Hengzongshu/ArticleAgent huggingface dataset:
Licensing of the western regions of the Republic of Sakha (Yakutia) was considered as of 03.01.2021. 76 subsoil plots were allocated on this territory and 23 companies engaged in geological exploration, exploration and production of hydrocarbons were registered.

The largest volume of exploration work was carried out by PJSC Surgutneftegas and Rosneft.

In the period from 2009 to 2020, 15 oil and gas fields were discovered.
The CMD-3 detector started data taking at the electron-positron collider VEPP-2000 in December 2010 with a goal to collect about 1 fb −1 . The collected data sample corresponds to an integrated luminosity of 200 pb −1 in the center-of-mass energy range from 0.32 up to 2 GeV. This paper reports recent results on the hadronic cross sections measurements with the CMD-3 detector.
Charge transport in amorphous oxide semiconductors is often described as the band transport affected by disorder in the form of random potential barriers (RB).Theoretical studies in the framework of this approach neglected so far the percolation nature of the phenomenon.In this article, a recipe for theoretical description of charge transport in the RB model is formulated using percolation arguments.Comparison with the results published so far evidences the superiority of the percolation approach.
In the review have been classified literature data concerning modern instrumental, microscopic and molecular (metabolomics, proteomics, genetics and epigenetics) approaches for early breast cancer diagnostics. The analytical performance and perspectives of their application in clinical practice also have been evaluated.
Three isostructural metal-organic frameworks ([Ln2(phen)2(NO3)2(chdc)2]·2DMF (Ln3+ = Y3+ for 1, Eu3+ for 2 or Tb3+ for 3; phen = 1,10-phenanthroline; H2chdc = trans-1,4-cyclohexanedicarboxylic acid) were synthesized and characterized. The compounds are based on a binuclear block {M2(phen)2(NO3)2(OOCR)4} assembled into a two-dime nsional square-grid network containing tetragonal channels with 26% total solvent-accessible volume. Yttrium (1)-, europium (2)- and terbium (3)-based structures emit in the blue, red and green regions, respectively, representing the basic colors of the standard RGB matrix. A doping of Eu3+ and/or Tb3+ centers into the Y3+-based phase led to mixed-metal compositions with tunable emission color and high quantum yields (QY) up to 84%. The bright luminescence of a suspension of microcrystalline 3 in DMF (QY = 78%) is effectively quenched by diluted cinnamaldehyde (cinnamal) solutions at millimolar concentrations, suggesting a convenient and analytically viable sensing method for this important chemical.
A new class of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors based on disaccharide nucleosides was identified. TDP1 plays an essential role in the resistance of cancer cells to currently used antitumour drugs based on Top1 inhibitors such as topotecan and irinotecan. The most effective inhibitors investigated in this study have IC50 values (half-maximal inhibitory concentration) in 0.4–18.5 µM range and demonstrate relatively low own cytotoxicity along with significant synergistic effect in combination with anti-cancer drug topotecan. Moreover, kinetic parameters of the enzymatic reaction and fluorescence anisotropy were measured using different types of DNA-biosensors to give a sufficient insight into the mechanism of inhibitor's action.
In the present work we have studied the dispersion of single-walled carbon nanotubes in liquid crystalline asymmetrically substituted phthalocyanines (MPc, where M [Formula: see text] Cu, Co, and 2H) bearing one pyrene and six polyoxy groups as side chains. The influence of single-walled carbon nanotubes on the phase behavior of MPcs was investigated using X-ray diffraction, polarized optical microscopy and differential scanning calorimetry. It was demonstrated that the incorporation of small amounts of single-walled carbon nanotubes ([Formula: see text]1 wt.%) does not alter the MPc mesophases. The structural features and the sensor response of composite thin films of MPc with single-walled carbon nanotubes to ammonia vapor (10–50 ppm) was studied and compared with those of the films of pure MPc derivatives.
Intensively evaporating liquid films shear-driven in a mini- or micro-channel under the action of cocurrent gas flow are promising for the use in modern cooling systems of semiconductor devices.

In this work, we investigated the influence of liquid and gas flow rates on the critical heat flux in a locally heated film of water, moving under the action of air flow in a mini-channel. In experiments a record value of critical heat flux of 870 W/cm2 was reached. Heat spreading into the substrate and heat losses to the atmosphere in total do not exceed 25 % at heat fluxes above 400 W/cm2.

A comparison with the critical heat flux for water flow boiling in the channel shows that, for shear-driven liquid films the critical heat flux is almost an order of magnitude higher.
Experimental modeling of the formation of graphite and diamond as a result of carbide–fluid interactions was performed in the Fe3C–SiO2–Al2O3–(Mg,Ca)CO3 systems at 6.3 and 7.5 GPa and 1100–1650 °C. In the experiments with ƒO2-gradient (7.5 GPa, 1250–1350 °C), graphite + magnesiowüstite + garnet ± cohenite assemblage was formed. Graphite was produced through the redox interactions of carbide with carbonate or CO2 (reducing conditions), and redox reactions of magnesiowüstite and CO2 (oxidizing conditions). At 1450–1650 °C, crystallization of graphite, garnet, magnesiowüstite and ferrospinel, as well as generation of Fe2+,3+-rich carbonate–silicate melt occurred. This melt, saturated with carbon, acted as a medium of graphite crystallization and diamond growth on seeds. In the experiments without ƒO2-gradient (6.3 GPa), decarbonation reactions with the formation of CO2-fluid and Fe,Mg,Ca-silicates, as well as C0-producing redox reactions of CO2-fluid with cohenite were simultaneously realized. As a result, graphite (± diamond growth) was formed in assemblage with Fe2+,Fe3+,Mg-silicates and magnetite (1100–1200 °C), or with Fe3+-rich garnet and orthopyroxene (1300–1500 °C). It has been established that a potential mechanism for the crystallization of graphite or diamond growth is the oxidation of cohenite by CO2-fluid to FeO and Fe3O4, accompanied by the extraction of carbon from Fe3C and the corresponding reduction of CO2 to C0.
We discovered a novel effect that can cause witness emittance growth in plasma wakefield accelerators. The effect appears in linear or moderately nonlinear plasma waves. The witness experiences a time-varying focusing force and loses quality during the time required for the drive beam to reach transverse equilibrium with the plasma wave. The higher the witness charge, the lower the emittance growth rate because of additional focusing of the witness by its own wakefield. However, the witness head always degrades, and the boundary between degraded and intact parts gradually propagates backward along the witness bunch.
To identify associations of fatty acids (FAs) with the antioxidant enzymes in the blood of men with coronary atherosclerosis and ischemic heart disease (IHD).

The study included 80 patients: control group-20 men without IHD, the core group-60 men with IHD. The core group was divided into subgroups: subgroup A-with the presence of vulnerable atherosclerotic plaques, subgroup B-with the absence of vulnerable atherosclerotic plaques. We analyzed the levels of FAs, free radicals, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in the blood.

Patients with IHD, compared with the control group: (1) had higher levels of SOD, CAT, myristic, palmitic, palmitoleic, and octadecenoic FAs; (2) had lower levels of GPx, α-linolenic, docosapentaenoic, docosahexaenoic, and arachidonic FAs. In subgroup A there were found: (1) negative associations of SOD-with linoleic, eicosatrienoic, arachidonic, eicosapentaenoic, docosapentaenoic and docosahexaenoic FAs, positive associations-with palmitic acid; (2) positive correlations of CAT level with palmitoleic and stearic acids; (3) negative associations between of GPx and palmitic, palmitoleic, stearic and octadecenoic FAs.Changes in the levels of antioxidant enzymes, and a disbalance of the FAs profile, probably indicate active oxidative processes in the body and may indicate the presence of atherosclerotic changes in the vessels.
Experimental data on the RNA content and RNA base composition in different microisolated cell compartments, and on the synthesis and processing of ribosomal RNA in cells of the Chironomus thummi salivary gland are presented. The nucleolus of a Chironomus salivary gland cell contains about 250 pg RNA representing nearly 50% of the RNA of chromosomal material. The RNA content of chromosomes I–III from 82, 79 and 73 pg corresponds well to their relative lengths. The base composition of nucleolar RNA (46.5% G + C) is similar to that of cytoplasmic RNA (47% G + C) but different from Balbiani ring RNA (37% G + C). The synthesis and processing of precursor and ribosomal RNA were studied in vitro by incubation of glands in Cannon's insect medium supplemented with [ 3 H]uridine and [ 3 H]cytidine, and in vivo by injection of the isotopes into animals followed by gel electrophoresis of RNA extracted from microisolated nuclear components (nucleolus, chromosomes, nuclear sap) and cytoplasm. During 1 h of incubation, mainly one RNA fraction with a molecular weight of about 3 × 10 6 (38‐S RNA) is synthesized within the nucleolus. This becomes converted into smaller RNA molecules of 1.66 ×10 6 (30‐S) and 0.96 × 10 6 (23‐S) during long‐term labelling (or under chase conditions). In some of the nucleolar RNA preparations 0.72 × 10 6 (18‐S) RNA was also detected. Low‐molecular‐weight RNA in the 4–5‐S range is present after all incubation times, but without a distinct 4‐S peak while 5‐S RNA increases in amount with time of incubation. An additional low‐molecular‐weight RNA possessing a molecular weight of about 0.77 × 10 5 was detected in preparations of nucleolar RNA labelled for at least 3 h. RNA from chromosomes I–III contains, besides HRNA and low‐molecular‐weight RNA, RNAs with molecular weights 1.55 × 10 6 (“30‐S”), 0.96 × 10 6 (23‐S) and/or 0.72 × 10 6 (18‐S) representing (pre)‐rRNA species. “30‐S” and 18‐S RNA are also present in the nuclear sap while a distinct 23‐S peak is absent. Although in whole larvae mature rRNAs can only be found after 1‐h labelling, clear rRNA peaks in cytoplasmic RNA from salivary glands are not found earlier than after a 6‐h incubation. An RNA of molecular weight 0.65 × 10 5 first observed in nucleolar RNA preparations and accumulated in cytoplasm is suggested to be (pre)‐rRNA formed during processing by an endonucleolytic activity.
Naturally coloured cotton is environmentally friendly, since bleaching and chemical dyeing are not needed during textile production. Studying molecular-genetic mechanisms underpinning pigment production may facilitate breeding cotton with coloured fibre. In the current review we summarize the known data on structural and regulatory genes involved in biosynthesis of flavonoid pigments proanthocyanidins (PAs) in brown and caffeic acid (CA) in green fibre. The first chapter considers the first studies on fibre cotton inheritance, from the beginning of the last century. Then, we briefly review the biochemical and physico-chemical methods proving the presence of PAs in brown fibre and derivatives of CA in green cotton fibre. The biochemical analysis of coloured cotton fibre was followed by genetic studies of structural genes coding for enzymes participating in PA and CA biosynthesis, transport and oxidation processes. We summarize the data on the genes coding for transcription factors from the MBW (MYB-bHLH-WD40) regulatory complex, which controls flavonoid biosynthesis in coloured cotton fibre. The regulatory gene most interesting as a target for markers-assisted breeding and genome editing is GhTT2-3A.
We report an observation of magnetooscillations of the microwave power transmitted through the high mobility two-dimensional electron system hosted by a GaAs quantum well. The oscillations reflect an enhanced absorption of radiation at high harmonics of the cyclotron resonance and follow simultaneously measured microwave-induced resistance oscillations (MIRO) in the dc transport.

The analysis of obtained results demonstrates that the low-B decay, magnitude, and polarization dependence of the transmittance oscillations accurately follow the theory describing photon-assisted scattering between distant disorder-broadened Landau levels. The extracted sample parameters reasonably well describe the concurrently measured MIRO.

Our results provide an insight into the MIRO polarization immunity problem and pave the way to probe diverse high-frequency transport properties of high-mobility systems using precise transmission measurements.
The paper presents a detail description of chromosome pairing and changes of nucleolar morphology during meiotic prophase in male house shrews.
Construction of the 4+ generation Siberian circular photon source (SKIF synchrotron) has started in Novosibirsk. It will initially be equipped with six research workstations. For two stations, synchrotron radiation is generated by superconducting wigglers, whose radiation power approaches 49 kW, and the power density on the axis is 92 kW/mrad 2 . Most of the optical devices of the stations operate in a vacuum.

The high energy density of the synchrotron beamline and the requirements for the values of thermal deformations lead to difficult conditions for the thermal management of optical elements. The article provides an overview of the applied and promising cooling systems; an example of a 3D calculation of a thermal diamond filter of workstation 1-5 is given.

the limit for the thermal load of the filter, at which the temperature of the diamond plate will not exceed 600 °C, is estimated.
The article presents the experience of converting non-targeted administrative data into research data, using as an example data on the income and property of deputies from local legislative bodies of the Russian Federation for 2019, collected as part of anticorruption operations. This particular empirical fragment was selected for the pilot study of administrative data, which includes assessing the possibility of integrating scattered fragments of information into a single database, assessing quality of data and their relevance for solving research problems, particularly analysis of high-income strata and the apparent trends towards individualization of private property. The system of indicators for assessing data quality includes their timeliness, availability, interpretability, reliability, comparability, coherence, errors of representation and measurement, and relevance. In the case of the data set in question, measurement errors are more common than representation errors. Overall the article emphasizes the notion that introducing new non-target data into circulation requires their preliminary testing, while data quality assessment becomes distributed both in time and between different subjects. The transition from created data to «obtained» data shifts the functions of evaluating its quality from the researcher-creator to the researcheruser. And though in this case data quality is in part ensured by the legal support for their production, the transformation of administrative data into research data involves assessing a variety of quality measurements — from availability to uniformity and accuracy.
Vegetation plays a key role in the global climate system via modification of the water and energy balance.

Response of different vegetation types to present and projected climatic conditions was assessed for Siberia. The study was performed using JSBACH land surface model with atmospheric conditions obtained from INMCM4 modelling results. A climate change was determined according to the RCP 8.5 scenario.

A geographical redistribution of extratropical forest and grass vegetation and weakening of a canopy ability to absorb carbon dioxide from the atmosphere were obtained for climate warming conditions for Siberia. It was established that Eastern Siberia is more sensitive to climate forcing than Western Siberia.
We propose an experiment to search for a new gauge boson A' in e+e− annihilation by means of a positron beam incident on a gas hydrogen target internal to the bypass at the VEPP-3 storage ring.

The search method is based on a missing mass spectrum in the reaction e+e−→ γA'. It allows observation of the A' signal independently of its decay modes and life time.

The projected result of this experiment corresponds to an upper limit on the square of the coupling constant ε2=3⋅ 10−8 with a signal-to-noise ratio of two to one at an A' mass of 5–20 MeV.
According to the results of a comprehensive sedimentological study of the core and well log data, the dissection of the bat-upper Jurassic sediments of the South of the West Siberian oil and gas basin was carried out. Quasi-isochronous marked levels are identified. They are represented by transgressive surfaces, maximum flooding surfaces and extended carbonaceous layers. They are the basis of the performed correlation. A number of characteristic lithological-facies sequences diagnosed by well log data was established.
A new model of TU game is introduced and studied. Here apart from the characteristic function, two additional functions are used: relations between the players and the probability of coalition formation. We suggest and study the sufficient properties of the probability function to transform it into a probability measure. The generalized Shapley's value is defined for a new class of games by analogy with the original Shapley approach. For the games under study, we give the axiomatization of value functions. It unambiguously characterizes the (generalized) Shapley's value.
Small hairpin RNAs (shRNAs) became an important research tool in cell biology. Reliable design of these molecules is essential for the needs of large functional genomics projects. To optimize the design of efficient shRNAs, we performed comparative, thermodynamic, and correlation analyses of ~18,000 miR30-based shRNAs with known functional efficiencies, derived from the Sensor Assay project (Fellmann et al., 2011). We identified features of the shRNA guide strand that significantly correlate with the silencing efficiency and performed multiple regression analysis, using 4/5 of the data for training purposes and 1/5 for cross validation. A model that included the position-dependent nucleotide preferences was predictive in the cross-validation data subset (R = 0.39). However, a model, which in addition to the nucleotide preferences included thermodynamic shRNA features such as a thermodynamic duplex stability and position-dependent thermodynamic profile (dinucleotide free energy) was performing better (R = 0.53). Software "miR_Scan" was developed based upon the optimized models. Calculated mRNA target secondary structure stability showed correlation with shRNA silencing efficiency but failed to improve the model. Correlation analysis demonstrates that our algorithm for identification of efficient miR30-based shRNA molecules performs better than approaches that were developed for design of chemically synthesized siRNAs (R(max) = 0.36).
Type 2 diabetes (T2D) is a metabolic disorder characterized by disturbances of carbohydrate, fat and protein metabolism and insulin resistance. The majority of T2D patients are obese and obesity by itself may be a cause of insulin resistance. Our aim was to evaluate whether the recently identified T2D risk alleles are associated with human measures of fatness as characterized with Dual Energy X-ray Absorptiometry (DEXA).Genotypes and phenotypes of approximately 3,000 participants from cross-sectional ERF study were analyzed. Nine single nucleotide polymorphisms (SNPs) in CDKN2AB, CDKAL1, FTO, HHEX, IGF2BP2, KCNJ11, PPARG, SLC30A8 and TCF7L2 were genotyped. We used linear regression to study association between individual SNPs and the combined allelic risk score with body mass index (BMI), fat mass index (FMI), fat percentage (FAT), waist circumference (WC) and waist to hip ratio (WHR). Significant association was observed between rs8050136 (FTO) and BMI (p = 0.003), FMI (p = 0.007) and WC (p = 0.03); fat percentage was borderline significant (p = 0.053). No other SNPs alone or combined in a risk score demonstrated significant association to the measures of fatness.From the recently identified T2D risk variants only the risk variant of the FTO gene (rs8050136) showed statistically significant association with BMI, FMI, and WC.
A popular version of the finite strain Maxwell fluid is considered, which is based on the multiplicative decomposition of the deformation gradient tensor. The model combines Newtonian viscosity with hyperelasticity of Mooney-Rivlin type; it is a special case of the viscoplasticty model proposed by Simo and Miehe (1992).

A simple, efficient and robust implicit time stepping procedure is suggested. Lagrangian and Eulerian versions of the algorithm are available, with equivalent properties. The numerical scheme is iteration free, unconditionally stable and first order accurate. It exactly preserves the inelastic incompressibility, symmetry, positive definiteness of the internal variables, and w-invariance. The accuracy of the stress computations is tested using a series of numerical simulations involving a non-proportional loading and large strain increments.

In terms of accuracy, the proposed algorithm is equivalent to the modified Euler backward method with exact inelastic incompressibility; the proposed method is also equivalent to the classical integration method based on exponential mapping. Since the new method is iteration free, it is more robust and computationally efficient. The algorithm is implemented into MSC.MARC and a series of initial boundary value problems is solved in order to demonstrate the usability of the numerical procedures.
Interregional integration is the most important property and form of manifestation of the unity of any economic space, in particular Russian. The study of this phenomenon is a significant area of research on the spatial development of the country. In the article the historical preconditions of the used approaches based on the theory of economic equilibrium have been studied and systematized. We have described and analyzed various forms of spatial economic equilibrium which are adequate to the modern level of development and mathematical representation of economy. The development of the concept of economic equilibrium in economic and mathematical models is presented. It is shown that the simplicity of the mathematical structure of the OMIOM allows, using all the concepts of economic equilibrium, to analyze the features of interregional economic interactions and assess the degree of economic interdependence of the regions of Russia. The economic space in the OMIOM is presented discretely, in the context of macro-regions, which are federal districts or their large fragments, uniting several subjects of the federation. The economy of each macroregion is presented in the context of the aggregated sectors of production of goods and services. For sectors with transportable products, interregional transport and economic ties are taken into account.