From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Lamprey vitellogenin mRNA, complete cds.
Date: 6 Nov 92 18:07:46 GMT
Distribution: bionet
Checksum: 64303 12

LOCUS       ICHVITGN     5976 bp ss-mRNA            VRT       28-OCT-1992
DEFINITION  Lamprey vitellogenin mRNA, complete cds.
ACCESSION   M88749
KEYWORDS    vitellogenin.
SOURCE      Ichthyomyzon unicuspus female adult liver cDNA to mRNA.
  ORGANISM  Ichthyomyzon unicuspus
            Eukaryota; Animalia; Chordata; Vertebrata; Agnatha;
            Petromyzoniformes; Petromyzonidae.
REFERENCE   1  (sites)
  AUTHORS   Meininger,T., Raag,R., Roderick,S. and Banaszak,L.J.
  TITLE     Preparation of single crystals of a yolk lipoprotein
  JOURNAL   J. Mol. Biol. 179, 759-764 (1984)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Raag,R., Appelt,K., Xuong,N.-H. and Banaszak,L.J.
  TITLE     Structure of the lamprey yolk lipid-protein complex
            lipovitellin-phosvitin at 2.8A resolution
  JOURNAL   J. Mol. Biol. 200, 553-569 (1988)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 5976)
  AUTHORS   Sharrock,W.J., Rosenwasser,T.A., Gould,J., Knott,J., Hussey,D.,
            Gordon,J.I. and Banaszak,L.J.
  TITLE     Sequence of lamprey vitellogenin. Implications for the lipovitellin
            crystal structure
  JOURNAL   J. Mol. Biol. 226, 903-907 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..83
                     /note="putative"
                     /partial
     sig_peptide     84..125
                     /codon_start=1
     mat_peptide     126..5552
                     /product="vitellogenin"
                     /codon_start=1
     3'UTR           5556..5976
                     /note="putative"
                     /partial
     CDS             84..5555
                     /evidence="EXPERIMENTAL"
                     /product="vitellogenin"
                     /codon_start=1
                     /translation="MWKLLLVALAFALADAQFQPGKVYRYSYDAFSISGLPEPGVNRA
                     GLSGEMKIEIHGHTHNQATLKITQVNLKYFLGPWPSDSFYPLTAGYDHFIQQLEVPVR
                     FDYSAGRIGDIYAPPQVTDTAVNIVRGILNLFQLSLKKNQQTFELQETGVEGICQTTY
                     VVQEGYRTNEMAVVKTKDLNNCDHKVYKTMGTAYAERCPTCQKMNKNLRSTAVYNYAI
                     FDEPSGYIIKSAHSEEIQQLSVFDIKEGNVVIESRQKLILEGIQSAPAASQAASLQNR
                     GGLMYKFPSSAITKMSSLFVTKGKNLESEIHTVLKHLVENNQLSVHEDAPAKFLRLTA
                     FLRNVDAGVLQSIWHKLHQQKDYRRWILDAVPAMATSEALLFLKRTLASEQLTSAEAT
                     QIVYSTLSNQQATRESLSYARELLHTSFIRNRPILRKTAVLGYGSLVFRYCANTVSCP
                     DELLQPLHDLLSQSSDRADEEEIVLALKALGNAGQPNSIKKIQRFLPGQGKSLDEYST
                     RVQAEAIMALRNIAKRDPRKVQEIVLPIFLNVAIKSELRIRSCIVFFESKPSVALVSM
                     VAVRLRREPNLQVASFVYSQMRSLSRSSNPEFRDVAAACSVAIKMLGSKLDRLGCRYS
                     KAVHVDTFNARTMAGVSADYFRINSPSGPLPRAVAAKIRGQGMGYASDIVEFGLRAEG
                     LQELLYRGSQEQDAYGTALDRQTLLRSGQARSHVSSIHDTLRKLSDWKSVPEERPLAS
                     GYVKVHGQEVVFAELDKKMMQRISQLWHSARSHHAAAQEQIRAVVSKLEQGMDVLLTK
                     GYVVSEVRYMQPVCIGIPMDLNLLVSGVTTNRANLHASFSQSLPADMKLADLLATNIE
                     LRVAATTSMSQHAVAIMGLTTDLAKAGMQTHYKTSAGLGVNGKIEMNARESNFKASLK
                     PFQQKTVVVLSTMESIVFVRDPSGSRILPVLPPKMTLDKGLISQQQQQPHHQQQPHQH
                     GQDQARAAYQRPWASHEFSPAEQKQIHDIMTARPVMRRKQHCSKSAALSSKVCFSARL
                     RNAAFIRNALLYKITGDYVSKVYVQPTSSKAQIQKVELELQAGPQAAEKVIRMVELVA
                     KASKKSKKNSTITEEGVGETIISQLKKILSSDKDKDAKKPPGSSSSSSSSSSSSSSSS
                     SSDKSGKKTPRQGSTVNLAAKRASKKQRGKDSSSSSSSSSSSSDSSKSPHKHGGAKRQ
                     HAGHGAPHLGPQSHSSSSSSSSSSSSSSASKSFSTVKPPMTRKPRPARSSSSSSSSDS
                     SSSSSSSSSSSSSSSSSSSSSSESKSLEWLAVKDVNQSAFYNFKYVPQRKPQTSRRHT
                     PASSSSSSSSSSSSSSSSSSSDSDMTVSAESFEKHSKPKVVIVLRAVRADGKQQGLQT
                     TLYYGLTSNGLPKAKIVAVELSDLSVWKLCAKFRLSAHMKAKAAIGWGKNCQQYRAML
                     EASTGNLQSHPAARVDIKWGRLPSSLQRAKNALLENKAPVIASKLEMEIMPKKNQKHQ
                     VSVILAAMTPRRMNIIVKLPKVTYFQQGILLPFTFPSPRFWDRPEGSQSDSLPAQIAS
                     AFSGIVQDPVASACELNEQSLTTFNGAFFNYDMPESCYHVLAQECSSRPPFIVLIKLD
                     SERRISLELQLDDKKVKIVSRNDIRVDGEKVPLRRLSQKNQYGFLVLDAGVHLLLKYK
                     DLRVSFNSSSVQVWVPSSLKGQTCGLCGRNDDELVTEMRMPNLEVAKDFTSFAHSWIA
                     PDETCGGACALSRQTVHKESTSVISGSRENCYSTEPIMRCPATCSASRSVPVSVAMHC
                     LPAESEAISLAMSEGRPFSLSGKSEDLVTEMEAHVSCVA"
BASE COUNT     1417 a   1866 c   1586 g   1107 t
ORIGIN      
        1 cccagctctc tcctctcttc ggactcctcc aggactcctc tcgcctacta ctgaaccgcc
       61 accgctcaac aaataccgca accatgtgga agctactcct cgtggctttg gcgtttgccc
      121 tagcagatgc gcagttccag ccggggaagg tttaccgcta ctcctacgac gccttctcca
      181 tctctgggct gcccgaacct ggcgtgaacc gcgcgggact cagtggcgag atgaagatcg
      241 agatccatgg gcacacgcac aatcaggcca ctctgaagat tacgcaggtg aacctcaagt
      301 atttcttagg accgtggcct tccgactcgt tctacccgtt gacagcgggg tacgaccact
      361 tcattcagca gctcgaggtg cccgtaaggt tcgactacag tgccggccgc atcggagaca
      421 tctacgctcc gccccaggtc accgacaccg cggtgaacat tgtcagggga atccttaacc
      481 tcttccagct gtccctcaag aagaaccagc agaccttcga gctccaggag accggcgtgg
      541 aaggtatctg ccagacgact tacgtcgtcc aagagggcta ccgcaccaac gagatggcgg
      601 tggtgaagac caaggacttg aacaattgcg accacaaggt ttacaagacg atgggaactg
      661 cctacgctga gcgctgcccg acctgccaaa agatgaacaa gaacctgcgc agcactgccg
      721 tgtacaacta cgccatcttc gacgagccct ccggttacat catcaagagc gcacactccg
      781 aagagatcca gcagctgagc gtgttcgaca tcaaagaagg gaacgtggtc attgaatcaa
      841 ggcaaaagct aatcctggag ggaatccaat ctgctccggc agccagccag gcagcttctc
      901 tgcagaaccg cggtggactc atgtacaaat tcccgtcgtc agccatcact aagatgtcgt
      961 ccctctttgt gaccaaggga aagaatctcg agtcagagat ccacactgta ctcaagcacc
     1021 tggtggagaa taaccagctc tccgtccacg aggacgcgcc cgccaagttc ctccgtctca
     1081 ccgccttcct tcgcaacgtg gacgcgggcg tcctccagtc aatctggcac aagctccacc
     1141 agcagaagga ctacaggcgc tggattttgg acgctgtccc agccatggcc acgtctgagg
     1201 cactgctctt cctgaagcgg acgctcgcca gcgagcagct gacctcggcc gaggccacgc
     1261 agatcgtcta cagcaccctg agcaatcagc aggccactcg cgaatcgctc agctacgcac
     1321 gggaattgct ccacaccagc ttcatcagga accgccccat actgcgcaag accgcggtgc
     1381 tggggtatgg ctctctcgtc ttccgctact gcgccaacac cgtctcctgc cccgatgagt
     1441 tactgcagcc gctccacgac ttgctgagcc agtcatcaga cagagccgac gaggaggaga
     1501 tcgtcctggc cctcaaggcc ttgggcaacg ccgggcaacc caacagcatc aagaagatcc
     1561 agaggttcct gccggggcag ggcaagtccc tggatgagta ctcgactcgg gtgcaggccg
     1621 aggccatcat ggccctgaga aacatcgcca agcgagaccc gcgcaaggtg caagagatcg
     1681 tgctgcccat cttcctgaac gtggccatca agtcggagct ccggatccgc tcctgcatcg
     1741 tcttcttcga gtcgaagccg tccgtggcgc tggttagcat ggtcgccgtg cgcctccgtc
     1801 gtgagcccaa cctgcaggtg gcgagtttcg tctactctca aatgcgctcg ctgtcccgga
     1861 gcagcaatcc cgagttcagg gacgttgccg cagcctgcag cgtggccatc aagatgctgg
     1921 gctccaagct ggatcgcctc ggatgccgct acagcaaggc cgtgcacgtg gacacgttta
     1981 acgcgaggac catggccggt gtctctgctg actacttcag gatcaactcc ccatccggcc
     2041 ctctgcctcg tgctgtggca gccaagatcc gcggccaggg catgggctac gctagcgaca
     2101 ttgtggagtt tggactgcgc gccgaaggtc tccaggagct gctgtacagg ggaagccaag
     2161 agcaggacgc ctacggcacg gccttggaca gacagacttt gctgcgtagc ggccaggcca
     2221 ggagccacgt gtccagcatc cacgacaccc tgcgcaagct gtcggactgg aagtcggtcc
     2281 ctgaagagag gccgcttgcc tcaggatacg tgaaggttca tgggcaggag gtggtgtttg
     2341 cagagcttga caagaaaatg atgcagcgaa tctcacagct gtggcacagc gcacggtcgc
     2401 accacgcggc ggcgcaggag cagatccgcg cggtagtgag caagctggag cagggcatgg
     2461 acgtgctcct caccaagggc tacgtcgtgt ccgaagttcg gtacatgcag cccgtgtgca
     2521 tcggcatccc catggacctc aacctcctgg tctccggagt gaccaccaac cgcgccaacc
     2581 ttcacgccag cttctcacaa tcgctgcccg cggacatgaa gctcgcagat ctcctcgcca
     2641 ccaacatcga gctgcgcgtg gccgcaacta ccagcatgtc ccagcatgcc gtggctatca
     2701 tgggactcac cacggatctg gccaaagccg ggatgcagac ccactacaag acgagtgcag
     2761 gcctcggggt caacggcaag attgagatga acgccaggga gagcaacttc aaggcgtcat
     2821 tgaagccctt ccagcagaaa accgtcgtgg tgctatcaac catggaatcc attgtgttcg
     2881 tgagagaccc ctccggcagc cgtatcttgc ccgtgctgcc cccgaagatg accttagaca
     2941 agggacttat atcccagcag cagcagcagc cacaccacca gcaacaacca caccagcacg
     3001 gccaggacca ggccagagcg gcctaccaac gcccatgggc gtcccacgag ttctcgccag
     3061 ccgagcagaa gcagatccac gacatcatga cggcgcgccc cgtgatgcgc aggaagcagc
     3121 actgctccaa gtcggcggcg ctctcctcta aggtgtgctt ctccgcccgg ctccgcaacg
     3181 ccgcgttcat ccgcaacgcg ctgctctaca agatcaccgg agactacgtc agcaaggtct
     3241 acgtccagcc cacgagcagc aaggctcaga tccaaaaggt ggagctcgag ttacaagccg
     3301 gaccccaggc agctgaaaag gtcatccgta tggtggaact ggtggccaag gcaagcaaga
     3361 agtcaaagaa aaactccacc atcacagagg agggtgttgg agaaacgatc atctcccagc
     3421 tcaagaagat cctcagcagt gacaaagaca aggatgctaa aaaaccaccc ggttcttcgt
     3481 cgtcatcttc atcatcgtca tcgtcgtcgt cgtcctcatc ctcatcagat aagtccggta
     3541 aaaagacgcc gcggcagggc agcaccgtga acctggctgc caagagggcc tccaagaagc
     3601 agcgcggaaa ggactccagc agctcgtcgt ccagctcgtc cagctcgtcg gacagctcca
     3661 agtcgcccca caagcacggc ggggcaaaga ggcagcacgc cggacacggc gccccgcacc
     3721 tgggacccca gtcgcattct tcgtccagta gcagcagtag cagcagtagc agcagcagcg
     3781 ccagcaagtc gttcagcacc gtcaagccgc ccatgaccag gaagccccgt cccgcccgca
     3841 gctcgagttc cagctccagc tccgactcca gctcaagctc cagctccagt tccagctcaa
     3901 gctccagcag cagtagcagc agcagcagca gcagcgagag caagagcctc gagtggctcg
     3961 cggtcaagga cgtgaatcag agcgcattct acaacttcaa atacgtcccc cagaggaagc
     4021 cccagacttc ccgcagacac actcctgcca gcagcagcag cagtagcagc agcagcagca
     4081 gcagcagcag cagctcctct tccagtgaca gcgacatgac tgtcagcgcc gaatcgtttg
     4141 agaagcactc gaagccgaag gtggtgatcg tgctgcgtgc ggtgcgcgcc gacggcaagc
     4201 agcagggcct gcagacgacc ttgtactacg gcctcacgtc caacgggctg cccaaggcaa
     4261 agatcgttgc tgtcgagctc agcgatctga gcgtgtggaa gttgtgcgcc aagttccgct
     4321 tgtccgccca catgaaggca aaggctgcca tcggctgggg aaagaactgc cagcagtacc
     4381 gcgccatgct ggaggcatcg actggcaacc tccagtcaca ccctgccgcg cgcgtggata
     4441 taaagtgggg ccgcctgccc agctccttgc agagagcgaa gaacgcactg ctcgagaaca
     4501 aagccccggt gattgcctcc aagctggaga tggaaatcat gccaaagaag aaccagaaac
     4561 atcaagtctc tgtcatcctc gcagccatga cccccaggag aatgaacatc atcgtgaaac
     4621 tccccaaggt cacttatttc cagcaaggca ttttgttgcc gttcaccttc ccctcaccaa
     4681 ggttctggga tcgtcccgaa ggatcccaat ccgacagtct tccagctcag atcgccagcg
     4741 ccttctcggg catcgtccaa gaccccgtcg cctctgcgtg cgagctgaat gaacaatccc
     4801 tgaccacgtt taacggcgcc ttcttcaact atgacatgcc cgagagttgc taccacgtgc
     4861 tggcgcagga atgcagttcc aggcctcctt tcatcgttct aatcaaactc gactccgaaa
     4921 gacgtatctc tcttgagctc cagctcgatg acaaaaaggt gaagattgtg agcaggaacg
     4981 acatcagagt cgatggtgaa aaggttccct tgcgccgtct ttcccaaaaa aatcaatatg
     5041 gttttctggt tctcgatgcc ggagtgcacc tgctgctcaa gtataaggat ctgagagtgt
     5101 cgttcaactc ctcatctgtt caggtgtggg tgccctcgtc gctgaaggga caaacgtgcg
     5161 gtctctgcgg ccgcaacgac gacgagctgg tgactgagat gcgcatgccc aacttggaag
     5221 tggccaaaga cttcacgagc tttgcgcact cctggattgc accggatgag acctgcggtg
     5281 gtgcctgcgc cctgagccgg cagaccgtgc acaaggagag cacctccgtc atcagcggtt
     5341 cccgcgagaa ctgctactcc accgagccca tcatgcgctg ccctgccacc tgctcagcct
     5401 cccgctccgt gccagtctca gtggccatgc actgcctgcc agctgagtcc gaagccatct
     5461 ccctggccat gtcggagggc cgtcccttca gcctgagcgg caagagcgag gacctcgtga
     5521 ccgagatgga ggcgcatgtg tcttgcgtgg cgtaattcgg ctctcgctag aggaataaaa
     5581 aaacccacca catgcaatca cctacaccaa ccctctccca accccgagtg gcagatcctt
     5641 ccatgggcaa aaatctaaaa aaagcaagtg tatgcttagc gcattaattc gaaaaaatgc
     5701 tcacacaatg cctaaacctt ccagcagtca gctaacatta ttaatacttt caatgtatgg
     5761 agtagtgcag agatatattg tgttgctgtg agtttttcct gtcttaattc atgattgtga
     5821 tttgagtgta tctctaagaa ggaataatcc acagttctat tatgttctta aatgtaaatg
     5881 cgaatgtaaa tcatattgtt ttggttgtcg gaaattgttt tgccttaaca cttgattttg
     5941 aaataaaaaa aaattacaca caaaaaaaaa aaaaaa
//