From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Dog Na/Cl-dependent taurine transporter mRNA, complete cds.
Date: 22 Jul 92 10:01:19 GMT
Distribution: bionet

LOCUS       DOGNACLTAU   6257 bp ss-mRNA            MAM       22-JUL-1992
DEFINITION  Dog Na/Cl-dependent taurine transporter mRNA, complete cds.
ACCESSION   M95495
KEYWORDS    Na/Cl-dependent taurine transporter.
SOURCE      Canis familiaris kidney cDNA to mRNA.
  ORGANISM  Canis familiaris
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Carnivora; Caniformia; Canoidea; Canidae.
REFERENCE   1  (bases 1 to 6257)
  AUTHORS   Uchida,S., Kwon,H., Yamauchi,A., Preston,A.S., Marumo,F. and
            Handler,J.S.
  TITLE     Molecular cloning of the cDNA for an MDCK cell Na and Cl-dependent
            taurine transporter that is regulated by hypertonicity
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             59..2026
                     /product="Na/Cl-dependent taurine transporter"
                     /codon_start=1
                     /translation="MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKW
                     SSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGGGLPVFFLEVIIG
                     QYTSEGGITCWEKICPLFSGIGYASIVIVSLLNIYYVIILAWATYYLFQSFQSELPWA
                     HCNHSWNTPQCMEDTMRKNKSLWITLSTKNFTSPVTEFWERNVLSLSSGIDDPGSLKW
                     DLALCLLLVWLVCFFCIWKGVKSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKF
                     YLYPDISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNS
                     GTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFF
                     IMLLLLGLDSQFVEVEGQVTSLVDLYPSFLRKGFRREIFIAFMCSISYLLGLSMVTEG
                     GMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGSDNLYDGIEDMIGYRPGPWMKYSW
                     AVVTPVLCVGCFIFSLVKYVPLTYNKVYVYPTWAIGLGWSLALSSMMCVPLVMVIRLC
                     QTEGPFLVRLKYLLTPREPNRWAVEREGYALQLPPGRERGSHETDPHHSRDHDVSSWA
                     DGPLPCCLLTLDSHRTRFTELSICTRIVFFF"
BASE COUNT     1387 a   1619 c   1643 g   1608 t
ORIGIN
        1 cccaggtcca gaacaacaac cttttgctga ggagcctcca aaacaaagtg aggaggacat
       61 ggccaccaag gagaagttgc agtgtctgaa agactttcat aaagacatcc tgaagccatc
      121 cccagggaag agcccaggca cccggcctga agatgaggcc gaggggaagc cccctcagag
      181 ggagaagtgg tccagcaaga tcgactttgt gctctctgtg gctggtggct ttgtcggctt
      241 gggcaacgtc tggcggttcc cgtacctctg ctacaaaaat ggtggaggtg catttctcat
      301 accatatttt attttcctgt ttggcggcgg cctgcctgtg tttttcctag aggtaatcat
      361 aggccagtac acctctgaag gaggcatcac ctgctgggaa aagatctgcc ccttgttctc
      421 cggcatcggc tatgcctcca tcgtgatcgt gtccctcctg aatatatact atgtcatcat
      481 cctggcctgg gccacctact acctgttcca gtccttccaa tcggagctgc cctgggcaca
      541 ctgcaaccac agctggaata cgcctcagtg tatggaagac acgatgcgca agaacaaaag
      601 cctgtggatc accctcagca ccaagaactt cacttctcct gtcaccgagt tctgggagcg
      661 caacgtgctg agcttgtctt ctggaattga cgaccctggc tccttgaagt gggaccttgc
      721 tctctgcctt ctccttgtct ggctggtctg cttcttctgc atctggaagg gtgtcaagtc
      781 cacggggaag gttgtctact tcacggccac tttcccgttc gctatgctcc tggtgctgct
      841 ggtccgtgga ctgacactgc ccggtgctgg cgcaggcatc aagttttatc tgtaccccga
      901 catcagccgc ctcgaggacc cgcaggtctg gattgatgct gggacccaaa tattcttctc
      961 ctatgccatc tgcctggggg ccatgacctc tctggggagc tacaacaaat acaagtacaa
     1021 ctcgtacagg gactgtatgc tgctgggatg cctgaacagt ggtaccagtt ttgtgtctgg
     1081 cttcgcaatt ttttccatcc tgggcttcat ggcacaagag caaggggtgg acattgctga
     1141 tgtggctgag tcagggcctg gcctggcctt cattgcctac ccaaaagctg tgaccatgat
     1201 gccgctgccc acgttttggt ccattctctt ttttattatg cttctcttgc ttggactgga
     1261 tagccagttt gttgaagtcg aaggacaggt cacgtccttg gtcgatcttt acccatcctt
     1321 cctaaggaag ggtttccgtc gggaaatctt catcgccttc atgtgtagca tcagctactt
     1381 gctgggtctg tcgatggtga cggagggtgg catgtatgtg tttcaactct ttgactacta
     1441 tgcagctagc ggtgtatgcc ttttgtgggt tgcattcttt gaatgttttg ttattgcctg
     1501 gatatatggc agcgataacc tttatgacgg tattgaggac atgattggct atcggcctgg
     1561 gccctggatg aagtacagct gggccgtggt cactccagtt ctctgtgttg gatgttttat
     1621 cttctctctc gtcaagtacg tacccctgac ctacaacaaa gtctacgtgt accccacctg
     1681 ggccatcggg ctgggctgga gtctggcctt gtcctccatg atgtgtgtcc ccttggtcat
     1741 ggtcatccgc ctctgccaga cggaagggcc gttcctcgtg agactcaagt acctgctgac
     1801 cccgagggaa cccaaccgct gggccgtgga gcgcgagggc tacgccctac agctcccgcc
     1861 tggccgtgaa cggggctctc atgaaaccga cccacatcat agtagagacc atgatgtgag
     1921 ctcttgggca gacgggccgc ttccctgctg tttactaaca ttagattctc ataggaccag
     1981 gtttacagag ctttctattt gcactaggat tgtttttttt ttttaattgt cacagaaaat
     2041 gttactctgt gtgtgtgtgt gttggtgtgt gtgtgtgtgt gtgtgtgtgg tattgtgcgt
     2101 atgtgtattt tgttttgatt tggggatatt ttgtacaaaa agaaaaccca ccggcagatg
     2161 tccgggacga ggcagagctt tcatattgaa ttagatgtat tttatgggaa cttggtaaat
     2221 ttttctttgt atttttttta catataatta tatatacatt tagagattgt catacagttt
     2281 taccacttga atcgatcttc ttgccagcaa tagatctcgt ttttaaaagc aattcttcgg
     2341 tgcttgtgta gctggcagaa agttctgccc cccaaaaaca cagggtggaa ccgacctgga
     2401 cagtagaccc attttaaggg tgtagtacct tctcagcctg gttcgagtag aagcatatag
     2461 tggggctggg ggagtggggg gaggccccac tagctggcca gacccagaga ggctggagaa
     2521 aggagggcca caagcttcaa tgacacttgt cttagccaat aagagaaatg ccaaaataat
     2581 ggatcaacct ctgagatcaa gggattgact taaggcagac agaggaggcc gtacagcgca
     2641 agtccgattc tctagaaacc gttgtaccag cagcaaaacc ccacctggta cattgagatc
     2701 gagggtggat agtcagaagg actgtcaggc aggttgtcag caccagaggg agcggcaagg
     2761 gctcccggga ggccggtgag gatggcaccc tgacattcag gaggcggact gcttggctgc
     2821 cgcccatggc cagcgcacga ggagccaggg atctcagggc cccaaacctc gcacagatgg
     2881 ggctgttgtg ttttatggga ttctattgtg tcaggttctg gccgtttccc cgctgacatg
     2941 tcttgcagct ccgtgtagga gagaagcatg atgtatctgg tgagggacga ggggtgagcc
     3001 agtggacctt tgggtgtggg cccaggcgtt cagagaggcc tggtgtcagg gaggggtgct
     3061 tttctttcct catctctcca tcctcagctc tgtcctcatc tcccagaggc tgggaaactc
     3121 ctgacaagct ccccgcccag ggctgcccca gctcctagct ggagtgccaa gagtgtttct
     3181 ggaggctccc tgaatcttgg agtcgggcta agcgctccca agccctcctc cccattcggg
     3241 cacaagagca gcccttggtg gtggcttggg agatagtgaa gctcttcagg acttcacaac
     3301 tcctgcagta gccggtgttg gatgcacacc acgtggggac cgaggagagg aggcgaggga
     3361 gcattttcta gaaaggtagg attgttcagg gggctggcac cccagaactg gcttggccaa
     3421 gagcctgatt tagagcggca ttcctctctg aagaagtaga gaaggtactc cacctttaaa
     3481 atcctgagac ggacacgtct ccacccaagc ccccatttgg acctaaactg tgccatttaa
     3541 actgtcactt ccaagttcag agtctcaact caaccaaaac attgtcatgc acaaacgcca
     3601 gtgactgcct cgtggggtgc ggagggtgaa gcccagctca ggtgttgaga gcgggggctc
     3661 tctgaatcct ggaaccctct ccccaaattt gggaggggag gagcctctgg tgtgtgcccc
     3721 ctccccagag gcggaggcaa ccctgaacct cttctctctg gcaagcattc acatttcaca
     3781 tttcactgtt tccaaaggat acactctgcc aaacaatacc cagtcctatt ccaaaccgtt
     3841 aacaattctg tgttcctgtt tttctatgta tttatggttg ccgctgtgtc tgagttgatt
     3901 ttgttgttgt gtcttttcct aattttactg agtagcaatg tgatctgttt tccttcgtct
     3961 catggaactt agtaaactaa ccactgtcca cgattgggga caggtgatgt gtggggtcaa
     4021 ggggtgcttg gtaagctgtg gctgcctggg catttgtggt catctcaggc tataatatct
     4081 cccctccggt aaaaaggcta cagtatttgg ggttggtagg taaactgcaa cattctggaa
     4141 atggcctgag aaaggcttct tctcataaga ttcgcagacc aaattctaga ccaaagacac
     4201 aagcagacca agtccccagg ccctgctgaa ggaaggtcag ccactttccc cgagcccctc
     4261 tcttgacaat ctcccagttt acctgtctcc aatcgggccc tcttgtctac tcccctggcc
     4321 cttgtgtgtc tgcagaactt ggctctgtga gtacaaggtg taatgatgcg tgactttgat
     4381 atgtctccac ataaaggaaa cttgtcattg gagctcatga ctctggtcct cctgtctctg
     4441 gagaacaggc agtcccccca ctctctgcct tgggaatggg tcagaaattc tggtgtccgc
     4501 acctagccca gttggccagc tctgggaggg atgtaaggga gatggttaaa gacctttctg
     4561 aggatgcaga aatgagtaag ggccttaggc taaatctcac ccagggagat gcttctctga
     4621 gcctgccatg ggctgtgtcg gcccctccag ggacagtcct gcacagtcag tcgctccccg
     4681 gtccgcgccc ttggaaaatg gggggcttct gcgaggcccg gagcgcagaa cagaccgggc
     4741 acagcgggca gggactggaa ccaggctgtc ccgagtcagt tccagttgca ggttctctga
     4801 ggggtgtgtg gcaagtggca agtgcgtctc cccagtgttc tccctgaaga cccgagacga
     4861 gcctttatga acaaggaagc gctctgtgcc ccagcattca gggacgagga gaagcacccc
     4921 tcaccccctc cccatcctca aaggtgtggc tctgtaggac aggcgactgc ctctgcccag
     4981 ccagagaggc agcacccctt caccctggcc ctgcacccag tagccctctg agctaggaac
     5041 tgagatccct gttgcatatg aggaaactga ggcccagtga agccagctgt ggaaagaagc
     5101 agaagtcctt gggcaggatt tagcctgagg ctgtgcggga cattcccagg cagctagaag
     5161 cagccttggg tgatttctgg gtggcacaca gccccctctc tgtatctctc gttctcaccc
     5221 cagatcccca gtgcacccct aaaggaggtg gtgaagcacg aggggagcga gctgctctct
     5281 gcctagcaca cggtgatctt gcatccccca caggccgcca cggcacggcg gtccatggtc
     5341 cagccggctt ctccccaaca ctgcccttct ggaaggggaa aagctctggg cagccagtgc
     5401 tcaaggcaga ggtgccagcc ttcccctcga gcctagacac aggccaggac ggatgcaaga
     5461 gaaagctcga ggcggctaga ggtcccgtcc agccccgaga cccggtgcca ggcagcccca
     5521 cgtaaatcgc accgtgcaaa aatccaacaa gcaccaacca aacaaaatcc cgagagcaaa
     5581 actcagagag gggcgtgagt aacccggaag ccagagaaca gcatttccct cgccccccgc
     5641 cctgttaacg cctggccctc agaatgctct tgtttttaat aggaagctgt ttcattgttc
     5701 tcttgtgggt gtcactacag acgtgttctg acagttccct gagggatgga gcatcttgtt
     5761 atatatttgg cttcaaattg agatgttggc tccgtttctc cccccctccc cccaattaat
     5821 tttcgaatcc ctagcaactg tgactgtatt tagcacaaga gaaagctgag atcgtgggtc
     5881 ttgcctcctt ccagaaatat gtctggctca tcaggacttt ttttaagact tcaaaatatt
     5941 tttaagatat tttaaacttt tgtaaaaaaa aaaaacaaca accaacgaga ctcttctgag
     6001 gaggaacatt tgtatctgaa taagatcctc ggtgtataat tcagtcttgc agtatacaag
     6061 cttttgtgta taaatgtttt atgatataat ccctgtattt cgcagggctc ttcttttcct
     6121 cttttgcttt ttagataaat atgtatatcg atattttaaa ttcatctttg ctttttttta
     6181 gaggagtttg taatcacctt ataacatgaa aataaacatt tcctttttaa aatccaaaaa
     6241 acccacgcgt ccgcgac
//