From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Drosophila melanogaster suppressor of sable gene, complete cds.
Date: 24 Jul 92 10:06:09 GMT
Distribution: bionet
Checksum: 56203    16

LOCUS       DROSUSG      8493 bp ds-DNA             INV       24-JUL-1992
DEFINITION  Drosophila melanogaster suppressor of sable gene, complete cds.
ACCESSION   M57889
KEYWORDS    suppressor gene; suppressor of sable.
SOURCE      Drosophila melanogaster Oregon R P2, DNA and mRNA, clone
            lambda4su(s)+.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Voelker,R.A., Gibson,W., Graves,J.P., Sterling,J.F. and
            Eisenberg,M.T.
  TITLE     The Drosophila suppressor of sable gene encodes a polypeptide with
            regions similar to those of RNA-binding proteins
  JOURNAL   Mol. Cell. Biol. 11, 894-905 (1991)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     mRNA            join(415..807,2861..3248,3309..3544,4248..5545,5606..5730,
                     5825..8277)
                     /product="su(s) protein"
                     /gene="suppressor of sable"
     mRNA            join(415..807,2861..3248,3309..3544,4248..5545,5606..5730,
                     5825..8279)
                     /product="su(s) protein"
                     /gene="suppressor of sable"
     CDS             join(2975..3248,3309..3544,4248..5545,5606..5730,
                     5825..7860)
                     /product="su(s) protein"
                     /gene="suppressor of sable"
                     /codon_start=1
                     /translation="MSVALADEPLIDLEEDLEDGEIDDDEEDEQQSSKIQVQKKTFVG
                     DDDVQFVGVEAKNQNDDEDVVYVGPSTDAVCLQNSNSTKSKKPRPLEDDHASSIELAI
                     ANALKKKGIEPPMPRMRSSNQDTSDQSLEGSGEGLATANPLLQSTRSSRRRKRKKERE
                     REQKKDKEQQNRSRRDENDVSVVPGGVEDMDEYEMMNVRGGSPPPGGAAPPLSSCGQR
                     FSGADWDMDDGSAATGAAGLGAGGGGGYNSHSSYDSYSDEETNGPGLMNQRRRTRRDN
                     EKEHQRGVNNRKRRDRDRLEGGLAGSGSKRNRRDSGEGGGGGQEKMGGSNRVEPRKLE
                     LCKFYLMDCCAKRDKCSYMHKEFPCKYYYLGMDCYAGDDCLFYHGEPLSEQLRNVLLK
                     HMETAPKEILGDFKRISRDIAIVQMTRRHEQLCDQLNRENTWNSIGCGLMGKRQDHQM
                     QQQQQQLQHQQLQQQQEQQQTQQQAAADGGGCIPSLLDMVINPPLSENKRKSRWTEKM
                     GAKAAAGAAGSSERDSTSPDAKPLPPHLDLANLSHVLSAENMAKLNKLGITNLEQMLQ
                     VPFGQLTEAGLTLVEIGEIQRKAEDAKPQTQAELESSTPPSKRETEANNSNSKSNGLI
                     MVDYTQYLKDAHVSFSGNDPLDDDRDDDEQLIIDDGNDSTAEEDQQPKKAKAPPAATH
                     ESSTEEAPLPSVFDLPSFMNNMLGQGSSARQLLPASANQENAHLPGGDQSTHKSAPIG
                     GGTSTNVLGRILFGDKQSDPEARAAFYRDIIRNPFKAHSGDGDVDSSNENSNSNSHSL
                     TPTPTPEPGSQSPKPEDHDQDMPELPVIAPALPPTTPSLYVRRSMYDFDPVKEQEHGR
                     QELLTEEKEQYQRDTDMRLPFEPMKHYMPATEIDAAIFSHTPIRWQLHEVTIEESSYA
                     QIRASALHKEQRELRDPRMRRILGLPETPDNSGPLGSVPIMGPSSFSVDNIARCATTI
                     ASPDLETAVRDSTPSSPPPSVVNLPSMSVPPPSMRVPPPNIQVEKPTVRTDPRRDPRR
                     AVLQAPTKGASTANTTAPNASGGSKQISEIRSLLQVSNWYNNLGTNNKIMVNQQLALV
                     FTELKKFHQLPNDAPKIFDVSFIVNNTTLQQIFAKLFIFVDDNGEVVQIPEEPNGNGA
                     ALGGGGDSGGGVGGGGGGGGVVLPNLSQPPPNLSQMLRLPPPNIRMLRMSGMMMQMGN
                     VGPPFNQPPPRGGLMGMPPNGNGLNQGVGNLGGLGQLGINQGGGPVPNGNPFNPFGGN
                     NGGGAGVMNNMNSMGNMGMGFNNFNNNGGRGGHFPGGGSGGNGNGNNRNQRGGNHRNR
                     NI"
     exon            415..807
                     /number=1
                     /gene="suppressor of sable"
     intron          808..2860
                     /number=1
                     /gene="suppressor of sable"
     exon            2861..3248
                     /number=2
                     /gene="suppressor of sable"
     intron          3249..3308
                     /number=2
                     /gene="suppressor of sable"
     exon            3309..3544
                     /number=3
                     /gene="suppressor of sable"
     intron          3545..4247
                     /number=3
                     /gene="suppressor of sable"
     exon            4248..5545
                     /number=4
                     /gene="suppressor of sable"
     intron          5546..5605
                     /number=4
                     /gene="suppressor of sable"
     exon            5606..5730
                     /number=5
                     /gene="suppressor of sable"
     intron          5731..5824
                     /number=5
                     /gene="suppressor of sable"
     exon            5825..8277
                     /number=6
                     /note="alternative"
                     /gene="suppressor of sable"
     exon            5825..8279
                     /number=6
                     /note="alternative"
                     /gene="suppressor of sable"
BASE COUNT     2453 a   1999 c   1958 g   2083 t
ORIGIN      Chromosome X.
        1 gatccggcca tggcgatcgg gagtatacaa aaatgtttca ctttaggaaa tggccgataa
       61 attgcactcg ctgacatccg atagccgtgg cctgaagagc ttccaccgat cgatatcgat
      121 aaatggatat gttttctgca atagcgaaag atcggggtgc tacctattaa ttatacttaa
      181 gaaacagatg atgtagtttt ttgatataga agtttaacaa ccggttcaac aatcggttaa
      241 tatttaaaaa tgtcgcagcc agcgagcctt tagctttaaa agtaagcttg cgttcacggt
      301 ttttggggaa ataccaaata tactaggtaa aaacatcgat taactaatat catccaacac
      361 gacgatatgt tctttgcgaa aaatatcgat gtactggtat ttttatgttt ccacacctct
      421 agttcgttta agtcgatctg ttgaactgtt aacaacacaa ctcctgaata ttatgttttg
      481 gacgaaaagt tttattaatt taatgttttt gtatattgta ttctgtccat gagcgtaaca
      541 gagacagaca gagagaaagg gacagatact gagatacggg gccctcaggc agagaaagag
      601 ggcgaaagca agctacaagc gggtgcgagc gagagcgcgc gcttgcctca cgcacatata
      661 tataaatctg tacatacata tagtatcaga agaaaaaact aaagccgcta ttcgatttac
      721 gaaaactggc gaaaaattcg acgatttgtc tcgtacctat ctatgtacct cacaaccact
      781 tcgtcatcaa atacgtataa gtcagatgta tgtcaaacat atatatacat atgcatgtat
      841 atacacatct atgtgaggcc actgctatat cccatacatg tatgcctcta tatatatgta
      901 tatatttatc cacctactgt accacttcca cattatgtaa gcagcgacgc aaacaaaaca
      961 ctaaagcaga aaatccgaaa agcaaaatgc gaaatgcaaa acaacgaacc aacaaaatcc
     1021 catctataaa ccgaaaaccg aacagcaatg ttataacaaa taccgaaaag ttgttaatgt
     1081 tccacaaaaa agcataaagc agtcacgcta agagagtaag atcgaacaaa tgaaatgttt
     1141 gtatggcata agtagttccc agatttttgt atgtacttca atgcatatgc atgtgtgcgt
     1201 atgcatgtat gtatgtatgt ttctcggggc catgtctccc cacgcccacg tacgtgggtg
     1261 ctagaaaggg acagatggtg caaatttttt aaattgcata cacttgattt tggaacgcca
     1321 gccaaacaaa aagataaatt gcgtgctttt cttttgctgt tcgtatgtac gtacatatgc
     1381 aagtggaaac tgcgcagcag ggaagccaca cgcatgaacg ccttccattt acagagcatt
     1441 caaacaaatc gtaccgaaaa ccaaacaaaa actttcacct caagtgtaac aattatattc
     1501 aaattcgctt tgaagtcgct gtaaaatata tgtatgtatg tataaacaaa gacaaaaaca
     1561 ttttgcctcg cagtcgacac acacacgcgc actcgcactg cacgcctcgg ctgtgtgtgt
     1621 gtatgccctg cttagatcat gagtgtgcga gcgagtcgac atgcttggca atcgcgagtc
     1681 agaactaaac acgcgctcta tatgcacgtg tgtgagacgc attggatttt gttattttca
     1741 tcaatcgcaa tgattccgtc catcagctac atccaaatat atacacgcat ccgcgccata
     1801 tgtacaatgc tacgagcatt tacatacaca tgtacatatg cgcgtgtggc tcataacggt
     1861 tcactccgct tacgcacaat aataaaggca aacgcctacg acttccccat tgttcctagg
     1921 ctcaatggaa agccactccg ttgctttcga ctttcgcttt tcggattctg gaatttgttt
     1981 cgctgtccaa aactacgtat aactgaatct ttatgttaag ccaattgtaa aaagtgtatt
     2041 ttcctttctc gttctctcca cacaacaaat gtgctagcgc aactttgttg atcactttta
     2101 ttttatactg gaagcatgtc caggacccat accctttaat tcatcaaact gatttgctta
     2161 ttattttgtt gctgcacttt ggaactagct aagtgccagg ctaaacctaa gcgatccgat
     2221 cccacttaaa ccaaccaaca aagagcaatc caaccattgt cagcgaaaag tgctcaaact
     2281 ttccgagtgc tgagataagg aagggtgccc aaaacattca tcgcagccat gctgcccacg
     2341 ctacaaagtg actctgactg aatgcatcag gatcgtatga tccgggtggt ctatcttaag
     2401 tcaatagttt ctgtcgctag tacttggacg tgccttctga atccgtagtc atttgtgata
     2461 ccagccattt tatattgtat ttacctcaaa aacattaatg tagcatttat tcaagcaacg
     2521 cttgatttta gtgttaacca attcctttca tttgtgttca aaattttgac cgccaatggg
     2581 gtgattcaaa taatccccga atgattttgg aaaaaaagaa taaggggcat taaactacat
     2641 ttattaattc gtttttattc acttagaagc gtattatggt acattccacc tttttagtta
     2701 atactagcag ttgctttatt ttaagatacc attttatatt gtaattggac gttaagacaa
     2761 attataagac gtccttatat atgattagat tgggaatttg accttaaaac atatttatgc
     2821 atccatatat ggtattcaaa atccgatccc ttatcaacag cttttccaaa taccaaacac
     2881 ttaagagtgc agcaacagaa gagggaggcc acttttttta agggcaccaa ttattccaat
     2941 ctcatcctgt gagagattag ctgccaaatc gataatgtct gtcgctttag cggatgaacc
     3001 cttaattgac ttggaggagg atttagagga cggcgagatc gacgacgatg aggaggacga
     3061 gcagcaatct tcaaaaatcc aagtccaaaa gaagactttc gtaggggacg acgatgtgca
     3121 gtttgtgggt gtcgaggcta agaaccaaaa tgacgacgaa gatgtcgttt acgtgggacc
     3181 atcgacagat gccgtttgcc tccaaaacag caacagcacc aagtcaaaaa agcctcgccc
     3241 attagaaggt gaaagctcat tcagttgttt cattgattct tcttgtttaa tctggatgta
     3301 ttccctagat gaccatgcta gcagcattga gttggcgatt gccaatgccc tcaagaagaa
     3361 gggcatagag cccccaatgc cccgcatgcg ttcgtctaac caggatacga gcgatcagtc
     3421 tttggaggga tccggggagg gactggctac cgccaatccc cttcttcagt caactcgcag
     3481 cagcaggcga aggaaacgca agaaagaacg tgagcgcgag cagaagaaag acaaggagca
     3541 gcaggtgagg ccatcacatt atgtccaaat gcaactatta gatacccatt agctgacaaa
     3601 tgcagtatac ccttctgctc caggagcaag atttatatag ttgtagctag ccttcgattg
     3661 gcacttatga aatgattttt accatattta cctttttaaa tagaacattg atcttgggtg
     3721 ttacatggaa gcggttaacc cagccagcgt gaccaagttc cacgaccaat tgttttgtgt
     3781 tccgacccaa ctccgcgctt ctcctgcact taatttatca ttagccatcg ggattagtat
     3841 tgcatggctc gttcagcttg tttcaacaca ttgggtcagt gtacaaggca gggccaagta
     3901 tagggatctt aggccaagta tagggaatag gagcagaaaa ttaaatctga tatgacatta
     3961 cagtacagta ttctttatat cagtaccgcg aacgcagcaa atatccatgt ggaatgtaac
     4021 acgtctgctg ttcttatagg ggataccgag actttgctgg ggttcctcgc caggatgtcc
     4081 atcccgtgaa ttctagaatt atattttgtg gtttaagtat gtacgccgct ttgttatccc
     4141 cgcagaaagt ttcattaagg gattttagta atagttaaaa aggttatatg aacacacaca
     4201 tgttttctta ttgaaactcc tattgacttt atcttaatcc tttccagaac cgttcccgac
     4261 gtgacgagaa cgacgtgtct gtggtgccag gcggcgttga ggacatggac gaatatgaga
     4321 tgatgaacgt acgtggcggc agcccgccac caggaggagc ggcaccaccc ctttccagct
     4381 gcggtcagcg gtttagtggt gccgattggg acatggacga cgggtcagcc gcaaccggag
     4441 cagctggtct tggagcggga ggcggagggg gttacaactc acacagcagc tatgattcct
     4501 actccgatga ggagacaaat gggcccgggc taatgaatca acgccgtcgg acccgaaggg
     4561 ataacgaaaa ggagcaccag cgtggcgtga ataatcgcaa gcgcagggat cgcgatcgcc
     4621 ttgaaggcgg gttagcggga agcggctcca agcgaaatcg ccgtgattct ggcgaaggag
     4681 gcggcggtgg acaggaaaag atgggcggca gcaatcgcgt tgagccccgc aagctggagc
     4741 tgtgcaagtt ctatctaatg gactgctgtg ccaagcggga caagtgctcc tacatgcaca
     4801 aagagtttcc ctgtaagtac tactacctgg ggatggattg ctatgcaggc gacgattgcc
     4861 tcttttacca cggcgaaccg ctgtccgagc agctccgcaa cgttctgctg aaacacatgg
     4921 agacggctcc gaaggagatc cttggtgatt tcaagcgaat atccagagac attgccattg
     4981 tgcagatgac acggcggcac gagcagctgt gcgaccaatt gaatcgggag aacacgtgga
     5041 attcgattgg ctgcggctta atgggcaagc ggcaggacca tcaaatgcaa caacagcagc
     5101 aacagcttca gcatcaacag cttcagcagc agcaggagca acagcagacg caacagcagg
     5161 cggctgcgga tggcggcggc tgcattcctt cacttttgga catggtcatc aatccaccac
     5221 tttcagaaaa taagcgcaag tcccgctgga ccgaaaagat gggtgccaag gcagcagctg
     5281 gagcagcagg ttcttcagaa agggatagca catcgccgga cgccaagcca ctaccaccac
     5341 acttggactt ggctaatctc agtcacgtct taagtgctga aaacatggcc aagctaaata
     5401 agttgggtat tacgaatctg gagcagatgc ttcaagtgcc gtttggccag ttgaccgagg
     5461 ctggcctaac tctggtcgag atcggtgaga ttcagcgcaa agccgaggac gccaagccgc
     5521 aaacccaagc tgaattggaa agcaggtgag ctaatcaatg caaaacaaat tacaatttcc
     5581 ttattttaat atatatgttc actagcactc ctccttcaaa gcgggaaacg gaggccaaca
     5641 atagtaactc gaagagcaac ggactcatca tggtggacta cacgcagtac ctcaaggatg
     5701 cacatgtcag cttttcgggt aacgatccgc gtgagtagat ggcaccattt gaacttaatc
     5761 tatttctttt cattctcttc acggcgttat gaataatttt attaacttgc gaatttcatt
     5821 ccagtggacg acgatcggga tgacgacgaa caactgatca tagacgatgg caacgattcc
     5881 accgccgaag aggaccagca acctaagaaa gccaaggcac cgccagccgc cacccatgaa
     5941 tcaagcacag aggaggcacc cttgccttct gttttcgact tgccgagctt catgaacaac
     6001 atgctgggtc agggatcctc agcgaggcag ttgctgcccg caagtgccaa tcaggagaat
     6061 gcgcatttgc ctggaggaga tcaatcgaca cataaatccg cgcccatcgg cggaggcacc
     6121 tcaaccaacg tgcttggccg gattctgttc ggcgacaaac aatctgaccc cgaggctaga
     6181 gcagctttct atcgcgacat aatacgcaat cccttcaagg ctcacagtgg cgatggcgac
     6241 gtggactcca gcaatgagaa ctcaaattcc aattcgcatt ccctgacgcc aactcccacg
     6301 ccagagccgg gatcccaatc ccccaagccg gaggaccacg atcaggatat gccggaattg
     6361 cctgtcattg caccagcgtt gccgccgaca actccttcgc tctatgtacg tcgttccatg
     6421 tatgacttcg atcccgtcaa agagcaagag cacgggcgac aggagcttct tacggaggag
     6481 aaggaacagt accagcgtga taccgacatg cgactgccgt tcgagccgat gaaacactat
     6541 atgcctgcca ccgagatcga cgcggcgatc ttctcgcaca ctccgatacg ctggcagctg
     6601 catgaagtaa ccatagagga gagcagctat gctcagatta gggccagtgc tctgcacaag
     6661 gagcagcggg agctacgcga tcctcgaatg cgtcggattc tcggccttcc ggaaacgcct
     6721 gataacagtg gacccttggg ctccgtgccc attatgggcc caagctcctt ttcggtcgac
     6781 aacattgcgc gttgcgctac gaccatcgct tccccagatt tggagaccgc cgttcgtgat
     6841 tccaccccca gttcaccgcc cccgtccgtg gtaaacctac cgtcaatgag tgtgccaccg
     6901 ccgtcgatga gggtaccacc tccgaacata caggtggaaa agccaactgt gcggacagat
     6961 ccacgtcgcg atcccaggag agccgttctg caggctccaa ctaaaggtgc tagtacggca
     7021 aacaccacag cacccaatgc ctctggtggc agcaagcaaa tctcggaaat ccgaagcctg
     7081 ctgcaggttt ccaactggta caacaatctc ggcaccaaca ataagattat ggtgaaccaa
     7141 cagctcgccc tggtctttac cgagctcaag aagttccatc agctgccgaa tgatgctccg
     7201 aaaattttcg atgtcagctt tatagtgaac aacacaacgt tgcagcagat ctttgccaag
     7261 ctctttatct ttgtagatga caatggcgag gtggtgcaga ttcccgagga gcccaacggt
     7321 aatggtgctg ctcttggtgg cggcggagat tctggaggcg gagtaggagg aggaggagga
     7381 ggaggaggag tagtgcttcc caatctatcg caacccccac caaatctgag ccaaatgtta
     7441 aggctaccgc caccgaacat acgaatgctt cgcatgtcgg gaatgatgat gcaaatgggc
     7501 aacgtgggac cccctttcaa tcagccaccg ccacgcggag gattgatggg aatgcctccg
     7561 aatggcaatg gattaaacca gggcgttggc aatctgggag gacttggcca gttggggata
     7621 aaccaaggag gaggacctgt gcccaatggc aatcccttca acccatttgg tgggaacaat
     7681 gggggaggag ctggcgtcat gaacaacatg aattcaatgg gcaacatggg catgggcttc
     7741 aataacttca acaataatgg cggcagagga gggcactttc cgggcggagg atcaggcgga
     7801 aacggcaacg gaaacaatcg caaccagcga ggcggcaacc accgaaaccg caacatttaa
     7861 aggcccatgc gttgcgaaaa cacaaacgca aaaggagccc ttttgcccca atgatcttaa
     7921 agcgatgcta tgccacatga ccctttcccc caaccatacc atacgtcgtg gaaaactcgt
     7981 ggttttccgc gcaccttccc cgaaaatcca ggcatgactc cttgtaaatg tattttattc
     8041 ccgaatcccc attattgtca ctattttttt cgctaggtgt aaggatctta ttagctatac
     8101 gagtagtaaa gagtaaataa caaaacaatc cggagtaaga acgaaaagtg aagcagaatg
     8161 gtatgcgcag ccctttttaa caaacttttt taaattatat aggataattt gttcaatagc
     8221 gcgagtacta cattgattaa ctagacgtac gaactcaaaa taaatgacat cttttaagta
     8281 atgtgccatg cttaggttgc tgggccgtcc cggaggagca gaaagaaatg aatagctttt
     8341 gaaagcgcgc gaaactacac ctaaactctt tagaaagctt ttgcgtactt atcgatgcta
     8401 aattctgaat tggcttctcg accattttta atttagttcc tacaaggtat atgtttacgt
     8461 ttacgtttaa attatgacat cttctgcgaa ttc
//