Hengzongshu/ArticleAgent huggingface dataset:
Defect structure and morphology of CdS and (Cd,Mn)S nanocrystalline samples synthesized by hydrothermal synthesis at temperatures of 80, 100, 120, and 140° C were investigated.The full-profile analysis by the Rietveld method showed that the experimental X-ray diffraction patterns do not correspond to either the cubic structure of the sphalerite or the hexagonal structure of wurtzite, which are characteristic of well-crystalline CdS.In addition, Xray diffraction patterns are not fitted by scattering on a mixture of these two modifications.

Simulation of X-ray diffraction patterns with use of Debye scattering equation [1] showed that CdS and (Cd,Mn)S nanoparticles contain high consentraition of stacking faults (SFs).Optimization of the structural models using the genetic algorithm showed that the probability of SFs (relative to the wurtzite structure) decreases for CdS from 0.55 to 0.46, and for (Cd,Mn)S from 0.47 to 0.36.

Therefore, the structure of nanoparticles in both series gradually approaches the structure of wurtzite.It was also shown that at all synthesis temperatures the CdS and (Cd,Mn)S particles have an ellipsoidal shape, with the ellipsoids stretched along the direction perpendicular to the SFs.With an increase in the synthesis temperature, the average particle size increases.Ellipsoidal shape of particles was confirmed by TEM data.
This paper presents the results of measuring the duration of the zone of high electrical conductivity during detonation of RDX of different density

It is shown that the density of RDX has a weak effect on the duration of this zone
Boron neutron capture therapy is a unique form of adjuvant cancer therapy for various malignancies including malignant gliomas. The conjugation of boron compounds and human serum albumin (HSA)-a carrier protein with a long plasma half-life-is expected to extend systemic circulation of the boron compounds and increase their accumulation in human glioma cells. We report on the synthesis of fluorophore-labeled homocystamide conjugates of human serum albumin and their use in thiol-'click' chemistry to prepare novel multimodal boronated albumin-based theranostic agents, which could be accumulated in tumor cells. The novelty of this work involves the development of the synthesis methodology of albumin conjugates for the imaging-guided boron neutron capture therapy combination. Herein, we suggest using thenoyltrifluoroacetone as a part of an anticancer theranostic construct: approximately 5.4 molecules of thenoyltrifluoroacetone were bound to each albumin. Along with its beneficial properties as a chemotherapeutic agent, thenoyltrifluoroacetone is a promising magnetic resonance imaging agent. The conjugation of bimodal HSA with undecahydro-closo-dodecaborate only slightly reduced human glioma cell line viability in the absence of irradiation (~30 μM of boronated albumin) but allowed for neutron capture and decreased tumor cell survival under epithermal neutron flux. The simultaneous presence of undecahydro-closo-dodecaborate and labeled amino acid residues (fluorophore dye and fluorine atoms) in the obtained HSA conjugate makes it a promising candidate for the combination imaging-guided boron neutron capture therapy.
Human 8-oxoguanine DNA glycosylase (hOGG1) is a key enzyme responsible for initiating the base excision repair of 7,8-dihydro-8-oxoguanosine (oxoG). In this study a thermodynamic analysis of the interaction of hOGG1 with specific and non-specific DNA-substrates is performed based on stopped-flow kinetic data. The standard Gibbs energies, enthalpies and entropies of specific stages of the repair process were determined via kinetic measurements over a temperature range using the van't Hoff approach. The three steps which are accompanied with changes in the DNA conformations were detected via 2-aminopurine fluorescence in the process of binding and recognition of damaged oxoG base by hOGG1. The thermodynamic analysis has demonstrated that the initial step of the DNA substrates binding is mainly governed by energy due to favorable interactions in the process of formation of the recognition contacts, which results in negative enthalpy change, as well as due to partial desolvation of the surface between the DNA and enzyme, which results in positive entropy change. Discrimination of non-specific G base versus specific oxoG base is occurring in the second step of the oxoG-substrate binding. This step requires energy consumption which is compensated by the positive entropy contribution. The third binding step is the final adjustment of the enzyme/substrate complex to achieve the catalytically competent state which is characterized by large endothermicity compensated by a significant increase of entropy originated from the dehydration of the DNA grooves.
Tris(2,3,5,6-tetrathiaaryl)methyl cations, which were generated from the corresponding triarylmethanols in the presence of strong acids, underwent reaction with nucleophiles to give trityl radicals, as the product of a one-electron reduction of the carbocation. Depending on the nature of the nucleophile, the only byproducts were either diamagnetic quinone methides or asymmetrical monosubstituted trityl radicals. Herein, we report a protocol for the large-scale synthesis of the Finland trityl, which has the advantage of high overall yield and reproducibility.
Classical knot theory can be generalized to virtual knot theory and spatial graph theory. In 2007, Fleming and Mellor combined virtual knot theory and spatial graph theory to form, combinatorially, virtual spatial graph theory.

In this paper, we introduce a topological definition of virtual spatial graphs that is similar to the topological definition of a virtual link. Our main goal is to generalize the classical Yamada polynomial that is defined for a spatial graph. We define a generalized Yamada polynomial for a virtual spatial graph and prove that it can be normalized to a rigid vertex isotopic invariant and to a pliable vertex isotopic invariant for graphs with maximum degree at most 3.

We consider the connection and difference between the generalized Yamada polynomial and the Dubrovnik polynomial of a classical link. The generalized Yamada polynomial specializes to a version of the Dubrovnik polynomial for virtual links such that it can be used to detect the non-classicality of some virtual links. We obtain a specialization for the generalized Yamada polynomial (via the Jones-Wenzl projector $P_2$ acting on a virtual spatial graph diagram), that can be used to write a program for calculating it based on Mathematica Code.
We have surveyed avian influenza virus (AIV) genomes from live poultry markets within China since 2014. Here we present a total of 16,091 samples that were collected from May 2016 to February 2019 in 23 provinces and municipalities in China. We identify 2048 AIV-positive samples and perform next generation sequencing. AIV-positive rates (12.73%) from samples had decreased substantially since 2016, compared to that during 2014–2016 (26.90%). Additionally, H9N2 has replaced H5N6 and H7N9 as the dominant AIV subtype in both chickens and ducks. Notably, novel reassortants and variants continually emerged and disseminated in avian populations, including H7N3, H9N9, H9N6 and H5N6 variants. Importantly, almost all of the H9 AIVs and many H7N9 and H6N2 strains prefer human-type receptors, posing an increased risk for human infections. In summary, our nation-wide surveillance highlights substantial changes in the circulation of AIVs since 2016, which greatly impacts the prevention and control of AIVs in China and worldwide.
These anomalies locate near the Selenginskaya depression on the eastern coast of Lake Baikal. Knowledge of the magnetic properties of rock massifs that are the sources of these anomalies is necessary to assess the magnetoelastic coefficients, which may be different for remanent and inductive magnetization.

The remanent magnetization, magnetic susceptibility and its anisotropy, as well as the Q factor of the samples of rocks, from the Zarechenskaya and Nikolskaya magnetic anomalies have been determined.

This, in turn, will make it possible to further increase the reliability of the interpretation of the results of tectomagnetic monitoring performed here.
One of the main difficulties in the formation and increase of revenues from hydrocarbon resources is the deterioration of the quality of the mineral resource base and changes in the geography of production. One can observe an increase in the depletion and water content of the fields, an increase in the proportion of highly viscous and high-sulfur oil; the share of stocks in hard-to-reach and infrastructural underdeveloped regions is growing. One of the tools for encouraging subsoil users to develop such resources is to ensure lower rates of deductions to state bodies.

The study presents an improved methodological approach to estimating and forecasting state budget revenues from hydrocarbon resources. The main stages of development are investigated and the main trends of the system of tax deductions from oil production are revealed. Explained the use of an approach focused on the forecast of production indicators of production, taking into account the structure of the mineral resource base.

The calculations showed the need to reform the system of formation of government revenues from hydrocarbon resources. In the structure of government revenues from hydrocarbon resources, there is a tendency to increase the role of the mineral extraction tax in comparison with the export duty.
The hypothesis of the gradual enhancement of small perturbations on an initially smooth initiating blast wave, traditionally used in the numerical simulation of multi-front detonation, does not agree with the experimental data.

A technique for determining the Q-value of mixture was proposed, based on reconstruction of the trajectory of the expanding wave from the position of the strong explosion model. The wave trajectory at the critical initiation of a multifront detonation in a combustible mixture is compared with the trajectory of an explosive wave from the same initiator in an inert mixture whose gas-dynamic parameters are equivalent to the parameters of the combustible mixture. The energy release of a mixture is defined as the difference in the joint energy release of the initiator and the fuel mixture during the critical initiation and energy release of the initiator when the blast wave is excited in an inert mixture.

The analysis of the initiation of a detonation wave (DW) and the emergence of a multi-front structure of the DW-front are presented. It is shown that the structure of the DW arises spontaneously at the stage of a strong overdriven of the wave. The instability of the DW is due to the chemical energy release of the combustible mixture Q. Observable deviations of the experimental profile of Q from existing model representations were found.
Endometrial carcinoma is the most common gynecologic malignancy which is associated with a poor prognosis when diagnosed at an advanced stage; therefore, the discovery of efficacious new drugs is required to reinforce conventional chemotherapy. Short-term cultures of primary cells from endometrial tumors could be used for testing new anticancer therapeutics as well as for the development of personalized cancer therapy strategy. Here, the antitumor effect of a recombinant analogue of lactaptin (RL2), a new potential anticancer molecule, was examined against primary human endometrial cancer cells.Primary cell cultures of malignant and normal human endometrium were performed by enzymatic digestion of endometrial tissue from biopsy material. Real-time quantitative reverse transcription polymerase chain reaction (RT-PCR) was performed to determine the messenger ribonucleic acid (mRNA) state of estrogen (ERs) and progesterone (PRs) hormone receptors and aromatase (Cyp 19) in cell cultures. Dynamic monitoring of cell adhesion and proliferation was made using the iCELLigence system (ASEA Biosciences). The sensitivity of cell cultures to conventional anticancer drugs and the lactaptin analog was estimated by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay, flow cytometry, and the iCELLligence system.Established short-term primary cultures of endometrial cancer cells were ERα/ERβ/PR-positive and sensitive for RL2. The IC 50 values of doxorubicin and cisplatin were determined for all of the primary cultures designed. KE normal cells displaying low Cyp19 mRNA levels and high ERβ and PR mRNA levels were more resistant to RL2 treatment as well as to cisplatin and doxorubicin.Our results indicate that the recombinant analog of lactaptin, RL2, exerts cytotoxic effects against primary hormone-dependent endometrial tumor cells in vitro with features of apoptosis.
Рассматриваются базовые условия формирования Аэротрополиса в районе аэропорта Толмачево Новосибирской области в сравнении с мировым опытом развития приаэропортовых урбанизированных районов.

Проанализирован социально-экономический потенциал муниципальных образований, включенных в зону новосибирского Аэротрополиса, выявлены резервы развития территории.

Выделены те направления развития территории вокруг аэропорта Толмачево, которые наиболее характерны для мировых тенденций развития подобных территорий: транспортная инфраструктура, объекты логистики, бизнес и медицинские центры, отели
A search for the process e + e − → D *0 (2007) has been performed with the CMD-3 detector at the VEPP-2000 e + e − -collider.

Two main decay modes of the D *0 (2007) decay, D 0 π 0 and D 0 γ, followed by D 0 → K + π − π + π − are used in this analysis. With an integrated luminosity of 3.7 pb −1 collected at the center-of-mass energy E c.m. =2006.62 MeV

our preliminary upper limit is B D* 0 → e + e − <1.6× 10 −6 at 90%C.L.
The last decade saw extensive studies of the human gut microbiome and its relationship to specific diseases, including gallstone disease (GSD). The information about the gut microbiome in GSD-afflicted Russian patients is scarce, despite the increasing GSD incidence worldwide. Although the gut microbiota was described in some GSD cohorts, little is known regarding the gut microbiome before and after cholecystectomy (CCE). By using Illumina MiSeq sequencing of 16S rRNA gene amplicons, we inventoried the fecal bacteriobiome composition and structure in GSD-afflicted females, seeking to reveal associations with age, BMI and some blood biochemistry. Overall, 11 bacterial phyla were identified, containing 916 operational taxonomic units (OTUs). The fecal bacteriobiome was dominated by Firmicutes (66% relative abundance), followed by Bacteroidetes (19%), Actinobacteria (8%) and Proteobacteria (4%) phyla. Most (97%) of the OTUs were minor or rare species with ≤1% relative abundance. Prevotella and Enterocossus were linked to blood bilirubin. Some taxa had differential pre- and post-CCE abundance, despite the very short time (1–3 days) elapsed after CCE. The detailed description of the bacteriobiome in pre-CCE female patients suggests bacterial foci for further research to elucidate the gut microbiota and GSD relationship and has potentially important biological and medical implications regarding gut bacteria involvement in the increased GSD incidence rate in females.
A series of micro-disperse Ni-Mo alloys with the sponge-like structure was prepared by a simultaneous precipitation method followed by sintering of the sediment in H2 atmosphere at 800 °C. According to XRD data, the formation of single-phase solid solution Ni1-xMox took place for the samples with Mo content of 0.6-8.3 wt.%.

Synthesized samples were studied in a process of the catalytic CVD of C2H4Cl2 at 550-700 °C. In situ kinetic studies of carbon deposition process were carried out in a flow gravimetric setup equipped with McBain balances. The impact of Mo concentration upon the morphology, structural features and textural properties of the produced carbon fibers was investigated by means of SEM, TEM, Raman spectroscopy and low-temperature nitrogen adsorption.

An interaction of Ni-Mo alloys with C2H4Cl2 is accompanied by their rapid disintegration with formation of disperse active particles catalyzing the growth of carbon nanomaterials (CNM). The strong boosting effect of Mo on the catalytic performance of Ni was revealed. The maximum yield of CNM product (8.3 wt.% Mo, 600 °C, 120 min) was as high as 45 g/gM. The study on effect of the reaction temperature on the CNM yield allowed one to define an optimal temperature regime. The role of chemisorbed chlorine species in a pulse-to-pulse regime of the segmented carbon filaments formation was discussed.
In this paper, for the first time, explicit solutions of a semi-Hamiltonian system of quasi-linear differential equations by the generalized hodograph method are found.These solutions define (local) metrics on a surface for which the geodesic flow has a polynomial in momenta integrals of the fourth degree.
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme involved in energy metabolism. Recently, GAPDH has been suggested to have extraglycolytic functions in DNA repair, but the underlying mechanism for the GAPDH response to DNA damage remains unclear.

Here, we demonstrate that the tyrosine kinase Src is activated under DNA damage stress and phosphorylates GAPDH at Tyr41. This phosphorylation of GAPDH is essential for its nuclear translocation and DNA repair function. Blocking the nuclear import of GAPDH by suppressing Src signaling or through a GAPDH Tyr41 mutation impairs its response to DNA damage. Nuclear GAPDH is recruited to DNA lesions and associates with DNA polymerase β (Pol β) to function in DNA repair.

Nuclear GAPDH promotes Pol β polymerase activity and increases base excision repair (BER) efficiency. Furthermore, GAPDH knockdown dramatically decreases BER efficiency and sensitizes cells to DNA damaging agents. Importantly, the knockdown of GAPDH in colon cancer SW480 cells and xenograft models effectively enhances their sensitivity to the chemotherapeutic drug 5-FU. In summary, our findings provide mechanistic insight into the new function of GAPDH in DNA repair and suggest a potential therapeutic target in chemotherapy.
This material belongs to the group of bismuth tellurohalides BiTeX (X = Cl,Br,I) which are layered non-centrosymmetric materials with strong spin–orbit interaction.

By angle-resolved photoemission spectroscopy (ARPES) we observe a giant Rashba-type spin splitting in the electronic bulk conduction and valence bands of the semiconductor BiTeCl. By photon energy-dependent ARPES, we separate the bulk and surface contribution of the electronic structure.

We show that the tellurium-terminated (0001) crystal surface hosts spin-split two-dimensional surface states. On the chlorine-terminated surface at the opposite side of the crystal no surface states are observed due to photon-induced surface chemistry.
The paper is devoted to the first application of the SPH-IDIC method to simulation of three-dimensional dusty gas flow. The expansion of a sphere consisting of gas and monodisperse fine dust into vacuum is considered as a model problem. Computing was carried out using graphic accelerators based on nVidia CUDA technology. The numerical simulations show ability of the method to deal with three-dimensional dynamics. We found that in 3D case the method kept all the advantages previously demonstrated on one-dimensional problems: robustness, efficiency and simplicity in implementation.
The paper summarizes the results of experiments on electron cyclotron emission (ECE) measurements recently performed at the GDT magnetic mirror device.

The new ECE diagnostics is installed to facilitate the successful ECRH experiment and operates in the vicinity of the ECRH frequency 54.5 GHz.

The particulars of plasma emission at the fundamental electron cyclotron harmonic are studied experimentally in a broad range of discharge scenarios.
The effect of the electroweak sphaleron transition in balance between baryon excess and and the excess of stable quarks of 4th generation is studied in this paper.

Considering the non-violation of $SU(2)$ symmetry and the conservation of electroweak and new charges and quantum numbers of the new family, it makes possible sphaleron transitions between baryons, leptons and 4th family of leptons and quarks. In this paper, we have tried to established a possible definite relationship between the value and sign of the 4th family excess relative to baryon asymmetry.

If $U$-type quarks are the lightest quarks of the 4th family and sphaleron transitions provide excessive $ar U$ antiquarks, asymmetric dark matter in the form of dark atom bound state of ($ar{U} ar{U} ar{U}$) with primordial He nuclei is balanced with baryon asymmetry.
Early diagnosis of rheumatoid arthritis (RA) is crucial to providing effective therapy and often hampered by unspecific clinical manifestations. Elevated levels of extracellular circulating DNA (cirDNA) in patients with autoimmune disease were found to be associated with etiopathogenesis.

To our knowledge, this is the first study to investigate the putative diagnostic use of cirDNA in RA and its association with disease activity. Blood samples were taken from 63 healthy subjects (HS) and 74 patients with RA. cirDNA was extracted from plasma and cell surface-bound cirDNA fractions (csbDNA). cirDNA concentration was measured by quantitative real-time polymerase chain reaction. Rheumatoid factor was analyzed by immunonephelometry, whereas C-reactive protein and anticitrullinated protein/peptide antibodies (ACPA) were detected by enzyme-linked immunosorbent assay.

Plasma cirDNA was significantly elevated in patients with RA compared with HS (12.0 versus 8.4 ng/ml, p < 0.01). In contrast, nuclear csbDNA (n-csbDNA) was significantly decreased (24.0 versus 50.8 ng/ml, p < 0.01), whereas mitochondrial csbDNA (m-csbDNA) was elevated (1.44 × 106 copies/ml versus 0.58 × 106 copies/ml, p < 0.05) in RA. The combination of csbDNA (mitochondrial + nuclear) with ACPA reveals the best positive/negative likelihood ratios (LRs) for the discrimination RA from HS (LR+ 61.00, LR− 0.03) in contrast to ACPA (LR+ 9.00, LR− 0.19) or csbDNA (LR+ 8.00, LR− 0.18) alone. Nuclear and mitochondrial cirDNA levels in plasma and on the surface of blood cells are modulated in RA. Combination of cirDNA values with ACPA can improve the serological diagnosis of RA.
The energy gap was revealed in the Dirac cone of the BiSbTeSe2 topological insulator after the submonolayer deposition of a ferromagnetic metal. As a ferromagnet, cobalt and manganese were used. Such way of the energy gap opening is novel in comparison to the bulk ferromagnetic doping of topological insulators.
A numerical model is constructed and dynamics of the cylindrical localized area of turbulent disturbances (turbulent spot) in a longitudinal horizontally homogeneous shear flow of a passive stratified fluid is studied.

The results of calculations show a significant turbulent energy generation by shear flow.

The problem of flow similarity with respect to the shear Froude number for sufficiently large values of this parameter is considered.