From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human macrophage mannose receptor gene, exon 30.
Date: 7 Jan 93 05:48:55 GMT
Distribution: bionet
Checksum: 55474 8

LOCUS       HUMMANR30    1206 bp ds-DNA             PRI       06-JAN-1993
DEFINITION  Human macrophage mannose receptor gene, exon 30.
ACCESSION   M93221
KEYWORDS    mannose receptor.
SEGMENT     30 of 30
SOURCE      Homo sapiens Female Placenta DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Taylor,M.E., Conary,J.T., Lennartz,M.R., Stahl,P.D. and
            Drickamer,K.
  TITLE     Primary structure of the mannose receptor contains multiple motifs
            resembling carbohydrate-recognition domains
  JOURNAL   J. Biol. Chem. 265, 12156-12162 (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1206)
  AUTHORS   Kim,S.J., Ruiz,N., Bezouska,K. and Drickamer,K.
  TITLE     Organization of the gene encoding the human macrophage mannose
            receptor (MRC1)
  JOURNAL   Genomics 14, 721-727 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            58..1005
                     /number=30
                     /gene="mannose receptor"
                     /citation=[1]
                     /note="Coding region entails transmembrane region and
                     cytoplasmic tail; putative"
     3'UTR           309..1005
                     /gene="mannose receptor"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
     polyA_site      1005
                     /gene="mannose receptor"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
     intron          order(M93220:210..379,1..57)
                     /number=29
                     /gene="mannose receptor"
     mat_peptide     join(M93192:282..288,M93193:26..427,M93194:93..266,
                     M93195:287..451,M93196:116..229,M93197:156..302,
                     M93198:69..254,M93199:76..233,M93200:117..227,
                     M93201:8..123,M93202:60..208,M93203:28..227,
                     M93204:148..275,M93205:49..136,M93206:27..171,
                     M93207:233..274,M93208:103..266,M93209:124..191,
                     M93210:32..132,M93211:91..236,M93212:42..156,
                     M93213:86..252,M93214:192..294,M93215:38..270,
                     M93216:18..183,M93217:39..188,M93218:233..346,
                     M93219:34..198,M93220:168..209,58..305)
                     /product="mannose receptor"
                     /gene="mannose receptor"
                     /codon_start=1
     mRNA            join(M93192:125..288,M93193:26..427,M93194:93..266,
                     M93195:287..451,M93196:116..229,M93197:156..302,
                     M93198:69..254,M93199:76..233,M93200:117..227,
                     M93201:8..123,M93202:60..208,M93203:28..227,
                     M93204:148..275,M93205:49..136,M93206:27..171,
                     M93207:233..274,M93208:103..266,M93209:124..191,
                     M93210:32..132,M93211:91..236,M93212:42..156,
                     M93213:86..252,M93214:192..294,M93215:38..270,
                     M93216:18..183,M93217:39..188,M93218:233..346,
                     M93219:34..198,M93220:168..209,58..1005)
                     /product="mannose receptor"
                     /gene="mannose receptor"
     CDS             join(M93192:228..288,M93193:26..427,M93194:93..266,
                     M93195:287..451,M93196:116..229,M93197:156..302,
                     M93198:69..254,M93199:76..233,M93200:117..227,
                     M93201:8..123,M93202:60..208,M93203:28..227,
                     M93204:148..275,M93205:49..136,M93206:27..171,
                     M93207:233..274,M93208:103..266,M93209:124..191,
                     M93210:32..132,M93211:91..236,M93212:42..156,
                     M93213:86..252,M93214:192..294,M93215:38..270,
                     M93216:18..183,M93217:39..188,M93218:233..346,
                     M93219:34..198,M93220:168..209,58..308)
                     /gene="mannose receptor"
                     /product="mannose receptor"
                     /codon_start=1
                     /translation="MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAV
                     QTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWEC
                     KNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLL
                     GNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSES
                     LWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSG
                     LWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQ
                     KLGYICKKGNTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCR
                     KEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLR
                     GEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGW
                     KKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTG
                     LSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFV
                     CKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRA
                     LGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWA
                     YGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPP
                     VTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDA
                     QSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINC
                     GYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQE
                     ARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHY
                     TNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLT
                     NPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQM
                     ETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHC
                     NESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLE
                     CLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNW
                     NTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRK
                     MDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSP
                     GTSDMKDLVGNIEQNEHSVI"
BASE COUNT      372 a    205 c    214 g    415 t
ORIGIN      
        1 gcatgcaacc ctctgcctcc ctcccacgtt ttccataatg attttattta tttatagctg
       61 acacaaggaa gatggaccct tctaaaccgt cttccaacgt ggccggagta gtcatcattg
      121 tgatcctcct gattttaacg ggtgctggcc ttgccgccta tttcttttat aagaaaagac
      181 gtgtgcacct acctcaagag ggcgcctttg aaaacactct gtattttaac agtcagtcaa
      241 gcccaggaac tagtgatatg aaagatctcg tgggcaatat tgaacagaat gaacactcgg
      301 tcatctagta cctcaatgcg attctgagat atttgaattt cataaaattg taactgaaat
      361 ttaaaatttt tagttcaatg tgattgtttt ctttaaaatg agtactgaat tgtactggtc
      421 tgtccttttt tcctttgcct aattgaagaa ataattgctt gttttctagc ctggcaagat
      481 attttcataa aagagggata acaatgctga ttactacctt ttaaaatatt ttagataaat
      541 gcacagcacc acagcaccac atctaagcat tagtgatggg tagctgatgt cagcttcatg
      601 tggattttaa gcactctaga aacaatgaag cttcttggca tattttaagg agctcccaaa
      661 atgtgttacc tattaaattg taactcagca agtagaagac catttgaaaa gtcaggtaca
      721 aatttcctca agtggcataa aaatgtagtc agttttctct tttaccagtt tttatttcca
      781 ctccaattat ttagaacttt atttgtacat gtgcagaaga ataaggcagc tgagaatctt
      841 gtttccccca agagagtttt acaggctgag tgttgcaaat gtgttctttg tcctgttata
      901 tgtatatcag gaatacaagg atgtgaaata aaactgtaaa tttgcataac tggatgtact
      961 tagataatgt gaaataaaca ttaaagacaa ggtctatttt taatagattt gcattttggt
     1021 gatcttagta taaatttgct tttaaatgag atgtatttat ccactcactt tacactttaa
     1081 cttgacactt atgatattat ttgtagagaa attctttaaa tgaaactcat gaactatttt
     1141 gaaaaggagt gttgctaaaa tgctgtgtgt aaaatgaatt ttttaccgta atgattttgc
     1201 cagatc
//