Hengzongshu/ArticleAgent huggingface dataset:
Life has offered humanity a unique experiment of experience a real threat and an unprecedented reaction to in the form of self-isolation. Media communication has a crucial role in this situation. The research focuses on the analysis of the media sphere dynamics during COVID-19 pandemic on the example of popular local news website. Data on publication activity, views and comments were collected from January 22 to July 19. An unexpected and paradoxical scene is observed. As the epidemiologic situation worsens, journalists write less about COVID-19 and users demonstrate less interest and emotions in this topic too. It was revealed that user reactions are mostly caused by messages about lockdown, bans and restrictive measures rather than on the epidemiologic reports and details. The article discusses two periods which are characterized by different behavior if users and journalists. At first, the unique uncertainty situation generates great interest and emotional response to information about coronavirus. So, users and authors are guided by news about pandemic from Europe and China. Later understanding of possible risks displaces interest in the topic and reduce the degree of emotions. Moscow context becomes a guide in perception of pandemic as a stressful situation. In none of these periods the local epidemiological situation didn`t play a crucial role in determining of the reaction of the media sphere. Qualitative analysis of comments revealed high user aggression, especially during the first months of coronavirus pandemic. Also, three groups of commentators were identified which differ in their attitudes towards the problem of coronavirus.
Differential proteomic analysis of the total E.coli protein after exposure to terahertz (THz) radiation was performed.

Glutamine synthetase was one of the proteins overexpressed in response to THz radiation. E.coli/pGlnA-GFP biosensor based on the promoter of the glnA gene and the GFP protein was constructed and there was demonstrated that it could detect THz radiation.

Such a method of design of biosensors which includes cell irradiation, omics analysis of differential expression of genes, the definition of the most pronounced gene can be used for any region of the electromagnetic spectrum.
Marxism and the theory of post-industrial society are two competing but largely similar approaches to the interpretation of social development.

The emergence of the hypothesis of the transition to a new, post-industrial stage of history was a challenge for Marxist theorists. They responded with a series of arguments, more or less valid, attempting to refute the main tenets of the competing theory.

By now, the dispute is not over. However, it became clear that the key points of both approaches needed further justification.
Eingeschlossene Kohlenstoffspezies spielen eine doppelte Rolle in der nichtoxidativen Dehydroaromatisierung von Methan über Mo-Atom/ZSM-5-Katalysatoren. In ihrer Zuschrift auf S. 1028 zeigen N. Kosinov, E. J. M. Hensen et al. mithilfe von Operando-Spektroskopie, Mikroskopie und Isotopenmarkierung von Methan, dass polycyclische aromatische Kohlenwasserstoffe, die in den Mikroporen des Zeolith-Katalysators entstehen, entscheidende Zwischenstufen auf dem Weg zu Benzol sind. Diese Spezies desaktivieren den Katalysator durch Bildung von Ablagerungen, die den Zugang zu den Poren versperren.
The free-living flatworm Macrostomum lignano is a model organism for evolutionary and developmental biology studies. Recently, an unusual karyotypic diversity was revealed in this species. Specifically, worms are either 'normal' 2n = 8, or they are aneuploid with one or two additional large chromosome(s) (i.e. 2n = 9 or 2n = 10, respectively). Aneuploid worms did not show visible behavioral or morphological abnormalities and were successful in reproduction. In this study, we generated microdissected DNA probes from chromosome 1 (further called MLI1), chromosome 2 (MLI2), and a pair of similar-sized smaller chromosomes (MLI3, MLI4). FISH using these probes revealed that MLI1 consists of contiguous regions homologous to MLI2-MLI4, suggesting that MLI1 arose due to the whole genome duplication and subsequent fusion of one full chromosome set into one large metacentric chromosome. Therefore, one presumably full haploid genome was packed into MLI1, leading to hidden tetraploidy in the M. lignano genome. The study of Macrostomum sp. 8 - a sibling species of M. lignano - revealed that it usually has one additional pair of large chromosomes (2n = 10) showing a high homology to MLI1, thus suggesting hidden hexaploidy in its genome. Possible evolutionary scenarios for the emergence of the M. lignano and Macrostomum sp. 8 genomes are discussed.
The results for the form factor are compared with the predictions based on pQCD and VMD.

The results are obtained by using the full data set of about 470 fb −1 collected by the BABAR experiment at the PEP-II e + e − collider at a center-of-mass energy of about 10.6 GeV.

We report the results on the channels e + e − → π + π − π 0 π 0 π 0 (η), e + e − → π + π − η. Also we present the study of the two-photon process e + e − → e + e − η ' in the double-tag mode.
Chromosomal races of the common shrew differ in sets of metacentric chromosomes and on contact may produce hybrids with extraordinarily complex configurations at meiosis I that are associated with reduced fertility. There is an expectation that these may be some of the most extreme tension zones available for study and therefore are of interest as potential sites for reproductive isolation. Here, we analyse one of these zones, between the Novosibirsk race (characterized by metacentrics go , hn , ik , jl , mp and qr ) and the Tomsk race (metacentrics gk , hi , jl and mn and acrocentrics o , p , q and r ), which form hybrids with a chain‐of‐nine (CIX) and a chain‐of‐three (CIII) configuration at meiosis I. At the Novosibirsk–Tomsk hybrid zone, the CIX chromosomes form clines of 8.53 km standardized width on average, whereas the cline for the CIII chromosomes was 52.83 km wide. The difference in these cline widths fits with the difference in meiotic errors expected with the CIX and CIII configuration, and we produce estimates of selection against hybrids with these types of configurations, which we relate to dispersal and age of the hybrid zone. The hybrid zone is located at the isocline at 200 m altitude above sea level; this relationship between the races and altitude is suggested at both coarse and fine scales. This indicates adaptive differences between the races that may in turn have been promoted by the chromosome differences. Thus, the extreme chromosomal divergence between the Novosibirsk and Tomsk may be associated with genic differentiation, but it is still striking that, despite the large chromosomal differences, reproductive isolation between the Novosibirsk and Tomsk races has not occurred.
The model is developed and the boundary condition is approximated at the lower boundary of the channel.

It is shown that a hydrophobic surface can significantly reduce the hydraulic resistance due to the occurrence of bubble layer. Moreover, at the slip ratio equal to 1 mm, the water flow rate in the channel with the height of 1 mm increases by 2.5 times.
It has been established previously that up to 40% of mouse CD34+ hematopoietic stem cells are capable of internalizing exogenous dsDNA fragments both in vivo and ex vivo. Importantly, when mice are treated with a combination of cyclophosphamide and dsDNA, the repair of interstrand crosslinks in hematopoietic progenitors is attenuated, and their pluripotency is altered.

Here we show for the first time that among various actively proliferating mammalian cell populations there are subpopulations capable of internalizing dsDNA fragments. In the context of cancer, such dsDNA-internalizing cell subpopulations display cancer stem cell-like phenotype. Furthermore, using Krebs-2 ascites cells as a model, we found that upon combined treatment with cyclophosphamide and dsDNA, engrafted material loses its tumor-initiating properties which we attribute to the elimination of tumor-initiating stem cell subpopulation or loss of its tumorigenic potential.

In the context of cancer, such dsDNA-internalizing cell subpopulations display cancer stem cell-like phenotype. Furthermore, using Krebs-2 ascites cells as a model, we found that upon combined treatment with cyclophosphamide and dsDNA, engrafted material loses its tumor-initiating properties which we attribute to the elimination of tumor-initiating stem cell subpopulation or loss of its tumorigenic potential.
The problems raised in the paper are considered in the context of basic trends in the evolution of borders of the states belonging to the former Soviet zone of influence that occurred in Europe and Eurasia after collapse of the USSR. The vectors of evolution of borders of the Central and Eastern Europe countries and Commonwealth of Independent States are analyzed.

Methodologically, the article is based on the ''New economic geography'' approaches and the theory of borders by O Martinez with the accents made on the institutional factors of the cross-border cooperation.

According to the authors' view, the current state of interregional cooperation is not satisfactory to stimulate the process of regional development and integration and cannot substitute the advantages of cross-border cooperation of the «euroregions» type. So far, the authors conclude that no cross-border regions exist in Russia -Kazakhstan border area meaning that there are no genuine integrated regions. They agree that comparative advantages of the cross-border localization and available resources in a poor institutional environment can turn into barriers for regional development and, therefore, transform into «institutional traps».
The novel microwave quasi-elliptic bandstop filter, which uses the initially uncoupled strip transmission lines, is considered in this work. The proposed filter is based on the reentrant structure, where the metallic body with a floating potential is asymmetric. Generally speaking, the internal and external dielectric fillings must have their unequal relative permittivities. As a result, additional symmetrical reflection zeros are reached at the lower and upper pass bands of the stop band leading to the quasi-elliptic function response that improves the filter selectivity. The general transverse electromagnetic (TEM) circuit model for the proposed filter in terms of a series connection of the multi-ports is presented and then used to predict the initial electrical and geometrical parameters. An experimental printed circuit prototype has been manufactured and evaluated to validate the design concept. The measured filter parameters correlate well with the simulation-derived ones and that increases the degree of freedom in the fabrication of microwave frequency selective components.
Testis growth during early life is important for future male fertility and shows acceleration during the first months of life in humans. This acceleration coincides with the peak in gonadotropic hormones in the blood, while the role of hypothalamic factors remains vague. Using neonatal rats to assess this issue, we found that day 9 of life is likely critical for testis development in rats. Before this day, testicular growth was proportional to body weight gain, but after that the testes showed accelerated growth. Hypothalamic kisspeptin and its receptor mRNA levels begin to elevate 2 days later, at day 11. A significant increase in the mRNA levels for gonadotropin-releasing hormone (GnRH) receptors in the hypothalamus between days 5 and 7 was followed by a 3-fold decrease in GnRH mRNA levels in this brain region during the next 2 days. Starting from day 9, hypothalamic GnRH mRNA levels increased significantly and positively correlated with accelerated testicular growth. Triptorelin, an agonist of GnRH, at a dose that had no effect on testicular growth during "proportional" period, increased testis weights during the period of accelerated growth. The insensitivity of testicular growth to GnRH during "proportional" period was supported by inability of a 2.5-fold siRNA knockdown of GnRH expression in the hypothalamus of the 7-day-old animals to produce any effect on their testis weights. GnRH receptor blockade with cetrorelix was also without effect on testis weights during "proportional" period but the same doses of this GnRH antagonist significantly inhibited "accelerated" testicular growth. GnRH receptor mRNA levels in the pituitary as well as plasma LH concentrations were higher during "accelerated" period of testicular growth than during "proportional" period. In general, our data defined two distinct periods in rat testicular development that are primarily characterized by different responses to GnRH signaling.
We performed a targeted sequencing of 242 clinically important genes mostly associated with cardiovascular diseases in a representative population sample of 1,658 individuals from the Ivanovo region northeast of Moscow. Approximately 11% of 11,876 detected variants were not found in the Single Nucleotide Polymorphism Database (dbSNP) or reported earlier in the Russian population. Most novel variants were singletons and doubletons in our sample, and virtually no novel alleles presumably specific for the Russian population were able to reach the frequencies above 0.1-0.2%. The overwhelming majority (99.3%) of variants detected in this study in three or more copies were shared with other populations. We found two dominant and seven recessive known pathogenic variants with allele frequencies significantly increased compared to those in the gnomAD non-Finnish Europeans. Of the 242 targeted genes, 28 were in the list of 59 genes for which the American College of Medical Genetics and Genomics (ACMG) recommended the reporting of incidental findings. Based on the number of variants detected in the sequenced subset of ACMG59 genes, we approximated the prevalence of known pathogenic and novel or rare protein-truncating variants in the complete set of ACMG59 genes in the Ivanovo population at 1.4 and 2.8%, respectively. We analyzed the available clinical data and observed the incomplete penetrance of known pathogenic variants in the 28 ACMG59 genes: only 1 individual out of 12 with such variants had the phenotype most likely related to the variant. When known pathogenic and novel or rare protein-truncating variants were considered together, the overall rate of confirmed phenotypes was about 19%, with maximum in the subset of novel protein-truncating variants. We report three novel protein truncating variants in APOB and one in MYH7 observed in individuals with hypobetalipoproteinemia and hypertrophic cardiomyopathy, respectively. Our results provide a valuable reference for the clinical interpretation of gene sequencing in Russian and other populations.
Synthetic photonic lattices provide unique capabilities to realize theoretical concepts emerging in different fields of wave physics via the utilization of powerful photonic technologies.

Here we observe experimentally Anderson localization for optical pulses in time domain, using a photonic mesh lattice composed of coupled fiber loops. We introduce a random potential through programmed electro-optic pulse phase modulation, and identify the localization features associated with varying degree of disorder. Furthermore, we present a practical approach to control the band-gap width in photonic lattices by varying the coupling between the fiber loops.

We reveal that the strongest degree of localization is limited and increases in lattices with wider band-gaps. Importantly, this opens a possibility to enhance or reduce the effect of disorder and associated localization of optical pulses.
This paper presents a study of the pyrolysis products organic raw materials (bio-oil and sludge sediments of treatment facilities) by chromatographic methods.

A feature of the work is to optimize the sample preparation procedure by fractionating the pyrolysis products. Using the method of gel permeation chromatography, molecular weight distribution of pyrolysis products was assessed. Determination of the water content in these objects (by Karl Fischer titration) was used to assess the possibility of their direct analysis by gas chromatography. A sample of sludge pyrolysis and several fractions obtained from a bio-oil sample were analyzed. By the method of two-dimensional gas chromatography, where a selfdeveloped column based on an ionic liquid was used as the first measurement column, the pyrolysate of sludge sediments and the ether fraction of bio-oil were analyzed.

The obtained chromatograms and quantitative results are presented
We propose a new potent approach for studying nano/microscopic heterogeneities in ionic liquids exploiting stochastic librations of nitroxides and pulse EPR.
We present a seismic attenuation model for the crust beneath the Cenozoic basaltic field of Harrat Lunayyir (western Saudi Arabia), where a strong seismic swarm occurred in 2009.

The tomography inversion uses the envelope shape of the S wave seismograms from over 300 strong events (M < 3.5). The resulting attenuation structures appear to be consistent with the distribution of seismic velocities.

The obtained 3-D attenuation model distinguishes the low-attenuation zones down to 5 km depth corresponding to the rigid basaltic cover. At greater depths, we detect a high-attenuation anomaly coinciding with the main seismicity cluster. We propose that this zone corresponds to the upper part of the conduit area ascending from deeper magma sources. According to the distributions of local events, fluids and melts from this conduit appear to reach a depth of ∼2 km, but were not able to reach the surface and cause the eruption in 2009.
Skin fibroblasts from a patient with neurodevelopmental and speech delay, anxiety disorder, macrocephaly, microorchidism, multiple anomalies of internal organs and ring chromosome 13

were reprogrammed into induced pluripotent stem cells (iPSCs) to generate a clonal stem cell line IMGTi003-A (iTAF6-6). IMGTi003-A pluripotency was demonstrated by three germ layer differentiation capacity in vitro, and this cell line had a mosaic karyotype with 46,XY,r(13) as a predominant cell subpopulation

IMGTi003-A line is a good model for studying of the mitotic instability of the ring chromosome 13
Interregional integration is the most important property and form of manifestation of the unity of any economic space, in particular Russian. The study of this phenomenon is a significant area of research on the spatial development of the country. In the article the historical preconditions of the used approaches based on the theory of economic equilibrium have been studied and systematized.

We have described and analyzed various forms of spatial economic equilibrium which are adequate to the modern level of development and mathematical representation of economy. The development of the concept of economic equilibrium in economic and mathematical models is presented. It is shown that the simplicity of the mathematical structure of the OMIOM allows, using all the concepts of economic equilibrium, to analyze the features of interregional economic interactions and assess the degree of economic interdependence of the regions of Russia. The economic space in the OMIOM is presented discretely, in the context of macro-regions, which are federal districts or their large fragments, uniting several subjects of the federation. The economy of each macroregion is presented in the context of the aggregated sectors of production of goods and services.

For sectors with transportable products, interregional transport and economic ties are taken into account.
Background. Endosymbiotic bacteria of the genus Wolbachia are widespread in arthropods and often cause reproductive abnormalities in lepidopteran insects, including corn borers of the genus Ostrinia. Wolbachia-Ostrinia is a promising model for studies of parasite-host interactions yet parasite prevalence in natural insect host populations remains unknown. Materials and Methods. Molecular genetic screening and statistical analysis is applied to evaluate prevalence rates of Wolbachia in sympatric populations of two corn borer species. Individual genomic DNA samples were extracted from last instar larvae collected in nature from different forage plants. For each sample of DNA showing positive signal with insect-specific primers the detection is performed using three diagnostic loci of Wolbachia: 16SrRNA, gatB and fbpA. Results. Wolbachia-positive signal is obtained for 13.5% larvae of Ostrinia nubilalis (N = 141) and 31.9% larvae of Ostrinia scapulalis (N = 138). In different localities the Wolbachia prevalence ranged from 2.9% (N = 34) to 65.8% (N = 38). Significantly higher rates of Wolbachia prevalence in insects from mugwort and hemp (O. scapulalis) as compared to those from corn (O. nubilalis) are revealed in three out of four localities. Conclusions. Endosymbiotic bacteria of the genus Wolbachia are revealed in natural populations of corn borers for the first time for Eastern Europe. The prevalence rates can be high and this should be taken into consideration when reproductive isolation is examined in population of these hosts as well as establishment of laboratory cultures is performed.
Excitation-emission matrices of various plastic package samples were studied.

A tuneable 210-310 nm laser was used as an excitation source. The samples of polyethylene terephthalate, polypropylene, and high-density polyethylene of various colour and transparency showed multipeak wideband fluorescence spectra dependent on the excitation wavelength. Principal component analysis demonstrated that the excitation-emission matrices of most samples are well described by two principal components, individual for their types and colorant additives.

Despite complex structure of the excitation-emission matrices of different types of the plastic, appropriate linear combinations of the principal components allowed finding a characteristic component for each of them.
The solid-state photo-chemically induced dynamic nuclear polarization (photo-CIDNP) effect generates non-Boltzmann nuclear spin magnetization, referred to as hyperpolarization, allowing for high gain of sensitivity in nuclear magnetic resonance (NMR). Well known to occur in photosynthetic reaction centers, the effect was also observed in a light-oxygen-voltage (LOV) domain of the blue-light receptor phototropin, in which the functional cysteine was removed to prevent photo-chemical reactions with the cofactor, a flavin mononucleotide (FMN). Upon illumination, the FMN abstracts an electron from a tryptophan to form a transient spin-correlated radical pair (SCRP) generating the photo-CIDNP effect.

Here, we report on designed molecular spin-machines producing nuclear hyperpolarization upon illumination: a LOV domain of aureochrome1a from Phaeodactylum tricornutum, and a LOV domain named 4511 from Methylobacterium radiotolerans (Mr4511) which lacks an otherwise conserved tryptophan in its wild-type form. Insertion of the tryptophan at canonical and novel positions in Mr4511 yields photo-CIDNP effects observed by 15N and 1H liquid-state high-resolution NMR with a characteristic magnetic-field dependence indicating an involvement of anisotropic magnetic interactions and a slow-motion regime in the transient paramagnetic state.

The heuristic biomimetic design opens new categories of experiments to analyze and apply the photo-CIDNP effect.