Hengzongshu/ArticleAgent huggingface dataset:
Evolution of thin liquid films sheared by co-current gas stream in a vertical 11.7 mm pipe is studied experimentally using BBLIF technique.

The main goal is to investigate the transition of wave patterns due to increase in the gas stream velocity, VG, from 0 to 24 m/s. Apart from relatively weak quantitative changes in the characteristics of the primary waves, replacement of capillary precursor by slow secondary waves is found. The transition is indentified in the range of VG = 8 - 16 m/s for all liquid flow rates.

It is observed that the appearing secondary waves may be the main reason of the decay of the capillary precursor. The experimental results are compared to prediction of evolutionary theoretical model, showing qualitative agreement on secondary waves generation, but with no agreement on precursor's disappearance. Introducing artificial perturbations mimicking the action of turbulent pulsations in the gas phase is recommended to improve the model.
Genes for height have gained interest for decades, but only recently have candidate genes started to be identified.

We have performed linkage analysis and genome-wide association for height in approximately 4000 individuals from five European populations. A total of five chromosomal regions showed suggestive linkage and in one of these regions, two SNPs (rs849140 and rs1635852) were associated with height (nominal P = 7.0 × 10 −8 and P = 9.6 × 10 −7 , respectively). In total, five SNPs across the genome showed an association with height that reached the threshold of genome-wide significance (nominal P < 1.6 × 10 −7 ). The association with height was replicated for two SNPs (rs1635852 and rs849140) using three independent studies ( n = 31 077, n =1268 and n = 5746) with overall meta P -values of 9.4 × 10 −10 and 5.3 × 10 −8 .

These SNPs are located in the JAZF1 gene, which has recently been associated with type II diabetes, prostate and endometrial cancer. JAZF1 is a transcriptional repressor of NR2C2 , which results in low IGF1 serum concentrations, perinatal and early postnatal hypoglycemia and growth retardation when knocked out in mice. Both the linkage and association analyses independently identified the JAZF1 region affecting human height. We have demonstrated, through replication in additional independent populations, the consistency of the effect of the JAZF1 SNPs on height. Since this gene also has a key function in the metabolism of growth, JAZF1 represents one of the strongest candidates influencing human height identified so far.
Parahydrogen-induced polarization of 13C nuclei by side-arm hydrogenation (PHIP-SAH) for [1-13C]acetate and [1-13C]pyruvate esters with application of PH-INEPT-type pulse sequences for 1H to 13C polarization transfer is reported, and its efficiency is compared with that of polarization transfer based on magnetic field cycling (MFC). The pulse-sequence transfer approach may have its merits in some applications because the entire hyperpolarization procedure is implemented directly in an NMR or MRI instrument, whereas MFC requires a controlled field variation at low magnetic fields. Optimization of the PH-INEPT-type transfer sequences resulted in 13C polarization values of 0.66 ± 0.04% and 0.19 ± 0.02% for allyl [1-13C]pyruvate and ethyl [1-13C]acetate, respectively, which is lower than the corresponding polarization levels obtained with MFC for 1H to 13C polarization transfer (3.95 ± 0.05% and 0.65 ± 0.05% for allyl [1-13C]pyruvate and ethyl [1-13C]acetate, respectively). Nevertheless, a significant 13C NMR signal enhancement with respect to thermal polarization allowed us to perform 13C MR imaging of both biologically relevant hyperpolarized molecules which can be used to produce useful contrast agents for the in vivo imaging applications.
At the molecular level, response to an external factor or an internal condition causes reprogramming of temporal and spatial transcription. When an organism undergoes physiological and/or morphological changes, several signaling pathways are activated simultaneously. Examples of such complex reactions are the response to temperature changes, dehydration, various biologically active substances, and others. Synergistic action of multiple pathways greatly complicates the experimental study of the molecular genetic mechanisms of the organism's reactions. As a result, a significant part of the regulatory ensemble in such complex reactions remains unidentified. We developed metaRE, an R package for the systematic search for cis-regulatory elements enriched in the promoters of the genes significantly changed their transcription in a complex reaction. metaRE mines multiple expression profiling datasets generated to test the same organism's response and identifies simple and composite cis-regulatory elements systematically associated with differential expression of genes. Here we showed metaRE performance for identification of cold stress-responsive cis-regulatory code in Arabidopsis thaliana. MetaRE identified potential binding sites for known as well as unknown cold response regulators. Software with source files, documentation, and example data files are freely available online at the repository (https://github.com/cheburechko/MetaRE).
Background. Agonistic behavior is necessary for formation of dominant-subordinate relationship and for maintenance of social hierarchy in animal communities. However? there are few reports about the genetic features of agonistic behavior development in animals living in stable social groups. The aim of the present study was to investigate the ontogeny of agonistic behavior in male mice of different genotype and social status under stable social hierarchy conditions. Materials and methods. We studied the age dynamics of offensive attacks, the vertical defensive postures and the “runaway” behavior in male mice of inbred strains PT and CBA/Lac housed in genetically heterogeneous pairs during puberty (from 38 to 70 days of life). Results. Dominant-subordinate relationships were stable in 80 % of pairs during the experiment. During the period of stable social hierarchy we observed a transient increase in the number of offensive attacks at the end of puberty in dominants of the strain CBA/Lac but not in PT. Conclusion. In conclusion, the study revealed a significant influence of social rank and genotype on the development of patterns of social behavior in laboratory male mice during puberty.
The largest radiative corrections to the cross section of electron-proton scattering at high energies are associated with emission of photons, real and virtual, by electron. They contain large logarithms coming from soft and collinear photons. Cancellation of the contributions of the soft photons to virtual and real corrections is well known.

Less known is the fact that the contributions of the photons collinear to scattered electrons are also canceled for the most of experiments. On the contrary, contributions of the photons collinear to initial electrons as a rule are not canceled.

It is shown, however, that these contributions are canceled for the experimental set up suggested by A.A. Vorobev for measurement of proton radius.
The paper considers the use of a convolution neural network for detecting first arrivals for a real set of 3D seismic data with more than 4.5 million traces. Detection of the first breaks for each trace is carried out independently.

The error between the original and the predicted first breaks is no more than 3 samples for 95% of the data. Quality control is performed by calculating static corrections and seismic stacks, which showed the effectiveness of the proposed approach.
The CMD-3 detector has been taking data since December 2010 at the VEPP-2000 electron-positron collider.

The collected data sample corresponds to about 60 inverse picobarn of integrated luminosity in the c.m. energy range from 0.32 to 2.0 GeV. Preliminary results of the analysis of various hadronic cross sections, in particular, e+e− → π+π−, π+π−π0, KL KS, K+ K−, ηγ, 3(π+π−), 2(π+π−π0), K+ K−π+π−, K+ K−η, K+ K−π0, ηπ+π−, ωπ+π− and ω → π0e+e− are presented.

The processes with multihadron final states have several intermediate states which have to be taken into account to correctly describe the angular and invariant mass distributions, as well as cross section energy dependence.
Background: Constant blood flow despite changes in blood pressure, a phenomenon called autoregulation, has been demonstrated for various organ systems.

Methods: Electrocardiogram and plethysmograph waveforms were recorded at the left and right index fingers in 18 healthy volunteers. Each subject changed their left arm position, keeping the right arm stationary. Pulse arrival times (PAT) at both fingers were measured and used to calculate PWV. We calculated ΔPAT (ΔPWV), the differences between the left and right PATs (PWVs), and compared them to the respective calculated blood pressure at the left index fingertip to derive the limits of autoregulation.

Conclusions: Changes in hydrostatic pressure due to changes in arm position significantly affect peripheral arterial stiffness as assessed by ΔPAT and ΔPWV, allowing us to estimate peripheral autoregulation limits based on PWV.
We introduce the concept of third-order Riemann pulses in nonlinear optical fibers. These pulses are generated when properly tailored input pulses propagate through optical fibers in the presence of higher-order dispersion and Kerr nonlinearity. The local propagation speed of these optical wave packets is governed by their local amplitude, according to a rule that remains unchanged during propagation. Analytical and numerical results exhibit a good agreement, showing controllable pulse steepening and subsequent shock wave formation. Specifically, we found that the pulse steepening dynamic is predominantly determined by the action of higher-order dispersion, while the contribution of group velocity dispersion is merely associated with a shift of the shock formation time relative to the comoving frame of the pulse evolution. Unlike standard Riemann waves, which exclusively exist within the strong self-defocusing regime of the nonlinear Schrödinger equation, such third-order Riemann pulses can be generated under both anomalous and normal dispersion conditions. In addition, we show that the third-order Riemann pulse dynamics can be judiciously controlled by a phase chirping parameter directly included in the initial chirp profile of the pulse.
Multiple sclerosis is a neurological disorder with poorly understood pathogenic mechanisms and a lack of effective therapies. Therefore, the search for new MS treatments remains very important.

This study was performed on a commonly used cuprizone animal model of multiple sclerosis. It evaluated the effect of a plant-derived substance called Ropren® (containing approximately 95% polyprenols or long-chain isoprenoid alcohols) on cuprizone- induced demyelination. The study was performed on 27 eight-week old male CD-1 mice. To induce demyelination mice were fed 0.5% cuprizone in the standard diet for 10 weeks. Ropren® was administered in one daily intraperitoneal injection (12mg/kg), beginning on the 6th week of the experiment. On the 11th week, the corpus callosum in the brain was evaluated in all animals using magnetic resonance imaging with an 11.7 T animal scanner using T2- weighted sequence.

Cuprizone treatment successfully induced the model of demyelination with a significant decrease in the size of the corpus callosum compared with the control group (p<0.01). Mice treated with both cuprizone and Ropren® did not exhibit demyelination in the corpus callosum (p<0.01). This shows the positive effect of polyprenols on cuprizone-induced demyelination in mice.
The paper presents the results of the numerical simulation of the supersonic (M ∞ = 7) flow around the cylinder with the front gas-permeable porous insert at different angles of attack. The numerical simulation involves the comparative analysis of a number of skeleton models of high-porous cellular materials of the front insert: from the set of coaxial rings of different diameters, and the set of hollow spheres with different spatial resolution. The calculated data of the drag coefficient have been compared with the wind tunnel experiment results.
This approach is based on spectroscopy analysis of Raman light scattering, and avoids the problem of nonstoichiometric binding of dyes to DNA, as it directly measures the signal from DNA.

Here we demonstrate the feasibility of a novel approach to quantify DNA in cell nuclei. Quantitative analysis of nuclear DNA contribution to Raman spectrum could be reliably performed using intensity of a phosphate mode at 1096 cm −1 . When compared to the known DNA standards from cells of different animals, our results matched those values at error of 10%.

We therefore suggest that this approach will be useful to expand the list of DNA standards, to properly adjust the duration of hydrolysis in Feulgen staining, to assay the applicability of fuchsines for DNA quantification, as well as to measure DNA content in cells with complex hydrolysis patterns, when Feulgen densitometry is inappropriate.
In-plane hole g-factors measured in quantum point contacts based on p-type heterostructures strongly depend on the orientation of the magnetic field with respect to the electric current. This effect, first reported a decade ago and confirmed in a number of publications, has remained an open problem. In this work, we present systematic experimental studies to disentangle different mechanisms contributing to the effect and develop the theory which describes it successfully. We show that there is a new mechanism for the anisotropy related to the existence of an additional $B_+k_-^4\sigma_+$ effective Zeeman interaction for holes, which is kinematically different from the standard single Zeeman term $B_-k_-^2\sigma_+$ considered until now.
In this work, the sensor response of MPcFx (M = Cu, Co, Zn; x = 0, 4, 16) films toward gaseous NH₃ (10⁻50 ppm) was studied by a chemiresistive method and compared to that of unsubstituted MPc films to reveal the effects of central metals and F-substituents on the sensing properties. A combination of atomic force microscopy and X-ray diffraction techniques have been used to elucidate the structural features of thin MPcFx films deposited by organic molecular beam deposition. It has been shown that the sensor response of MPcF₄ films to ammonia is noticeably higher than that of MPc films, which is in good correlation with the values of binding energy between the metal phthalocyanine and NH₃ molecules, as calculated by the density functional theory (DFT) method. At the same time, in contrast to the DFT calculations, MPcF16 demonstrated the lesser sensor response compared with MPcF₄, which appeared to be connected with the different structure and morphology of their films. The ZnPcF₄ films were shown to exhibit a sensitivity to ammonia up to concentrations as low as 0.1 ppm, and can be used for the selective detection of ammonia in the presence of some reducing gases and volatile organic compounds. Moreover, the ZnPcF₄ films can be used for the detection of NH₃ in the gas mixture simulating exhaled air (N₂ 76%, O₂ 16%, H₂O 5%, and CO₂ 3%).
We report preliminary results on the measurement of the cross sections of the processes e+e− → K+K−π+π− and e+e− → ϕη in the c.m.energy range from 1.5 GeV to 2 GeV with the CMD-3 detector. The cross sections of these processes agree with BaBar results and have better accuracy.
Silicon pixel detectors are at the core of the current and planned upgrade of the ATLAS experiment at the LHC. Given their close proximity to the interaction point, these detectors will be exposed to an unprecedented amount of radiation over their lifetime. The current pixel detector will receive damage from non-ionizing radiation in excess of 1015 1 MeV neq/cm2, while the pixel detector designed for the high-luminosity LHC must cope with an order of magnitude larger fluence.

This paper presents a digitization model incorporating effects of radiation damage to the pixel sensors. The model is described in detail

and predictions for the charge collection efficiency and Lorentz angle are compared with collision data collected between 2015 and 2017 (⩽ 1015 1 MeV neq/cm2).
The article presents the materials of the Book of the Royal Genealogy (16th century), associated with female images, describes their place in the plot and composition structure (architectonics) of the monument.

The life of the Equal-to-the-Apostles Princess Olga, which opens the Book of the Royal Genealogy, emphasizes the legitimacy of the author’s plan, which includes almost all the stories about princely wives and mothers from brief news to detailed stories. The role of these messages is to celebrate the piety of all branches of the royal family. In the characteristics of female representatives of princely families, the author emphasizes the features noted by him in the life of St. Princess Olga (Elena): loyalty to Orthodoxy, service to the cause of its spread, care for the princely family, enlightenment, participation in the earthly affairs of the church (construction of churches, charity), etc.

The lives of the princesses are included by the author in the architectonic of the Royal Genealogy, harmoniously fitting into the main concept of the monument.
Phosphaferrocenes in combination with coinage metal salts proved to be excellent building blocks in supramolecular chemistry for the buildup of oligomeric and polymeric assemblies.

The synthesis of a series of novel phosphaferrocenes containing the 1,3‐P 2 C 3 i Pr 3 and/or the 1,2,4‐P 3 C 2 i Pr 2 ligand is described herein. The self‐assembly processes of the 1,3‐diphospha‐, 1,2,4‐triphospha‐, and 1,1′,2,3′,4‐pentaphosphaferrocenes with Cu I halides led to the formation of 1D or 2D polymers.

With [Cp*Fe(η 5 ‐P 2 C 3 i Pr 3 )] (Cp* = η 5 ‐C 5 Me 5 ), infinite chains are formed, whereas with [(η 5 ‐P 3 C 2 i Pr 2 )Fe(η 5 ‐P 2 C 3 i Pr 3 )] 1D ladderlike structures are obtained. These are the first polymers containing such a di‐ and pentaphosphaferrocene, respectively. On the other hand, the use of [Cp*Fe(η 5 ‐P 3 C 2 i Pr 2 )] leads to the construction of 2D networks with intact sandwich complexes, which is uncommon for this class of complexes.
We present a supercomputer numerical model for simulating 3D dynamics of dust-gas gravitating circumstellar disk. The model combines SPH method for solving gas dynamical equations, particle-in-cell (PIC) method for solving Vlasov equation, and convolution FFT-based grid method for solving Poisson equation. The approach is based on 3D domain decomposition, sorting of particles with regard to grid cell, and transferring necessary amount of particles between subdomains. The algorithm is aimed to be run on supercomputers with distributed memory and on hybrid supercomputers.
We say that a finite almost simple $G$ with socle $S$ is admissible (with respect to the spectrum) if $G$ and $S$ have the same sets of orders of elements.

Let $L$ be a finite simple linear or unitary group of dimension at least three over a field of odd characteristic. We describe admissible almost simple groups with socle $L$.

Also we calculate the orders of elements of the coset $L	au$, where $	au$ is the inverse-transpose automorphism of $L$.
The fi rst joint study by Russian and Philippine archaeologists addresses an unusual variant of a burial tradition distributed in Island Southeast Asia – burials in anthropomorphic clay jars, found in Ayub Cave (southern Mindanao Island, Philippines), excavated by specialists from the National Museum of the Philippines in 1991–1992, and tentatively dated to 500 BC to 500 AD. Of special interest are lids of jars shaped as painted human heads with individualized facial features and expressions. The fi nds suggest that Ayub Cave was a necropolis of the tribe elite, and that vessels were produced by a special group of potters using elaborate “prestige technologies”. The Ayub ceramic collection has various parallels relating to clay fi gurines and decoration including painting, among Late Neolithic and Early Metal Age assemblages from the Philippines (Luzon, Palawan, and Negros Islands), Indonesia (Sumba, Flores, and Bali Islands), and other regions of the Pacifi c Basin from Japan (Jomon) and Korea (Early Iron Age burials) to Vanuatu Islands (Lapita culture). These parallels suggest that the source of the anthropomorphic symbolism was the Austronesian migration with one of its routes passing from southern China via Taiwan, the northern Philippines, Mariana Islands, and further south to Melanesia and Polynesia.
The spatial resolution of GEM based tracking detectors has been simulated and measured. The simulation includes the GEANT4 based transport of high energy electrons with careful accounting for atomic relaxation processes including emission of fluorescent photons and Auger electrons and custom post-processing, including accounting for diffusion, gas amplification fluctuations, the distribution of signals on readout electrodes, electronics noise and a particular algorithm of the final coordinate calculation (center of gravity). The simulation demonstrates that a minimum of the spatial resolution of about 10 μ m can be achieved with strip pitches from 250 μ m to 300 μ m. For larger pitches the resolution is quickly degrading reaching 80-100 μ m at a pitch of 500 μ m. The spatial resolution of low-material triple-GEM detectors for the DEUTRON facility at the VEPP-3 storage ring is measured at the extracted beam facility of the VEPP-4M collider. The amount of material in these detectors is reduced by etching the copper of the GEMs electrodes and using a readout structure on a thin kapton foil rather than on a glass fibre plate. The exact amount of material in one DEUTRON detector is measured by studying multiple scattering of 100 MeV electrons in it. The result of these measurements is X/X0 = 2.4×10 −3 corresponding to a thickness of the copper layers of the GEM foils of 3 μ m. The spatial resolution of one DEUTRON detector is measured with 500 MeV electrons and the measured value is equal to 35 ± 1 μ m for orthogonal tracks.
The cocrystal of betulin with adipic acid was prepared using a liquid-assisted grinding method. The formation of cocrystal was confirmed by powder X-ray diffraction and IR spectroscopy methods. In order to choose a liquid for preparing cocrystal, solvents of different polarity were compared.

It was shown that cocrystal of betulin with adipic acid was formed if solvents were used during mechanical treatment, in which the increased solubility of adipic acid was observed.
Active DNA demethylation (ADDM) in mammals occurs via hydroxylation of 5-methylcytosine (5mC) by TET and/or deamination by AID/APOBEC family enzymes. The resulting 5mC derivatives are removed through the base excision repair (BER) pathway. At present, it is unclear how the cell manages to eliminate closely spaced 5mC residues whilst avoiding generation of toxic BER intermediates and whether alternative DNA repair pathways participate in ADDM. It has been shown that non-canonical DNA mismatch repair (ncMMR) can remove both alkylated and oxidized nucleotides from DNA.

Here, a phagemid DNA containing oxidative base lesions and methylated sites are used to examine the involvement of various DNA repair pathways in ADDM in murine and human cell-free extracts.

We demonstrate that, in addition to short-patch BER, 5-hydroxymethyluracil and uracil mispaired with guanine can be processed by ncMMR and long-patch BER with concomitant removal of distant 5mC residues. Furthermore, the presence of multiple mispairs in the same MMR nick/mismatch recognition region together with BER-mediated nick formation promotes proficient ncMMR resulting in the reactivation of an epigenetically silenced reporter gene in murine cells. These findings suggest cooperation between BER and ncMMR in the removal of multiple mismatches that might occur in mammalian cells during ADDM.