Hengzongshu/ArticleAgent huggingface dataset:
Быстрая сортировка с двумя опорными элементами является одной из наиболее эффективных в базисном наборе алгоритмов сортировки стандартной библиотеки Java Development Kit (JDK) для языка Java.

Beckert B. и др.построили спецификацию этого алгоритма на языке JML и успешно провели дедуктивную верификацию в системе KeY
A vacuum-insulated tandem accelerator was used to observe in situ blistering during 2-MeV proton irradiation of metallic samples to a fluence of up to 6.7 × 1020 cm−2.

Samples consisting of copper of different purity, tantalum and tantalum-copper compounds were placed on the proton beam path and forced to cool. The surface state of the samples was observed using a charge-coupled device camera with a remote microscope. Thermistors, a pyrometer and an infrared camera were applied to measure the temperature of the samples during irradiation. After irradiation, the samples were analyzed on an X-ray diffractometer, laser and electron microscopes.

The present study describes the experiment, presents the results obtained and notes their relevance and significance in the development of a lithium target for an accelerator-based neutron source, for use in boron neutron capture therapy of cancer.
The article examines a significant lexical layer of the Stishnoy Prologue which is the vocabulary of artifact names (i. e. ‘objects made by man’). The revealed vocabulary includes 23 thematic groups. Intra-word and inter-word paradigmatic relations were analyzed in the group of artifact nominations. The purpose of our study is a comprehensive analysis of the names of artifacts in the Stishnoy Prologue. An analysis of the functional features of the artifact names showed that the genre of the text presented in the Stishnoy Prologue defines the frequency of use of the analyzed lex emes. Analysis of the artifact names in the Stishnoy Prologue reveals that the group of such lexemes is quite diverse and includes not only names of objects of worship and church life and instruments of torture, but also units denoting everyday vocabulary such as names of jewelry, objects of crafts, etc. The frequency of use of such lexemes in the text of the manuscript and their semantic connections within and outside of the group indicate that the units belong to the active vocabulary of the Church Slavonic language of the 15th century.
Nonlinearity plays a critical role in the intra-cavity dynamics of high-pulse energy fiber lasers. Management of the intra-cavity nonlinear dynamics is the key to increase the output pulse energy in such laser systems.

Here, we examine the impact of the order of the intra-cavity elements on the energy of generated pulses in the all-normal dispersion mode-locked ring fiber laser cavity. In mathematical terms, the nonlinear light dynamics in resonator makes operators corresponding to the action of laser elements (active and passive fiber, out-coupler, saturable absorber) non-commuting and the order of their appearance in a cavity important.

For the simple design of all-normal dispersion ring fiber laser with varying cavity length, we found the order of the cavity elements, leading to maximum output pulse energy.
The significant progress observed in the field of artificial economy opens up new possibilities for modeling economic growth. Agent-based models (ABM) allow leaving the concept of a representative agent in the past and linking investment decisions of economic agents at the micro level with long-term macroeconomic growth. Modern ABMs offer new algorithms for modeling expectations, agent interaction, technical progress, pricing, and production planning.

Our article analyzes the current state of modeling investment in fixed assets in operating macroeconomic ABMs. The subject of the review is the families of models Eurace, CATS, KS, Jamel, Lagom. The authors also present the investment block of the agent-based multiregional input-output model (ABMIOM) being developed.

Comparative analysis demonstrates that modern ABMs, as a rule, implement the principle of stock-flow consistency. Modeling the investment process requires detailing the commodity nomenclature, so that the initially adopted two-sector division into investment and consumer goods is replaced by more detailed structures, which gives rise to the problem of accounting for inter-sectoral relations in production and consumption. The Leontief production function copes with this problem, which is confirmed by its widespread use in ABM. The size of firms' investments is often derived from the need to expand capacity in accordance with the current production plan, so that planning turns out to be myopic, and long-term aspects in ABM are still largely unrealized. Nevertheless, already now ABMs reproduce many phenomena associated with the economic cycle. The developed ABMIOM provides horizontal consistency of cash flows between agents and analysis of results using input-output tables. ABMIOM represents a step forward in reflecting intersectoral and interregional flows. The model reproduces the growth and contraction of the economy as a result of independent investment decisions of individual firms and households, which is reflected in the sectoral and spatial structure of the economy. Further development of ABMIOM is associated with the modeling of savings, intrafirm finance, money market, innovation and technical progress.
An in situX-ray powder diffraction study has shown that cubic modification of (NH4)2SiF6 (cryptohalite) at 0.2-0.3 GPa transforms irreversibly into a trigonal polymorph with cell parameters a = 5.78 A and c = 4.78 A, presumably the previously known bararite, space group P-3m1. The choice of a pressuretransmitting liquid (methanol/ethanol/water mixture or poly(chlortrifluorethylene) oil) has no effect on the transition. In malladrite, Na2SiF6, no obvious phase transitions were observed, at least at pressures below 6 GPa, although some remarkable kinks in the Dc/c(P) and DV/V(P) were measured at about 3.5 GPa. The anisotropy of lattice strain in the highpressure phase of (NH4)2SiF6 was measured up to 6 GPa and compared with that in the trigonal Na2SiF6. The pressure-induced changes in the packing of (SiF6) 2anions were analyzed, the changes in the IR-spectra of (SiF6) 2ions induced by increasing pressure and on decompression were measured and compared for trigonal (NH4)2SiF6 and Na2SiF6. Acknowledgments: Financial support has been obtained from DRL, Alexander von Humboldt Foundation and DLR.
By applying an old result of Y. Berkovich, we provide a polynomial-time algorithm for computing the minimal possible index of a proper subgroup of a finite permutation group [Formula: see text]. Moreover, we find that subgroup explicitly and within the same time if [Formula: see text] is given by a Cayley table. As a corollary, we get an algorithm for testing whether or not a finite permutation group acts on a tree non-trivially.
Actional sentences describe certain ways in which the subjects affect the objects while the object's position in space does not change. The plane of content is the actional proposition, which contains the three necessary components, namely the subject, the object, and the predicate; the plane of expression is the model of the elementary simple sentence where the object position is prototypically expressed by a name in accusative.

In the Khanty and Nenets languages, the actional elementary simple sentences tend to express the same types of relations but differ in their potential for paradigmatic variation. In Tundra Nenets, the communicative variants are related to variation in the choice of accusative, nominative, dative, or instrumental cases in order to express the thematic or rhematic objects and instruments/addressees. In the Kazym dialect of the Khanty language, the accusative form is only used in the system of pronominal declination; in the object position, nouns in nominative case are used. Therefore, to express the thematic-rhematic articulation, verb categories of conjugation (opposition of subject and object conjugation types) are used, as well as genus, because the case system is contracted.

In the Nenets language, the communicative paradigm is related to the variation in name categories, whereas in Khanty, it is related to variation in verb categories.
Learning and memory are among higher-order cognitive functions that are based on numerous molecular processes including changes in the expression of genes. To identify genes associated with learning and memory formation, here, we used the RNA-seq (high-throughput mRNA sequencing) technology to compare hippocampal transcriptomes between mice with high and low Morris water maze (MWM) cognitive performance. We identified 88 differentially expressed genes (DEGs) and 24 differentially alternatively spliced transcripts between the high- and low-MWM-performance mice. Although the sets of DEGs and differentially alternatively spliced transcripts did not overlap, both were found to be enriched with genes related to the same type of biological processes: trans-synaptic signaling, cognition, and glutamatergic transmission. These findings were supported by the results of weighted-gene co-expression network analysis (WGCNA) revealing the enrichment of MWM-cognitive-performance-correlating gene modules with very similar Gene Ontology terms. High-MWM-performance mice manifested mostly higher expression of the genes associated with glutamatergic transmission and long-term potentiation implementation, which are processes necessary for memory acquisition and consolidation. In this set, there were genes participating in the regulation of trans-synaptic signaling, primarily AMPA receptor signaling ( Nrn1 , Nptx1 , Homer3 , Prkce , Napa , Camk2b , Syt7 , and Nrgn ) and calcium turnover ( Hpca , Caln1 , Orai2 , Cpne4 , and Cpne9 ). In high-MWM-performance mice, we also demonstrated significant upregulation of the “flip” splice variant of Gria1 and Gria2 transcripts encoding subunits of AMPA receptor. Altogether, our data helped to identify specific genes in the hippocampus that are associated with learning and long-term memory. We hypothesized that the differences in MWM cognitive performance between the mouse groups are linked with increased long-term potentiation, which is mainly mediated by increased glutamatergic transmission, primarily AMPA receptor signaling.
An active discussion continues in Russia regarding the monetary instruments used and the degree of their impact on economic dynamics. The article examines the impact of the monetary policy implemented by the Central Bank of the Russian Federation on the investment complex in the period from 2000 to 2021. For this period, an analysis of the dependence characterizing the investment complex of Russia on the monetary policy is carried out. In the paper, the investment complex is considered with a breakdown into mechanical engineering, residential and non-residential construction, investments in fixed assets. At the same time, mechanical engineering is studied in detail with a breakdown into subsections of Russian National Classifier of Economic Activities and, additionally, for five enlarged industries. Most of the constructed regression equations demonstrate a statistically significant effect of indicators that are influenced by monetary policy instruments on the dynamics of the main indicators of the investment complex. For example, the interest rate affects the overwhelming number of variables under consideration, and the money supply affects each type of investment in fixed assets, in contrast to other independent variables. For the predominant part of the equations, the value of the coefficient of determination is more than 80%, which indicates a good quality of the model and reliably selected explanatory variables. Based on the results of the calculations, it was concluded that monetary policy has an impact on the investment complex of Russia. This determines its importance for the formation of promising dynamics of the Russian economy.
Somatic mosaicism is something that is observed in everyday lives of cytogeneticists. Chromosome instability is one of the leading causes of large-scale genome variation analyzable since the correct human chromosome number was established in 1956. Somatic mosaicism is also a well-known fact to be present in cases with small supernumerary marker chromosomes (sSMC), i.e. karyotypes of 47,+mar/46. In this study, the data available in the literature were collected concerning the frequency mosaicism in different subgroups of patients with sSMC. Of 3124 cases with sSMC 1626 (52%) present with somatic mosaicism. Some groups like patients with Emanuel-, cat-eye- or i(18p)- syndrome only tend rarely to develop mosaicism, while in Pallister-Killian syndrome every patient is mosaic. In general, acrocentric and nonacrocentric derived sSMCs are differently susceptible to mosaicism; non-acrocentric derived ones are hereby the less stable ones. Even though, in the overwhelming majority of the cases, somatic mosaicism does not have any detectable clinical effects, there are rare cases with altered clinical outcomes due to mosaicism. This is extremely important for prenatal genetic counseling. Overall, as mosaicism is something to be considered in at least every second sSMC case, array-CGH studies cannot be offered as a screening test to reliably detect this kind of chromosomal aberration, as low level mosaic cases and cryptic mosaics are missed by that. Keywords: Mosaic, small supernumerary marker chromosomes (sSMC), genotype-phenotype correlation
Massively parallel reporter assays (MPRAs) enable high-throughput functional evaluation of various DNA regulatory elements and their mutant variants. The assays are based on construction of highly diverse plasmid libraries containing two variable fragments, a region of interest (a sequence under study; ROI) and a barcode (BC) used to uniquely tag each ROI, which are separated by a constant spacer sequence. The sequences of BC–ROI combinations present in the libraries may be either known a priori or not. In the latter case, it is necessary to identify these combinations before performing functional experiments. Typically, this is done by PCR amplification of the BC–ROI regions with flanking primers, followed by next-generation sequencing (NGS) of the products. However, chimeric DNA molecules formed on templates with identical spacer fragment during the amplification process may substantially hamper the identification of genuine BC–ROI combinations, and as a result lower the performance of the assays. To identify settings that minimize formation of chimeric products we tested a number of PCR amplification parameters, such as conventional and emulsion types of PCR, one- or two-round amplification strategies, amount of DNA template, number of PCR cycles, and the duration of the extension step. Using specific MPRA libraries as templates, we found that the two-round amplification of the BC–ROI regions with a very low initial template amount, an elongated extension step, and a specific number of PCR cycles result in as low as 0.30 and 0.32% of chimeric products for emulsion and conventional PCR approaches, respectively. We have identified PCR parameters that ensure synthesis of specific (non-chimeric) products from highly diverse MPRA plasmid libraries. In addition, we found that there is a negligible difference in performance of emulsion and conventional PCR approaches performed with the identified settings.
Raman lasing in multimode GRIN fibers is accompanied by sufficient improvement of the output beam quality in comparison with that for pump radiation, which offers opportunities to wavelength-agile fiber lasers of new type. Here we compare power scaling and brightness enhancement capabilities of Raman laser based on multimode GRIN-fiber of 62.5/125 um core/cladding diameters pumped by ∼700 W multimode source with beam quality M 2 ∼10, performed in two different cavity configurations: 1) linear cavity based on two fiber Bragg gratings and 2) half-open cavity with one FBG and random distributed feedback via Rayleigh backscattering along the GRIN fiber.
Background and objectives Chronic widespread musculoskeletal pain (CWP) is a symptom of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable (48%–54%), but its genetic architecture is unknown and candidate gene studies have produced inconsistent results.

We conducted a genome-wide association study to get insight into the genetic background of CWP. Methods Northern Europeans from UK Biobank comprising 6914 cases reporting pain all over the body lasting >3 months and 242 929 controls were studied. Replication of three independent genome-wide significant single nucleotide polymorphisms was attempted in six independent European cohorts (n=43 080; cases=14 177). Genetic correlations with risk factors, tissue specificity and colocalisation were examined.

Results Three genome-wide significant loci were identified ( rs1491985, rs10490825, rs165599 ) residing within the genes Ring Finger Protein 123 ( RNF123 ), ATPase secretory pathway Ca 2+ transporting 1 ( ATP2C1 ) and catechol-O-methyltransferase ( COMT ). The RNF123 locus was replicated (meta-analysis p=0.0002), the ATP2C1 locus showed suggestive association (p=0.0227) and the COMT locus was not replicated. Partial genetic correlation between CWP and depressive symptoms, body mass index, age of first birth and years of schooling were identified. Tissue specificity and colocalisation analysis highlight the relevance of skeletal muscle in CWP. Conclusions We report a novel association of RNF123 locus and a suggestive association of ATP2C1 locus with CWP. Both loci are consistent with a role of calcium regulation in CWP. The association with COMT , one of the most studied genes in chronic pain field, was not confirmed in the replication analysis.
Wave propagation is considered within the scope of a linear shallow-water theory.

An ill-posed inverse problem is regularized by means of least square inversion using a truncated SVD (singular value decomposition) approach. The method presented allows one to control instability of the numerical solution and to obtain an acceptable result in spite of ill-posedness of the problem.

It is shown that the accuracy of tsunami source reconstruction strongly depends on the signal-to-noise ratio, the azimuthal coverage of recording stations with respect to the source area and bathymetric features along the wave path. The numerical experiments were carried out with synthetic data and various computational domains including a real bathymetry.
The three-body Förster resonances 3 × n P 3/2 (| M |) → n S 1/2 + ( n + 1)S 1/2 + n P 3/2 (| M *|), controlled by a constant electric field, were realised earlier by the authors in an ensemble of several cold Rydberg Rb atoms. One of the drawbacks of such resonances for potential application in three-qubit quantum gates is the proximity of the two-body Förster resonance 2 × n P 3/2 → n S 1/2 + ( n + 1)S 1/2 , as well as the possibility of their implementation only for states with values of the principal quantum numbers n ⩽38. A three-body resonance of a new type, 3 × n P 3/2 → n S 1/2 + ( n + 1)S 1/2 + n P 1/2 , which can be realised for arbitrary n , is proposed and analysed. Its specific feature is also that the third atom transits into a state with a different total angular momentum J = 1/2, which has no Stark structure, so that the two-body resonance is completely absent. Numerical calculations showed that for not too strong interaction, it is possible to observe coherent three-body oscillations of the populations of collective states, which is of interest for developing new schemes of three-qubit quantum gates controlled by an electric field.
Aim. To assess the dynamic changes and clinical significance of biomarkers of inflammatory processes in patients with acute myocardial infarction (MI) with/ or without type 2 diabetes mellitus (T2DM) and primary percutaneous coronary intervention (pPCI) at various stages of treatment. Methods. 96 patients with acute MI after pPCI were examined. The level of inflammation markers was measured 4 times: before pPCI (first day from admission to the hospital), on the third day, 7–10 days (before discharge from the hospital) and 40–45 days after pPCI. Results. All groups of patients with MI showed an increase in the plasma activity of biomarkers of inflammatory processes. After pPCI for 40–45 days, there is a significant difference in the concentration of biomarkers, depending on the comorbid T2DM presence. Strong associations were found between cardiovascular biomarkers and post-MI cardiac remodeling and coronary atherosclerosis progression. Conclusion. The assessment of the levels of biomarkers of inflammatory processes may have additional clinical value in estimating the course of MI, including patients with T2DM at the postinfarction stages.
Dechlorination processes attract great interest since they are involved in environmental protection and waste disposal technologies. In this paper, the process of gas-phase dechlorination of 1,2-dichloroethane, chloroform, and chlorobenzene over Ni/Al2O3 catalyst (90 wt% Ni) prepared by a coprecipitation technique was investigated. The reduction behavior of the oxide precursor NiO/Al2O3 was studied by thermogravimetric analysis in a hydrogen medium. A thermodynamic assessment of the conditions under which metallic nickel undergoes deactivation due to the formation of nickel chloride was performed. The dechlorination of chlorinated substrates was studied using a gravimetric flow-through system equipped with McBain balances in a wide range of temperatures (350–650 °C) and hydrogen concentrations (0–98 vol%). The impact of these parameters on selectivity towards the products of hydrodechlorination (C2H4, C2H6, and C6H6) and catalytic pyrolysis (carbon nanomaterial and CH4) was explored. The relationship between the mechanisms of the catalytic hydrodechlorination and the carbide cycle was discussed, and the specific reaction conditions for the implementation of both scenarios were revealed. According to the electron microscopy data, the carbonaceous products deposited on nickel particles during catalytic pyrolysis are represented by nanofibers with a disordered structure formed due to the peculiarity of the process including the side carbon methanation reaction.
One of the main problems in comparative studying animal behavior is searching for an adequate mathematical method for evaluating the similarities and differences between behavioral patterns.

We developed the new compression-based method for the homogeneity testing and classification to investigate hunting behavior of small mammals. A distinction of this approach is that it belongs to the framework of mathematical statistics and allows one to compare the structural characteristics of any texts in pairwise comparisons. To validate a new method, we compared the hunting behaviors of different species of small mammals as ethological 'texts.' To do this, we coded behavioral elements with different letters. We then tested the hypothesis whether the behavioral sequences of different species as 'texts' are generated either by a single source or by different ones.

Based on association coefficients obtained from pairwise comparisons, we built a new classification of types of hunting behaviors, which brought a unique insight into how particular elements of hunting behavior in rodents changed and evolved. We suggest the compression-based method for homogeneity testing as a relevant tool for behavioral and evolutionary analysis.
Оптимизация переупорядочивания модельных частицпри реализации метода частиц в ячейках на GPU

реализации метода частиц в ячейках на GPU

А. А. Романенко 1 , А. В