==Commercial performance==On October 25, 2003, "Me Against the Music" debuted at number 50 on the "Billboard" Hot 100.
V pesmi Britney Spears in Madonna prepevata o užitkih ob sproščanju na plesišču, kar opišeta z besedami: »Sem ob mikrofonu / Poskušam prevzeti glasbo / Je kot tekmovanje« (»I'm up against the speaker / Trying to take on the music / It's like a competition«).