From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human cytochrome P4502C18 (CYP2C18) mRNA, clone 29c.
Date: 5 Sep 92 10:01:17 GMT
Distribution: bionet
Checksum: 12124     5

LOCUS       HUMCYP2C18   1995 bp ss-mRNA            PRI       05-SEP-1992
DEFINITION  Human cytochrome P4502C18 (CYP2C18) mRNA, clone 29c.
ACCESSION   M61856 J05326
KEYWORDS    cytochrome P-450; cytochrome P-450 2C18.
SOURCE      Human, cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1995)
  AUTHORS   Goldstein,J.A., Raucy,J.L., Blaisdell,J.A., Faletto,M.B. and
            Romkes,M.
  TITLE     Cloning and expression of complementary DNAs for multiple members
            of the human cytochrome P450IIC subfamily
  JOURNAL   Biochemistry 30, 3247-3255 (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     CDS             200..1672
                     /product="cytochrome"
                     /codon_start=1
                     /translation="MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQ
                     LDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPV
                     AEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTN
                     ASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNN
                     FPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKH
                     NQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRN
                     RSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLT
                     SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLT
                     TILQNFNLKSQVDPKDIDITPIANAFGRVPPLYQLCFIPV"
     old_sequence    replace(204..205,"ta")
                     /citation=[1]
     old_sequence    replace(1413,"c")
                     /citation=[1]
                     /note="addition of c"
     old_sequence    replace(1433,"g")
                     /citation=[1]
                     /note="deletion of g"
     polyA_site      1995
BASE COUNT      556 a    455 c    438 g    546 t
ORIGIN
        1 ggcaccggaa agaacaagaa aaaagaacac cttattttta tcttcttcag tgagccaatg
       61 ttcattcaaa agagagatta aagtgctttt tgctgactag tcacagtcag agtcagaatc
      121 acaggtggat tagtagggag tgttataaaa gccttgaagt gaaagcccgc agttgtctta
      181 ctaagaagag aagccttcaa tggatccagc tgtggctctg gtgctctgtc tctcctgttt
      241 gtttctcctt tcactctgga ggcagagctc tggaagaggg aggctcccgt ctggccccac
      301 tcctctcccg attattggaa atatcctgca gttagatgtt aaggacatga gcaaatcctt
      361 aaccaatttc tcaaaagtct atggccctgt gttcactgtg tattttggcc tgaagcccat
      421 tgtggtgttg catggatatg aagcagtgaa ggaggccctg attgatcatg gagaggagtt
      481 ttctggaaga ggaagttttc cagtggctga aaaagttaac aaaggacttg gaatcctttt
      541 cagcaatgga aagagatgga aggagatccg gcgtttctgc ctcatgactc tgcggaattt
      601 tgggatgggg aagaggagca tcgaggaccg tgttcaagag gaagcccgct gccttgtgga
      661 ggagttgaga aaaaccaatg cctcaccctg tgatcccact ttcatcctgg gctgtgctcc
      721 ctgcaatgtg atctgctctg ttattttcca tgatcgattt gattataaag atcagaggtt
      781 tcttaacttg atggaaaaat tcaatgaaaa cctcaggatt ctgagctctc catggatcca
      841 ggtctgcaat aatttccctg ctctcatcga ttatctccca ggaagtcata ataaaatagc
      901 tgaaaatttt gcttacatta aaagttatgt attggagaga ataaaagaac atcaagaatc
      961 cctggacatg aacagtgctc gggactttat tgattgtttc ctgatcaaaa tggaacagga
     1021 aaagcacaat caacagtctg aatttactgt tgaaagcttg atagccactg taactgatat
     1081 gtttggggct ggaacagaga caacgagcac cactctgaga tatggactcc tgctcctgct
     1141 gaagtaccca gaggtcacag ctaaagtcca ggaagagatt gaatgtgtag ttggcagaaa
     1201 ccggagcccc tgtatgcagg acaggagtca catgccctac acagatgctg tggtgcacga
     1261 gatccagaga tacattgacc tcctccccac caacctgccc catgcagtga cctgtgatgt
     1321 taaattcaaa aactacctca tccccaaggg cacgaccata ataacatccc tgacttctgt
     1381 gctgcacaat gacaaagaat tccccaaccc agagatgttt gaccctggcc actttctgga
     1441 taagagtggc aactttaaga aaagtgacta cttcatgcct ttctcagcag gaaaacggat
     1501 gtgtatggga gagggcctgg cccgcatgga gctgttttta ttcctgacca ccattttgca
     1561 gaactttaac ctgaaatctc aggttgaccc aaaggatatt gacatcaccc ccattgccaa
     1621 tgcatttggt cgtgtgccac ccttgtacca gctctgcttc attcctgtct gaagaagggc
     1681 agatagtttg gctgctcctg tgctgtcacc tgcaattctc ccttatcagg gccattagcc
     1741 tctcccttct ctctgtgagg gatattttct ctgacttgtc aatccacatc ttcccattcc
     1801 ctcaagatcc aatgaacatc caacctccat taaagagagt ttcttgggtc acttcctaaa
     1861 tatatctgct attctccata ctctgtatca cttgtattga ccaccacata tgctaatacc
     1921 tatctactgc tgagttgtca gtatgttatc actagaaaac aaagaaaaat gattaataaa
     1981 tgacaattca gagcc
//