Ako je heterogenost varijanci i/ili devijacija od normalne razdiobe prevelika i ne može se ispraviti transformacijom, treba razmotriti mogućnost analize metodama kao što su Bonferroni-Welchov t-test, Jonckheere-Terpstrin ‚step-down’ test i Bonferronijev test jednakovrijednosti medijana.
OECD (1998) Harmonized Integrated Hazard Classification System for Human Health and Environmental Effects of Chemical Substances, as endorsed by the 28th Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, November 1998 (http://www.oecd.org/ehs/Class/HCL6.htm).