From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mRNA for eukaryotic initiation factor 4F (gamma subunit).
Date: 13 Jan 93 05:47:58 GMT
Distribution: bionet
Checksum: 15683 10

LOCUS       HUMEIF4F     5080 bp ss-mRNA            PRI       13-JAN-1993
DEFINITION  Human mRNA for eukaryotic initiation factor 4F (gamma subunit).
ACCESSION   D12686
KEYWORDS    eukaryotic initiation factor 4F (gamma subunit).
SOURCE      Homo sapiens (library: lambda DR2) brain cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5080)
  AUTHORS   Yan,R., Rychlik,W., Etchison,D. and Rhoads,R.E.
  TITLE     Amino Acid Sequence of the Human Protein Synthesis Initiation
            Factor eIF-4gamma
  JOURNAL   J. Biol. Chem. 267, 23226-23231 (1992)
  STANDARD  full automatic
COMMENT     Submitted (21-JUL-1992) to DDBJ by: Rhoads Robert E. Dept. of
            Biochemistry and Molecular Biology Louisiana State University
            Medical Center 1501 Kings Highway Shreveport LA 71130-3932 USA
            Phone:  318-674-5162 Fax:    318-674-5180 Email:
            brwnng@ccwf.cc.utexas.edu.
FEATURES             Location/Qualifiers
     polyA_site      4697..4702
     polyA_site      5000..5005
     CDS             369..4559
                     /function="unknown"
                     /standard_name="eIF-4F(gamma)"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
                     /product="eukaryotic initiation factor 4F (gamma subunit)"
                     /codon_start=1
                     /translation="MSGARTASTPTPPQTGGSLEPQANGETPQVAVIVRPDDRSQGAI
                     IADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE
                     ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTV
                     EIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVD
                     LSPVSEPEEQAKEVTASVAPPTIPSATPATAPSATSPAQEEEMEEEEDEEEGEVGEAG
                     EGESEKRGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDL
                     LDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQ
                     PGEQKYEYKSDQWKPPNLEEKKRYDREFLLGFQFIFCQMQKPEGLPHISDVVLDKANK
                     TPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELARGAQAGLGPRR
                     SQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLF
                     RRWRSILNKLTPQMFQQLMKQVTQLAIDTEDASKGSLTSFLRRPFQSPTSLWPIQHVP
                     LPHGAESAHYGKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERE
                     RLKEELEEARDIARRCSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLC
                     RLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRR
                     GDQGPRPLTRSIRRLRWKTSRAHQSAAAHARAVTSVGAVLQALPSAVDFPLWMMVADT
                     VPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAQPSDAASEA
                     ARPATSTLIRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERVNGEGTV
                     GTGLIVSRTPATKRTFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALP
                     PVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVEST
                     LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELV
                     TPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLS
                     WKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRV
                     FDWIEANLSEQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKGDIVLQKYLCDEAE
                     GATGALRLQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVA
                     LKSVTAFFKWLREVRGGV"
BASE COUNT     1305 a   1311 c   1489 g    975 t
ORIGIN      
        1 tctagatggg ggtcctgggc cccagggtgt gcagccactg acttggggac tgctggtggg
       61 gtagggatga gggagggagg ggcattgtga tgtacagggc tgctctgtga gatcaagggt
      121 ctcttaaggg tgggagctgg ggcagggact acgagagcag ccagatgggc tgaaagtgga
      181 actcaagggg tttctggcac ctacctacct gcttcccgct ggggggtggg gagttggccc
      241 agagtcttaa gattggggca gggtggagag gtgggctctt cctgcttccc actcatctta
      301 tagctttctt tccccagatc cgaattcgag atccaaacca aggaggaaag gatatcacag
      361 aggagatcat gtctggggcc cgcactgcct ccacacccac ccctccccag acgggaggca
      421 gtctggagcc tcaagctaat ggggagacgc cccaggttgc tgtcattgtc cggccagatg
      481 accggtcaca gggagcaatc attgctgacc ggccagggct gcctggccca gagcatagcc
      541 cttcagaatc ccagccttcg tcgccttctc cgaccccatc accatcccca gtcttggaac
      601 cggggtctga gcctaatctc gcagtcctct ctattcctgg ggacactatg acaactatac
      661 aaatgtctgt agaagaatca acccccatct cccgtgaaac tggggagcca tatcgcctct
      721 ctccagaacc cactcctctc gccgaaccca tactggaagt agaagtgaca cttagcaaac
      781 cggttccaga atctgagttt tcttccagtc ctctccaggc tcccacccct ttggcatctc
      841 acacagtgga aattcatgag cctaatggca tggtcccatc tgaagatctg gaaccagagg
      901 tggagtcaag cccagagctt gctcctcccc cagcttgccc ctccgaatcc cctgtgccca
      961 ttgctccaac tgcccaacct gaggaactgc tcaacggagc cccctcgcca ccagctgtgg
     1021 acttaagccc agtcagtgag ccagaggagc aggccaagga ggtgacagca tcagtggcgc
     1081 cccccaccat cccctctgct actccagcta cggctccttc agctacttcc ccagctcagg
     1141 aggaggaaat ggaagaagaa gaagatgagg aagaaggaga agtaggggaa gcaggggaag
     1201 gtgagagtga gaagagagga gaggaactgc tccccccaga gagtacccct attccagcca
     1261 acttgtctca gaatttggag gcagcagcag ccactcaagt ggcagtatct gtgccaaaga
     1321 ggagacggaa aattaaggag ctaaataaga aggaggctgt tggagacctt ctggatgcct
     1381 tcaaggaggc gaacccggca gtaccagagg tggaaaatca gcctcctgca ggcagcaatc
     1441 caggcccaga gtctgagggc agtggtgtgc ccccacgtcc tgaggaagca gatgagacct
     1501 gggactcaaa ggaagacaaa attcacaatg ctgagaacat ccagcccggg gaacagaagt
     1561 atgaatataa gtcagatcag tggaagcctc caaacctaga ggagaaaaaa cgttacgacc
     1621 gtgagttcct gcttggtttt cagttcatct tttgccagat gcagaagcca gagggattgc
     1681 cacatatcag tgacgtggtg ctggacaagg ccaataaaac accactgcgg ccactggatc
     1741 ccactagact acaaggcata aattgtggcc cagacttcac tccatccttt gccaaccttg
     1801 gccggacaac ccttagcacc cgtgggcccc caaggggtgg gccaggtggg gagctcgccc
     1861 gtggcgcgca ggctggcctg ggaccccggc gctctcagca gggaccccga aaagaaccac
     1921 gcaagatcat tgccacagtg ttaatgaccg aagatataaa actgaacaaa gcagagaaag
     1981 cctggaaacc cagcagcaag cggacagcgg ctgataagga tcgaggggaa gaagatgctg
     2041 atggcagcaa aacccaggac ctattccgca ggtggcgctc catcctgaat aaactgacac
     2101 cccagatgtt ccagcagctg atgaagcaag tgacgcagct ggccatcgac accgaggacg
     2161 cctcaaaggg gtcattgacc tcatttttga gaaggccatt tcagagccca acttctctgt
     2221 ggcctatcca acatgtgccg ctgcctcatg gcgctgaaag tgcccactac ggaaagccaa
     2281 cagtgactgt gaacttccga aagctgttgt tgaatcgatg tcagaaggag tttgagaaag
     2341 acaaagatga tgatgaggtt tttgagaaga agcaaaaaga gatggatgaa gctgctacgg
     2401 cagaggaacg agaacgcctg aaggaggagc tggaagaggc tcgggacata gcccggcgct
     2461 gctctttagg gaatatcaag tttattggag agttgttcaa actgaagatg ttaacagagg
     2521 caataatgca tgactgtgtg gtcaaactgc ttaagaacca tgatgaagag tcccttgagt
     2581 gcctttgtcg tctgctcacc accattggca aagacctgga ctttgaaaaa gccaagcccc
     2641 gaatggatca gtatttcaac cagatggaaa aaatcattaa agaaaagaag acgtcatccc
     2701 gcatccgctt tatgctgcag gacgtgctgg atctgcgagg gagcaattgg gtgccacgcc
     2761 gaggggatca gggtccaaga ccattgacca gatccataag gaggctgaga tggaagacat
     2821 cgagagcaca tcaaagtgca gcagctcatg caagggcagt gacaagcgtc ggggcggtcc
     2881 tccaggccct cccatcagcc gtggacttcc ccttgtggat gatggtggct gacacagttc
     2941 ccatcagcaa aggtagccgc cccattgaca cctcacgact caccaagatc accaagcctg
     3001 gctccatcga ttctaacaac cagctctttg cacctggagg gcgactgagc tggggcaagg
     3061 gcagcagcgg agggtcagga gcccagccct cagacgcagc atcagaagct gctcgcccag
     3121 ctactagtac tttgattcgc ttctcagccc ttcaacaagc ggtacccaca gaaagcacag
     3181 ataatagacg tgtggtgcag aggagtagct tgagccgaga acgaggcgag aaagctggag
     3241 accgaggaga ccgcctagag cgagtgaacg gggaggggac cgtggggacc ggcttgatcg
     3301 tgtcgcggac acctgctacc aagcggacgt tcagcaagga agtggaggag cggagtagag
     3361 aacggccctc ccagcctgag gggctgcgca aggcagctag cctcacggag gatcgggacc
     3421 gtgggcggga tgccgtgaag cgagaagctg ccctaccccc agtgagcccc ctgaaggcgg
     3481 ctctctctga ggaggagtta gagaagaaat ccaaggctat cattgaggaa tatctccatc
     3541 tcaatgacat gaaagaggca gtccagtgcg tgcaggagct ggcctcaccc tccttgctct
     3601 tcatctttgt acggcatggt gtcgagtcta cgctggagcg cagtgccatt gctcgtgagc
     3661 atatggggca gctgctgcac cagctgctct gtgctgggca tctgtctact gctcagtact
     3721 accaagggtt gtatgaaatc ttggaattgg ctgaggacat ggaaattgac atcccccacg
     3781 tgtggctcta cctagcggaa ctggtaacac ccattctgca ggaaggtggg gtgcccatgg
     3841 gggagctgtt cagggagatt acaaagcctc tgagaccgtt gggcaaagct gcttccctgt
     3901 tgctggagat cctgggcctc ctgtgcaaaa gcatgggtcc taaaaaggtg gggacgctgt
     3961 ggcgagaagc cgggcttagc tggaaggaat ttctacctga aggccaggac attggtgcat
     4021 tcgtcgctga acagaaggtg gagtataccc tgggagagga gtcggaagcc cctggccaga
     4081 gggcactccc ctccgaggag ctgaacaggc agctggagaa gctgctgaag gagggcagca
     4141 gtaaccagcg ggtgttcgac tggatagagg ccaacctgag tgagcagata gtatccaaca
     4201 cgttagttcg agccctcatg acggctgtct gctattctgc aattattttt gagactcccc
     4261 tccgagtgga cgttgcagtg ctgaaaggcg acatagtgct gcagaaatac ctgtgtgacg
     4321 aagcagaagg agctacaggc gctctacgcc tccaggccct tgtagtgacc ttagaacagc
     4381 ctcccaacct gctgcggatg ttctttgacg cactgtatga cgaggacgtg gtgaaggagg
     4441 atgccttcta cagttgggag agtagcaagg accccgctga gcagcagggc aagggtgtgg
     4501 cccttaaatc tgtcacagcc ttcttcaagt ggctccgtga agtcagagga ggagtctgac
     4561 cacaactgag ggctggtggg gccggggacc tggagcccca tggacacaca gatggctccg
     4621 gctagccgcc tggactgcag gggggcggca gcagcggcgg tggcagtggg tgcctgtagt
     4681 gtgatgtgtc tgaactaata aagtggctga agaggcagga tggcttgggg ctgcctgggc
     4741 ccccctccag gatgccgcca ggtgtccctc tcctcccctg gggcacagag atatattata
     4801 tataaagtct tgaaaatttt gaaatttggt gtgtcttggg gtggggaggg gcaccaacgc
     4861 ctgcccctgg ggtccttttt tttattttct gaaaatcact ctcggactgc cgtcctcgct
     4921 gctgggcata tgccccagcc cctgtaccac ccctgctgtt gcctgggcag ggggaagggg
     4981 gggcacggtg cctgtaatta ttaaacatga attcaattaa aaaaaaaaaa aaaaaaaaaa
     5041 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//