Hengzongshu/ArticleAgent huggingface dataset:
Deltamethrin (DM) is a α- cyano pyrethroid insecticide used extensively in pest control. Although initially thought to be least toxic, a number of recent reports showed its toxicity in mammalian and non-mammalian laboratory and wildlife animal species. The present study, carried out in male rats, is a contribution to explore some mechanisms underlying DM toxicity. The aim of the present research was to investigate the effect of different subcutaneous treatments with DM (2 ppm for 30 days, 20 ppm for 45 days and 200 ppm for 60 days) on testes histopathology, sex hormones and oxidative stress from male rats. Our study mentioned an hypospermatogenesis within the testes accompanied by some apoptotic figures in particular cell fragments into the seminiferous tubules (ST)' lumen. The results obtained show that follicule-stimulating hormone (FSH), luteinizing hormone (LH) and testosterone can be differently influenced in rats. In fact, findings of the present investigation mention a significant decrease (p ≤ 0.05) of FSH, LH and testosterone at the highest DM dose. Whereas a significant reduction of FSH was noticed after 45 days of treatment. The assessment of oxidative stress by malondialdehyde (MDA) measurements in plasma revealed a significant increase of this parameter after 30 days, 45 days or 60 days. In conclusion the study shows that subcutaneous DM treatment produces an arrest of spermatogenesis, a significant disharmony in sex hormones and MDA levels in rats that is related to dose, length of treatment and to the lipid peroxidation which may be one of the molecular mechanisms involved in DM-induced gonads toxicity.
We present a new 3‐D anisotropic seismic model for the crust and upper mantle beneath Hokkaido (Japan) based on tomographic inversion of P and S arrival times from a regional seismic database. The P model is parameterized with three parameters at each point that describe the azimuthal anisotropy; the S model is represented isotropically. The isotropic P and S velocity anomalies match nearly perfectly. In the crust, they show a prominent linear anomaly in central Hokkaido along the Kamuikotan and Hidaka Belts, which represents the area of eastward underthrusting of the Japan Block underneath the Kuril fore arc. We interpret the high‐velocity anomaly beneath the Hidaka zone as being delaminated mafic crust and entrained mantle lithosphere, which developed due to crustal shortening in the collision zone. One of our vertical sections shows a very unusual configuration for a subduction zone: a low‐velocity slab is overlain by a high‐velocity body in the mantle wedge. We propose that the high‐velocity delaminated material sinking along the slab surface prevents the escape of fluids and melts from the upper part of the slab, where they are generated due to phase transitions. As a result, a large portion of the fluids is entrained downward and lowers the seismic velocities in the slab. The azimuthal anisotropy in the crust clearly corresponds to the major tectonic units and delineates the major suture zones. In the mantle, the anisotropy has a fan‐shaped configuration and most likely represents the deviating of flows starting in southern Hokkaido and splitting into three directions. The western and eastern flows proceed toward the two volcanic groups on Hokkaido, and they may carry with them additional material to trigger the characteristic caldera‐forming eruptions in these groups.
This reaction was previously studied by Holvik and Olsen [Phys. Rev. D 35, 2124 (1987)] on the basis of a bremsstrahlung mechanism where OM is produced by only one virtual photon.

In the present paper, we consider a competing three-photon mechanism where the production of OM results from the collision of a photon generated by the electron with two photons emitted by the nucleus. We derive the corresponding energy spectrum and production rate of OM

and show that the three-photon mechanism is the dominant one for a heavy atom target.
In this review we integrate results of long term experimental study on ant “language” and intelligence which were fully based on fundamental ideas of Information Theory, such as the Shannon entropy, the Kolmogorov complexity, and the Shannon’s equation connecting the length of a message (l) and its frequency (p), i.e., l = –log p for rational communication systems. This approach enabled us to obtain the following important results on ants’ communication and intelligence: (i) to reveal “distant homing” in ants, that is, their ability to transfer information about remote events; (ii) to estimate the rate of information transmission; (iii) to reveal that ants are able to grasp regularities and to use them for “compression” of information; (iv) to reveal that ants are able to transfer to each other the information about the number of objects; (v) to discover that ants can add and subtract small numbers. The obtained results show that information theory is not only excellent mathematical theory, but many of its results may be considered as Nature laws.
Accurate recognition of regulatory elements in promoters is an essential prerequisite for understanding the mechanisms of gene regulation at the level of transcription. Composite regulatory elements represent a particular type of such transcriptional regulatory elements consisting of pairs of individual DNA motifs. In contrast to the present approach, most available recognition techniques are based purely on statistical evaluation of the occurrence of single motifs. Such methods are limited in application, since the accuracy of recognition is greatly dependent on the size and quality of the sequence dataset. Methods that exploit available knowledge and have broad applicability are evidently needed.

We developed a novel method to identify composite regulatory elements in promoters using a library of known examples. In depth investigation of regularities encoded in known composite elements allowed us to introduce a new characteristic measure and to improve the specificity compared with other methods. Tests on an established benchmark and real genomic data show that our method outperforms other available methods based either on known examples or statistical evaluations. In addition to better recognition, a practical advantage of this method is first the ability to detect a high number of different types of composite elements, and second direct biological interpretation of the identified results. The program is available at http://gnaweb.helmholtz-hzi.de/cgi-bin/MCatch/MatrixCatch.pl and includes an option to extend the provided library by user supplied data.

The novel algorithm for the identification of composite regulatory elements presented in this paper was proved to be superior to existing methods. Its application to tissue specific promoters identified several highly specific composite elements with relevance to their biological function. This approach together with other methods will further advance the understanding of transcriptional regulation of genes.
The entropy production scenarios due to the electroweak phase transition (EWPT) in the framework of the minimal extension of standard model, namely the two Higgs doublet model (2HDM), are revisited.

Intense parameter scanning was done with the help of BSMPT, a C++ package. We perform numerical calculations in order to calculate the entropy production with numerous benchmark points.

The possibility of first order phase transition is discussed.
For a long time, interest in multimode (MM) optical fibers has remained limited, owing to the poor quality of laser beams emerging at their output. A typical indicator of beam quality is inversely proportional to the number of excited modes.

However, recent intensive research of nonlinear propagation effects, involving high-power laser beams in MM graded-index (GRIN) fibers, has led to the discovery of previously unexpected phenomena, such as the Kerr-activated self-cleaning of a beam [1] . The manifestation of self-cleaning is that most of the beam energy flows into the fundamental mode of the fiber. This process is accompanied by a redistribution of energy towards higher-order modes [2] . Increasing the fundamental mode energy leads to improving the output beam quality. The standard method to determine the beam quality is to measure the M2-parameter (m-squared). This parameter measures the divergence of the beam with respect to the Gaussian beam.

However, since self-cleaning involves a nonlinear redistribution of energy carried by a large number of fiber modes, this approach is not entirely correct, and a full mode decomposition (MD) of the output beam appears to be a much more informative method.
Aim . To determine the levels of psychosocial factors (PSF) of the cardiovascular risk (CVR) in young men and women in gender dimension (on the model of Tyumen). Material and methods . An epidemiological cross-sectional study was conducted on a representative sample of the Tyumen population among men (n=1000, response 85,0%) and women (n=1000, response 70,3%) of 25-64 years old; 25,0% in each life decade. Data were obtained from young people aged 25-34 and 35-44 years old compared with a standardized age value (25-64 years). The PSF examination was carried out according to the algorithms of the WHO MONICA-Psychosocial Program. Results . Among young open urban population, the prevalence of moderate levels of depression and life exhaustion, a high level of hostility, moderate level of personal anxiety in men and a high level of personal anxiety in women was observed. In men of 25-34 years, compared with the general population values, the highest prevalence of the personal anxiety moderate level and hostility high level was revealed. There were high personal anxiety, depression and hostility levels among young women. In the gender dimension, young women were characterized by a significantly higher prevalence of high levels of CVR PSF: personal anxiety, depression, hostility, life exhaustion, moderate levels of life exhaustion, men —moderate levels of personal anxiety and hostility. Conclusion . The data obtained should be useful for formation of preventive cardiology programs on the basis of PSF assessing, starting from a young age.
Despite the huge amount of works devoted to the study of mitotic division, there is still a lot of unclear in its mechanisms. For example, insufficient attention has been paid to the processes of cell division in plant forms of different ploidy levels. The literature contains only fragmentary data on haploids in lower plants. This does not allow making any generalizations regarding mitosis in haploids of higher plants. This article presents the results of a cytological study of mitotically dividing cells of haploid maize plants. The article demonstrates the effectiveness of the well-known Chase method, based on the use of genetic markers and the ig mutation (indeterminate gametophyte) for obtaining and detecting haploids. An effective modification of a simple method of acetocarmine staining of cytological preparations is described. An essential result obtained is, in our opinion, the detection of a very brief moment in the state of chromosomes in a dividing cell of a haploid maize plant. This moment is characterized by the fact that the chromatids have already separated and turned into independent chromosomes, but have not yet begun their movement under the action of kinetochore microtubules. It is this feature that made it possible to designate this state as late prophase – early prometaphase of mitosis. An equally important feature of the detected moment is the unusual ordered arrangement of chromosomes, which lie parallel to each other close to each other along their entire length with the centromeres located on one line, which can be considered the equator of the fission spindle. The revealed fact allows us to assume that an essential role in the formation of such an arrangement of chromosomes is played by the bond of chromosomes with the equator of the nuclear membrane and their subsequent connection with the equator of the fission spindle.
The review presents recommendations for pre-hospital management of traumatic haemorrhagic shock (PHMTHS), details of its performance, criteria for evaluation of efficacy and results of application.

The main principles of PHMTHS developed during military activity of armed forces of the USA and their allies in Iraq and Afghanistan were: controlled hypotension, early infusion of tranexamic acid and the priority of blood loss replacement via transfusion.

PHMTHS performed according to the stated principles leads to a significant decrease in the number of lethal outcome cases. This offers prospects for application of similar tactics of pre-hospital management in civilian medicine.
In this work we present the preliminary results of numerical simulations of detonation wave propagation in a plane channel conducted with an in-home code solving the chemically reacting Euler equations on supercomputers with GPUs.

The simulations are performed with four detailed chemical kinetics mechanisms (ONERA, Deiterding, modified Jachimowski, Peterson and Hanson models). The latter model includes a pressure-dependent reaction. The 1D and 2D Euler equations are solved for a hydrogen/oxygen mixture using high-order shock-capturing TVD schemes and a finite-rate chemistry solver.

The sizes of detonation cells obtained with different models are compared.
metasurfaces comprised by spiral-disk-shaped metallic elements patterned on polypropylene substrates, which exhibited localized surface plasmon resonances in the low-frequency region of the terahertz (THz) spectrum (0.2–0.5 THz)

Optimal designs of spiral disks with C-shaped resonators placed near the disks were determined and fabricated. The experimentally measured transmittance spectra of the samples coated with very thin photoresistive layers (d ~ 10−4–10−3 λ) showed good agreement with the simulations. The resonance frequency shift Δf increases with increasing d, while saturating near d = 50 µm

The narrow-band magnetic dark modes excited on symmetrical spiral disks with a 90° C-resonator demonstrated very high figure of merit (FOM) values reaching 1670 (RIU·mm)−1 at 0.3 μm thick analyte. The hybrid high order resonances excited on asymmetrical densely packed spiral disks showed about two times larger FOM values (up to 2950 (RIU·mm)−1) compared to symmetrical distantly spaced spirals that resembled the best FOM results found in the literature for metasurfaces fabricated with a similar technique. The demonstrated high sensing performance of spiral disks is evaluated to be promising for bio-sensing applications in the THz range
The TAIGA-experiment aims to implement a hybrid detection technique of Extensive Air Showers(EAS) at TeV to PeV energies, combining the wide angle Cherenkov timing array HiSCORE withImaging Air Cherenkov Telescopes (IACTs). The detector currently consists of 89 HiSCOREstations and two IACTs, distributed over an area of about 1 km². Our goal is to introduce a newreconstruction technique, combining the good angular and shower core resolution of HiSCOREwith the gamma-hadron separation power of the imaging telescopes. With the second IACT inoperation, three different event types can be explored: IACT stereo, full hybrid (IACT stereo +stations) and mono hybrid (IACT mono + HiSCORE), the latter being the operational goal ofTAIGA. The status of the development of the full hybrid reconstruction and its verification usingreal data and simulation are presented.
We present a search for seven lepton-flavor-violating neutral charm meson decays of the type D0→X0e±μ∓, where X0 represents a π0, K0S, ¯K*0, ρ0, ϕ, ω, or η meson.

The analysis is based on 468 fb−1 of e+e− annihilation data collected at or close to the Υ(4S) resonance with the BABAR detector at the SLAC National Accelerator Laboratory.

No significant signals are observed, and we establish 90% confidence level upper limits on the branching fractions in the range (5.0−22.5)×10−7. The limits are between 1 and 2 orders of magnitude more stringent than previous measurements.
A new scheme for accelerating positively charged particles in a plasma-wakefield accelerator is proposed. If the proton drive beam propagates in a hollow plasma channel, and the beam radius is of order of the channel width, the space charge force of the driver causes charge separation at the channel wall, which helps to focus the positively charged witness bunch propagating along the beam axis. In the channel, the acceleration buckets for positively charged particles are much larger than in the blowout regime of the uniform plasma, and stable acceleration over long distances is possible. In addition, phasing of the witness with respect to the wave can be tuned by changing the radius of the channel to ensure the acceleration is optimal. Two-dimensional simulations suggest that, for proton drivers likely available in future, positively charged particles can be stably accelerated over 1 km with the average acceleration gradient of $1.3\text{ }\text{ }\mathrm{GeV}/\mathrm{m}$.
The results of a numerical study of the development of periodic pulsations in a supersonic boundary layer on a flat plate are presented at a Mach number of 2.5 and a unit Reynolds number of 8×10 6 m –1 .

Using the software complex ANSYS, the complete Navier-Stokes equations were solved. Periodic mass flow disturbances with a frequency of 20 kHz were introduced into the boundary layer through a small-diameter hole on the surface of the model. Downstream the profiles of the longitudinal mass flow pulsations were recorded, and spectral analysis of the data was carried out.

The main characteristics of the development of unstable disturbances in both physical and wave spaces are obtained.
We propose a combined computational approach based on the multi-phase-field and the lattice Boltzmann method for the motion of solid particles under the action of capillary forces. The accuracy of the method is analyzed by comparison with the analytic solutions for the motion of two parallel plates of finite extension connected by a capillary bridge. The method is then used to investigate the dynamics of multiple spherical solid bodies connected via capillary bridges. The amount of liquid connecting the spheres is varied, and the influence of the resulting liquid-morphology on their dynamics is investigated. It is shown that the method is suitable for a study of liquid-phase sintering which includes both phase transformation and capillary driven rigid body motion.
Terahertz surface plasmon resonance (SPR) sensors have been regarded as a promising technology in biomedicine due to their real-time, label-free, and ultrasensitive monitoring features. Different authors have suggested a lot of SPR sensors, including those based on 2D and 3D metamaterials, subwavelength gratings, graphene, and graphene nanotube, as well as others. However, one of the traditional approaches to realize high sensitivity SPR sensors based on metal diffraction gratings has been studied poorly in the terahertz frequency range. In this article, a linear metal rectangular diffraction grating with high aspect ratio is studied. The influence of the grating structure parameters on the sensor sensitivity is simulated. Effects arising from different ratios of depth and width were discovered and explained. The results show that the sensitivity can be increased to 2.26 THz/RIU when the refractive index range of the gas to measure is between 1 and 1.002 with the resolution 5×10-5 RIU.
A Schur ring over a finite group is said to be decomposable if it is the generalized wreath product of Schur rings over smaller groups. In this paper we establish a sufficient condition for a decomposable Schur ring over the direct product of elementary abelian groups to be a CI-Schur ring. By using this condition we offer short proofs for some known results on the CI-property for decomposable Schur rings over an elementary abelian group of rank at most 5.
Fossil record of Earth describing the last 500 million years is characterized by evolution discontinuity as well as recurring global extinctions of some species and their replacement by new types, the causes of which are still debate.

We developed a model of evolutionary self-development of a large ecosystem. This model of biota evolution based on the universal laws of living systems functioning: reproduction, dependence of reproduction efficiency and mortality on biota density, mutational variability in the process of reproduction and selection of the most adapted individuals.

We have shown that global extinctions and phases of rapid growth and biodiversity stasis can be a reflection of the emergence of bistability in a self-organizing system, which is the Earth’s biota. Bistability was found to be characteristic only for ecosystems with predominant sexual reproduction. The reason for the transition from one state to another is the selection of the most adapted individuals. That is, we explain the characteristics of the Earth’s fossil record during the last 500 million years by the internal laws of Earth’s ecosystem functioning, which appeared at a certain stage of evolution as a result of the emergence of life forms with an increased adaptive diversification associated with sexual dimorphism.
Авторепрезентация героя рудинского типа в поэтике прозы А. П. Чехова середины 1880 -1890-х годов
Dicarboxylic acids, HOOC-(CH2) n -COOH, are interesting compounds from the structural point of view [1].A very long one-dimensional chain can be obtained through hydrogen bond formation at both ends of the molecule.These compounds configure layered structures in the solid state, as well as most of the polymorphic phases of long-chain compounds, such as n-alkanes, n-alcohols, and n-fatty acids.Dicarboxylic acids exhibit interesting thermal properties and a high enthalpy of melting that make them potential candidates for their use in the field of thermal protection and energy storage.Dimorphism was prevalent in odd carbon members of dicarboxylic acids while one form is only present for even members: α form P2 1 /c with Z=4 and β form C2/c with Z=4.High-quality x-ray powder diffraction analyses of pentadecanedioic acid (C 15 H 28 O 4 ) have been carried as a function of temperature.A new form, called γ has been observed just before melting: γ form C2/c with Z=4 at 383K.The packing arrangement of the carboxyl groups at both end of the chain is different in the three forms.From the structural point of view for γ form the distance interlayer is intermediate between α and β distances.Crystal structure of the pentadecanedioic acid is presented.The carboxyl's group in α form shows two different angles with middle plain of the chain.The packing arrangement of α and γ forms are radically different even if the molecular conformation are cis in both cases.A reversible transition from β form to γ form was observed before melting.Slurry experiments indicate that β is the most stable form at room temperature.