From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus rattus P450p (CYP3A1) gene, 5'end.
Date: 10 Apr 92 10:11:40 GMT
Distribution: bionet
Checksum: 41545     4

LOCUS       RATP450P     1700 bp ds-DNA             ROD       10-APR-1992
DEFINITION  Rattus rattus P450p (CYP3A1) gene, 5'end.
ACCESSION   M86850
KEYWORDS    .
SOURCE      Rattus rattus (library: EMBL1-1-4) DNA.
  ORGANISM  Rattus rattus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1700)
  AUTHORS   Burger,H.-J., Schuetz,J.D., Schuetz,E.G. and Guzelian,P.S.
  TITLE     Paradoxical transcriptional activation of rat liver cytochrome
            P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone
            16-alpha-carbonitrile: Analysis by transient transfection into
            primary monolayer cultures of adult rat hepatocytes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 2145-2149 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     TATA_signal     1495..1499
                     /gene="CYP3A1"
     CDS             1616..1686
                     /product="CYP3A1"
                     /gene="P450p"
                     /codon_start=1
                     /translation="MDLLSALTLETWVLLAVVLVLLYG"
                     /partial
     intron          1687..>1700
                     /note="intron 1"
                     /gene="CYP3A1"
BASE COUNT      382 a    413 c    393 g    509 t      3 others
ORIGIN
        1 gtcgacctag tacaacggat ctgggaaagc ccttgcaagg agtcgtttat aagcatctaa
       61 tttctggcct ttgcctgctc agcttcatct cctggcacca gggcccgcaa aacgtctcgg
      121 tgaatcaggt tcacgggggg ccaagaatga ctgtggaaaa ggaaggaaca ggtaccttcc
      181 tacgagtgtb scctggagtc ttcaggatct tgtgcacttt tctcctctgg tttacaaccg
      241 tcatctttct ctgactttct ttgtttcttc cccgttgctt tagtctttgc agaagacgtg
      301 ctcggttggc tagacatctg gcattccact tcttcccttg gctcctctgc acgccccttc
      361 ttgcttccag acggctccat cttgaattta gatgagacct ccgaaagaaa gttctcctag
      421 cttcccttcc acaggagtct tagagcttcc ctgatgtttg actgtggctc tctgtatctc
      481 agttccccca cctctctctg tgtggaatga atttcacccc cctctwatcc cacccccgta
      541 aacctcagtt cttccctgca aatcttcttc ccacattcac gacttgtttc atgttcctaa
      601 ggacattatc tagtgccatg tgcgtgactg tgagtttgga agcctgcggg tcaccagtgg
      661 gttcacaact gagtacaatt cctccttctc tcattaggca gcaatgagtg tcaggccctg
      721 tctctttctc actggcacca aagggtggca ggtgttgaat tttggtggat agatatagta
      781 gaggaatatt tcttttgagt ctgtgtcttc catatcccag gcttgtctca aacactctat
      841 gttgctttga actttgtctt tgaactttct gatgcccctg cctctggctc tgtaagtgca
      901 ggattgagaa gtctattact tatgatagta cactggggat agagccagag ttctgtgact
      961 gctaagcaga atgtctctcc accaactgat ccttatcatt actcctagcg tttctttttc
     1021 ttttttcaca aagaagcact catcatgagt ctggacagtt gcctcagggg ttgagtgggc
     1081 ttttgcactt ctggagaact ggtgcttgat tcctagacat tacagtggag atataggtcc
     1141 ttgagcagct ccagtatttt tcagtgaagg agaaagtcct tctgtaatgg tgtgcagatg
     1201 acacagtttt ggcttaattt catgaagatt tgaatgaagt cagccttggt gagagattat
     1261 tttatattat cgaatttgct tgaatttctg atagaaacaa actaagaaac tttggtctta
     1321 cttatatggc actgttgttc actgacgcca cccagaatgt taactcaaag gaggtcaaaa
     1381 taggctgtag atgaacttca tgaactgtct aggggaagag agtaccaaag tccacgtgag
     1441 gcagaggtga tccatctact ggctggatcc ctggtgccac ccatctttcc agcatataag
     1501 tactgcaggc tggcctcagt gcagcggttg tgggcagaaa ggaagccctg cagagcatca
     1561 gaggcccagc tagagggaca acacagagga gtaatttgct gacagacctg cagggatgga
     1621 cctgctttca gctctcacac tggaaacctg ggtcctcctg gcagtcgtcc tggtgctcct
     1681 ctacgggtga gtaacttcag
//