Hengzongshu/ArticleAgent huggingface dataset:
anomalous extraordinary transmission (ET) through subwavelength slit and hole arrays loaded by a dielectric slab

in-depth circuit analysis, analytical and numerical results together with experimental data

provides physical insight of the underlying mechanism governing anomalous ET and offers further independent control over orthogonal polarized waves impinging into subwavelength aperture arrays
Micrometric inclusions in platinum-group minerals (PGMs) from alluvial placers carry considerable information about types of primary rocks and ores, as well as conditions of their formation and alteration. In the present contribution, we attempt to show, with concrete examples, the significance of the data on the composition and morphology of micrometric inclusions to genetic interpretations. The PGM grains from alluvial placers of the Gornaya Shoria region (Siberia, Russia) were used as the subject of our investigation. In order to determine the chemical composition of such ultrafine inclusions, high-resolution analytical methods are needed. We compare the results acquired by wavelength-dispersive spectrometry (WDS; electron microprobe) and energy-dispersive spectrometry (EDS) and scanning electron microscopy (SEM) methods. The results obtained have good convergence. The EDS method is multi-elemental and more effective for mineral diagnostics in comparison with WDS, which is its certain advantage. The possible conditions for the formation of inclusions and layers of gold, sulfoarsenides and arsenides in Pt3Fe grains, which have an original sub-graphic and layered texture pattern, are discussed. They are the result of solid solution and eutectic decompositions and are associated with the magmatic stages of grain transformation, including the result of the interaction of Pt3Fe with a sulfide melt enriched with Te and As.
Objective. The aim of the systematic review was to find an answer to the question: «does an increased blood pressure affect kidney function at young age?». Design and methods. The following key words were used to search for relevant publications: “hypertensive nephropathy”, “reduction of glomerular filtration rate in arterial hypertension” in Russian and English. We used “eLIBRARY.RU — SCIENTIFIC ELECTRONIC LIBRARY” and PubMed.gov databases. The inclusion criteria were the young age of the examined patients (from 18 to 44 years), the absence of concomitant pathology. The analysis included only publications of the last 5 years (2015-2020). Results. A total of 18 articles were selected from Russian and international databases that meet inclusion criteria. Conclusions. Based on the analysis of the literature of the last 5 years we assume that increase in blood pressure disrupts kidney function in young people. However, the current data a number of limitations. Until now, gender characteristics, risk factors for decreased renal function in hypertension in young people, and most importantly, the pathogenetic basis of renal dysfunction remain unclear.
The complexes of Fe II and Co II with phthalocyanines are extremely good catalysts for oxidation of organic compounds with molecular oxygen and hydrogen peroxide.Their solubility and reactivity are increased by conjugation with oligonucleotides and by formation of dimeric complexes between negatively and positively charged phthalocyanines.In our work such complexes were formed directly on single-stranded DNA through interaction between negatively charged Co II phthalocyanine in conjugate and positively charged Fe II phthalocyanine in solution.The resulting oppositely charged phthalocyanine complexes showed significant increase of catalytic activity compared with monomeric forms of phthalocyanines Fe II .The site-directed modification of single-and double-stranded DNA by H 2 O 2 in the presence of dimeric complexes of negatively charged Co II and positively charged Fe II phthalocyanines was detected.These complexes catalyzed the DNA oxidation with high efficacy and led to direct DNA strand cleavage.
At the end of 2016 the SND detector resumed data taking at the upgraded VEPP-2000 e + e − collider. The analysis of data accumulated in 2010-2013 with an integrated lumonosity of 70 pb −1 is continuing. Recent results on measurements of various hadronic cross sections are presented.
The work is aimed at analyzing coordination mechanisms of corporate solutions and at studying a number of mechanisms, decision-making processes and information links with the use of hierarchical algorithms of block programming.

The work presents a routine task for high dimensional optimization adequate for the design of hierarchical systems of production companies and corporations, an objective function and a restriction system with composition-block structure. The special methods of block programming, where interaction between the center and the performers corresponds to the centralized and decentralized mechanisms of decision-making coordination in economic systems have been developed for this type of optimization problems. For the analysis of decision-making coordination in big systems, the unique classification of the mechanisms of decision-making coordination in hierarchical systems based on the level of information awareness of the center and the ways to increase this level has been applied.

It is shown that the convergence of the sequences of the specifying solutions of performers to an optimal decision-making for a system in general seems to be a necessary condition of institutional coordination methods.
Despite the progress achieved in target, chemo-, and radiotherapy, treatment options for patients with latestage metastatic castration-resistant prostate cancer are presently very limited.Use of dendritic cell-based vaccines exemplified by sipuleucel-T appears is rarely curative and is effective in only a fraction of such patients.Given the success of CAR T cell therapy in the field of B cell malignancies, significant efforts have been made to adapt this powerful technology to the problem of metastatic prostate cancer.Availability of unique prostate cancer surface targets for CAR T cells has thereby become a pressing issue in the field of CAR design.Ideally, such targets should be absent from normal cells or tissues, be present on all prostate cancer cells across all patients, and be indispensable for the survival of cancer cells.In reality, however, none of the prostate cancer-associated surface markers described to date are matching such description.Here, we catalogue the list of tested as well as prospective surface antigens to be used as targets for CAR T cell therapy, and discuss the aspects of their safety and potential efficacy.
The design of the large-aperture variable-period undulator (VPU) developed for the Novosibirsk free electron laser (FEL) is shortly described. High amplitude of on-axis field is achieved due to the arc shape of the magnet blocks and poles of the undulator. To conduct magnetic measurements and fine tuning of the undulator as well as to perform real time position tracking of magnet blocks, pulsed wire technique was adopted.
We give a classification of $5$- and $6$-dimensional complex one-generated nilpotent bicommutative algebras.
Current studies on bread wheat resistance to stem rust have two main subjects: complex analysis for resistance of bread wheat germplasm using molecular markers, field screening and laboratory tests against samples of different fungal populations, and searching for sources and donors of new genes and gene loci, including cultivated and wild relatives of wheat. To achieve adequate genetic control of the disease, an integral approach is important, incorporating both data on sources of resistance and relevant information on pathogenic populations existing in the region, their race composition and dynamics of virulence genes. The analysis of experimental data on field screening of bread wheat varieties from the CIMMYT nursery germplasm for stem rust resistance in the Omsk and Novosibirsk regions, together with laboratory testing of infection samples on the international set of wheat differential lines, suggests that a separate "Asian" population of Puccinia graminis f. sp. tritici exists in Western Siberia and the Altai Territory. Wheat resistance genes Sr2, Sr6Ai#2, Sr24, Sr25, Sr26, Sr31, Sr39, Sr40, Sr44, and Sr57 are of practical interest for advanced wheat breeding programs for stem rust immunity in Western Siberia. This review provides an analysis of the gene sources that remain effective against the West Siberian population of P. graminis, in order to facilitate the initial stage of selection of breeding material to develop a stable genotype by gene pyramiding. The basic requirements for conducting a phytopathological test of breeding material are presented. A list of molecular markers for the mentioned resistance genes, both widely used in marker-assisted selection and requiring verification, has been compiled.
In this contribution, a method based on a solid solution theory of clathrate hydrate for multiple cage occupancy, host lattice relaxation and guest-guest interactions has been presented to estimate hydrate formation conditions of binary and ternary gas mixtures. We have performed molecular modeling of structure, guest distribution, and hydrate formation conditions for the CO2 + CH4, and CO2 + CH4 + N2 gas hydrates. In all considered systems with and without N2, at high and medium content of CO2 in the gas phase we have found that CO2 is more favorable to occupy clathrate hydrate cavities than CH4 or N2. Addition of N2 to the gas phase increases ratio concentration CO2 in compressing with concentration CH4 in clathrate hydrates and makes gas replacement more effective. The mole fractions of CO2 in CO2 + CH4 + N2 gas hydrate rapidly increases with the growth of its content in the gas phase. And the formation pressure of CO2 + CH4 + N2 gas hydrate rises in comparison with the formation pressure of CO2 + CH4 gas hydrate. Obtained results agree with the known experimental data for simple CH4, CO2 gas hydrates and mixed CO2 + CH4 gas hydrate.
ФГФОУ высшего образования «Новосибирский национальный исследовательский государственный университет», Новосибирск В.М.Маракулин ФГФОУ высшего образования «Новосибирский национальный исследовательский государственный университет»; Институт математики им.С.Л.Соболева СО РАН, Новосибирск Аксиоматизация вектора Шепли в играх с априорными вероятностями образования коалиций Аннотация.Вводится и изучается новая, обобщенная модель кооперативной игры с трансферабельной полезностью (ТП-игра), в которой кроме характеристической функции используются две дополнительные функции: отношений между игроками и вероятности образования коалиций, которые отражают основные черты взаимодействия людей в конкретных группах.Изучаются различные свойства функции вероятности и доказано, какие из них являются достаточными для ее трансформации в вероятностную меру.Обобщенный вектор Шепли определяется для нового класса игр как математическое ожидание игрока от его маргинального вклада в коалиции.Приведены необходимые и достаточные условия, чтобы обобщенный вектор Шепли полностью совпадал с классическим, введенным Шепли
Mechanical treatment of dry powder mixtures has often been reported to give new compounds. The assumption of neat mechanochemical conditions must, however, be made with caution even if the reactants are not crystal hydrates. The fluidised intermediate, which is often necessary for mechano-co-crystallisation of organic molecules, can readily form by interaction with atmospheric moisture. We illustrate this using "dry" mechanochemical synthesis of glycinium semi-malonate as an example. The α-glycine and malonic acid mixture is shown to be highly hygroscopic, which can be largely accredited to the hygroscopicity of malonic acid. Dissolution in atmospheric moisture is sufficient for the spontaneous crystallisation of the salt product. This is a prime example where liquid is both necessary for mechanosynthesis, while simultaneously hindering the reaction by affecting the rheology of the mixture: Liquid Hindered Grinding. These results shed new light on possible sources of regional, seasonal and temperature effects on mechanosynthesis, as well as a potential role for polymer additives.
This study presents a taxonomical review of the species Pseudolamarckina pseudorjasanensis Dain, 1967 collected at different sampling levels from the central and northern parts of European Russia and from Western Siberia. Morphological and biometrical analyses show that P. pseudorjasanensis is characterized by wide intraspecific variabilities and may encompass various previously described Kimmeridgian species of the genus Pseudolamarckina. The first appearance of P. pseudorjasanensis is recorded from the latest Early Kimmeridgian of sub-Mediterranean to Arctic regions. Furthermore, P. pseudorjasanensis appears to be the marker species of the foraminiferal JF41 Zone in Kimmeridgian sections of sub-boreal, boreal and Arctic regions. This JF41 Zone is particularly significant for interregional correlations. Finally, P. pseudorjasanensis was widespread across the Kimmeridgian basins of the Northern Hemisphere and was associated with environments predominantly located in the middle sublittoral zone.
The Russian farm-fox experiment is an unusually long-running and well-controlled study designed to replicate wolf-to-dog domestication. As such, it offers an unprecedented window onto the neural mechanisms governing the evolution of behavior. Here we report evolved changes to gray matter morphology resulting from selection for tameness versus aggressive responses toward humans in a sample of 30 male fox brains. Contrasting with standing ideas on the effects of domestication on brain size, tame foxes did not show reduced brain volume. Rather, gray matter volume in both the tame and aggressive strains was increased relative to conventional farm foxes bred without deliberate selection on behavior. Furthermore, tame- and aggressive-enlarged regions overlapped substantially, including portions of motor, somatosensory, and prefrontal cortex, amygdala, hippocampus, and cerebellum. We also observed differential morphologic covariation across distributed gray matter networks. In one prefrontal-cerebellum network, this covariation differentiated the three populations along the tame-aggressive behavioral axis. Surprisingly, a prefrontal-hypothalamic network differentiated the tame and aggressive foxes together from the conventional strain. These findings indicate that selection for opposite behaviors can influence brain morphology in a similar way. SIGNIFICANCE STATEMENT Domestication represents one of the largest and most rapid evolutionary shifts of life on earth. However, its neural correlates are largely unknown. Here we report the neuroanatomical consequences of selective breeding for tameness or aggression in the seminal Russian farm-fox experiment. Compared with a population of conventional farm-bred control foxes, tame foxes show neuroanatomical changes in the PFC and hypothalamus, paralleling wolf-to-dog shifts. Surprisingly, though, aggressive foxes also show similar changes. Moreover, both strains show increased gray matter volume relative to controls. These results indicate that similar brain adaptations can result from selection for opposite behavior, that existing ideas of brain changes in domestication may need revision, and that significant neuroanatomical change can evolve very quickly, within the span of <100 generations.
Ozone is a very effective medical, industrial and agricultural disinfector, bleacher and deodorizer. Ozone acts very quickly, but its decay rate is also high. Gas hydrate formation is a promising method for storing ozone and ozone-containing gas mixtures. We use molecular dynamics (conjugate gradient) and lattice dynamics method to calculate the free energy double O 3 +CO 2 hydrate of cubic structure I at 270 K and 275 K temperatures and various gas phase compositions. It allowed determining the chemical potential of water molecules depending on pressure at given temperatures and compositions. Comparison with Ih ice and liquid water allowed us to determine regions of O 3 +CO 2 double hydrate stability. The presented results may be useful in studies of thermodynamic stability areas of hydrates obtained from pure ozone (e.g. liquid ozone), its mixtures and in the development of corresponding storage technologies.
Fine structural details of glycans attached to the conserved N-glycosylation site significantly not only affect function of individual immunoglobulin G (IgG) molecules but also mediate inflammation at the systemic level.

By analyzing IgG glycosylation in 5,117 individuals from four European populations, we have revealed very complex patterns of changes in IgG glycosylation with age.

Several IgG glycans (including FA2B, FA2G2, and FA2BG2) changed considerably with age and the combination of these three glycans can explain up to 58% of variance in chronological age, significantly more than other markers of biological age like telomere lengths. The remaining variance in these glycans strongly correlated with physiological parameters associated with biological age. Thus, IgG glycosylation appears to be closely linked with both chronological and biological ages. Considering the important role of IgG glycans in inflammation, and because the observed changes with age promote inflammation, changes in IgG glycosylation also seem to represent a factor contributing to aging.
We have shown for the first time that simple annealing of silver–synthetic diamond mixtures in air or oxygen at 600–700 °C leads to selective growth of silver particles on the {100} facets of diamond

Annealing at a temperature higher than 750 °C results in significant morphological changes in the heterostructure: silver particles grow not only on the cube but also on the octahedral facets.
The present study aimed to analyze possible associations of rs7412 and rs429358 of the APOE gene with lipid profile parameters, the risk of myocardial infarction, and death in the mostly white population of Western Siberia (Russia). The study population was selected from a sample surveyed within the framework of the Health, Alcohol and Psychosocial Factors In Eastern Europe (HAPIEE) study (9360 subjects, age 53.8 ± 7.0 years, males/females 50/50).

PCR was conducted with fluorescence detection according to the TaqMan principle on a real-time PCR machine. The frequency of a minor allele (C) of rs429358 was 0.13, and the frequency of a minor allele (T) of rs7412 was 0.09. In our study, the woman with the rare ɛ1/ɛ4 genotype had substantial aberrations in blood lipid levels. In Kaplan-Meier curves, statistically significant differences were revealed in the prognosis of survival within the subgroup of females who had a myocardial infarction (p = 0.0006): the prognosis was worse for carriers of the ɛ2/ɛ2 genotype and for ɛ4/ɛ4 carriers. Survival analysis regarding deaths from all causes showed (p = 0.0238) that female carriers of the ɛ2/ɛ4 genotype had a worse prognosis than did carriers of other genotypes.

Thus, in the population of Western Siberia (Russia), we confirmed statistically significant associations between rs7412 & rs429358 genotypes and lipid profile parameters.
Antibodies (Abs) containing two different antigen-binding sites in one molecule are called bispecific. Bispecific Abs (BsAbs) were first described in the 1960s, the first monoclonal BsAbs were generated in the 1980s by hybridoma technology, and the first article describing the therapeutic use of BsAbs was published in 1992, but the number of papers devoted to BsAbs has increased significantly in the last 10 years. Particular interest in BsAbs is due to their therapeutic use. In the last decade, two BsAbs – catumaxomab in 2009 and blinatumomab in 2014, were approved for therapeutic use.

Papers published in recent years have been devoted to various methods of BsAb generation by genetic engineering and chemical conjugation, and describe preclinical and clinical trials of these drugs in a variety of diseases.

This review considers diverse BsAb-production methods, describes features of therapeutic BsAbs approved for medical use, and summarizes the prospects of practical application of promising new BsAbs.
Water, plasmas, and laser light can all exhibit instabilities.

Experiments in two different areas of wave physics are used to investigate the creation and annihilation dynamics of superregular breather waves, which combine to form an instability.

superregular breather waves combine to form an instability.
We perform Large-eddy simulations (LES) of an annular swirling turbulent jet. The swirl parameter is considered within the range S = 0.3−0.6. The Reynolds number based on the bulk velocity and outer pipe diameter is 8900 while the outer to inner diameter ratio is 2. We obtain different flow regimes without and with the vortex breakdown occurring for S = 0.4. Coherent vortical structures for each regime are indentified using the azimuthal Fourier decomposition and the Proper orthogonal decomposition (POD). The turbulent kinetic energy accumulates in the first POD modes with the azimuthal number m = 1.
A set of algorithms and procedures of a crystal loop centering during X-ray high-throughput protein crystallography experiment has been designed and developed.

A simple algorithm of the crystal loop detection and preliminary recognition has been designed and developed. The crystal loop detection algorithm is based on finding out the crystal loop ending point (opposite to the crystal loop pin) using image cross section (digital image column) profile analysis. The crystal loop preliminary recognition procedure is based on finding out the crystal loop sizes and position using image cross section profile analysis. The crystal loop fine recognition procedure based on Hooke-Jeeves pattern search method with an ellipse as a fitting pattern has been designed and developed. The procedure of restoring missing coordinate of the crystal loop is described. Based on developed algorithms and procedures the optimal auto-centering procedure has been designed and developed. A procedure of optimal manual crystal centering (Two Clicks Procedure) has been designed and developed.

Developed procedures have been integrated into control software system PCCS installed at crystallography beamlines Photon Factory BL5A and PF-AR NW12, KEK.
In this study, the development and characterization of composite sorbents based on commercial mesoporous silica gels and LiCl for seasonal thermal energy storage (STES) applications is described. The reported activity aims at validating the operation of sorption STES in various cold climatic zones in Europe. Accordingly, the reference boundary conditions were identified by means of a climatic analysis in two climatic zones, namely, Central and Northern Europe. The acquired mesoporous silica gels were characterized, to evaluate the textural properties, i.e. specific pore volume and pore size, needed to define the optimal salt solution compositions to maximize the amount of salt embedded. The synthesized samples were firstly investigated using scanning electron microscopy and nitrogen physisorption that demonstrate the presence of a small quantity of salt over the external surface rather than inside the pores. A hydrothermal treatment, based on slow adsorption followed by a slow desorption step, was defined to solve this issue. Finally, starting from the measured equilibrium isobars, the expected STES density at material level was evaluated, obtaining values as high as 1080 J/g under cold Northern European climatic condition, corresponding to 650 MJ/m3.