Hengzongshu/ArticleAgent huggingface dataset:
The first alkyl chain‐anchored heteropentacene, dithieno[2,3‐ d ;2′,3′‐ d ′]benzo‐[1,2‐ b ;3,4‐ b ′]dithiophene (DT m BDT), mono‐ or disubstituted with a nitronyl nitroxide group has been prepared through a cross‐coupling synthetic procedure of the corresponding dibromo‐derivative (Br 2 ‐DT m BDT) with a nitronyl nitroxide‐2‐ide gold(I) complex. The synthesized nitroxides possess high kinetic stability, which allowed us to investigate their structure and thermal, optical, electrochemical, and magnetic properties. Single‐crystal X‐ray diffraction of both mono‐ and diradicals revealed that the nitronyl nitroxide group lies almost in the same plane as the nearest side thiophene ring. Such arrangement favors formation of edge‐to‐edge dimers, which then form close π‐stacks surrounded by interdigitating alkyl chains. Before melting, these nitronyl nitroxide radical substituted molecules undergo at least two different phase transitions (PTs): for the monoradical, PTs are reversible, accompanied by hysteresis, and occur near 13 and 83 °C; the diradical upon heating shows a reversible PT with hysteresis in the temperature range 2–11 °C and an irreversible PT near 135 °C. PTs of this type are absent in Br 2 ‐DT m BDT. Therefore, the step‐by‐step substitution of bromine atoms by nitronyl nitroxide groups changes the structural organization of DT m BDT and induces the emergence of PTs. This knowledge may facilitate crystal engineering of π‐stacked paramagnets and related molecular spin devices.
Maturity onset diabetes of the young is a dominantly inherited form of monogenic diabetes, diagnosed mainly before the age of 35 years. Mutations in the HNF1A and HNF4A genes are associated with diabetes mellitus of the HNF1A-MODY and HNF4A-MODY subtypes, respectively. These two forms of MODY are characterized by dyslipidemia in addition to impaired glucose metabolism due to the altered function HNF1A and HNF4A proteins. The aim of this study was a genetic analysis of young patients with the MODY phenotype and dyslipidemia with a burdened family history. Material and methods . The probands underwent targeted DNA sequencing using the Illumina MiSeq NGS System. The target panel included the coding regions and splicing sites of MODY-associated genes: HNF4A, GCK, HNF1A, PDX1, HNF1B, NEUROD1, KLF11, CEL, PAX4, INS, BLK, KCNJ11, ABCC8, and APPL1. Results . A heterozygous single nucleotide deletion NM_000457.4: c.153del (3’rule) was found in proband P1 in the HNF4A gene. In proband P2, single nucleotide deletion NM_000545.8: c.335del (3 ‘rule) in the HNF1A gene was detected in a heterozygous state. Both variants are located in the coding parts of the genes, led to a shift in the reading frame and have not been described in the literature and databases earlier. Conclusions . Taking into account the phenotypic features of probands, we assume that the variants NM_000545.8: c.335del (rule 3) in the HNF1A gene and NM_000457.4: c.153del (rule 3) of the HNF4A gene are associated with different MODY subtypes in these individuals. After verification of MODY-HNF1A and MODY-HNF4A diagnosis, it is necessary to monitor the lipid profile parameters (total cholesterol, low and high density lipoprotein cholesterol, triglycerides) and prescribe appropriate drug therapy.
The level of polyteny of the Drosophila salivary gland chromosomes was determined throughout the chromosome region 89E1-4, the locus of the Bithorax Complex. A zone of underreplication spans the 300 kb of DNA from the Ubx to Abd-B loci. From the centromere proximal end of the complex, a 70-kb-long gradual decrease of polytenization starts with the Ubx transcription unit and, after a floor corresponding to the abd-A locus, raises gradually back to the maximum over 70 kb in the region of the Abd-B transcription unit.

In flies carrying the mutation Suppressor of DNA Underreplication [Su(UR)ES], the underreplication of the Bithorax Complex is fully suppressed. In the wild type, the Bithorax Complex forms a weak point featuring thinner bands separated by clefts or constrictions. In Su(UR)ES strain in contrast, the 89E1-4 band looks like a single solid band consisting of homogenous dense material.

We speculate that the wild-type Su(UR)ES protein hampers DNA replication of silenced domains and leads to their underreplication in salivary gland polytene chromosomes.
Currently, there is an active development of the Uzbek sector of the Internet. In it, as in other national sectors, the most common form of presentation of textual information is semi-structured documents, work that presupposes the availability of reliable algorithms for text analysis, including its lexical characteristics. The article offers an intelligent web application developed for morphological analysis of words in the Uzbek language. The web application is based on the concept of generation and stem analysis of the Uzbek language word forms. A well-known Porter algorithm was chosen as the basis for stemming. The morphoanalyzer generates word forms of the Uzbek language based on the division of words into certain classes, taking into account the specifics and structure of this language. For example, nouns can be classified by meaning (related, nominal), by quantity (singular and plural), by case, and also, by the endings of belonging (possessive).
The experimental research of heptadecane's crystallization front propagation is carried up on horizontal directed crystallization model. The temperature distributions on free surface are measured during crystallization front propagation process using thermal imager and thermocouples.

The time dependence of crystallization front form was investigated using digital video recording.
Elimaea fallax Bey-Bienko, Locusta migratoria Linnaeus and Trilophidia annulata (Thunberg) are recorded from Khabarovsky krai for the first time.

The new data show that some species mainly associated with the subtropical and tropical regions of Asia expand their ranges northward and north-eastward.

These shifts may be determined by both global warming and local transformations of habitats.
One of the most urgent issues faced by the oil and gas industry is how to increase the processing depth of associated petroleum gas (APG). In the Russian Federation alone, the annual economic losses from unutilised APG during processing are estimated at 2 billion dollars. It is known that the composition of APG can vary greatly, depending on the oil and gas field. In particular, the methane concentration, the main component of natural gas and associated gas, varies from 25 to 95 vol.%.

In this study, we sought to identify the main factors that determine the morphology and structure of CNF, and to develop approaches in processing actual hydrocarbon mixtures to produce a carbon product with the desired or predictable characteristics. Such an approach can serve as a basis for resource-saving catalytic technology utilizing C1–C4 hydrocarbons that are currently disposed of as post-combustion flare gas.

The research results clearly demonstrate that the morphology and texture of the carbon materials obtained by the decomposition of hydrocarbon mixtures depend on the composition of the reaction gas. The key components in this case are methane and the resultant hydrogen: their relationship at a specific temperature determines the direction of the reversible reaction of carbon hydrogenation: С + 2H2 = СH4. The decisive factor in the decomposition of hydrocarbons yielding carbon materials is the degree of deviation of the methanation reaction from equilibrium which can be influenced in two ways. The addition of hydrogen to the reaction gas promotes the driving force of the carbon hydrogenation reaction, resulting in defective high-surface carbon fibres. Increasing the concentration of methane in the reaction gas composition, in contrast, reduces the driving force of methanation until the process is suppressed, which promotes a more structured form of the CNF, without defects.
The results of testing new Agrostab computer program “Indicators of stability of agricultural crops varieties” based on long-term (2017–2019) field research data in Novosibirsk region are presented. The program implements modern methods for assessing the ecological plasticity of varieties and allows to evaluate the stability of genotypes by a set of phenotypic characters. The research material was common spring wheat varieties from the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (Novosibirskaya 15, Novosibirskaya 31, Sibirskaya 12), and collection forms of spring hexaploid triticale from the VIR world collection Lt-F6544-6 (k-3992), variety Ukro (k-3644) and Sears 57 × Ukro hybrid received as a result of breeding. The samples had a different ecological and geographical origin and belonged to different ripeness groups. Plants were grown organically without the use of fertilizers and pesticides. They were sown at different times after bare fallow in four repetitions. In the course of the experiment, the following genotype stability indicators were determined: environmental variance, coefficient of homeostaticity, weighted homeostacity index, steadiness of stability index, coefficient of multiplicativity, specific adaptive ability, superiority measure, ecovalence, regression to environmental index, non-parametric stability index. The necessity of using the complex value of the integrated selection index to calculate the parameters of plasticity and genotype stability is shown. Testing of the Agrostab program for breeding of spring triticale made it possible to determine the targeted vector for the selection of varieties in the agroclimatic conditions of Western Siberia and adaptive samples to be included in hybridization. The use of new models and methods of statistical data analysis to determine the environmental plasticity of varieties and hybrids will increase the efficiency of the breeding process.
Contrary to the recently demonstrated single longitudinal mode DFB Raman laser and short DBR Raman laser

In the present paper we experimentally demonstrate a generation in a short Raman fiber laser having 10 000 different longitudinal modes only. We design the laser using 12 meters of commercially available fiber. in the laser under study the number of modes is high enough for efficient nonlinear interactions

Experimentally measured time dynamics reveals the presence of mode correlations in the radiation: the measured extreme events lasts for more than 10 round-trips
The relationship of the pulsations of flow in the settling chamber with the pulsations of supersonic flow in the test section of the T-325 wind tunnel of ITAM SB RAS was investigated. Experimental data on the correlation between flow pulsations in different sections of wind tunnel and efficiency of turbulence reducing system were obtained. The system of three-channel hot-wire measurements in subsonic and supersonic flows was tested.
In our paper we present the results of seismotomographic inversion for the local seismological monitoring data obtained in the area of the Samoylov Island (Lena River delta) in 2019–2021. Tomographic velocity model was used for refining hypocenter locations of local earthquakes and for geological interpretation. The results are shown as maps of anomalies of seismic waves and Vp /Vs ratios for the 5 and 10 km depths. The velocity anomalies structure made it possible to interpret low Vp /Vs ratio as rocks related to the Siberian platform, and to compare between the boundary of the low Vp /Vs area and the trace of the known geological fault running along the Olenekskaya Channel.
The impact of uneven heating on a satellite structure in low Earth orbit has been considered using the example of 3U CubeSat. The calculations showed that the thermal deformation of CubeSat structure in orbit caused a deviation between normals to opposite small satellite sides of about 0.03°. Such a deviation is commensurate with the required satellite pointing accuracy approximately 0.1° necessary for satellite laser communication. It means that to solve similar problems in the CubeSat designing that require such or better CubeSat pointing accuracy, it is necessary to take into account the expected satellite structure thermal deformation.
The evolution of large amplitude internal waves propagating towards the shore and more specifically the run up phase over the "swash" zone is considered.

The mathematical model describing the generation, interaction, and decaying of solitary internal waves of the second mode in the interlayer is proposed. The exact solution specifying the shape of solitary waves symmetric with respect to the unperturbed interface is constructed.

It is shown that, taking into account the friction on interfaces in the mathematical model, it is possible to describe adequately the change in the phase and amplitude characteristics of two solitary waves moving towards each other before and after their interaction. It is demonstrated that propagation of large amplitude solitary internal waves of depression over a shelf could be simulated in laboratory experiments by internal symmetric solitary waves of the second mode.
Pulse wave velocity (PWV) has been recommended as an arterial damage assessment tool and a surrogate of arterial stiffness. However, the current technology does not allow to measure PWV both continuously and in real-time. We reported previously that peripherally measured ejection time (ET) overestimates ET measured centrally. This difference in ET is associated with the inherent vascular properties of the vessel.

In the current study we examined ETs derived from plethysmography simultaneously at different peripheral locations and examined the influence of the underlying arterial properties on ET prolongation by changing the subject's position. We calculated the ET difference between two peripheral locations (ΔET) and its corresponding PWV for the same heartbeat.

The ΔET increased with a corresponding decrease in PWV. The difference between ΔET in the supine and standing (which we call ET index) was higher in young subjects with low mean arterial pressure and low PWV. These results suggest that the difference in ET between two peripheral locations in the supine vs standing positions represents the underlying vascular properties. We propose ΔET in the supine position as a potential novel real-time continuous and non-invasive parameter of vascular properties, and the ET index as a potential non-invasive parameter of vascular reactivity.
By the numerical simulation of forced convection in microchannel with aspect ratio of 100:1 the experimental approach of calculating heat loss was verified. Experimental results on conjugate convective heat transfer are in good agreement with numerically obtained results for the distribution of the temperature and heat transfer coefficient for a laminar flow. Numerical and experimental results are discussed and explained for used test section. Proposed approach could be used to verify experimental data on heat transfer characteristics obtained in microchannels.
The Nuclear Pore Complex (NPC) regulates nucleocytoplasmic transport by providing small channels for passive diffusion and multiple docking surfaces that lead to a central translocation channel for active transport.

In this study we have investigated by high resolution scanning and transmission electron microscopy the dynamics of NPC structure in salivary gland nuclei from Chironomus during Balbiani ring (BR) mRNP translocation, and present evidence of rearrangement of the transporter related to mRNP export. Analysis of the individual NPC components verified a strong evolutionary conservation of NPC structure between vertebrates and invertebrates. The transporter is an integral part of the NPC and is composed of a central short double cylinder that is retained within the inner spoke ring, and two peripheral globular assemblies which are tethered to the cytoplasmic and nucleoplasmic coaxial rings by eight conserved internal ring filaments. Distinct stages of BR mRNP nuclear export through the individual NPC components were directly visualized and placed in a linear transport sequence. The BR mRNP first binds to the NPC basket, which forms an expanded distal basket ring. In this communication we present stages of BR mRNP transport through the nucleoplasmic, central and cytoplasmic transporter subunits, which change their conformation during mRNP translocation, and the emegence of mRNP into the cytoplasm.

We propose that the reorganization of the basket may be driven, in part, by an active translocation process at the transporter. Furthermore, the images provide dramatic evidence that the transporter functions as a central translocation channel with transiently open discrete gates in its globular assemblies. A model of NPC transporter reorganization accompanied with mRNP translocation is discussed.
Currently used recycling technologies have limitations on the composition of recyclable waste, which makes them specialized. Thus, the preliminary sorting of municipal solid waste is a necessary step, increasing the efficiency of using municipal solid waste as a resource.

To sort municipal solid waste we developed a method for detecting and classifying waste on a conveyor line using neural network image processing. Images from a camera are fed to a neural network input, which determines the position and type of detected objects. To train the neural network a database of more than 13,000 municipal solid waste images was created.

Mean-Average Precision for the neural network model was 64%.
In the current report, the effect of bioactive compounds of the M2 macrophage secretome on transcription of hippocampal genes in mice with a depression-like condition caused by social stress has been investigated.

Surgically resected hippocampus was used for mRNA isolation with following RNA sequencing procedures. Comparative analysis of transcriptomes from the control depressive mice treated with physiological saline solution and mice after intranasal administration of M2 macrophages-conditioned medium

revealed that remission of the depressive-like state is associated with a significant up- and downregulation of a number of genes, which were found to participate in restoration/regulation of ATP/Adenosine balance. Among the events associated with positive changes in behavioral pattern of depressive mice, the switch of microglial environment from a pro-inflammatory phenotype to an anti-inflammatory one, and subsequent restoration of compromised cannabinoid and glutamatergic transmitter pathways has been predicted.
Non-ionizing energy loss causes bulk damage to the silicon sensors of the ATLAS pixel and strip detectors. This damage has important implications for data-taking operations, charged-particle track reconstruction, detector simulations, and physics analysis. This paper presents simulations and measurements of the leakage current in the ATLAS pixel detector and semiconductor tracker as a function of location in the detector and time, using data collected in Run 1 (2010–2012) and Run 2 (2015–2018) of the Large Hadron Collider. The extracted fluence shows a much stronger | z |-dependence in the innermost layers than is seen in simulation. Furthermore, the overall fluence on the second innermost layer is significantly higher than in simulation, with better agreement in layers at higher radii. These measurements are important for validating the simulation models and can be used in part to justify safety factors for future detector designs and interventions.
The process e + e − → K + K − π 0 has been studied in the center-of-mass energy range from 1.2 to 2 GeV using a 80.6 pb −1 data sample collected with the CMD-3 detector at the electron-positron collider VEPP-2000.

Preliminary results of the cross-section measurement are presented.
High-loading Ni–Mo carbide catalysts were prepared by the modified gel-combustion method under various thermal treatment conditions. All samples were studied by X-ray diffraction (XRD) analysis, which showed that the catalysts could contain cubic and hexagonal molybdenum carbides, nickel, nickel oxide and Ni–Mo solid solutions, depending on the thermal treatment conditions. Study of catalyst activity and selectivity in the hydrogenation of furfural was carried out in a batch reactor at 150 °C and hydrogen pressure 6.0 MPa. Analysis of the reaction products showed that the highest yields of 2-methylfuran (2-MF) and furfuryl alcohol (FA) were achieved using catalysts synthesized by calcination of the nickel-molybdenum-carbon precursor at 400 °С with the following reduction in a stream of hydrogen at 600 °C. The best results for production of FA with a yield of 80 mol % and 2-MF with a yield of 29 mol % were observed using Ni6MoC–SiO2 (400/600) and Ni1MoC–SiO2 (400/600) catalysts, respectively. It has been shown that the addition of nickel to the carbide molybdenum catalyst significantly increases the activity of the catalytic systems. In addition, nickel also contributes to the formation of products formed by hydrogenation of the aromatic ring tetrahydrofurfuryl alcohol (THFA) and 2-methyltetrahydrofuran (2-MTHF).
Charm meson oscillations are observed in a time-dependent analysis of the ratio of ${D}^{0}\ensuremath{\rightarrow}{K}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ to ${D}^{0}\ensuremath{\rightarrow}{K}^{\ensuremath{-}}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\pi}}^{+}$ decay rates, using data corresponding to an integrated luminosity of $3.0\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ recorded by the LHCb experiment.

The measurements presented are sensitive to the phase-space averaged ratio of doubly Cabibbo-suppressed to Cabibbo-favored amplitudes ${r}_{D}^{K3\ensuremath{\pi}}$ and the product of the coherence factor ${R}_{D}^{K3\ensuremath{\pi}}$ and a charm mixing parameter ${y}_{K3\ensuremath{\pi}}^{\ensuremath{'}}$.

The constraints measured are ${r}_{D}^{K3\ensuremath{\pi}}=(5.67\ifmmode\pm\else\textpm\fi{}0.12)\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}2}$, which is the most precise determination to date, and ${R}_{D}^{K3\ensuremath{\pi}}{y}_{K3\ensuremath{\pi}}^{\ensuremath{'}}=(0.3\ifmmode\pm\else\textpm\fi{}1.8)\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}3}$, which provides useful input for determinations of the CP-violating phase $\ensuremath{\gamma}$ in ${B}^{\ifmmode\pm\else\textpm\fi{}}\ensuremath{\rightarrow}D{K}^{\ifmmode\pm\else\textpm\fi{}}$, $D\ensuremath{\rightarrow}{K}^{\ensuremath{\mp}}{\ensuremath{\pi}}^{\ifmmode\pm\else\textpm\fi{}}{\ensuremath{\pi}}^{\ensuremath{\mp}}{\ensuremath{\pi}}^{\ifmmode\pm\else\textpm\fi{}}$ decays. The analysis also gives the most precise measurement of the ${D}^{0}\ensuremath{\rightarrow}{K}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ branching fraction, and the first observation of ${D}^{0}$--${\overline{D}}^{0}$ oscillations in this decay mode, with a significance of 8.2 standard deviations.