From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus (clones PTZ 18r 5.3 and PTZ 18r 4.1)
Date: 28 Dec 92 21:45:19 GMT
Distribution: bionet
Checksum: 44666 4

LOCUS       RATPDGFAX    1009 bp ss-mRNA            ROD       02-DEC-1992
DEFINITION  Rattus norvegicus (clones PTZ 18r 5.3 and PTZ 18r 4.1)
            platelet-derived growth factor A-chain (PDGF A) mRNA, complete cds.
ACCESSION   L06894
KEYWORDS    platelet-derived growth factor A-chain.
SOURCE      Rattus norvegicus (strain Lewis) (library: lambda-gt11 of W.
            Stoffel, Institut fur Biochemie, Universitat zu Koln) postnatal day
            21 brain cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (sites)
  AUTHORS   Katayose,D., Ohe,M., Yamauchi,K., Shibahara,S. and Takishima,T.
  TITLE     Expression of Platelet-derived Growth Factor ( PDGF ) -A and -B
            Chains in the Rat Lungs with Hypoxic Pulmonary Hypertension.
  JOURNAL   Unpublished (1991)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1009)
  AUTHORS   Pollock,R.A. and Richardson,W.D.
  TITLE     Investigations into the function of structural isoforms of the
            platelet derived growth factor A-chain
  JOURNAL   Theses-University College London, London, England 1, 105-121 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     conflict        replace(88,"g")
                     /citation=[1]
                     /note="g in conflict with accession #D10106"
     conflict        replace(380..382,"ag")
                     /citation=[1]
                     /note="effects frame shift relative to previously reported
                     sequence D10106"
     conflict        replace(465..466,"ccc")
                     /citation=[1]
                     /note="return to the same frame as previously reported
                     sequence D10106"
     conflict        replace(777..779,"ga")
                     /citation=[1]
     conflict        replace(893..895,"ga")
                     /citation=[1]
     CDS             131..721
                     /gene="PDGF A"
                     /product="platelet-derived growth factor A-chain"
                     /codon_start=1
                     /translation="MRTWACLLLLGCGYLAHALAEEAEIPRELIERLARSQIHSIRDL
                     QRLLEIDSVGAEDALETNLRAHGSHTVKHVPEKRPVPIRRKRSIEEAIPAVCKTRTVI
                     YEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRK
                     KPKLKEVQVRLEEHLECACATSNLNPDHREEETDVR"
BASE COUNT      255 a    277 c    296 g    181 t
ORIGIN      
        1 ggaattcggc actgcagtgg cggccgggcc cgatctggcc cgcgagaccc ctgagcgctt
       61 ccgaggagcc cggctggatc tcccgccccg gcctcgcctc cctgccgagc ttccagcgcc
      121 tcgggacgcg atgaggacct gggcttgcct gctgctcctc ggctgcggat acctcgccca
      181 tgccctggcc gaggaagccg agataccccg ggagttgatc gagcgactgg ctcgaagtca
      241 gatccacagc atccgggacc tccagcgact cttggagata gactccgtag gggctgagga
      301 tgccttggag acaaacctga gagcccatgg gtcccacact gttaagcatg tgccggagaa
      361 gcggcctgtg cccatccgca ggaagagaag tattgaggaa gccattcccg cagtttgcaa
      421 gaccaggacg gtcatttacg agatacctcg gagccaggtg gaccccacat cggccaactt
      481 cttgatctgg cccccatgtg tggaggtgaa gcgctgcact ggctgctgta acaccagcag
      541 cgtcaagtgc cagccctcaa gggtccacca ccgcagtgtc aaggtggcca aagtggagta
      601 tgtcaggaag aagccaaaat tgaaagaggt ccaggtgagg ttagaggagc acctggagtg
      661 cgcatgcgcg acctccaacc tgaacccaga ccatcgggag gaggagacgg atgtgaggtg
      721 agatgagctg gctgccctct cccgggacac ggatgtacgt ggcgtgtgac attcctgaac
      781 atactatgta tggtgcttca ttgccaatgt gcgtgcagtc tttgttctcc tccgtgaaaa
      841 actgtgtccg aggacaaaga gacagtgtcc gtttgttcag tgtgacatca aagcaagtac
      901 tgtagcactc ggagagacag tgagaaagct tccttgtcac agagagcgaa aacaaaacca
      961 caaaaaagaa aaaaaaaaaa aacaaaaaat taaaaaaaaa ccgaattcg
//