From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Drosophila melanogaster NAD-dependent methylenetetrahydrofolate
Date: 31 Dec 92 01:34:16 GMT
Distribution: bionet
Checksum: 36345 4

LOCUS       DRONMDMC     1343 bp ss-mRNA            INV       17-DEC-1992
DEFINITION  Drosophila melanogaster NAD-dependent methylenetetrahydrofolate
            dehydrogenase-methenyltetrahydrofolate cyclohydrolase (DNMDMC)
            mRNA, complete cds.
ACCESSION   L07958
KEYWORDS    NAD-dependent methylenetetrahydrofolate dehydrogenase.
SOURCE      Drosophila melanogaster (library: cDNA of L. Kauvar) 3-12 hour
            embryo cDNA to mRNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Price,B.D. and Laughon,A.S.
  TITLE     The isolation and characterization of a Drosophila gene encoding a
            putative NAD-dependent methylenetetrahydrofolate
            dehydrogenase-methenyltetrahydrofolate cyclohydrolase
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             121..1194
                     /function="dehydrogenase-cyclohydrolase"
                     /EC_number="1.5.1.5"
                     /gene="DNMDMC"
                     /citation=[1]
                     /note="putative"
                     /product="NAD-dependent methylenetetrahydrofolate
                     dehydrogenase-methenyltetrahydrofolate cyclohydrolase"
                     /codon_start=1
                     /translation="MATVMGPTPPGTGVMWPAIWRTSSKAIGIRQSVQFEFSTRKISQ
                     KPQKEVTISNMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPKPHLTAVIVGEDPASEK
                     YVANKMVACREVGISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINE
                     RTICNAVDVDKDVDGFNEVNIGRTALDMEANIPATPLGVKRLLEHMKIETLGRNAVVV
                     GRSKNVSLPMAILLHADGKYATKAMDATVTICHRYTPPKELARHCRQADIIVVAVGKP
                     GLITKDMVKPGACVIDVGINRIKDESTGQFKLVGDVDFEEVRQVAGHITPVPGGVGPM
                     TVAMLMHNTLKAARKQFDDRKSS"
BASE COUNT      350 a    349 c    367 g    277 t
ORIGIN      
        1 aaatactatt tctcggccag cgaacgacga actactttgt gatagttact ggtgaatctt
       61 caggaggact tgcgatcatc gaactgcttc ctggctgcct tcagcgtgtt gtgcatcagc
      121 atggccaccg tcatgggacc aactccgccg ggcacaggag tgatgtggcc ggcgatctgg
      181 cgaacttctt caaaggccat cggtatccga caatcagtgc agttcgaatt ttccaccagg
      241 aaaatttcgc aaaagccaca aaaagaagtc acaataagca acatggctca aattatcgat
      301 ggcaaggcca tagcccagga ggtgcgcacc caactagcac acgagctcaa gggaatggag
      361 gctgctggct atccgaagcc ccatctcacg gccgtcattg tgggcgagga tccggctagc
      421 gagaagtatg tggctaacaa gatggtcgcc tgccgggagg tgggcatctc cagtgagacc
      481 aagagattgc ccgcctctac cacgcaggag gagctgctgc aactgattgc cgatctgaac
      541 aaggatcccc aggtcacggg gatactggtg cagctgccgg tacccgagca catcaatgag
      601 cgcaccatct gcaatgccgt cgatgtggac aaggatgtgg atggcttcaa tgaggtcaac
      661 atcggacgca cggctctgga catggaggcc aatattccgg ccacgccgct gggagtcaag
      721 cgactgttgg agcatatgaa aatcgaaact ctcggtcgta acgccgttgt ggtgggacgc
      781 tccaagaatg tcagtctacc gatggcaatc ttgctgcacg cggatggcaa gtatgccacc
      841 aaggcaatgg atgccacggt gaccatctgc cacaggtata caccgcccaa ggaactggct
      901 cgccattgcc gccaagcgga tatcattgtg gtcgcagtgg gaaagccggg tttgatcacc
      961 aaggacatgg ttaagcccgg agcctgtgtc atcgacgtgg gcatcaaccg catcaaggat
     1021 gagagcactg gccagtttaa gctggtcgga gacgtggact ttgaagaagt tcgccaggtc
     1081 gccggccaca tcactcctgt gcccggcgga gttggtccca tgacggtggc catgctgatg
     1141 cacaacacgc tgaaggcagc caggaagcag ttcgatgatc gcaagtcctc ctgaagattc
     1201 accagtaact atcgtgcttc gctggccgag aaatagtatt tttatttaat cccctaaacc
     1261 tatattagat agtaaagtta ctgaccacaa gctaacatgc gataaaccca catattttgc
     1321 tatataaaca gaaataatga aat
//