The illness may have been triggered by a traumatic childbirth, the death of her father three weeks earlier, stress from in vitro fertilization, a miscarriage and a family history of depression, as well as the hormones and life changes which were brought on by childbirth.
Od 19. aprila 1997 do 9. aprila 1999 je bila poročena s tenisačem Andrejem Agassijem; par sta postala leta 1993.