From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: P.pygmaeus immunoglobulin alpha constant region gene for
Date: 28 Jul 92 10:07:40 GMT
Distribution: bionet
Checksum: 33249     7

LOCUS       ORAIGACR     2739 bp ds-DNA             PRI       28-JUL-1992
DEFINITION  P.pygmaeus immunoglobulin alpha constant region gene for
            alpha-immunoglobulin heavy-chain constant region
ACCESSION   X53704
KEYWORDS    direct repeat; hinge region; immunoglobulin alpha chain;
            immunoglobulin-alpha heavy-chain constant (C) region.
SOURCE      Pongo pygmaeus DNA.
  ORGANISM  Pongo pygmaeus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Pongidae.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Kawamura,S., Tanabe,H., Watanabe,Y., Kurosaki,K., Saitou,N.,
            Omoto,K. and Ueda,S.
  JOURNAL   Mol. Biol. Evol. 8, 793-793 (1991)
  STANDARD  simple staff_entry
COMMENT     *source: clone_library=genomic; *source: clone=ch28.PP.Ig alpha.26;
            *source: is_germline=Y;
            Related sequence: X53385
            From EMBL    entry PPIGACR;  dated 29-NOV-1991.
FEATURES             Location/Qualifiers
     5'UTR           <1..290
     mRNA            join(291..596,807..1160,1384..1778)
                     /gene="immunoglobulin alpha constant region"
     CDS             join(291..596,807..1160,1384..1778)
                     /product="alpha-immunoglobulin heavy-chain constant
                     region"
                     /gene="immunoglobulin alpha constant region"
                     /codon_start=3
                     /translation="SPTSPKVFPLNFCSIQPDGNVVVACLVQGFFPQEPLSVTWSESG
                     QGVTARNFPPSQDPTGGLYTTSSQLTLPATQCQDGKSVTCHVKHYTNPSQDVTVPCRV
                     PRPTPTPSTPPCPPPSCGQPQLSLHRPALEDLLLGSEANLTCTLTGLTNASGATFTWT
                     PSSGKNAVQRPPERDLCGCYSVSSVLPGCADPWNHGQTFTCTAEHPELKTQLTATLSK
                     SGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTW
                     ASRQEPSQGTTTYAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPT
                     HVNVSVVMAEVDGTCY"
                     /partial
     exon            291..596
                     /number=1
                     /note="CH1"
     intron          597..806
                     /number=1
     repeat_region   793..807
                     /rpt_type=direct
                     /note="hinge region"
     exon            807..1160
                     /number=2
                     /note="CH2"
     repeat_region   808..816
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   817..831
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   826..840
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   841..855
                     /rpt_type=direct
                     /note="hinge region"
     intron          1161..1383
                     /number=2
     exon            1384..1778
                     /number=3
                     /note="CH3"
     polyA_signal    1803..1808
BASE COUNT      535 a    922 c    830 g    452 t
ORIGIN
        1 gagctcaggg gactcagcca ctccatggca gagccctgtt taatacaact tgtgtctggg
       61 atggcctggg tcagaggccc tatctaagga gcatgttcag aaaccgtgtc actgggatca
      121 gagagctggg tccaaccgca ggaccgtggt gcaggagctg tgtgaccttg gggccatcac
      181 caggcctctc tgtgctggat tcctccagtg tagaggagag gcaggcacag cctgtcctcc
      241 tggggacatg gcatgagggc cgtgtcctca cagcgcattc tgtgttccag catccccaac
      301 cagccccaag gtcttcccac tgaacttctg cagcatccag ccagatggga acgtggtcgt
      361 cgcctgcctg gtccagggct tcttccccca ggagccactc agtgtgacct ggagcgaaag
      421 cggacagggc gtgaccgcca gaaacttccc acccagccag gatcccaccg gcggcctgta
      481 caccacgagc agccaactga ccctgccggc cacacagtgc caggacggca agtccgtgac
      541 atgccacgtg aagcactaca cgaatcccag ccaggatgtg actgtgccct gcagaggtca
      601 gaggacaggc tggggagtgg ggcggggcca ccccgtcctg ccctgacact gcacctgcac
      661 ccgtgttccc cacagggagc cgcccgtcac tcacaccaga gtggaccacg ggctgagccc
      721 caggaggtgg tggacaggcc aggaggggcg aggcgggggc acggggaagg gcgtgctgac
      781 cagctcaggc catttctcca ctccagttcc ccgacctacc ccaactccct caactccacc
      841 ttgcccacct ccctcatgtg gccagcccca actgtcgctg caccgaccgg ccctcgagga
      901 cctgctctta ggttcagaag cgaacctcac atgcacactg accggcctga caaatgcctc
      961 gggtgccacc ttcacctgga cgccctcaag tgggaagaac gctgtgcaac ggccacctga
     1021 gcgtgacctc tgtggctgct acagcgtgtc cagtgtcctg cccggctgtg ccgacccatg
     1081 gaaccatggg cagactttca cctgcactgc tgagcacccc gagttgaaga cccagctaac
     1141 tgccaccctc tccaagtccg gtgggtccag accctactcg gggccctgct cagtgtcctg
     1201 gtttgcaaaa catattcccg gcctgcctcc tccctcccag tcctgggctc gggtgatcat
     1261 gccaagtaca gagggaaact gaggcaggct gagggggcca ggacacagcc tggggtgtcc
     1321 accggagcag aggggctctc tcatcccctg cccagccccc tgacctggct ctctaccctc
     1381 caggaaacac gttccggccc gaggtccacc tgctgccgcc gccgtcggag gagctggccc
     1441 tgaacgagct ggtgacgctg acgtgcctgg cacgcggctt cagccccaag gacgtgctgg
     1501 ttcgctggct gcaggggtca caggagctgc cccgcgagaa gtacctgact tgggcatccc
     1561 ggcaggagcc cagccagggc accaccacct acgctgtgac cagcatactg cgcgtggcag
     1621 ccgaggactg gaagaagggg gacaccttct cctgcatggt gggccacgag gccctgccgc
     1681 tggccttcac acagaagacc atcgaccgcc tggcgggtaa acccacccac gtcaatgtgt
     1741 ctgtggtcat ggcggaggtg gacggcacct gctactgagc cgcccgcctg tccccagccc
     1801 tgaataaact ccatgctccc ctaagcagcc ccacgcttcc atctggcgcc tgtctgtcca
     1861 tcctcagggt ctcagcacat gggaaagggc cagggcacga aaagggaaga ataccccctg
     1921 ccctgagcct cgggggcccc tggcaccccc atgagccttt ccaccctggt gtgagtgtga
     1981 gttgtgagtg tgagagtgtg tggtgcagga ggcctcgctg gtgtgaaatc ttaggtctgc
     2041 cgaggcaggc acagcccagg gtgggttctg agagacgcac atgccccgga gagttctgag
     2101 tgggcagtgg catggccgtt tgtccctgag agagccgcct ctggctgcag ctgggaggga
     2161 atagggaggg tgagaggagc aggctggcgg agaaagaggc aggtagtggg aggagcggcg
     2221 agggagtgag gggctggact ccagggcccc actgggagga caagctctgg gagggcccca
     2281 cccccctagt gggtggcctc aggacgtccc actgacgcgt gcagaaaggg gcacctcccg
     2341 ctaaccacac tgctctgtac cacactgctc tgtacggggc acgtgggcac agtgcacaat
     2401 cacactcaca tatacgcctg agccctgcag gagcagaacg ttcacagccc agacatagct
     2461 ccagaaagga caggggagtc ccctcccaag cccccagcgg gcattcccag gctcagcctg
     2521 ctcccccagg cccctctggc ctccctgtgt ttccactgtg cacagctcag ggatcaactc
     2581 cacagacccc tcccaggcag cccctgctcc ctgcctggcc aagtctccca tcccttccta
     2641 agcccaacta ggacccaaag catagacagg gagggaccgc atggggtggc atcagaagca
     2701 gcccagtgag ccagggcctg cccagggccc tctgcatgc
//