由美国基督教贵格会、American Presbyterian Church, South (美南长老会)、American Presbyterian Church, North (美北长老会)、Methodist Episcopal Church (美以美会)、Methodist Episcopal Church, South (监理会)、Disciples of Christ (基督会)和浸礼会等差会派代表组成。美国传教士沙德纳为首任校长，借用进德女校为院址。1921年10月迁入大锏银巷新建校舍。抗日战