Hengzongshu/ArticleAgent huggingface dataset:
The burden of malaria infection in the modern world remains significant. Specific changes in the relative proportions of malaria vector mosquitoes, Maculipennis Complex species, in the south of Western Siberia over the past 25 years of the 20th century have attracted wide attention as an indicator of their dynamic geographical distribution. In Eurasia, studies of fluctuations in the borders of areas occupied by sibling species of this complex, as well as their relative proportions in the areas where they are sympatric are epidemiologically important.

Species identity and chromosomal polymorphisms within each population were defined by cytogenetic analysis of polytene chromosomes of third- and fourth-instar larvae and adult females of Anopheles mosquitoes collected over the period from 1973 to 2012. A total of 37 Anopheles samples (3,757 specimens) from the Ukraine, European Russia and the Urals were studied. To identify An. messeae s.l. cryptic species A and B, polymerase chain reaction and restriction fragment length polymorphisms of the second internal transcribed spacer rRNA genes sequences (ITS2 PCR-RFLP) were used.

An. maculipennis s.s. is expanding to the northeast at a speed of approximately 30 km per year. In 2008 or 2009, this species appeared in the Southern Urals. The emergence of An. maculipennis in this region was accompanied by a decrease in the proportions of An. messeae A and An. beklemishevi and by an increase in the proportion of An. messeae B within An. messeae s.l. It is highly likely that the southwestern border of An. beklemishevi distribution area could shift in the same direction as expanding area of An. maculipennis. The geographical distribution of the Palaearctic mosquito species of the Maculipennis Complex is undergoing a gradual shift. Changes detected in the species distribution can be considered as a component of the biocenotic process triggered by global warming. Both the warming itself and consequent expansion of An. maculipennis s.s. to the northeast, followed by changes in the species composition of Anopheles as well as their relative proportions and fluctuations in the species areas, exacerbate the epidemiology of malaria infection in Eurasia.
Bacillus altitudinis strain KU-skv2(2) was isolated from a microbial mat on an anthropogenic pipe from Caldera Uzon. The sequenced and annotated genome is 3,739,340 bp in size and encodes 3,929 genes.
We study a noncommutative generalization of Jordan algebras called Jordan dialgebras. These are algebras that satisfy the identities ; they are related with Jordan algebras in the same way as Leibniz algebras are related to Lie algebras.

We present an analogue of the Tits–Kantor–Koecher (TKK) construction for Jordan dialgebras

that provides an embedding of such an algebra into Leibniz algebra.
Variability of the VRN1 promoter region of the unique collection of spring polyploid and wild diploid wheat species together with diploid goatgrasses (donor of B and D genomes of polyploid wheats) were investigated. Accessions of wild diploid (T. boeoticum, T. urartu) and tetraploid (T. araraticum, T. timopheevii) species were studied for the first time.

Sequence analysis indicated great variability in the region from -62 to -221 nucleotide positions of the VRN1 promoter region. Different indels were found within this region in spring wheats. It was shown that VRN1 promoter region of B and G genome can also contain damages such as the insertion of the transposable element. Some transcription factor recognition sites including hybrid C/G-box for TaFDL2 protein known as the VRN1 gene upregulator were predicted inside the variable region.

It was shown that deletions leading to promoter damage occurred in diploid and polyploid species independently. DNA transposon insertions first occurred in polyploid species. At the same time, the duplication of the promoter region was observed in A genomes of polyploid species. We can conclude that supposed molecular mechanism of the VRN1 gene activating in cultivated diploid wheat species T. monococcum is common also for wild T. boeoticum and was inherited by T. monococcum. The spring polyploids are not related in their origin to spring diploids. The spring T. urartu and goatgrass accessions have another mechanism of flowering activation that is not connected with indels in VRN1 promoter region. All obtained data may be useful for detailed insight into origin of spring wheat forms in evolution and domestication process.
This paper presents the results of an experimental study of the optical properties of highly resistive monocrystals of potassium titanyl phosphate (KTiOPO4, KTP) in the frequency range of 0.2–1 THz and the temperature range of (−192)–150 °C.

The dispersion of the refractive indices is approximated in the form of Sellmeier equations.

The results show that the temperature dependence of the Sellmeier coefficients for all three principal optical axes is close to linear and, most likely, does not experience an extremum in the vicinity of the activation temperatures of the cationic conductivity of the KTP crystal at (−73)–(−23) °C. Weak frequency dependence of an optical axis direction angle VZ in the range of 0.2–1 THz is confirmed. However, the change in VZ with temperature is three times higher than reported before.
Residual stresses are common in metal structures, essentially influencing their mechanical behaviour.

We consider a combined experimental/theoretical approach to residual stresses. The theoretical basis of analysis is provided by the recently developed F0-approach, operating with explicit relation between load-free and stress-free configurations. The titanium alloy Ti-6Al-4V is modelled with the multiplicative decomposition of the deformation gradient into the elastic and the plastic parts. Isotropic hyperelastic relations between stresses and elastic strains are assumed. The weak invariance of the material model allows for incorporation of residual stresses without additional numerical costs. In order to demonstrate the new experimental/theoretical approach to residual stresses, experimentally measured stresses are extrapolated from the surface inside the welded T-joint.

The robustness of the stress extrapolation procedure is confirmed on synthetic experimental data.
The synthesis of new allopolyploid cereal genotypes is an important task aimed at involving new genetic resources in breeding programs. Diploid species of the genera Triticum and Aegilops – bread wheat relatives – are an important source of agronomically valuable traits. A tetraploid synthetic with genomic formula DDAuAu was obtained by N.A. Navruzbekov through crossing Aegilops tauschii Coss. and Triticum urartu Thum. ex Gandil. The purpose of this work was to study the chromosomal composition and biological and commercially important traits of the tetraploid. Cytogenetic analysis using fluorescent in situ hybridization showed the presence of all chromosomes of the D genome in the chromosomal complement of the synthetic. By means of stepwise vernalization, the winter habit was established for the tetraploid synthetic with the optimum vernalization requirement of 45 days. Under greenhouse conditions, two groups of genotypes were found whose flowering dates differed by 6.5 days, which may indicate an allelism at the Vrn-3 locus. The coloring of various organs of the tetraploid plant, such as coleoptile, stem, anthers, and glumes of the spike, was revealed. The coloration of the aleurone layer of the grain may indicate that the donor species T. urartu is a carrier of the Ba gene that controls its blue color. A new morphotype of leaf pubescence was found. In terms of productivity, the tetraploid is comparable to bread wheat. Grains are characterized by a supersoft structure and high wet gluten content, from 39–45 to 65 %, in the field and greenhouse conditions, respectively. Thus, the tetraploid can be used to create new wheat genotypes as a source of untapped genetic diversity, as well as a new genetic model for studying the patterns of evolution of polyploid plants.
The Tunka-Grande scintillation array is part of the TAIGA Gamma Observatory. It is intended for investigation of energy spectrum and mass composition of primary cosmic rays in the energy range 10 PeV–10 EeV and the search for diffuse cosmic gamma rays. The TAIGA-HiSCORE Cherenkov array aims at observing gamma-rays with the energy from 1 TeV. TAIGA-Muon low-threshold scintillation detector array is a network of surface and underground detectors for registration charge particles of EAS. Currently, 3 clusters have been deployed. The first cluster is running in test mode. It is planed that in the future the total area of the TAIGA-Muon will be about 2000 sq. m. and it will search astrophysical gamma-rays in the energy range from 100 TeV together with the Tunka-Grande scintillation array and the Cherenkov experiments of the TAIGA Gamma Observatory. To evaluate the possibility of join operation Tunka-Grande, TAIGA-Muon and TAIGA-HiSCORE, a simulation was performed using the CORSIKA and Geant4 software packages. The status of model-based studies is presented and assessed the prospects for joint operation of the arrays.
High-energy photons and other particles carrying nonzero orbital angular momentum (OAM) emerge as a new tool in high-energy physics. Recently, it was suggested to generate high-energy photons with nonzero OAM (twisted photons) by the Compton backscattering of twisted optical photons on relativistic electron beams. Twisted electrons in the intermediate energy range have also been demonstrated experimentally; twisted protons and other particles can, in principle, be created in a similar way. Collisions of energetic twisted states can offer a new look at particle properties and interactions. A theoretical description of twisted particle scattering developed previously treated them as pure Bessel states and ran into difficulty when describing the OAM of the final twisted particle at nonzero scattering angles.

Here we develop further this formalism by incorporating two additional important features. First, we treat the initial OAM state as a wave packet of a finite transverse size rather than a pure Bessel state. This realistic assumption allows us to resolve the existing controversy between two theoretical analyses for nonforward scattering. Second, we describe the final twisted particle in terms of the orbital helicity: the OAM projection on its average direction of propagation rather than on the fixed reaction axis. Using this formalism, we determine to what extent the twisted state is transferred from the initial to final OAM particle in a generic scattering kinematics.

As a particular application, we prove that in the Compton backscattering the orbital helicity of the final photon stays close to the OAM projection of the initial photon.
Recent findings indicate that the microbiome may have significant impact on the development of lung cancer by its effects on inflammation, dysbiosis or genome damage. The aim of this study was to compare the sputum microbiome of lung cancer (LC) patients with the chromosomal aberration (CA) and micronuclei (MN) frequency in peripheral blood lymphocytes. In the study, the taxonomic composition of the sputum microbiome of 66 men with untreated LC were compared with 62 control subjects with respect to CA and MN frequency and centromere fluorescence in situ hybridisation analysis. Results showed a significant increase in CA (4.11 ± 2.48% versus 2.08 ± 1.18%) and MN (1.53 ± 0.67% versus 0.87 ± 0.49%) frequencies, respectively, in LC patients as compared to control subjects. The higher frequency of centromeric positive MN of LC patients was mainly due to aneuploidy. A significant increase in Streptococcus, Bacillus, Gemella and Haemophilus in LC patients was detected, in comparison to the control subjects while 18 bacterial genera were significantly reduced, which indicates a decrease in the beta diversity in the microbiome of LC patients. Although, the CA frequency in LC patients is significantly associated with an increased presence of the genera Bacteroides, Lachnoanaerobaculum, Porphyromonas, Mycoplasma and Fusobacterium in their sputum, and a decrease for the genus Granulicatella after application of false discovery rate correction, significance was not any more present. The decrease of MN frequency of LC patients is significantly associated with an increase in Megasphaera genera and Selenomonas bovis. In conclusion, a significant difference in beta diversity of microbiome between LC and control subjects and association between the sputum microbiome composition and genome damage of LC patients was detected, thus supporting previous studies suggesting an etiological connection between the airway microbiome and LC.
Purpose . To evaluate the clinical-ophthalmic effectiveness of using of autologous platelet-rich plasma as part of a comprehensive treatment regimen for uveitis associated with systemic diseases and accompanied by macular edema. Material and methods . The study included 120 people (176 eyes) from 18 to 50 years old with uveitis associated with systemic diseases, accompanied by macular edema: 46 men, 74 women. Patients were divided into 2 groups: the main group consisted of patients receiving antiinflammatory treatment and autologous platelet-rich plasma application; control group consisted of patients receiving anti-inflammatory treatment. All patients underwent a comprehensive ophthalmological examination. Results . It was found that autologous platelet-rich plasma application during anti-inflammatory treatment for patients with uveitis associated with systemic diseases and accompanied by macular edema improves best-corrected visual acuity, statistically significant decrease in retinal thickness in fovea and increase in retinal photosensitivity relative to the data obtained in the control group. Conclusion . The use of autologous platelet-rich plasma in combination with anti-inflammatory treatment decreases incidence of relapse of uveitis associated with systemic diseases, contributes to reducing macular edema and improving functional performance.
The transformation of the energy market and the development of its technologies radically change the industry and uncover new segments for competition. Scientific and technological progress is gradually changing the market structure and replacing petroleum products with other energy sources, creating new consumption sectors. However, the oil and gas industry still plays a major role in the energy and fuel balance of the world (almost 60% of global energy consumption is concentrated in the oil and gas sector). Due to the specifics of the petroleum sector, the companies tend to be large and have a significant direct and indirect influence on the oil industry as a whole. In this article, the authors of the study compared Russian and international companies in the oil and gas sector and identified the distinctive features of each group. To reveal the main factors influencing financial performance, we construct models of the dependence of net profit on various macroeconomic, microeconomic, institutional, and additional factors. The basic panel data model is tested, taking into account fixed and random individual effects. Results show that the profit of each major oil and gas company is affected by revenue, production costs, and tax deductions. The key interest rate set by the Central Bank of Russia is also important for the activities of oil and gas companies. A distinctive factor for petroleum corporations is the negative impact of financial leverage on the profits of domestic companies and the negative impact of investment in the environmental area for foreign companies. According to our forecasts, the total profit of the eight largest oil producers in Russia will decrease by 60% in 2020. Such forecasts are not very encouraging, but due to the current market situation, they are not surprising.
We introduce a number of random matrix models describing the Google matrix G of directed networks.

The properties of their spectra and eigenstates are analyzed by numerical matrix diagonalization.

We show that for certain models it is possible to have an algebraic decay of PageRank vector with the exponent similar to real directed networks. At the same time the spectrum has no spectral gap and a broad distribution of eigenvalues in the complex plain. The eigenstates of G are characterized by the Anderson transition from localized to delocalized states and a mobility edge curve in the complex plane of eigenvalues.
Despite significant achievements in the elucidation of the nature of protein-DNA contacts that control the specificity of nucleotide incision repair (NIR) by apurinic/apyrimidinic (AP) endonucleases, the question on how a given nucleotide is accommodated by the active site of the enzyme remains unanswered. Therefore, the main purpose of our study was to compare kinetics of conformational changes of three homologous APE1-like endonucleases (insect Drosophila melanogaster Rrp1, amphibian Xenopus laevis xAPE1, and fish Danio rerio zAPE1) during their interaction with various damaged DNA substrates, i.e., DNA containing an F-site (an uncleavable by DNA-glycosylases analog of an AP-site), 1, N 6 -ethenoadenosine (εA), 5,6-dihydrouridine (DHU), uridine (U), or the α-anomer of adenosine (αA). Pre-steady-state analysis of fluorescence time courses obtained for the interaction of the APE1-like enzymes with DNA substrates containing various lesions allowed us to outline a model of substrate recognition by this class of enzymes. It was found that the differences in rates of DNA substrates’ binding do not lead to significant differences in the cleavage efficiency of DNA containing a damaged base. The results suggest that the formation of enzyme–substrate complexes is not the key factor that limits enzyme turnover; the mechanisms of damage recognition and cleavage efficacy are related to fine conformational tuning inside the active site.
It is an almost consensus opinion that the major carcinogenic risk of tobacco smoke is in its direct mutagenic action on DNA of cancer-related genes. The key data supposedly linking smoke-induced mutations to lung cancer were obtained from the adduct spectrum of the p53 tumor suppressor gene.

Results of our analysis of p53 mutations compiled from the International Agency for Research on Cancer p53 database (April 1999 update) and from the literature point to a different causative link. Our new analytical tests focused on complementary base substitutions and showed that it is strand-specific repair of primary lesions and site-specific selection of the resultant mutations that determine the lung cancer-specific hot spots of G:C to T:A transversions along the p53 gene and also their increased abundance in lung tissues as compared with smoke-inaccessible tissues. However, on each of the two strands of p53 DNA, our tests revealed no significant difference between smokers and nonsmokers, either in the frequency of different types of mutations or in the frequency of their occurrence along the p53 gene. Moreover, in both smokers and nonsmokers, there was the same frequency of lung tumors with silent p53 mutations.

Accordingly, we offer here a selection-based explanation of why lung cancers with nonsilent p53 mutations are more common in smokers than in nonsmokers. We conclude that physiological stresses (not necessarily genotoxic) aggravated by smoking are the leading risk factor in the p53-associated etiology of lung cancer.
We have considered the features of the supersonic underexpanded flows formation under conditions of developed condensation, as well as measurements in such jets by electron-beam and molecular-beam methods.

A method of mass spectrometry of clustered flows during the ionization of gases in a jet before the formation of a molecular beam is proposed. The features of this method are illustrated.

It is shown that under the conditions of large clusters formation both the geometry and the structure of supersonic jets may change. It is determined that the use of a mass-analyzer for recording monomers and clusters in a molecular beam has a number of peculiarities caused by the molecular beam formation from a jet containing large clusters.
该摘要主要呈现染色体计数研究数据，未提供明确的相关研究背景部分。

所有材料均采用染色体计数（CHN）方法，在全球多个地区收集植物样本并进行染色体数目分析。

研究提供了大量植物的染色体数目数据，这些数据对理解植物遗传学和生物学特性具有重要意义。
A recently introduced electrostatic-based method to determine the pKa values of ionizable residues and fractions of ionized and tautomeric forms of histidine (His) and acid residues in proteins, at a given fixed pH, is applied here to the analysis of a His-rich protein, namely Loligo vulgaris (pdb id 1E1A), a 314-residue all-β protein.

The average tautomeric fractions for the imidazole ring of each of the six histidines in the sequence were computed using an approach that includes, but is not limited to, molecular dynamic simulations coupled with calculations of the ionization states for all 94 ionizable residues of protein 1E1A in water at pH 6.5 and 300 K. The electrostatic-calculated tautomeric fractions of the imidazole ring of His were compared with predictions obtained from an existent NMR-based methodology.

Our results indicate that: (i) the averaged electrostatic-based tautomeric predictions for the imidazole ring of all histidines of Loligo vulgaris are dominated by the Nε2-H rather than the Nδ1-H form, although such preferences from the NMR-based methodology are not so well defined; (ii) the computed average absolute difference between the electrostatic- and the NMR-based tautomeric predictions among all six histidines vary among 0% to 17%; (iii) for the His showing the largest fraction of the neutral form (81%), the absolute difference between the NMR- and electrostatic-based computed tautomeric predictions is only 3%; and (iv) the tautomeric predictions for the imidazole ring of His computed with the NMR-based methodology are stable within a certain, well-defined, range of variations of a tautomer-related parameter.
The article precedes the republishing of the poem of the Harbin poet Alexei Achair (Gryzov; 1896–1960) “Cossacks”, completed by the author at the end of 1927. It was published twice in 1929 in hard-to-reach publications for the modern reader: in two issues of the collection “Free Siberia” (Prague) and in the newspaper “Russian Word” (Harbin). The forgotten poem deserves attention as a case of early imitation of Marina Tsvetaeva’s poems, primarily the Pied Piper, and also as a detailed essay reflecting the regional mentality of the “storm and onslaught” period of the “Young Churaevka” circle. In addition, this is the largest in volume and the most significant in scale work of Air, the only poem published during his lifetime. Achair reproduced the characteristic techniques of Tsvetaeva’s “big form” poetics and tried to put them at the service of the propaganda of Siberian regionalism. Along with Tsvetaeva, who determined the artistic structure of the poem, echoes of Soviet poetry (Khlebnikov, Mayakovsky, Selvinsky) are also heard, which makes the overall impression of the poem mosaic.