Messing turned down a starring role in another television sitcom to appear in Donald Margulies's two-character play "Collected Stories", which opened at the Off Broadway Manhattan Theater Club.
Kot dekle Jerryja Seinfelda se je pojavila v televizijski seriji "Seinfeld" in sicer v epizodah: »The Wait Out« (1996) in »The Yada Yada« (1997).