Hengzongshu/ArticleAgent huggingface dataset:
The results of testing new Agrostab computer program "Indicators of stability of agricultural crops varieties" based on long-term (2017–2019) field research data in Novosibirsk region are presented. The program implements modern methods for assessing the ecological plasticity of varieties and allows to evaluate the stability of genotypes by a set of phenotypic characters.

The research material was common spring wheat varieties from the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (Novosibirskaya 15, Novosibirskaya 31, Sibirskaya 12), and collection forms of spring hexaploid triticale from the VIR world collection Lt-F6544-6 (k-3992), variety Ukro (k-3644) and Sears 57 × Ukro hybrid received as a result of breeding. The samples had a different ecological and geographical origin and belonged to different ripeness groups. Plants were grown organically without the use of fertilizers and pesticides. They were sown at different times after bare fallow in four repetitions. In the course of the experiment, the following genotype stability indicators were determined: environmental variance, coefficient of homeostaticity, weighted homeostacity index, steadiness of stability index, coefficient of multiplicativity, specific adaptive ability, superiority measure, ecovalence, regression to environmental index, non-parametric stability index.

The necessity of using the complex value of the integrated selection index to calculate the parameters of plasticity and genotype stability is shown. Testing of the Agrostab program for breeding of spring triticale made it possible to determine the targeted vector for the selection of varieties in the agroclimatic conditions of Western Siberia and adaptive samples to be included in hybridization. The use of new models and methods of statistical data analysis to determine the environmental plasticity of varieties and hybrids will increase the efficiency of the breeding process.
The mucus layer in the intestine plays a critical role in regulation of host-microbe interactions and maintaining homeostasis. Disruptions of the mucus layer due to genetic, environmental, or immune factors may lead to inflammatory bowel diseases (IBD). IBD frequently are accompanied with infections, and therefore are treated with antibiotics. Hence, it is important to evaluate risks of antibiotic treatment in individuals with vulnerable gut barrier and chronic inflammation. Mice with a knockout of the Muc2 gene, encoding the main glycoprotein component of the mucus, demonstrate a close contact of the microbes with the gut epithelium which leads to chronic inflammation resembling IBD.

Here we demonstrate that the Muc2-/- mice harboring a gut protozoan infection Tritrichomonas sp. are susceptible to an antibiotic-induced depletion of the bacterial microbiota. Suppression of the protozoan infection with efficient metronidazole dosage or L-fucose administration resulted in amelioration of an illness observed in antibiotic-treated Muc2-/- mice.

Fucose is a monosaccharide presented abundantly in gut glycoproteins, including Mucin2, and is known to be involved in host-microbe interactions, in particular in microbe adhesion. We suppose that further investigation of the role of fucose in protozoan adhesion to host cells may be of great value.
In this work we have described the translatome of two mammalian cell lines, NIH3T3 and Jurkat, by scoring the relative polysome association of ∼10,000 mRNA under normal and ER stress conditions.

We have found that translation efficiencies of mRNA correlated poorly with transcript abundance, although a general tendency was observed so that the highest translation efficiencies were found in abundant mRNA. Despite the differences found between mouse (NIH3T3) and human (Jurkat) cells, both cell types share a common translatome composed by ∼800–900 mRNA that encode proteins involved in basic cellular functions. Upon stress, an extensive remodeling in translatomes was observed so that translation of ∼50% of mRNA was inhibited in both cell types, this effect being more dramatic for those mRNA that accounted for most of the cell translation. Interestingly, we found two subsets comprising 1000–1500 mRNA whose translation resisted or was induced by stress. Translation arrest resistant class includes many mRNA encoding aminoacyl tRNA synthetases, ATPases and enzymes involved in DNA replication and stress response such as BiP. This class of mRNA is characterized by high translation rates in both control and stress conditions. Translation inducible class includes mRNA whose translation was relieved after stress, showing a high enrichment in early response transcription factors of bZIP and zinc finger C2H2 classes. Unlike yeast, a general coordination between changes in translation and transcription upon stress (potentiation) was not observed in mammalian cells. Among the different features of mRNA analyzed, we found a relevant association of translation efficiency with the presence of upstream ATG in the 5′UTR and with the length of coding sequence of mRNA, and a looser association with other parameters such as the length and the G+C content of 5′UTR.

A model for translatome remodeling during the acute phase of stress response in mammalian cells is proposed.
Terahertz (THz) radiation is very promising for chemical and biological sensing. One of the ways to realize a THz sensor is exciting multipole localized surface plasmon resonances (LSPRs) on subwavelength corrugated metal disks. In this paper, numerical modeling and analysis of LSPRs on a periodic array of such structures were made. At normal incidence of the incoming wave, only dipole resonances can be excited. An additional C-shaped resonator placed in the vicinity of the disk produces dark multipole modes (quadrupole, hexapole, octupole, and decapole ones) due to hybridization of these modes with the brigth dipole mode of the C resonator. Besides, multipole modes can be excited at oblique illumination of the structure. With increase in the incident angle, the multipole resonances become stronger. The high Q-factor resonance modes observed for PEC disks are wider or disappeared in case of Drude gold permittivity.
HPHT diamond synthesis using catalysts based on magnesium demonstrates a number of intriguing characteristics. In this highlight, we review the major characteristics of the growth, morphology, internal structure, and defect and impurity content of diamonds crystallized using Mg-based catalysts.
We study charmless B+ meson decays to the pΛ¯π+π− final state using a 605 fb−1 data sample collected at the Υ(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e− collider. There are significant signals found with the pΛ¯ mass peaking near threshold. The observed branching fraction for nonresonant B+→pΛ¯π+π− is (5.92−0.84+0.88(stat)±0.69(syst))×10−6 with a significance of 9.1 standard deviations. We also observe the intermediate three-body decay B+→pΛ¯ρ0 with a branching fraction of (4.78−0.64+0.67(stat)±0.60(syst))×10−6 and a significance of 9.5 standard deviations, and find a hint of a B+→pΛ¯f2(1270) signal. No other intermediate three-body decay is found in this study.Received 30 October 2009DOI:https://doi.org/10.1103/PhysRevD.80.111103©2009 American Physical Society
A method is implemented to perform "fast" adiabatic variation of the spin Hamiltonian by imposing the constant adiabaticity condition.

The method is applied to improve the performance of singlet-state Nuclear Magnetic Resonance (NMR) experiments, specifically, for efficient generation and readout of the singlet spin order in coupled spin pairs by applying adiabatically ramped RF-fields. Test experiments have been performed on a specially designed molecule having two strongly coupled 13C spins and on selectively isotopically labelled glycerol having two pairs of coupled protons. Optimized RF-ramps show improved performance in comparison, for example, to linear ramps.

We expect that the methods described here are useful not only for singlet-state NMR experiments but also for other experiments in magnetic resonance, which utilize adiabatic variation of the spin Hamiltonian.
Previous studies have documented 10 species from the genus Liostrea (L.delta, L. cucurbita, L. praeanabarensis, L. anabarensis, L. plastica, L. gibberosa, L

The present study reviews the taxonomy of Late Jurassic-Early Cretaceous oysters from the Northern and the Subpolar Urals (Western Siberia) and northern East Siberia
The deflection of charged particles is an intuitive way to visualize an electromagnetic oscillation of coherent light.

Here, we present a real-time ultrafast oscilloscope for time-frozen visualization of a terahertz (THz) optical wave by probing light-driven motion of relativistic electrons. We found the unique condition of subwavelength metal slit waveguide for preserving the distortion-free optical waveform during its propagation. Momentary stamping of the wave, transversely travelling inside a metal slit, on an ultrashort wide electron bunch enables the single-shot recording of an ultrafast optical waveform. As a proof-of-concept experiment, we successfully demonstrated to capture the entire field oscillation of a THz pulse with a sampling rate of 75.7 TS/s.

Owing to the use of transversely-wide and longitudinally-short electron bunch and transversely travelling wave, the proposed 'single-shot oscilloscope' will open up new avenue for developing the real-time petahertz (PHz) metrology.
The aim of study was to detect H5N1 virus in wild geese in Qinghai Province in 2012. The work was provided according to WHO and OIE guidelines. In 2012, we collected 532 samples from wild geese of two species: Bar-headed Goose (Anser indicus) and Graylag Goose (Anser anser). We analyzed samples by chicken embryo inoculation and PCR. No avian influenza viruses were isolated. History of HPAI H5N1 shows obvious importance of Central Asian region in its spreading. The outbreaks of the H5N1 Highly Pathogenic Avian Influenza (HPAI H5N1) were reported in wild birds at the Qinghai Lake since 2005. This area seems to be key point for H5N1 avian influenza surveillance in wild birds. We did not find viruses although H5N1 cases in poultry were reported from 5 provinces of China in 2012. Annual surveillance is required for early AIV detection in this region.
Physically meaningful simulations in plasma physics and astrophysics need powerful hybrid supercomputers equipped with computation accelerators. The development of parallel numerical codes for such supercomputers is a complex scientific problem. In order to solve it the concept of co-design is employed. The co-design is defined as considering the architecture of the supercomputer at all stages of the development of the code. The use of co-design is shown by the example of two physical problems: the interaction of an electron beam with plasma and the collision of galaxies. The resulting speedup and efficiency are shown.
The study reviews approaches to macro-economic and macro-territorial modelling presented in international and Russian economic publications. We focus on opportunities to improve forecasting the development of economic system in Russia at the macro-economic, inter-sectoral and inter-regional levels. We described dynamic macro-economic, inter-sectoral and inter- regional models developed in the Institute of Economics and Industrial Engineering of the Siberian Branch of the Russian Academy of Sciences (IEIE SB RAS). We analyse more in details three complex models proposed in IEIE SB RAS: CAISI (comprehensive analysis of inter-sectoral information), SRNES (synthesis of regional and national economic systems) and CSNES (coordination of sectoral and national economic solutions). We consider theoretical foundations of the complex models and their application in analysing and forecasting economic system development at various levels. The three complex models are based on different basic models that influence their development. IEIE SB RAS has been developing a two-level system of forecasting models, which combines advantages of dynamic stochastic general equilibrium models and dynamic input-output models applied in the CAISI system. The paper describes theoretical foundations of the SRNES system, whose latest versions are premised on the general equilibrium and cooperative games theories. Then, we characterised the most developed elements of the complex model CSNES, which has the CSNES-TEK subsystem used in forecasting developments in the fuel and energy industry of Russia’s territories and SIBARP (balance calculation system for the future). The conclusion outlines directions for further research on improving the methods of macro-economic, inter-regional, and inter-sectoral forecasting based on harmonisation of analytical and forecast calculations performed using the CAISI, SRNES and CSNES systems. The results of forecast calculations using the two-level system of macro-level models can be applied in the complex models SRNES and CSNES to ensure coordination between the forecasts of socio-economic development of the Asian part of Russia and projected dynamics of macro-indicators.
We applied canonical transformation to water wave equation not only to remove cubic nonlinear terms but to simplify drastically fourth order terms in Hamiltonian. This transformation explicitly uses the fact of vanishing exact four waves interaction for water gravity waves for 2D potential fluid. After the transformation well-known but cumbersome Zakharov equation is drastically simplified and can be written in X-space in compact way. This new equation is very suitable as for analytic study as for numerical simulation. Localized in space breather-type solution was found. Numerical simulation of collision of two such breathers strongly supports hypothesis of integrability of 2-D free surface hydrodynamics.
BACKGROUND: Guidelines on the required number of ambulatory blood pressure (ABP) readings focus on individual patients. Clinical researchers often face the dilemma of applying recommendations and discarding potentially valuable information or accepting fewer readings.

METHODS: Starting from ABP recordings with ≥30/≥10 awake/asleep readings in 4277 participants enrolled in eight population studies in the International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes (IDACO), we randomly selected a certain number of readings (from 30 to 1 awake and 10 to 1 asleep readings) at a time over 1000 bootstraps at each step. We evaluated: (i) concordance of the ABP level; (ii) consistency of the cross-classification based on office blood pressure and ABP; and (iii) accuracy in predicting cardiovascular complications. For each criterion, we fitted a regression line joining data points relating outcome to the number of readings covering the ranges of 30-20/10-7 for awake/asleep readings.

RESULTS: Reducing readings widened the SD of the systolic/diastolic differences between full (reference) and selected recordings from 1.7/1.2 (30 readings) to 14.3/10.3 mm Hg (single reading) during wakefulness, and from 1.9/1.4 to 10.3/7.7 mm Hg during sleep; lowered the κ statistic from 0.94 to 0.63, and decreased the hazard ratio associated with 10/5 mm Hg increments in systolic/diastolic ABP from 1.21/1.14 to 1.06/1.04 during wakefulness and from 1.26/1.17 to 1.14/1.08 during sleep. The first data points falling off these regression lines during wakefulness/sleep corresponded to 8/3 and 8/4 readings for criteria (i) and (iii) and to 5 awake readings for criterion (ii). CONCLUSIONS: 24-h ambulatory recordings with ≥8/≥4 awake/asleep readings yielded ABP levels similar to recordings including the guideline-recommended ≥20/≥7 readings. These criteria save valuable data in a research setting, but are not applicable to clinical practice.
The use of the endoscopic technique largely improves treatment outcomes in patients with multilocular hydrocephalus. However, impaired anatomy and the lack of usual landmarks often cause problems in planning and intraoperative identification of changed structures.

The use of frameless navigation during endoscopic interventions can significantly facilitate surgeon tasks and increases the efficacy of surgery. During surgery, the neuronavigation system visualizes a rigid endoscope that interconnects separated ventricles and cysts. Surgery can be completed with guiding a stent through an operating channel of the endoscope and implanting a shunt system.Ten children underwent 11 endoscopic interventions using frameless intraoperative navigation at our clinic in 2013-2014. The number of surgically interconnected compartments ranged from 3 to 5. Simultaneous placement of a shunt system was performed in 8 of 11 interventions.

Clinical improvement as a result of the operation was achieved in all children. 2 patients underwent re-operations 5 months and 1 year after endoscopic intervention.Thus, the use of frameless navigation during endoscopic interventions makes their implementation most efficient and safe for the patient.
Expression of the CNDP2 gene is frequently up- or down-regulated in different types of human cancers. However, how the product of this gene is involved in cell growth and proliferation is poorly understood. Moreover, our knowledge of the functions of the CNDP2 orthologs in well-established model organisms is scarce. In particular, the function of the D. melanogaster ortholog of CNDP2, encoded by the CG17337 gene (hereafter referred to as dCNDP2), is still unknown. This study was aimed at developing a set of genetic and molecular tools to study the roles of dCNDP2. We generated a dCNDP2 null mutation (hereafter ∆dCNDP2) using CRISPR/Cas9-mediated homologous recombination (HR) and found that the ∆dCNDP2 mutants are homozygous viable, morphologically normal and fertile. We also generated transgenic fly lines expressing eGFP-tagged and non-tagged dCNDP2 protein, all under the control of the UAS promoter, as well as polyclonal antibodies specific to dCNDP2. Using these tools, we demonstrate that only one of the two predicted dCNDP2 isoforms is expressed throughout the different tissues tested. dCNDP2 was detected in both the cytoplasm and the nucleus, and was found to be associated with multiple sites in the salivary gland polytene chromosomes. The dCNDP2 gene is not essential for fly viability under standard laboratory conditions. The subcellular localization pattern of dCNDP2 suggests that this protein might have roles in both the cytoplasm and the nucleus. The genetic and molecular tools developed in this study will allow further functional characterization of the conserved CNDP2 protein using D. melanogaster as a model system.
The characteristics of explosive boiling of water, propanol-1, propanol-2, n-nonane were obtained using optical method for measuring the laser intensity reflected from the microheater surface. A multi-layered thin film heater was used in the experiments with size of 100x110 μm. The experimental data show that high heat flux density provides the conditions for the phase explosion patterns. Four major stages of explosive boiling on microheater were selected and the dynamics of filling the heater surface with vapor phase, the lifetime of the main vapor bubble and the satellite bubble were determined.
We define a scale of mappings that depends on two real parameters p and q, and a weight function θ. In the case of q = p = n, θ ≡ 1, we obtain the well known mappingswith bounded distortion. Mappings of a two-index scale inherit many properties of mappings with bounded distortion. They are used for solving a few problems of global analysis and applied problems.
Massive open online courses (MOOCs) have attracted a great deal of interest in recent years as a new learning technology. Since MOOCs inception, only limited research has been carried out to address how learners perceive success in MOOCs after course completion. The aim of this study was to investigate the perceived benefits as the measurement of learning success. Narrative interviews were conducted with 30 Russian-speaking learners who completed at least one MOOC in full. By employing text analysis of interview transcripts, we revealed the authentic voices of participants and gained deeper understanding of learners' perceived benefits based on retrospective reflection. The findings of the study indicate that after finishing MOOCs, learners have received tangible and intangible benefits that in general justified their expectations. University-affiliated students, as well as working professionals, recognized the complementarity of MOOCs, but their assessments were limited to educational tracks. We discovered that taking MOOCs often coincided with the time when an individual was planning to change career, education, or life tracks. The results of the study and their implications are further discussed, together with practical suggestions for MOOC providers.
The IWGSC strategy for construction of the reference sequence of the bread wheat genome is based on first obtaining physical maps of the individual chromosomes. Our aim is to develop and use the physical map for analysis of the organization of the short arm of wheat chromosome 5B (5BS) which bears a number of agronomically important genes, including genes conferring resistance to fungal diseases. A physical map of the 5BS arm (290 Mbp) was constructed using restriction fingerprinting and LTC software for contig assembly of 43,776 BAC clones. The resulting physical map covered ~ 99% of the 5BS chromosome arm (111 scaffolds, N50 = 3.078 Mb). SSR, ISBP and zipper markers were employed for anchoring the BAC clones, and from these 722 novel markers were developed based on previously obtained data from partial sequencing of 5BS. The markers were mapped using a set of Chinese Spring (CS) deletion lines, and F2 and RICL populations from a cross of CS and CS-5B dicoccoides. Three approaches have been used for anchoring BAC contigs on the 5BS chromosome, including clone-by-clone screening of BACs, GenomeZipper analysis, and comparison of BAC-fingerprints with in silico fingerprinting of 5B pseudomolecules of T. dicoccoides. These approaches allowed us to reach a high level of BAC contig anchoring: 96% of 5BS BAC contigs were located on 5BS. An interesting pattern was revealed in the distribution of contigs along the chromosome. Short contigs (200–999 kb) containing markers for the regions interrupted by tandem repeats, were mainly localized to the 5BS subtelomeric block; whereas the distribution of larger 1000–3500 kb contigs along the chromosome better correlated with the distribution of the regions syntenic to rice, Brachypodium, and sorghum, as detected by the Zipper approach. The high fingerprinting quality, LTC software and large number of BAC clones selected by the informative markers in screening of the 43,776 clones allowed us to significantly increase the BAC scaffold length when compared with the published physical maps for other wheat chromosomes. The genetic and bioinformatics resources developed in this study provide new possibilities for exploring chromosome organization and for breeding applications.
This problem has a wide range of technical applications, ranging from the modeling of emergency operation of the liquid-metal nuclear reactors to the depressurization of underwater pipelines, functioning of the shipboard technical systems, etc.

The paper deals with the problem of numerical simulation of the modes of pulse air outflow into a vertical pipe, filled with liquids with different physical properties (water, ethanol, glycerol), implemented in the OpenFOAM software package. For obtaining verification data visualization experiments were carried out.

The results of numerical simulation and experimental data are in satisfactory agreement.