From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse (clone lambda-c5e) intercellular adhesion molecule 1 (ICAM-1)
Date: 29 Dec 92 01:01:20 GMT
Distribution: bionet
Checksum: 52742 6

LOCUS       MUSICAM1B    2545 bp ss-mRNA            ROD       04-DEC-1992
DEFINITION  Mouse (clone lambda-c5e) intercellular adhesion molecule 1 (ICAM-1)
            mRNA, complete cds.
ACCESSION   M31585
KEYWORDS    intercellular adhesion molecule 1.
SOURCE      Mus musculus cDNA to mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Siu,G., Hedrick,S.M. and Brian,A.A.
  TITLE     Isolation of the murine intercellular adhesion molecule 1 (ICAM-1)
            gene: ICAM-1 enhances antigen-specific T cell activation
  JOURNAL   J. Immunol. 143, 3813-3820 (1989)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            <1..2545
                     /note="ICAM-1 mRNA"
     sig_peptide     59..139
                     /codon_start=1
                     /note="intercellular adhesion molecule 1 signal peptide"
     mat_peptide     140..1669
                     /codon_start=1
                     /note="intercellular adhesion molecule 1"
     CDS             59..1671
                     /partial
                     /note="intercellular adhesion molecule 1 precursor"
                     /codon_start=1
                     /translation="MASTRAKPTLPLLLALVTVVIPGPGDAQVSIHPREAFLPQGGSV
                     QVNCSSSCKEDLSLGLETQWLKDELESGPNWKLFELSEIGEDSSPLCFENCGTVQSSA
                     SATITVYSFPESVELRPLPAWQQVGKDLTLRCHVDGGAPRTQLSAVLLRGEEILSRQP
                     VGGHPKDPKEITFTVLASRGDHGANFSCRTELDLRPQGLALFSNVSEARSLRTFDLPA
                     TIPKLDTPDLLEVGTQQKLFCSLEALFPASEARIYLELGGQMPTQESTNSSDSVSATA
                     LVEVTEEFDRTLPLRCVLELADQILETQRTLTVYNFSAPVLTLSQLEVSEGSQVTVKC
                     EAHSGSKVVLLSGVEPRPPTPQVQFTLNASSEDHKRSFFCSAALEVAGKFLFKNQTLE
                     LHVLYGPRLDETDCLGNWTWQEGSQQTLKCQAWGNPSPKMTCRRKADGALLPIGVVKS
                     VKQEMNGTYVCHAFSSHGNVTRNVYLTVLYHSQNNWTIIILVPVLLVIVGLVMAASYV
                     YNRQRKIRIYKLQKAQEEAIKLKGQAPPP"
BASE COUNT      583 a    704 c    700 g    558 t
ORIGIN      1 bp upstream of EcoRI site.
        1 gaattccggg tgcaggtagc agcggagctc agcactagca ctttgccctg gccctgcaat
       61 ggcttcaacc cgtgccaagc ccacgctacc tctgctcctg gccctggtca ccgttgtgat
      121 ccctgggcct ggtgatgctc aggtatccat ccatcccaga gaagccttcc tgccccaggg
      181 tgggtccgtg caggtgaact gttcttcctc atgcaaggag gacctcagcc tgggcttgga
      241 gactcagtgg ctgaaagatg agctcgagag tggacccaac tggaagctgt ttgagctgag
      301 cgagatcggg gaggacagca gtccgctgtg ctttgagaac tgtggcaccg tgcagtcgtc
      361 cgcttccgct accatcaccg tgtattcgtt tccggagagt gtggagctga gacctctgcc
      421 agcctggcag caagtaggca aggacctcac cctgcgctgc cacgtggatg gtggagcacc
      481 gcggacccag ctctcagcag tgctgctccg tggggaggag atactgagcc gccagccagt
      541 gggtgggcac cccaaggacc ccaaggagat cacattcacg gtgctggcta gcagagggga
      601 ccacggagcc aatttctcat gccgcacaga actggatctc aggccgcaag ggctggcatt
      661 gttctctaat gtctccgagg ccaggagcct ccggactttc gatcttccag ctaccatccc
      721 aaagctcgac acccctgacc tcctggaggt gggcacccag cagaagttgt tttgctccct
      781 ggaagccctg tttcctgcct ctgaagctcg gatatacctg gagctgggag gccagatgcc
      841 gacccaggag agcacaaaca gcagtgactc tgtgtcagcc actgccttgg tagaggtgac
      901 tgaggagttc gacagaaccc tgccgctgcg ctgcgttttg gagctagcgg accagatcct
      961 ggagacgcag aggaccttaa cagtctacaa cttttcagct cctgtcctga ccctgagcca
     1021 gctggaggtc tcggaaggga gccaagtaac tgtgaagtgt gaagcccaca gtgggtcgaa
     1081 ggtggttctt ctgagcggcg tcgagcctag gccacccacc ccgcaagtcc aattcacact
     1141 gaatgccagc tcggaggatc acaaacgaag cttcttttgc tctgccgctc tggaggtggc
     1201 gggaaagttc ctgtttaaaa accagaccct ggaactgcac gtgctgtatg gtcctcggct
     1261 ggacgagacg gactgcttgg ggaactggac ctggcaagag gggtctcagc agactctgaa
     1321 atgccaggcc tgggggaacc catctcctaa gatgacctgc agacggaagg cagatggtgc
     1381 cctgctgccc atcggggtgg tgaagtctgt caaacaggag atgaatggta catacgtgtg
     1441 ccatgccttt agctcccatg ggaatgtcac caggaatgtg tacctgacag tactgtacca
     1501 ctctcaaaat aactggacta taatcattct ggtgccagta ctgctggtca ttgtgggcct
     1561 cgtgatggca gcctcttatg tttataaccg ccagagaaag atcaggatat acaagttaca
     1621 gaaggctcag gaggaggcca taaaactcaa gggacaagcc ccacctccct gagcctgctg
     1681 gatgagactc ctgcctggac cccctgcagg gcaacagctg ctgctgcttt tgaacagaat
     1741 ggtagacagc atttaccctc agccacttcc tctggctgtc acagaacagg atggtggcct
     1801 gggggatgca cacttgtagc ctcagagcta agaggactcg gtggatggag caagactgtg
     1861 aacacgtgtg acccggaccc acctacacag cccggtggac ccttcagcca agaaacgctg
     1921 acttcattct ctattgcccc tgctgagggg ctcctgccta aggaagacat gatatccagt
     1981 agacacaagc aagaagacca cacttccccc gacacaggaa agctgagaca ttgtcccaac
     2041 tcttcttgat gtatttatta atttagagtt ttaccagcta tttattgagt accctgtata
     2101 tagtagatca gtgaggaggt gaatgtataa gttatggcct ggaccctgct gcagatgctg
     2161 tgagagtctg gggaaagatc acatgggtcg agggtttctc tactggtcag gatgcttttc
     2221 tcatataagg gtcgactttt ttcaccagtc acataaacac tatgtggact ggcagtggtt
     2281 ctctgcttcc tccacatcct ggagcgtccc agcacctccc cacctacttt tgttcccaat
     2341 gtcagccacc atgccttagc agctgaacaa tcgagcctca tgctcatgaa atcatggtcc
     2401 caggcggctc cacctcaaag agaaagcctg gaaggaaatg ttccaactcc ttagaagggt
     2461 cgtgcaagag ctgctgtggg agggtaagca cccctcccag cacagaaacc tttcctttga
     2521 atcaataaag ttttatgtct tcctg
//