Hengzongshu/ArticleAgent huggingface dataset:
Aim. To determine the gender differentiation and dynamics for 22 years of psychosocial factors (PSF) of the risk of cardiovascular disease among the population aged 25-64 years in Russia / Siberia (Novosibirsk). Materials and methods. Representative samples of the population of the city of Novosibirsk under the program of the World Health Organization “MONICA-MOPSY” in 1994-1995 were examined. III screening (men - 657, women - 870, 25-64 years old); IV screening project HAPIEE in 2003-2005 (men - 576, women - 1074, 45-64 years old) and V screening in 2013-2016. (men - 427, women - 548, 25-44 years old). We used Spielberger tests, MONICA-MOPSY tests, the Breckman - Sim test, the “Knowledge and attitude to your health” questionnaire. Results. In an open population of 25-64 years old, high levels of anxiety (T), depression (D), life exhaustion (LM), and hostility (B) were higher in women than in men. In the group of 55-64 years over 10 years, women have increased personality T, decreased D and LM. Over 22 years, in the group of 25-34 years, men and women decreased T and MI, but D and B increased, while women decreased T, LM and B and D. grew. Low and high close contact indices were higher among men. A low index of social ties prevailed in men, and a high index in women. High levels of stress in the family were more common in women, and at work - in men. For 10 years, the level of stress in the family and at work in men has decreased. Sleep disorders in the population in all age groups were more often in women. Conclusion. It was found that women have significantly higher PSF than men, with the exception of stress at work. The decrease in PSF in women and men in the dynamics
We have synthesized the orthocarbonate Sr3[CO4]O in a laser-heated diamond anvil cell at 20 and 30 GPa by heating to ≈3000 (300) K. Afterward, we recovered the orthocarbonate with [CO4]4– groups at ambient conditions. Single-crystal diffraction shows the presence of [CO4]4– groups, i.e., sp3-hybridized carbon tetrahedrally coordinated by covalently bound oxygen atoms. The [CO4]4– tetrahedra are located in a cage formed by corner-sharing OSr6 octahedra, i.e., octahedra with oxygen as a central ion, forming an antiperovskite-type structure. At high pressures, the octahedra are nearly ideal and slightly rotated. The high-pressure phase is tetragonal (I4/mcm). Upon pressure release, there is a phase transition with a symmetry lowering to an orthorhombic phase (Pnma), where the octahedra tilt and deform slightly.
Aim To study blood adipokines spectrum in people aged 25-44 years with early ischemic heart disease (IHD), including that associated with abdominal obesity (AO).

Material and methods A cross-sectional study was performed on a random sample of the population aged 25-44 years in Novosibirsk. 1457 subjects (653 men, 804 women) were evaluated. This study included 123 people divided into four study subgroups: subgroup 1, with IHD associated with AO (n=24); subgroup 2, with IHD and without AO (n=25); subgroup 3, without IHD and with AO (n=44); and subgroup 4, without either IHD or AO (n=30). Concentrations of serum adipokines were measured simultaneously by multiplex assay with a Luminex MAGPIX flow fluorometer and by immune enzyme assay with a MULTISCAN analyzer.

Conclusion In young people aged 25-44 years, lower blood concentrations of MCP-1 were associated with a likelihood of early IHD, including that associated with AO.
The review is devoted to consideration of possible observational consequences of modified gravity theories, suggested for explanation of the contemporary accelerated expansion of the universe. The major attention is paid to F(R)-models. It is shown that in systems with rising energy density high frequency and large amplitude oscillations of the curvature scalar, R(t), are induced. These oscillations lead to the production of elementary particles, which may be observed in the spectra of energetic cosmic rays. In the background of such oscillating solutions gravitation repulsion between finite-size objects becomes possible. Since the Lagrangian is a non-linear function of curvature, equations of motion become of higher (4th) order and exhibit very rich pattern of new physical effects. In particular, the evolution of density perturbations is strongly different from that in General Relativity, amplified due to both parametric resonance and anti-friction phenomena.
Curved mountain belts, commonly referred as to oroclines that result from bending of quasi-linear orogenic belts, have fascinated generations of geologists. Such structures are widely recognized in modern and ancient orogens, and are fundamentally important for understanding geodynamics of convergent plate boundaries.

Here we investigate the Kazakhstan Orocline in the Central Asian Orogenic Belt with an aim at understanding the geodynamics of oroclinal bending in accretionary orogens.

However, how and why orogenic belts become bent has been in debate.
Long-range weapons being of a certain scientific interest, the samples of spearheads considered are important as they have not been described yet.

In the course of our research, we have analyzed the features of their design in order to clarify the origin and time of their creation.

Three previously unknown spearheads have been introduced into scientific circulation. The analysis of the design features of these weapons allowed us to date them to the 17th century. The spearheads are attributed to the type 'rogatina', which was widespread in the Russian state being massive and big. Such long-range weapons were known as 'bear-spear' and initially were used for hunting large animals. Such items are widely found in the European part of Russia and in Siberia, where they were brought by Russian pioneers.
MicroRNAs (miRNA) are short 21-23nt RNAs capable of inhibiting translation of complementary target messenger RNAs. Almost half of D. melanogaster miRNA genes are grouped in genomic clusters.

The peculiarities of the expression of clustered miRNAs were studied using publicly available libraries of sequenced small RNAs from different Drosophila tissues. We have shown that although miRNAs from almost all clusters have similar tissue expression profiles (coordinated clusters), some clusters contain miRNAs with uncoordinated expression profiles. The predicted transcription start sites (TSSs) of such clusters are located upstream of the first miRNA, but no TSSs are found within the clusters. The expression profiles of miR and miR* sequences in uncoordinated clustered miRNAs do not correlate while their profiles from the coordinated clustered miRNAs are similar.

The presence of exclusively upstream promoters in miRNA clusters containing uncoordinated miRNAs means that the clusters are transcribed as single transcription units. The difference of tissue expression profiles of uncoordinated miRNAs and the corresponding miRs* suggests a post-transcriptional regulation of their processing or stability.
The CMD-3 detector has been collecting data since 2010 at the e+e− collider VEPP-2000 in the Budker Institute of Nuclear Physics. VEPP-2000 uses the novel round beam technique and provides high luminosity in a wide c.m.energy range from 0.32 to 2 GeV. The physics goal of the CMD-3 experiment is a study of the e+e− annihilation into hadrons. CMD-3 is a general-purpose detector, which provides high efficiency for both charged and neutral particles. The electromagnetic calorimeter consists of the barrel calorimeter based on liquid xenon and CsI crystals, and the endcap calorimeter based on BGO crystals. The main parameters of the calorimeters are presented.
D-glucuronyl C5-epimerase (GLCE) is a potential tumor-suppressor gene involved in heparan sulfate biosynthesis. GLCE expression is significantly decreased in breast tumors; however, the underlying molecular mechanisms remain unclear. This study examined the possible epigenetic mechanisms for GLCE inactivation in breast cancer. Very little methylation of the GLCE promoter region was detected in breast tumors in vivo and in breast cancer cells (MCF7 and T47D) in vitro and GLCE expression in breast cancer cells was not altered by 5-deoxyazacytidine (5-aza-dC) treatment, suggesting that promoter methylation is not involved in regulating GLCE expression. Chromatin activation by Trichostatin A (TSA) or 5-aza-dC/TSA treatment increased GLCE expression by two to 3-fold due to an increased interaction between the GLCE promoter and the TCF4/β-catenin transactivation complex, or H3K9ac and H3K4Me3 histone modifications. However, ectopic expression of TCF4/β-catenin was not sufficient to activate GLCE expression in MCF7 cells, suggesting that chromatin structure plays a key role in GLCE regulation. Although TSA treatment significantly repressed canonical WNT signaling in MCF7 cells, it did not influence endogenous TCF4/β-catenin mRNA levels and activated TCF4/β-catenin-driven transcription from the GLCE promoter, indicating GLCE as a novel target for TCF4/β-catenin complex in breast cancer cells. A correlation was observed between GLCE, TCF4 and β-catenin expression in breast cancer cells and primary tumors, suggesting an important role for TCF4/β-catenin in regulating GLCE expression both in vitro and in vivo. Taken together, the results indicate that GLCE expression in breast cancer is regulated by a combination of chromatin structure and TCF4/β-catenin complex activity.
В последние годы все чаще вопрос реабилитации больных алкоголизмом сдвигается из медико-биологической в социально-психологическую область.В связи с этим острее встает тема ключевых различий в личности здоровых людей и зависимых, т. к. только опираясь на эти данные, мы можем выстраивать реабилитационные программы.

Целью проведенного исследования было выявление личностных особенностей людей с алкогольной аддикцией методами психологической диагностики.Для исследования в экспериментальную группу были отобраны мужчины с диагнозом алкоголизм второй стадии, в контрольную группуздоровые мужчины, не имеющие в анамнезе алкоголизма.В качестве методов диагностики были использованы психологические методики для диагностики уровня субъективного контроля, тревожности, уровня социальной фрустрированности, защитных механизмов и самооценки.

Анализ результатов показал ключевые различия между пациентами наркологического диспансера и контрольной выборкой.Значение локуса контроля у больных алкоголизмом ниже на 69 %, чем у здоровых людей.В контрольной выборке выявлен интернальный локус контроля.В диапазон «оптимального» уровня притязаний попадает всего 19 % пациентов, больных алкоголизмом.Эти данные свидетельствует о незрелости личности, неумении ставить реальные цели, нежелании развиваться.Наличие ведущих механизмов защиты сигнализирует об отказе личности от продуктивного разрешения ситуации.У пациентов уровень социальной фрустрированности выше, чем у здоровых людей на 51 %
Newly synthesised molibdenum diimino clusters interact with alkynes

leading to dithiolene species
Cell‐surface‐bound extracellular DNA (csbDNA) is present on the outer membrane of blood cells, including both red blood cells and leukocytes. Although less well characterized than cell‐free DNA (cfDNA) in plasma and serum, leukocyte and red blood cell csbDNA form a considerable fraction of the blood extracellular nucleic acids pool, with typically at least comparable amount of DNA occurring bound to the outer surface of cells as compared with circulating free DNA in plasma. The cellular origin of csbDNA is not clear; however, as with cfDNA, in patients with cancer a proportion is derived from the tumor, thus making it potentially a useful source of DNA for cancer diagnosis, prognosis, and monitoring. © 2019 IUBMB Life, 71(9):1201–1210, 2019
The first measurements of differential branching fractions of inclusive semileptonic B→X_{u}ℓ^{+}ν_{ℓ} decays are performed using the full Belle data set of 711 fb^{-1} of integrated luminosity at the ϒ(4S) resonance and for ℓ=e, μ. With the availability of these measurements, new avenues for future shape-function model-independent determinations of the Cabibbo-Kobayashi-Maskawa matrix element |V_{ub}| can be pursued to gain new insights in the existing tension with respect to exclusive determinations.

They are obtained by subtracting the backgrounds from semileptonic B→X_{c}ℓ^{+}ν_{ℓ} decays and other processes, and corrected for resolution and acceptance effects.

The differential branching fractions are reported as a function of the lepton energy, the four-momentum-transfer squared, light-cone momenta, the hadronic mass, and the hadronic mass squared.
When utilize the sensors with aerodynamic models an issue of influence of model-sensor joint on measurements appears.

The work presents the results of development of panoramic interferential technique to register pressure fields. The technique is based upon the usage of elastic layer as a pressure sensor. Numerical simulations showed a transfer function of the sensor is not affected by the vicinity of the joint to the point of load application.

Nevertheless experimental results demonstrate redistribution of layer transfer function amplitude from low frequency range to high one, 5% relative value change is observed.
The bubble evolution as well as the time-averaged volume-fraction distributions have been compared with prior simulations conducted using MFIX, Barracuda and also with experimental data found in literature.

This work evaluates the effectiveness of the Two-Fluid Model (TFM) to simulate gas flows with dense particles by using a simplified Fluidized Bed as a test case. This document includes the simulations performed using two drag models, namely Gidaspow and Syamlal-O'Brien, using Ansys Fluent 18.1.

Though the low computational requirements and capability to produce reasonable time-averaged results makes TFM a better choice for industrial applications, the low prediction accuracy for the instantaneous quantities often renders it unsuitable for more scientifically demanding studies. Hence, this work aims at a critical evaluation of the TFM model for the specified test problem.
We report a study of the magnetic field dependence of photoluminescence of NV$^-$ centers (negatively charged nitrogen-vacancy centers) in diamond single crystals. In such a magnetic field dependence characteristic sharp features are observed, which are coming from Level Anti-Crossings (LACs) in a coupled electron-nuclear spin system.

For sensitive detection of such LAC-lines we use lock-in detection to measure the photoluminescence intensity. This experimental technique allows us to obtain new LAC lines. Additionally, a remarkably strong dependence of the LAC-lines on the modulation frequency is found. Specifically, upon decrease of the modulation frequency from 12 kHz to 17 Hz the amplitude of the LAC-lines increases by approximately two orders of magnitude. To take a quantitative account for such effects, we present a theoretical model, which describes the spin dynamics in a coupled electron-nuclear spin system under the action of an oscillating external magnetic field.

Good agreement between experiments and theory allows us to conclude that the observed effects are originating from coherent spin polarization exchange in a coupled spin system comprising the spin-polarized NV$^-$ center. Our results are of great practical importance allowing one to optimize the experimental conditions for probing LAC-derived lines in diamond crystals comprising NV$^-$ centers and for indirect detection and identification of other paramagnetic defect centers.
A review of the astronomical data of several last years on an astonishingly high amount of blackholes in the contemporary and early (z∼10) universe is presented. Also the data on the recentlyobserved peculiar stars in the Galaxy are discussed. It is argued that practically all black holes inthe universe are primordial (PBH) and suggested that an inverted picture of the galaxy formationis realized: supermassive black holes were formed prior to galaxy formation and subsequentlyseeded the latter. Possibilities of cosmological dark matter consisting of primordial black holesand of abundant cosmological antimatter are considered.A mechanism of 1993 anticipating all these phenomena and predicting an extended log-normalmass spectrum of PBH is described.
Summary Retrotransposons are the major component of plant genomes. Chromodomain‐containing Gypsy long terminal repeat (LTR) retrotransposons are widely distributed in eukaryotes. Four distinct clades of chromodomain‐containing Gypsy retroelements are known from the vascular plants: Reina, CRM, Galadriel and Tekay. At the same time, almost nothing is known about the repertoire of LTR retrotransposons in bryophyte genomes. We have combined a search of chromodomain‐containing Gypsy retroelements in Physcomitrella genomic sequences and an experimental investigation of diverse moss species. The computer‐based mining of the chromodomain‐containing LTR retrotransposons allowed us to describe four different elements from Physcomitrella. Four novel clades were identified that are evolutionarily distinct from the chromodomain‐containing Gypsy LTR retrotransposons of other plants.
This paper reports a current status of the measurement of the hadronic cross sections in the c.m. energy range from 0.32 to 2.0~GeV

with the CMD-3 detector at the VEPP-2000 electron-positron collider. The overall size of the data, acquired by the CMD-3 in the runs of 2010-2013 and 2017-2019 years, is about 250~$\rm pb^{-1}$

The recent results of data analysis for various exclusive modes of $e^+e^-{\to}hadrons$ are described.
This work summarizes results of synchrotron radiation (SR) studies of the real/defect structure of nanocrystalline/nanocomposite oxide materials, which determines their functional properties in hydrogen energy field as catalysts and mixed ionic electronic conductors (cathodes and anodes of solid oxide fuel cells, oxygen separation membranes).

For nanocrystalline ceria-zirconia mixed oxide prepared via modified Pechini route using ethanol solution of reagents, a high spatial uniformity of cations distribution between domains along with the oxygen sublattice deficiency revealed by full-profile Rietveld refinement of SR diffraction data provide structure disordering enhancing oxygen mobility. For PrNi0.5Co0.5O3–δ – Ce0.9Y0.1O2–δ nanocomposite extensive transfer of Pr cations into fluorite domains generates a new path of fast oxygen diffusion along chains of Pr3+ – Pr4+ cations as directly proved by analysis of the unit cell relaxation after changing pO2 in perfect agreement with data obtained by oxygen isotope heteroexchange.

The studies demonstrate enhanced oxygen mobility through structure disordering and new paths of fast oxygen diffusion in nanocrystalline/nanocomposite oxide materials, which improves their functional properties for hydrogen energy applications.
We experimentally demonstrate a pulsed operation in a random fiber laser operation via self-gain-switching. The pulses have low timing jitter and high average output power. We show that repetition rate switches abruptly while varying the pump power, and introduce a simple formula for oscillation frequencies.
При распараллеливании решения трехмерных краевых задач на квазиструктурированных сетках методом декомпозиции расчетной области на подобласти, сопрягаемые без наложения, наиболее трудоемкой вычислительной процедурой является решение краевых подзадач в подобластях. Использование параллелепипедальных квазиструктурированных сеток дает возможность применить для этих целей быстросходящиеся методы переменных направлений.

Распараллеливание итерационного процесса по подобластям проводится на CPU в системе MPI, а для решения подзадач в настоящей статье предлагается использовать графические ускорители GPU. Приводятся экспериментальные исследования применения графических ускорителей при решении подзадач методом Писмана-Речфорда.

Даются экспериментальные оценки ускорения распараллеливания в гибридной вычислительной среде CPU+GPU по сравнению с расчетами только на CPU.
The American mink (Mustela vison) represents the large family Mustelidae. The family belongs to the order of Carnivora and includes many dozens of species living in a broad range of biotopes, from the Arctic to tropical zones. Carnivores are of great interest in comparative gene mapping in mammals. Giemsa banding with trypsin analysis has shown that chromosome divergence in Mustelidae, despite the considerable variation in number and morphology of chromosomes, mainly resulted from rearrangements of virtually constant elements, probably representing the remains of an ancestral karyotype (Graphodatsky and others 1989; Wuster-Hill and Centerwall 1982). A similar situation was reported in the families Canidae and Ursidae (Graphodatsky and others 1995; Nash and O'Brien 1987; Wurster-Hill and Centerwall 1982). Moreover, the comparison of the Giemsabanding chromosomes of Carnivora and species belonging to other orders—primates, rodents, or ungulates—demonstrated that in some cases there is a similarity in the Giemsabanding patterns for large chromosome regions of the distantly related species (Graphodatsky 1989; Nash and O'Brien 1982). However, supplementary data on gene mapping are needed to decide whether this similarity reflects true homology and to reach reliable conclusions about the chromosome evolution of mammals (O'Brien and others 1993; Wakefield and Graves 1996).

For a long time, the efforts of mink breeders were focused on the identification of mutations affecting coat color genes. At the time of this writing, approximately 30 coat color mutations have been identified in mink. Most of them (at least 20) are controlled by independent autosomal loci (Nes and others 1988; Robinson 1975; Shackelford 1948). It is reasonable to expect that some of them are linked because a haploid set of mink chromosomes contains 14 autosomes plus the X or Y sex chromosome (Christensen and others 1996; Mandahl and Fredga 1975). However, there has been only 1 description of linkage of 2 coat color mutations, Ebony (Eb) and royal pastel (b) (Shackelford 1949). In this paper, I present the current state of gene mapping of mink, based on data obtained from traditional breeding, somatic cell hybridization, chromosome-mediated or interphase nuclei-mediated gene transfer procedures, and in situ hybridization.
Рассматриваются лексико-семантические варианты лексемы ðàçîóìú в славянском переводе Корпуса Ареопагитик, выполненном во второй половине XIV в. на Афоне двуязычным сербским монахом и в его же предисловии к переводу.

Критериями выделения отдельных лексико-семантических вариантов анализируемой лексемы были греческий эквивалент, показания микро-и макроконтекста, в некоторых случаях -современный перевод данного отрывка с греческого языка.

В таком распределении лексико-семантических вариантов состоит отличие рассматриваемого идиолекта как от старославянского, так и от современного русского языка.