Innovating with the courage and felicity of genius, he had for a time an overwhelming influence on his contemporaries and immediate successors in the Venetian school, including Titian, Sebastiano del Piombo, Palma il Vecchio, il Cariani, Giulio Campagnola (and his brother), and even on his already eminent master, Giovanni Bellini.
Giorgione je uvedel tudi nov nabor predmetov.