Guillaume Dufay was a transitional figure in this regard; he wrote one of the last important motets in the medieval, isorhythmic style, "Nuper rosarum flores" (1436), written to commemorate the completion of Filippo Brunelleschi's dome in the Cathedral of Florence.
Medtem ko je prerasel srednjeveški izoritmični motet, so renesančni skladatelji moteta običajno opustili rabo ponavljajoče figure, znane kot cantus firmus.