A recipient of a star on the Hollywood Walk of Fame, Barrymore appeared on the cover of the 2007 "People" magazine's 100 Most Beautiful issue.
Po težavnem otrošvu, ki sta ga zaznamovala odvisnost od drog in alkohola ter dve rehabilitaciji, je Drew Barrymore leta 1990 napisala avtobiografično knjigo z naslovom "Little Girl Lost".