From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for CD40 ligand
Date: 3 Jan 93 22:15:23 GMT
Distribution: bionet
Checksum: 36065 4

LOCUS       HUMCD40      1803 bp ss-RNA             PRI       23-DEC-1992
DEFINITION  H.sapiens mRNA for CD40 ligand
ACCESSION   X67878
KEYWORDS    glycoprotein.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Spriggs,M.K., Armitage,R.J., Strockbine,L., Clifford,K.N.,
            Macduff,B.M., Sato,T.A., Maliszewski,C.R. and Fanslow,W.C.
  TITLE     Recombinant human CD40 ligand stimulates B cell proliferation and
            immunoglobulin E secretion
  JOURNAL   J. Exp. Med. 176, 1543-1550 (1992)
  STANDARD  full automatic
COMMENT     *source: cell_type=peripheral blood T-cell;
               From EMBL    entry HSCD40;  dated 14-DEC-1992.
FEATURES             Location/Qualifiers
     sig_peptide     112..183
                     /product="CD40 ligand"
                     /note="NH2 signal /anchor"
     CDS             46..831
                     /product="CD40 ligand"
                     /codon_start=1
                     /translation="MIETYNQTSPRSAATGLPISMKIFMYLLTVFLITQMIGSALFAV
                     YLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLNCEEIKSQFEGFVKDIMLNK
                     EETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQ
                     LTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPC
                     GQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL"
BASE COUNT      510 a    456 c    344 g    493 t
ORIGIN      
        1 tgccaccttc tctgccagaa gataccattt caactttaac acagcatgat cgaaacatac
       61 aaccaaactt ctccccgatc tgcggccact ggactgccca tcagcatgaa aatttttatg
      121 tatttactta ctgtttttct tatcacccag atgattgggt cagcactttt tgctgtgtat
      181 cttcatagaa ggttggacaa gatagaagat gaaaggaatc ttcatgaaga ttttgtattc
      241 atgaaaacga tacagagatg caacacagga gaaagatcct tatccttact gaactgtgag
      301 gagattaaaa gccagtttga aggctttgtg aaggatataa tgttaaacaa agaggagacg
      361 aagaaagaaa acagctttga aatgcaaaaa ggtgatcaga atcctcaaat tgcggcacat
      421 gtcataagtg aggccagcag taaaacaaca tctgtgttac agtgggctga aaaaggatac
      481 tacaccatga gcaacaactt ggtaaccctg gaaaatggga aacagctgac cgttaaaaga
      541 caaggactct attatatcta tgcccaagtc accttctgtt ccaatcggga agcttcgagt
      601 caagctccat ttatagccag cctctgccta aagtcccccg gtagattcga gagaatctta
      661 ctcagagctg caaataccca cagttccgcc aaaccttgcg ggcaacaatc cattcacttg
      721 ggaggagtat ttgaattgca accaggtgct tcggtgtttg tcaatgtgac tgatccaagc
      781 caagtgagcc atggcactgg cttcacgtcc tttggcttac tcaaactctg aacagtgtca
      841 ccttgcaggc tgtggtggag ctgacgctgg gagtcttcat aatacagcac agcggttaag
      901 cccaccccct gttaactgcc tatttataac cctaggatcc tccttatgga gaactattta
      961 ttatacactc caaggcatgt agaactgtaa taagtgaatt acaggtcaca tgaaaccaaa
     1021 acgggccctg ctccataaga gcttatatat ctgaagcagc aaccccactg atgcagacat
     1081 ccagagagtc ctatgaaaag acaaggccat tatgcacagg ttgaattctg agtaaacagc
     1141 agataacttg ccaagttcag ttttgtttct ttgcgtgcag tgtctttcca tggataatgc
     1201 atttgattta tcagtgaaga tgcagaaggg aaatggggag cctcagctca cattcagtta
     1261 tggttgactc tgggttccta tggccttgtt ggagggggcc aggctctaga acgtctaaca
     1321 cagtggagaa ccgaaacccc cccccccccc ccgccaccct ctcggacagt tattcattct
     1381 ctttcaatct ctctctctcc atctctctct ttcagtctct ctctctcaac ctctttcttc
     1441 caatctctct ttctcaatct ctctgtttcc ctttgtcagt ctcttccctc ccccagtctc
     1501 tcttctcaat ccccctttct aacacacaca cacacacaca cacacacaca cacacacaca
     1561 cacacacaca cagagtcagg ccgttgctag tcagttctct tctttccacc ctgtccctat
     1621 ctctaccact atagatgagg gtgaggagta gggagtgcag ccctgagcct gcccactcct
     1681 cattacgaaa tgactgtatt taaaggaaat ctattgtatc tacctgcagt ctccattgtt
     1741 tccagagtga acttgtaatt atcttgttat ttattttttg aataataaag acctcttaac
     1801 att
//