On the east there is at first a succession of small rivers which flow into the Adriatic, from which the highest points of the chain are some 20 km distant, such as the Potenza, Chienti, Tenna, Tronto, Tordino, Vomano and others.
Največja reka na zahodu je Nera, s svojimi pritoki Velino, Salto in Aniene, ki sta spadajo v porečje Tibere.