According to data from 2005, the ethnic make-up of Isfana and the six subordinated villages is as follows: 50.2 percent are Kyrgyz, 48.6 percent are Uzbek, 0.3 percent are Tatar, 0.3 percent are Tajik, and the rest are representatives of various other ethnic groups.
По данным 2005 года национальный состав города и шести подчиненных сёл таков: 50,2% киргизы, 48,6% узбеки, 0,3% татары, 0,3% таджики, остальное — представители других национальностей.