From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens urokinase plasminogen activator surface receptor (uPAR)
Date: 3 Jan 93 22:07:00 GMT
Distribution: bionet
Checksum: 02746 4

LOCUS       HUMUPARAA    1363 bp ss-RNA             PRI       21-DEC-1992
DEFINITION  H.sapiens urokinase plasminogen activator surface receptor (uPAR)
            mRNA.
ACCESSION   X51675
KEYWORDS    urokinase plasminogen activator receptor.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Roldan,A.L., Cubellis,M.V., Masucci,M.T., Behrendt,N., Lund,L.R.,
            Dano,K., Appella,E. and Blasi,F.
  TITLE     Cloning and expression of the receptor for human urokinase
            plasminogen activator, a central molecule in cell surface, plasmin
            dependent proteolysis
  JOURNAL   EMBO J. 9, 467-474 (1990)
  STANDARD  full automatic
COMMENT     From EMBL    entry HSUPARAA;  dated 17-DEC-1992.
FEATURES             Location/Qualifiers
     sig_peptide     47..112
                     /gene="UPAR"
     mat_peptide     113..1051
                     /product="urokinase plasminogen activator receptor"
                     /gene="UPAR"
     CDS             47..1054
                     /gene="UPAR"
                     /product="urokinase plasminogen activator receptor"
                     /codon_start=1
                     /translation="MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQD
                     LCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGN
                     SGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRP
                     KDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYS
                     CKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGD
                     AFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLW
                     T"
BASE COUNT      309 a    396 c    366 g    292 t
ORIGIN      
        1 agagaagacg tgcagggacc ccgcgcacag gagctgccct cgcgacatgg gtcacccgcc
       61 gctgctgccg ctgctgctgc tgctccacac ctgcgtccca gcctcttggg gcctgcggtg
      121 catgcagtgt aagaccaacg gggattgccg tgtggaagag tgcgccctgg gacaggacct
      181 ctgcaggacc acgatcgtgc gcttgtggga agaaggagaa gagctggagc tggtggagaa
      241 aagctgtacc cactcagaga agaccaacag gaccctgagc tatcggactg gcttgaagat
      301 caccagcctt accgaggttg tgtgtgggtt agacttgtgc aaccagggca actctggccg
      361 ggctgtcacc tattcccgaa gccgttacct cgaatgcatt tcctgtggct catcagacat
      421 gagctgtgag aggggccggc accagagcct gcagtgccgc agccctgaag aacagtgcct
      481 ggatgtggtg acccactgga tccaggaagg tgaagaaggg cgtccaaagg atgaccgcca
      541 cctccgtggc tgtggctacc ttcccggctg cccgggctcc aatggtttcc acaacaacga
      601 caccttccac ttcctgaaat gctgcaacac caccaaatgc aacgagggcc caatcctgga
      661 gcttgaaaat ctgccgcaga atggccgcca gtgttacagc tgcaagggga acagcaccca
      721 tggatgctcc tctgaagaga ctttcctcat tgactgccga ggccccatga atcaatgtct
      781 ggtagccacc ggcactcacg aaccgaaaaa ccaaagctat atggtaagag gctgtgcaac
      841 cgcctcaatg tgccaacatg cccacctggg tgacgccttc agcatgaacc acattgatgt
      901 ctcctgctgt actaaaagtg gctgtaacca cccagacctg gatgtccagt accgcagtgg
      961 ggctgctcct cagcctggcc ctgcccatct cagcctcacc atcaccctgc taatgactgc
     1021 cagactgtgg ggaggcactc tcctctggac ctaaacctga aatccccctc tctgccctgg
     1081 ctggatccgg gggacccctt tgcccttccc tcggctccca gccctacaga cttgctgtgt
     1141 gacctcaggc cagtgtgccg acctctctgg gcctcagttt tcccagctat gaaaacagct
     1201 atctcacaaa gttgtgtgaa gcagaagaga aaagctggag gaaggccgtg ggcaatggga
     1261 gagctcttgt tattattaat attgttgccg ctgttgtgtt gttgttatta attaatattc
     1321 atattattta ttttatactt acataaagat tttgtaccag tgg
//