Hengzongshu/ArticleAgent huggingface dataset:
This study reviews the modern knowledge about the electronic properties of oxygen vacancies in the hafnia. Hafnia is a key dielectric for use in the modern electronics.

Oxygen vacancies in the hafnia largely determine its electronic properties. It is shown that electronic transitions to states, localized on the oxygen vacancies, determine the optical properties. The oxygen vacancies act as traps in the charge transport via hafnia films.

It is demonstrated that the hafnium oxide conductivity is limited by phonon assisted tunneling between traps that are the oxygen vacancies.
ABSTRACT The Nuclear Pore Complex (NPC) regulates nucleocytoplasmic transport by providing small channels for passive diffusion and multiple docking surfaces that lead to a central translocation channel for active transport. In this study we have investigated by high resolution scanning and transmission electron microscopy the dynamics of NPC structure in salivary gland nuclei from Chironomus during Balbiani ring (BR) mRNP translocation, and present evidence of rearrangement of the transporter related to mRNP export. Analysis of the individual NPC components verified a strong evolutionary conservation of NPC structure between vertebrates and invertebrates. The transporter is an integral part of the NPC and is composed of a central short double cylinder that is retained within the inner spoke ring, and two peripheral globular assemblies which are tethered to the cytoplasmic and nucleoplasmic coaxial rings by eight conserved internal ring filaments. Distinct stages of BR mRNP nuclear export through the individual NPC components were directly visualized and placed in a linear transport sequence. The BR mRNP first binds to the NPC basket, which forms an expanded distal basket ring. In this communication we present stages of BR mRNP transport through the nucleoplasmic, central and cytoplasmic transporter subunits, which change their conformation during mRNP translocation, and the emegence of mRNP into the cytoplasm. We propose that the reorganization of the basket may be driven, in part, by an active translocation process at the transporter. Furthermore, the images provide dramatic evidence that the transporter functions as a central translocation channel with transiently open discrete gates in its globular assemblies. A model of NPC transporter reorganization accompanied with mRNP translocation is discussed.
We say that a finite almost simple $G$ with socle $S$ is admissible (with respect to the spectrum) if $G$ and $S$ have the same sets of orders of elements. Let $L$ be a finite simple linear or unitary group of dimension at least three over a field of odd characteristic. We describe admissible almost simple groups with socle $L$. Also we calculate the orders of elements of the coset $L\tau$, where $\tau$ is the inverse-transpose automorphism of $L$.
The spectrum ω(G) is the set of orders of elements of a nite group G.We consider the problem of generating the spectrum of a nite nonabelian simple group G given by the degree of G if G is an alternating group, or the Lie type, Lie rank and order of the underlying eld if G is a group of Lie type.
We present a precise measurement of the CP violation parameter sin2phi_1 and the direct CP violation parameter A_f using the final data sample of 772x10^6 B\bar B pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider.

One neutral B meson is reconstructed in a J/psi K0S, psi(2S) K0S, chi_c1 K0S or J/psi K0L CP-eigenstate and its flavor is identified from the decay products of the accompanying B meson. From the distribution of proper time intervals between the two B decays,

we obtain the following CP violation parameters: sin2phi_1=0.667+-0.023(stat)+-0.012(syst) and A_f=0.006+-0.016(stat)+-0.012(syst).
The genus Macrostomum represents a diverse group of rhabditophoran flatworms with >200 species occurring around the world. Earlier we uncovered karyotype instability linked to hidden polyploidy in both M. lignano (2n = 8) and its sibling species M. janickei (2n = 10), prompting interest in the karyotype organization of close relatives.

In this study, we investigated chromosome organization in two recently described and closely related Macrostomum species, M. mirumnovem and M. cliftonensis, and explored karyotype instability in laboratory lines and cultures of M. lignano (DV1/10, 2n = 10) and M. janickei in more detail. We revealed that three of the four studied species are characterized by karyotype instability, while M. cliftonensis showed a stable 2n = 6 karyotype. Next, we performed comparative cytogenetics of these species using fluorescent in situ hybridization (FISH) with a set of DNA probes (including microdissected DNA probes generated from M. lignano chromosomes, rDNA, and telomeric DNA). To explore the chromosome organization of the unusual 2n = 9 karyotype discovered in M. mirumnovem, we then generated chromosome-specific DNA probes for all chromosomes of this species.

Similar to M. lignano and M. janickei, our findings suggest that M. mirumnovem arose via whole genome duplication (WGD) followed by considerable chromosome reshuffling. We discuss possible evolutionary scenarios for the emergence and reorganization of the karyotypes of these Macrostomum species and consider their suitability as promising animal models for studying the mechanisms and regularities of karyotype and genome evolution after a recent WGD.
We report new paleomagnetic data from the ~1108 Ma intrusive Coldwell Complex (Ontario, Canada) to investigate the apparent reversal asymmetry observed in some Midcontinent Rift (MCR) rocks. The rocks of eastern and central part of the complex are reversely magnetized with a group mean direction of D = 114.8°, I = −63.7° ( α 95 = 3.6°, N = 30). The corresponding paleomagnetic pole at P lat = 47.2°N, P long = 206.5°E ( A 95 = 4.8°) is located close to the paleomagnetic poles from nearly coeval reversely magnetized rocks of the MCR system, including the lower lava flows at Mamainse Point. The rocks of western part of the complex are normally magnetized with a group mean direction ( D = 298.0°, I = 56.9°, α 95 = 5.8°, N = 10) that passes the reversal test with respect to the reversed group mean direction. Our results do not support the previous model in which the complex was emplaced during two periods of reversed geomagnetic field polarity separated by a period of normal polarity and hence encompasses two geomagnetic reversals. Instead, our new data indicate that the Coldwell Complex records only two polarity intervals separated by a symmetrical reversal at ~1102–1105 Ma. This reversal is likely equivalent to the lowermost reversal recorded at Mamainse Point and provides further evidence that the apparent reversal asymmetry reflects a plate motion rather than a persistent nondipole field geometry. Together with a high‐quality data from the ~1098 Ma North Shore Volcanics, our data indicate a rapid velocity of Laurentia at ~25 ± 4 cm/yr. The fast plate motion may reflect a decreased mantle drag due to vigorous mantle indicated by widespread intraplate magmatism at ~1.1 Ga.
This paper revisits the problem of tidal conversion at a ridge in a uniformly stratified fluid of limited depth using measurements of complex-valued added mass. When the height of a sub-marine ridge is non negligible with respect to the depth of the water, the tidal conversion can be enhanced in the supercritical regime or reduced in the subcritical regime with respect to the large depth situation. Tidal conversion can even be null for some specific cases. Here, we study experimentally the influence of finite depth on the added mass coefficients for three diffierent ridge shapes. We first show that at low forcing frequency the tidal conversion is weakly enhanced by shallow depth for a semi-circular ridge. In addition, added mass coefficients measured for a vertical ridge show strong similarities with the ones obtained for the semi-circular ridge. Nevertheless, the enhancement of the tidal conversion at low forcing frequency for the vertical ridge has not been observed, in contrast with its supercritical shape. Finally, we provide the experimental evidence of a lack of tidal conversion due to the specific shape of a ridge for certain depth and frequency tuning.
Summary The dominant gene Fused ( Fu ) produces skeletal abnormalities during embryonic development. It was previously shown that C57BL/6 mice contain a suppressor of Fu , which acts after fertilization. Chimaeras were used to study whether this gene would suppress the Fu phenotype after the 8-cell stage of embryo development. We found no effect of the suppressor gene on Fu phenotype (its degree and frequency of expression) in chimaeric mice. We conclude that either the suppressor gene from C57BL/6 mice can only influence Fu expression at the intracellular level or Fu expression is determined before the 8-cell embryonic stage.
In previous work it was demonstrated that decomposition rates of hydrates suspensions in oil at static conditions can be limited by the self-preservation phenomenon.

Impact of different parameters on the decomposition rates of hydrate at negative temperatures with depressurisation method has been studied.

Our experimental research shows that appearance of self-preservation depends on many parameters such as components composition of oil, presence of shear in the system while decomposing hydrates and probably on the history of the sample.
Let G be a finite group and let π be a set of primes.

We prove that G has a solvable π-Hall subgroup if and only if G has a {p, q}-Hall subgroup for every pair p, q ∈ π.

G has a solvable π-Hall subgroup if and only if G has a {p, q}-Hall subgroup for every pair p, q ∈ π.
The article is devoted to the development of new knowledge generation methods based on the analysis of natural language texts.

To extract knowledge from natural language texts, the method of presenting sentences in the form of binary predicates with new constant-situation is used. For the representation of knowledge in a formal form, we use quantifier-free sentences of predicate logic, as well as the OWL DL language. The generation of new knowledge is realized with the help of reasoners, using pre-defined patterns of inference rules.

A software system has been developed that allows users to get answers to specific questions related to given natural language texts. The answers are built in a natural language, using not only the knowledge that is explicitly contained in the document being processed, but also the knowledge generated by the reasoners.
Plastids and mitochondria have their own small genomes which do not undergo meiotic recombination and may have evolutionary fate different from each other and nuclear genome, thus highlighting interesting phenomena in plant evolution.

We for the first time sequenced mitochondrial genomes of pea ( Pisum L.), in 38 accessions mostly representing diverse wild germplasm from all over pea geographical range. Six structural types of pea mitochondrial genome were revealed. From the same accessions, plastid genomes were sequenced. Bayesian phylogenetic trees based on the plastid and mitochondrial genomes were compared. The topology of a phylogenetic tree based on the nucleotide sequence of a nuclear gene His5 coding for a histone H1 subtype corresponds to the current taxonomy and resembles that based on the plastid genome.

The topologies of these trees were highly discordant implying not less than six events of hybridisation of diverged wild peas in the past, with plastids and mitochondria differently inherited by the descendants. Such discordant inheritance of organelles is supposed to have been driven by plastid-nuclear incompatibility, known to be widespread in pea wide crosses and apparently shaping the organellar phylogenies. Wild peas ( Pisum sativum subsp. elatius s.l.) inhabiting Southern Europe were shown to be of hybrid origin resulting from crosses of peas similar to those presently inhabiting south-east and north-east Mediterranean in broad sense.
The rat represents an important animal model that, in many respects, is superior to the mouse for dissecting behavioral, cardiovascular and other physiological pathologies relevant to humans. Derivation of induced pluripotent stem cells from rats (riPS) opens the opportunity for gene targeting in specific rat strains, as well as for the development of new protocols for the treatment of different degenerative diseases. Here, we report an improved lentivirus-based hit-and-run riPS derivation protocol that makes use of small inhibitors of MEK and GSK3. We demonstrate that the excision of proviruses does not affect either the karyotype or the differentiation ability of these cells. We show that the established riPS cells are readily amenable to genetic manipulations such as stable electroporation. Finally, we propose a genetic tool for an improvement of riPS cell quality in culture. These data may prompt iPS cell-based gene targeting in rat as well as the development of iPS cell-based therapies using disease models established in this species.
The evolutionary history of organisms with poor dispersal abilities usually parallels geological events. Collisions of the Indian and Arabian plates with Eurasia greatly changed Asian topography and affected regional and global climates as well as biotic evolution. However, the geological evolution of Asia related to these two collisions remains debated.

Here, we used Eranthis , an angiosperm genus with poor seed dispersal ability and a discontinuous distribution across Eurasia, to shed light on the orogenesis of the Qinghai–Tibetan, Iranian and Mongolian Plateaus. Our phylogenetic analyses show that Eranthis comprises four major geographical clades: east Qinghai–Tibetan Plateau clade (I-1), North Asian clade (I-2), west Qinghai–Tibetan Plateau clade (II-1) and Mediterranean clade (II-2). Our molecular dating and biogeographic analyses indicate that within Eranthis , four vicariance events correlate well with the two early uplifts of the Qinghai–Tibetan Plateau during the Late Eocene and the Oligocene–Miocene boundary and the two uplifts of the Iranian Plateau during the Middle and Late Miocene.

The origin and divergence of the Mongolian Plateau taxa are related to the two uplifts of the Mongolian Plateau during the Middle and Late Miocene. Additionally, our results are in agreement with the hypothesis that the central part of Tibet only reached an altitude of less than 2.3 km at approximately 40 Ma. This study highlights that organismal evolution could be related to the formation of the three great Asian plateaus, hence contributing to the knowledge on the timing of the key tectonic events in Asia.
Results of experimental studies of round and plane propane microjet combustion in a transverse acoustic field at small Reynolds numbers are presented in this paper. Features of flame evolution under the given conditions are shown. Based on the new information obtained on free microjet evolution, new phenomena in flame evolution in a transverse acoustic field with round and plane propane microjet combustion are discovered and explained.
The Siberian salamander Salamandrella keyserlingii Dybowski, 1870 is a unique amphibian that is capable to survive long-term freezing at −55 °C. Nothing is known on the biochemical basis of this remarkable freezing tolerance, except for the fact that it uses glycerol as a low molecular weight cryoprotectant. We used 1H-NMR analysis to study quantitative changes of multiple metabolites in liver and hindlimb muscle of S. keyserlingii in response to freezing. For the majority of molecules we observed significant changes in concentrations. Glycerol content in frozen organs was as high as 2% w/w, which confirms its role as a cryoprotectant. No other putative cryoprotectants were detected. Freezing resulted in ischemia manifested as increased concentrations of glycolysis products: lactate and alanine. Unexpectedly, we detected no increase in concentrations of succinate, which accumulates under ischemia in various tetrapods. Freezing proved to be a dramatic stress with reduced adenosine phosphate pool and high levels of nucleotide degradation products (hypoxanthine, β-alanine, and β-aminoisobutyrate). There was also significant increase in the concentrations of choline and glycerophosphocholine, which may be interpreted as the degradation of biomembranes. Thus, we found that freezing results not only in macroscopical damage due to ice formation, but also to degradation of DNA and biomembranes.
The aim of the work was to study the clinical significance of the genetic polymorphism of the adhesion factor - the genetic locus rs602662 FUT2 in Helicobacter pylori-associated diseases.

Methods: The study included 91 patients. The study for the presence of the polymorphic locus rs602662 of the FUT2 gene was carried out by the standard TaqMan PCR method on a 'Real-Time CFX96 Touch' amplifier. The duration of the study was 6 months.

Results: When assessing the contribution of the genotype of the rs602662 locus of the FUT2 gene as a risk factor for the occurrence of clinical manifestations in H. pylori infection, it was found that the A allele has a protective effect on the occurrence of clinical symptoms of dyspepsia. The odds ratio (OR) for allele 'A' carriers (genotypes A/A and G/A versus G/G) to have clinical symptoms with a positive H. pylori status was 0.175 (CI=[0.049-0.625] chi2=7.79 p=0.0053). Conclusion. As a result of the study, it was revealed that the carriage of the 'A' allele has a significant associative relationship with the absence of clinical symptoms in patients with H. pylori infection 0.175 (C.I.= [0.049-0.625] chi2=7.79 p=0.0053).
Hyperpolarized (HP) propane produced by the parahydrogen-induced polarization (PHIP) technique has been recently introduced as a promising contrast agent for functional lung magnetic resonance (MR) imaging. However, its short lifetime due to a spin-lattice relaxation time T1 of less than 1 s in the gas phase is a significant translational challenge for its potential biomedical applications. The previously demonstrated approach for extending the lifetime of the HP propane state through long-lived spin states allows the HP propane lifetime to be increased by a factor of ∼3. Here, we demonstrate that a remarkable increase in the propane hyperpolarization decay time at high magnetic field (7.1 T) can be achieved by its dissolution in deuterated organic solvents (acetone-d6 or methanol-d4). The approximate values of the HP decay time for propane dissolved in acetone-d6 are 35.1 and 28.6 s for the CH2 group and the CH3 group, respectively (similar values were obtained for propane dissolved in methanol-d4), which are ∼50 times larger than the gaseous propane T1 value. Furthermore, we show that it is possible to retrieve HP propane from solution to the gas phase with the preservation of hyperpolarization.
We report direct single-laser excitation of the strictly forbidden (6s2)1S0 (6s6p)3P0 clock transition in 174Yb atoms confined to a 1D optical lattice. A small (approximately 1.2 mT) static magnetic field was used to induce a nonzero electric dipole transition probability between the clock states at 578.42 nm. Narrow resonance linewidths of 20 Hz (FWHM) with high contrast were observed, demonstrating a resonance quality factor of 2.6 x 10(13). The previously unknown ac Stark shift-canceling (magic) wavelength was determined to be 759.35 +/- 0.02 nm. This method for using the metrologically superior even isotope can be easily implemented in current Yb and Sr lattice clocks and can create new clock possibilities in other alkaline-earth-like atoms such as Mg and Ca.
The inclusive top quark pair ($t\bar{t}$) production cross-section $\sigma_{t\bar{t}}$ has been measured in proton$-$proton collisions at $\sqrt{s}=13$ TeV, using $36.1$ fb$^{-1}$ of data collected in 2015$-$16 by the ATLAS experiment at the LHC.

Using events with an opposite-charge $e\mu$ pair and $b$-tagged jets, the cross-section is measured to be: \begin{equation}\nonumber \sigma_{t\bar{t}} = 826.4 \pm 3.6\,\mathrm{(stat)}\ \pm 11.5\,\mathrm{(syst)}\ \pm 15.7\,\mathrm{(lumi)}\ \pm 1.9\,\mathrm{(beam)}\,\mathrm{pb}, \end{equation} where the uncertainties reflect the limited size of the data sample, experimental and theoretical systematic effects, the integrated luminosity, and the LHC beam energy, giving a total uncertainty of 2.4%.

The result is consistent with theoretical QCD calculations at next-to-next-to-leading order. It is used to determine the top quark pole mass via the dependence of the predicted cross-section on $m_t^{\mathrm{pole}}$, giving $m_t^{\mathrm{pole}}=173.1^{+2.0}_{-2.1}$ GeV. It is also combined with measurements at $\sqrt{s}=7$ TeV and $\sqrt{s}=8$ TeV to derive ratios and double ratios of $t\bar{t}$ and $Z$ cross-sections at different energies. The same event sample is used to measure absolute and normalised differential cross-sections as functions of single-lepton and dilepton kinematic variables, and the results compared with predictions from various Monte Carlo event generators.
Such ensembles of strongly interacting atoms in the regime of Rydberg blockade are known as Rydberg superatoms.

We have numerically simulated quantum tomography of single-qubit and two-qubit quantum gates with qubits represented by mesoscopic ensembles containing random numbers of atoms. The stimulated Raman adiabatic passage (STIRAP) in the regime of Rydberg blockade is used for determining Rydberg excitation in the ensemble, required for the storage of quantum information in the collective state of the atomic ensemble and implementation of two-qubit gates. The optimized shapes of the STIRAP pulses are used to achieve high fidelity of the population transfer.

Our simulations confirm the validity and high fidelity of single-qubit and two-qubit gates with Rydberg superatoms.
It was found that high-affinity anti-DNA antibodies were one of the major components of the intrathecal IgG response in multiple sclerosis (MS) patients [Williamson et al., PNAS, 2001]. Recently we have shown that IgGs from the sera of MS patients are active in the hydrolysis of DNA.

Here we have shown, for the first time, that average concentration of total proteins (132-fold), total IgGs (194-fold) and anti-DNA antibodies (200-fold) in the sera is significantly higher than that in the cerebrospinal fluid (CSF) of fifteen MS patients. The relative activities of total protein from sera and CSFs varied remarkably from patient to patient. It was surprising that the specific DNase activity of the total protein of CSF reparations were 198-fold higher than the serum ones. Electrophoretically and immunologically homogeneous IgGs were obtained by sequential affinity chromatography of the CSF proteins on protein G-Sepharose and FPLC gel filtration.

We present first evidence showing that IgGs from CSF not only bind but efficiently hydrolyze DNA and that average specific DNase activity of homogeneous antibodies from CSF is unpredictably ∼49-fold higher than that from the sera of the same MS patients. Some possible reasons of these findings are discussed. We suggest that DNase IgGs of CSF may promote important neuropathologic mechanisms in this chronic inflammatory disorder and MS pathogenesis development.