From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mucin 2 (MUC2) mRNA, partial cds.
Date: 21 Dec 92 20:19:52 GMT
Distribution: bionet
Checksum: 08756 8

LOCUS       HUMIMUCA     3811 bp ss-mRNA            PRI       18-NOV-1992
DEFINITION  Human mucin 2 (MUC2) mRNA, partial cds.
ACCESSION   M94131
KEYWORDS    mucin.
SOURCE      Homo sapiens intestine cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3811)
  AUTHORS   Gum,J.R.Jr., Hicks,J.W., Toribara,N.W., Rothe,E.M., Lagace,R.E. and
            Kim,V.F.
  TITLE     The human MUC2 intestinal mucin has cysteine- rich subdomains
            located both upstream and downstream of its central repetitive
            region
  JOURNAL   J. Biol. Chem. 267, 21375-21383 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             <1..>3811
                     /gene="MUC2"
                     /product="mucin"
                     /codon_start=2
                     /translation="DCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLY
                     NLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYL
                     EAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQ
                     TLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCT
                     CKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS
                     IITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLV
                     VESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDF
                     GNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEAC
                     VHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWH
                     YEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYV
                     EDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV
                     EKHFNICSITTRPSTLTTFTTITLPTTPTSFTTTTTTTTPTSSTVLSTTPKLCCLWSD
                     WINEDHPSSGSDDGDREPFDGVCGAPEDIECRSVKDPHLSLEQHGQKVQCDVSVGFIC
                     KNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTTTTTLPPTTTPS
                     PPTTTTTTPPPTTTPSPPITTTTTPLPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT
                     TTPSPPTTTTTTPPPTTTPSPPMTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTP
                     SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP
                     PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT
                     TPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT
                     TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFS
                     PFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYP
                     DVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTT
                     TTTENPTP"
BASE COUNT      898 a   1477 c    798 g    638 t
ORIGIN      
        1 ggactgcctg tgcgccgccc tgtcctccta cgcgcgcgcc tgcaccgcca agggcgtcat
       61 gctgtggggc tggcgggagc atgtctgcaa caaggatgtg ggctcctgcc ccaactcgca
      121 ggtcttcctg tacaacctga ccacctgcca gcagacctgc cgctccctct ccgaggccga
      181 cagccactgt ctcgagggct ttgcgcctgt ggacggctgc ggctgccctg accacacctt
      241 cctggacgag aagggccgct gcgtacccct ggccaagtgc tcctgttacc accgcggtct
      301 ctacctggag gcgggggatg tggtcgtcag gcaggaagaa cgatgtgtgt gccgggatgg
      361 gcggctgcac tgtaggcaga tccggctgat cggccagagc tgcacggccc caaagatcca
      421 catggactgc agcaacctga ctgcactggc cacctcgaag ccccgagccc tcagctgcca
      481 gacgctggcc gccggctatt accacacaga gtgtgtcagt ggctgtgtgt gccccgacgg
      541 gctgatggat gacggccggg gtggctgcgt ggtggagaag gaatgccctt gcgtccataa
      601 caacgacctg tattcttccg gcgccaagat caaggtggac tgcaatacct gcacctgcaa
      661 gagaggacgc tgggtgtgca cccaggctgt gtgccatggc acctgctcca tttacgggag
      721 tggccactac atcacctttg atgggaagta ctacgacttt gacggacact gctcctacgt
      781 ggctgttcag gactactgcg gccagaactc ctcactgggc tcattcagca tcatcaccga
      841 gaacgtcccc tgtggcacta cgggcgtcac ctgctccaag gccatcaaga tcttcatggg
      901 gaggacggag ctgaagttgg aagacaagca ccgtgtggtg atccagcgtg atgagggtca
      961 ccacgtggcc tacaccacgc gggaggtggg ccagtacctg gtggtggagt ccagcacggg
     1021 catcatcgtc atctgggaca agaggaccac cgtgttcatc aagctggctc cctcctacaa
     1081 gggcaccgtg tgtggcctgt gtgggaactt tgaccaccgc tccaacaacg acttcaccac
     1141 gcgggaccac atggtggtga gcagcgagct ggacttcggg aacagctgga aggaggcccc
     1201 cacctgccca gatgtgagca ccaaccccga gccctgcagc ctgaacccgc accgccgctc
     1261 ctgggccgag aagcagtgca gcatcctcaa aagcagcgtg ttcagcatct gccacagcaa
     1321 ggtggacccc aagcccttct acgaggcctg tgtgcacgac tcgtgctcct gtgacacggg
     1381 tggggactgt gagtgcttct gctctgccgt ggcctcctac gcccaggagt gtaccaaaga
     1441 gggggcctgc gtgttctgga ggacgccgga cctgtgcccc atattctgcg actactacaa
     1501 ccctccgcat gagtgtgagt ggcactatga gccatgtggg aaccggagct tcgagacctg
     1561 caggaccatc aacggcatcc actccaacat ctccgtgtcc tacctggagg gctgctaccc
     1621 ccggtgcccc aaggacaggc ccatctatga ggaggatctg aagaagtgtg tcactgcaga
     1681 caagtgtggc tgctatgtcg aggacaccca ctacccacct ggagcatcgg ttcccaccga
     1741 ggagacctgc aagtcctgcg tgtgtaccaa ctcctcccaa gtcgtctgca ggccggagga
     1801 aggaaagatt cttaaccaga cccaggatgg cgccttctgc tactgggaga tctgtggccc
     1861 caacgggacg gtggagaagc acttcaacat ctgttccatt acgacacgcc cgtccaccct
     1921 gaccaccttc accaccatca ccctccccac cacccccacc tccttcacca ctaccaccac
     1981 caccaccacc ccgacctcca gcacagtttt atcaacaact ccgaagctgt gctgcctctg
     2041 gtctgactgg atcaatgagg accaccccag cagtggcagc gacgacggtg accgagaacc
     2101 atttgatggg gtctgcgggg cccctgagga catcgagtgc aggtcggtca aggatcccca
     2161 cctcagcttg gagcagcatg gccagaaggt gcagtgtgat gtctctgttg ggttcatttg
     2221 caagaatgaa gaccagtttg gaaatggacc atttggactg tgttacgact acaagatacg
     2281 tgtcaattgt tgctggccca tggataagtg tatcaccact cccagccctc caactaccac
     2341 tcccagccct ccaccaacca cgacgaccac ccttccacca accaccaccc ccagccctcc
     2401 aaccaccacc acaaccaccc ctccaccaac caccaccccc agccctccaa taaccaccac
     2461 gaccacccct ctaccaacca ccactcccag ccctccaata agcaccacaa ccacccctcc
     2521 accaaccacc actcccagcc ctccaaccac cactcccagc cctccaacca ccactcccag
     2581 ccctccaaca accaccacaa ccacccctcc accaaccacc actcccagcc ctccaatgac
     2641 tacgcccatc actccaccag ccagcactac cacccttcca ccaaccacca ctcccagccc
     2701 tccaacaacc accacaacca cccctccacc aaccaccact cccagtcctc caacgactac
     2761 gcccatcact ccaccaacca gcactactac ccttccacca accaccactc ccagccctcc
     2821 accaaccacc acaaccaccc ctccaccaac caccactccc agccctccaa caaccaccac
     2881 tcccagtcct ccaacaatca ccacaaccac ccctccacca accaccactc ccagccctcc
     2941 aacaacgacc acaaccaccc ctccaccaac caccactccc agccctccaa cgactacacc
     3001 catcactcca ccaaccagca ctaccaccct tccaccaacc accactccca gccctccacc
     3061 aaccaccaca accacccctc caccaaccac cactcccagc cctccaacaa ccaccactcc
     3121 cagccctcca ataaccacca caaccacccc tccaccaacc accactccca gctctccaat
     3181 aaccaccact cccagccctc caacaaccac catgaccacc ccttcaccaa ccaccacccc
     3241 cagctctcca ataaccacca caaccacccc ttcctcaact accactccca gccctccacc
     3301 aaccaccatg accacccctt caccaaccac cactcccagc cctccaacaa ccaccatgac
     3361 cacccttcca ccaaccacca cttccagccc tctaacaact actcctctac ctccatcaat
     3421 aactcctcct acattttcac cattctcaac gacaacccct actaccccat gcgtgcctct
     3481 ctgcaattgg actggctggc tggattctgg aaaacccaac tttcacaaac caggtggaga
     3541 cacagaattg attggagacg tctgtggacc aggctgggca gctaacatct cttgcagagc
     3601 caccatgtat cctgatgttc ccattggaca gcttggacaa acagtggtgt gtgatgtctc
     3661 tgtggggctg atatgcaaaa atgaagacca aaagccaggt ggggtcatcc ctatggcctt
     3721 ctgcctcaac tacgagatca acgttcagtg ctgtgagtgt gtcacccaac ccaccaccat
     3781 gacaaccacc accacagaga acccaactcc g
//