Buggy python submission (verdict: Time Limit Exceeded):
from bisect import bisect_left, bisect_right

N = int(input())

S = list(input())

Q = int(input())

memo = [[]*N for _ in range(26)]

for key,val in enumerate(S):
    ch = ord(val)-97
    memo[ch].append(key)

for q in range(Q):
    query = list(input().split())
    if query[0] == '1':
        i, x = int(query[1])-1, query[2]
        now = S[i]
        now_cn = ord(now)-97
        nex_ch = ord(x)-97
        if nex_ch == x:
            continue
        memo[now_cn].remove(i)
        next_i = bisect_left(memo[nex_ch], i)
        memo[nex_ch].insert(next_i, i)
        S[i] = x
    else:
        start, end = int(query[1])-1, int(query[2])-1
        tmp_cout = 0
        for alf_array in memo:
            if len(alf_array) == 0:
                continue
            ss = bisect_left(alf_array, start)
            gg = bisect_right(alf_array, end)
            if gg- ss > 0:
                tmp_cout += 1
        print(tmp_cout)


Fixed submission:
from bisect import bisect_left, bisect_right

N = int(input())
S = list(input())
Q = int(input())

D = {chr(ord('a') + i): [] for i in range(26)}
for i, s in enumerate(S):
    D[s].append(i)

for q in range(Q):
    query = list(input().split())
    if query[0] == '1':
        i, x = int(query[1]), query[2]
        i -= 1
        s = S[i]
        if s == x:
            continue

        D[s].remove(i)
        next_i = bisect_left(D[x], i)
        D[x].insert(next_i, i)
        S[i] = x

    if query[0] == '2':
        l, r = int(query[1]), int(query[2])
        l, r = l - 1, r - 1
        ans = 0
        for i in range(26):
            s = chr(ord('a') + i)

            li = bisect_left(D[s], l)
            ri = bisect_right(D[s], r)

            if ri - li > 0:
                ans += 1

        print(ans)

Buggy python submission (verdict: Runtime Error):
N = int(input())
S = list(input())
Q = int(input())

D = {chr(ord('a') + i): [] for i in range(26)}
for i, s in enumerate(S):
    D[s].append(i)

for q in range(Q):
    query = list(input().split())
    if query[0] == '1':
        i, x = int(query[1]), query[2]
        i -= 1
        s = S[i]
        if s == x:
            continue

        D[s].remove(i)
        next_i = bisect_left(D[x], i)
        D[x].insert(next_i, i)
        S[i] = x

    if query[0] == '2':
        l, r = int(query[1]), int(query[2])
        l, r = l - 1, r - 1
        ans = 0
        for i in range(26):
            s = chr(ord('a') + i)

            li = bisect_left(D[s], l)
            ri = bisect_right(D[s], r)

            if ri - li > 0:
                ans += 1

        print(ans)

Fixed submission:
from bisect import bisect_left, bisect_right

N = int(input())
S = list(input())
Q = int(input())

D = {chr(ord('a') + i): [] for i in range(26)}
for i, s in enumerate(S):
    D[s].append(i)

for q in range(Q):
    query = list(input().split())
    if query[0] == '1':
        i, x = int(query[1]), query[2]
        i -= 1
        s = S[i]
        if s == x:
            continue

        D[s].remove(i)
        next_i = bisect_left(D[x], i)
        D[x].insert(next_i, i)
        S[i] = x

    if query[0] == '2':
        l, r = int(query[1]), int(query[2])
        l, r = l - 1, r - 1
        ans = 0
        for i in range(26):
            s = chr(ord('a') + i)

            li = bisect_left(D[s], l)
            ri = bisect_right(D[s], r)

            if ri - li > 0:
                ans += 1

        print(ans)