Hengzongshu/ArticleAgent huggingface dataset:
We can observe self‐organization properties in various systems. However, modern networked dynamical sociotechnical systems have some features that allow for realizing the benefits of self‐organization in a wide range of systems in economic and social areas. The review examines the general principles of self‐organized systems, as well as the features of the implementation of self‐organization in sociotechnical systems. We also delve into the production systems, in which the technical component is decisive, and social networks, in which the social component dominates; we analyze models used for modeling self‐organizing networked dynamical systems. It is shown that discrete models prevail at the micro level. Furthermore, the review deals with the features of using continuous models for modeling at the macro level.
A search for physics beyond the standard model in the final state with two same-flavour leptons (electrons or muons) and two quarks produced in proton-proton collisions at sqrt(s) = 13 TeV is presented. The data were recorded by the CMS experiment at the CERN LHC and correspond to an integrated luminosity of 2.3 inverse femtobarns. The observed data are in good agreement with the standard model background prediction. The results of the measurement are interpreted in the framework of a recently proposed model in which a heavy Majorana neutrino, N(l), stems from a composite-fermion scenario. Exclusion limits are set for the first time on the mass of the heavy composite Majorana neutrino, m[N(l)], and the compositeness scale Lambda. For the case m[N(l)] = Lambda, the existence of N(e) (N(mu)) is excluded for masses up to 4.60 (4.70) TeV at 95% confidence level.
The purpose of this study was to assess the capability of recombinant angiogenin isolated from Pichia pastoris yeasts to stimulate regenerative processes in the dermis of experimental animals.

Wistar rats were administered with recombinant angiogenin intracutaneously. Morphological examination of the skin and the assessment of the proliferative activity of the epidermal cells were carried out. Additionally, cytokine production by human whole blood cells exposed to angiogenin was analyzed ex vivo.

Administration of angiogenin stimulates collagen fiber formation and angiogenesis. This stimulation is tightly associated with an increase in the number of fibroblasts, an increased numerical density of dermal blood vessels and an increased density of collagen fibers; also, it activates the proliferation of basal cells. Angiogenin induces the production of MCP, IL-8, IL-6, IL-1β, TNF-α, IL-10, TGF-β, and VEGF by blood cells. The results obtained indicate a broad spectrum of actions of recombinant angiogenin during regenerative processes in the basal layer of the dermis.
Currently, a therapeutic drug based on recombinant antibodies for the prevention and treatment of tick-borne encephalitis virus (TBEV) is developed in ICBFM SB RAS, and the chimeric antibody ch14D5 is considered as one of the key components of this drug. It was previously shown that this antibody is directed to the domain D3 of the glycoprotein E of TBEV. It was previously shown that this antibody is able to protect mice from the European subtype of TBEV, strain "Absettarov", and the presence of virus-neutralizing activity against the Far Eastern subtype of TBEV, strain 205 was also shown for this antibody. However, it remains unclear whether this antibody exhibits selectivity for different subtypes of TBEV.

The aim of this study was to investigate the effect of amino acid sequence differences of recombinant D3 domains derived from the glycoprotein E of TBEV of the Far Eastern, Siberian and European subtypes on the binding of the protective antibody ch14D5 to these proteins. Using Western blot analysis and surface plasmon resonance, it was shown that ch14D5 antibody has the highest affinity (K D = 1.7±0.5 nM) for the D3 domain of the TBEV of the "Sofjin-Ru" strain belonging to the Far Eastern subtype of the virus. At the same time, the affinity of ch14D5 antibody for similar D3 proteins derived from "Zausaev", "1528-99" and "Absettarov" strains of the Siberian and European subtypes of TBEV was noticeably lower (K D = 25±4, 300±50, 250±50 nM, respectively).

In addition, information about the spatial arrangement of amino acid residues that are different for the studied recombinant proteins indicates that the epitope recognized by the ch14D5 antibody is in close proximity to the lateral ridge of D3 domain of E glycoprotein.
The effects of asynchrony in the phenology of spring-feeding insect-defoliators and their host plants on insects’ fitness, as well as the importance of this effect for the population dynamics of outbreaking species of insects, is a widespread and well-documented phenomenon. However, the spreading of this phenomenon through the food chain, and especially those mechanisms operating this spreading, are still unclear. In this paper, we study the effect of seasonally declined leafquality (estimated in terms of phenolics and nitrogen content) on herbivore fitness, immune parameters and resistance against pathogen by using the silver birch Betula pendula—gypsy moth Lymantria dispar—nucleopolyhedrovirus as the tritrophic system. We show that a phenological mismatch induced by the delay in the emergence of gypsy moth larvae and following feeding on mature leaves has negative effects on the female pupal weight, on the rate of larval development and on the activity of phenoloxidase in the plasma of haemolymph. In addition, the larval susceptibility to exogenous nucleopolyhydrovirus infection as well as covert virus activation were both enhanced due to the phenological mismatch. The observed effects of phenological mismatch on insect-baculovirus interaction may partially explain the strong and fast fluctuations in the population dynamics of the gypsy moth that is often observed in the studied part of the defoliator area. This study also reveals some indirect mechanisms of effect related to host plant quality, which operate through the insect innate immune status and affect resistance to both exogenous and endogenous virus.
Two polymorphs of tolazamide, N-[(azepan-1-ylamino)carbonyl]-4-methylbenzenesulfonamide, a sulfonylurea anti-diabetic drug, have different densities and molecular packings. Polymorph II converts into polymorph I in the solid state on heating or via recrystallization if solvent-assisted. The effect of pressure on the two forms and the possibility of a transformation to a denser form on compression have been studied. No phase transitions have been observed in either of the forms in a pentane–isopentane mixture (when no recrystallization is possible). Polymorph II recrystallized partly into a denser polymorph I in methanol at 0.1 GPa, but the transformation stopped at an early stage. Solid state DFT calculations of the two forms as well as conformational landscape investigation in the gas phase were used to rationalize this result. The anisotropic pressure-induced strain of the two polymorphs has been compared in relation to changes in the hydrogen bond geometry and the behavior of stacking interactions.
The Tian Shan Mountains were formed in the result of the India–Eurasia collision, which leads to creation of contrast high-mountain relief and world known seismic activity. The seismic catastrophes, recorded instrumentally, have occurred to the north of the Issyk-Kul Lake region. There are also known significant earthquakes with magnitude being about 7 in western and eastern parts of the mentioned lake region. Only in the south of the Issyk-Kul depression the strong earthquakes recorded by the seismic network were not known.

Our recent study in the south of the Issyk-Kul Lake region has revealed numerous active tectonic structures related to South Issyk-Kul Fault: faults and folds, responsible for strong earthquakes' occurrence. These were historical and paleoseismic deformations which led to changes in relief: fault scarps and significant rockslides. We have also found spectacular deformations in archeological monuments. All these deformations testify the location of epicentral areas of two strong historic (about 11th and 16th (?) centuries AD) and paleoearthquakes (Holocene and Late Pleistocene). Magnitude of ancient seismic events, according to parameters of the revealed fault scarps, were Ms ≥ 7 and seismic intensity I ≥ IX. All revealed seismic deformations are located to adyrs (piedmonts) of the Terskey Ala-Too range bordered of the Issyk-Kul Lake depression in the south. Their formation is described by the model of a fault which rupture plane becomes shallower southward. This model is complicated by the presence of reverse thrusts.

Here, we should admit the existence of a single zone of South Issyk-Kul Fault which is a long-lived feature which separates the structures with the different regime of movements during the Neotectonic time. All obtained data led us to a conclusion of significant underestimation of the seismic hazard in southern Issyk-Kul Lake region.
The first data on P-T metamorphic conditions coupled with U-Pb monazite and zircon age obtained for the Neoarchean Kitoy granulite-gneiss terrane (SW Siberian Craton). Alumina gneisses of the Kitoy terrane indicate two-staged metamorphic evolution. The first stage of regional metamorphism (M1) occurred at high-amphibolite facies conditions at T ​= ​780–800 ​°C and P ​= ​8–9 ​kbar. The second stage (M2) belongs to MT-HT/LP type of metamorphism with the wide temperature interval 600–750 ​°C and pressure 2–4 ​kbar. Two age peaks were established on the basis of U-Pb monazite and zircon dating in garnet-anthophyllite gneisses. Both of them correspond to the Neoarchean age: the age of M1 falls into the interval of ca. 2489–2496 ​Ma, the age of M2 – ca. 2446–2456 ​Ma. The high-temperature metamorphism of the Kitoy block and nearly coeval granitoid magmatism can be an evidence for the Neoarchean collision in SW Siberian craton.
Fibre lasers are light sources that are synonymous with stability. They can give rise to highly coherent continuous-wave radiation, or a stable train of mode locked pulses with well-defined characteristics. However, they can also exhibit an exceedingly diverse range of nonlinear operational regimes spanning a multi-dimensional parameter space. The complex nature of the dynamics poses significant challenges in the theoretical and experimental studies of such systems.

Here, we demonstrate how the real-time experimental methodology of spatio-temporal dynamics can be used to unambiguously identify and discern between such highly complex lasing regimes. This two-dimensional representation of laser intensity allows the identification and tracking of individual features embedded in the radiation as they make round-trip circulations inside the cavity.

The salient features of this methodology are highlighted by its application to the case of Raman fibre lasers and a partially mode locked ring fibre laser operating in the normal dispersion regime.
A comparative numerical simulation of the supercritical fluid outflow on the thermodynamic equilibrium and non-equilibrium relaxation models of phase transition for different times of relaxation has been performed. The model for the fixed relaxation time based on the experimentally determined radius of liquid droplets was compared with the model of dynamically changing relaxation time, calculated by the formula (7) and depending on local parameters.

It is shown that the relaxation time varies significantly depending on the thermodynamic conditions of the two-phase medium in the course of outflowing. The application of the proposed model with dynamic relaxation time leads to qualitatively correct results.

The model can be used for both vaporization and condensation processes. It is shown that the model can be improved on the basis of processing experimental data on the distribution of the droplet sizes formed during the breaking up of the liquid jet.
Heteromorphic W and Y sex chromosomes often experience gene loss and heterochromatinization, which is frequently viewed as their “degeneration”. However, the evolutionary trajectories of the heterochromosomes are in fact more complex since they may not only lose but also acquire new sequences. Previously, we found that the heterochromatic W chromosome of a lizard Eremias velox (Lacertidae) is decondensed and thus transcriptionally active during the lampbrush stage. To determine possible sources of this transcription, we sequenced DNA from a microdissected W chromosome sample and a total female DNA sample and analyzed the results of reference-based and de novo assembly. We found a new repetitive sequence, consisting of fragments of an autosomal protein-coding gene ATF7IP2, several SINE elements, and sequences of unknown origin. This repetitive element is distributed across the whole length of the W chromosome, except the centromeric region. Since it retained only 3 out of 10 original ATF7IP2 exons, it remains unclear whether it is able to produce a protein product. Subsequent studies are required to test the presence of this element in other species of Lacertidae and possible functionality. Our results provide further evidence for the view of W and Y chromosomes as not just “degraded” copies of Z and X chromosomes but independent genomic segments in which novel genetic elements may arise.
Background Anopheles coluzzii and Anopheles arabiensis belong to the Anopheles gambiae complex and are among the major malaria vectors in sub-Saharan Africa. However, chromosome-level reference genome assemblies are still lacking for these medically important mosquito species.

Findings In this study, we produced de novo chromosome-level genome assemblies for A. coluzzii and A. arabiensis using the long-read Oxford Nanopore sequencing technology and the Hi-C scaffolding approach. We obtained 273.4 and 256.8 Mb of the total assemblies for A. coluzzii and A. arabiensis, respectively. Each assembly consists of 3 chromosome-scale scaffolds (X, 2, 3), complete mitochondrion, and unordered contigs identified as autosomal pericentromeric DNA, X pericentromeric DNA, and Y sequences. Comparison of these assemblies with the existing assemblies for these species demonstrated that we obtained improved reference-quality genomes. The new assemblies allowed us to identify genomic coordinates for the breakpoint regions of fixed and polymorphic chromosomal inversions in A. coluzzii and A. arabiensis.

Conclusion The new chromosome-level assemblies will facilitate functional and population genomic studies in A. coluzzii and A. arabiensis. The presented assembly pipeline will accelerate progress toward creating high-quality genome references for other disease vectors.
In this paper we give an example of a linear group such that its tensor square is not linear.

Also, we formulate some sufficient conditions for the linearity of non-abelian tensor products G ⊗ H and tensor squares G ⊗ G. Using these results we prove that tensor squares of some groups with one relation and some knot groups are linear.We prove that the Peiffer square of a finitely generated linear group is linear.

At the end we construct faithful linear representations for the non-abelian tensor square of a free group and free nilpotent group.
Spin-lattice relaxation times T1 of photoexcited triplets (3)C70 in glassy decalin were obtained from electron spin echo inversion recovery dependences. In the range 30-100 K, the temperature dependence of T1 was fitted by the Arrhenius law with an activation energy of 172 cm(-1). This indicates that the dominant relaxation process of (3)C70 is described by an Orbach-Aminov mechanism involving the higher triplet state t2 which lies 172 cm(-1) above the lowest triplet state t1. Chemical modification of C70 fullerene not only decreases the intrinsic triplet lifetime by about ten times but also increases T1 by several orders of magnitude. The reason for this is the presence of a low-lying excited triplet state in (3)C70 and its absence in triplet C70 derivatives. The presence of the higher triplet state in C70 is in good agreement with the previous results from phosphorescence spectroscopy.
Although American traditional medicine (ATM) has been practiced for millennia, its complex multi-target mechanisms of therapeutic action remain poorly understood. Animal models are widely used to elucidate the therapeutic effects of various ATMs, including their modulation of brain and behavior. Complementing rodent models, the zebrafish (Danio rerio) is a promising novel organism in translational neuroscience and neuropharmacology research. Here, we emphasize the growing value of zebrafish for testing neurotropic effects of ATMs and outline future directions of research in this field. We also demonstrate the developing utility of zebrafish as complementary models for probing CNS mechanisms of ATM action and their potential to treat brain disorders.
Gallotannin (or tannic acid) is a naturally occurring compound that inhibits cell growth and activity of different DNA-polymerases, including telomerase. The purpose of the present study was to gain insight into the mechanism of telomerase inhibition by gallotannin. We determined that gallotannin inhibits telomerase in vitro with an half maximal inhibitory concentrations value of 130 nM, but it does not affect telomerase complex assembly and component levels in vivo. The inhibitory activity of gallotannin against telomerase provides an additional explanation for the anti-cancer activities of this compound.
A diagnostic neutral beam injector DINA-KI60 has been developed and produced for upgraded T-15 tokamak (Kurchatov Institute, Moscow). The system will be primarily used for measurement of the ion temperature by charge-exchange recombination spectroscopy (CXRS), for magnetic field measurements via motional Stark effect (MSE) and investigation of plasma turbulence by Beam emission spectroscopy (BES).

The ion source provides 60 keV, 6 A hydrogen beam with low angular divergence less than 10 mrad. Ions are extracted from a plasma created by an arc-discharge source with cold cathode and, after accelerating and focusing, are neutralized in a gas target. The extracted beam has about 86% of full energy specie. The grids of ion optical system are spherically curved providing geometric focusing of the beam at a distance 4 m.

Diagnostic neutral beam has been successfully tested at Budker Institute of Nuclear Physics at 2 seconds pulse duration with modulation of the beam (duty ratio from 1:1 to 1:3).
This work presents new experimental data on the evolution of two-dimensional (2D) ordered arrays of microdroplets levitating over a heated liquid surface.

It was found that the average distance between the centers of the droplets in the array increases with the droplet diameter, being practically independent of the number of droplets in the array and substrate temperature.

Dimensionless correlation ratios for the distance between the droplets were obtained, which can be used to verify the theoretical models under development.
Adiabatic rapid passage using nonlinearly chirped pulses with rectangle intensity profile has been discussed.

We propose schemes of controlled-Z and controlled-not gates with ultracold neutral atoms based on deterministic phase accumulation during double adiabatic passage of the Stark-tuned F"orster resonance of Rydberg states. The effect of deterministic phase accumulation during double adiabatic passage in a two-level quantum system has been analyzed in detail. Nonlinear time dependence of the energy detuning from the F"orster resonance is used to achieve a high fidelity of population transfer between Rydberg states.

Fidelity of two-qubit gates has been studied with an example of the $90S+96S\ensuremath{\rightarrow}90P+95P$ Stark-tuned F"orster resonance in Cs Rydberg atoms.
The simplest closure models for Reynolds stress and turbulent flux are considered.

This article presents the estimation of turbulent Schmidt number in a model gas turbine combustor. Different gases are used as the model fuel while maintaining the mass flow rate.

The anisotropy of turbulent viscosity is demonstrated.
Recently Belle observed two charged bottomonium-like states, Z b (10610) and Z b (10650), that are produced in the ϒ(5S) → Z ± b π ∓ transitions and that decay to ϒ(nS)π ± (n = 1, 2, 3) and h b (mP)π ± (m = 1, 2) channels.The masses of these states are close to the B B * and B * B * thresholds, and their favored spin-parities are J P = 1 + .We review status and new results on Z b resonances, that include the observation of the Z b → B ( * ) B * decays and an evidence for the neutral member of the Z b isotriplet.All properties of the Z b states are consistent with their molecular interpretation.
The origin and geodynamic settings of the Ust’-Sema Formation and the Barangol Complex are some of the most controversial issues in the Early Paleozoic history of the Altai–Sayan Fold Belt. The Ust’-Sema Formation volcanic rocks are enriched in high-Ca clinopyroxene phenocrysts and were classified as ankaramites and diopside porphyry basalts. In this work, we first present LA-ICP-MS analyses of the clinopyroxenes, along with studies of the petrography, mineral composition, and whole-rock chemistry of the Ust’-Sema Formation and related Barangol Complex rocks. An LA-ICP-MS clinopyroxene study showed a slight depletion of light rare-earth elements (La/Yb)N = 0.1–1.0 (on average 0.4); and strong depletion of the high-field-strength elements (Zr, Hf, and Nb) and large-ion lithophile (Rb) elements. An Sr anomaly showed a positive correlation with Mg#. Major- and trace-element composition of the clinopyroxene cores show that these clinopyroxene grains were not captured from the mantle rocks as previously assumed and that the Ust’-Sema Formation and the Barangol Complex rocks were formed from magma with island arc characteristics. The increased titanium and light rare-earth element contents in the phenocryst rims from Biyka volcano suggest an active interaction of the ankaramitic magma with rocks or melts of OIB type.
For several processes at colliding beams, macroscopically large impact parameters give an essential contribution to the standard cross section. These impact parameters may be much larger than the transverse sizes of the colliding bunches. In that case, the standard calculations have to be essentially modify. The corresponding formulae were given twenty years ago. In recent paper of Baier and Katkov [17] it was claimed that the previous results about bremsstrahlung spectrum have to be revised and an additional subtraction related to the coherent contribution has to be done.

In the present paper we analyze in detail the coherent and incoherent contributions in the conditions, considered in paper [17].

In contract to above claims, we found out that under these conditions the coherent contribution is completely negligible and, therefore, there is no need to revise the previous results.