Hengzongshu/ArticleAgent huggingface dataset:
We also present FISH data showing the distribution of telomeric repeats and 18S rDNA on the chromosomes of these species and the results of similar studies cited in the literature on S. hellenica, S. natoliae, and S. rhodiensis.

We report the karyotype characteristics including chromosome numbers of Saga campbelli campbelli, S. c. gracilis, and S. rammei using the following classical cytogenetic methods: C-banding, silver staining, and fluorochrome staining DAPI and CMA3. In the present study we focused on testing a hypothetical model of karyotype evolution in Saga, with particular reference to the cytogenetic mapping of rDNA and telomeric sequences.

The five European Saga species exhibit a high rate of karyotype evolution. In addition to changes in chromosome number and morphology (by chromosomal inversion and/or chromosome fusion), interspecific autosomal differentiation involved changes in the distribution and quantity of constitutive heterochromatin and GC-rich regions, as well as the number and location of NORs. Variation in the distribution of rDNA and location of Ag-NORs are novel phylogenetic markers for the genus Saga.
Currently, several materials for the closure of the dura mater (DM) defects are known. However, the long-term results of their usage reveal a number of disadvantages. The use of antibiotics and chitosan is one of the major trends in solving the problems associated with infectious after-operational complications.

This work compares the mechanical properties of samples of bacterial nanocellulose (BNC) impregnated with Novochizol™ and vancomycin with native BNC and preserved and native human DM. An assessment of the possibility of controling the mechanical properties of these materials by changing their thickness has been performed by statistical analysis methods. A total of 80 specimens of comparable samples were investigated.

During the analysis, the results obtained, the factor of Novochizol™ addition has provided a statistically significant impact on the strength properties (Fisher Criteria p-value 0.00509 for stress and 0.00112 for deformation). Moreover, a stronger relationship between the thickness of the samples and their ultimate load was shown: R2=0.236 for BNC + Novochizol™ + vancomycin, compared to R2=0.0405 for native BNC. Using factor analysis, it was possible to show a significant effect of modified chitosan (Novochizol™) on the ultimate stress (p-value = 0.005).
This paper is devoted to modeling the properties of composite materials and reinforced composite beams.

Mathematical relations describing the nonlinear elastic three-point bending of isotropic and reinforced beams with account of different strength and stiffness behavior in tension and compression are obtained. An algorithm for numerical solution of corresponding boundary-value problems is proposed and implemented.

Results of numerical analysis were compared to acquired data for polymer matrix and structural carbon fiber reinforced plastics.
The dominant hypothesis about the pathogenesis of Alzheimer’s disease (AD) is the 'amyloid cascade' concept and modulating the expression of proteins involved in the metabolism of amyloid-beta (Aβ) is proposed as an effective strategy for the prevention and therapy of AD. Recently, we found that an antibiotic ceftriaxone (CEF), which possesses neuroprotective activity, reduced cognitive deficits and neurodegenerative changes in OXYS rats, a model of sporadic AD.

The study was aimed to determine the effects of CEF on mRNA levels of Bace1 (encoding β-secretase BACE1 involved in Aβ production), Mme, Ide, Ece1, Ace2 (encoding enzymes involved in Aβ degradation), Epo (encoding erythropoietin related to endothelial function and clearance of Aβ across the blood brain barrier) in the frontal cortex, hippocampus, striatum, hypothalamus, and amygdala of OXYS and Wistar (control strain) male rats. Starting from the age of 14 weeks, animals received CEF (100 mg/kg/day, i.p., 36 days) or saline. mRNA levels were evaluated with RT-qPCR method. Biochemical parameters of plasma were measured for control of system effects of the treatment. To better understand strain variations studied here, we compared the gene expression between untreated OXYS and Wistar rats.

This comparison showed a significant decrease in mRNA levels of Ace2 in the frontal cortex and hypothalamus, and of Actb in the amygdala of untreated OXYS rats. Analysis of potential effects of CEF revealed its novel targets. In the compound-treated OXYS cohort, CEF diminished mRNA levels of Bace1 and Ace2 in the hypothalamus, and Aktb in the frontal cortex. Furthermore, CEF augmented Mme, Ide, and Epo mRNA levels in the amygdala as well as the levels of Ece1 and Aktb in the striatum. Finally, CEF also attenuated the activity of ALT and AST in plasma of OXYS rats. Those findings disclosed novel targets for CEF action that might be involved into neuroprotective mechanisms at early, pre-plaque stages of AD-like pathology development.
Ensuring the safety and high operation reliability of nuclear reactors takes 100% inspection of geometrical parameters of fuel assemblies, which include the grid spacers fabricated as cellular structure with fuel elements. The required grid spacers’ geometry of assembly in the transverse and longitudinal cross sections is extremely important for maintaining the necessary heat regime. A universal method for 3D grid spacer inspection using the diffractive optical element, which generates, as the structured light, a multiple-ring pattern on the inner surface of a grid spacer cell is investigated. The experimental measurement error for cell centers position deviation is ±7 µm, and the error for overall dimensions is ±11 µm.
Patients with brain tumors are at increased risk for the development of venous thromboembolism (VTE). The most effective prevention method today is a combination of mechanical compression of the lower extremities and the introduction of low molecular weight heparin (LMWH). In 2018, an algorithm for the prevention of VTE was introduced in our clinic, which implies the early (in the first 48 h after surgery) administration of LMWH.

From January 2014 to December 2019, 3266 patients underwent removal of brain tumors. The group 1 included 2057 patients who were treated in the period before the introduction of the VTE prevention algorithm (2014– 2017), the group 2 included 1209 patients who were treated using this algorithm (2018–2019). In each of the groups, the frequency and timing of ICH were assessed. The severity of complications was assessed according to the F.A.L. Ibanez classification. The data were compared between groups 1 and 2, as well as between patients who received LMWH at the time of ICH and those who did not receive.

Patients of the group 1 were prescribed LMWH in 14.3 % of cases, on average on the 4th day after surgery. In this group, 26 (1.26 %) patients developed ICH. Patients of the group 2 were prescribed LMWH in 89 % of cases, on average on the 2nd day. In this group, 15 (1.24 %) patients developed ICH. Severe complications were in 6 (85.7 %) of 7 patients who received LMWH at the time of ICH, and in 25 (73.5 %) of 34 patients who did not receive LMWH ( p = 0.66). The widespread use of LMWH for the prevention of VTE during the first 48 h after removal of brain tumors did not lead to an increase in the frequency of ICH. At the same time, patients with ICH who developed during the use of LMWH often had a more severe clinical course.
The generalized hyper-Ramsey resonance formula originally published in Phys. Rev. A vol 92, 023416 (2015) is derived using a Cayley-Klein spinor parametrization. The shape of the interferometric resonance and the associated composite phase-shift are reformulated including all individual laser pulse parameters. Potential robustness of signal contrast and phase-shift of the wave-function fringe pattern can now be arbitrarily explored tracking any shape distortion due to systematic effects from the probe laser. An exact and simple analytical expression describing a Ramsey's method of separated composite oscillating laser fields with quantum state control allows us to accurately simulate all recent clock interrogation protocols under various pulse defects.
This paper reports on an experimental study of the gas (nitrogen) driven water rivulet flow regimes in the minichannel. The width of the liquid nozzle is 10 mm, the height and width of minichannel are 1.61 ±0.02 mm and 30 mm correspondently. The new flow regime has been found by authors. Its occurrence is connected with influence of relatively large static wetting angle of water on the flow and comparably small height of the channel. It was named "rivulet bridge". The paper presents a map of the various rivulet flow regimes, characterized by different geometry and different kinds of surface deformations at temperature 40°C.
In the modern world, globalization leads to the active interaction of representatives of different cultures, however, there are questions of how this is reflected in the well-being level of society. This article raises the problem of the cultural heterogeneity consequences as a result of globalization.

For the analysis, religion was chosen as a cultural feature (criterion of heterogeneity), which is an institution of norms and values of the population, as well as a reflection of the historical past of population. The object of research is the regions of Russia. The analysis used data from the Atlas of Religions and Nationalities of Russia «Arena» (Non-profit research based consulting "Sreda") and the Federal Agency for Ethnic Affairs. The study analyzed the influence of religious heterogeneity on the level of scientific activity of organizations in the regions of the Russian Federation.

The negative influence of religious heterogeneity on the level of research activity of organizations in the regions of the Russian Federation was revealed. It is shown that the impact is not direct. Religious heterogeneity is associated with the level of migration of young scientists, which, in turn, has an impact on the activities of scientific organizations in the country.
In modern conditions of a high level of uncertainty in the development of science, engineering and technology in economic sectors, it is necessary to learn how to manage this long-term process purposefully, which is possible through forecasting tools, for example, foresight methodology. This is especially true for agriculture, and in particular for the crop sector, where the level of uncertainty is much higher than in other sectors due to work with living organisms and the impact on the results of production of natural and climatic conditions. The consistent use of foresight tools made it possible to develop a Strategy for the scientific and technological development of the crop industry for the Novosibirsk region, the algorithm of which is presented in this article. The main feature of the Strategy will be the identification of promising areas of scientific and technological development depending on the natural and agricultural zoning of the region, which allows one to take into account the specifics of different regions of the Novosibirsk region to build a more accurate and high-quality forecast.
Juvenile hormone (JH) and dopamine are involved in the stress response in insects. The insulin/insulin-like growth factor signalling pathway has also recently been found to be involved in the regulation of various processes, including stress tolerance. However, the relationships among the JH, dopamine and insulin signalling pathways remain unclear. Here, we study the role of insulin signalling in the regulation of JH and dopamine metabolism under normal and heat stress conditions in Drosophila melanogaster females. We show that suppression of the insulin-like receptor (InR) in the corpus allatum, a specialised endocrine gland that synthesises JH, causes an increase in dopamine level and JH-hydrolysing activity and alters the activities of enzymes that produce as well as those that degrade dopamine (alkaline phosphatase (ALP), tyrosine hydroxylase (TH) and dopamine-dependent arylalkylamine N-acetyltransferase (DAT)). We also found that InR suppression in the corpus allatum modulates dopamine, ALP, TH and JH-hydrolysing activity in response to heat stress and that it decreases the fecundity of the flies. JH application restores dopamine metabolism and fecundity in females with decreased InR expression in the corpus allatum. Our data provide evidence that the insulin/insulin-like growth factor signalling pathway regulates dopamine metabolism in females of D. melanogaster via the system of JH metabolism and that it affects the development of the neuroendocrine stress reaction and interacts with JH in the control of reproduction in this species.
Композиция на основе оксида алюминия и полидиметилсилоксана -матрица для повышения эффективности доставки лекарственных препаратов
Purpose. This article reflects the program and the main research questions to describe the place of infographics on the media sites of the biggest Siberian cities. On the first stage of the research there were generated the solid sample of the infographics produced by six online media of Novosibirsk, five – of Krasnoyarsk and five – of Omsk. Results. The empirical base shows, chronologically, how the format is penetrated and developed the editorial boards of these media, given the number published on these website infographic in different years, revealed the media who regularly use this format, and media who do it rather rare. It is shown that this format is used by regional media quite selectively, only a few media creates more than a fifteen infographics per year. Nevertheless, the total number of infographics that could be found and included in the empirical base is quite large: more than five hundred infographics. They presents as standalone products in the sections allocated specifically for them, so the form of illustrations for reviews, articles and notes. Conclusions. They presents as standalone products in the sections allocated specifically for them, so the form of illustrations for reviews, articles and notes. At the second stage of the study, the method of content analysis will be applied to the formed empirical base, we also plan to analyze the auditoria indicators of the relevant projects, interview experts in the editorial offices to find out peculiarities of the production process.
The paper is devoted to the study of free objects in the variety of Steiner loops and of the combinatorial structures behind them, focusing on their automorphism groups.

We prove that all automorphisms are tame and the automorphism group is not finitely generated if the loop is more than $3$-generated. For the free Steiner loop with $3$ generators we describe the generator elements of the automorphism group and some relations between them.
We studied the radiative muon decay $μ^+	o e^+νarνγ$ by using for the first time an almost fully polarized muon source.

We identified a large sample (~13000) of these decays in a total sample of 1.8x10^14 positive muon decays collected in the MEG experiment in the years 2009--2010 and measured the branching ratio B($μ^+	o e^+νarνγ$) = (6.03+-0.14(stat.)+-0.53(sys.))x10^-8 for E_e > 45 MeV and E_γ > 40 MeV.

The precise measurement of this decay mode provides a basic tool for the timing calibration, a normalization channel, and a strong quality check of the complete MEG experiment in the search for $μ^+	o e^+γ$ process.
High thermal load applications such as high speed dry cutting lead to high temperatures in the coated tool substrate that can soften the tool and high temperature gradients that can put stress on the coating/tool interface.

In this work, theoretical considerations are presented for multilayer and graded protective coatings that can induce a significant anisotropy in their thermal conductivity. Solution of the heat equation shows that anisotropy of thermal conductivity has the potential to reduce temperatures and temperature gradients arising due to brief, localized heat at the coating surface. Experimental realization of high anisotropy is demonstrated in TiN/AlCrN multilayer coatings with variable layer thickness. Time-domain thermoreflectance is used to measure in-plane and cross-plane thermal conductivity of fabricated coatings.

In the coating with 50 nm bilayer periodicity, the highest anisotropy was obtained with a value of κ||/κ⊥=3.0±0.9. The observed high values of anisotropy of thermal conductivity are compared with theoretical predictions and its realisation is discussed with regard to the coating microstructure.
Features such as the orientation of the graves, their alignment, the position of human remains, and the grave goods in that area are similar to the Andronovo (Fedorovka) burial practice and do not differ from those in other parts of the cemetery. No complete parallels to this rite have been revealed. Some similarities, such as the use of ash, and the presence of animal bones, sacrificial pits, etc. at other sites are listed.

This article summarizes the findings relating to a spatially localized group of graves at the Andronovo (Fedorovka) cemetery Tartas-1 in the Baraba forest-steppe. Several rows of graves combine with ash pits suggestive of ritual activity. In the infill of graves, there were ash lenses with mammal and fish bones, and potsherds with traces showing the signs of applied heat. Ash had been taken from nearby ash pits with similar infill and artifacts. Faunal remains from graves and ash pits (limb bones of cattle, sheep/goat, and horse) indicate sacrificial offerings. In the ash layer of grave No. 282, there was an incomplete human burial, also believed to be a sacrifice.

A reconstruction of the funerary sequence and possible interpretations are considered. It is concluded that those graves were left by a group of Andronovo migrants who maintained close ties with the native population. Unusual features of the burial rite, therefore, can reflect an attempt to consolidate the immigrant groups on the basis of traditional ritual practices, where the major role was played by fire and its symbols.
Liquid phase pentanoic acid hydrogenation in decane as a solvent (180 ºC, hydrogen pressure 25 bar) was studied over monometallic Ir and bimetallic Ir-Re catalysts supported on alumina, ceria and zirconia, as well as carbon support Sibunit.

Before catalytic test all catalysts were preliminary treated in Н 2 at 415 ºC during 5 h.An XPS study revealed predominant metallic state for Ir in studied catalysts while Re was partially oxidized.A series of the most active catalyst IrRe/Al 2 O 3 was prepared varying Ir particle size from 0.8 to 1.7 nm as verified by TEM.

Conversion of pentanoic acid changed in the row Ir/CeO 2 < Ir/ZrO 2 < IrRe/ZrO 2 < IrRe/Al 2 O 3 ~ IrRe/C.Selectivity to pentanol was elevated over bimetallic catalysts in the sequence Ir/Al 2 O 3 < Ir/CeO 2 ~ Ir/ZrO 2 < IrRe/ZrO 2 < IrRe/Al 2 O 3 ~ IrRe/C.It was shown that doping of Ir with Re gives a rise of pentanoic acid conversion and selectivity to pentanol in the absence of byside decarboxylation reaction.Both pentanoic acid conversion and selectivity to pentanol over IrRe/Al 2 O 3 catalyst increased with an increase of mean Ir particle size.
The inverse source problem for 2D advection-diffusion-reaction model with the measurement data in the form of 2D concentration distribution images is considered. These inverse problems arise in the air quality studies with satellite images data avalible.

The sensitivity operator composed of the set of the adjoint problems is used to transform the inverse source problem to the quasi-linear operator equation, which depends on the set of the projection basis functions for the incoming measurement data.

The algorithm is tested in the scenarion for an atmospheric chemistry transport model.
Apatite-type lanthanum silicates (ATLS) materials have attracted interest in recent literature as solid electrolytes for SOFCs. The fabrication of an ATLS based fuel cell with the state-of-art electrodes (NiO/YSZ as anode and LSCF or LSM as cathode) can show degradation after long operation hours due to Si diffusion mainly towards the anode. In this work, we report a "layer-by-layer anodic electrodes" fabrication by means of spin coating and physical spraying. The overall aim of this work is the successful fabrication of such a layered structure including suitable blocking layers towards the inhibition of Si interdiffusion from the apatite electrolyte to the anode. The results showed that the deposition of 3 layers of LFSO/GDC (3μm), NiO/GDC (4μm) and the final NiO/YSZ anode layer provided a stable half-cell, with no solid state reaction occurring among the electrodes and no Si diffusion observed towards the anode after thermal treatment at 800°C for 120h.
We search for the charmless ${B}^{0}$ decay with final state particles $p\overline{\mathrm{$\Lambda${}}}{$\pi${}}^{$-${}}$\gamma${}$ using the full data sample that contains $772\ifmmode\times\else\texttimes\fi{}1{0}^{6}B\overline{B}$ pairs collected at the $\mathrm{$\Upsilon${}}(4S)$ resonance with the Belle detector at the KEKB asymmetric-energy ${e}^{+}{e}^{$-${}}$ collider. This decay is predicted to proceed predominantly via the $b$\rightarrow${}s$\gamma${}$ radiative penguin process with a high energy photon. No significant signal is found. We set an upper limit of $6.5\ifmmode\times\else\texttimes\fi{}1{0}^{$-${}7}$ for the branching fraction of ${B}^{0}$\rightarrow${}p\overline{\mathrm{$\Lambda${}}}{$\pi${}}^{$-${}}$\gamma${}$ at the 90% confidence level.
Cytomixis is a poorly studied process of nuclear migration between plant cells. It is so far unknown what drives cytomixis and what is the functional state of the chromatin migrating between cells.

Using immunostaining, we have analyzed the distribution of posttranslational histone modifications (methylation, acetylation, and phosphorylation) that reflect the functional state of chromatin in the tobacco microsporocytes involved in cytomixis.

We demonstrate that the chromatin in the cytomictic cells does not differ from the chromatin in intact microsporocytes according to all 14 analyzed histone modification types. We have also for the first time demonstrated that the migrating chromatin contains normal structures of the synaptonemal complex (SC) and lacks any signs of apoptosis. As has been shown, the chromatin migrating between cells in cytomixis is neither selectively heterochromatized nor degraded both before its migration to another cell and after it enters a recipient cell as micronuclei. We also showed that cytomictic chromatin contains marks typical for transcriptionally active chromatin as well as heterochromatin. Moreover, marks typical for chromosome condensation, SC formation and key proteins required for the formation of bivalents were also detected at migrated chromatin.
We search for lepton flavor and lepton number violating tau decays into a lepton (ell = electron or muon) and two charged mesons (h,h' = pi^\pm or K^\pm), tau- -> ell-h+h'- and tau- -> ell+h-h'-, using 671 fb^{-1} of data collected with the Belle detector at the KEKB asymmetric-energy e+e- collider. We obtain 90% C.L. upper limits on the branching fractions in the range (4.4-8.8)x10^{-8} for tau -> ehh', and (3.3-16)x10^{-8} for tau -> muhh' processes. These results improve upon previously published upper limits by factors between 1.6 to 8.8.