From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Xenopus laevis mRNA fragment for IgM VH-region (C40)
Date: 22 Dec 92 22:47:41 GMT
Distribution: bionet
Checksum: 35205 4

LOCUS       XELIMVC40     416 bp ss-mRNA            VRT       23-NOV-1992
DEFINITION  Xenopus laevis mRNA fragment for IgM VH-region (C40)
ACCESSION   X14919 M37531 M37537 X12551
KEYWORDS    complementarity determining region; constant region.
SOURCE      Xenopus laevis RNA.
  ORGANISM  Xenopus laevis
            Eukaryota; Animalia; Chordata; Vertebrata; Amphibia; Lissamphibia;
            Anura; Archeobatrachia; Pipoidea; Pipidae; Xenopodinae.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Schwager,J., Grossberger,D. and Du Pasquier,L.
  TITLE     Organisation and rearrangement of immunoglobulin M genes in the
            amphibian Xenopus
  JOURNAL   EMBO J. 7, 2409-2415 (1988)
  STANDARD  full automatic
COMMENT     *source: tissue=blood; cell type=erythrocyte; library=lambda EMBL3;
            *source: clone=c40;
               From EMBL 27   entry XLIMVC40;  dated 29-JAN-1990.
FEATURES             Location/Qualifiers
     misc_feature    56..142
                     /note="FR1 region"
     misc_feature    143..157
                     /note="CDR1 region"
     misc_feature    158..199
                     /note="FR2 region"
     misc_feature    200..247
                     /note="CDR2 region"
     misc_feature    248..342
                     /note="FR3 region"
     misc_feature    343..370
                     /note="CDR3 region"
     misc_feature    371..403
                     /note="FR4 region"
     CDS             <1..>416
                     /note="(AA-18 to 120) (1 is 3rd base in codon) (416 is 1st
                     base in codon)"
                     /note="pre-IgM VH-region"
                     /codon_start=2
                     /translation="ESVFLFIFMVFAPLCILSQTLQESGPGTVKPSESLRLTCTVSGF
                     ELTSNAVTWIRQPPGKGLEWIGVIASNGGTAFADSLKNRVTITRDTGKKQVYLQMNGM
                     EVKDTAMYYCARHPIYGGFDYWGQGTMVTVTSATSN"
     CDS             <1..52
                     /note="(AA -18 to -1) (1 is 3rd base in codon)"
                     /note="signal peptide"
                     /codon_start=1
                     /translation="GKRFSFHFHGVCPIVYP"
     CDS             56..>416
                     /note="(AA 1 - 120) (416 is 1st base in codon)"
                     /note="IgM VH-region"
                     /codon_start=1
                     /translation="QTLQESGPGTVKPSESLRLTCTVSGFELTSNAVTWIRQPPGKGL
                     EWIGVIASNGGTAFADSLKNRVTITRDTGKKQVYLQMNGMEVKDTAMYYCARHPIYGG
                     FDYWGQGTMVTVTSATSN"
BASE COUNT      111 a     92 c    103 g    110 t
ORIGIN      
        1 ggaaagcgtt tttcttttca ttttcatggt gtttgcccca ttgtgtatcc tctctcagac
       61 attacaagag tctggtcctg gaactgtgaa accctcagag tcactcagac tgacctgcac
      121 agtttctggg tttgagctaa ctagcaatgc tgtgacctgg atcaggcagc ctcctgggaa
      181 gggactggaa tggattggag ttatagcgtc taatgggggc acagcttttg ctgattcact
      241 taaaaacaga gttacaataa ctagagatac tgggaagaag caggtctacc tccaaatgaa
      301 tgggatggaa gttaaagaca ctgccatgta ttactgtgca agacacccca tatacggggg
      361 ctttgactac tggggacaag ggaccatggt caccgtcact tcagctactt caaacc
//