HDTenEightyP/NetNews huggingface dataset:
From: bwc@raven.imgen.bcm.tmc.edu (Robert Cottingham)
Newsgroups: bionet.molbio.gene-linkage
Subject: Re: Need distances between DXS294 and surronding markers.
Date: 22 Jul 1992 23:26:59 GMT
Reply-To: bwc@bcm.tmc.edu
Originator: bwc@raven.imgen.bcm.tmc.edu


Matts, we recently published a paper

  author = "Tim H.-M. Huang and Robert W. Cottingham Jr. and
                David H. Ledbetter and Huda Y. Zoghbi",
  title = "Genetic Mapping of 4 Dinucleotide Repeat Loci {DXS}453, {DXS}458,
                {DXS}454, and {DXS}424 on the {X} Chromosome Using Multiplex
                Polymerase Chain Reaction",
  journal = "Genomics",
  year = "1992",
  volume = 13,
  pages = "375-380",

which contains the following map in the region you are interested in.

         5.8         13.4          17.8         5.0 cM
DXS454 ------ DXS17 ------ DXS424 ------ DXS42 ------ HPRT

Hope this helps.

-Bob
Newsgroups: bionet.molbio.gene-linkage
From: cmartin@kean.ucs.mun.ca
Subject: software wanted
Organization: Memorial University. St.John's Nfld, Canada
Date: Thu, 23 Jul 1992 18:38:45 GMT

	Does anyone know how to get software that allows mode of 
inheritance model-fitting of dichotomous data (ie. given a pedigree 
with individuals specified only as affected/unaffected the software 
can determine the mode of inheritance)?

	I have heard of the Pedigree Analysis Package (PAP) and would 
appreciate info on how to track down the latest version.  However, I 
would also be interested in other packages.  VAX-VMS or PC versions 
are both suitable.  Thanks.

			Christopher Martin
			Faculty of Medicine
			Memorial University of Newfoundland
			St. John's, Newfoundland
			Canada  A1B 3V6
From: dcurtis@crc.ac.uk (Dr. David Curtis)
Newsgroups: bionet.molbio.gene-linkage
Subject: Re: software wanted (segregation analysis)
Date: 26 Jul 92 09:43:53 GMT
Distribution: bionet
Organization: MRC Human Genome Resource Centre

The question is how to fit a mode of inheritance given affection data in
a pedigree - this is called segregation analysis.  A program I have used
to do this is called POINTER.  It implements the mixed model of Morton
and Maclean, and can compare single gene to multifactorial hypotheses. 
It can also provide best estimates for the transmission parameters of
the major locus.  I expect if you contacted Newton Morton
(nmorton@uk.ac.crc or @crc.ac.uk) he could let you know where you might
obtain it.  I gather he is in the process of updating it.  (Actually,
pedigrees have to be broken down into nuclear families with "pointers".)

I believe one can also perform a segregation analysis with ILINK (from
the LINKAGE programs of Ott et al). I must confess I haven't done this
myself. Instead of iterating over map position the penetrance parameters
can be iterated to maximise the likelihood of the observed affection
pattern. The disadvantage would be that one cannot compare single locus
with multifactorial transmission, only get the best-fitting parameters
for the former.


Dave Curtis

Academic Department of Psychiatry,    Janet:       dcurtis@UK.AC.CRC
St. Mary's Hospital,                  Elsewhere:   dcurtis@CRC.AC.UK
Praed Street, London W2.              EARN/Bitnet: dcurtis%CRC@UKACRL
Tel 071-725 1993                      Usenet: ...!mcsun!ukc!mrccrc!D.Curtis
From: mfarrall@crc.ac.uk (Martin Farrall)
Newsgroups: bionet.molbio.gene-linkage
Subject: Re: software wanted
Date: 24 Jul 92 09:26:47 GMT
Reply-To: mfarrall@crc.ac.uk (Martin Farrall)
Organization: MRC Human Genome Mapping Project Resource Centre, Harrow, UK

PAP is distributed and maintained by:

Sandra J. Hasstedt
Dept. Human Genetics
School of Medicine
501 Wintrobe Building
Salt Lake City, Utah 84132, USA
phone  (801) 581 4422
e-mail sandy@utahmed.bitnet or sandy%msscc@cc.utah.edu
From: dcurtis@crc.ac.uk (Dr. David Curtis)
Newsgroups: bionet.molbio.gene-linkage
Subject: Combining two-point lod scores (FASTMAP)
Date: 23 Jul 92 16:36:36 GMT
Organization: MRC Human Genome Resource Centre

I've had problems posting this - apologies if it appears more than once.

I have been working on an algorithm to combine two-point lod scores to
get a quick approximation to the multipoint lod. I have now come up with
something which (in my opinion) performs reasonably well. It is
certainly extremely fast compared to LINKMAP, and generally produces an
unbiased approximation with an error that may be acceptable for many
applications. Certainly I have found it useful in carrying out my own
exploratory analyses, though I might want to check any crucial results
with LINKMAP before publishing them.

The algorithm has been submitted to Human Heredity, but I have now got
to the stage where I am prepared to distribute FASTMAP, the program
which implements it, more widely so that other people can evaluate its
performance in practice (and hopefully also benefit from the use of it). 
The DOS executable and C source file have been submitted to Dan Davison's
gene-server collection, where it is available as follows:

 62484 Jul 18 12:01 fastmap.aa   
 62524 Jul 18 12:01 fastmap.ab
 51210 Jul 18 12:01 fastmap.ac

These files have been PKZIP'ed, uuencoded and shar'ed. As well as being
available from the mail-server at gene-server@bchs.uh.edu they have also
been forwarded to mirror sites at the EMBL, nic.fun.com and uibio
archives. I would prefer that people obtained it from an archive, but
anyone who has difficulty can contact me directly. I would very much
welcome feedback concerning its performance.

Please note that the graph-drawing program with which it interfaces,
EASIGRAF, is an updated version of the EASIPLOT program available from
the same archives. The latter can be used instead fo rthe present. I aim to
get round to posting EASIGRAF and an updated version of the EASISTAT
package to these archives shortly.

Incidentally, for those using PEDRAW, version 1.4 has also been posted
as pedraw14.aa to pedraw14.af.


Dave Curtis

Academic Department of Psychiatry,    Janet:       dcurtis@UK.AC.CRC
St. Mary's Hospital,                  Elsewhere:   dcurtis@CRC.AC.UK
Praed Street, London W2.              EARN/Bitnet: dcurtis%CRC@UKACRL
Tel 071-725 1993                      Usenet: ...!mcsun!ukc!mrccrc!D.Curtis
Newsgroups: bionet.molbio.gene-linkage
From: dcurtis@crc.ac.uk (Dr. David Curtis)
Subject: Re: software wanted
Organization: MRC Human Genome Resource Centre
Date: Fri, 24 Jul 1992 12:38:52 GMT
From: cliff@evax9.eng.fsu.edu (CLIFF BROWNING)
Newsgroups: bionet.molbio.ageing
Subject: Re: Who reads this newsgroup?
Date: 22 Jul 92 07:47:10 GMT
Reply-To: cliff@evax9.eng.fsu.edu
Organization: Florida State University Computing Center
News-Software: VAX/VMS VNEWS 1.3-4

In article <1992Jul16.075538.12472@fel.tno.nl>, qb7g6@fel.tno.nl (Maarten Landzaat) writes...
>I have a friend working at the Dutch TNO IVEG. When I told her about
>bionet.molbio.ageing, she said she never heard of it. She told me 
>nearly all communication is done by plain mail and phone. She was
>very interested in the newsgroup and would consider getting access to the
>internet.
> 
>I have a few questions:
> 
>Who reads/uses this newsgroup?

Everyone is interested in aging. I know a lot of people here read it every day.

> 
>Who started this newsgroup?

Who knows.

> 
>Why is number of postings so low? (I'm quite new to news, so maybe it's just
>my site).
> 
I don't think that a lot of people that read this group know a lot about 
ageing from a clinical point of view, so they don't feel qualified to make 
sweeping statments, or hopithize. They're probably like me, they read 
everything you can, try to filter out the garbage, and use what's left to try 
and stay as young and healthy for as long as possible.

Cliff Browning                    |      Please deposite another quarter.
Computer Jockey                   |      This ride ends on the next go 'round.
Outer space docking station:      |
Famu/Fsu College of Engineering   |      
Room 118                          |        
                                  |      Disclaimer: Nope, never saw her before
E-mail: Cliff@evax.eng.fsu.edu    |                  before in my life.
        Cliff@avm.bitnet          |
        Cliff::evax               |
                                  |
Phone: We don't need no stinken' phone!
Organization: Senior, Chemical Engineering, Carnegie Mellon, Pittsburgh, PA
Newsgroups: bionet.jobs,misc.jobs.resumes
Date: Mon, 27 Jul 1992 13:07:46 -0400 
From: Ravi Kumar Chopra <rc0i+@andrew.cmu.edu>
Subject: Medical Research or Chem. Eng. position saught.

Ravi Chopra
5541 Pocusset St. 
Pittsburgh, PA 15217-1912
Ph# (412) 521-5676

I just graduated from Carnegie Mellon University with a BS in Chemical
Engineering, concentration in Biomedical Engineering.  I plan to begin
attending medical school in Septerber 1993, and need a job until then,
preferrably in a medically related field.  I am flexible, though, and
would consider a position in Chemical Engineering.

I worked close to two years in Dr. Rakesh K. Jain's Tumor
Microcirculation Laboratory at CMU until it moved to Harvard.  There,
under the guidance of Dr. Yves Boucher, I investigated the effects of
various conditions and therapies on a tumor's interstitial fluid
pressure.  There I got experience in the handling and surgery of
laboratory animals.

For more information about me, please feel free to contact me at this
e-mail address, or the address/phone number indicated above.

Thank you.

Ravi Chopra
Xref: sparky bionet.jobs:387 misc.jobs.offered:9050
From: adh@.uark.edu (Alvis D. Harding)
Newsgroups: bionet.jobs,misc.jobs.offered
Subject: Director of Biometry-Epidemiology Division Available
Date: 23 Jul 92 16:32:33 GMT
Reply-To: adh@.uark.edu
Distribution: na
Organization: Arkansas Children's Hospital, Cardiac Imaging


                                                                 DIVISION DIRECTOR

                                          BIOMETRY-EPIDEMIOLOGY-HEALTH SERVICES RESEARCH


The University of Arkansas for Medical Sciences is seeking a Director for a new Division that will 
have responsibility for teaching and research in biometry, epidemiology and health services research
in the five Colleges at UAMS.  The Director will be a senior investigator with credentials suitable for
appointment at the Associate Professor or Professor level and expertise in one or more of the areas
listed above.  Candidates should have a distinguished record of research productivity and 
extramural support, as well as an ability to work with health professionals at many levels.  The
Director will be expected to recruit additional faculty to fulfill the broad mission of the Division.  
The Director will report directly to the Dean of the College of Medicine.  Potential applicants should
submit a letter of interest and current curriculum vitae to:

Dr. Donald E. McMillan
Chairman:  Search Committee
Department of Pharmacology and Toxicology, Slot 611
University of Arkansas for Medical Sciences
4301 W. Markham St.
Little Rock, AR  72205

UAMS is an Equal Opportunity Employer.

---
-----
Alvis Harding Jr.                                       adh@george.ach.uams.edu
Newsgroups: bionet.jobs
From: JDAI@CCM.UMANITOBA.CA
Newsgroups: bionet.jobs
Subject: Looking for Job
Date: 23 Jul 92 03:23:00 GMT
Distribution: bionet

Loking for job in pharmaceutical/biotechnology Industry
BSc(Pharmacy);MSc(Pharmacology);Ph.D.(Physiology,1993 expected);
one and half year pharmaceutical experience;Enzymology,receptor biology/ligand b
inding;familiar with biomedic[M[D[D[D[D[D[D[D[D[D[D[D[D[D[D
ligand binding;familiar with biomedical statistics and computer skills.

Newsgroups: bionet.jobs
From: smith@phylo.life.uiuc.edu (Steven Smith)
Subject: HARVARD GENOME LABORATORY
Organization: University of Illinois at Urbana
Date: Mon, 27 Jul 1992 20:47:40 GMT


                         DIRECTOR OF COMPUTATION
                        HARVARD GENOME LABORATORY
                           HARVARD UNIVERSITY



The Harvard Genome Lab is seeking  an  experienced  UNIX/Xwindows
programmer with experience in Computational Biology to direct the
analysis of genomic data from the Mycoplasma capricolum project.

The present computational environment at the Harvard  Genome  Lab
is based on the Genetic Data Environment (GDE), a X-Windows based
Graphic User Interface, which allows the seamless integration  of
a  core  multiple  sequence editor with pre-existing external se-
quence analysis programs and internally developed
 programs into a single prototyping environment.  Furthermore, we
have  incorporated  our internal database and automated data con-
trol systems into the Graphic User Interface to handle both  ran-
dom fluorescent sequencing data and genomic walking data from the
Mycoplasma project at the Harvard Genome Lab.  We are now in  the
process  of expanding the database and integrating it into a Pro-
log based system.

The successful candidate would oversee  a  system  administrator,
scientific  programmer  and  a software support technician.  Pro-
gramming duties would include the support of  automated  sequence
analysis,  Integrated Genome databases, and X-Windows based tools
for controlling the production process.

Please submit CV and brief statement of interests via email to

Patrick M. Gillevet
Director  Harvard  Genome  Lab
Harvard University
16 Divinity Ave.  Cambridge, MA  02138

Phone: 617-496-9111
Fax  : 617-495-9300
email:  pat@mito.harvard.edu
From: elizabeth_earle@QMRELAY.MAIL.CORNELL.EDU ("Elizabeth Earle")
Newsgroups: bionet.jobs
Subject: Postdoctoral position avail
Date: 29 Jul 92 09:02:51 GMT
Distribution: bionet


                       Subject:                               Time:4:42 PM
  OFFICE MEMO          Postdoctoral position available        Date:7/29/92
A postdoctoral position is available this September in a USDA-funded project on
transformation of plant cells with yeast artificial chromosomes.  Close
interaction with other postdoctoral associates in the Cornell Plant Science
Center is planned.  Strong molecular biology experience is required; experience
with yeast is desirable but not required.  If interested, send CV, cover
letter, and names of 3 references to Dr. Lisa Earle, Dept. of Plant Breeding,
Cornell University, Ithaca, NY 14853-1902.  Questions about the position can be
directed  either to Dr. Earle (607-255-3102;
Elizabeth_Earle@qmrelay.mail.cornell.edu) or to Dr. Alan Blowers
(315-539-1200).
From: paulr@vaxc.cc.monash.edu.au
Newsgroups: bionet.jobs
Subject: Jobswap mid 93 to USA.Canada from Australia
Date: 23 Jul 92 16:30:41 +1000
Organization: Monash University - Australia.

I am a systems programmer working in a scientific/educational environment and am interested
in the possibility of a one year job swap to USA or Canada. Any interested
people should email me
From: alvs@hm.varikom.lt.su (Alvydas Spokauskas)
Newsgroups: bionet.jobs
Subject: (none)
Date: 29 Jul 92 21:19:35 GMT
Distribution: bionet
Organization: Private

Dear Sysop,
Subscribe me, please, on BIOJOBS conference.
Thank you. Alyvdas Spokauskas.
-- 

Alvydas Spokauskas              |  Institute of Biotechnology "Fermentas"
e-mail: alvs@hm.varikom.lt.su   |  Fermentu 8,
phone: (+7-0122) 751-464        |  2028 Vilnius
Newsgroups: bionet.jobs,sci.bio.technology
From:  gal@humgen.siobc.msk.su (Dr. Galina S. Monastyrskaya)
Subject: seeking for a postdoc position.
Date: Thu, 23 Jul 1992 22:14:44 GMT
Reply-To: gal@humgen.siobc.msk.su
Organization: Lab. Human Genome, Shemyakin Institute
Keywords: PCR, sequencing, hybridization, transcription regulation, tissue-specific expression.

                                     Elena O. Marzen, Ph.D.,
                                     Shemyakin Institute of
                                     Bioorganic Chemistry,
                                     Russian Academy of Sciences
                                     ul.Miklukho-Maklaya, 16/10,
                                     117871 GSP-7, Moscow V437,
                                            Russia
                                     Phone: (095)-330-69-92
                                     Fax: (095)-330-65-38

     A  28  years  old  molecular  biologist  seeking  for   the
opportunity in postdoctoral training.
     Experience:  most of gene  engeneering  and   gene   analysis
methods. Among them: cDNA-gene banks construction, various types
of gene banks analysis,  Southern  and  Northern  hybridization,
conventional  methods  of   gene   analysis,   DNA   sequencing,
PCR.
     Research   interests:   tissue-specific    expression    of
eucaryotic  genes  and  mechanisms  responsible for its  regulation,
structure of  regulatory  elements  involved  in  regulation  of
transcription, structure of genes of integral membrane proteins.


Newsgroups: bionet.jobs
From: smith@phylo.life.uiuc.edu (Steven Smith)
Subject: Database Programmer at Harvard
Organization: University of Illinois at Urbana
Date: Tue, 28 Jul 1992 20:34:25 GMT

 Senior Systems Analyst / Database Programmer
        for FlyBase Project at Harvard University, Cambridge

Job description:  Responsibility for major scientific relational database
development program.  Will be required to supervise and participate in the
design and development of a relational database to contain genetic and
molecular data about the fruit fly, Drosophila, a model organism for the Human
Genome Initiative.  The successful candidate will be able to demonstrate
experience and skills in relational database design and the SQL language,
Unix/C programming, and graphical user interface design.  Experience with
server/client distributed applications would be helpful.  Sybase experience
desirable but not required.  Will be required to supervise other system
analysts.  Will be responsible for developing user level documentation.

Preferred background:  M.S. in computer sciences.  At least two years of
relevant database experience.  Basic understanding of genetics and/or
molecular biology desirable.

To apply:  Please send a resume, including the names of three references
together with a sample source code to:

FlyBase
c/o William M. Gelbart
Dept. of Cellular and Developmental Biology
Harvard University
16 Divinity Avenue
Cambridge, MA 02138

or by e-mail to:

WILLIAM_GELBART@HGL-MAIL.HARVARD.EDU
From: rao@halcyon.usc.edu (Anil Rao)
Newsgroups: bionet.plants
Subject: Mushroom Cultivation: pointers to literature wanted
Date: 31 Jul 1992 13:45:50 -0700
Organization: University of Southern California, Los Angeles, CA
NNTP-Posting-Host: halcyon.usc.edu

Hello all,
  I would be interested in obtaining pointers to any literature on the
cultivation of mushrooms in general and Oyster Mushrooms (Pleurotus florida)
in particular. 

  I'm sorry if this is the wrong newsgroup. I searched my .newsrc and
this seems to be the only newsgroup with "plants" in its title. 

Anil Rao.
rao@halcyon.usc.edu
From: brknig01@uctvax.uct.ac.za
Newsgroups: bionet.plants
Subject: Material req'd: Poaceae
Date: 29 Jul 92 12:58:57 +0200
Summary: Material req'd: Poaceae
Keywords: poaceae, Arundineae, material, grasses, molecular systematics
Organization: University of Cape Town

Hi netters!

I am presently carrying out a molecular study on Arundinoid grasses and
would very much like to make contact with anyone who can collect material 
for me. I am would particularly like to obtain South American and Asian
genera of the tribe Arundineae (sensu Clayton and Renvoize 1986; Genera 
Graminum). This includes genera such as Zenkeria, Danthonia, etc. Also, 
allied genera like Metcalfia, Duthia and Arundoclaytonia would be welcome.

Sources of material need not be natural populations; material from botanic
gardens is suitable.

Please send any details of possible contacts to my email address:

Nigel@chempath.uct.ac.za

All contributors will be acknowledged, and I am willing to provide 
(where possible) plant material of other (southern African) groups
in return. I await in anticipation....

Nigel Barker
Botany Dept.
University of Cape Town
Private Bag
RONDEBOSCH
7700
South Africa
From: ajt@uk.ac.sari.rri (Tony Travis)
Newsgroups: bionet.plants
Subject: Re: Leaf image analysis
Date: 28 Jul 92 12:40:32 GMT
Distribution: bionet
Organization: Rowett Research Institute
Original-To: plantbio@uk.ac.daresbury

In article <Tue.28Jul92.0717.bionet-news@uk.ac.daresbury> you write:
: I am looking for a program for IBM PC which will perform Fourier 
: analyses of digitized leaf outlines.  Any information on this would
: be greatly appreciated.
: Please reply to:
: loverock@sfu.ca

Try reading: West, J.G. and Noble, I.R (1984) Analyses of digitised
leaf images of the Dodonaea viscosa complex in Australia, Taxon, 33,
595-613.

This describes _alternatives_ to fourier-based shape descriptors.

	Tony

--
Dr. A.J.Travis,                       |  Tony Travis
Rowett Research Institute,            |  JANET: <ajt@uk.ac.sari.rri>
Greenburn Road, Bucksburn,            |  other: <ajt@rri.sari.ac.uk>
Aberdeen, AB2 9SB. UK.                |  phone: 0224-712751
From: brwnng@CCWF.CC.UTEXAS.EDU (@ccwf.cc.utexas.edu, Karen Browning)
Newsgroups: bionet.plants
Subject: (none)
Date: 21 Jul 92 22:45:51 GMT
Distribution: bionet

I am looking for a black mexican sweet corn cDNA library in lambda ZAP.  Does
anyone have a library they are willing to share?  Thank you.
Karen S. Browning                      (email) brwnng@ccwf.cc.utexas.edu
Dept. of Chemistry and Biochemistry    (fax)   512-471-8696
The University of Texas at Austin      (phone) 512-471-4562
Austin, TX  78712
From: una@phy.duke.edu (Una Smith)
Newsgroups: bionet.plants
Subject: Re: Leaf image analysis
Summary: Alternatives to Fourier analysis
Keywords: morphometrics leaf shape landmark eigenshape analysis
Date: 28 Jul 92 17:45:58 GMT
Distribution: bionet
Organization: Duke University Physics Dept.; Durham, N.C.

> I am looking for a program for IBM PC which will perform Fourier 
> analyses of digitized leaf outlines.

Two references, both in BibTeX format;  if the proceedings volume
doesn't answer your every question about Fourier analysis, you'll
find references to other work that will.  There are diskettes of
morphometrics software and a chapter on commercial software included
with the book.

@proceedings{morphomet1990,
	year = 1990,
	title = {Proceedings of the Michigan Morphometrics Workshop},
	editor = {F. James Rohlf and J. W. Archie},
	organization = {University of Michigan Museum of Zoology},
	address = {Ann Arbor, Michigan}}

@article{Ray1992},
	author = {Thomas S. Ray},
	year = 1992,
	title = {Landmark eigenshape analysis:  Homologous contours:
		Leaf shape in {\it Syngonium\/} ({A}raceae)},
	journal = {American Journal of Botany},
	volume = 79,
	number = 1,
	pages = {69--76}}

Enjoy!

	Una

-- 

Una Smith   una@phy.duke.edu    School of the Environment
                                Duke University
                                Durham, NC  27706
Newsgroups: bionet.plants,bionet.software
From: dangold1@iastate.edu (Daniel M Goldman)
Subject: Re: Leaf image analysis
Keywords: Fourier analysis/leaf shape
Organization: Iowa State University, Ames IA
Date: Thu, 30 Jul 1992 13:41:13 GMT

In <loverock.712299053@sfu.ca> loverock@fraser.sfu.ca (David Sean Loverock) writes:

>I am looking for a program for IBM PC which will perform Fourier 
>analyses of digitized leaf outlines.  Any information on this would
>be greatly appreciated.
>Please reply to:
>loverock@sfu.ca

>Thanks  

Contact Bob Simons, Cohort Software, Internet e-mail 71161.564@
compuserve.com.  Ask about CoStat and CoPlot.  I have been a very
satisfied user for almost 10 years.  They are wonderful programs.
Feel free to contact me if you have questions -DmG