlpools in the electron flow. We use the different nonlocal transport geometries and compare the results with a theory demonstrating the significance of hydrodynamics in mesoscopic samples.
Aim . To assess the clinical, biochemical, and genetic risk factors for the development of hepatocyte cytolysis syndrome in patients with a combination of fatty liver disease and recrudescence of chronic cardiovascular pathology.

Material and methods . The study included 74 patients with chronic cardiovascular disease (coronary heart disease, chronic heart failure, hypertension) treated in the cardiology department of the Central Clinical Hospital of the Siberian Branch of Russian Academy of Sciences with a normal baseline transaminase level (AST and ALT); 12 of them have increasing of transaminase level on 10-12 days. All patients underwent therapeutic and diagnostic procedures in accordance with the medical standards in Russian Federation. Genotyping of polymorphic loci of the genes of the cytochrome P450 family was carried out using real-time polymerase chain reaction (PCR).

Results . There was no significant correlation between cytolysis syndrome and phenotypic characteristics: gender, age, body mass index. A positive correlation of fatty liver disease with abdominal obesity and body mass index was confirmed. There was no significant correlation between cytolysis syndrome and clinical and biochemical risk factors: comorbidity and lipid profile. The presence of minor minor allele of cytochrome P-450 — CYP2C9, CYP2D6, CYP2C19 genes in a patient with fatty liver disease increases the risk of cytolysis syndrome during CVD therapy. Conclusion . Pharmacogenetic testing of polymorphic variants of cytochrome P-450 — CYP2C9, CYP2D6, CYP2C19 genes is advisable to recommend to patients with cardiovascular diseases and high-risk of liver disorders for a personalized approach to therapy.
К ПРОБЛЕМЕ ПЕРИОДИЗАЦИИ ЯЗЫКА СОВРЕМЕННЫХ РОССИЙСКИХ СМИРассматривается возможность периодизации языка отечественных
We predict the onset of self-induced parametric or Faraday instabilities in a laser, spontaneously caused by the presence of pump depletion, which leads to a periodic gain landscape for light propagating in the cavity.

Application to the case of Raman fiber lasers is described, in good quantitative agreement between our conceptual analysis and numerical modeling.

As a result of the instability, continuous wave oscillation becomes unstable even in the normal dispersion regime of the cavity, and a periodic train of pulses with ultrahigh repetition rate is generated.
Cerebral arteriovenous malformation (AVM) is a congenital brain vessels pathology, in which the arterial and venous blood channels are connected by tangles of abnormal blood vessels. It is a dangerous disease that affects brain functioning causing the high risk of intracerebral haemorrhage. One of AVM treatment methods is embolization—the endovascular filling of the AVM vessel bundle with a special embolic agent. This method is widely used, but still in some cases is accompanied by intraoperative AVM vessels rupture.

In this paper, the optimal scenario of AVM embolization is studied from the safety and effectiveness of the procedure point of view. The co-movement of blood and embolic agent in the AVM body is modelled on the basis of a one-dimensional two-phase filtration model. Optimal control problem with phase constraints arising from medicine is formulated and numerically solved. In numerical analysis, the monotone modification of the CABARET scheme is used. Optimal embolization model is constructed on the basis of real patients' clinical data collected during neurosurgical operations.

For the special case of embolic agent, input admissible and optimal embolization scenarios were calculated.
Рассматриваются уравнения, описывающие трехмерные нестационарные движения смесей теплопроводных вязких сжимаемых жидкостей в рамках многоскоростного подхода. Доказана теорема существования, в целом по времени и входным данным, обобщенного (диссипативного) решения начально-краевой задачи, соответствующей течениям в ограниченной области. Библиография: 36 наименований.
The data on the evolution of the interface at the sudden injection of gas from a long tube into a liquid column was obtained.

High speed video of experiments and calculations in OpenFoam software package were used as research methods. Investigations were performed for different initial pressures.

Typical configurations of the interface for different time periods were shown both experimentally and numerically.