On September 14, 2003, Spears played a surprise concert at Rain Nightclub in the Palms Casino Resort, and performed "Me Against the Music", "Breathe on Me" and a medley of "...Baby One More Time" and "I'm a Slave 4 U".
Britney Spears je pesem »Me Against the Music« prvič izvedla na otvoritvi športne prireditve NFL 4. septembra 2003 v nakupovalnem centru National Mall.