From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA titin (subclone C26/C18)
Date: 24 Jul 92 10:07:39 GMT
Distribution: bionet
Checksum: 35291     7

LOCUS       HUMTITINC2   3300 bp ss-RNA             PRI       24-JUL-1992
DEFINITION  H.sapiens mRNA titin (subclone C26/C18)
ACCESSION   X64698
KEYWORDS    fibronectin type-III repeat; immunoglobulin-C2; myosin-binding;
            titin gene.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3300)
  AUTHORS   Labeit,S., Gautel,M., Lakey,A. and Trinick,J.
  TITLE     Towards a molecular understanding of titin
  JOURNAL   EMBO J. 11, 1711-1716 (1992)
  STANDARD  full automatic
COMMENT     *source: clone_library=#936208; *source: isolate=CH11
            immuno-positives; *source: chromosome=2; *source: sub_clone=
            C26/C18;
            From EMBL    entry HSTITINC2;  dated 12-MAY-1992.
FEATURES             Location/Qualifiers
     CDS             <1..>3300
                     /product="titin"
                     /codon_start=1
                     /translation="TLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRV
                     TRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLT
                     WTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAI
                     NLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVE
                     KRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIIC
                     KDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQ
                     ITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVS
                     AEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYI
                     FRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGS
                     EITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSE
                     ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHIDGGLEITGYVVEHQKVGDE
                     AWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPD
                     FELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI
                     IPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTARPSPQLRPTDITKDSVTLHWDLP
                     LIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGI
                     GEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKG
                     SDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPEL
                     DLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTIL
                     NINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWD
                     PPENDGGVPISN"
BASE COUNT     1053 a    721 c    768 g    758 t
ORIGIN
        1 accttaaagt gggctcctcc aaaggatgat ggaggttctg aaatcaccaa ctatatccta
       61 gagaagaggg attctgtgaa caacaagtgg gtgacgtgcg cctcagctgt ccagaaaacc
      121 acctttagag taaccagact tcatgagggc atggaatata ccttcagggt cagtgccgaa
      181 aataaatatg gtgtagggga aggcctgaaa tcggagccaa ttgttgcgag acatccattt
      241 gatgtgcctg atgctccccc acctcccaat attgtggatg tcagacacga ttcagtatct
      301 ctaacttgga ctgaccccaa gaaaactggt ggttctccaa ttacagggta tcatctcgag
      361 ttcaaggaaa gaaacagcct tttgtggaag agagctaaca agactccgat aaggatgaga
      421 gactttaaag tgacaggatt aactgaaggt cttgaatatg aattccgagt tatggcaatc
      481 aatttagcag gtgtgggcaa gccaagccta ccatcagagc ctgttgtggc actggaccca
      541 attgatcctc ctggaaaacc tgaggttatt aacataacaa ggaattcagt gactctcatt
      601 tggactgaac ctaaatatga cggtggtcat aagttaactg gatatatagt ggagaagcga
      661 gatctacctt cgaagtcttg gatgaaagcc aaccatgtta atgtcccaga atgtgccttt
      721 actgtaactg accttgttga gggtggaaaa tatgaattca gaattagagc aaagaataca
      781 gcaggtgcta tcagtgctcc atcagaaagt acagaaacca ttatttgcaa ggatgaatac
      841 gaggcaccaa caattgtcct tgatcccaca ataaaagatg ggctaacaat taaagcaggg
      901 gataccattg ttttgaatgc cattagcatt cttggcaaac cccttccaaa atcaagttgg
      961 tccaaggcag gaaaagacat tagaccatca gatatcactc agataacttc aaccccaaca
     1021 tcttccatgc ttactatcaa gtatgccact agaaaagatg cgggtgaata taccatcact
     1081 gctaccaatc cttttggcac gaaggtggaa catgtgaagg taacagtcct tgatgtacct
     1141 ggtcccccag gtcctgttga aatcagtaat gtttctgctg aaaaagcaac acttacatgg
     1201 acacctccct tggaagatgg cggctcacca attaagtcct atatacttga aaagagagaa
     1261 accagccgac ttttgtggac agtggtttct gaagatattc agtcttgcag gcatgtggca
     1321 accaaactta tccaaggaaa tgagtacatc ttccgggtct cagctgtaaa ccactatggc
     1381 aaaggagaac ctgtacagtc tgaacctgtc aaaatggtag acagatttgg tccccctggc
     1441 cctcctgaaa aaccagaggt atcaaatgtc actaagaaca ctgccactgt cagctggaaa
     1501 aggccagtgg atgatggtgg cagcgaaatt acaggatatc atgtagaaag gagagaaaag
     1561 aaaagcctgc gatgggtgag agcaataaaa acaccagttt ccgatctcag gtgcaaagta
     1621 acaggactgc aagaaggaag cacctacgaa ttccgtgtca gtgcagaaaa cagagcagga
     1681 attggtccac ccagtgaggc ttcagattct gttctgatga aagatgcagc atatcctcca
     1741 ggaccacctt caaatccgca tgtcactgat actaccaaga aatctgcttc tttggcatgg
     1801 ggcaagcctc atattgatgg tggacttgaa atcactggct atgtcgtgga gcatcaaaaa
     1861 gtaggagacg aggcctggat aaaagatacc acaggaaccg ccctcagaat cactcagttc
     1921 gttgttcctg atcttcagac taaagaaaaa tacaacttca gaatcagtgc catcaacgat
     1981 gcaggtgttg gggagccagc ggtgattcca gatgttgaaa tcgtagaacg ggagatggct
     2041 cctgattttg aactagatgc cgagcttcga agaacacttg ttgttagagc aggactcagt
     2101 attaggatat ttgtgccaat taaaggtcgt cctgctcctg aagtgacatg gaccaaagat
     2161 aacatcaacc tgaaaaaccg agccaacatt gaaaatacgg aatcatttac tcttctgatt
     2221 atcccagaat gtaacagata tgataccggt aaatttgtca tgaccattga aaacccggct
     2281 gggaagaaaa gtggctttgt gaacgtcaga gtcttggaca cggccaggcc cagtcctcaa
     2341 ctgcggccta cagacatcac aaaggacagt gtcaccctgc actgggacct ccctctgata
     2401 gatggaggct cacgtataac aaactacatt gtagagaaac gtgaagcaac acggaaatct
     2461 tattccacag ccaccactaa gtgccataaa tgcacatata aagttaccgg cttgtctgaa
     2521 gggtgtgaat atttcttcag agtgatggca gagaatgaat atggaattgg tgagccaaca
     2581 gaaactacag agcccgtaaa agcctctgaa gcaccatctc caccagacag ccttaacatc
     2641 atggacataa ctaagagcac cgtcagcctg gcatggccta agcccaaaca cgatggtggc
     2701 agcaagatca ctggctatgt gattgaagcc caaagaaaag gctctgacca gtggacccac
     2761 atcacaaccg tgaaagggtt agaatgtgtt gtgaggaatc taactgaagg agaggaatat
     2821 accttccaag tgatggcagt gaacagcgcg gggagaagtg cccctagaga aagcagaccc
     2881 gtcattgtca aggagcagac aatgcttcca gagctggatc tccgtggcat ctatcagaaa
     2941 ctggtcattg ccaaagctgg tgacaacatc aaagttgaaa ttccagtgct cggtcgaccg
     3001 aagcccacag tgacatggaa aaaaggagac caaattctta aacagacaca gagagttaat
     3061 tttgaaacca cagcgacttc aaccatttta aatatcaatg agtgtgtcag aagtgatagt
     3121 gggccctatc cattaacagc aaggaacatt gtaggagagg ttggtgatgt catcaccatt
     3181 caagtccatg atatcccagg gccacctact ggaccaatca aatttgatga agtttcatct
     3241 gattttgtaa ccttctcttg ggacccacct gagaacgatg gtggtgtacc aataagcaac
//