From 1947 Householder spent eight years working on mathematical biology as a member of the Committee for Mathematical Biology at the University of Chicago. John Hearon, after retiring from the National Institutes of Health, wrote of Householder's work over this period:
Mula 1947-ari ng bahay na ginugol sa walong taon ang paggawa sa matematika biology bilang isang miyembro ng Committee para sa matematika Biyolohiya sa University of Chicago. John Hearon, matapos mahihiyain mula sa National Institutes of Health, wrote of-ari ng bahay ng trabaho sa loob ng panahong ito: