From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rabbit amyloid precursor protein (APP) gene, exon 16.
Date: 21 Jan 93 05:49:55 GMT
Distribution: bionet
Checksum: 04670 4

LOCUS       RABAMPREA    1503 bp ds-DNA             MAM       20-JAN-1993
DEFINITION  Rabbit amyloid precursor protein (APP) gene, exon 16.
ACCESSION   M83558
KEYWORDS    amyloid precursor protein.
SOURCE      Oryctolagus cuniculus Adult Liver DNA.
  ORGANISM  Oryctolagus cuniculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Lagomorpha; Leporidae.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Davidson,J.S., West,R.L., Maroun,L.E. and Kotikalapudi,P.
  TITLE     Sequence and methylation in the beta/A4 region of the rabbit
            amyloid precursor protein gene
  JOURNAL   Biochem. Biophys. Res. Commun. 188, 905-911 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    1084..1184
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="APP"
     misc_feature    395..419
                     /note="25 bp gap"
     misc_feature    942..966
                     /note="25 bp gap"
     exon            1084..1184
                     /number=16
                     /function="membrane bound protein"
                     /standard_name="A4 (beta) region of the APP gene"
                     /product="amyloid precursor protein"
                     /gene="APP"
                     /citation=[1]
                     /note="putative"
     CDS             complement(<1..309)
                     /citation=[1]
                     /note="putative;  ORF1"
                     /codon_start=1
                     /translation="LQIILPLGWSSYIKPTGFSLVSLRVSLEQATPSRPHDCLGQVPD
                     GRQQVPVDSPLTWTDKFLALSFPMETDFLLFLLSLFPTSVYEAAVKLLTHLLTWKSQS
                     R"
BASE COUNT      465 a    267 c    293 g    428 t     50 others
ORIGIN      
        1 tctagattgg cttttccatg tcagcaggtg tgtgagaagt ttcacagcag cctcatagac
       61 agaggtggga aagagtgata agaggaagag caagaaatca gtctccatag gaaaggagag
      121 agccaggaat ttgtcagtcc atgtcagagg ggaatccaca ggaacctgct gcctcccatc
      181 tggcacctgt ccaaggcagt catgtggtct ggagggtgtg gcttgctcaa ggctgacccg
      241 gagtgacact agagagaaac cagttggctt aatgtaagag gaccatccta gaggcagaat
      301 tatctgtaac tagaagcaaa ctgatactca tctgttcaaa caggagcaga cagcctacct
      361 cttgggggaa cctgtggaga atatatgata aagcnnnnnn nnnnnnnnnn nnnnnnnnng
      421 tttttaagct cagattattg tttgaataat gaaattgatt ctagcaatta gtgtaagagt
      481 ctatagcaat tttacagaag gaagaattag taggttatat tttctgttac tctcaaagaa
      541 gcattttaaa atgtactgaa ccaattaaat tctgtatcta taactagaat acttaactaa
      601 ataaattata aatttttttc aatgctttac tgcatagata catgaacata atttgtaatt
      661 ggagcagagc cccaaagtag cggttttgtt ccaccaggta attaatgctc atttctaaag
      721 cctttcatta ttttttttcc tgaagtaatg agatcagatg gaaaggccac ataataggct
      781 aacaatgagc cctaaaccaa gcaaatgtat ctaggagcaa aaccttgcca acctcccaac
      841 cagcatttaa caaccatttt tctcctttat aaaaggagaa aaggcagtgg aagcctcaag
      901 ttcagatttt tttaacttct tttctttgaa ataggtggtg gnnnnnnnnn nnnnnnnnnn
      961 nnnnnntttt tactctttct tgaatagtgt gtagcttaat cagtgtcatt tctaagcaat
     1021 catcatcatt ctctaacttc aggcttgaat aagtttgata gccttgttca tggtattgtt
     1081 catggtaaac taattgatca tcctgcatat tttaattatg atatcatgca ggttccggat
     1141 tgacaaatat caagacagaa gagatctccg aagtgaaaat ggatgcggag ttccgacatg
     1201 attctggata tgaggttcat catcaaaaat tggttagtaa aacaatctcc ctctccccac
     1261 gaccctgtgt gccctgtcaa gtgacctctg gattcttgct cctcgtgtgc cagcaatcaa
     1321 attagggaaa agaaaaaaga aaaataagat gcttccctct aataatatag aactcagaag
     1381 aaaagtaaca atctgtatca agttcttccc gaatagaagg tagttaagcc catgtagaac
     1441 ttaagtggaa ttaatttcag tgcagtaacc actgtcatta acttgcactc tattttctag
     1501 tgc
//