These tophi occur in 30% of those who are untreated for five years, often in the helix of the ear, over the olecranon processes, or on the Achilles tendons.
== Prognoza ==Akutni napad protina, če se ga ne zdravi, ponavadi izzveni v petih do sedmih dneh; 60% ljudi pa v roku enega leta doživi ponoven napad.