From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human alcohol dehydrogenase chi polypeptide (ADH5) gene exons 8-9,
Date: 28 Dec 92 21:43:14 GMT
Distribution: bionet
Checksum: 44026 5

LOCUS       HUMADH507    1519 bp ds-DNA             PRI       02-DEC-1992
DEFINITION  Human alcohol dehydrogenase chi polypeptide (ADH5) gene exons 8-9,
            complete cds.
ACCESSION   M81118
KEYWORDS    alcohol dehydrogenase; chi polypeptide; formaldehyde dehydrogenase.
SEGMENT     7 of 7
SOURCE      Homo sapiens (individual_isolate 620) adult liver DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Hur,M.-W. and Edenberg,H.J.
  TITLE     Cloning and characterization of the ADH5 gene encoding human
            alcohol dehydrogenase 5, formaldehyde dehydrogenase
  JOURNAL   Gene (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            16..154
                     /number=8
                     /gene="ADH5"
     intron          155..285
                     /number=8
                     /gene="ADH5"
     exon            286..1519
                     /number=9
                     /gene="ADH5"
     polyA_site      1466
                     /gene="ADH5"
     intron          order(M81117:182..196,1..15)
                     /number=7
                     /gene="ADH5"
     CDS             join(M81112:359..370,M81113:13..114,M81114:27..168,
                     M81115:19..106,M81116:201..420,M81116:572..832,
                     M81117:46..181,16..154,286..310)
                     /gene="ADH5"
                     /product="alcohol dehydrogenase"
                     /codon_start=1
                     /translation="MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAV
                     CHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKF
                     CLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKI
                     DPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASR
                     IIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMR
                     AALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSE
                     YMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI"
BASE COUNT      438 a    270 c    290 g    521 t
ORIGIN      
        1 tgtgatttct tttaggatgg aagagtgtag aaagtgtccc aaagttggtg tctgaatata
       61 tgtccaaaaa gataaaagtt gatgaatttg tgactcacaa tctgtctttt gatgaaatca
      121 acaaagcctt tgaactgatg cattctggaa agaggtaggc tttctcttta tatatcatag
      181 aatgtaataa tgatgttgag tttgagggga tggagagtcg aaaaacacaa ttttagttgt
      241 cttaaaggta tcatttaaaa cttagtatgt tgcttccttt tacagcattc gaactgttgt
      301 aaagatttaa ttcaaaagag aaaataatgt ccatcctgtc gtgatgtgat aggagcagct
      361 taacaggcag ggagaagcgc ctccaacctc acagcctcgt agagcttcac agctactcca
      421 gaaaataggg ttatgtgtgt cattcatgaa tctctataat caaggacaag gataattcag
      481 tcatgaacct gttttctgga tgctcctcca cataaataat tgctagttta ttaaggaata
      541 ttttaacata ataaaagtaa tttctacatt tgtgtggaaa ttgtcttgtt ttatgctgtc
      601 atcattgtca cggtttgtct gcccattatc ttcattctgc aagggaaagg gaaaggaagc
      661 agggcagtgg tgggtgtctg aaacctcaga aacataacgt tgaactttta agggtctcag
      721 tccccgttga ttaaagaaca gatcctagcc atcagtgaca aagttaatca ggacccaagt
      781 ctgcttctgt gatattatct ttaagggagg tactgtgcct tgttcatacc tgtaccccaa
      841 attcctagga tggcatctgc cttcaggggg cactaaaatg tattattgaa acagcattct
      901 gggcttaaat aggtgtatgt atgtgttggt tgtgactgta ctatttctag tatagtgaac
      961 tacatactga atatccaagt tctcagcacc tacttttgtc aaatcttaac attttgccac
     1021 ttcgagatca cattgccatt cctcccctcc aagaggtaac aattatccac aatttgatgt
     1081 ttatcattcc tgtgttgttg tactttcact gtgtataacc taaaccatct actctttagt
     1141 actgttttat atatttttaa gcctcatact tgctcattct acagcttttt tcactcatta
     1201 ttgtataatt atatctgaag ctctcgttca ttaattttag tcctgtgtag cagaattcaa
     1261 ttacgggaac taccataatt tatctgttct ccagtccagt tgaaggcatg aagttgttgc
     1321 cagtttctgt attataacac tgtagtggaa cattcttctg cattgggctc actgcgtgtt
     1381 acctaagacg tatcacagaa taaacacatt tagccttata gacattgcca aattgctctt
     1441 caaagtaaat gtgagttttt gtgaattaca tgagtatgga atggtgtttt attatgactt
     1501 tagtttgcat tttcctcaa
//