Hengzongshu/ArticleAgent huggingface dataset:
2 МГУ им.М.В.Ломоносова, Москва; 3 ГИН РАН, Москва; 4 ПИН им.А.А.Борисяка РАН, Москва 5 ИНГГ СО РАН, Новосибирск; 6 НГУ, Новосибирск Пðèвîдèòñя дåòàëьíîå îпèñàíèå ðàзðåзà ñðåдíåюðñкèх òåððèãåííых îòëîжåíèй íà ð.Яðåíãå (Àðхàíãåëьñкàя îбëàñòь) -íîвîãî ìåñòîíàхîждåíèя îñòàòкîв ìîðñкèх ðåпòèëèй.Сðåдè íàхîдîк пðåîбëàдàюò пîñòкðàíèàëьíыå эëåìåíòы ñкåëåòà íåñкîëькèх îñîбåй пëåзèîзàвðà Muraenosaurus
A method of imaging of ultra-fast processes, like explosion or fast combustion, at a synchrotron radiation beam is being developed at the Siberian Synchrotron and Teraherz Radiation Center (SSTRC). Two stations are operating at beam line 0 at the VEPP-3 storage ring and at beam line 8 at the VEPP-4M storage ring. Both stations are equipped with the detector for imaging of explosions DIMEX, based on high pressure ionization chamber, and allowing to record up to 100 one-dimensional images with the frame rate of 8 MHz. However, the maximum flux that DIMEX can detect is limited as well as spatial resolution and frame rate because of gas technology used.

In view of significant increase of SR flux at the VEPP-4M beam line due to the new 9-pole 2 T wiggler, a new detector is being developed for this beam line, based on Si microstrip sensor. The first Si microstrip detector prototype has been mounted with new specially developed front-end ASIC that allows to record data with the rate of 50 MFrames/s.

The first measurements with this prototype demonstrated significant improvement of all critical parameters of the detector compared to the gaseous version. The maximum detected photon rate before saturation is increased to ∼10000 photons/(chan x bunch) compared to ∼1000 photons/(chan x bunch) (Si detector has 50 µm channel pitch while gaseous detector has 100 µm channel pitch). Spatial resolution is improved from 250 µm to 72 µm and frame rate is increased by a factor more than 6.
The aim of the work is to investigate the parameters of hemostasis, electrical and viscoelastic parameters of red blood cells and markers of inflammation in persons suffering from arterial hypertension to determine the possibility of assessing the severity of hemorheological disorders.

Material and methods. The study included 203 patients (156 patients with arterial hypertension and 47 patients without hypertension). The parameters of hemostasis, markers of inflammation and red blood cells were studied.

The study of the parameters of hemostasis, markers of inflammation, red blood cells allowed us to determine the key indicators for assessing the severity of hemorheological disorders in patients with arterial hypertension.
Bone samples from two individuals (an adult and a child) buried at a Middle Bronze Age cemetery Bertek-56 on the Ukok Plateau, Altai, were subjected to a genetic analysis. The results are interpreted with reference to archaeological and craniometric data.

Four systems of genetic markers were analyzed: mitochondrial DNA, the polymorphic part of amelogenin gene, autosomal STR-loci, and STR-loci of Y-chromosome. Complete information on these genetic markers was obtained for the adult individual. For the child, data on mitochondrial DNA, amelogenin gene, and partial profiles of autosomal and Y-chromosomal STR-loci are available. Both individuals were shown to be male and unrelated. The boy's mitochondrial DNA belongs to the Western Eurasian haplogroup K (subgroup K1a24a), and that of the adult male, to the Eastern Eurasian haplogroup C. Using the predictor program, the Y-chromosomal haplotype of the adult individual (17 Y-chromosomal STR-loci) was identified as Eastern Eurasian haplogroup Q.

Phylogenetic and phylogeographic analysis of the results suggests that the Bertek population originated from an admixture of two genetically contrasting groups, one with Eastern Eurasian, the other with Western Eurasian features. These results are consistent with those of the archaeological and craniometric analysis indicating the admixture of autochthonous groups with immigrants from western Eurasia.
El Grupo de Asha de los Urales meridionales, inicialmente definido por Albert Olli como complejo sedimentario paleozoico, hace más de medio siglo, fue considerado como una sección clave para el Véndico (Ediacárico) de la vertiente occidental de los Urales meridionales. Sin embargo, secuencia sedimentaria terrígena de unos 1.700 m de espesor se caracteriza por una biodiversidad inusualmente baja de macrofósiles ediacaranos, lo que podría explicarse por la edad relativamente temprana del grupo y el posible evento de extinción masiva que marca el final del período Ediacárico. La edad relativamente temprana fue confirmada por la datación de 547.6±3.8 Ma obtenida de una toba en la parte inferior de la Formación de Basa, así como por el hallazgo de la iconospecie Didymaulichnus tirasensis en la parte superior de la Formación de Zigan. Sin embargo, en 2018 se ha documentó la aparición masiva de D. tirasensis en la parte más baja de la Formación de Basa. Por lo tanto, la edad Véndico (Ediacárico) del Grupo de Asha de los Urales meridionales puede ser reconsiderada en favor del Ediacárico terminal-Cámbrico o incluso del Cambrian temprano.
For the first time, derivatives of 3,7-diazabicyclo[3.3.1]nonane (bispidine) were proposed as potential inhibitors of the SARS-CoV-2 main viral protease (3-chymotrypsin-like, 3CLpro).

Based on the created pharmacophore model of the active site of the protease, a group of compounds were modeled and tested for activity against 3CLpro. The 3CLpro activity was measured using the fluorogenic substrate Dabcyl-VNSTLQSGLRK(FAM)MA; the efficiency of the proposed approach was confirmed by comparison with literature data for ebselen and disulfiram.

The results of the experiments performed with bispidine compounds showed that 14 compounds exhibited activity in the concentration range 1-10 μM, and 3 samples exhibited submicromolar activity. The structure-activity relationship studies showed that the molecules containing a carbonyl group in the ninth position of the bicycle exhibited the maximum activity. Based on the experimental and theoretical results obtained, further directions for the development of this topic were proposed.
We report on the observation of the lateral electric spin polarization effect in a suspended GaAs-based quantum point contact (QPC) separated from the substrate.

The effect manifests itself in the experiment as the appearance of an additional half-integer plateaus at 0.5×2e2/h when the asymmetric voltage is applied to the side gates in zero magnetic field. The appearance of the plateaus has been attributed to the spin degeneracy lifting caused by the spin-orbit coupling associated with the lateral electric field in the asymmetrically biased QPC.

We have experimentally demonstrated that, despite the relatively small g-factor in GaAs, the observation of the spin polarization in the GaAs-based QPCs becomes possible after the suspension due to the enhancement of the electron-electron interaction and the effect of the electric field guiding. These features are caused by a partial confinement of the electric field lines within a suspended semiconductor layer with a high dielectric constant.
ABSTRACT It was evidenced, that the increase in the prevalence of autosomal recessive deafness 1A (DFNB1A) in populations of European descent was promoted by assortative marriages among deaf people. Assortative marriages become possible with a widespread introduction of sign language resulting in increased the genetic fitness of deaf individuals, thus relaxing selection against deafness. Currently, cochlear implantation is becoming a common method of rehabilitation for deaf patients, restoring their hearing ability and promoting the acquirement of spoken language. Whether the mass cochlear implantation could affect the spread of hereditary deafness is unknown. We have developed an agent-based computer model for analysis of the spread of DFNB1A. Using the model, we tested impact of different intensity of selection pressure on an isolated human population for 400 years. The modeling of the “purifying” selection pressure on deafness resulted in decrease of the proportion of deaf individuals and the pathogenic allele frequency. The modeling of relaxed selection resulted in increase of the proportion of deaf individuals and the decrease of the pathogenic allele frequency. The results of neutral selection pressure modeling showed no significant changes in both the proportion of deaf individuals and the pathogenic allele frequency after 400 years. Thus, initially low genetic fitness of deaf people can be significantly increased in the presence of assortative mating by deafness, resulting in a higher prevalence of DFNB1A. Contrary, frequency of pathogenic allele and the incidence of hereditary hearing loss will not increase in a population where all deaf individuals undergo cochlear implantation.
A Re(IV) cluster complex [Re(3)(μ(3)-S)(μ-S)(3)(dppe)(3)Br(3)](+) with nine cluster skeletal electrons (CSE) and a quadruplet ground state has been prepared by treatment of [Re(3)S(7)Br(6)]Br with 1,2-bis(diphenylphosphino)ethane (dppe) in MeCN.
Technical solutions of the concept exploration device SMOLA for longitudinal plasma flow suppression in linear plasma trap by active plasma pumping in helicoidal magnetic field are described in the article. Vacuum system, magnetic system, plasma source and the source of the radial electric field are discussed.
A search for the electroweak production of charginos, neutralinos and sleptons decaying into final states involving two or three electrons or muons is presented. The analysis is based on 36.1 fb -1 of s=13 TeV proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider.

Several scenarios based on simplified models are considered. These include the associated production of the next-to-lightest neutralino and the lightest chargino, followed by their decays into final states with leptons and the lightest neutralino via either sleptons or Standard Model gauge bosons; direct production of chargino pairs, which in turn decay into leptons and the lightest neutralino via intermediate sleptons; and slepton pair production, where each slepton decays directly into the lightest neutralino and a lepton.

No significant deviations from the Standard Model expectation are observed and stringent limits at 95% confidence level are placed on the masses of relevant supersymmetric particles in each of these scenarios. For a massless lightest neutralino, masses up to 580 GeV are excluded for the associated production of the next-to-lightest neutralino and the lightest chargino, assuming gauge-boson mediated decays, whereas for slepton-pair production masses up to 500 GeV are excluded assuming three generations of mass-degenerate sleptons.
Introduction of reporter groups at designed RNA sites is a widely accepted approach to gain information about the molecular environment of RNAs in their complexes with other biopolymers formed during various cellular processes.

A general approach to obtain RNAs bearing diverse reporter groups at designed locations is based on site-specific insertion of groups containing primary aliphatic amine functions (amino linkers) with their subsequent selective derivatization by appropriate chemicals. This article is a brief review on methods for site-specific introduction of amino linkers in different RNAs. These methods comprise: (i) incorporation of a nucleoside carrying an amino-linker or a function that can be substituted with it into oligoribonucleotides in the course of their chemical synthesis; (ii) assembly of amino linker-containing RNAs from short synthetic fragments via their ligation; (iii) synthesis of amino linker-modified RNAs using T7 RNA polymerase; (iv) insertion of amino linkers into unmodified RNAs at functional groups of a certain type such as the 5'-phosphates and N7 of guanosine residues and (v) introduction of an amino linker into long highly structured RNAs exploiting an approach based on sequence-specific modification of nucleic acids.

Particular reporter groups used for derivatization of amino linker-containing RNAs together with types of RNA derivatives obtained and fields of their application are presented.
Advances in genetic tools applied to livestock breeding has prompted research into the previously neglected breeds adapted to harsh local environments. One such group is the Welsh mountain sheep breeds, which can be farmed at altitudes of 300 m above sea level but are considered to have a low productive value because of their poor wool quality and small carcass size. This is contrary to the lowland breeds which are more suited to wool and meat production qualities, but do not fare well on upland pasture.

Herein, medium-density genotyping data from 317 individuals representing 15 Welsh sheep breeds were used alongside the whole-genome resequencing data of 14 breeds from the same set to scan for the signatures of selection and candidate genetic variants using haplotype- and SNP-based approaches.

Haplotype-based selection scan performed on the genotyping data pointed to a strong selection in the regions of GBA3, PPARGC1A, APOB, and PPP1R16B genes in the upland breeds, and RNF24, PANK2, and MUC15 in the lowland breeds. SNP-based selection scan performed on the resequencing data pointed to the missense mutations under putative selection relating to a local adaptation in the upland breeds with functions such as angiogenesis (VASH1), anti-oxidation (RWDD1), cell stress (HSPA5), membrane transport (ABCA13 and SLC22A7), and insulin signaling (PTPN1 and GIGFY1). By contrast, genes containing candidate missense mutations in the lowland breeds are related to cell cycle (CDK5RAP2), cell adhesion (CDHR3), and coat color (MC1R). We found new variants in genes with potentially functional consequences to the adaptation of local sheep to their environments in Wales. Knowledge of these variations is important for improving the adaptative qualities of UK and world sheep breeds through a marker-assisted selection.
The article analyzes homo dignus («a worthy person») as a theoretical, constitutional and legal concept; secular and theological approaches to understanding human dignity, differences between the Roman concept of «dignitas» and the theological concept of «image of God» («imago Dei»); the problem of constitutional-legal and wider legal regulation of human dignity in the domestic and international context is investigated. The author notes that the legal concept of an individual interacts with the legal concept of human dignity and the forms of their interaction are diverse. 1) The dignity of the individual is the legal basis for the structure and elements of the legal status of man and citizen; 2) a person possesses dignity in the case of his full legal capacity, and in the case of limited or lost legal capacity; 3) the dignity is possessed by a person who can have various relations with the state: a stateless person, a citizen, a bipatride or a polypatride, an alien in the territory of the state; 4) the idea of dignity and the idea of equality, combining in the field of law, stimulate the generation of a new paradigmatic thinking in the form of equal dignity. This article substantiates the concept of «constitutionalism of human dignity» from the standpoint of the Russian, comparative and international context. The article uses methods of discursive and comparative legal analysis, the method of constitutional design, specific historical and formal legal methods of analysis. It is concluded that a complex constitutional legal institution of the personhood dignity has been gradually forming in Russia. This institution is a constitutional and legal innovation in the structure of the foundations of the legal status of a person and citizen
In some cases, the drilling of oil and gas wells requires support for the drilling process, which consists in monitoring the parameters and making urgent decisions. Accompanying drilling takes place using the existing communication channels between the office and drilling. Satellite and mobile communications are most common. They are characterized by a low speed of receiving and transmitting data, frequent disconnects, the use of NAT. As part of this work, a software tool has been developed for transparent access to drilling parameters and measurements while drilling from a telemetry system in order to organize remote tracking via existing communication channels, taking their limitations into account. The software was based on the implementation of the SSH protocol, which provided compression and encryption of the transmitted data and transparent access to TCP services at the rig. This makes it possible to use existing software to access drilling measurements, which makes it possible to reduce the amount of data transferred in comparison with remote desktops. The software has been tested in conditions close to the field, and has shown its suitability for solving the tasks it was designed for.
This article presents the results of the genesis investigation of Ni-and Mo-based dispersed steamcracking catalyst produced via in-situ heavy oil emulsion decomposition.The structural characteristics of catalysts and their precursors have been studied by SAXS and TEM for the first time at all stages of production and operation: in reverse emulsions, dispersions and in the coke residues obtained after catalytic steam cracking process It is shown that the Ni-based precursor is converted to larger aggregates during transition from a dispersion in heavy oil to Ni 9 S 8 10-40 nm particles in the coke residue.In the case of molybdenum this trend was not revealed, after steam cracking process two types of particles are formed: small layered MoS 2 particles with a length of 10-15 nm and larger MoO 2 20-30 nm particles.
In most mammalian cell lines, chromatin located at the nuclear periphery is represented by condensed heterochromatin, as evidenced by microscopy observations and DamID mapping of lamina-associated domains (LADs) enriched in dimethylated Lys9 of histone H3 (H3K9me2). However, in Kc167 cell culture, the only Drosophilla cell type where LADs have previously been mapped, they are neither H3K9me2-enriched nor overlapped with the domains of heterochromatin protein 1a (HP1a).

Here, using cell type-specific DamID we mapped genome-wide LADs, HP1a and Polycomb (Pc) domains from the central brain, Repo-positive glia, Elav-positive neurons and the fat body of Drosophila third instar larvae.

Strikingly, contrary to Kc167 cells of embryonic origin, in neurons and, to a lesser extent, in glia and the fat body, HP1a domains appear to overlap strongly with LADs in both the chromosome arms and pericentromeric regions. Accordingly, centromeres reside closer to the nuclear lamina in neurons than in Kc167 cells. As expected, active gene promoters are mostly not present in LADs, HP1a and Pc domains. These domains are occupied by silent or weakly expressed genes with genes residing in the HP1a-bound LADs expressed at the lowest level. In various differentiated Drosophila cell types, we discovered the existence of peripheral heterochromatin, similar to that observed in mammals. Our findings support the model that peripheral heterochromatin matures enhancing the repression of unwanted genes as cells terminally differentiate.
The paper deals with the problem of the structure of detonation waves in the silane-air mixture within the framework of mathematical model of a nonequilibrium gas dynamics. Detailed kinetic scheme of silane oxidation as well as the newly developed reduced kinetic model of detonation combustion of silane are used. On its basis the detonation wave (DW) structure in stoichiometric silane - air mixture and dependences of Chapman-Jouguet parameters of mixture on stoichiometric ratio between the fuel (silane) and an oxidizer (air) were obtained.
The article is devoted to evaluating the applicability of SLAM frameworks for the task of mobile robots of the Duckietown project. The paper provides a comparative analysis of existing SLAM algorithms and frameworks and se-lects frameworks taking into account all the constraints imposed by the project robots. The practical results of testing OpenVSLAM framework on the Duckietown environment and Duckietown simulator data are presented.
Институт археологии и этнографии СО РАН Новосибирский государственный университет
We proposed and tested a method of experimental determination of the upper limit of RF resonator axis inclination to the beam axis.

The electric field transverse component by such a perturbation deflects the particle trajectory.

In the horizontal plane, a distortion of the closed orbit leads to a difference in the energies and spin precession frequencies of electrons and positrons in a storage collider with a single ring.
Inna Safonova, Shigenori Maruyama, Nikolai Kruk, Olga Obut, Pavel Kotler, Olga Gavryushkina, Sergey Khromykh, Maxim Kuibida, Sergey Krivonogov. Episodes 2018;41:79-88. https://doi.org/10.18814/epiiugs/2018/018008
Ferromagnetic materials are the widely used source of spin-polarized electrons in spintronic devices, which are controlled by external magnetic fields or spin-transfer torque methods. However, with increasing demand for smaller and faster spintronic components utilization of spin–orbit phenomena provides promising alternatives. New materials with unique spin textures are highly desirable since all-electric creation and control of spin polarization is expected where the strength, as well as an arbitrary orientation of the polarization, can be defined without the use of a magnetic field. In this work, we use a novel spin–orbit crystal BiTeBr for this purpose. Because of its giant Rashba spin splitting, bulk spin polarization is created at room temperature by an electric current. Integrating BiTeBr crystal into graphene-based spin valve devices, we demonstrate for the first time that it acts as a current-controlled spin injector, opening new avenues for future spintronic applications in integrated circuits.
One of the most fascinating problems in comparative psychology is how learning contributes to solving specific functional problems in animal life, and which forms of learning our species shares with non-human animals.

Simulating a natural situation of territorial conflicts between predatory carabids and red wood ants in field and laboratory experiments, we have revealed a relatively simple and quite natural form of learning that has been overlooked. We call it catalog learning, the name we give to the ability of animals to establish associations between stimuli and coherent behavioral patterns (patterns consist of elementary motor acts that have a fixed order). Instead of budgeting their motor acts gradually, from chaotic to rational sequences in order to learn something new, which is characteristic for a conditioning response, animals seem to be 'cataloguing' their repertoire of innate coherent behavioral patterns in order to optimize their response to a certain repetitive event. This form of learning can be described as 'stimulus-pattern' learning. In our experiments four 'wild' carabid species, whose cognitive abilities have never been studied before, modified their behavior in a rather natural manner in order to avoid damage from aggressive ants. Beetles learned to select the relevant coherent behavioral patterns from the set of seven patterns, which are common to all four species and apparently innate.

We suggest that this form of learning differs from the known forms of associative learning, and speculate that it is quite universal and can be present in a wide variety of species, both invertebrate and vertebrate. This study suggests a new link between the concepts of cognition and innateness.
The experimental study of an isothermal swirl flow with the formation of a precessing vortex core in the radial swirler upon non-confinement and confinement conditions is carried out.

Velocity profiles are obtained with varying Re and guide vane angle, changing the swirl number S . Four acoustic sensors and LDA system are used to measure Strouhal number as the function of the integral swirl number in the range from 0.5 < S <0.8.

It is shown that the unsteady flow with PVC effect significantly changes upon non-confinement and confinement conditions.