The guidelines further note that antidepressant treatment should be continued for at least six months to reduce the risk of relapse, and that SSRIs are better tolerated than tricyclic antidepressants.
The guidelines recommend that antidepressants treatment in combination with psychosocial interventions should be considered for::* People with a past history of moderate or severe depression:* Those with mild depression that has been present for a long period:* As a second line treatment for mild depression that persists after other interventions:* As a first line treatment for moderate or severe depression.