It was not to be, however, and by March 1853 it was clear that he was sinking fast. Doppler's wife, who had given him staunch support throughout their marriage, had remained in Vienna with their three sons and two daughters awaiting his return but, on realising that his end was near, she made the journey to Venice and was with Doppler when he died.
Ito ay hindi na, gayunpaman, at sa pamamagitan ng Marso 1853, ito ay malinaw na siya ay mabilis na paglubog. Doppler ng asawa, na ibinigay sa kanya pigilin ang pagdaloy ng dugo ng suporta sa kabuuan ng kanilang kasal, nagkaroon na naiiwan sa Vienna sa kanilang tatlong anak at dalawang anak naghihintay sa kanyang bumalik ngunit, sa realising na ang kanyang katapusan ay malapit na, siya na ginawa ang paglalakbay sa Venice at sa mga Doppler kapag siya namatay .