Hengzongshu/ArticleAgent huggingface dataset:
Aim. To study the prevalence of a high normal arterial blood pressure (HNABP) depending on the age-sex and ethnic characteristics of the population of Mountain Shoria and its association with the cardiovascular risk factors and genetic markers. Materials and methods. We performed a cross-sectional study of the compactly settled population in the isolated areas of Mountain Shoria (Orton and Ust-Kabyrza villages) and in urban-type settlement Sheregesh. The sample of the Shor population was 901 subjects (284 men and 617 women). As the comparison group, we examined 508 non-indigenous (newly arrived) subjects (153 men and 355 women) in the indicated villages. All the respondents underwent a general clinical laboratory and instrumental examination. Polymorphisms of genes ACE (I/D, rs 4340), АGT (c.803T>C, rs699), AGTR1 (А1166С, rs5186), ADRB1 (с.145A>G, Ser49Gly, rs1801252), ADRA2B (I/D, rs 28365031), MTHFR (c.677С>Т, Ala222Val, rs1801133) and NOS3 (VNTR, 4b/4a) were tested using polymerase chain reaction. Results. The factors associated with HNABP are analyzed in the present research. In the group of the Shors the following conditions were associated with this pathology: obesity (OR 2.03), its abdominal type (OR 1.98), genotype I/D of АСЕ gene (OR 1.80) and genotype А/С of AGTR1 gene (OR 2.03); in the non-indigenous ethnic group - obesity (OR 2.39), abdominal obesity (OR 3.17) and genotype D/D of АСЕ gene (OR 3.43). In the Shor patients with HNABP the prevalence of left ventricular myocardial hypertrophy (28.1%) and albuminuria (17.3%) appeared to be higher as compared to the non-indigenous subjects - 17.2%, (р=0.047) and 5.1% (р=0.049), respectively. Conclusion. The present study demonstrated a high prevalence of HNABP in the population of Mountain Shoria depending on ethnicity. Therefore, such patients require monitoring for an early detection of the increased blood pressure, control of risk factors, preventive examinations and dispensary observation.
Pyroxenite and nepheline-pyroxene rocks coexist with dolomite-bearing calcite marbles in Tazheran Massif in the area of Lake Baikal, Siberia, Russia. Pyroxenites occur in a continuous elongate zone between marbles and beerbachites (metamorphosed gabbro dolerites) and in 5 cm to 20 m fragments among the marbles. Pyroxene in pyroxenite is rich in calcium and alumina (5–12 wt% Al2O3) and has a fassaite composition. The Tazheran pyroxenite may originate from a mafic subvolcanic source indicated by the presence of remnant dolerite found in one pyroxenite body. This origin can be explained in terms of interaction between mafic and crust-derived carbonatitic melts, judging by the mineralogy of pyroxenite bodies and their geological relations with marbles. According to this model, the intrusion of mantle mafic melts into thick lower crust saturated with fluids caused partial melting of silicate-carbonate material and produced carbonate and carbonate-silicate melts. The fassaite-bearing pyroxenite crystallized from a silicate-carbonate melt mixture which was produced by roughly synchronous injections of mafic, pyroxenitic, and carbonate melt batches. The ascending hydrous carbonate melts entrained fragments of pyroxenite that crystallized previously at a temperature exceeding the crystallization point of carbonates. Subsequently, while the whole magmatic system was cooling down, pyroxenite became metasomatized by circulating fluids, which led to the formation of assemblages with garnet, melilite, and scapolite.
Rice growing requires highly destructive and highly invasive field management negatively affecting soil biota and its functions.

We aimed to compare taxonomic and functional trait compositions of soil macrofauna at different stages of rice cropping cycles in the three temperate rice-growing regions in Russia. Samples were collected in 2016 at four different biotopes in each region: flooded rice paddies; upland crops planted one year after flooded rice; rice paddy bunds; and relatively undisturbed seminatural control grasslands. Collected soil macrofauna were allocated to different traits according to their feeding preferences, vertical distribution, mobility and flood tolerance.

The lowest macrofaunal abundance across all regions was observed in rice paddies. Cultivation of upland crops after paddy flooding consistently decreased the abundance of resident macrofauna, but not that of mobile soil macrofauna. In the upland crops, the abundance of belowground and mobile belowground macrofauna was significantly higher than that in control grasslands. The abundance of aboveground phytophages was significantly lower in the upland crops than in control sites. Flood-associated taxa showed low colonization ability after the paddies were drained. In contrast, representatives of other traits recorded in flooded fields increased their abundance at the next stage of crop rotation, demonstrating high resilience within an entire rice-growing system, including bunds. This finding indicates a high potential of seminatural grasslands and especially bunds as sources of rapid restoration of soil macrofauna functional diversity in rice-growing agroecosystems, thus maintaining the sustainability of soil food webs in the rice paddies.
The objective : to analyze the frequency of genotypes and alleles of the rs6737848 polymorphism of the socs5 gene in patients with allergic bronchial asthma (BA) and to assess the association of this polymorphism with different levels of control over this disease.

Subjects and methods . 179 people of the Caucasian race were the subjects of the study, and they all had the confirmed diagnosis of allergic asthma. The diagnosis, severity, and level of disease control were assessed in accordance with the GINA recommendations. The comparison group included apparently healthy individuals (n = 217).

Results . The study of rs6737848 of the socs5 gene revealed statistically significant differences in the frequencies of genotypes and alleles in the group of patients with allergic asthma versus the group of healthy individuals. Among patients with allergic asthma, the frequency of the CC genotype and C allele was the highest. Carriers of the CG genotype and G allele prevailed among healthy individuals versus allergic asthma patients. Analysis of frequency distribution of genotypes and alleles of the rs6737848 polymorphism of the socs5 gene showed statistically significant predominance of the CC genotype and C allele in the sample of patients with allergic asthma that was fully or partially controlled. Conclusion . In women, the CC genotype and allele C of the socs5 gene can be considered as a genetic risk factor for the development of allergic asthma and a prognostic marker of controlled and partially controlled course of the disease. The CG genotype and G allele of the socs5 gene have a conditionally protective effect on the development of allergic asthma.
Laser scanning methods for surface geometry reconstruction have become a common tool in many areas of application due to relative simplicity, high accuracy, and versatility. Nevertheless, scanning of glossy or translucent surfaces still poses a problem for these techniques. The present work aims at assessing the applicability of the laser line scanning method for evaluation of the height profile of a waste stream on a conveyor belt, taking into account that the waste stream may contain a large number of semi-transparent objects. In particular, preliminary results of height profile measurements with regard to the laser emission wavelength for polyethylene terephthalate (PET) bottles with various degrees of transparency, common in the municipal solid wastes, are reported in the paper.
DNA N-glycosylases are key enzymes responsible for initiating the base excision repair of redox damaged bases in DNA. In our studies a thermodynamic analysis of the interaction of DNA glycosylases ...
The lecture gives an overview of the Tunka Advanced Instrument for cosmic rays and Gamma Astronomy (TAIGA) facility including historical introduction

description of existing and future setups

outreach and open data activities
The Abri du Poisson rock shelter is famous for a very realistic and detailed bas-relief of a fi sh (salmon). Representations of fi sh are quite rare in Paleolithic cave art. Another image present in this rock shelter is a negative of a hand, made in black pigment (manganese oxide). Also, the National Museum of Prehistory in Les Eyzies de Tayac (Dordogne) owns several rock blocks, painted red, with relief representations belonging to the Aurignacian levels of Abri du Poisson. Since the early 1900s, studies at that site have mostly focused on the famous representations. The 2016 fi eld study was a preliminary stage in a new project. It focused on a detailed inspection, preceding the traceological analysis of engravings and bas-reliefs. During our examination, new drawings were discovered, and photogrammetry was used for their 3D visualization. As a result, we have demonstrated that the newly discovered elements are indeed representations rather than natural lines.
Multiple scattering effects of 12 and 20 GeV electrons on 8 and 20 mm thickness carbon targets have been studied with high-resolution silicon microstrip detectors of the UA9 apparatus at the H8 line at CERN . Comparison of the scattering angle between data and GEANT4 simulation shows excellent agreement in the core of the distributions leaving some residual disagreement in the tails.
An experimental study, implicated in the revealing of the conditions for the origin for Fe3+-bearing magnesiowüstite in the lithospheric mantle, was performed using Mössbauer spectroscopy of pre-synthesized samples. Experiments were carried out using a multi-anvil high-pressure split-sphere apparatus at 6.3–7.5 GPa, in the range of 1100–1650 °C in carbonate-metal, carbonate–oxide-metal, carbonate-oxide, carbide-oxide and carbonate–metal- sulphur systems. In three experimental series, oxygen fugacity gradient in the samples was created, which enabled the study of the processes of magnesiowüstite formation under oxidizing and reducing conditions (ΔlogfO2 (FMQ) values from −1 to −5). It was established that Fe3+-bearing magnesiowüstite can form both in assemblage with oxidized phases, such as carbonate or with reduced ones—metal, carbides, sulphides, graphite and diamond. According to the Mössbauer spectroscopy, the composition of synthesized magnesiowüstite varied within a range of Fe3+/ΣFe values from 0 to 0.3, with IV and VI coordination of Fe3+ depending on P, T, fO2, x-parameters. It was established that Fe3+-bearing magnesiowüstite formation processes under upper mantle P,T-conditions include redox reactions, with magnesiowüstite being (1) reductant or (2) product of interaction, (3) crystallization processes of magnesiowüstite from an oxidized melt, where magnesiowüstite acts as a sink for ferric iron and (4) iron disproportionation.
Combined power of 59Co Internal Field nuclear magnetic resonance (IF NMR) and ferromagnetic resonance (FMR) allows studying structure and morphology of metallic Co nanoparticles.
In the paper [13], for an arbitrary virtual link [Formula: see text], three groups [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] were defined. In the present paper, these groups for the virtual trefoil are investigated. The structure of these groups are found out and the fact that some of them are not isomorphic to each other is proved. Also, we prove that [Formula: see text] distinguishes the Kishino knot from the trivial knot. The fact that these groups have the lower central series which does not stabilize on the second term is noted. Hence, we have a possibility to study these groups using quotients by terms of the lower central series and to construct representations of these groups in rings of formal power series. It allows to construct an invariants for virtual knots.
A new scheme of wave fields modelling from point sources in a homogeneous isotropic elastic medium is developed. To set the source the developed technique is based on the use of additional components of the finite-difference grid and the use of all the stress tensor components in the nodes. The results of the scheme employment in the two-dimensional homogeneous isotropic medium are presented; they demonstrate the numerical solutions' improvement for the source being under consideration in the article.
[Background/Aims] One of the strategies for creating new pharmacologically active compounds is the use of a central scaffold and the addition of various substituents to it. The diazabicyclic molecule bispidine represents a promising basis for chemical modifications and synthesis of compounds with diverse biological activities. In this work, the actoprotective effect of N, N-disubstituted bispidine derivatives containing monoterpene substituents is shown for the first time. The present work evaluated the actoprotective activity, locomotor and anxiety-like behavior in mice, and the effect on the cholinergic system in the central nervous system. Bromantane was used as a reference drug. [Results] The results showed that compounds combining bispidine scaffold and monoterpenoid fragments exhibit actoprotective effect in tests on a treadmill and swim with a load of 10% of body mass, increasing the duration of physical work. In the "Open field" test, which determines the locomotor and anxiety-like behavior in mice, it was found that some disubstituted derivatives significantly increased the distance and residence time of animals in the center of the open field compared to intact controls, which may indicate a stimulating effect on the central nervous system and a possible anxiolytic effect. As a result, compounds combining fragments of a monoterpenoid and 3,7-diazabicyclo[3.3.1]nonane (bispidine) core exhibit actoprotective activity, acting on various neurotransmitter systems. This work was supported by RFBR Grant 18-03-00437.
The need for blood circulation support systems in the treatment of chronic heart failure is constantly increasing as 20% of patients on the waiting list die every year. Despite the great need for mechanical heart support systems the use of available systems is limited by the high cost. Therefore, further research in the field of circulatory support systems is appropriate taking into account medical and technical requirements. One of the new research areas is viscous friction disk pumps for transporting liquids based on the Tesla pump principle. The experimental model of LVAD disk pump is developed. Analytical dependencies are obtained to optimize the hydraulic parameters of the pump. On their basis, the experimental model of LVAD disk pump was designed and created. The results of analytical and experimental studies of such a pump are presented.
The process e(+)e(-)-->mu(+)mu(-) has been studied by the SND detector at the VEPP-2M e(+)e(-) collider in the phi(1020)-resonance energy region.

The measured effective phi meson leptonic branching ratio B(phi-->l(+)l(-)) identical with square root of B(phi-->e(+)e(-))B(phi-->mu(+)mu(-))] = (2.89 +/- 0.10 +/- 0.06) x 10(-4) agrees well with the Particle Data Group value B(phi-->e(+)e(-)) = (2.91 +/- 0.07) x 10(-4), confirming mu-e universality.

Without additional assumption of mu-e universality the branching ratio B(phi-->mu(+)mu(-)) = (2.87 +/- 0.20 +/- 0.14) x 10(-4) was obtained.
We investigate a single-particle density of states (DOS) in strongly disordered two-dimensional high dielectric permittivity systems with logarithmic Coulomb interaction between particles. We derive self-consistent DOS at zero temperature and show that it is appreciably suppressed as compared to the DOS expected from the Efros-Shklovskii approach. We carry out zero- and finite-temperature Monte Carlo numerical studies of the DOS and find the perfect agreement between the numerical and analytical results at zero temperature, observing, in particular, a hardening of the Coulomb gap with the increasing electrostatic screening length. At finite temperatures, we reveal a striking scaling of the DOS as a function of energy normalized to the temperature of the system.
В докладе рассказываете об опыте прогнозирования биржевых котировок с применением аппарата нейронных сетей.

Предлагается гибридная архитектура нейросети на основе самоорганизующейся карты Кохонена и многослойного персептрона, а также авторская идея иерархической структуры самоорганизующегося слоя и алгоритм справедливого обучения кластеров.

Рассматриваются различные виды зависимостей в данных и приводится пример обучения подобной архитектуры на функции типа лунная поверхность . Report contains authors experience in predicting exchange rates time series with neural networks. The hybrid architecture suggested, based on Self-Organizing Maps (SOM) and Multi-Layer Perceptron (MLP) as well as authors method of building hierarchical SOM structure with equitable teaching algorithm. Different types of data dependencies discussed, and the example of adjusted model shown.
Experimental data that prove the existence of the zygotic combinatorial process occurring in an embryogenesis-entering zygote are presented in the paper. The zygotic combinatorial process is found when analyzing F1 hybrid plants obtained from crossing homozygous forms different, minimum, in two marker enzymes, and it is found in that hybrid plant which, with one marker enzyme heterozygous spectrum, has a homozygous spectrum of the other. The zygotic combinatorial process leads to F1 hybrids uniformity aberration. The zygotic combinatory process revealed in the study is supposed to be conditioned by chromosome polyteny in mother plant cells and diminution of chromatin excess from the embryogenesisentering zygote. An obligatory condition for combinatorial process is the presence of free exchange of chromatides among homological chromosomes in an embryogenesis-entering cell, i.e. the presence of crossing-over analogous to the one proceeding at meiosis.
Continental-scale estimates of vegetation cover, including land-surface properties and biogeographic trends, reflect the response of plant species to climate change over the past millennia. These estimates can help assess the effectiveness of simulations of climate change using forward and inverse modelling approaches. With the advent of transient and contiguous time-slice palaeoclimate simulations, vegetation datasets with similar temporal qualities are desirable.

We collated fossil pollen records for the period 21,000–0 cal yr BP (kyr cal BP; calibrated ages) for Europe and Asia north of 40°N, using extant databases and new data; we filtered records for adequate dating and sorted the nomenclature to conform to a consistent yet extensive taxon list. From this database we extracted pollen spectra representing 1000-year time-slices from 21 kyr cal BP to present and used the biomization approach to define the most likely vegetation biome represented. Biomes were mapped for the 22 time slices, and key plant functional types (PFTs, the constituents of the biomes) were tracked though time. An error matrix and index of topographic complexity clearly showed that the accuracy of pollen-based biome assignments (when compared with modern vegetation) was negatively correlated with topographic complexity, but modern vegetation was nevertheless effectively mapped by the pollen, despite moderate levels of misclassification for most biomes.

The pattern at 21 ka is of herb-dominated biomes across the whole region. From the onset of deglaciation (17–18 kyr cal BP), some sites in Europe record forest biomes, particularly the south, and the proportion of forest biomes gradually increases with time through 14 kyr cal BP. During the same period, forest biomes and steppe or tundra biomes are intermixed across the central Asian mountains, and forest biomes occur in coastal Pacific areas. These forest biome occurrences, plus a record of dated plant macrofossils, indicate that some tree populations existed in southern and Eastern Europe and central and far-eastern Eurasia. PFT composition of the herbaceous biomes emphasises the significant contribution of diverse forbs to treeless vegetation, a feature often obscured in pollen records. An increase in moisture ca. 14 kyr cal BP is suggested by a shift to woody biomes and an increase in sites recording initialization and development of lakes and peat deposits, particularly in the European portion of the region. Deforestation of Western Europe, presumably related to agricultural expansion, is clearly visible in the most recent two millennia.
The region of high turbulent kinetic energy is located inside the recirculation zone behind the bluff-body where the low-frequency motion is known to occur which is detected with energy spectra.

Using high-order spectral element method and large eddy simulations we study a turbulent annular jet at the Reynolds number of 8900, based on the bulk velocity in the annular channel and its half-width. Further analysis includes the azimuthal Fourier and Proper orthogonal decomposition (POD).

It is shown that the main eigenmodes with low azimuthal wavenumbers m rotate around the symmetry axis in both directions providing the explanation for the precessing motion of the recirculating zone.
Parahydrogen-induced polarization of 13C nuclei by side-arm hydrogenation (PHIP-SAH) for [1-13C]acetate and [1-13C]pyruvate esters with application of PH-INEPT-type pulse sequences for 1H to 13C polarization transfer is reported, and its efficiency is compared with that of polarization transfer based on magnetic field cycling (MFC). The pulse-sequence transfer approach may have its merits in some applications because the entire hyperpolarization procedure is implemented directly in an NMR or MRI instrument, whereas MFC requires a controlled field variation at low magnetic fields.

Optimization of the PH-INEPT-type transfer sequences resulted in 13C polarization values of 0.66 ± 0.04% and 0.19 ± 0.02% for allyl [1-13C]pyruvate and ethyl [1-13C]acetate, respectively, which is lower than the corresponding polarization levels obtained with MFC for 1H to 13C polarization transfer (3.95 ± 0.05% and 0.65 ± 0.05% for allyl [1-13C]pyruvate and ethyl [1-13C]acetate, respectively).

Nevertheless, a significant 13C NMR signal enhancement with respect to thermal polarization allowed us to perform 13C MR imaging of both biologically relevant hyperpolarized molecules which can be used to produce useful contrast agents for the in vivo imaging applications.
We calculate in the next-to-leading approximation the nonforward gluon impact factors for an arbitrary color state in the t channel. In the case of the octet state we check the so-called ``second bootstrap condition'' for gluon Reggeization in QCD, using the integral representation for the impact factors. The condition is satisfied in the general case of an arbitrary space-time dimension and massive quark flavors for both helicity conserving and nonconserving parts.