The title is a reference to the "Mona Lisa", the famous painting by Leonardo da Vinci, and the song of the same name, originally performed by Nat King Cole, which was covered by Seal for the movie.
Nasmeh Mone Lise je dramski film iz leta 2003, ki sta ga producirali podjetji Revolution Studios in Red Om Films Productions, režiral ga je Mike Newell, scenarij zanj sta napisala Lawrence Konner in Mark Rosenthal, v njem pa so zaigrale Julia Roberts, Kirsten Dunst, Maggie Gyllenhaal in Julia Stiles.