Hengzongshu/ArticleAgent huggingface dataset:
We introduce an extension to the Protege ontology editor, which allows for discovering concept definitions, which are not explicitly present in axioms, but are logically implied by an ontology. The plugin supports ontologies formulated in the Description Logic EL, which underpins the OWL 2 EL profile of the Web Ontology Language and despite its limited expressiveness captures most of the biomedical ontologies published on the Web. The developed tool allows to verify whether a concept can be defined using a vocabulary of interest specified by a user. In particular, it allows to decide whether some vocabulary items can be omitted in a formulation of a complex concept. The corresponding definitions are presented to the user and are provided with explanations generated by an ontology reasoner.
Numerous publications of Russian and Mongolian researchers report the only species Fragaria orientalis Losinsk to be typical for Mongolia. However, by generally accepted taxonomy of Fragaria genus, the species F. orientalis is a tetraploid (2 n =4 x =28) which occupies a small area within Eastern regions of Russia and North-Western China.

To clarify the specific belonging of strawberry, 11 Fragaria samples were collected in Central, Northern and Eastern parts of Mongolia. Species were identified by morphological characters and molecular marker of alcohol dehydrogenase adh1 gene.

The results of the specific belonging study in Fragaria samples reveal two diploid species F. viridis and F. mandshrica growing in Mongolia.
Let [Formula: see text] be a short exact sequence of Lie algebras over a field [Formula: see text], where [Formula: see text] is abelian.

We show that the obstruction for a pair of automorphisms in [Formula: see text] to be induced by an automorphism in [Formula: see text] lies in the Lie algebra cohomology [Formula: see text]. We also obtain a more explicit necessary and sufficient condition for a pair of automorphisms in [Formula: see text] to be induced by an automorphism in [Formula: see text], where [Formula: see text] is a free nilpotent Lie algebra of rank [Formula: see text] and step [Formula: see text].

As a consequence, we obtain a four term exact sequence relating automorphisms, derivations and cohomology of Lie algebras.
We report the first measurement of the $T$-odd moments in the decay ${D}^{0}\ensuremath{\rightarrow}{K}_{S}^{0}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\pi}}^{0}$ from a data sample corresponding to an integrated luminosity of $966\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ collected by the Belle experiment at the KEKB asymmetric-energy ${e}^{+}{e}^{\ensuremath{-}}$ collider. From these moments we determine the $CP$-violation-sensitive asymmetry ${a}_{CP}^{T\text{-odd}}=[\ensuremath{-}0.28\ifmmode\pm\else\textpm\fi{}1.38(\mathrm{stat}.{)}_{\ensuremath{-}0.76}^{+0.23}(\mathrm{syst}.)]\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}3}$, which is consistent with no $CP$ violation. In addition, we perform ${a}_{CP}^{T\text{\ensuremath{-}}\mathrm{odd}}$ measurements in different regions of the ${D}^{0}\ensuremath{\rightarrow}{K}_{S}^{0}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\pi}}^{0}$ phase space; these are also consistent with no $CP$ violation.
PD is a neurodegenerative disease characterized with loss of dopamine neurons and associated with neuroinflamation and unbalanced in HPA-axis. We investigated the content of cortisol and DEAS - hormones of HPA-axis in patients with PD after applying rTMS. Feng S.F. et al. (2012) showed that rTMS improves the balance of HPA axis hormones during depression, which is one of the non-motor manifestations of PD. PD patients were randomized into groups with active rTMS (13 men, 11 women) and sham rTMS (10 men, 15 women).The 10Hz rTMS was performed sequentially over 2 targets: the primary motor cortex and the DLPFC daily for 20 days. Outcome measures included the indicators of MDS-UPDRS (Part 3) scale, content of cоrtisol and DEAS in the peripheral blood.The Motor Examination Part scores demonstrated clinically meaningful improvement only in the active treatment group (p < 0.01). The content of the DEAS in this group was negatively correlated with indicators of scales of clinical manifestations, stress and anxiety (p < 0.05). In this group an increase of content of DEAS in the peripheral blood of men was found (p < 0.01, Wald-Wolfowitz Runs Test). Thus, the rTMS increases the levels of a wellknown neuroprotective hormone and a modulator of DA activity DEAS only in men.
A novel and convenient approach for the solid-phase 5'-functionalization of oligonucleotides is proposed in this article. The approach is based on the activation of free 5'-hydroxyl of polymer support-bound protected oligonucleotides by N,N'-disuccinimidyl carbonate followed by interaction with amino-containing ligands. Novel amino-containing derivatives of closo-dodecaborate, estrone, cholesterol, and α-tocopherol were specially prepared. A wide range of oligonucleotide conjugates bearing closo-dodecaborate, short peptide, pyrene, lipophilic residues (cholesterol, α-tocopherol, folate, estrone), aliphatic diamines, and propargylamine were synthesized and characterized to demonstrate the versatility of the approach. The developed method is suitable for the conjugate synthesis of oligonucleotides of different types (ribo-, deoxyribo-, 2'-O-methylribo-, and others).
The discovery of the Higgs boson (and still nothing else) have triggered appearance of many proposals of Higgs factories for precision measurement of the Higgs properties. Among them there are several projects of photon colliders (PC) without e+e− in addition to PLC based on e+e− linear colliders ILC and CLIC.

In this paper, following a brief discussion of Higgs factories physics program I give an overview of photon colliders based on linear colliders ILC and CLIC,

and of the recently proposed photon-collider Higgs factories with no e+e− collision option based on recirculation linacs in ring tunnels.
The results of using an adapted sampling algorithm by the Monte Carlo method to estimate the ambiguity domain of the inversion of synthetic dispersion curves of the phase velocities of surface waves using artificial neural networks are discussed in the paper.

The expediency of using the considered algorithm for calculating a probabilistic estimate of the results of the inverse problem solution in the method of multichannel analysis of surface waves

has been confirmed.
Juvenile hormone (JH) and dopamine are involved in the stress response in insects. The insulin/insulin-like growth factor signalling pathway has also recently been found to be involved in the regulation of various processes, including stress tolerance. However, the relationships among the JH, dopamine and insulin signalling pathways remain unclear.

Here, we study the role of insulin signalling in the regulation of JH and dopamine metabolism under normal and heat stress conditions in Drosophila melanogaster females. We show that suppression of the insulin-like receptor (InR) in the corpus allatum, a specialised endocrine gland that synthesises JH, causes an increase in dopamine level and JH-hydrolysing activity and alters the activities of enzymes that produce as well as those that degrade dopamine (alkaline phosphatase (ALP), tyrosine hydroxylase (TH) and dopamine-dependent arylalkylamine N-acetyltransferase (DAT)). We also found that InR suppression in the corpus allatum modulates dopamine, ALP, TH and JH-hydrolysing activity in response to heat stress and that it decreases the fecundity of the flies. JH application restores dopamine metabolism and fecundity in females with decreased InR expression in the corpus allatum.

Our data provide evidence that the insulin/insulin-like growth factor signalling pathway regulates dopamine metabolism in females of D. melanogaster via the system of JH metabolism and that it affects the development of the neuroendocrine stress reaction and interacts with JH in the control of reproduction in this species.
The concept of a major inhibitory role of serotonin in aggressive behavior is widely accepted by investigators. There was ample evidence that a pharmacologically-induced increase in the serotonin activity attenuates agonistic behavior in animals, and that the manipulations inhibiting the brain serotonergic system can elicit aggressiveness in male mice and rats. Repeated experience of aggression in daily agonistic interactions has been shown to reduce serotonin activity in brain of victorious male mice. The study aimed to analyze expression of the serotonergic genes -Tph2, Sert, Maoa and Htr1a, as well as the Bdnf and Creb genes in the midbrain raphe nuclei of male mice with positive fighting experience in daily encounters and male mice with the same track record of aggression followed by two-week no-fight period. It has been shown that mRNA levels of the serotonergic and Creb genes are reduced in the winners in comparison with male mice without consecutive positive fighting experience of aggression. After the fighting deprivation the Tph2, Sert, Bdnf and Creb genes recover their expression while mRNA levels of the Maoa and Htr1a genes proceed at a significantly higher level as compared with the respective controls. Downregulation of serotonergic genes is indicative of the inhibition of serotonergic activity under repeated experience of aggression. Nevertheless recovering of Tph2 and Sert gene expression and overexpression of the Maoa and Htr1a genes after no-fight period suggest that changes in brain serotonergic activity are not main cause of the behavioral pathology developing in male mice in this experimental context.
Second order cylindrical surfaces, i.e., elliptic, hyperbolic, and parabolic cylinders serve as examples of such manifolds for the tree-dimensional space (the phase space is two-dimensional).

The aim of the paper is the construction and numerical solution of stochastic differential equations whose trajectories are located on a given smooth manifold with probability 1. Classes of stochastic differential equations are constructed for these surfaces and linear equations with multiplicative noise are marked in these classes.

The results of modelling were used to estimate the deviations of numerical solutions from the manifold. A comparative analysis of considered examples was carried out for accuracy of eight numerical solution methods for stochastic differential equations.
Hyperpolarized gases revolutionize functional pulmonary imaging. Hyperpolarized propane is a promising emerging contrast agent for pulmonary MRI. Unlike hyperpolarized noble gases, proton‐hyperpolarized propane gas can be imaged using conventional MRI scanners with proton imaging capability. Moreover, it is non‐toxic odorless anesthetic.

Furthermore, propane hyperpolarization can be accomplished by pairwise addition of parahydrogen to propylene. Here, we demonstrate the feasibility of propane hyperpolarization via hydrogenation of cyclopropane with parahydrogen. 1 H propane polarization up to 2.4 % is demonstrated here using 82 % parahydrogen enrichment and heterogeneous Rh/TiO 2 hydrogenation catalyst.

This level of polarization is several times greater than that obtained with propylene as a precursor under the same conditions despite the fact that direct pairwise addition of parahydrogen to cyclopropane may also lead to formation of propane with NMR‐invisible hyperpolarization due to magnetic equivalence of nascent parahydrogen protons in two CH 3 groups. NMR‐visible hyperpolarized propane demonstrated here can be formed only via a reaction pathway involving cleavage of at least one C–H bond in the reactant molecule. The resulting NMR signal enhancement of hyperpolarized propane was sufficient for 2D gradient echo MRI of ∼5.5 mL phantom with 1×1 mm 2 spatial resolution and 64×64 imaging matrix despite relatively low chemical conversion of cyclopropane substrate.
The heat flux distribution near the contact lines of one or several (3) drops on a horizontal heated constantan foil is investigated. The temperature distribution of the bottom foil surface was measured by the FLIR infrared (IR) camera. To measure the heat flux distribution near the contact lines numerical solution of the Cauchy problem is used. The maximum of the heat flux density is observed near the contact line and it exceeds the average heat flux density by several times. This is due to relatively high heat conductivity coefficient of the foil material and high evaporation rate in the contact line region, so the heat flux from the foil periphery (out of the drop) is enter to the contact line region of the drop.
ВЫЯВЛЕНИЕ УЧАСТКОВ ДНК, СПЕЦИФИЧНЫХ ДЛЯ РЕГУЛЯТОРНЫХ РАЙОНОВ КОНТРОЛИРУЕМЫХ ГЛЮКОКОРТИКОИДАМИ ГЕНОВ, МЕТОДОМ КОМПЬЮТЕРНОГО АНАЛИЗА Т. И
The paper aims to show the importance of reasoning “from metaphysics” in the course of a consistent interpretation of the “against neoscholasticism” thesis (J. Ladyman). The idea that “the subject of metaphysics is metaphysical possibilities, and science determines which of them are actually achieved” (E. J. Lowe, J. Katz, etc.) reinforces the role of reasoning “from metaphysics” within the field of metaphysics of science. The general theory of relativity violates the common prevailing intuition that “causality is the subject of local physical interaction” (J. Bigelow). Interpretation of causality in terms of “forces” and “coming into” within the framework of E. J. Lowe's ontology makes it possible to talk about causality in terms of “finding” and “going out” of existence of the corresponding modes of objects connected by a formal “causal relationship”. The transition to E. J. Lowe's ontology helps not only to overcome the intuition of the locality of causality, but also reveals in its own way, for example, such seemingly simple common intuitions as the dependence of the truth of propositions on time or the understanding of time as a dimension. All this once again brings us back to the understanding of the importance of the fact that a scientist, constructing or interpreting a scientific theory, as a rule, uses non-trivial philosophical assumptions that should be the subject of its own philosophical analysis.
Avian influenza viruses (AIVs) are maintained in wild bird reservoirs, particularly in mallard ducks and other waterfowl. Novel evolutionary lineages of AIV that arise through genetic drift or reassortment can spread with wild bird migrations to new regions, infect a wide variety of resident bird species, and spillover to domestic poultry. The vast continental reservoir of AIVs in Eurasia harbors a wide diversity of influenza subtypes, including both highly pathogenic (HP) and low pathogenic (LP) H7 AIV. The Caspian Sea region is positioned at the intersection of major migratory flyways connecting Central Asia, Europe, the Black and Mediterranean Sea regions and Africa and holds a rich wetland and avian ecology. To understand genetic reservoirs present in the Caspian Sea region, we collected 559 cloacal swabs from Anseriformes and other species during the annual autumn migration periods in 2017 and 2018. We isolated two novel H7N3 LPAIV from mallard ducks whose H7 hemagglutinin (HA) gene was phylogenetically related to contemporaneous strains from distant Mongolia, and more closely Georgia and Ukraine, and predated the spread of this H7 LPAIV sublineage into East Asia in 2019. The N3 neuraminidase gene and internal genes were prototypical of AIV widely dispersed in wild bird reservoirs sampled along flyways connected to the Caspian region. The polymerase and nucleoprotein segments clustered with contemporaneous H5 HPAI (clade 2.3.4.4b) isolates, suggesting the wide dispersal of H7 LPAIV and the potential of this subtype for reassortment. These findings highlight the need for deeper surveillance of AIV in wild birds to better understand the extent of infection spread and evolution along spatial and temporal flyways in Eurasia.
A new one-dimensional kinematic model of viscous fingers growth is proposed. This model is based on the assumption of an intermediate layer formation. The shear instability of the flow is developed in this layer due to intensive mixing of liquids of different viscosities. The thickness of the intermediate layer between outer ones is determined by the velocity difference in the layers. The results of the calculation of the growth rate of the fingers in the framework of this model are in a good agreement with the calculations carried out on the basis of more general two-dimensional equations as well as with the known Koval model.
We report the formation and phase separation response of nickel-graphite composites with variable-architecture phases by graphitization-accompanied consolidation via Spark Plasma Sintering and hot pressing. It was shown that the application of pressure during consolidation is crucial for the occurrence of graphitization and formation of 3D graphite structures. We evaluated the suitability of the synthesized composites as precursors for making porous structures. Nickel behaved as a space holder with the particle size and spatial distribution changing during consolidation with the temperature and determining the structure of porous graphite formed by phase separation by dissolution in HCl. The response of the consolidated Ni-Cgr to separation of carbon by its burnout in air was studied. The result of the carbon removal was either the formation of a dense and continuous NiO film on the surface of the compacts or oxidation through the compact thickness. The choice between these two options depended on the density of the compacts and on the presence of carbon dissolved in nickel. It was found that during the burnout of graphite from Ni-Cgr composites, sintering, rather than formation of pores, dominated.
Recent work shows that MFST very accurately predicts the formation of coherent structures in turbulent shear flows, such as the PVC. MFST may further reveal the flow regions that are most susceptible to flow actuation to suppress the PVC, which is of great practical relevance.

In this work we employ mean field stability theory (MFST) to predict the onset of the precessing vortex core (PVC) in the draft tube of Francis turbines. MFST is based on the linear stability analysis of the mean field of turbulent flows. In this work, MFST is accompanied by a data-driven approach to predict the linear growth rate of the PVC based on pointwise wall pressure measurements. The method is based on statistical evaluation of the probability density function of the PVC amplitude at limit cycle. It makes use of the intense noise induced by the background turbulence, which is expected to be a major driver of hydrodynamic instabilities.

The empirical and analytic results are compared to phase-locked LDV measurements conducted inside the draft tube at various operating conditions, to assess the quantitative accuracy of the approach. The methodologies outlined in this work will be of relevance for future design of hydro turbines to run stable over a wide range of operating conditions.
Understanding the principles and mechanisms of cell growth coordination in plant tissue remains an outstanding challenge for modern developmental biology. Cell-based modeling is a widely used technique for studying the geometric and topological features of plant tissue morphology during growth. We developed a quasi-one-dimensional model of unidirectional growth of a tissue layer in a linear leaf blade that takes cell autonomous growth mode into account. The model allows for fitting of the visible cell length using the experimental cell length distribution along the longitudinal axis of a wheat leaf epidermis. Additionally, it describes changes in turgor and osmotic pressures for each cell in the growing tissue. Our numerical experiments show that the pressures in the cell change over the cell cycle, and in symplastically growing tissue, they vary from cell to cell and strongly depend on the leaf growing zone to which the cells belong. Therefore, we believe that the mechanical signals generated by pressures are important to consider in simulations of tissue growth as possible targets for molecular genetic regulators of individual cell growth.
We present the first direct search for lepton flavour violating muon decay mediated by a new light particle X, $$\upmu ^+ \rightarrow \mathrm {e}^+\mathrm {X}, \mathrm {X} \rightarrow \upgamma \upgamma \ $$ μ + → e + X , X → γ γ . This search uses a dataset resulting from $$7.5\times 10^{14}$$ 7.5 × 10 14 stopped muons collected by the MEG experiment at the Paul Scherrer Institut in the period 2009–2013. No significant excess is found in the mass region 20–45 MeV/c $$^2$$ 2 for lifetimes below 40 ps, and we set the most stringent branching ratio upper limits in the mass region of 20–40 MeV/c $$^2$$ 2 , down to $${\mathcal {O}}(10^{-11})$$ O ( 10 - 11 ) at 90% confidence level.
A genetic locus suppressing DNA underreplication in intercalary heterochromatin (IH) and pericentric heterochromatin (PH) of the polytene chromosomes of Drosophila melanogaster salivary glands, has been described. Found in the In(1)sc V2 strain, the mutation, designated as Su(UR)ES , was located on chromosome 3L at position 34.8 and cytologically mapped to region 68A3-B4. A cytological phenotype was observed in the salivary gland chromosomes of larvae homozygous and hemizygous for Su(UR)ES : ( i ) in the IH regions, that normally are incompletely polytenized and so they often break to form “weak points,” underreplication is suppressed, breaks and ectopic contacts disappear; ( ii ) the degree of polytenization in PH grows higher. That is why the regions in chromosome arm basements, normally β-heterochromatic, acquire a distinct banding pattern, i.e., become euchromatic by morphological criteria; ( iii ) an additional bulk of polytenized material arises between the arms of chromosome 3 to form a fragment with a typical banding pattern. Chromosome 2 PH reveals additional α-heterochromatin. Su(UR)ES does not affect the viability, fertility, or morphological characters of the imago, and has semidominant expression in the heterozygote and distinct maternal effect. The results obtained provide evidence that the processes leading to DNA underreplication in IH and PH are affected by the same genetic mechanism.
We get a new proof that hyperspace {(x, y, t) | t > 0} of canonical Heisenberg group H 1 satisfies inner and outer continuously deformable cc-homogeneous cone conditions and cc-uniformity condition.By means of that we prove that hyperspace {(x, y, t, z) | t > 0} of canonical Engel group E α,β satisfies inner and outer continuously deformable cc-homogeneous cone conditions.
The conventional Friedmann cosmology is known to be in tension with the existence of stable particles having interaction strength typical for supersymmetry and heavier than several TeV.

A possible way to save life of such particles may be a modification of the standard cosmological expansion law in such a way that the density of these heavy relics would be significantly reduced. We study particle creation in the Starobinsky inflationary model for different decay channels of the scalaron.

It is shown that in the process of thermalization superheavy stable particles with the coupling strength typical for the GUT SUSY could be created with the density equal to the observed density of dark matter.
An annotated list of 29 species from 18 genera and 10 families of Trichoptera inhabiting rivers and streams of the Mountainous Shoria is given. All species are recorded from this region for the first time. Two species, Dicosmoecus obscuripennis Banks, 1938 and Rhyacophila lata Martynov, 1918, are new for Western Siberia. Moreover, Mountainous Shoria is the westernmost locality for Rhyacophila narvae Navas, 1926, Neophylax ussuriensis (Martynov, 1914), and Stenopsyche griseipennis (McLachlan, 1866) distribution.