Modification of the 7-ACA side chains resulted in the development of useful antibiotic agents, and the first agent, cefalotin (cephalothin), was launched by Eli Lilly and Company in 1964.
== Zgodovina ==Cefalosporinske spojine je prvi osamil italijanski znanstvenik Giuseppe Brotzu leta 1948, in sicer iz glive "Cephalosporium acremonium" .