From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human CD40-ligand mRNA, complete cds.
Date: 29 Dec 92 00:45:20 GMT
Distribution: bionet
Checksum: 06924 4

LOCUS       HUMCD40L     1816 bp ss-mRNA            PRI       03-DEC-1992
DEFINITION  Human CD40-ligand mRNA, complete cds.
ACCESSION   L07414
KEYWORDS    CD4/CD8-associated protein; CD40-ligand.
SOURCE      Homo sapiens (library: lambda gt10) cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1816)
  AUTHORS   Gauchat,J.-., Aubry,J.-., Mazzei,G., Life,P., Jomotte,T., Elson,G.
            and Bonnefoy,J.-.
  TITLE     Human CD40-ligand: Molecular cloning, cellular distribution and
            regulation of expression by factors controlling IgE production
  JOURNAL   FEBS Lett. (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     repeat_region   1518..1581
                     /rpt_unit=1518..1519
                     /note="dinucleotide (CA) repeat"
     CDS             40..825
                     /note="hydrophobic region (bps. 76..171); extracellular
                     domain (bps. 172..822); glycosylation sites (bps. 55..63
                     and 757..765)"
                     /product="CD40 surface protein"
                     /codon_start=1
                     /translation="MIETYNQTSPRSAATGLPISMKIFMYLLTVFLITQMIGSALFAV
                     YLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLNCEEIKSQFEGFVKDIMLNK
                     EETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQ
                     LTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPC
                     GQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL"
BASE COUNT      520 a    461 c    343 g    492 t
ORIGIN      
        1 cttctctgcc agaagatacc atttcaactt taacacagca tgatcgaaac atacaaccaa
       61 acttctcccc gatctgcggc cactggactg cccatcagca tgaaaatttt tatgtattta
      121 cttactgttt ttcttatcac ccagatgatt gggtcagcac tttttgctgt gtatcttcat
      181 agaaggttgg acaagataga agatgaaagg aatcttcatg aagattttgt attcatgaaa
      241 acgatacaga gatgcaacac aggagaaaga tccttatcct tactgaactg tgaggagatt
      301 aaaagccagt ttgaaggctt tgtgaaggat ataatgttaa acaaagagga gacgaagaaa
      361 gaaaacagct ttgaaatgca aaaaggtgat cagaatcctc aaattgcggc acatgtcata
      421 agtgaggcca gcagtaaaac aacatctgtg ttacagtggg ctgaaaaagg atactacacc
      481 atgagcaaca acttggtaac cctggaaaat gggaaacagc tgaccgttaa aagacaagga
      541 ctctattata tctatgccca agtcaccttc tgttccaatc gggaagcttc gagtcaagct
      601 ccatttatag ccagcctctg cctaaagtcc cccggtagat tcgagagaat cttactcaga
      661 gctgcaaata cccacagttc cgccaaacct tgcgggcaac aatccattca cttgggagga
      721 gtatttgaat tgcaaccagg tgcttcggtg tttgtcaatg tgactgatcc aagccaagtg
      781 agccatggca ctggcttcac gtcctttggc ttactcaaac tctgaacagt gtcaccttgc
      841 aggctgtggt ggagctgacg ctgggagtct tcataataca gcacagcggt taagcccacc
      901 ccctgttaac tgcctattta taaccctagg atcctcctta tggagaacta tttattatac
      961 actccaaggc atgtagaact gtaataagtg aattacaggt cacatgaaac caaaacgggc
     1021 cctgctccat aagagcttat atatctgaag cagcaacccc actgatgcag acatccagag
     1081 agtcctatga aaagacaagg ccattatgca caggttgaat tctgagtaaa cagcagataa
     1141 cttgccaagt tcagttttgt ttctttgcgt gcagtgtctt tccatggata atgcatttga
     1201 tttatcagtg aagatgcaga agggaaatgg ggagcctcag ctcacattca gttatggttg
     1261 actctgggtt cctatggcct tgttggaggg ggccaggctc tagaacgtct aacacagtgg
     1321 agaaccgaaa cccccccccc cccccccgcc accctctcgg acagttattc attctctttc
     1381 aatctctctc tctccatctc tctctttcag tctctctctc tcaacctctt tcttccaatc
     1441 tctctttctc aatctctctg tttccctttg tcagtctctt ccctccccca gtctctcttc
     1501 tcaatccccc tttctaacac acacacacac acacacacac acacacacac acacacacac
     1561 acacacacac acacacacac agagtcaggc cgttgctagt cagttctctt ctttccaccc
     1621 tgtccctatc tctaccacta tagatgaggg tgaggagtag ggagtgcagc cctgagcctg
     1681 cccactcctc attacgaaat gactgtattt aaaggaaatc tattgtatct acctgcagtc
     1741 tccattgttt ccagagtgaa cttgtaatta tcttgttatt tattttttga ataataaaga
     1801 cctcttaaca ttaaaa
//