The first version of the DSM (DSM-I, 1952) contained "depressive reaction" and the DSM-II (1968) "depressive neurosis", defined as an excessive reaction to internal conflict or an identifiable event, and also included a depressive type of manic-depressive psychosis within Major affective disorders.
Meyer put forward a mixed social and biological framework emphasizing "reactions" in the context of an individual's life, and argued that the term "depression" should be used instead of "melancholia".