The principal settlements of the province were Castra Vetera and Colonia Ulpia Traiana (both near Xanten), Coriovallum (Heerlen), Albaniana (Alphen aan den Rijn), Lugdunum Batavorum (Katwijk), Forum Hadriani (Voorburg), Ulpia Noviomagus Batavorum (Nijmegen), Traiectum (Utrecht), Atuatuca Tungrorum (Tongeren), Bona (Bonn), and Colonia Agrippinensis (Cologne), the capital of Germania Inferior.
Glavno mesto province je bila Siscia, sedanji Sisak.