Hengzongshu/ArticleAgent huggingface dataset:
To assess age and sex characteristics of hostility among the population of a medium urban Siberian city.

Cross-sectional epidemiological studies were carried out among men and women aged 25-64 years in Tyumen; the response rate was 85,0% among men and 70,3% among women. To assess hostility, the algorithms of the WHO program MONICA-Psychosocial were used. There were low, moderate and high levels of hostility. Low hostility was considered the population norm.

In the open population of a medium urban Siberian city, an unfavorable data was found for the hostility prevalence. High levels of hostility were revealed in both men and women in the whole age range. However, a high level of hostility prevailed among women compared to general population values by age and in four decades of life. The data obtained will help to develop evidence-based prevention programs based on the effects on psychosocial factors taking into account age and sex characteristics.
To examine whether the widely used Strengths and Difficulties Questionnaire (SDQ) can validly be used to compare the prevalence of child mental health problems cross nationally.

We used data on 29,225 5- to 16-year olds in eight population-based studies from seven countries: Bangladesh, Brazil, Britain, India, Norway, Russia and Yemen. Parents completed the SDQ in all eight studies, teachers in seven studies and youth in five studies. We used these SDQ data to calculate three different sorts of 'caseness indicators' based on (1) SDQ symptoms, (2) SDQ symptoms plus impact and (3) an overall respondent judgement of 'definite' or 'severe' difficulties. Respondents also completed structured diagnostic interviews including extensive open-ended questions (the Development and Well-Being Assessment, DAWBA). Diagnostic ratings were all carried out or supervised by the DAWBA's creator, working in conjunction with experienced local professionals.

As judged by the DAWBA, the prevalence of any mental disorder ranged from 2.2% in India to 17.1% in Russia. The nine SDQ caseness indicators (three indicators times three informants) explained 8-56% of the cross-national variation in disorder prevalence. This was insufficient to make meaningful prevalence estimates since populations with a similar measured prevalence of disorder on the DAWBA showed large variations across the various SDQ caseness indicators. The relationship between SDQ caseness indicators and disorder rates varies substantially between populations: cross-national differences in SDQ indicators do not necessarily reflect comparable differences in disorder rates. More generally, considerable caution is required when interpreting cross-cultural comparisons of mental health, particularly when these rely on brief questionnaires.
The TRPM8 gene encodes the ion channel, which is a cold receptor in afferent neurons of the mammalian somatosensory system. We studied the frequency of haplotype distribution from six SNPs in the TRPM8 gene in Eurasian human populations, including Russians, Kazakhs and Chukchi. Four of the six SNPs are located in exon 7 (rs13004520, rs28901637, rs11562975, rs17868387), rs7593557 is in exon 11. These exons encode parts of the N-terminus, which is necessary for channel functioning in the plasma membrane of neurons. The rs11563071 is in exon 23 encoding part of the C-terminus. The primary difference in population distribution of haplotypes determines the SNP from exon 11 which leads to Ser419Asn substitution in protein. The most pronounced dif­ferences in the patterns of diversity and frequencies of haplotypes were observed between Chukchi and Russians. The frequency of major H1 haplotype encompassing the 419Ser gene variant differs in examined populations; 0.738 (Russians), 0.507 (Kazakhs) and 0.337 (Chukchi), p < 0.001. The TRPM8 gene variants encoding 419Asn and carrying the minor alleles of rs28901637 (P249P) and rs11562975 (L250L) in exon 7 are characteristic of Asian populations. The frequency of all 419Asn variants in Chukchi is comparable to that in Africans, however, the minor allele frequencies of rs28901637, rs11562975 in Africans is low. Apparently in the process of human colonization of Eurasia, minor alleles of these SNPs diverged depending on rs7593557 structure in exon 11. We analyzed sequences of five TRPM8 mRNA isoforms extracted by researchers from different tissues. Sequence analysis demonstrates that they are transcribed from major H1 variant of the TRPM8 gene but contain different translation start codons, which are generated by alternative splicing from pro-mRNA.
We show the main directions of work of the West Siberian archaeological detachment (team) of the Institute of Archaeology and Ethnography SB RAS, demonstrate the methods used and present the results and the possibilities of their interpretation. In 2018, the West Siberian archaeological detachment celebrates the 45th anniversary of its formation. The long-term head of the team is academician V. I. Molodin.

All studies are carried out within the framework of a multidisciplinary approach starting from the search for archaeological objects (sites Tartas-1, Vengerovo-2, -2A, -6, Staryi Tartas-5, Ust’-Tartas-1,-2; Chicha-1, Vengerovo-6 and others) to their laboratory investigation. We widely apply a range of analytical methods in all of our activities including almost all stages of research: from the search for archaeological sites to their processing in close cooperation with various scientists. We collaborate with specialists from the Institute of Geology and Mineralogy SB RAS, Novosibirsk, Russia; the Institute of Petroleum Geology and Geophysics SB RAS, Novosibirsk, Russia; the Institute of Solid State Chemistry and Mechanochemistry SB RAS, Novosibirsk, Russia; the Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia; the Institute of Nuclear Physics SB RAS, Novosibirsk, Russia; Novosibirsk National Research State University, Novosibirsk, Russia; the Center of Collective Use (CCU) “Geochronology of Cenozoic”, Novosibirsk, Russia; Heidelberg University, Heidelberg, Germany; Ludwig-Maximilian Munich Institute, Munich, Germany; the Center of Archaeology of Kurt Engelhorn, Mannheim, Germany and others.

Studies of the West Siberian archaeological detachment, which were carried out over the recent two decades, have provided new data that develop existing points of view, clarify existing concepts or allow to build new concepts of historical and cultural processes. It is obvious that the modern paradigm of science requires participation of specialists in natural sciences at all stages of archaeological research.
bioinspired catalyst systems for selective hydrocarbon oxofunctionalizations based on dinuclear ferric complexes with TPA* and PDP* aminopyridine ligands, hydrogen peroxide, and acetic acid

Using very low temperatures, −75 to −85 °C, the extremely unstable and reactive iron–oxygen intermediates, directly reacting with olefins even at −85 °C, have been detected for the first time. Their EPR parameters (g1 = 2.070–2.071, g2 = 2.005–2.008, g3 = 1.956–1.960) were very similar to those of the known oxoiron(V) complex [(TMC)FeV═O(NC(O)CH3)]+

On the basis of EPR and reactivity data, the detected intermediates were assigned to the FeV═O active oxidizing species of the catalyst systems studied
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192–307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47–52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
We present measurements of B+→¯¯¯D*0τ+ντ and B+→¯¯¯D0τ+ντ decays in a data sample of 657×106 B¯¯¯B pairs collected with the Belle detector at the KEKB asymmetric-energy e+e− collider. We find 446+58−56 B+→¯¯¯D*0τ+ντ events with a significance of 8.1 standard deviations, and 146+42−41 B+→¯¯¯D0τ+ντ events with a significance of 3.5 standard deviations. The latter signal provides the first evidence for this decay mode. The measured branching fractions are B(B+→¯¯¯D*0τ+ντ)=(2.12+0.28−0.27(stat)±0.29(syst))% and B(B+→¯¯¯D0τ+ντ)=(0.77±0.22(stat)±0.12(syst))%.Received 13 May 2010DOI:https://doi.org/10.1103/PhysRevD.82.072005© 2010 The American Physical Society
Sample preconcentration is an important step that increases the accuracy of subsequent detection, especially for samples with extremely low concentrations. Due to the overlapping of electrical double layers in the nanofluidic channel, the concentration polarization effect can be generated by applying an electric field. Therefore, a nonlinear electrokinetic flow is induced, which results in the fast accumulation of proteins in front of the induced ionic depletion zone, the so-called exclusion-enrichment effect.

Nanofractures were created in this work to preconcentrate proteins via the exclusion-enrichment effect. The protein sample was driven by electroosmotic flow and accumulated at a specific location. The preconcentration chip for proteins was fabricated using simple standard soft lithography with a polydimethylsiloxane replica. Nanofractures were formed by utilizing nanoparticle-assisted electric breakdown. The proposed method for nanofracture formation that utilizes nanoparticle deposition at the junction gap between microchannels greatly decreases the required electric breakdown voltage.

The experimental results indicate that a protein sample with an extremely low concentration of 1 nM was concentrated to 1.5×104-fold in 60 min using the proposed chip.
The broad-scale environment plays a substantial role in shaping modern marine ecosystems, but the degree to which palaeocommunities were influenced by their environment is unclear. To investigate how broad-scale environment influenced the community ecology of early animal ecosystems we employed spatial point process analyses to examine the community structure of seven bedding-plane assemblages of late Ediacaran age (558–550 Ma), drawn from a range of environmental settings and global localities. The studied palaeocommunities exhibit marked differences in the response of their component taxa to sub-metre-scale habitat heterogeneities on the seafloor. Shallow-marine palaeocommunities were heavily influenced by local habitat heterogeneities, in contrast to their deep-water counterparts. Lower species richness in deep-water Ediacaran assemblages compared to shallow-water counterparts across the studied time-interval could have been driven by this environmental patchiness, because habitat heterogeneities correspond to higher diversity in modern marine environments. The presence of grazers and detritivores within shallow-water communities may have promoted local patchiness, potentially initiating a chain of increasing heterogeneity of benthic communities from shallow to deep-marine depositional environments. Our results provide quantitative support for the “Savannah” hypothesis for early animal diversification – whereby Ediacaran diversification was driven by patchiness in the local benthic environment. Author Contributions E. Mitchell conceived this paper and wrote the first draft. N. Bobkov, A. Kolesnikov, N. Sozonov and D. Grazhdankin collected the data for DS surface. N. Bobkov and N. Sozonov performed the analyses on DS surface. N. Bykova, S. Xiao, and D. Grazhdankin collected the data for WS, KH1 and KH2 surfaces and E. Mitchell performed the analyses. A. Dhungana and A. Liu collected the data for FUN4 and FUN5 surfaces and A. Dhungana performed the analyses. T. Mustill and D. Grazhdankin collected the data for KS and T. Mustill and E. Mitchell performed the analyses. I. Hogarth developed the software for preliminary KS surface analyses. E. Mitchell, N. Bobkov, N. Bykova, A. Dhungana, A. Kolesnikov, A. Liu, S. Xiao and D. Grazhdankin discussed the results and prepared the manuscript.
In 1992In -2000, new e + e -→ hadrons data were collected in the energy range 0.36 < √ s < 1.4 GeV with the CMD-2 and SND detectors at the VEPP-2M collider in Novosibirsk.

The status of the R(s) measurement by the CMD-2 group is presented.
The work presented describes a combined approach to the partial extraction of the argumentative structure of a text that can be employed in the absence of sufficient annotated data to apply efficiently the machine learning methods for the direct detection of arguments and their relations. In this case, argument identification is performed by using the patterns of argumentation indicators created by a linguist and automatically expanded. These patterns enable the recognition of specific argument types with fine precision. In this study, arguments “from expert opinion” serve as such a pivot type. Besides, potential relations between recognized arguments are analyzed by dividing the text into superphrasal units (fragments united by one topic). The criterion for connecting arguments in an argumentative structure is their inclusion in the same superphrasal unit. An experiment for identifying potentially related arguments is conducted on a set of popular science texts with a minimum size of 1000 words.
The response of extra-tropical evergreen and deciduous Russian forest ecosystems to a wide range of atmospheric background conditions is considered. This study is performed by using a land-surface model, JSBACH. Two numerical experiments are carried out: with hotter and more humid (model PLASIM) and more moderate (model INMCM4) atmospheric background conditions. A perturbation in the climate system is set by using the RCP 8.5 climate scenario. The study has shown a geographical redistribution of the extra-tropical evergreen and deciduous forests across Russia as well as an increase in their fractions in some already forested regions. An increase in the gross and net CO 2 assimilation and respiration of these types of forest vegetation, as their response to the climatic disturbances, is obtained. However, even under the conditions of extremely intense climatic disturbances the Russian forest ecosystems will continue to act as CO 2 sinks.
El objetivo del estudio fue desarrollar un mapa físico preliminar de polimorfismos de nucleótido simple (PNSs) en alpaca usando un panel celular híbrido irradiado alpaca/hámster y una micromatriz de genotipado de alta densidad de bovino (BovineHD BeadChip-Illumina). Se realizó el genotipado de 92 clones celulares híbridos irradiados y cuatro muestras control (alpaca macho, alpaca hembra, hámster y 1:10 alpaca/hámster mezcla de ADN) con la micromatriz. Luego del genotipaje de las muestras control del ADN de alpaca y hámster solo se retuvieron PNSs de bovinos que mostraron una frecuencia de señal positiva de 1. Los PNSs identificados en el ADN de alpaca fueron filtrados para sustraer los presentes en el hámster. De estos últimos, solo se retuvieron para el análisis final aquellos que tuvieron una frecuencia de señal positiva de 0.2 a 0.8 para los 92 clones y se eliminaron los PNSs que presentaron falsos positivos. Los restantes PNSs específicos de alpaca fueron tabulados en el formato MapMaker y fueron analizados con el programa Carthagene para identificar grupos de ligamiento. Los grupos ligados fueron ubicados en el genoma referencial Vicugna_pacos-2.0.2, aplicando el programa BLAST y el comando SHORTBLAST, en la plataforma Galaxy. Las dos muestras control de alpaca registraron 294 165 PNSs, con señal positiva en la micromatriz de bovino. La cantidad de PNSs de alpaca, después de eliminar los PNSs positivos comunes con hámster, fue 50 686 y luego de eliminar los posibles falsos positivos quedaron 2924 PNSs. Esta cantidad se analizó con el programa Carthagene y resultó en 33 grupos de ligamiento, con un total de 216 PNSs. Las distancias calculadas entre estos PNSs oscilan entre 65.3 y 671.9 cR, con un logaritmo de probabilidades (LOD) >6.0. Finalmente, se encontraron un total de 31 PNSs en el genoma referencial (E-value<0.05).
1 НИИ клинической и экспериментальной лимфологиифилиал ФИЦ Институт цитологии и генетики СО РАН 630060, г.Новосибирск, ул.Тимакова, 2 2 НИИ фармакологии и регенеративной медицины им.Е.Д.Гольдберга Томского национального исследовательского медицинского центра 634028, г
We summarized the primary events of researching rock graphic arts compositions in mountains, particularly those located in the northern part of the Kyrgyz Republic.

The article analyzes in details two small petroglyphic compositions with human figures and hoofed animals made in the technique of dotted engraving on rocky ridges, which were discovered in the mountains of Kara-Too, a part of the mountain range of Tian Shan in Kyrgyzstan, and provides a brief description of another similar composition.

The images of humans and animals in the petroglyphic composition of Kara-Too, which were described in the article, apparently relate to the Late Bronze Age and Early Iron Age.
Based on data corresponding to an integrated luminosity of 0.37 fb^-1 collected by the LHCb experiment in 2011, the following ratios of branching fractions are measured: B(B0 -> pi+ pi-) / B(B0 -> K+pi-) = 0.262 +/- 0.009 +/- 0.017, (fs/fd) * B(Bs -> K+K-) / B(B^0 -> K+pi-) = 0.316 +/- 0.009 +/- 0.019, (fs/fd) * B(Bs ->pi+ K-) / B(B0 -> K+pi-) = 0.074 +/- 0.006 +/- 0.006, (fd/fs) * B(B0 -> K+K-) / B(Bs -> K+K-) = 0.018 {+ 0.008 - 0.007} +/- 0.009, (fs/fd) * B(Bs -> pi+pi-) / B(B0 -> pi+pi-) = 0.050 {+ 0.011 - 0.009} +/- 0.004, B(Lambda_b -> p pi-) / B(Lambda_b -> p K-) = 0.86 +/- 0.08 +/- 0.05, where the first uncertainties are statistical and the second systematic. Using the current world average of B(B0 -> K+pi-) and the ratio of the strange to light neutral B meson production fs/fd measured by LHCb, we obtain: B(B0 -> pi+pi-) = (5.08 +/- 0.17 +/- 0.37) x 10^-6, B(Bs -> K+K-) = (23.0 +/- 0.7 +/- 2.3) x 10^-6, B(Bs -> pi+K-) = (5.4 +/- 0.4 +/- 0.6) x 10^-6, B(B0 -> K+K-) = (0.11 {+ 0.05 - 0.04} +/- 0.06) x 10^-6, B(Bs -> pi+pi-) = (0.95 {+ 0.21 - 0.17} +/- 0.13) x 10^-6. The measurements of B(Bs -> K+K-), B(Bs -> pi+ K-) and B(B0 -> K+K-) are the most precise to date. The decay mode Bs -> pi+pi- is observed for the first time with a significance of more than 5 sigma.
To study the effects of decreased amounts or absence of aldosterone on development and endocrine function, we have disrupted the mouse gene, Cyp11b2, coding for aldosterone synthase (AS) by replacing its first two exons with sequences coding for enhanced green fluorescent protein. The null pups fail to thrive postnatally, and about 30% die between d 7 and 28. Aldosterone in plasma and AS mRNA in adrenal glands are undetectable in the null mice. Adult AS-null mice are small, weigh 75% of wild type, are hypotensive, have increased concentrations of plasma K(+) and corticosterone, and a decreased concentration of plasma Cl(-). Their plasma renin and angiotensin II concentrations are 45x and 4x wild type. The adrenal cortex is disorganized and has cells that contain marked accumulations of lipid. The zona glomerulosa is widened and includes easily detectable renin-containing cells, not seen in the wild-type adrenal gland. In the AS-/- adrenals, the level of mRNA for Cyp11b1, coding for 11beta-hydroxylase, is 150% wild type. The adrenal glands of the null mice consequently show evidence of a greatly activated renin-angiotensin system and up-regulation of glucocorticoid production. In the AS-null mice enhanced green fluorescent protein fluorescence is mainly at the boundary between the cortex and medulla, where apoptotic cells are numerous. These data are consistent with the absence of aldosterone in the AS-null mice inducing an increased cell-turnover of cells in the adrenals that normally become AS expressing and their migration to the medullary boundary where they apoptose.
Objective To determine the 23-year trends 1994-2016 yy of adherence towards cardiovascular diseases prevention, behavioral characteristics and awareness about the health in general female population aged 25-44 years in Russia / Siberia. Methods Under the third screening of the WHO program MONICA and sub-program ’MONICA-psychosocial’ (MOPSY) random representative sample of women aged 25-64 years (n = 870) were surveyed in Novosibirsk in 1994; 284 persons in group 25-44y. In 2016 within the framework of the screening studies covered by state task reg.# 01201282292 a random representative sample of women aged 25-44 years was examined in the same district of Novosibirsk (n = 540). Questionnaire MOPSY ‘Awareness and attitude towards the health’ was used to estimate adherence towards cardiovascular diseases prevention, behavioral characteristics and awareness about the health. Results The analysis showed there is a positive trend in self-rated health in female population aged 25-44 years. Despite this 50% of women rate their health negatively and 96% consider the existence of high chance to be ill with serious disease within next 5-10 years. Majority of women believed in the possibilities of modern medicine for the prevention of heart disease but there is extremely low level of healthcare utilization as prevention measure and it doesn’t exceed 10% in those women (p &lt; 0.05). There is a growth of job stress levels and upward trends in family status changes over 23 years in an open population of women aged 25-44 years. Some changes in behavioral status were found over 1994-2016 yy: increased share of people quit smoking and doing regular physical exercises, improved diet behavior. Conclusions We showed a positive trend in CVD risk factors prevention in women 25-44y. In spite of this, half of the women negatively evaluate their health and using of healthcare resources is deficient. There are adverse changes in the social gradient over the follow-up period. Key messages The purpose of this survey was to study the trends in awareness and attitudes towards cardiovascular prevention over 28 years (from 1988 to 2016) in an open female population of 25-44 years old. The purpose of this survey was to study the trends in awareness and attitudes towards cardiovascular prevention over 28 years (from 1988 to 2016) in an open female population of 25-44 years old.
This is data on the microbial diversity of a geothermal spring located on the banks of the acidic creek of Kunashir Island. Data was obtained using 16s rRNA amplicon directed metagenomic sequencing on Illumina MiSeq. The raw sequence data used for analysis is available in NCBI under the Sequence Read Archive (SRA) with the BioProject No. PRJNA637298, PRJNA637447 and SRA accession number SRP265942, SRP266050. The data sequences of the 16s rRNA gene are presented at the accession numbers MT604934-MT604967, MT604911-MT604921 in NCBI GenBank database.