Hengzongshu/ArticleAgent huggingface dataset:
The cross section of the process e+e−→π+π−π0 has been measured in the c.m. energy range 984–1060 MeV with the CMD-2 detector at the VEPP-2M collider.

Analysis of the Dalitz plot was performed.

The obtained value of Br(ϕ→e+e−)Br(ϕ→π+π−π0)=(4.51±0.16±0.11)×10−5 is in good agreement with the previous measurements and has the best accuracy. The contributions of the dominant ϕ→ρπ mechanism as well as of a small direct ϕ→3π amplitude were determined.
We compute perturbative corrections to matching coefficients of QCD to heavy quark effective theory (HQET) for the matrix element of the $\mathrm{\ensuremath{\Delta}}B=2$ operator that determines the mass difference in ${B}^{0}\text{\ensuremath{-}}{\overline{B}}^{0}$ system of states. This involves the technical point of choosing the operator basis in HQET, separating physical operators from evanescent ones. We obtain an analytical result for some of the two-loop corrections at order ${\ensuremath{\alpha}}_{s}^{2}$.
There is an attempt to explain some evolutionary processes in plants such as saltatory changes on the base of multidimensionality of plant inherited information coding.According to the suggested hypothesis, inherited information is coded by not only a nucleotide sequence but also by chromosome differential endoreduplication.It is supposed that chromosomes compete among each other for the contact with the nuclear membrane, but a change in the endoreduplication degree of various chromosome sites can result in a change of competition ability for the contact with a nuclear membrane.A simultaneous increase of chromosome endoreduplication degree of many sites can lead to an increase of nuclear membrane surface and to a change in chromosome competitive interrelations and, respectively, to a change of activity of many genes.Phenotypicaly it may manifest itself as a saltatory change of many traits.
The Worldwide LHC Computing Grid infrastructure links about 200 participating computing centres affiliated with several partner projects. It is built by integrating heterogeneous computer and storage resources in diverse data centres all over the world and provides CPU and storage capacity to the LHC experiments to perform data processing and physics analysis. In order to be used by the experiments, these distributed resources should be well described, which implies easy service discovery and detailed description of service configuration. Currently this information is scattered over multiple generic information sources like GOCDB, OIM, BDII and experiment-specific information systems. Such a model does not allow to validate topology and configuration information easily. Moreover, information in various sources is not always consistent. Finally, the evolution of computing technologies introduces new challenges. Experiments are more and more relying on opportunistic resources, which by their nature are more dynamic and should also be well described in the WLCG information system. This contribution describes the new WLCG configuration service CRIC (Computing Resource Information Catalogue) which collects information from various information providers, performs validation and provides a consistent set of UIs and APIs to the LHC VOs for service discovery and usage configuration. The main requirements for CRIC are simplicity, agility and robustness. CRIC should be able to be quickly adapted to new types of computing resources, new information sources, and allow for new data structures to be implemented easily following the evolution of the computing models and operations of the experiments.
Objective: to study the association of hostility with high and low-active variants of the MAOA gene in an open population of men 45-64 years old.

Using the methods proposed by the WHO International Program “MONICA-psychosocial” and “HAPIEE”, a representative sample of men aged 45–64 years old (n = 781 men, average age was 56.48 ± 0.2 years) in 2003-2005. All respondents independently completed a questionnaire on hostility. From the surveyed sample, using the random number method, 156 men were selected who were genotyped for MAOA-uVNTR polymorphism. The results of building a logistic regression model showed that the presence of low-active alleles (2; 3) of the MAOA gene increases the likelihood of hostility OR = 2,103 (95% CI 1,137-3,889, p = 0.018).

It was approved that the level of hostility in the population of men was 60.3%. It was revealed that among persons with low-active alleles of the MAOA-L gene (allele 2 and 3) a high level of hostility was more common — 50.9%. The results obtained allow us to conclude that the low-active allele of the MAOA-L gene is associated with hostility.
We report the relation between the optical properties and electronic structure of lithium thiogallate (LiGaS2) by performing XPS and XES measurements and theoretical calculations. According to the XPS measurements, the LiGaS2 crystals grown by the Bridgman-Stockbarger method possess promising optical qualities, low hygroscopicity and high stability upon middle-energy Ar+-ion irradiation. The difference in the LiGaS2 band gaps obtained by theoretical calculations and experimental measurements was, for the first time, reduced down to 0.27 eV by applying the Tran-Blaha modified Becke-Johnson (TB-mBJ) potential where the Coulomb repulsion was considered by introducing Hubbard parameter, U. The TB-mBJ+U method also reproduces the XPS spectrum well. The TB-mBJ+U band-structure calculations of LiGaS2 are found to be in good agreement with the XPS and XES experimental data. The accurate electronic structure of LiGaS2 allows further investigation of the optical properties. The relation between the photoluminescence of LiGaS2 and its electronic structure was revealed. Moreover, the theoretical results show the possibility of emissions at higher energy levels in LiGaS2, that has not been measured in experiments yet. Good phase-matching of LiGaS2 was expected to occur at energy levels of 5, 6, 6.2, 7, 7.2, and 8 eV.
The cross section of the process $e^{+}e^{-}\rightarrow\eta\pi^{+}\pi^{-}$ is measured using the data collected with the CMD-$3$ detector at the VEPP-$2000$ collider in the center-of-mass energy range from $1.1$ to $2.0$ GeV. The decay mode $\eta\rightarrow\gamma\gamma$ is used for $\eta$ meson reconstruction in the data sample corresponding to an integrated luminosity of $78.3$ pb$^{-1}$. The energy dependence of the $e^{+}e^{-}\rightarrow\eta\pi^{+}\pi^{-}$ cross section is fitted within the framework of vector meson dominance in order to extract the $\Gamma(\rho(1450)\rightarrow{^{+}e^{-}})\mathcal{B}(\rho(1450)\rightarrow\eta\pi^{+}\pi^{-})$ and the $\Gamma(\rho(1700)\rightarrow{e^{+}e^{-}})\mathcal{B}(\rho(1700)\rightarrow\eta\pi^{+}\pi^{-})$ products. Based on conservation of vector current, the analysed data are used to test the relationship between the $e^{+}e^{-}\rightarrow\eta\pi^{+}\pi^{-}$ cross section and the spectral function in $\tau^-\rightarrow\eta\pi^-\pi^0\nu_\tau$ decay. The $e^{+}e^{-}\rightarrow\eta\pi^{+}\pi^{-}$ cross section measured with the CMD-$3$ detector is in good agreement with the previous measurements.
A functional analysis of 167 genes overexpressed in Krebs-2 tumor initiating cells was performed. In the first part of the study, the genes were analyzed for their belonging to one or more of the three groups, which represent the three major phenotypic manifestation of malignancy of cancer cells, namely (1) proliferative self-sufficiency, (2) invasive growth and metastasis, and (3) multiple drug resistance. 96 genes out of 167 were identified as possible contributors to at least one of these fundamental properties. It was also found that substantial part of these genes are also known as genes responsible for formation and/or maintenance of the stemness of normal pluri-/multipotent stem cells. These results suggest that the malignancy is simply the ability to maintain the stem cell specific genes expression profile, and, as a consequence, the stemness itself regardless of the controlling effect of stem niches. In the second part of the study, three stress factors combined into the single concept of "generalized cellular stress," which are assumed to activate the expression of these genes, were defined. In addition, possible mechanisms for such activation were identified. The data obtained suggest the existence of a mechanism for the de novo formation of a pluripotent/stem phenotype in the subpopulation of "committed" tumor cells.
Based on the integral laws of conservation of mass and energy, a mathematical numerical-analytical model of the deformation of a continuous liquid-metal drop after its collision with a flat porous surface is constructed. The model takes into account the capillary and adhesive properties of the melt, the processes of cooling a liquid drop until it solidifies. Numerical calculations are performed for the model case of collision of a continuous liquid drop of zirconia with a porous steel substrate.
We present ANANASTRA, https://ananastra.autosome.org, a web server for the identification and annotation of regulatory single-nucleotide polymorphisms (SNPs) with allele-specific binding events. ANANASTRA accepts a list of dbSNP IDs or a VCF file and reports allele-specific binding (ASB) sites of particular transcription factors or in specific cell types, highlighting those with ASBs significantly enriched at SNPs in the query list. ANANASTRA is built on top of a systematic analysis of allelic imbalance in ChIP-Seq experiments and performs the ASB enrichment test against background sets of SNPs found in the same source experiments as ASB sites but not displaying significant allelic imbalance. We illustrate ANANASTRA usage with selected case studies and expect that ANANASTRA will help to conduct the follow-up of GWAS in terms of establishing functional hypotheses and designing experimental verification.
An attempt is made to explain time non-dilation allegedly observed in quasar light curves. The explanation is based on the assumption that quasar black holes are, in some sense, foreign for our Friedmann-Robertson-Walker universe and do not participate in the Hubble flow. Although at first sight such a weird explanation requires unreasonably fine-tuned Big Bang initial conditions, we find a natural justification for it using the Milne cosmological model as an inspiration.
In this paper, the influence of surface modification on the characteristics and properties of AlN thin films on Si and glass-ceramics substrates is investigated. The surface modification was made at various parameters of argon cluster ions. By using XRD and Raman spectroscopy, it was shown that the obtained AlN films have a hexagonal structure with a characteristic direction of texturing along the c axis and slight deviations from it. A comparison of the AlN surface morphology obtained by atomic force microscopy before and after cluster processing was demonstrated. This demonstrated that the cluster ions with low energy per atom (E/N = 10 eV/atom) have a high efficiency of surface smoothing. A decrease in the intensity of the Raman peaks and an increase in their full-width after bombardment with cluster ions were found, which may be caused by a change in the physicochemical state of the surface. The optical properties, the quality of the boundaries, and the distribution map of the thickness of the functional layer of AlN were investigated by the methods of spectral and spatial resolution ellipsometry. By using the cross-sectional SEM, the direction of crystallite texturing was demonstrated. The influence of argon cluster ion bombardment on the stoichiometry of samples was analyzed by EDX spectroscopy. The results obtained demonstrate the efficiency of the cluster ion smoothing of polycrystalline thin films for microelectronics, particularly when creating surface acoustic wave resonators.
Experimental dependency of the photosystem's response on the wavelength of exciting radiation, also known as action spectrum, may be substantially affected by the spectrum shape of this radiation. This is especially important in the case, when different radiation sources are used for the investigation of action spectrum. For instance, too wide emission peaks of radiation sources can blur the scopes of actual action spectrum and distort information about the properties of photosystem at certain wavelength regions.

Here, we propose a method for the correction of experimental action spectrum by the recalculation of experimental data of photoresponse according to actual spectra of exciting radiation. In the case of overlapping radiation spectra from different radiation sources, this method results in much better correlation of experimental action spectrum to actual action spectrum or absorption spectrum of photosystem.

The data on photoactivity of several photocatalysts are presented to illustrate and validate the proposed method. Activity of photosystem depends on the actual spectrum of the radiation source Single-peak optical radiation sources with the same basic wavelength may cause a different photoactivity Effect of actual spectrum of the light source on the photoactivity is to be considered
The APPL1 gene encodes a protein mediating the cross-talk between adiponectin and insulin signaling. Recently, it was found that APPL1 mutations can cause maturity onset diabetes of the young, type 14. Here, an analysis of APPL1 was performed in patients with a maturity-onset diabetes of the young (MODY) phenotype, and prevalence of these mutations was estimated in a Russian population, among type 2 diabetes mellitus (T2DM) and MODY patients. Whole-exome sequencing or targeted sequencing was performed on 151 probands with a MODY phenotype, with subsequent association analysis of one of identified variants, rs11544593, in a white population of Western Siberia (276 control subjects and 169 T2DM patients). Thirteen variants were found in APPL1, three of which (rs79282761, rs138485817, and rs11544593) are located in exons. There were no statistically significant differences in the frequencies of rs11544593 alleles and genotypes between T2DM patients and the general population. In the MODY group, AG rs11544593 genotype carriers were significantly more frequent (AG vs. AA + GG: odds ratio 1.83, confidence interval 1.15–2.90, p = 0.011) compared with the control group. An association of rs11544593 with blood glucose concentration was revealed in the MODY group. The genotyping data suggest that rs11544593 may contribute to carbohydrate metabolism disturbances.
Unlike many other viruses, HIV-1 is highly variable. The structure of the viral envelope changes as the infection progresses and is one of the biggest obstacles in developing an HIV-1 vaccine. HIV-1 infection can cause the production of various natural autoantibodies, including catalytic antibodies hydrolyzing DNA, myelin basic protein, histones, HIV-integrase, HIV-reverse transcriptase, β-casein, serum albumin, and some other natural substrates. Currently, there are various directions for the development of HIV-1 vaccines: stimulation of the immune response on the mucous membranes; induction of cytotoxic T cells, which lyse infected cells and hold back HIV-infection; immunization with recombinant Env proteins or vectors encoding Env; mRNA-based vaccines and some others. However, despite many attempts to develop an HIV-1 vaccine, none have been successful. Here we review the entire spectrum of antibodies found in HIV-infected patients, including neutralizing antibodies specific to various viral epitopes, as well as antibodies formed against various autoantigens, catalytic antibodies against autoantigens, and some viral proteins. We consider various promising targets for developing a vaccine that will not produce unwanted antibodies in vaccinated patients. In addition, we review common problems in the development of a vaccine against HIV-1.
An analysis is made of the effect of a strong field on the shape of the amplification spectral line for mono-velocity V-type three-level atoms. There are three strong-field contributions, differing in their dependence on the set of relaxation parameters of the medium and on the differences among the populations corresponding to the Raman transitions. An analysis is made of the conditions under which each of the contributions is predominant. The change in the line shape by an intensified external field is found for each case. Neon atoms are discussed as an example. The results are compared with those corresponding to a Maxwellian velocity distribution.
СТРУКТУРНЫЕ ПРЕОБРАЗОВАНИЯ В АКСИЛЛЯРНЫХ И БРЫЖЕЕЧНЫХ ЛИМФАТИЧЕСКИХ УЗЛАХ ПРИ ХИМИОТЕРАПИИ И ОПЕРАТИВНОМ ЛЕЧЕНИИ ЭКСПЕРИМЕНТАЛЬНОГО РАКА МОЛОЧНОЙ ЖЕЛЕЗЫОлег Васильевич КАЗАКОВ,
In polytene chromosomes of Drosophila melanogaster, regions of pericentric heterochromatin coalesce to form a compact chromocenter and are highly underreplicated. Focusing on study of X chromosome heterochromatin, we demonstrate that loss of either SU(VAR)3-9 histone methyltransferase activity or HP1 protein differentially affects the compaction of different pericentric regions. Using a set of inversions breaking X chromosome heterochromatin in the background of the Su(var)3-9 mutations, we show that distal heterochromatin (blocks h26-h29) is the only one within the chromocenter to form a big "puff"-like structure. The "puffed" heterochromatin has not only unique morphology but also very special protein composition as well: (i) it does not bind proteins specific for active chromatin and should therefore be referred to as a pseudopuff and (ii) it strongly associates with heterochromatin-specific proteins SU(VAR)3-7 and SUUR, despite the fact that HP1 and HP2 are depleted particularly from this polytene structure. The pseudopuff completes replication earlier than when it is compacted as heterochromatin, and underreplication of some DNA sequences within the pseudopuff is strongly suppressed. So, we show that pericentric heterochromatin is heterogeneous in its requirement for SU(VAR)3-9 with respect to the establishment of the condensed state, time of replication, and DNA polytenization.
The problem of the existence of an additional (independent on the energy) first integral, of a geodesic (or magnetic geodesic) flow, which is polynomial in momenta is studied.

The relation of this problem to the existence of nontrivial solutions of stationary dispersionless limits of two-dimensional soliton equations is demonstrated.

The nonexistence of an additional quadratic first integral is established for certain classes of magnetic geodesic flows.
Influence of treating with limited doses of steams of ethanol on a transpositions MGE412 was investigated in the males from isogenic lines of Drosophila melanogaster. It was proved the phenomenon of the induction. The rates of induced transpositions was estimated. Ones was 3,79-6,89xl0~2 in comparison with control, A.k=l,84xl0x 3. It was established that alcohol made be finished either death of individuals or increase genetic variability in the posterity. It was proved that ethanol is powerful inductor of transpositions MGEs of Drosophila like other different external (temperature shock, y-irradiation) and genetic factors, the main of them are isogenization and selection
Obesity is heritable. It predisposes to many diseases. The objectives of this study were to create a compendium of genes relevant to feeding behavior (FB) and/or body weight (BW) regulation; to construct and to analyze networks formed by associations between genes/proteins; and to identify the most significant genes, biological processes/pathways, and tissues/organs involved in BW regulation. The compendium of genes controlling FB or BW includes 578 human genes. Candidate genes were identified from various sources, including previously published original research and review articles, GWAS meta-analyses, and OMIM (Online Mendelian Inheritance in Man).

All genes were ranked according to knowledge about their biological role in body weight regulation and classified according to expression patterns or functional characteristics. Substantial and overrepresented numbers of genes from the compendium encoded cell surface receptors, signaling molecules (hormones, neuropeptides, cytokines), transcription factors, signal transduction proteins, cilium and BBSome components, and lipid binding proteins or were present in the brain-specific list of tissue-enriched genes identified with TSEA tool. We identified 27 pathways from KEGG, REACTOME and BIOCARTA whose genes were overrepresented in the compendium. Networks formed by physical interactions or homological relationships between proteins or interactions between proteins involved in biochemical/signaling pathways were reconstructed and analyzed. Subnetworks and clusters identified by the MCODE tool included genes/proteins associated with cilium morphogenesis, signal transduction proteins (particularly, G protein–coupled receptors, kinases or proteins involved in response to insulin stimulus) and transcription regulation (particularly nuclear receptors). We ranked GWAS genes according to the number of neighbors in three networks and revealed 22 GWAS genes involved in the brain-specific PPI network.

On the base of the most reliable PPIs functioning in the brain tissue, new regulatory schemes interpreting relevance to BW regulation are proposed for three GWAS genes (ETV5, LRP1B, and NDUFS3). A compendium comprising 578 human genes controlling FB or BW was designed, and the most significant functional groups of genes, biological processes/pathways, and tissues/organs involved in BW regulation were revealed. We ranked genes from the GWAS meta-analysis set according to the number and quality of associations in the networks and then according to their involvement in the brain-specific PPI network and proposed new regulatory schemes involving three GWAS genes (ETV5, LRP1B, and NDUFS3) in BW regulation. The compendium is expected to be useful for pathology risk estimation and for design of new pharmacological approaches in the treatment of human obesity.
We consider one-loop self-energy and vacuum polarization radiative corrections to the shift of atomic energy level due to finite nuclear size. Analytic expressions for vacuum polarization corrections are derived. For the self-energy of ${p}_{1/2}$ and ${p}_{3/2}$ states in addition to already known terms we derive next-to-leading nonlogarithmic $Z\ensuremath{\alpha}$ terms. Together with contributions obtained earlier the terms derived in the present work give explicit analytic expressions for ${s}_{1/2}$ and ${p}_{1/2}$ corrections which agree with results of previous numerical calculations up to $Z=100$ $(Z$ is the nuclear charge number). We also show that the finite-nuclear-size radiative correction for a ${p}_{3/2}$ state is not small compared to the similar correction for a ${p}_{1/2}$ state at least for small Z.
The reaction of the Pn ligand complex [Cp*Fe(η5-P5)] (1: Cp* = η5-C5Me5) with CuCl in the presence of 4,4′-bipyridine or 1,2-di(4-pyridyl)ethylene leads to the formation of three unprecedented neutral 2D organometallic–organic hybrid networks.
We consider a problem of minimum length scheduling for the conflict-free aggregation convergecast in wireless networks in a case when each element of a network uses its own frequency channel. This problem is equivalent to the well-known NP-hard problem of telephone broadcasting since only the conflicts between the children of the same parent are taken into account.

We propose a new integer programming formulation and compare it with the known one by running the CPLEX software package. We also propose a novel heuristic algorithm, which is based on a genetic algorithm and a local search metaheuristic.

Based on the results of a numerical experiment, we concluded that our formulation is more preferable in practice to solve the considered problem by CPLEX than the known one. The simulation results demonstrate the high quality of the proposed algorithm compared to the best known approaches.