Hengzongshu/ArticleAgent huggingface dataset:
A highly transparent passivating contact (TPC) as front contact for crystalline silicon (c-Si) solar cells could in principle combine high conductivity, excellent surface passivation and high optical transparency. However, the simultaneous optimization of these features remains challenging. Here, we present a TPC consisting of a silicon-oxide tunnel layer followed by two layers of hydrogenated nanocrystalline silicon carbide (nc-SiC:H(n)) deposited at different temperatures and a sputtered indium tin oxide (ITO) layer (c-Si(n)/SiO 2 /nc-SiC:H(n)/ITO). While the wide band gap of nc-SiC:H(n) ensures high optical transparency, the double layer design enables good passivation and high conductivity translating into an improved short-circuit current density (40.87 mA cm −2 ), fill factor (80.9%) and efficiency of 23.99 ± 0.29% (certified). Additionally, this contact avoids the need for additional hydrogenation or high-temperature postdeposition annealing steps. We investigate the passivation mechanism and working principle of the TPC and provide a loss analysis based on numerical simulations outlining pathways towards conversion efficiencies of 26%.
The paper presents a recent progress in experimental studies and status of numerical simulations of the mirror based fusion neutron source developed by the Budker Institute of Nuclear Physics (Novosibirsk, Russia)

developed by the Budker Institute of Nuclear Physics

and its possible applications including a fusion material test facility and a fusion-fission hybrid system. Current research activity is supported by the Russian Science Foundation (project N 14-50-00080).
The features of near-threshold mode of initiating by gas-tight piston and high-enthalpy gas flow was evaluated for a powder density explosive PETN.

In this work, the effect of the gas flow on the mode of initiation was studied experimentally. The synchrotron radiation diagnostics have shown that the initial stages of the process were significantly different, that diversity being caused by the influence of the gas flow in the pores of the charge.

Both methods lead to the development of detonation in about 10 μs time.
The language of German Mennonites, referred to as Plautdietsch (self-designation Plotdich), or Mennonitenplatt, has a complex mixed character due to the history of its speakers. Through the centuries changing their place of residence, Mennonites, representatives of a special ethno-confessional community, now live in various countries of North and South America, European countries, and Russia.

This work aims at identifying and describing the articulatory characteristics of the labial-labial and labial-dental consonant phonemes of the language of the Mennonite Germans of Siberia by distributive analysis and magnetic resonance imaging. For the first time, the description of its phonemic composition is carried out using the methods of experimental phonetics. The research material was collected from two native speakers (Neudachino, Novosibirsk region). Twenty tomograms were described and analyzed using the methodology of the Laboratory of Experimental Phonetic Research named after V. M. Nadelyaev, Institute of Philology, SB RAS. The tomography program comprised eleven word forms, with the target sound in the initial and final positions.

Following N. S. Trubetskoy’s rules of phoneme selection, sound analysis identified five labial phonemes: noisy labial-labial mouth-bowed / p/ and / b/, noisy labial-dental mouth-slotted /v/ and /f/ and sonorous nasal-bowed /m/. Also, the analysis of MRI images determined the constitutive-differential features characteristic of the phonetic subsystem of labial consonantism of Plautdietsch.
Swirl flow with the formation of a precessing vortex core (PVC) in a hydro turbine draft tube model was studied using Stereo-PIV and four acoustic sensors. Experiments were performed on an aerodynamic setup in a wide range of operating conditions of the hydro turbine. Using a spatial Fourier decomposition of pressure pulsation data obtained from four acoustic sensors, a PVC was observed for part-load operating regimes (0.3-0.7 Q c ). Mean flow features were shown for the range of operating regimes from a deep part-load regime (0.3 Q c ) to an overload regime (1.5 Q c ). Based on phase-averaged velocity distributions, the PVC spatial structure was identified for maximum pressure pulsations on the cone walls of the draft tube.
The paper describes a method for processing microimages of thermochemical laser-induced periodic surface structures (TLIPSS) to quantify their structural order and defects.

Results of its application for the analysis of microimages of periodic structures formed in 30-nm chromium films by an astigmatically focused femtosecond Gaussian laser beam have been presented.

Dependences of the relative area of the beam-modified region, the area of defects, and the ordering of the periodic structures on the scanning speed and the writing beam power have been obtained.
We calculate the effect of variation in the light-current quark mass, mq, on standard big bang nucleosynthesis. A change in mq at during the era of nucleosynthesis affects nuclear reaction rates, and hence primordial abundances, via changes the binding energies of light nuclei.

It is found that a relative variation of δmq/mq = 0.016 ± 0.005 provides better agreement between observed primordial abundances and those predicted by theory. This is largely due to resolution of the existing discrepancies for 7Li. However this method ignores possible changes in the position of resonances in nuclear reactions. The predicted 7Li abundance has a strong dependence on the cross-section of the resonant reactions 3He (d, p) 4He and t (d, n) 4He.

We show that changes in mq at the time of BBN could shift the position of these resonances away from the Gamow window and lead to an increased production of 7Li, exacerbating the lithium problem.
Background. The first-generation trk inhibitors, larotrectinib and entrectinib, were approved by the u.s. Food and drug administration (Fda) for the treatment of advanced solid tumors harboring NTRK gene fusions in November 2018 and in august 2019, respectively. The purpose of the study was to present upto-date data on the structure and functions of ntrk genes, the frequency of occurrence of rearrangements with their participation, the consequences of their occurrence at the cellular level, methods of detecting such rearrangements, as well as targeted drugs used in the presence of chimeric NTRK genes.

Material and methods. A systemic literature search was conducted in pubmed ncbi, Web of science, scopus databases.

Results. The products of NTRK genes are receptors for neurotrophins, and their high expression is normally observed only in a narrow range of tissue types. Intrachromosomal or interchromosomal rearrangements lead to a significant increase in the level of expression of the chimeric gene regulated by the strong promoter of the partner gene. The high transcriptional activity of such a gene, along with the constant activation of the kinase activity of the protein product, leads to the activation of metabolic pathways responsible for cell escape from apoptosis and disruption of the regulation of the cell cycle. The occurrence of chimeric NTRK genes varies between different types of tumors, with the highest (up to 90 %) in rare cancers (secretory carcinoma of the breast, secretory carcinoma of the salivary glands, congenital mesoblastic nephroma, children’s fibrosarcoma). Larotrectinib and entrectinib are highly effective targeted drugs in suppressing the growth of a tumor carrying NTRK rearrangements, regardless of the type of tumor. In this regard, the introduction of new high-precision methods for the detection of chimeric NTRK genes, as well as the study of the mechanisms of the development of resistance with the assumption of ways to overcome it, seems relevant. Conclusion. Rearrangements of NTRK genes are quite common in various types of oncology and are an effective target for modern targeted drugs.
Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. Fibroblast growth factor 21 (FGF21) is a promising antiobesity agent, but its effects on melanocortin obesity are unknown. Sex is an important biological variable that must be considered when conducting preclinical studies; however, in laboratory animal models, the pharmacological effects of FGF21 are well documented only for male mice.

We aimed at investigating whether FGF21 affects metabolism in male and female mice with the lethal yellow (A y ) mutation, which results in MC4R blockage and obesity development. Obese C57Bl-A y male and female mice were administered subcutaneously for 10 days with vehicle or FGF21 (1 mg per 1 kg). Food intake (FI), body weight (BW), blood parameters, and gene expression in the liver, muscles, brown adipose tissue, subcutaneous and visceral white adipose tissues, and hypothalamus were measured.

FGF21 action strongly depended on the sex of the animals. In the males, FGF21 decreased BW and insulin blood levels without affecting FI. In the females, FGF21 increased FI and liver weight, but did not affect BW. In control A y -mice, expression of genes involved in lipid and glucose metabolism ( Ppargc1a, Cpt1, Pck1, G6p, Slc2a2 ) in the liver and genes involved in lipogenesis ( Pparg, Lpl, Slc2a4 ) in visceral adipose tissue was higher in females than in males, and FGF21 administration inhibited the expression of these genes in females. FGF21 administration decreased hypothalamic POMC mRNA only in males. Thus, the pharmacological effect of FGF21 were significantly different in male and female A y -mice; unlike males, females were resistant to catabolic effects of FGF21.
Background The naked caryopsis character in barley is a domestication-associated trait defined by loss-of-function of the NUD gene. The functional NUD gene encodes an Apetala 2/Ethylene-Response Factor (AP2/ERF) controlling the formation of a cementing layer between pericarp and both lemma and palea. The downstream genes regulated by the NUD transcription factor and molecular mechanism of a cementing layer formation are still not sufficiently described. A naturally occurring 17-kb deletion in the nud locus is associated with the emergence of naked barley. Naked barley has been traditionally used for food and nowadays is considered as a dietary component for functional nutrition.

Results In the present study, we demonstrate that targeted knockout of the NUD gene using RNA-guided Cas9 endonuclease leads to the phenotype conversion from hulled to naked barley. Using in vivo pre-testing systems, highly effective guide RNAs targeting the first exon of the NUD gene were selected. Expression cassettes harboring the cas9 and guide RNA genes were used to transform barley cv. Golden Promise via Agrobacterium -mediated DNA transfer. The recessive naked grain phenotype was observed in 57% of primary transformants, which indicates a frequent occurrence of homozygous or biallelic mutations. T-DNA-free homozygous lines with independently generated mutations in the NUD gene were obtained in the T1 generation. At homozygous state, all obtained mutations including one- and two-amino acid losses with the translational reading frame being retained invariably caused the naked grain phenotype.

Conclusions The hulled and naked barley isogenic lines generated are a perfect experimental model for further studies on pleiotropic consequences of nud mutations on overall plant performance under particular consideration of yield-determining traits. Due to the high β-glucan content of its grains, naked barley is considered as being of particular dietary value. The possibility to convert hulled into naked barley cultivars by targeted mutagenesis allows breeders to extend the potential utilization of barley by the provision of functional food.
Investigation of high frequency external perturbation effect on flow inside T-shape microchannel was examined.

In-phase pulsations of different frequencies were added to both inlets of the T-shaped microchannel to study mixing by means of Micro Laser Induced Fluorescence (μLIF) technique.

For all flow regimes studied, mixing enhancement was obtained. Significant enhancement can be achieved at the beginning of the outlet channel operating in steady asymmetric regime (Re=186) by forcing at certain frequency ranges (f = 500Hz, f = 800Hz). Mixing suppression was also observed for two flow regimes (Re = 400, f = 1000Hz) and (Re = 120, f = 700Hz).
In this paper, we give a short survey of recent results on the algebraic version of the Birkhoff conjecture for integrable billiards on surfaces of constant curvature. We also discuss integrable magnetic billiards.

As a new application of the algebraic technique, we study the existence of polynomial integrals for the two-sided magnetic billiards introduced by Kozlov and Polikarpov.

This article is part of the theme issue 'Finite dimensional integrable systems: new trends and methods'.
The Belle experiment, running at the KEKB e+e− asymmetric energy collider during the first decade of the century, achieved its original objective of precisely measuring differences between particles and antiparticles in the B system. After collecting 1000 fb−1 of data at various Υ resonances, Belle also obtained the many other physics results described in this article.
ПОГРЕБЕНИЯ ЗНАТИ В БОХАЕ И СИЛЛА: К ВОПРОСУ О ПЕРИОДЕ ГОСУДАРСТВ СЕВЕРА И ЮГА В КОРЕЙСКОЙ ИСТОРИОГРАФИИ К концу VII в. на Корейском полуострове и Южной Маньчжурии сложилась ситуация, когда государствами с общей границей оказались Силла и Бохай.Эта ситуация продолжалась в течении двух веков.В корейской историографии этот период называют «эпоха государств севера и юга», подразумевая наличие общности между двумя государствами.Однако между Силла и Бохаем были сильны культурные различия.Об этом свидетельствует погребальная обрядность элиты двух государств.В Бохая и Силла погребальные сооружения правителей существенно отличилась.Термин «эпоха государств севера и юга» закрепился в корейской историографии, однако вряд ли стоит перенимать опыт его использования для обозначения эпохи, начавшейся после завершения периода Трех государств в Корее.
The aim of the study was to investigate the association of single-nucleotide polymorphism (SNP) rs10507391 (A>T) with the acute cerebrovascular accident (CVA) development in patients of the East Siberian population with cardiovascular pathology and its risk factors.

Material and methods. The study involved 260 patients with acute CVA (age [57.0; 51.0–62.0]) and 272 patients of the control group (age [55.0; 51.0–62.0]). Among the patients who had acute CVA there were 157 men and 103 women. The control group included 170 men and 102 women. The examination of the experimental group included: collection of complaints, anamnesis, clinical examination, computed tomography of the brain, electrocardiography, echocardioscopy, ultrasound duplex scanning of extracranial brachiocephalic arteries, daily blood pressure and heart rate monitoring, and analysis of the blood coagulation system. In patients of the experimental group, the following cardiovascular pathology and risk factors were present: arterial hypertension, paroxysmal supraventricular tachycardias, dyslipidemia, atherosclerosis of the brachiocephalic arteries, and disorders of the hemostatic system. The control group was surveyed in the framework of the international “HAPIEE” project. Molecular genetic research was performed by real-time PCR. Statistical processing of the material was carried out using the following software: Statistica for Windows 7.0, Excel and SPSS 22.

Results. When studying the association of SNP rs10507391 (A>T) with the acute CVA development in all the analyzed groups and subgroups of patients, a link was established between the rare TT genotype and the T allele and an increased risk of acute CVA. Conclusion. TT genotype and T allele of the SNP rs10507391 (A>T) increase the risk of acute CVA in patients regardless of previous cardiovascular pathology and its risk factors, including patients with arterial hypertension, supraventricular tachyarrhythmias, atherosclerosis of brachiocephalic arteries, impaired lipid metabolism and hemostasis system.
We experimentally demonstrate Kerr beam self-cleaning of picosecond pulses in the anomalous dispersion regime of graded-index multimode optical fibers, with threshold power reduced by two orders of magnitude with respect to the normal dispersion regime.
China’s strong economic growth is undoubtedly due to a set of government initiatives, among which the priority projects are the reform of the higher education system. Since the 80s of the last century, the state has paid special attention to the training of scientific personnel. Thanks to far-sighted state planning and strong budget financing, China has created a competitive national system of postgraduate professional education almost from scratch.

Therefore, this article focuses on the organization of the learning process in Chinese universities and academic institutes, as well as the management mechanism of the national system of training scientific personnel. In addition, according to the data of China's Ministry of education, official statistical information, publications that are publicly available on the Chinese Internet, as well as scientific articles published in major publications around the world, it is shown how the number of universities and academic institutions that train masters and doctoral students, as well as the number of students, admission and graduation of specialists have changed over the past ten years.

As a result, if only 9 postgraduate students were trained in 1978, then in 1985 – already 17004, in 1998 – 47077, and in 2018 – 604368. The number of doctorates degrees awarded from 2005 to 2018 more than doubled: from 27,677 to 60,700. The important factors in the formation of the system of postgraduate education is the promulgation of national laws and regulations governing this area of educational activity, a well-built mechanism for managing the work of postgraduate studies and a strict system to control all stages of the educational process for masters and doctoral students.
In the present work we have studied the dispersion of single-walled carbon nanotubes in liquid crystalline asymmetrically substituted phthalocyanines (MPc, where M [Formula: see text] Cu, Co, and 2H) bearing one pyrene and six polyoxy groups as side chains.

The influence of single-walled carbon nanotubes on the phase behavior of MPcs was investigated using X-ray diffraction, polarized optical microscopy and differential scanning calorimetry.

It was demonstrated that the incorporation of small amounts of single-walled carbon nanotubes ([Formula: see text]1 wt.%) does not alter the MPc mesophases. The structural features and the sensor response of composite thin films of MPc with single-walled carbon nanotubes to ammonia vapor (10–50 ppm) was studied and compared with those of the films of pure MPc derivatives.
This paper deals with the combined approach to describing the evolution of weakly nonlinear three-dimensional moderately long perturbations of free surface of viscous liquid. The initial system of hydrodynamic equations is reduced to the novel model system of equations. The first of them is integro-differential equation for nonlinear perturbation of the free surface, taking into account non-stationary shear stress on a weakly sloping bottom. Another equation is an auxiliary linear equation for determining the liquid horizontal velocity vector, averaged over the layer depth. This vector is present in the main equation only in the term of the second order of smallness. The proposed model is suitable for finite-amplitude waves, traveling in different directions in the horizontal plane. Some problems of interactions and collisions of such perturbations over the horizontal and weakly sloping bottom are solved numerically.
Baculoviruses are a family of insect-specific pathogenic viruses can persist outside for long periods through the formation of occlusion bodies. In spite of this ability, the UV of sunlight is an essential factor that limits the survival of baculoviruses outside the host. In the current study, we compared the UV tolerance of two strains of Lymantria dispar multiple nucleopolyhedrovirus (LdMNPV), which were isolated in spatially different regions (LdMNPV-27/0 in Western Siberia (Russia) and LdMNPV-45/0 in North America (USA)) and dramatically differ in their potency. We exposed the studied strains to sunlight in an open area for 0.25, 0.5, 1, and 2 hours and later perorally inoculated host larvae with the same doses of virus (5x105) and with doses leading to same effect (LD90). We observed that strain LdMNPV-45/0, which previously showed high virulence against L. dispar larvae, was more sensitive to UV irradiation (estimated as the relative rate of inactivation (r, h -1) and as the half-life of the virus (τ1/2, h)) compared to LdMNPV-27/0. Exposure to sunlight induced a significant delay of LdMNPV-45/0-induced pathogenesis already after 0.25 h of sunlight exposure, while for LdMNPV-27/0 this delay was occurred only after 2 h exposure in spite of used concentrations. We also compared the sequences of the main structural proteins of the studied strains as UV light contributes not only to genome damage in viruses but also to structural protein damage. The most prominent genetic difference between the structural proteins of the strains was related to the loss of the virus enhancin factor-1 (vef-1) gene in the LdMNPV-27/0 strain. Thus initially highly potent viral strain (such as LdMNPV-45/0) is not recommend to use in the regions (or forest stand density) with high UV load. The role of virus enhancin factor-1 in baculovirus tolerance to UV needs for following studies.
Purpose. The article presents a historiographical review of the problems of research of ancient ceramics from archaeological sites of East Asia in the chronological interval from 20,000–18,000 to 9,000 years ago. Results. The subject of discussion is the periodization of monuments with early ceramics, the problems of socio-economic conditions of the emergence of pottery technology, its functional role in ancient societies, reconstruction of technological skills and technical levels of pottery, morphology and decor. There are a lot of controversial issues and “blind spots” in this direction. However, the opening of sites with ancient ceramics in East Asia showed that here, on the Pacific (eastern) outskirts of the Eurasian continent, pottery making technology first appeared about 10,000 years earlier than in the Middle East. The invention of ceramics in this region of the world at the turn of the Pleistocene and Holocene should be considered as a result of a combination of natural and social factors. The example of East Asia shows that the relationship between the appearance of ceramic vessels and the development of agriculture, as a technology for food production, is universally, not a mandatory factor. Conclusion. The article discusses certain regional differences in the formation of skills in making the most ancient ceramic vessels of East Asia. It is assumed that the development of ceramic technology in the Japanese archipelago and in the mainland areas of East Asia took place independently. For the Amur region, there are two local cultural traditions – Osipovskaya and Gromatukhinskaya. According to materials from Northern China, there is a version of the existence of a common line in the development of ancient ceramics in the Valley of the Nonny River. There are similarities between the early ceramics of Northeast China, and the Gromatukhinskaya and Osipovskaya cultures of Amur. For the ceramics of South Korea also note similarities with the materials of the Russian Far East, Japanese and Chinese dishes.