Three years later, he received the commission for the altarpiece of the church of the Misericordia in San Sepolcro (including the "Madonna della Misericordia"), which he was to complete only in the early 1460s.
Klasicizem na Masacciovih freskah in njihova mogočna sporočila v kraju "Santa Maria del Carmine" je bil zanj prav tako pomemben vir navdiha.