Active colonization began to happen in the late 18th century when was founded Ekaterinoslav (now Dnepropetrovsk), and received a new impetus in the mid 19th century. It was connected with the fact that the territory began to be actively developed rich deposits of minerals that are used in ferrous and nonferrous metallurgy.
Section dahil ito kinuha lugar sa ilog. Aktibong pananakop nagsimulang mangyari sa huli 18th siglo kapag ay itinatag Ekaterinoslav (ngayon Dnepropetrovsk), at nakatanggap ng isang bagong puwersa sa kalagitnaan ng ika-19 siglo.