From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.rattus mRNA for serotonin transporter.
Date: 21 Jul 92 10:08:14 GMT
Distribution: bionet
Checksum: 30886     6

LOCUS       RATSERTRAN   2278 bp ss-RNA             ROD       21-JUL-1992
DEFINITION  R.rattus mRNA for serotonin transporter.
ACCESSION   X63253
KEYWORDS    serotonin transporter.
SOURCE      Rattus rattus RNA.
  ORGANISM  Rattus rattus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2278)
  AUTHORS   Blakely,R.D., Berson,H.E., Fremeau,R.T.Jr., Caron,M.G., Prince,H.K.
            and Bradley,C.C.
  TITLE     Cloning and expression of a functional serotonin transporter from
            rat brain
  JOURNAL   Nature 354, 66-70 (1991)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 2278)
  AUTHORS   Blakely,R.D.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: stage=Adult; *source: tissue=Brain stem; *source:
            clone_library=lambda gt10 random primed rat brainstem *source:
            (Clontech); *source: clone=pBS4E-10 rSERT; *source:
            is_macronuclear=N; *source: is_proviral=N; *source: is_germline=N;
            From EMBL    entry RRSERTRAN;  dated 09-JUN-1992.
FEATURES             Location/Qualifiers
     CDS             48..1871
                     /function="Protein encodes a plasma membraneNa+/serotonin
                     cotransporter expressed in the ratCNS"
                     /product="serotonin transporter"
                     /codon_start=1
                     /translation="MVFYRRVSPPQRTGQSLAKYPMGTLQSPGTSAGDEASHSIPAAT
                     TTLVAEIRQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMA
                     IFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIIAWA
                     LYYLISSLTDRLPWTSCTNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQ
                     SKGLQDLGTISWQLTLCIVLIFTVIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRG
                     ATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNC
                     YQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIA
                     NMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITC
                     VLGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVAVSWFYGITQFCSDVKEMLGF
                     SPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIVLGYCIGMSSVICI
                     PTYIIYRLISTPGTLKERIIKSITPETPTEIPCGDIRMNAV"
BASE COUNT      501 a    654 c    576 g    547 t
ORIGIN
        1 tcagaaagtg ctgtcagagt gtaaggacag agaggactgt caagaaaatg gtgttctaca
       61 gaagggtgtc cccaccacag cggacagggc agagcctagc caaatatcca atgggtactc
      121 tgcagtcccc aggcacaagt gcaggggacg aagcttcaca ctcgatccca gctgccacca
      181 ccaccctggt ggctgagatt cgccaagggg agcgggagac ctggggcaag aagatggatt
      241 tcctcctgtc cgtcattggc tatgccgtgg acctgggcaa catctggcgg tttccttaca
      301 tatgctacca gaatggcgga ggggccttcc tcctccctta taccatcatg gccattttcg
      361 gggggatccc gctcttttac atggagctcg cactgggcca gtaccaccga aacgggtgca
      421 tttccatatg gaggaagatc tgcccgattt tcaaaggcat tggttacgcc atctgcatca
      481 tcgcctttta catcgcctcc tactacaaca ccatcatagc ctgggcgctc tactacctca
      541 tctcctccct cacggaccgg ctgccctgga ccagctgcac gaactcctgg aacactggca
      601 actgcaccaa ctacttcgcc caggacaaca tcacctggac gctgcattcc acgtcccccg
      661 ctgaggagtt ctacttgcgc catgtcctgc agatccacca gtctaaggga ctccaggacc
      721 tgggcaccat cagctggcag ctgactctct gcatcgtgct catcttcacc gtaatctact
      781 ttagcatctg gaaaggcgtc aaaacatctg gcaaggtggt gtgggtgaca gccaccttcc
      841 catacattgt cctctctgtc ctgctggtga ggggggccac ccttcctgga gcctggagag
      901 gggtcgtctt ctacttgaaa cccaactggc agaaactctt ggagacaggg gtgtgggtag
      961 atgccgccgc tcagatcttc ttctctcttg gcccgggctt tggggttctc ctggcttttg
     1021 ctagctacaa caagttcaac aacaactgtt accaagatgc cctggtgacc agtgtggtga
     1081 actgcatgac aagcttcgtc tctggcttcg tcatcttcac ggtgcttggc tacatggcgg
     1141 agatgaggaa tgaagatgtg tcagaggtgg ccaaagacgc aggccccagc ctcctcttca
     1201 tcacgtatgc agaggcaata gccaacatgc cagcatccac gttctttgcc atcatcttct
     1261 tcctcatgtt aatcacgctg ggattggaca gcacgttcgc aggcctggaa ggtgtgatca
     1321 cagctgtgct ggatgagttc cctcacatct gggccaagcg cagggaatgg ttcgtgctca
     1381 tcgtggtcat cacgtgcgtc ttgggatccc tgctcacact gacgtcagga ggggcatacg
     1441 tggtgactct gctggaggag tatgccacgg ggccagcagt gctcaccgtg gccctcatcg
     1501 aggccgtcgc cgtgtcttgg ttctatggaa tcactcagtt ctgcagcgat gtgaaggaga
     1561 tgctgggctt cagcccggga tggttttgga ggatctgctg ggtggccatc agccctctgt
     1621 ttctcctgtt catcatttgc agttttctga tgagcccacc ccagctacgg cttttccaat
     1681 acaactatcc ccactggagt atcgtcttgg gctactgcat agggatgtcg tccgtcatct
     1741 gcatccctac ctatatcatt tatcggctga tcagcactcc ggggacactt aaggagcgca
     1801 ttattaaaag tatcactcct gaaacaccca cagaaatccc gtgtggggac atccgcatga
     1861 atgctgtgta acacaccctg ggagaggaca cctcttccca gccacctctc tcagctctga
     1921 aaagccccac tggactcctc ccctctaagc caagcctgat gaagacacgg tcctaaccac
     1981 tatggtgccc agactcttgt ggattccgac cacttctttc cgtggactct cagacatgct
     2041 accacattcg atggtgacac cactgagctg gcctcttgga cacgtcaggg agtggaagga
     2101 gggatgaacg ccacccagtc atcagctagc ttcaggttta gaattaggtc tgtgagagtc
     2161 tgtatcatgt ttttggtaag atcatactac cccgcatctg ttagcttcta aagccttcaa
     2221 tgttcatgaa tacataaacc acctaagaga aaacagagat gtcttgctag ccatatat
//