From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens HAP1 gene for AP endonuclease 1
Date: 24 Jul 92 10:06:39 GMT
Distribution: bionet
Checksum: 64366     6

LOCUS       HUMHAP1      2957 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  H.sapiens HAP1 gene for AP endonuclease 1
ACCESSION   X66133
KEYWORDS    HAP1 gene; endonuclease I.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2957)
  AUTHORS   Robson,C.N.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: clone_library=Lorist;
            From EMBL    entry HSHAP1;  dated 16-JUN-1992.
FEATURES             Location/Qualifiers
     exon            <587..587
                     /number=1
     CDS             join(838..895,1106..1293,1859..2051,2182..2699)
                     /product="AP endonuclease 1"
                     /gene="HAP1"
                     /codon_start=1
                     /translation="MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPAL
                     YEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSEN
                     KLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVA
                     EFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEI
                     DLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSK
                     NVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL"
     intron          588..769
                     /number=1
     exon            770..895
                     /number=2
     intron          896..1105
                     /number=2
     exon            1106..1293
                     /number=3
     intron          1294..1858
                     /number=3
     exon            1859..2051
                     /number=4
     intron          2052..2181
                     /number=4
     exon            2182..>2699
                     /number=5
BASE COUNT      712 a    713 c    714 g    818 t
ORIGIN
        1 ctgcagatag cactgggaaa gacaccgcgg aactcccgcg agcgagaccc gccaaggccc
       61 ctccagggac ctgtcttcct aacgtccagg gagcccgagc caactcgcgc cttacattcg
      121 tatccgtttt cctatctctt tcccgtggtc agcccagcct tctccactgt ttttttcctc
      181 ttgcacagag ttagaatctt aagtcagtgt cacacaatgt gctgtgcatc tggcacaacg
      241 ataaacagcc gagggagggt tggggactaa gtgcctagag aattagagga gggaggcgag
      301 gctaagcgtc cgtcacgtgg tgtcagacag accaatcacg cgcattcttc ggccacgaca
      361 agcgcgcctc tgatcacgtg accaggtccg ctacccacgt gggggctcag cgtgcaccct
      421 tctttgtgct cgggttagga ggagctaggc tgccatcggg ccggtgcaga tacggggttg
      481 ctcttttgct cataagaggg gcttcgctgg cagtctgaac ggcaagcttg agtcaggacc
      541 cttaattaag atcctcaatt ggctggaggg cagatctcgc gagtagggta caaggcacta
      601 tgaaatgatc tagtttcgtg ggtgaggggc tgaagggcct atgatgcacg gaggcgggga
      661 aaggatttag agataacgtg gtttaaaggc gggacctggt gcggggacgc tccttgggag
      721 gagtcttctc ccagccttag ctggtttcat gatttctttg cgtctgtagg caacgcggta
      781 aaaatattgc ttcggtgggt gacgcggtac agctgcccaa gggcgttcgt aacgggaatg
      841 ccgaagcgtg ggaaaaaggg agcggtggcg gaagacgggg atgagctcag gacaggtaag
      901 ggaatgaaat cagcccttct tcctagaagc tgcggcgggg gtgtttgtca ttcccttgat
      961 gtacggtaag tacgggccga ctcatttttg caggggtttg tgaagaagtc gcaggaaccg
     1021 taggctttcg ttgggtctat agttaacgcc ggatcgcagt tggaaaccac cagctttttg
     1081 tcagtatata ttactcattt tatagagcca gaggccaaga agagtaagac ggccgcaaag
     1141 aaaaatgaca aagaggcagc aggagagggc ccagccctgt atgaggaccc cccagatcag
     1201 aaaacctcac ccagtggcaa acctgccaca ctcaagatct gctcttggaa tgtggatggg
     1261 cttcgagcct ggattaagaa gaaaggatta gatgtgagtg gaatttgagg gaaagagaca
     1321 ttttttagta ttgaatggtc ttagggttta gtcacccctt ttctccgttt agccttcagg
     1381 ctgttttatt tttctcctgc ccgtagtttt ctgtggggct tccccagtct tgccagttgt
     1441 atttcctaaa tgtctgttcc ttcacttcca ttgccatttt cttttttagt gttctctcct
     1501 cttcccagaa tgttgcaaaa acctcttcac tatacttcct ccattttatc ttcctgcatt
     1561 gcattccata tgaagcatgt cctccattcc attaaccata gcttaaaatc ttagcttgct
     1621 atccactgcc tatagaaaaa acacatctcc ttggcatagc atgtaagact ttcttacctc
     1681 tctatatttg ttttcattta tctagcttag aattgtttga atattgtgct gcttgactcg
     1741 aactccttag gccaagagac tgtttaaccc gtgcgtatct atgacttagc atatagatta
     1801 ttcaataaat gttctgctga attgataata cgttttccac ctttcttttc acttacagtg
     1861 ggtaaaggaa gaagccccag atatactgtg ccttcaagag accaaatgtt cagagaacaa
     1921 actaccagct gaacttcagg agctgcctgg actctctcat caatactggt cagctccttc
     1981 ggacaaggaa gggtacagtg gcgtgggcct gctttcccgc cagtgcccac tcaaagtttc
     2041 ttacggcata ggtgagaccc tattgatgcc taatgcctga actcttcaaa accaattgct
     2101 aattctctat ctctgcccca cctcttgatt gctttccctt ttcttatagt tttttatgct
     2161 aattctgttt catttctata ggcgatgagg agcatgatca ggaaggccgg gtgattgtgg
     2221 ctgaatttga ctcgtttgtg ctggtaacag catatgtacc taatgcaggc cgaggtctgg
     2281 tacgactgga gtaccggcag cgctgggatg aagcctttcg caagttcctg aagggcctgg
     2341 cttcccgaaa gccccttgtg ctgtgtggag acctcaatgt ggcacatgaa gaaattgacc
     2401 ttcgcaaccc caaggggaac aaaaagaatg ctggcttcac gccacaagag cgccaaggct
     2461 tcggggaatt actgcaggct gtgccactgg ctgacagctt taggcacctc taccccaaca
     2521 caccctatgc ctacaccttt tggacttata tgatgaatgc tcgatccaag aatgttggtt
     2581 ggcgccttga ttactttttg ttgtcccact ctctgttacc tgcattgtgt gacagcaaga
     2641 tccgttccaa ggccctcggc agtgatcact gtcctatcac cctataccta gcactgtgac
     2701 accaccccta aatcactttg agcctgggaa ataagccccc tcaactacca ttccttcttt
     2761 aaacactctt cagagaaatc tgcattctat ttctcatgta taaaactagg aatcctccaa
     2821 ccaggctcct gtgatagagt tcttttaagc ccaagatttt ttatttgagg gttttttgtt
     2881 ttttaaaaaa aaattgaaca aagactacta atgactttgt ttgaattatc cacatgaaaa
     2941 taaagagcca tagtttc
//