From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.lar immunoglobulin alpha-1 constant region gene (allele-2) for
Date: 28 Jul 92 10:02:52 GMT
Distribution: bionet
Checksum: 51724     7

LOCUS       GIBIGA1C     2964 bp ds-DNA             PRI       28-JUL-1992
DEFINITION  H.lar immunoglobulin alpha-1 constant region gene (allele-2) for
            alpha-immunoglobulin heavy-chain constant region
ACCESSION   X53708
KEYWORDS    direct repeat; hinge region; immunoglobulin alpha-1;
            immunoglobulin-alpha heavy-chain constant (C) region.
SOURCE      Hylobates lar DNA.
  ORGANISM  Hylobates lar
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hylobatidae.
REFERENCE   1  (bases 1 to 2964)
  AUTHORS   Kawamura,S., Tanabe,H., Watanabe,Y., Kurosaki,K., Saitou,N.,
            Omoto,K. and Ueda,S.
  JOURNAL   Mol. Biol. Evol. 8, 793-793 (1991)
  STANDARD  simple staff_entry
COMMENT     *source: cell_type=leucocyte; *source: clone_library=genomic;
            *source: clone=ch28.HL.Ig alpha.20; *source: is_germline=Y;
            Related sequence: X53387
            From EMBL    entry HLIGA1C;  dated 29-NOV-1991.
FEATURES             Location/Qualifiers
     5'UTR           <1..289
     mRNA            join(290..595,807..1139,1350..1757)
                     /gene="immunoglobulin alpha-1 constant region(allele 2)"
     CDS             join(484..595,807..1139,1350..1744)
                     /note="putative CDS"
                     /product="alpha-immunoglobulin heavy-chain constant
                     region"
                     /gene="immunoglobulin alpha-1 constant region(allele 2)"
                     /note="putative"
                     /codon_start=1
                     /translation="MSSQLTLPATQCPDCKSVTCHVNHYTNSSQDVTVPCRVPPSPPC
                     CHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAIQGPPERDLC
                     GCYSVSSVLPGCAEPWKNGKTFTCTAAHPESKTPLTANITKSGGSRRNMFRPEVHLLP
                     PPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTF
                     AVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMAEVDG
                     TCY"
     exon            290..595
                     /number=1
                     /note="CH1"
     intron          596..806
                     /number=1
     repeat_region   796..810
                     /rpt_type=direct
                     /note="hinge region"
     exon            807..1139
                     /number=2
                     /note="CH2"
     repeat_region   811..819
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   820..834
                     /rpt_type=direct
                     /note="hinge region"
     intron          1140..1349
                     /number=2
     exon            1350..1757
                     /number=3
                     /note="CH3"
     polyA_signal    1782..1787
BASE COUNT      578 a    991 c    895 g    500 t
ORIGIN
        1 gagctcaggg gactcagcca ctccatggca gagccctgtt taatataact tgtgtctggg
       61 atggcctggg tcagaggccc tatctaagga gcatgttcag aaaccgtgtc gctgggatca
      121 gacagcaggg tccaaccgca ggcccgtggt gcaggagctg tgtgaccttg gggctgtcac
      181 caggctgtct gtgctgggtt cctccagtat agaggagagg caggcacaga ctgtcctcct
      241 ggggacatgg catgagggcc gcgtcctcac agcgcattct gtgttccagc atccccgacc
      301 agccccaagg tcttcccgct gagcctcgac agcacccagc cagatgggga cgtggtcgtc
      361 gcctgcctgg tccagggctt cttcccccag gagccactca gtgtgacctg gagcgaaagc
      421 ggacagaacg tgaccgtcag aaacttccca cccagccagg atgcctccgg ggacctgtac
      481 accatgagca gccagctgac cctgccggcc acacagtgcc cagactgcaa gtccgtgaca
      541 tgccacgtga atcactacac gaattccagc caggatgtga ctgtgccctg ccgaggtcag
      601 agggcaggct ggggagtggg gcggggccac cccgtcctgc cctgacactg cgcctgcacc
      661 cgtgttcccc acagggagcc gccccgtcac tcacaccaga gtggaccacg ggccgagccc
      721 caggaggtgg tggacaggcc aggaggggcg aggcgggggc atggggaagg gtgttctgac
      781 cagctcaggc catctctcca ctccagttcc cccatctccc ccatgctgcc acccccgact
      841 gtcgctgcac cgaccggccc tcgaggacct gctcctaggt tcagaagcga acctcacgtg
      901 cacactgact ggcctaagag atgcctctgg tgccaccttc acctggacgc cctcaagtgg
      961 gaagagcgct attcaaggac cacctgagcg tgacctctgt ggctgctaca gcgtgtccag
     1021 tgtcctgcct ggctgtgctg agccatggaa gaatgggaag accttcacct gcactgctgc
     1081 ccaccccgaa tccaagaccc cactaaccgc taacatcaca aaatccggtg ggtccagacc
     1141 ctgctcgggg ccctgctcag tgctctggtt tgcaaagcat attcccagcc tgcctcctcc
     1201 ctcccaatcc tgggctccag tgctcatgcc aagtacagag ggaaactgag gcaggctgag
     1261 gggccaggac acagcccggg gtgcccacca gagcagaggg gctctctcat cccctgccca
     1321 gccccctgac ctggctctct accctccagg aaacatgttc cggcccgagg tccacctgct
     1381 accgccgccg tcggaggagc tggccctgaa cgagctggtg acgctgacgt gcctggcacg
     1441 tggcttcagc cccaaggacg tgctggttcg ctggctgcag gggtcacagg agctgccccg
     1501 tgagaagtac ctgacttggg catcccggca ggagcccagc cagggcacca ccaccttcgc
     1561 tgtgaccagc atactgcgcg tggcagccga ggactggaag aagggggaca ccttctcctg
     1621 catggtgggc catgaggccc tgccgctggc cttcacacag aagaccatcg accgcctggc
     1681 gggtaaaccc acccatgtca atgtgtctgt tgtcatggcg gaggtggacg gcacctgcta
     1741 ctgagccgcc cgcctgtccc cacccctgaa taaactccat gctcccccaa gcagccccac
     1801 gcttccatcc ggcgcctgtc tgtccatcct cagggtctca gcacttggga aagggccagg
     1861 gcatggacag ggaagaatac cccctgccct gagcctcggg gggcccctgg cacccccatg
     1921 agcctttcca ccctgatgtg agtgtgagtt gtgagtgtga gagtgtgtgg tgcaggaggc
     1981 ctcgctggtg tgagatctta ggtctgccga ggcaggcaca gcccagggtg ggttctgaga
     2041 gacgcacatg ccccggagag ttctgagtga gcagtggcac ggccgtttgt ccctgagaga
     2101 gccgcctctg gctgtagctg ggagggaata gggagggtaa aaggagcagg ctagccaaga
     2161 aaggcgcagg tagtgggagg agcggcgagg gagtgagggg ctggactcca gggccccact
     2221 gggaggacaa gttccaggag ggccccacca ccctagtggg tgggcctcag gacgtcccac
     2281 tgatgcatgc agaaaggggc acctcccctt aaccacactg ctctgtacgg ggcacgtggg
     2341 cacacgtgca cactcacact cacgtatacg cctgagccct gcaggagcgg aacgttcaca
     2401 gcccagaccc agttccagaa aagccagggg agtcccctcc caagccccca agctcagcct
     2461 gctcccccag gcccctctgg cttccctgtg tttccactgt gcacagctca gggaccaact
     2521 ccacagaccc ctcccaggca gcccctgctc cctgcctggc caagtctccc atcccttcct
     2581 aagcccaact aggacccaaa gcatagacag ggaggggccg tgtggggtgg catcggaagc
     2641 aagccagtga gacagggcct gcccagggcc ctctgcatgc ctctggcttc tgcctggggc
     2701 tcccaggagt gaaagaacag tcccacaacc actgtgggga cacctggcac ccggactccc
     2761 acaagggggc agtggggccc ctgctcgtgc cttagacatc ttctgggcct ccccaagggc
     2821 ccccgccttc tggctgcctc cctctgctct cagggccaag gtgaggtgga ggccactgtc
     2881 acccctgagg gtccagtcac cagagggtaa ttgagagcaa caggtcactc agggaagccc
     2941 tgccacagag aagccctcca gccc
//