The plot follows Will Turner (Orlando Bloom), Elizabeth Swann (Keira Knightley), Hector Barbossa (Geoffrey Rush), and the crew of the "Black Pearl" rescuing Captain Jack Sparrow (Johnny Depp) from Davy Jones' Locker, and then preparing to fight the East India Trading Company, led by Cutler Beckett (Tom Hollander) and Davy Jones (Bill Nighy), who plan to extinguish piracy forever.
Pirati s Karibov: Na robu sveta (v izvirniku "Pirates of the Caribbean: At World's End") je pustolovski film iz leta 2007, tretji film iz filmske serije "Pirati s Karibov".