A study conducted by E-Poll Market Research showed that Witherspoon was the most likable female celebrity of 2007.
Leta 2006 je revija "Star" objavila zgodbo, ki je trdila, da je Reese Witherspoon tretjič noseča, zaradi česar je Witherspoonova tožila revijino matično družbo, American Media Inc, zaradi vdora v zasebnost.