From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens chloride channel protein (CLC-1) mRNA, 3' end.
Date: 18 Aug 92 10:02:22 GMT
Distribution: bionet
Checksum: 29431     5

LOCUS       HUMCLC       2497 bp ss-mRNA            PRI       18-AUG-1992
DEFINITION  Homo sapiens chloride channel protein (CLC-1) mRNA, 3' end.
ACCESSION   M97820 M97578
KEYWORDS    chloride channel.
SOURCE      Homo sapiens adult skeletal muscle cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2497)
  AUTHORS   Koch,M.C., Steinmeyer,K., Lorenz,C., Ricker,K., Wolf,F., Otto,M.,
            Zoll,B., Lehmann-Horn,F., Grzeschik,K.H. and Jentsch,T.J.
  TITLE     The skeletal muscle chloride channel in dominant and recessive
            human myotonia
  JOURNAL   Science 257, 797-800 (1992)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     misc_feature    1..2450
                     /note="ORF"
                     /product="chloride channel"
                     /gene="CLC-1"
                     /partial
     mutation        replace(729,"g")
                     /phenotype="generalized myotonia"
                     /gene="CLC-1"
     polyA_site      2497
BASE COUNT      506 a    727 c    671 g    593 t
ORIGIN
        1 cctcatcctc ttcagcgccc tcttctgcca cctcatctct ccccaggctg ttggctctgg
       61 aatccccgaa atgaagacaa tacttcgtgg ggttgtcctg aaggaatacc tcacaatgaa
      121 agcctttgtg gccaaggttg tcgccctgac tgcgggcctg ggcagtggca tccccgtggg
      181 gaaagagggc cccttcgtcc acattgccag catctgtgct gctgtcctca gcaaattcat
      241 gtctgtgttc tgcggggtat atgagcagcc atactactac tctgatatcc tgacggtggg
      301 ctgtgctgtg ggagtcggct gttgttttgg gacaccactt ggaggagtgc tatttagcat
      361 cgaggtcacc tccacctact ttgctgttcg gaactactgg agaggattct ttgcagccac
      421 gttcagcgcc tttgtgtttc gagtgctggc agtgtggaac aaggatgctg tcaccatcac
      481 tgctctgttc agaaccaatt tccgaatgga tttccccttt gacctgaagg aactaccagc
      541 ttttgctgcc atcgggattt gctgtgggct cctgggagct gtatttgtgt atctgcatcg
      601 ccaagtcatg ctcggtgtcc gaaagcacaa ggccctcagc cagtttcttg ctaagcaccg
      661 cctgctgtat cctggaattg ttacctttgt cattgcctca ttcaccttcc caccaggaat
      721 gggtcaattc atggctggag agttgatgcc ccgcgaagcc atcagtactt tgtttgacaa
      781 caatacatgg gtgaaacacg cgggtgatcc tgagagcctg ggccagtcag ctgtgtggat
      841 tcacccccgg gtcaacgttg tcatcatcat ctttctcttc ttcgtcatga agttctggat
      901 gtccatcgtg gccaccacta tgcccatacc ctgcggaggc ttcatgcctg tgtttgtgct
      961 aggagctgca tttggaaggc tggtaggaga aatcatggcc atgctctttc ctgatggtat
     1021 tttgtttgat gacatcatct acaagatcct acctgggggc tatgcagtaa ttggagcagc
     1081 agcgctgact ggtgccgttt cccacacagt ctccacagct gtgatttgct tcgaattaac
     1141 gggtcagatt gctcacatcc tgcccatgat ggtggctgtt atcttggcca acatggtggc
     1201 ccagagcctg cagccctctc tctatgacag catcatccag gtcaagaagc taccctactt
     1261 gcctgacctt ggctggaacc agctcagcaa atataccatc tttgttgagg acatcatggt
     1321 acgtgatgtg aagtttgttt cagcttctta cacatatggg gagttgcgaa ccctgctcca
     1381 gaccaccaca gtcaagactt taccactggt tgactcaaaa gattcaatga tcctgctggg
     1441 ctcggtggag cggtcggaac tgcaggccct cctgcagcgc cacctgtgtc ctgagcgcag
     1501 gctgcgcgca gcccaagaga tggcgcggaa gttgtcggag ctgccttacg acgggaaggc
     1561 gcggctggct ggggaggggc cccccggcgc gcctccaggc cggcccgagt ccttcgcctt
     1621 tgtggatgag gatgaggacg aagatctctc tggcaagagc gagcttcctc cttcccttgc
     1681 tctccacccc tctactactg cccctctgtc cccagaagag cccaatgggc ctctgcctgg
     1741 ccacaaacag cagccggaag caccagagcc tgcaggtcaa agaccctcca tcttccagtc
     1801 cctgcttcac tgcttgctgg gcagagctcg ccccacaaag aagaaaacaa cccaggattc
     1861 cacagattta gtggataaca tgtcacctga agagattgag gcctgggagc aggagcagct
     1921 gagccagcct gtctgttttg attcctgctg tattgaccag tctcccttcc agctggtgga
     1981 gcagacaacc ctgcacaaga ctcataccct gttttcactc cttggcctcc acctcgctta
     2041 cgtgaccagc atggggaagc tcaggggcgt cctggccctg gaggagctac agaaggccat
     2101 tgaggggcac accaagtctg gggtgcagct ccgccctccc cttgccagct tccggaacac
     2161 gacttcaact cgaaagagta ccggggcacc tccatcttct gcagagaact ggaacctgcc
     2221 tgaggacagg cctggggcca ctggaacagg ggatgtgatt gctgcctccc cagagacccc
     2281 tgtgccatct ccttccccag agccccctct ctccctggcc ccaggcaagg tagagggcga
     2341 gttggaggag ctggagctgg tggagagtcc agggctggaa gaggagctgg ccgacatctt
     2401 gcagggcccc agcctgcgat ccacagacga ggaggatgag gatgaactga tcctttgacc
     2461 ccctcccacg acctcctcat aaagaccgtg gagaggc
//