Huling Halik is a passionate gay drama about the end of a love affair between two college freshmen set during the colourful Flower Festival in Baguio. JM (Kenjie Garcia) is a troubled student obsessed with his schoolmate Ili (Joeffrey Javier).
After 23 years, lumaki si Isabel bilang isang modelo ng lingerie brand na ang pangalan ay Madame X. Jowa niya si Alex (Gary Estrada) na anak naman ng don. Nagbakasyon sila sa hacienda at nakilala niya ang dalawa pa nitong kapatid na sina Arnulfo(Alvin Anson) at Adrian (James Harper).