Hengzongshu/ArticleAgent huggingface dataset:
We studied the position and motion of poles of Lorenz-Mie (LM) coefficients, responsible for LM resonances, in the space of complex parameters: the size, the refractive index of the sphere, and the refractive index of the host medium.

We performed a comprehensive theoretical analysis and classified all resonances according to their asymptotic behavior and origin. In particular, we proved a few lemmas concerning the logarithmic derivatives of Riccati-Bessel functions and used them to prove the absence of LM poles in some areas of the complex plane (depending on the host medium). We also performed extensive numerical calculations of pole trajectories,

which fully confirm all theoretical predictions and provide additional details in the intermediate range of size parameters.
Nonlinear wave formation and heat transfer in wavy film flowing over the isothermal wall in the present of phase transition are studied numerically.

The integral-boundary-layer model, modified with account of the phase change at the interface has been used to describe the wave motion. For the first time the nonlinear evolution of forced two-dimensional waves was investigated, and wave effect on heat transfer was determined.

It is shown that forced waves essentially intensify heat transfer within a certain range of frequencies as compared to the case of naturally occurring waves. Heat transfer enhancement by waves due to the predominant contribution of the thin residual layer between the peaks was demonstrated. It is shown that by applying the superimposed periodic oscillations, one can intensify heat transfer within a certain range of frequencies as compared to the case of naturally occurring waves.
One of the most widespread prokaryotic symbionts of invertebrates is the intracellular bacteria of Wolbachia genus which can be found in about 50% of insect species. Wolbachia causes both parasitic and mutualistic effects on its host that include manipulating the host reproductive systems in order to increase their transmission through the female germline, and increasing the host fitness. One of the mechanisms, promoting adaptation in biological organisms, is a non-specific neuroendocrine stress reaction. In insects, this reaction includes catecholamines, dopamine, serotonin and octopamine, which act as neurotransmitters, neuromodulators and neurohormones. The level of dopamine metabolism correlates with heat stress resistance in Drosophila adults.

To examine Wolbachia effect on Drosophila survival under heat stress and dopamine metabolism we used five strains carrying the nuclear background of interbred Bi90 strain and cytoplasmic backgrounds with different genotype variants of Wolbachia (produced by 20 backcrosses of Bi90 males with appropriate source of Wolbachia). Non-infected Bi90 strain (treated with tetracycline for 3 generations) was used as a control group.

We demonstrated that two of five investigated Wolbachia variants promote changes in Drosophila heat stress resistance and activity of enzymes that produce and degrade dopamine, alkaline phosphatase and dopamine-dependent arylalkylamine N-acetyltransferase. What is especially interesting, wMelCS genotype of Wolbachia increases stress resistance and the intensity of dopamine metabolism, whereas wMelPop strain decreases them. wMel, wMel2 and wMel4 genotypes of Wolbachia do not show any effect on the survival under heat stress or dopamine metabolism. L-DOPA treatment, known to increase the dopamine content in Drosophila, levels the difference in survival under heat stress between all studied groups. The genotype of symbiont determines the effect that the symbiont has on the stress resistance of the host insect.
This paper presents a novel miniature module of orientation sensors for CubeSat nanosatellites. A high-precision sun sensor and a detector of the Earth horizon are located in one small module body. A two-axis digital sun sensor built into the orientation module is based on the registration of the sunspot formed on the matrix CMOS image sensor when the sun’s rays pass through a pinhole in the front mask. A commercially available miniature array of infrared thermometers is used as the Earth horizon sensor. The paper is mainly devoted to the development of the sun sensor. For laboratory tests, a prototype of the orientation module was developed. Laboratory tests and sun sensor calibration confirmed the sun sensor field of view of 120° and made it possible to determine its angular resolution of ±0.015°. The final accuracy of determining the direction to the Sun by the sensor that was calibrated using the existing experimental setup is ±0.15° with 95% confidence. It is possible to improve the accuracy of the sun sensor by improving the experimental setup for its calibration.
Germinating ability of winter and winterspring hexaploid triticale seeds, as well as wheat and rye seeds, after nine years of room storage at the temperature of 18-24°C, was studied. The experiment was laid in autumn 2008 and included four repetitions of crop samples within each storage variant: in ears and threshed seeds, in paper and plastic bags. For the experiment, the seeds of the new harvest were dried for 2 months in sheaves. In autumn 2017, the seeds were germinated at the temperature of 24 °C. The most acceptable variants of seed storage (in plastic bags and in ears) as well as differences in seed germinating ability of crops and variety specimens of different development types were revealed. Seed germinating ability of all three crops was satisfactory when stored in ears (68 ± 3%) and in plastic bags (70 ± 3%). Reduced germinating ability (59 ± 2%) was noted after storage in paper bags. When stored in plastic bags, the seeds of winter varieties of triticale, Sears 57 and Cecad 90, showed increased germinating ability: 77 ± 3% and 74 ± 2%, respectively. The seed germinating ability of all winter crops was higher than that of winterspring analogues. Triticale excess averaged 9%, wheat - 4.5%, winter rye - 12%. Among all studied crops and samples, the most late-maturing genotype of winter-spring triticale Cecad 90/5 had the lowest seed germinating ability (45 ± 3%), while winter rye variety Korotkostebelnaya 69 had the highest one (84 ± 4%). The diploid rye had an average seed germination rate by 11% higher than the tetraploid one. Wheat and rye had higher seed germinating ability in all variants of the experiment than triticale genotypes, the germinating ability indices being 72 ± 3%, 68 ± 3% and 61 ± 2%, respectively.
Traditional nuclear magnetic resonance (NMR) spectroscopy relies on the versatile chemical information conveyed by spectra. To complement conventional NMR, Laplace NMR explores diffusion and relaxation phenomena to reveal details on molecular motions. Under a broad concept of ultrafast multidimensional Laplace NMR, here we introduce an ultrafast diffusion-relaxation correlation experiment enhancing the resolution and information content of corresponding 1D experiments as well as reducing the experiment time by one to two orders of magnitude or more as compared with its conventional 2D counterpart. We demonstrate that the method allows one to distinguish identical molecules in different physical environments and provides chemical resolution missing in NMR spectra. Although the sensitivity of the new method is reduced due to spatial encoding, the single-scan approach enables one to use hyperpolarized substances to boost the sensitivity by several orders of magnitude, significantly enhancing the overall sensitivity of multidimensional Laplace NMR.
Purpose: The article examines the topos of HOME and following motifs A. P. Chekhov’s late prose. Results: The 1st story, A Woman’s Kingdom, portrays a rich young woman who is bored with her eventless everyday life. Being clever and open-hearted, Anna Akimovna searches for human values, such as empathetic communication, loving family, etc. The fictive time is Christmas Eve and Christmas Day, so genre tradition of Christmas narratives involves miracles connected with status changes (marriage, family reunification, poor relative gets award or gift from their rich uncle, an orphan finds their parents, and so on). Ritual temporality suggests some fate changes, and it makes Anna Akimovna dream about her matrimony matters with the worker Pimenov. At last she realizes that Pimenov is below her socially, and social instinct leads her closer to vapid and stupid such as Lysevich or important administrative official Krylin. Dull days she spends at home compel her to leave her dreams for humility. Thus, home-associated motifs in the story are boredom, weariness, and humility. The second narrative, At Home, is based on a return plot. Vera Kardina, who has received her education courses in Moscow, suffers from primitive customs of her home estate. Eventually, she realizes that she is becoming as rude and narrow-minded as the others inhabitants. Therefore, she decides to escape into an unhappy marriage. Corresponding motifs are the same: boredom and weariness, but the main character’s escape reveals the higher degree of disagreement with her current lifestyle. In the third short story, A Doctor’s Visit, the female character’s disease is explained by her inner anxiety related to her social role. Liza Lyalikova is the heir of a huge factory, but she worries that it makes her unhappy and lonely. Doctor Korolev is sure that the best way for Liza’s recovery is to quit the business. When the characters meet next morning, doctor believes that Liza would leave home. Both characters compare the factory with the devil, the absolute evil force, that forms the main motif of the short story. Here, the HOME topos is reconstructed in symbolic way. Conclusion: We conclude that the topos of home in Chekhov’s late works produces destructive emotions. Main characters of narratives don’t feel safe and calm in their homes. Motif dynamics show the development of characters’ positions from humility to deliverance.
A method for circular e$^-$/e$^+$ accelerator beam energy measurement is proposed. Coordinate of an electron (or a positron) in a focusing magnetic spectrometer built in a circular accelerator depends on its energy, two spectrometer parameters, and the circulating beam energy. The spectrometer parameters can be defined using minimum electron energies from Compton backscattering with two laser wavelengths, and an additional photon coordinate detector. The photon detector is calibrated at once at well-known beam energy. The VEPP-4M collider has appropriate equipment for the method implementation: built-in focusing magnetic spectrometer, Compton calibration system with two lasers and a photon coordinate detector. Thus, the proposed technique could be implemented with minimum efforts; tests and further upgrade are planned. The beam energy can be defined with expected uncertainty better than $10^{-4}$.
Dust particles were formed in the process of coagulation of ethanol dissociation products in the plasma of gas discharge.

The formation of elongated dust particles in a spherical dc glow discharge in ethanol was observed for the first time. During the process the particles were captured into clouds in the electric potential wells of strong striations of spherical discharge. The size and the shape of dust particles are easily detected by naked eye after the illumination of the laser sheet.

The description of the experimental setup and conditions, the analysis of size, shape and composition of the particles, the explanation of spatial ordering and orientation of these particles are presented.
Каменная технология среднего этапа верхнего палеолита Северной Монголии

культурный горизонт 2 стоянки Толбор-21
Background: Earlier we discovered transactivation of the HIV-1 and hepatitis B virus (HBV) in human cells by 30-300 ppt dioxin, a xenobiotic with extremely long serum half-life in humans. Also, upregulation of cytomegalovirus (HCMV) in human cells was shown by 10 ppq dioxin whereas current its background level in general population is ∼4 ppt. So, human viruses were suggested novel target genes of cellular dioxin receptor (AhR/Arnt) complex. The complex was known as binding to dioxin-responsive elements (DRE) within mammalian genes, and amount of DREs determine level of target gene activation. Methods: Productions of infectious HIV-1 in MT4 cells, HCMV in THP-1 cells, and HBV in HepG2 cells were determined using plaque assay. Viral DNAs were determined by hybridization and PCR. A computational search for viral DRE was performed by SITECON, a tool for detecting transcription factor binding site alignments/site recognition. Results: A total of 13 bona fide DRE, all including the substitution intolerant core sequence (5'-GCGTG-3') and SITECON-selected adjacent variable sequences were used here to detect the above properties for the DRE site, and conformational similarity score threshold of 0.95 was utilized to rank identified DRE. It was found that regulatory region of HCMV genes encoding IE gp/UL37 has 5 DRE, 1.65 kb/UL36 – 6 DRE, pp65 – 7 DRE, pp71 – 7 DRE, and pp150 –10 DRE. Wile juxtaposing DRE contents with experimental results, the most susceptible candidate virus to be augmented with body burden dioxin is that one possessing at least similar to HCMV amount of DRE. SITECON recognized several cancer-associated human viruses possessing multiple DREs in their promoters. Thus Epstein-Barr virus (EBV) promoters L1A and L1 each contain 16 DRE, and gene of EBV R1 145K - 11 DRE. Genes encoding some major proteins of herpes simplex virus (HSV) type 1 have from 7 to 8 promoter DRE. Conclusion: The above support the concept, and provide evidence that sub-nanomolar dioxin is able to activate DRE-containing viruses. Mechanistic data obtained allow searching for inhibitors of viremia and virally-driven malignancies among antagonist ligands of cytosolic Ah receptor, and modifiers of AhR/Arnt complex binding to viral DRE.
The article examines the concept and qualifying features of business activity as an inter-branch law category based on the theory of civil, business, criminal, administrative and financial law.

The authors stress the importance of finding efficient solutions for optimizing the basic concept of entrepreneurial activities

to eliminate the possibility of using criminal prosecution to exert pressure on entrepreneurs and to solve business disputes.In its turn, this will allow
Background: Transcription factors (TFs) are main regulators of eukaryotic gene expression. The cooperative binding to genomic DNA of at least two TFs is the widespread mechanism of transcription regulation. Cooperating TFs can be revealed through the analysis of co-occurrence of their motifs. Methods: We applied Motifs Co-Occurrence Tool (MCOT) that predicted pairs of spaced or overlapped motifs (composite elements, CEs) for a single ChIP-seq dataset. We improved MCOT capability for prediction of asymmetric CEs with one of participating motifs possessing higher conservation than another does. Results: Analysis of 119 ChIP-seq datasets for 45 human TFs revealed that almost for all families of TFs the co-occurrence with an overlap between motifs of target TFs and more conserved partner motifs was significantly higher than that for less conserved partner motifs. The asymmetry toward partner TFs was the most clear for partner motifs of TFs from ETS family. Conclusion: Co-occurrence with an overlap of less conserved motif of a target TF and more conserved motifs of partner TFs explained a substantial portion of ChIP-seq data lacking conserved motifs of target TFs. Among other TF families, conservative motifs of TFs from ETS family were the most prone to mediate interaction of target TFs with its weak motifs in ChIP-seq.
Based on the generalized Cayley transform, a family of conservative one-step schemes of the sixth order of accuracy for the Zakharov-Shabat system is constructed. The exponential integrator is a special case. Schemes based on rational approximation allow the use of fast algorithms to solve the initial problem for a large number of values of the spectral parameter.
MicroRNAs (miRNAs) play important roles in the regulation of gene expression at the post-transcriptional level. Many exogenous compounds or xenobiotics may affect microRNA expression. It is a well-established fact that xenobiotics with planar structure like TCDD, benzo(a)pyrene (BP) can bind aryl hydrocarbon receptor (AhR) followed by its nuclear translocation and transcriptional activation of target genes. Another chemically diverse group of xenobiotics including phenobarbital, DDT, can activate the nuclear receptor CAR and in some cases estrogen receptors ESR1 and ESR2.

We used in silico methods to find DRE, PBEM, ERE potential binding sites for these receptors, respectively. We have predicted AhR, CAR, and ESRs binding sites in 224 rat, 201 mouse, and 232 human promoters of miRNA-coding genes.

We have identified a number of miRNAs with predicted AhR, CAR, and ESRs binding sites that are known as oncogenes and as tumor suppressors. Our results, obtained in silico, open a new strategy for ongoing experimental studies and will contribute to further investigation of epigenetic mechanisms of carcinogenesis.
ABSTRACT Expansins facilitate cell expansion via mediating pH-dependent cell wall (CW) loosening. However, the role of expansins in the control of biomechanical CW properties in the tissue and organ context remains elusive. We determined hormonal responsiveness and specificity of expression and localization of expansins predicted to be direct targets of cytokinin signalling. We found EXPA1 homogenously distributed throughout the CW of columella/ lateral root cap, while EXPA10 and EXPA14 localized predominantly at the three-cell boundaries of epidermis/cortex in various root zones. Cell type-specific localization of EXPA15 overlaps with higher CW stiffness measured via Brillouin light scattering microscopy. As indicated by both Brillouin frequency shift and AFM-measured Young’s modulus, EXPA1 overexpression upregulated CW stiffness, associated with shortening of the root apical meristem and root growth arrest. We propose that root growth in Arabidopsis requires delicate orchestration of biomechanical CW properties via tight regulation of various expansins’ localization to specific cell types and extracellular domains.
Molecular mechanisms of human disease progression often have complex genetic underpinnings

sophisticated sequencing approaches coupled with advanced analytics
Purpose. Archaeological findings on the western Caspian coast indicate that this part of the Caucasus was populated throughout the Pleistocene. The earliest human habitation in the region is dated back to around 2 million years ago (2 Ма), which corresponds to the period of initial expansion of early Homo beyond Africa. Information on the environment and the features of the early human material culture is crucial for our understanding of the Caucasus’ earliest history. It was alternating processes of transgression and regression of the Caspian Sea throughout the Pleistocene that determined the paleoenvironment in the eastern Caucasus. The Early Pleistocene landscape of the southeastern part of Eastern Europe and northeastern Caucasus was similar to African open landscapes nowadays. The Khapry faunal complex characterizes the environment of that period. Its vertebrate composition is close to that typical for African savanna. Both animal communities included similar types of large herbivores: the elephant, rhinoceros, antelope, giraffe, ostrich and others. The African savanna carnivore community included the lion, guepard, hyena and jakal. The Khapry complex included the hyena, large sabre toothed Felidae, guepard and others. The earliest artifact collections in the Northeastern Caucasus are the artifact assemblage from stratum 5 at Rubas-1 in southeastern Dagestan and the archaeological materials from Ainikab-1, Mukhai-1 and 2 in Central Dagestan. The artifact age has been estimated in the range of ~ 2.3–1.8 Ma. Results. The initial stage of human habitation of the Northeastern Caucasus is characterized by two distinct lithic industries: the small tool industry (Rubas-1, stratum 5) and the Oldowan / pebble-flake industry (the Akushinski group of sites). Early human populations dispersed rather rapidly over the low-altitude savannas in the relative proximity to the seashore under the favorable environmental conditions of the initial Pleistocene. After the initial peopling stage, human communities set apart in particular regions where lithic industries were formed and developed. The first major region represents the Caspian shores (the small tool industry: Rubas-1); the second zone is the higher plateaus at the altitude not exceeding 1 500 m asl (pebble-flake industry: Dmanisi, Central Dagestan sites). Conclusion. It is asserted that the early human populations migrating out of Africa through Western Asia to the Caucasus, and its eastern part in particular, remained in the habitual environment, and it did not require any substantial changes in the adaptation strategies including stone working techniques and lithic tool production.
The article presents an algorithm for modeling fertility factors, which are discrete variables, taking into account endogeneity. Cross-sectional data for individuals is used. The main factors influencing the probability of having a child within the next year and the number of children a woman has are described.
The possibility of physics beyond the standard model is studied. The requirement of finiteness of the zero point energy density and pressure or the requirement of the Lorentz invariance of the zero point stress-energy tensor in Minkowski space-time, implies regularization sum rules on the number of degrees of freedom and mass of fundamental particles spectrum.

The consequences of these sum rules on the existence of particles beyond the standard model is studied. A comparison between different regularization schemes is also done.

If these sum rules are to be satisfied, it is shown that some simple and minimal extensions of the standard model such as the two Higgs doublet model, right handed neutrinos, mirror symmetry can not be complete extensions in their current forms. The only exception is unbroken supersymmetry and maybe broken supersymmetry. It is shown that while all considered regularization schemes give a Lorentz invariant expression for the zero point stress-energy tensor in Minkowski space, their physical interpretations are quite different.
This Letter presents measurements of correlated production of nearby jets in Pb+Pb collisions at $\sqrt{s_{\mathrm{NN}}} = 2.76$ TeV using the ATLAS detector at the Large Hadron Collider. The measurement was performed using 0.14 ${\rm nb}^{-1}$ of data recorded in 2011. The production of correlated jet pairs was quantified using the rate, $R_{\Delta R}$, of "neighbouring" jets that accompany "test" jets within a given range of angular distance, $\Delta R$, in the pseudorapidity--azimuthal angle plane. The jets were measured in the ATLAS calorimeter and were reconstructed using the anti-$k_{t}$ algorithm with radius parameters $d = 0.2$, $0.3$, and $0.4$. $R_{\Delta R}$ was measured in different Pb+Pb collision centrality bins, characterized by the total transverse energy measured in the forward calorimeters. A centrality dependence of $R_{\Delta R}$ is observed for all three jet radii with $R_{\Delta R}$ found to be lower in central collisions than in peripheral collisions. The ratios formed by the $R_{\Delta R}$ values in different centrality bins and the values in the 40-80 % centrality bin are presented.