After ending southbound at Interstate 55, the highway continues as U.S. Route 60, which meets U.S. Route 67 at Poplar Bluff, Missouri, and from there U.S. Route 67 goes south to Little Rock, Arkansas.
== Маршрут магистрали ==Южный конец автомагистрали Interstate 57 располагается в городе Майнер штата Миссури, на пересечении с Interstate 55 и US 60.