From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Xenopus laevis peroxisome proliferator activated receptor alpha
Date: 10 Apr 92 10:14:38 GMT
Distribution: bionet
Checksum: 13703     6

LOCUS       XELPPARA     3250 bp ss-mRNA            VRT       10-APR-1992
DEFINITION  Xenopus laevis peroxisome proliferator activated receptor alpha
            (PPARa) mRNA, complete cds.
ACCESSION   M84161
KEYWORDS    nuclear hormone receptor;
            peroxisome proliferator activated receptor.
SOURCE      Xenopus laevis cDNA to mRNA.
  ORGANISM  Xenopus laevis
            Eukaryota; Animalia; Chordata; Vertebrata; Amphibia; Lissamphibia;
            Anura; Archeobatrachia; Pipoidea; Pipidae; Xenopodinae.
REFERENCE   1  (bases 1 to 3250)
  AUTHORS   Dreyer,C., Krey,G., Keller,H., Givel,F., Helftenbein,G. and
            Wahli,W.
  TITLE     Control of the peroxisomal beta-oxidation pathway by a novel family
            of nuclear hormone receptors
  JOURNAL   Cell 68, 879-887 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             108..1532
                     /product="peroxisome proliferator activated receptor
                     alpha"
                     /gene="PPARa"
                     /codon_start=1
                     /translation="MSTIMVDTNSELCILTPLDEDDLESPLSGEFLQDIVDIQDITQT
                     IGDDGSTPFGASEHQFFGNSPGSIGSVSTDLTDTLSPASSPASITFPAASGSAEDAAC
                     KSLNLECRVCSDKASGFHYGVHACEGCKGFFRRTIRLKLVYDRCERMCKIQKKNRNKC
                     QYCRFEKCLNVGMSHNAIRFGRMPRSEKAKLKAEVLMCDQDVKDSQMADLLSLARLIY
                     DAYLKNFNMNKVKARAILTGKASNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEV
                     RIFHCCQCTSVETVTELTEFAKSIPGFTELDLNDQVTLLKYGVYEAMFAMLASVMNKD
                     GMLVAYGNGFITREFLKSLRKPIGDMMEPKFEFAMKFNALELDDSDLSLFVAALICCG
                     DRPGLVNIPSIEKMQESIVHVLKLHLQSNHPDDSFLFPKLLQKMADLRQLVTEHAQLV
                     QTIKKTETDAALHPLLQEIYRDMY"
BASE COUNT      872 a    691 c    771 g    916 t
ORIGIN
        1 ttttgtttgg tctcagcaac ctgaactgga cagcttgact ggactaatga agctttcaaa
       61 gaagtaaaga ccgattaact atgtgatggt ttcgggccag acttgctatg tccaccatca
      121 tggtagacac aaacagcgag ttgtgcattt tgaccccttt ggacgaggat gatctagaga
      181 gtccgctgtc gggagagttc ctgcaggaca ttgtggacat tcaggacatc actcagacca
      241 ttggggacga tggctcaaca ccttttggtg cctccgagca tcagttcttc ggaaacagcc
      301 ctgggtcgat cggatctgtc agcactgacc ttacagacac cttatctccc gcatctagtc
      361 cggcttccat caccttccct gcggcttcgg gtagcgcaga agacgcggcc tgtaagtctc
      421 taaacctcga gtgccgggtg tgcagtgaca aggcctctgg gttccattat ggagttcacg
      481 cttgtgaggg gtgcaagggc tttttccgga ggacgatcag actcaagctg gtgtacgacc
      541 ggtgtgagcg aatgtgtaag atacagaaga agaaccgcaa caagtgccaa tactgtcgct
      601 tcgaaaagtg ccttaatgtt ggaatgtccc acaatgcaat acgatttggg agaatgccac
      661 ggtcggaaaa ggcgaaactg aaagcggaag tcctaatgtg tgaccaggat gtgaaggatt
      721 cgcagatggc cgacctcctc tcactcgcca ggctcattta cgatgcctat ctaaagaact
      781 tcaacatgaa caaagttaaa gccagagcca tcctgacggg gaaagccagc aatccgccct
      841 ttgttataca cgacatggaa acgctgtgca tggcggagaa aacattggtt gcgaagctgg
      901 tggccaatgg catccagaac aaggaggcgg aggtgcggat cttccactgc tgccagtgca
      961 cctcagtgga gacggtcaca gaactgacag agtttgccaa atccatccca ggcttcaccg
     1021 agctggacct caatgatcaa gtgactttgt taaaatacgg ggtctacgag gccatgtttg
     1081 ccatgctggc gtctgtgatg aacaaagatg ggatgctggt ggcatacggg aacggtttca
     1141 ttacgcggga gttcttgaag agcctaagga agccgatcgg ggacatgatg gagccgaagt
     1201 ttgagtttgc catgaagttc aacgcattgg agctggacga cagtgaccta tctctgtttg
     1261 tagcagcact catttgctgt ggagatcgcc ccggattggt gaacattccc agtatagaga
     1321 aaatgcagga gagcatcgtc catgtcctta aactccacct ccagtcaaat caccctgacg
     1381 acagcttcct cttccctaaa ctgctgcaga aaatggccga cctgcggcag ctggtgacgg
     1441 aacacgcgca gctcgtgcag accatcaaaa agactgagac agatgccgcc ctccatccgt
     1501 tactgcaaga aatctacagg gacatgtact gagagctcgt tggttttcat gctatatata
     1561 tatttttttc ggttttctgt aagggagcaa aatctgcaga attagggttt attttcctgt
     1621 gccttctctt ccagctgcag tgacacttct gacaatgtgc actacagttc ctgctgcgaa
     1681 tataacagac aatctgccgg ggtggggggg gtgacactac acaaccacaa catttggatt
     1741 cgaagattta caactattat ttttatgcaa tttgactgaa gacgagtatg gcgtaaatac
     1801 tgtacatcga ctctccaagt ggcgtcagtg ttgaggcgac cgtccaaaag ttttaaatcc
     1861 ggtttgtaaa tagcaatttc cgataagctc cgatggcggc ttcattaagc gcctccgctg
     1921 aatgtacaaa gggtactatc ttgaagatga tgttttgatt gggtaacagg atcttgcttc
     1981 accctccccc ttaaatacta caatttctac ctttttccgt agtcaaatga tgttggaagg
     2041 cttcacagct gcacattatt cgaattgtgt ccgggcgtat gggtgctgaa tcctattggt
     2101 gtaataaggg aggatttttg ccagtatacc catattttag atgatttccg ttaaaggaac
     2161 agggatcttt tgcacatgag gtggattgtt tttaaaggga aaatgtacct tattaatata
     2221 atttccttga aatgtttaat cgggaaactg cggcgaaggt gcacgcagtg tccaattgtg
     2281 ttcagtaata tgtgcggtag ctgccatact gtgtgctccg ataatcacca atgcagcagc
     2341 ttagaaggga tgttggtcgg tatccatatc aaccaggtaa ttgtttaaat gccaaaccgg
     2401 aaaccataaa acaggaataa atgaacataa caaaaaaagt tttcaaagat ttcaaggtag
     2461 aaaaagattt tgggggtttg ggctgaaaac catttgctcc gctaatcctg tttgctagct
     2521 catatgcaca actgactgtc actgtcaaag aacttagaag gaggctgctt gaataccact
     2581 ttgcgcaagc cacttcctat ttcgagtatt catgaatatt ttgactccat tagtaattgc
     2641 tcctaatgaa ctgcttcttc cagaatcccg agactggcgg gggtggcagt tgtcgtgcaa
     2701 attgactcca gggttattga accatcctta tttctgaatt ttcatcaacg aaatttctga
     2761 aattttttcc taatttcgtt tgggaatctt cggcgaatca tcgagacctc aataaactaa
     2821 agattggggg tcaaaaaaga caggaattat actatttatt ttggaggaat atattttttg
     2881 gatgaatttt agattttatg gctatgaacc actatcgtat gaatgaacag aagagaaaaa
     2941 ctattttctg atgctgtcgg gttacttaat atttttgaaa tgacttgcca cttctatttt
     3001 cagataatct tggatggatg aatttggact gtatttatac caaatgcact gcttatcact
     3061 tagaaatggt attttgttct cagggatcac cttttttgtc aattcttggt gtttttttgg
     3121 cctagttttt aagcttgcaa tgtttctcgt ccgtcaaacc agcaccttca tgagatgttc
     3181 tgaatgtttc tgtgatctcc taagtcacaa gctgctttag aaaaatttgt ctttgataaa
     3241 tctgttttcc
//