Manuel Roxas studied college in University of Manila, and law at the University of the Philippines College of Law, where he was a member of the college's first ever graduating class in 1913.
Nagtapos siya ng abogasya sa Unibersidad ng Pilipinas (University of the Philippines)noong 1912 at naging topnatcher sa Bar. Nag-umpisa siya sa pulitika bilang piskal panlalawigan.