When the film remake "The Women" was in pre-production in 2006, Thurman was cast as Crystal Allen, alongside Annette Bening, Julia Roberts, Meg Ryan, Sandra Bullock, Ashley Judd, Lisa Kudrow and Anne Hathaway, being directed by James L. Brooks, but the director was changed and Thurman was no longer part of the cast.
7. februarja 2006 jo je Ordre des Arts et des Lettres imenoval za viteza za njen prispevek k umetnosti in literaturi.