Hengzongshu/ArticleAgent huggingface dataset:
Chronic gastritis caused by H. pylori infection, including that in «asymptomatic» patients can be considered to be an indication for H. pylori eradication therapy both as etiological treatment and opportunistic screening diagnostics for gastric cancer prevention. Indications for obligatory antihelicobacter therapy include stomach and a duodenum peptic ulcer (PU), stomach MALT-lymphoma, early gastric cancer with endoscopic resection.

Breath test with 13С-labeled urea, laboratory test for assessment of anti-H. pylori antibodies in feces, rapid urease test and serological method can be recommended for primary diagnostics of infection. Serological test is not applicable after antihelicobacter therapy. According to the bulk of regional studies clarithromycin resistance level of H. pylori strains in Russia does not exceed 15%. Obtained data indicate the absence of high metronidazole-resistance of H. pylori as well as double resistance to clarithromycin and metronidazole. Standard triple therapy including proton pump inhibitor (PPI), clarithromycin and amoxicillin is recommended as first-line treatment for H. pylori eradication. Standard triple therapy should be carried out, applying various means that increase its efficacy. Alternatively to standard triple therapy, first-line eradication treatment may include four-component bismuth tripotassium dicitratebased therapy or non-bismuth quadrotherapy which includes PPI, amoxicillin, clarithromycin and metronidazole. Quadrotherapy with bismuth tripotassium dicitrate can also be applied as a basic mode of the second line treatment at inefficiency of standard triple therapy. Alternative mode of second line eradication treatment includes PPI, levofloxacin and amoxicillin. Levofloxacinbased triple therapy prescription in the presence of strict indications should be limited to gastroenterologists. The third-line eradication treatment is adjusted individually according to the history of previous treatment modes. Eradication efficacy may be increased by prolongation of treatment up to 14 days, applicaiton of modern PPIs or increase of PPI doze, addition of bismuth tripotassium dicitrate or probiotic.

In each case of H. pylori detection it is reasonable to consider eradication therapy that is especially actual as H. pylori infection eradication is recognized as effective method of stomach cancer prevention. H. pylori eradication optimization methods can be applied both to standard and alternative modes while combination of these approaches allows to achieve the best result in a given patient.
We have refined our previously suggested scenario of generation of the cosmological baryon asymmetry through an asymmetric capture of baryons and antibaryons by primordial block hole arXiv:2009.04361. It is found that in the limit of weak interactions of hypothetical heavy baryons with the primeval plasma the effect can be strongly enhanced and the observed magnitude of the asymmetry can be obtained for a wide range of the model parameters.
Silica nanoparticles (SNPs) doped by hexanuclear molybdenum cluster complexes [{Mo6X8}L6]n (X = Cl, Br, or I; L = various inorganic or organic ligands) have been recently suggested as materials with high potential for biomedical applications due to both their outstanding photoluminescence properties and their ability to efficiently generate singlet oxygen upon photoirradiation. However, no studies were undertaken so far to prove this concept. Therefore, here we examined the potential of photoluminescent SNPs doped by {Mo6I8}4+ for applications such as bioimaging and photodynamic therapy using the human epidermoid larynx carcinoma (Hep-2) cell line as a model. Our results demonstrated both: (i) significant luminescence from cells with internalised molybdenum cluster-doped SNPs combined with the low cytotoxicity of particles in the darkness and (ii) significant cytotoxicity of the particles upon photoirradiation. Thus, this research provides strong experimental evidence for high potential of molybdenum-cluster-doped materials in biomedical applications such as optical bioimaging, biolabeling and photodynamic therapy.
In the review there highlighted contemporary concepts about the relation between the air pollution by the particulate matter (PM) and human morbidity and mortality rate due to cardiovascular diseases.

There are considered results of the short- and long-term PM impact on the human cardiovascular system in the dependence on size, origin, chemical composition, and concentration in the air. Authors performed the formalized description of the action and possible effects of PM on vascular endothelium presented as an example of systemization.

Summarizing data respective knowledge collected in the literature were used in the article as an example.
Fibre lasers are light sources that are synonymous with stability. They can give rise to highly coherent continuous-wave radiation, or a stable train of mode locked pulses with well-defined characteristics. However, they can also exhibit an exceedingly diverse range of nonlinear operational regimes spanning a multi-dimensional parameter space. The complex nature of the dynamics poses significant challenges in the theoretical and experimental studies of such systems. Here, we demonstrate how the real-time experimental methodology of spatio-temporal dynamics can be used to unambiguously identify and discern between such highly complex lasing regimes. This two-dimensional representation of laser intensity allows the identification and tracking of individual features embedded in the radiation as they make round-trip circulations inside the cavity. The salient features of this methodology are highlighted by its application to the case of Raman fibre lasers and a partially mode locked ring fibre laser operating in the normal dispersion regime.
The article presents the possibility of obtaining dairy products with stevia extract and the results of the study of organoleptic, physical and chemical properties of the finished product. Market relations require dairy producers to provide consumers with new dairy-based foods enriched with vegetable supplements. Mixed milk-based products, enriched with plant and animal products, allow you to prepare a new type of lunch with a new composition. As a natural sweetener, stevia extract gives a special sweet taste to yogurt products, as well as not only sweetens the product, but also makes it easier to absorb. This means that the stevia plant has not only tasty properties, but also easily digestible nutrients. Natural product made during the preparation of lactic acid products is a unique type of raw material with useful, highly digestible dietary properties. After all, natural milk contains a source of nutrients: immunoglobulins, hormones, growth factors, enzymes and other biologically active substances. Lactic acid product with stevia extract provides a sweet taste, a healthy type of food that does not lag behind in quality.
The most important reason for the development of the world energy market is the sustainable increase in energy production and consumption. Environmental factors and inter-fuel competition influence the structure of the market. Such factors as the emergence of new types of energy and the development of technologies for hard-to-recover reserves production also have a strong influence on the stability of the global energy industry. However, in the long-term perspective, fossil fuels will remain the most important source of energy, especially in production countries. An exception may be only some regional markets. The consumption of oil and oil products continues to have a significant share in the transport sector and, due to the forecast of leading energy organizations, it will continue to take a large share in the structure of energy consumption of transport for the next twenty years. Thus, the study of the specifics of pricing for oil and oil products is an urgent issue in the current realities. In this article, the authors evaluated the impact of main influencing factors on oil products' prices in the three largest oil-producing and exporting countries in the world: Russia, the United States, and Saudi Arabia. Based on a retrospective study of prices for petroleum products, significant factors have been identified to determine the peculiarities of the structure of prices for petroleum products in different countries. The authors have established the patterns of pricing in the analyzed market, arising due to the different levels of economic development of the countries under analysis, differences in taxation systems of the analyzed industry, and different rates of depletion of hydrocarbon reserves. The authors used the systematization and ordering of data in tabular and graphical form to identify stable patterns and trends in the pricing of petroleum products in the context of the key oil-producing countries. According to this research, we can conclude that: the main factor affecting the cost structure of gasoline in 2010-2018 in Russia is the tax burden, which currently accounts for 62.8 % of the oil product's cost; the price of petroleum products in the United States is dependent on the cost of oil production; and the prices of oil products in the domestic market of Saudi Arabia currently depend on the cost of oil production and refining costs.
The hallmarks of constitutive heterochromatin, HP1 and H3K9me2/3, assemble heterochromatin- like domains/complexes outside canonical constitutively heterochromatic territories where they regulate chromatin-templated processes. Domains are more than 100kb in size; complexes less than 100kb. They are present in the genomes of organisms ranging from fission yeast to man, with an expansion in size and number in mammals. Some of the likely functions of the domains/complexes include silencing of the donor mating type region in fission yeast, regulation of mammalian imprinted genes and the phylotypic progression during vertebrate development.

Far cis - and trans -contacts between micro-phase separated domains/complexes in mammalian nuclei contribute to the emergence of epigenetic compartmental domains (ECDs) detected in Hi-C maps. We speculate that a thermodynamic description of micro-phase separation of heterochromatin- like domains/complexes will require a gestalt shift away from the monomer as the 'unit of incompatibility', where it is the choice of monomer that determines the sign and magnitude of the Flory-Huggins parameter, χ. Instead, a more dynamic structure, the oligo-nucleosomal 'clutch', consisting of between 2 to 10 nucleosomes is both the long sought-after secondary structure of chromatin and its unit of incompatibility. Based on this assumption we present a simple theoretical framework that enables an estimation of χ for domains/complexes flanked by euchromatin and thereby an indication of their tendency to phase separate.

The degree of phase separation is specified by χN, where N is the number of 'clutches' in a domain/complex. Our approach may provide an additional tool for understanding the biophysics of the 3D genome.
Seismogeological criteria for forecasting the gas content of the Aptian-Cenomanian sediments of Western Siberia are identified and substantiated in the study based on a comprehensive interpretation of seismic data, well log data, test results and petrophysical studies results. As a reference object we use the Jubilee oil and gas condensate field, which is located in the Nadym-Pur interfluve. The field contain the unique gas deposit in the Cenomanian reservoir horizon PK1, the Albian sand layer PK18 is productive too. Based on the results of the research, seismogeological criteria for the gas-bearing forecast are formulated. If there is a giant gas deposit in Cenomanian reservoir: 1) there is a reflectors formed on gas-water contacts (GWC) in seismic cross sections, amplitude characteristics of the reflector G, which is confined to the top of the Cenomanian complex, decrease; 2) time thickness (ΔT) increases, the interval velocities (Vint) decrease and amplitude-energy characteristics of the seismic record in the Aptian-Cenomanian complex decrease. The Aptian-Albian sheet gas reservoirs are displayed in seismic cross sections a jump in amplitudes of the seismic record, forming the "bright spot" anomalies in the time sections.
DNA retrieved from a tooth discovered deep in Denisova Cave

allows us to assign it to the Denisovans

a group of archaic hominins
It is shown that flame spread rate can be high and comparable with velocities of flame propagation in the stoichiometric homogeneous gas mixture. The flame spread rate depends on velocity of oxidizer. It can either increase or decrease with arise of oxidizer velocity, depending on the oxygen content.

The flame surface is significantly distorted with increase in average flame spread rate. It is shown that the flame spread rate can be significant and comparable with the laminar burning velocity of the stoichiometric homogeneous gaseous mixture.
A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying $\tau$-lepton is presented. Two exclusive final states with either exactly one or at least two $\tau$-leptons are considered. The analysis is based on proton-proton collisions at $\sqrt{s}$ = 13 TeV corresponding to an integrated luminosity of 36.1 fb$^{-1}$ delivered by the Large Hadron Collider and recorded by the ATLAS detector in 2015 and 2016. No significant excess is observed over the Standard Model expectation. At 95% confidence level, model-independent upper limits on the cross section are set and exclusion limits are provided for two signal scenarios: a simplified model of gluino pair production with $\tau$-rich cascade decays, and a model with gauge-mediated supersymmetry breaking (GMSB). In the simplified model, gluino masses up to 2000 GeV are excluded for low values of the mass of the lightest supersymmetric particle (LSP), while LSP masses up to 1000 GeV are excluded for gluino masses around 1400 GeV. In the GMSB model, values of the supersymmetry-breaking scale are excluded below 110 TeV for all values of $\tan\beta$ in the range $2 \leq \tan\beta \leq 60$, and below 120 TeV for $\tan\beta>30$.
The article is devoted to a lexical analysis of the New Testament translation into Russian performed by an established statespersonKonstantin Pobedonostsev (1827Pobedonostsev ( -1907) ) at the beginning of the 20 th century.The lexical particularities of it have been revealed by means of its lexical comparison with the Synodal translation and the Church-Slavonic liturgical version.According to academic interpretation of the data collected the author stated that Konstantin Pobedonostsev's translationpreservesmore resemblance to the Church-Slavonic liturgical version, as there are 185 wordsinhis work, which were not found in the Synodal translation, but were used in Church-Slavonic liturgical version.The major part of the words is registered in lexicographical sources and reflects language norms of Pobedonostsev's lifetime.However, the smaller part is registered in the Russian Language National Corpus as being presented in the texts of the 1820-1920 period.The vocabulary specificity of the translation version under study lies in vast references to the Church-Slavonic liturgical version word pool.This fact is explained by stylistic preferences of the Gospel translators as well as by the target addressee image (people who are well informed about the orthodox liturgical tradition).In conclusion the author states that in his translation Konstantin Pobedonostsev never took words from the Church-Slavonic texts without prolonged meditation, the replacement cases seem to be an intentional choice of the words that were frequently used in the speech of his epoch.
Superoxide (O2-•) has been implicated in the pathogenesis of many human diseases including hypertension. Mitochondria-targeted superoxide scavenger mitoTEMPO reduces blood pressure; however, the structure–functional relationships in antihypertensive effect of mitochondria-targeted nitroxides remain unclear. The nitroxides are known to undergo bioreduction into hydroxylamine derivatives which reacts with O2-• with much lower rate. The nitroxides of pyrrolidine series (proxyls) are much more resistant to bioreduction compared to TEMPOL derivatives suggesting that mitochondria-targeted proxyls can be effective antioxidants with antihypertensive activity. In this work we have designed and studied two new pyrrolidine mitochondria targeted nitroxides: 3-[2-(triphenyphosphonio)acetamido]- and 3-[2-(triphenyphosphonio) acetamidomethyl]-2,2,5,5-tetramethylpyrrolidine-1-oxyl (mCP2) and (mCP1). These new mitochondria targeted nitroxides have 3- to 7-fold lower rate constants of the reaction with O2-• compared with mitoTEMPO; however, the cellular bioreduction of mCP1 and mCP2 was 3- and 2-fold slower. As a consequence incubation with cells afforded much higher intracellular concentration of mCP1 and mCP2 nitroxides compared to mitoTEMPO nitroxide. This has compensated for the difference in the rate of O2-• scavenging and all nitroxides similarly protected mitochondrial respiration in H2O2 treated endothelial cells. Treatment of hypertensive mice with mCP1 and mCP2 (1.4 mg/kg/day) after onset of angiotensin II-induced hypertension significantly reduced blood pressure to 133±5 mmHg and 129±6 mmHg compared to 163±5 mmHg in mice infused with angiotensin II alone. mCP1 and mCP2 reduced vascular O2-• and prevented decrease of endothelial nitric oxide production. These data indicate that resistance to bioreduction play significant role in antioxidant activity of nitroxides. Studies of nitroxide analogs such as mCP1 and mCP2 may help in optimization of chemical structure of mitochondria-targeted nitroxides for improved efficacy and pharmacokinetics of these drugs in treatment of hypertension and many other conditions including atherosclerosis, diabetes and degenerative neurological disorders in which mitochondrial oxidative stress seems to play a role.
The energy sector of Russia is one of the most potent in the world - it is the second in extraction of oil and gas, the third for total output of fuel and energy resources. While exporting nearly 45% of its total production of energy resources, Russia produces more energy per capita than most other countries - 5 times higher the global average and 3 times higher than the average level for OECD countries.

The energy sector of Siberia represents the crucial part of the country's energy sector. Over decades, the energy resources of the region massively contributed to the Russian federal budget and brought in a major part of hard currency from export trade.

In the current conditions of existing geopolitical challenges and expected global demand for energy resources, it is much more of a priority for Russia not to raise the output of fuel and energy resources but to improve the overall quality and reliability of the whole energy supply system, increase the depth of mineral fuel, including solid fuel and waste recycling.
Binary silicon-based diffractive optical element (DOE) - Gaussian-to-Square focuser (diameter of aperture is 30 mm) for the terahertz spectral range has been designed

characterized using terahertz radiation of the Novosibirsk Free Electron Laser (NovoFEL) at the wavelength of 141 mm

The preliminary experiments have demonstrated feasibility of application of binary silicon DOE for focusing of terahertz radiation into pre-given focal domain
The complex wave structure of annular gas–liquid flow with disturbance waves and liquid entrainment is a result of the evolution of high-frequency initial waves, appearing at the very inlet of the flow, prior to the hydrodynamic stabilization of liquid film. This stage of flow evolution is studied experimentally, using a shadow technique, and theoretically, using a linear stability analysis of the Orr–Sommerfeld equation in both phases. The present work is focused on the comparison of earlier results obtained in air–water downward flow with the new results obtained in upward flow and with more viscous liquids. The flow orientation affects the shape of the liquid film prior to stabilization; the initial film area is thicker but shorter in upward flow. Upward flow orientation also leads to a lower frequency and the increment of growth of initial waves. The viscosity effect is found to be weak if flow rates of both phases are the same. The model is mostly able to reproduce the qualitative trends, but the quantitative agreement is not reached. Experimental observations indicate that the liquid flow within the initial area is significantly different from the stabilized flow of gas-sheared liquid film, which is used in the model. This difference could explain the discrepancy; further development of the model should be aimed at taking into account the evolution of the velocity profile inside the liquid film during the stage of hydrodynamic stabilization.
The NP-hard problem of finding a planar support has applications in hypergraph drawing and network design. Previous algorithms for the problem assume that twins---pairs of vertices that are in precisely the same hyperedges---can safely be removed from the input hypergraph.

We prove that this assumption is generally wrong, yet that the number of twins necessary for a hypergraph to have a planar support only depends on its number of hyperedges. We give an explicit upper bound on the number of twins necessary for a hypergraph with m hyperedges to have an r-outerplanar support, which depends only on r and m.

Since all additional twins can be safely removed, we obtain a linear-time algorithm for computing r-outerplanar supports for hypergraphs with m hyperedges if m and r are constant; in other words, the problem is fixed-parameter linear-time solvable with respect to the parameters m and r.
Bombus cullumanus s. str . has attracted some of the greatest conservation concerns among bumblebees in Europe because it might now be extinct. However, there has been long-standing disagreement about whether it is conspecific with other eastern pale-banded bumblebees.

We investigate these relationships using new data from DNA (COI) barcodes.

The results support a Nearctic rufocinctus -group ( Bombus rufocinctus ) and a Palaearctic cullumanus -group, the latter with just three species: Bombus semenoviellus, Bombus unicus and B. cullumanus s. l . (including several differently coloured taxa). We conclude that, although any persisting B. cullumanus cullumanus s. str . might be a regional conservation priority within Europe, nevertheless, because the species remains common elsewhere within its range in Asia, globally a higher conservation priority should be given to B. unicus , which is genetically more distinct and appears to have a much smaller population in the Russian Far East.
The photoluminescence (PL) of the combined Ge/Si structures representing a combination of large (200–250 nm) GeSi disk-like quantum dots (nanodisks) and four-layered stacks of compact groups of smaller (30 nm) quantum dots grown in the strain field of nanodisks was studied. The multiple increase in the PL intensity was achieved by the variation of parameters of vertically aligned quantum dot groups. The experimental results were analyzed on the basis of calculations of energy spectra, electron and hole wave functions. It was found that the quantum dot arrangement in compact groups provides the effective electron localization in Δ x , y -valleys with an almost equal probability of finding an electron in the Si spacer and Ge barrier. As a result, the main channels of radiative recombination in the structures under study correspond to spatially direct optical transitions.
Journal Article Phenotype and gene frequencies in red fox populations of Russian America in 1803–1832 Get access P. M. Borodin P. M. Borodin Institute of Cytology and Genetics, USSR Academy of Science, Siberian DepartmentNovosibirsk 630090, USSR Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Heredity, Volume 72, Issue 5, September 1981, Pages 343–346, https://doi.org/10.1093/oxfordjournals.jhered.a109519 Published: 01 September 1981