Hengzongshu/ArticleAgent huggingface dataset:
The 3-D printers offered to the construction market can perform retained form layer-by-layer for subsequent filling with reinforced structural concrete and insulation. The use of a single-stage polystyrene concrete with polystyrene granules bloated directly in the printer head allows to form layer-by-layer the insulated wall for its entire width and reduce the erection operation to one technological conversion.
To study the monuments of diplomatic correspondence from the sixteenth century as a source of political thought in the successor states of the Golden Horde.

The messages of Crimean khans, sultans, representatives of ruling groups, Nogai beks and mirzas preserved in translated copies in the ambassadorial books of the Muscovite state. For the first time ever, the diplomatic documents of the Crimean khanate and the Nogai Horde are involved in the reconstruction of their period’s corpus of political ideas. Considering the question of the authorship of messages, we proceed with the concept of S.M. Kashtanov about “technical authorship”, in which the authorship is understood as the collective work of rulers, courtiers, bureaucrats, and technical workers on the creation of a letter.

The application of the concept of “corporate authorship” has made it possible to show that diplomatic messages were always a product of some convention possible within the elite that were involved in the development of foreign policy. Translators played an important role in shaping the political language. The messages of the khans, sultans, beks, and mirzas of the successor states of the Golden Horde contain some ideas that can help us to outline the political ideology. Central to it is the thesis of the exclusive right to power of the Chinggisids who could get power only with the general consent of the “political people”. “Evil” and “good” were the most important concepts of thought in the successor states. “Evil” was understood as any change in the established order, and “good” as its preservation. Thus, conservatism and the desire to fix the rituals of power and management practices that had developed earlier in the era of the Golden Horde were the most important concepts for political life in the successor states. This attitude led to the preservation of earlier concepts and terminological language, something which was reflected in the practice of diplomacy when the elusive reality of former power influenced ambassadorial ceremony and the form of messages.
The sequence of oocyte maturation in the fetal ovary of the house shrew, Suncus murinus is analyzed by means of light and electron microscopy of surface-spread silver-stained preparations.

The progression of cells is relatively synchronous. Meiotic prophase starts at day 20 of gestation. The peak of pachytene cells occurs on day 23. On day 24 diplotene cells are abundant. They are characterized by premature desynapsis and separation of axial elements of some bivalents. The meotic prophase is completed on day 26, when the majority of oocytes reach the dictyotene stage.
Particle-laden flow in 3D supersonic micronozzle with rectangular cross-section and side walls convergent/divergent in both lateral and transversal direction is studied numerically using a one-way coupled Eulerian/Lagrangian approach.

The carrier gas flow is simulated numerically on the basis of the Navier-Stokes equations and then is used to calculate the particles trajectories.

It is shown that a collimated beam of particles can be produced using the effect of aerodynamic focusing and the beam collimation is observed in two different ranges of particle sizes. Obtained results are consistent with previously obtained data for plane and axisymmetrical nozzles.
Despite the high degree of archaeological and anthropological research of the Tagar culture and its carriers, many directions of study of this Sothern Siberian Iron Age population remain relevant. This work is devoted to the consideration of the data on the genetic composition of the Tagar culture population, obtained to date by paleogenetic methods. The study of representative mtDNA sample series from chronologically different groups of the Tagar population (N = 79), carried out by the authors of this work, allow us to obtain the first objective view on the composition of its mitochondrial gene pool. The obtained results illustrate well the significance of analysis of representative sample series when performing paleogenetic reconstructions. The general Tagar population is characterized by the presence in the gene pool of both Western Eurasian (H, HV6, HV*, I, K, T, U2e, U4, U5a, and U*) and Eastern Eurasian (A*, A8, C*, C5, D, G2a, F1b) mtDNA haplogroups. Unlike other populations of southern Siberia of the Scythian time, Western Eurasian variants dominate in the Tagar gene pool. Among the previous populations, the Tagar population demonstrates affinity with the populations of the Minusinsk Basin of the Middle Bronze Age. When compared with the groups of early nomads of Eurasia, the Tagar population shows a similarity in terms of the mtDNA variability with the carriers of other cultures of the Scythian circle, occupying an intermediate position between the geographically distant Scythians of the Northern Black Sea region and the population of the south Siberian cultures, Pazyryk and Aldy-Bel. During the transition from the Podgorny to the Saragashen stages, the Tagar population converges with other groups of early nomads of southern Siberia. In the Tagar gene pool of the Y chromosome, the dominance of variants of the R1a1a haplogroup was revealed. This genetic cluster was first introduced into the Minusinsk Basin by the carriers of the Andronovo (Fedorovo) culture. However, additional in-depth analysis of the Tagar Y chromosome lineages is required to clarify their origin. The paper presents the most promising directions for further research of the Tagar populations using paleogenetic methods.
Влияние институциональной среды на корпоративные практики управления в российских компаниях О. В. Валиева Институт экономики и организации промышленного производства СО РАН Новосибирский национальный исследовательский государственный университет Новосибирск, Россия Аннотация Анализ влияния институциональной среды на формирование современных корпоративных практик имеет большое значение в контексте повышения эффективности управления в российских компаниях.Основным направлением исследования является определение степени влияния институциональной среды на формирование корпоративных управленческих практик и устойчивых организационных рутин.В статье приводятся результаты опросов руководителей среднего и высшего звена компаний Сибирского федерального округа (СФО).Результаты исследования показали, что на протяжении целого ряда лет наиболее значимыми для компаний оставались практики управления внешними и внутренними информационными потоками, нестандартные управленческие подходы, распределение формальной и неформальной власти в компаниях.Анализ опросов в динамике за период 2012-2016 гг.выявил усиление влияния налоговой и коррупционной составляющей на деятельность компаний СФО
This paper outlines the main approaches to the automation of the process of statistical analysis of the lower structural levels (meter, rhythm, phonetics, vocabulary, grammar) of poetic texts, as well as the algorithms for complex analysis of poetic texts in the Kazakh language are presented in order to automate the process of creation of metric dictionaries and concordances. The results of this analysis will significantly expand the possibilities of the philologists who study both these levels of poetry and their semantic and pragmatic characteristics, and also will rid the philologists of routine work, will expand the range of analyzed works, by reducing the dependence of the quality of comparative analysis on the personal erudition of the researcher.
ИСПОЛЬЗОВАНИЕ ГЕНОВ Vrn ДЛЯ СОЗДАНИЯ ФОРМ ТРИТИКАЛЕ С РАЗНОЙ ПРОДОЛЖИТЕЛЬНОСТЬЮ ВЕГЕТАЦИОННОГО ПЕРИОДА  (обзор) М.В.ЕМЦЕВА Тритикале (½ Triticosecale Wittmack) -новая сельскохозяйственная культура, объединяющая в себе ценные свойства пшеницы и ржи.К преимуществам тритикале относятся способность произрастать на бедных, кислых, подтопляемых почвах, более высокое
An electron outcoupling scheme was proposed for the high power FELs with optical cavities to avoid the power limitation because of overheating of the reflecting mirrors.

This can be realized if the major part of radiation power is emitted at an angle to the optical axis. For this, the electron beam should be bunched and then slightly rotated in an undulator of the FEL. At the NovoFEL facility, the electron outcoupling system is installed on the third FEL, based on the multi-turn energy recovery linac. It consists of three undulators, dipole correctors, and two quadrupole lenses assembled between them. There are two different configurations of the system, with electrons deflected in either the second or the third undulator.

The electron beam dynamics calculations, current experimental results, and planned experiments are discussed.
Two polymorphs of tolazamide, N-[(azepan-1-ylamino)carbonyl]-4-methylbenzenesulfonamide, a sulfonylurea anti-diabetic drug, have different densities and molecular packings. Polymorph II converts into polymorph I in the solid state on heating or via recrystallization if solvent-assisted.

The effect of pressure on the two forms and the possibility of a transformation to a denser form on compression have been studied. No phase transitions have been observed in either of the forms in a pentane–isopentane mixture (when no recrystallization is possible). Polymorph II recrystallized partly into a denser polymorph I in methanol at 0.1 GPa, but the transformation stopped at an early stage. Solid state DFT calculations of the two forms as well as conformational landscape investigation in the gas phase were used to rationalize this result.

The anisotropic pressure-induced strain of the two polymorphs has been compared in relation to changes in the hydrogen bond geometry and the behavior of stacking interactions.
Reprogramming of somatic cells to a pluripotent state is a complex, multistage process that is regulated by many factors. Among these factors, non-coding RNAs and microRNAs (miRNAs) have been intensively studied in recent years. MiRNAs play an important role in many processes, particularly in cell reprogramming. In this study, we investigated the reprogramming of rat fibroblasts with a deleted locus encoding a cluster comprising 14 miRNAs (from miR-743a to miR-465). The deletion of this locus was demonstrated to decrease significantly the efficiency of the cell reprogramming. In addition, the cells produced by the reprogramming differed from rat embryonic and induced pluripotent stem cells, which was an indication that reprogramming in these cells had not been completed. We suggest that this miRNA cluster or some of its members are involved in regulating the reprogramming of rat cells to a pluripotent state.
The functions of the hypothalamic adrenal cortical and sympathetic adrenal medullary systems were studied in rats with inherited stress-induced arterial hypertension (ISIAH strain). A characteristic feature of the ISIAH strain is an increase in arterial blood pressure measured both under basal conditions and after restraint stress in particular.

In the control ISIAH rats, the basal plasma ACTH concentration was slightly lower than that in the normotensive Wistar albino Glaxo (WAG) rats, and no differences were found in plasma corticosterone. However, the 0.5-h restraint stress produced higher activation of the adrenal cortex in the ISIAH rats. Gluco- and mineralocorticoid responses to the blood volume reduction stresses and ACTH and corticosterone responses to social stress were stronger in the ISIAH than in the control WAG rats. An increase in epinephrine content in adrenals in the basal state and enhanced response of the sympathetic adrenal medullary system to handling stress were observed in the ISIAH rats. Restraint stress produced significantly higher expression of genes encoding corticotropin-releasing hormone-mRNA in hypothalamus and proopiomelanocortin-mRNA in pituitary in the ISIAH than in the WAG rats. Restraint stress produced a decrease in glucocorticoid receptor (GR) gene expression (GR-mRNA) in hippocampus in the ISIAH, but not in the WAG rats. A persistent increase in tyrosine hydroxylase-mRNA in adrenals of the ISIAH rats was found.

It is concluded that the ISIAH rat strain is an appropriate model of stress-sensitive hypertension with the predominant involvement of the hypothalamic adrenal cortical and sympathetic adrenal medullary systems in its pathogenesis.
Apurinic/apyrimidinic (AP) endonucleases play critical roles in the repair of abasic sites and strand breaks in DNA. Complete genome sequences of Helicobacter pylori reveal that this bacterial specie has a single AP endonuclease. An H. pylori homolog of Xth (HpXth) is a member of exonuclease III family, which is represented by Escherichia coli Xth. Currently, it remains unknown whether this single AP endonuclease has DNA repair activities similar to those of its counterpart in E. coli and other bacteria.

We report that HpXth possesses efficient AP site cleavage, 3'-repair phosphodiesterase, and 3'-phosphatase activities but not the nucleotide incision repair function. Optimal reaction conditions for HpXth's AP endonuclease activity are low ionic strength, high Mg2+ concentration, pH in the range 7–8, and temperature 30 °C. The kinetic parameters measured under steady-state conditions showed that HpXth removes the AP site, 3'-blocking sugar-phosphate, and 3'-terminal phosphate in DNA strand breaks with good efficiency (kcat/KM = 1240, 44, and 5,4 μM–1·min–1, respectively), similar to that of E. coli Xth. Mutation of active site residue D144 in HpXth predicted to be essential for catalysis resulted in a complete loss of enzyme activities. Several important structural features of HpXth were uncovered by homology modeling and phylogenetic analysis.

As expected, the presence of HpXth protein in AP endonuclease—deficient E. coli xth nfo strain significantly reduced the sensitivity to an alkylating agent and H2O2. Our data show the DNA substrate specificity of H. pylori AP endonuclease and suggest that HpXth counteracts the genotoxic effects of DNA damage generated by endogenous and host-imposed factors.
This Letter presents a search at the LHC for s-channel single top-quark production in proton–proton collisions at a centre-of-mass energy of 8 TeV. The analyzed data set was recorded by the ATLAS detector and corresponds to an integrated luminosity of 20.3 fb−1.

Selected events contain one charged lepton, large missing transverse momentum and exactly two b-tagged jets. A multivariate event classifier based on boosted decision trees is developed to discriminate s-channel single top-quark events from the main background contributions. The signal extraction is based on a binned maximum-likelihood fit of the output classifier distribution.

The analysis leads to an upper limit on the s-channel single top-quark production cross-section of 14.6 pb at the 95% confidence level. The fit gives a cross-section of σs=5.0±4.3pb, consistent with the Standard Model expectation.
The current article deals with the dichotomy communication -transference with respect to the earlier opened dichotomy synchrony-diachrony.

The new type of transference is discussed.It is based on the role of performatives as messages which cannot be denied by logics.

"Communication" and "transference" play a significant role in preserving non-genetic data.The transference is considered to be a cognitive process, which is aimed at storing information in generations.
Background Although ageing populations are increasingly residing in cities, it is unknown whether depression inequalities are moderated by urbanicity degree. We estimated gender, marital and educational inequalities in depressive symptoms among older European and Canadian adults, and examined whether higher levels of urbanicity, captured by population density, heightened these inequalities. Methods Harmonised cross-sectional data on 97 826 adults aged ≥50 years from eight cohorts were used. Prevalence ratios (PRs) were calculated for probable depression, depressed affect and depressive symptom severity by gender, marital status and education within each cohort, and combined using random-effects meta-analysis. Using a subsample of 73 123 adults from six cohorts with available data on population density, we tested moderating effects measured by the number of residents per square kilometre. Results The pooled PRs for probable depression by female gender, unmarried or non-cohabitating status and low education were 1.48 (95% CI 1.28 to 1.72), 1.44 (95% CI 1.29 to 1.61) and 1.29 (95% CI 1.18 to 1.41), respectively. PRs for depressed affect and high symptom severity were broadly similar. Except for one Dutch cohort with findings in an unexpected direction, there was no evidence that population density modified depressive symptom inequalities. Conclusions Despite cross-cohort variation in gender, marital status and educational inequalities in depressive symptoms, there was weak evidence that these inequalities differed by levels of population density.
The molecular dynamics study of the rearrangement of the dynamic hydrogen bond network of liquid water to the crystal hydrogen bond network of methane hydrate in the process of their formation and growth is conducted. To reveal the nature of nucleation, the time dependences of the degree of “crystallinity” of the nearest environment of all water molecules, the rate of ordering of the hydrogen bond network, and the relation of these parameters to the rate of growth of methane hydrate are studied. The effect of the presence of sea salt ions and hydrate seed on these parameters is analyzed. Systems with a completely mixed gas, i.e., with the minimum induction time, are fabricated, and it is shown that gas hydrates can be nucleated simultaneously in the entire volume of the solution, which in turn indicates the collective formation of hydrates from liquid solution.
Polynuclear bismuth(III) iodide complexes with 1-ethyl-4-dimethylaminopyridinium (1-EtDMAP) 4 [Bi 8 I 28 ] ( 1 ) and (1-EtDMAP)BiI 4 ( 2 ) have been obtained by the reactions of bismuth(III) iodide with an organic iodide salt cations in organic solvents

characterized by X-ray diffraction

The optical properties and thermal stability of the obtained compounds have been studied
Inhibition of DNA repair enzymes by the ruthenium nitrosyl complex

occurs only after light irradiation and is determined by the interactions between the enzyme and active photolysis products

Inhibition of DNA repair enzymes by the ruthenium nitrosyl complex occurs only after light irradiation and is determined by the interactions between the enzyme and active photolysis products
Recent results on e + e − annihilation to hadrons from SND experiment at VEPP-2000 collider are presented.

Corresponding data set is about 200 pb −1 of integrated luminosity collected at the energy region below 2 GeV.

The processes e + e − → π + π − , π 0 γ, ωπ 0 , π + π − π 0 , ηπ + π − π 0 , η , π + π − 4π 0 have been studied. Searches for e + e − annihilation to C -even resonances η and f 1(1285) were done.
The ability of frustrated Lewis pairs (FLPs) to activate H2 is of significant interest for metal-free catalysis. The activation of H2 is also the key element of parahydrogen-induced polarization (PHIP), one of the nuclear spin hyperpolarization techniques. It is demonstrated that o-phenylene-based ansa-aminoboranes (AABs) can produce 1H nuclear spin hyperpolarization through a reversible interaction with parahydrogen at ambient temperatures. Heteronuclei are useful in NMR and MRI as well because they have a broad chemical shift range and long relaxation times and may act as background-free labels. We report spontaneous formation of 15N hyperpolarization of the N-H site for a family of AABs. The process is efficient at the high magnetic field of an NMR magnet (7 T), and it provides up to 350-fold 15N signal enhancements. Different hyperpolarization effects are observed with various AAB structures and in a broad temperature range. Spontaneous hyperpolarization, albeit an order of magnitude weaker than that for 15N, was also observed for 11B nuclei.
Despite significant achievements in the elucidation of the nature of protein-DNA contacts that control the specificity of nucleotide incision repair (NIR) by apurinic/apyrimidinic (AP) endonucleases, the question on how a given nucleotide is accommodated by the active site of the enzyme remains unanswered.

Therefore, the main purpose of our study was to compare kinetics of conformational changes of three homologous APE1-like endonucleases (insect Drosophila melanogaster Rrp1, amphibian Xenopus laevis xAPE1, and fish Danio rerio zAPE1) during their interaction with various damaged DNA substrates, i.e., DNA containing an F-site (an uncleavable by DNA-glycosylases analog of an AP-site), 1, N 6 -ethenoadenosine (εA), 5,6-dihydrouridine (DHU), uridine (U), or the α-anomer of adenosine (αA). Pre-steady-state analysis of fluorescence time courses obtained for the interaction of the APE1-like enzymes with DNA substrates containing various lesions allowed us to outline a model of substrate recognition by this class of enzymes.

It was found that the differences in rates of DNA substrates' binding do not lead to significant differences in the cleavage efficiency of DNA containing a damaged base. The results suggest that the formation of enzyme–substrate complexes is not the key factor that limits enzyme turnover; the mechanisms of damage recognition and cleavage efficacy are related to fine conformational tuning inside the active site.
. Flavin adenine dinucleotide (FAD) is an important cofactor in many light-sensitive enzymes. The role of the adenine moiety of FAD in light-induced electron transfer was obscured, because it involves an adenine radical, which is short-lived with a weak chromophore. However, an intramolecular electron transfer from adenine to flavin was revealed several years ago by Robert Kaptein by using chemically induced dynamic nuclear polarization (CIDNP). The question of whether one or two types of biradicals of FAD in aqueous solution are formed stays unresolved so far. In the present work, we revisited the CIDNP study of FAD using a robust mechanical sample shuttling setup covering a wide magnetic field range with sample illumination by a light-emitting diode. Also, a cost efficient fast field cycling apparatus with high spectral resolution detection up to 16.4 T for nuclear magnetic relaxation dispersion studies was built based on a 700 MHz NMR spectrometer. Site-specific proton relaxation dispersion data for FAD show a strong restriction of the relative motion of its isoalloxazine and adenine rings with coincident correlation times for adenine, flavin, and their ribityl phosphate linker. This finding is consistent with the assumption that the molecular structure of FAD is rigid and compact. The structure with close proximity of the isoalloxazine and purine moieties is favorable for reversible light-induced intramolecular electron transfer from adenine to triplet excited flavin with formation of a transient spin-correlated triplet biradical F⚫−-A⚫+. Spin-selective recombination of the biradical leads to the formation of CIDNP with a common emissive maximum at 4.0 mT detected for adenine and flavin protons. Careful correction of the CIDNP data for relaxation losses during sample shuttling shows that only a single maximum of CIDNP is formed in the magnetic field range from 0.1 mT to 9 T; thus, only one type of FAD biradical is detectable. Modeling of the CIDNP field dependence provides good agreement with the experimental data for a normal distance distribution between the two radical centers around 0.89 nm and an effective electron exchange interaction of −2.0 mT.