From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human casein kinase II subunit beta (CSNK2B) gene, complete cds.
Date: 20 Aug 92 10:02:38 GMT
Distribution: bionet
Checksum: 18671    12

LOCUS       HUMCKIIBE    5917 bp ds-DNA             PRI       20-AUG-1992
DEFINITION  Human casein kinase II subunit beta (CSNK2B) gene, complete cds.
ACCESSION   X57152
KEYWORDS    casein kinase I; cytoplasmic protein; nuclear protein.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5917)
  AUTHORS   Voss,A., Wirkner,U., Jacobi,R., Hewitt,N., Schwager,C.,
            Zimmermann,J., Ansorge,W. and Pyerin,W.
  TITLE     Structure of the gene encoding human casein kinase II subunit beta
  JOURNAL   J. Biol. Chem. 266, 13706-13711 (1991)
  STANDARD  full automatic
COMMENT     From EMBL    entry HSCKIIBE;  dated 06-AUG-1991.
FEATURES             Location/Qualifiers
     CDS             join(1634..1705,2672..2774,3344..3459,3906..3981,
                     4128..4317,4645..4735)
                     /EC_number="2.7.1.37"
                     /product="casein kinase II subunit beta"
                     /gene="CSNK2B"
                     /codon_start=1
                     /translation="MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVP
                     HYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQ
                     QGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFG
                     TGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR"
     mRNA            join(683..1011,1623..1705,2672..2774,3344..3459,
                     3906..3981,4128..4317,4645..4875)
                     /note="major start site"
                     /gene="CSNK2B"
                     /evidence=EXPERIMENTAL
     mRNA            join(795..1011,1623..1705,2672..2774,3344..3459,
                     3906..3981,4128..4317,4645..4875)
                     /note="minor start site"
                     /gene="CSNK2B"
                     /evidence=EXPERIMENTAL
     mRNA            join(715..1011,1623..1705,2672..2774,3344..3459,
                     3906..3981,4128..4317,4645..4875)
                     /note="major start site"
                     /gene="CSNK2B"
                     /evidence=EXPERIMENTAL
     GC_signal       328..332
                     /gene="CSNK2B"
     GC_signal       414..418
                     /gene="CSNK2B"
     CAAT_signal     481..487
                     /gene="CSNK2B"
     GC_signal       589..593
                     /gene="CSNK2B"
     exon            683..1011
                     /number=1
                     /gene="CSNK2B"
     GC_signal       698..702
                     /gene="CSNK2B"
     exon            715..1011
                     /number=1
                     /gene="CSNK2B"
                     /evidence=EXPERIMENTAL
     CAAT_signal     759..765
                     /gene="CSNK2B"
     exon            795..1011
                     /number=1
                     /gene="CSNK2B"
     intron          1012..1622
                     /number=1
                     /gene="CSNK2B"
     exon            1623..1705
                     /gene="CSNK2B"
     intron          1706..2671
                     /number=2
                     /gene="CSNK2B"
     repeat_region   1934..2212
                     /rpt_family="ALU"
                     /gene="CSNK2B"
     exon            2672..2774
                     /gene="CSNK2B"
     intron          2775..3343
                     /number=3
                     /gene="CSNK2B"
     exon            3344..3459
                     /gene="CSNK2B"
     intron          3460..3905
                     /number=4
                     /gene="CSNK2B"
     exon            3906..3981
                     /gene="CSNK2B"
     intron          3982..4127
                     /number=5
                     /gene="CSNK2B"
     exon            4128..4317
                     /gene="CSNK2B"
     intron          4318..4644
                     /number=6
                     /gene="CSNK2B"
     exon            4645..4875
                     /gene="CSNK2B"
BASE COUNT     1363 a   1452 c   1672 g   1430 t
ORIGIN
        1 gatctgtcgg ttggggtcct acttttacat aacgccccca caatgccctt cgccttcctc
       61 aacgtggccc ccgctccaag cccattttct ggagccagga atccactctg tgggttagga
      121 aaggccctca ggaggcggag ggaaacctgt ggaatgccga gaagccgtgt aatgaaataa
      181 cggtcacggc ctggcccctc accattactc tgaccagggt tcgaaggtca cacttagagc
      241 ctaaggggaa atggagaagt gcaaagggac gagcagaatg gctggcacca cctcaggtta
      301 gcgcactggg acgttccagt tctcacaccg cccaccccac cccacccaag tcctacgcac
      361 ggagccaagc cgcacctctc ccctcatgag gcaggagccc cggaggaaac agtacgcccg
      421 tcaagggtct ctggcgggac tgattcgcac taggggccca acaggcaata aggacccagc
      481 ggattggccg aggataggcc agtcccctgg gcagcagcgc cgcgccggga ctagagggga
      541 acgtgaggag agctgcggaa agagatccag cctggctccc tcctttcccc gccctaagtc
      601 agcctcttca cccagtgagc acaaaactgt attgcccaga ctcccgggcc ccgaacgcca
      661 tacctggctt ccgcttccgg tggcttctcg ttgtgccccg cccgcaagcg ccctcctccg
      721 ggccttcgtg acagccaggt cgtgcgcggg tcatcctggg attggtagtt cgctttctct
      781 catttagcca gtttctttct ctaccgggga ctccgtgtcc cggcatccac cgcggcacct
      841 gacccttggc gcttgcgtgt tgccctcttc cccaccctcc ctaatttcca ctccccccac
      901 cccacttcgc ctgccgcggt cgggtccgcg gcctgcgctg tagcggtcgc cgccgttccc
      961 tggaagtagc aacttcccta ccccacccca gtcctggtcc ccgtccagcc ggtgagtctg
     1021 aagtcgtcgc tgctccgagt cccttgtcgc tgggagcggc acatggggtc tccggacttt
     1081 gatgtggggc gggggaggaa gcgaccaggt ccggcacgaa ggagggagag gtggcctgag
     1141 gagcggaggg gggatgtgtg gattccggtg aaagggacct gacaatcgcc cccaacccgt
     1201 gagaaaagga ggagcccagt tcttgcttga gaatgataaa cttggaaacc cttgggaaag
     1261 gcgtgggggt catgcagaga cttgtattgg tagggagcct gagtcgaggt ccctgccgga
     1321 gttgacacag aggagagagg gccctggcct tcgggagctc cagggatgtg ggtcgggctg
     1381 gtgggtcaaa gtatctgttg gcttctttca agtggtggga ccccaaagaa tgtttaactt
     1441 caaagaaaag gggctgagat gtaaattaga ggagctggag aggagtgctt cagagtttgg
     1501 gttgctttaa gaaagggtgg ttccgaattc tcccgtggtt ggagggccga atgtgggagg
     1561 agggaggata ccagaggcag ggaaggagaa cttgagcttt actgacactg ttctttttct
     1621 agctgacgtg aagatgagca gctcagagga ggtgtcctgg atttcctggt tctgtgggct
     1681 ccgtggcaat gaattcttct gtgaagtgag ttctcttcaa cctccctact tgccagcttc
     1741 acatatcttc ccaccagacg ttccttcaca tattccactt ctacactgtt ctcttacatg
     1801 ctatttgaaa acttcctatc agcaaagagt cccccctata aaccccgacg aacctgtgct
     1861 aaagtggcaa aactggggcc caagtcctga gtctgccacc gtccagcaat ataacgttgg
     1921 gctagtcaat ttgtgtcttt ttcttttttt tgagactggg tctcactctg tcaccgaggc
     1981 tggagggtag tggtgcgatc tcggcttact gccacctctg cctcccaggt tcaagcgatt
     2041 ctcctgctcc agcctcccaa gtagctggga ttacaagtgc ctgccaccat gcctggctaa
     2101 tttttgtatt tttagtagag acagggtttc actatgttgg caaggctggt ctcgaactcc
     2161 agacctcagg gtgatctgcc tgcctcgggc ctcccaaagt gctgggatta caggcgtgag
     2221 cattgcgccc ggcctgtatc ttttgttact aaagtggcac tgctagtact tgtctcaggt
     2281 ggcctttagg aaaactgaaa tgctacacat tgaaatgttt tgttcagaaa ccatgctgtt
     2341 cagcttccac cttccttagc cagctgagag gacaaaactg gttcctagag acgggataca
     2401 ggagtggagt agggacaaag atcttggaaa agaatgtcta agaaaaagat tgctgtatct
     2461 acttatcctt agaaaagaaa agccaaagct tttatgggag agagtgtagg tgaactaggg
     2521 agagacacaa gtacttctgc tgagttggga gtgagaaaca agcacaacag atgcagttgt
     2581 gttgatgata aggcatcact tagagcattt tgcccaggtc aaagatgagg attttgatat
     2641 gggttccctc ttggcttcca tgtcctgaca ggtggatgaa gactacatcc aggacaaatt
     2701 taatcttact ggactcaatg agcaggtccc tcactatcga caagctctag acatgatctt
     2761 ggacctggag cctggtgagg caccctcagg gttgttttgt gtgtgtgcgt gcactatttt
     2821 tctcttcaaa tctctattca cttgcctgaa ttttgccaaa tttcctttgg ttctctgatt
     2881 tctttaaccc caaattcatg ctttattttg atcctccacc tgactcttgt ctagttttgt
     2941 gacgtatatc acttgttctc atgttttcta aatccgcaat tcagacctat tccaaaatgc
     3001 gtttcctcag ggtctggttt gttgtctgtt tctcctgctt tgcaccttcc agtctagagt
     3061 ttcatcttct gcattgacat tgttgcagtt atgtattgag gagggagttg ggagggagag
     3121 caaggagcag aggctgaaaa ggtgtgaggg gaaggcagag ctgtcttcgt ttgatgcaag
     3181 ggtcagaagc ccaggtttct gggtcccatg cccagatgtt ggatggggta aggcccaaaa
     3241 gtaggtgcta ggcaaactga atagcccgca gcccctggat atgggcaggg cacctaggaa
     3301 agctgaaaaa caagtagttg catttggccg ggctgtggtt cagatgaaga actggaagac
     3361 aaccccaacc agagtgacct gattgagcag gcagccgaga tgctttatgg attgatccac
     3421 gcccgctaca tccttaccaa ccgtggcatc gcccagatgg tgaggcctct ctgctcctac
     3481 ctgcctcctt ctgagcagta agagacacag gttcctgcag caagaagtca tgtttaagcc
     3541 ctgtttaagg aagctagctg agaagagggg aagaacccca gaacttgggc ctgggaattg
     3601 aattctgatt gggggtcatc ctgaagggat tgttttcagg gagggagaca gaccttgaat
     3661 cagagagttg tgatagactg cctcttcctc aaggaacaaa caacaaatgg ctctgatggt
     3721 ttgtagccct gccctaattt ggaagaaagg caacacagaa gtttgagagc ccatctagtc
     3781 cagagaaggg ggcctctgga cagagttgga aggagtgccg acagagttgg tatgggttgg
     3841 gctgcgaagg gagttgcctc ttctttacat ctacctgcca accccttcca ttgtattcac
     3901 ctcagttgga aaagtaccag caaggagact ttggttactg tcctcgtgtg tactgtgaga
     3961 accagccaat gcttcccatt ggtgagtgtt gaagaaggga aaggaaagca ccgtgtggca
     4021 gtcttatggg aaggagttgg ggctcaacac attggagcct gagtcctgag gggaggttag
     4081 gtaggaatag ggggatacct ggcctgctga gtctggctgt ctcccaggcc tttcagacat
     4141 cccaggtgaa gccatggtga agctctactg ccccaagtgc atggatgtgt acacacccaa
     4201 gtcatcaaga caccatcaca cggatggcgc ctacttcggc actggtttcc ctcacatgct
     4261 cttcatggtg catcccgagt accggcccaa gagacctgcc aaccagtttg tgcccaggta
     4321 gggagcaggg agagtcatta agggtcaaag gaaaggccca agatccccca gagaggggag
     4381 gacagggcat ggccctttct tgaggtctgc ttctcccaga atcagggcat ctccctgctg
     4441 agtgactgtg ggaaagttat ttgattatct gtgcttgagt taccttattg tagaatgttc
     4501 ttgagctgag aagttgggaa ccacgaggct ttagctctga gcaggtccat agaggagctc
     4561 aggtggggag gtgggaatgc aggtgactgg cagggcctgg atggggctca tgctgctgcc
     4621 tctctgacct ctgccctggc ctaggctcta cggtttcaag atccatccga tggcctacca
     4681 gctgcagctc caagccgcca gcaacttcaa gagcccagtc aagacgattc gctgattccc
     4741 tcccccacct gtcctgcagt ctttgtcttt tcctttcttt tttgccaccc tttcaggaac
     4801 cctgtatggt ttttagttta aattaaagga gtcgttatcg tggtgggaat atgaaataaa
     4861 gtagaagaaa aggccatgag ctagtctgct ggtgcttgct gttggggaag ggaaggtgat
     4921 ggtgtgttgg actccagggg ccctcatggc ccagcccacc ctccccagat tgaaaaccag
     4981 gacagatttg tgctcagtgg attgggtggt gtttttagta tggagcagaa cagaattcct
     5041 aggactgcgt gtgatgaaat gcaaggtcaa aaggaaaaga caaagcatat ttcaaagatg
     5101 agaaatattt gtttggatat ctatgactgt ctgtttatac tgtaaggggc ttaatcagca
     5161 gctccatctt ttagttttag ttctaaagga aaagtagcct aaagtcagta taactaaagg
     5221 gtggaacgag gtgggacaag gtccggaatt gctgctcagt gatgtgtgtg tgcctgccgc
     5281 tggtggagct gagactgctc actctcagaa ggatggggat gcttgatttc ctggccaggt
     5341 tgtcccagca cagtggggat tggccctgtt gtatgacgaa gacagcacat ggtggcagag
     5401 atagatacta acccatggac tttccaaggg agggaatagg tctttggagg gtatgcaaga
     5461 caaaggtaga cactggataa agaacccggt agtgcccagg tattacccca tctgggccat
     5521 tactcccaca ctcaggaacc agacgttgtg ggtgaggaca tgctgtccct cctgccaagt
     5581 aataacttcc ttcccagcca ggatcctgcc ccaagtagga atatagctct gcatttacag
     5641 cagctcctgc tcagaccttg tcaaaaccac cctgcagctt aggattaagg agcatggtca
     5701 caggaaggtg gggtttcagg gcatcccctc aggaactgcc catctcccca gaattccaaa
     5761 atgaaggtcc atatgcttgt aggtgtgctg gtcatggtgg gctcacagta ggaaagggta
     5821 agtggggccc aggggcaggg agggaggaag gggtaactga gtccaggaag ggggtggagc
     5881 gtggccatgg aaatcgggct ccacggccca gggatgg
//