In this work he had attacked the commentary written by Theon of Alexandria and, in so doing, he upset Cardinal Johannes Bessarion, papal legate to the Holy Roman Empire, who was a great admirer of Theon . Cardinal Bessarion was a scholar and native Greek speaker who had a mission to promote classical Greek works in Europe.
Sa ganitong trabaho niya attacked ang puna sa pamamagitan ng nakasulat na Theon ng Alexandria at, sa gayon paggawa, siya mapataob Cardinal Johannes Bessarion, papa sugo sa Banal na Roman Empire, na noon ay isang magandang admirer ng Theon. Cardinal Bessarion ay isang iskolar at katutubong Greek speaker na nagkaroon ng isang misyon upang itaguyod klasiko Greek gumagana sa Europa.