In September 2009, Breslin filmed in Des Moines, Iowa, playing the title character in the film "Janie Jones": a 13-year-old girl who is abandoned by her former-groupie mother (Elisabeth Shue), and informs Ethan Brand (Alessandro Nivola), a fading rock star, that she is his daughter.
Februarja 2010 je Abigail Breslin prvič zaigrala na Broadwayju; v gledališki igri "The Miracle Worker" je namreč zaigrala Helen Keller.