From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human PMP70 mRNA for a peroxisomal membrane protein
Date: 28 Dec 92 21:29:45 GMT
Distribution: bionet
Checksum: 08289 7

LOCUS       HUMPMP70     3285 bp ss-RNA             PRI       01-DEC-1992
DEFINITION  Human PMP70 mRNA for a peroxisomal membrane protein
ACCESSION   X58528
KEYWORDS    peroxisomal membrane protein.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3285)
  AUTHORS   Kamijo,K., Kamijo,T., Ueno,I., Osumi,I. and Hashimoto,T.
  TITLE     Nucleotide sequence of human 70-kDa peroxisomal membrane protein: a
            member of ATP-binding cassette transporters
  JOURNAL   Biochim. Biophys. Acta 1129, 323-327 (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=liver; *source: clone_library=cDNA in lambda-gt11;
            *source: clone=C2, C5, A5, A20, NC1;
               multidrug resistannt protein (P-glycoprotein) related
               From EMBL    entry HSPMP70;  dated 23-OCT-1992.
FEATURES             Location/Qualifiers
     5'UTR           1..24
     mRNA            1..3285
                     /gene="PMP70"
                     /note="cDNA"
     3'UTR           2002..3285
     CDS             25..2004
                     /gene="PMP70"
                     /product="70kDa peroxisomal membraneprotein"
                     /codon_start=1
                     /translation="MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPP
                     LQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVW
                     MIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTK
                     YLYEEYLQAFTYYKKGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYI
                     FKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNS
                     EEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVS
                     RPFLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARIT
                     ELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATP
                     NGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERRKLFYV
                     PQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVQKEYLDNVQLGHILEREGGWDSVQD
                     WMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVS
                     HRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS"
BASE COUNT      997 a    574 c    690 g   1024 t
ORIGIN      
        1 cggctcgctg gtaccggcag tgccatggcg gccttcagca agtacttgac ggcgcgaaac
       61 tcctcgctgg ctggtgccgc gttcctgctg ctctgcctgc tccacaagcg gcgccgcgcc
      121 ctcggcctgc acggtaagaa aagtggaaaa ccaccattac agaataatga gaaagaagga
      181 aaaaaagaac gagctgtggt ggacaaagtg tttttctcaa ggctcataca gatcctgaaa
      241 atcatggtcc ctagaacatt ttgtaaagag acaggttact tggtacttat tgctgttatg
      301 ctggtgtctc gaacatattg tgatgtttgg atgattcaaa atgggacact aattgaaagt
      361 ggtatcattg gtcgtagcag gaaagatttc aagagatact tactcaactt catcgctgcc
      421 atgcctctta tctctctggt taataacttc ttgaagtatg ggttaaatga gcttaaactg
      481 tgcttccgag taaggctcac taaatacctc tatgaggagt atcttcaagc cttcacatat
      541 tataaaaagg ggaatctgga caacagaata gctaatccag accagctgct tacacaagat
      601 gtagaaaaat tttgtaacag tgtagtcgat ctgtattcaa atcttagtaa gccattttta
      661 gacatagttt tgtatatctt taagttaacg agtgcaattg gagctcaggg cccagcgagc
      721 atgatggcct acttggttgt ttctgggcta ttcctaactc gacttcgaag acccattggt
      781 aagatgacaa taactgagca aaagtatgaa ggagaatata gatatgttaa ttctcggctc
      841 atcacaaaca gtgaagaaat tgccttttac aatgggaata aaagagaaaa gcagacagtc
      901 cactcagtct tccgaaaact ggtggaacac ctacataatt tcattttgtt tcggttttca
      961 atgggcttca ttgatagtat tattgccaaa taccttgcca ctgttgttgg ttacctagtt
     1021 gtcagtcgcc ctttcttaga tttgtctcat cctcgacatc tcaagagtac acattcggaa
     1081 cttctagagg attactacca aagtggaaga atgcttttgc gaatgtctca agctctgggt
     1141 cgaatagttt tggctgggcg tgaaatgact agattggccg gttttactgc tcggattaca
     1201 gaattaatgc aagtactgaa ggatttaaat catggcaaat atgagcgcac aatggtctca
     1261 caacaggaaa agggtattga aggagtacaa gtcattccct tgatacctgg tgctggagaa
     1321 atcattattg cagataacat tataaagttt gatcatgttc ctttagcaac gccaaatgga
     1381 gatgttttga tccgagacct taattttgaa gttcgatctg gggctaatgt tctaatttgt
     1441 ggtccaaatg gctgcggaaa gagttcactt ttccgtgttc ttggtgaatt atggcctctt
     1501 tttggaggac gtctaactaa acctgaaaga agaaaattat tttatgttcc tcagagacct
     1561 tacatgaccc ttggaacact tcgagatcaa gtgatatatc cagatggacg agaagatcag
     1621 aaaaggaagg gaatttctga cctagtacag aaggaatact tagacaatgt ccagttgggt
     1681 catatccttg aacgtgaagg aggctgggac agtgttcagg attggatgga cgtactcagt
     1741 ggtggagaaa agcaaagaat ggcgatggca agattatttt atcataaacc ccagtttgcc
     1801 attttggatg aatgcacaag tgcagttagt gtcgacgtgg aaggctacat ttatagtcat
     1861 tgtcgaaagg ttggcatcac tctcttcact gtgtctcata ggaaatctct ttggaaacat
     1921 catgagtact acctgcatat ggatggcaga ggcaactatg aattcaaaca gataacagaa
     1981 gatacagttg agtttggctc ttagagaaat ctggagaact atacctgctt cagtgaaata
     2041 attacagaat atacttagaa aggcaaagta cattgtaaaa taaagttgag cttagttttt
     2101 tttaaaaaaa aaaacaaagc caaccaaatt atattagata cagaataatg gagaacaagt
     2161 tgttaaaaca tttaatatta tataggatat tgctaattgt gtatatgttg gtttaattaa
     2221 taatatgtac taagaatgtc cttattcttg tggttaaaaa cctgcctaaa ttaaattggg
     2281 cttcaatcat gtaacctgat tcatcctggg atgtaaacca ttcgaagtca gctaattgga
     2341 cttttatggc tctatctttt ccttcatgaa gaaccctatt taaaactggg tcatcatttg
     2401 tcctgttcta gcaagatagt cttcagtttc atttcctgtg ccctgtggta gttggaaacc
     2461 atatcataat gtattattta aatgtttaac atcattgcat aacacgttta ttatacagtg
     2521 gcagatttct ttagctgcca cagtaatact cattccttgt gtgtgtcttg gagtgcattt
     2581 gactccagga aaagccattt tggttttcct taactaaatg ataaatgtac ccctctcagt
     2641 ctgcagtatt gagttgttta aagtatatgt gcagtcttgc ttacaaggag gggttaccat
     2701 gtatcacacc taatcttccc aatgtttggg aatattaaaa caccaacagt ccttaacatg
     2761 ccaggctcaa ggtcttataa gagttctaga tttttaagag aattagacaa atttgtgtgt
     2821 gttagaagcc cattcattag aagtgtggtg gttatttggt attaaactca aacagtgcca
     2881 agcttgggaa ggcactacaa tgaaataatg cactgagtat gcaatgctat cactgtcttt
     2941 gactgtgatt ttatgtttaa aaagtatgtt ctaaaattat tatatataca tgggtgaatt
     3001 atgtttccga ggcactgttt tatctctgtg aatcttgaat aactttttta tatttgggtt
     3061 atgatgtcaa acgatcctaa gcgaagatga tttcagttca tcaaatcatc attaatgact
     3121 ttatgtatta tttgcacagg gagaattgaa actgagtata atcaataagc tagatacgaa
     3181 atcagtttct caaactgagc ttcagaaagg ggcattttgt actcttgttt ttgcataact
     3241 ggttttgttt ttttgcagaa ttaactataa caatcactgg ctacg
//