From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for 1D-myo-inositol-trisphosphate 3-kinase B
Date: 11 Sep 92 10:04:40 GMT
Distribution: bionet
Checksum: 23566     8

LOCUS       HUMITKBI     4505 bp ss-RNA             PRI       11-SEP-1992
DEFINITION  H.sapiens mRNA for 1D-myo-inositol-trisphosphate 3-kinase B
            isoenzyme
ACCESSION   X57206
KEYWORDS    inositol 1,4,5-triphosphate 3-kinase; isoenzyme.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4505)
  AUTHORS   Takazawa,K. and Erneux,C.
  JOURNAL   Biochem. J. 278, 883-886 (1991)
  STANDARD  full automatic
COMMENT     *source: stage=2 years old; *source: tissue=hippocampus; *source:
            clone_library=cDNA; *source: clone=hh2T; *source: sex=Female;
            From EMBL    entry HSITKBI;  dated 02-SEP-1992.
FEATURES             Location/Qualifiers
     CDS             102..1520
                     /EC_number="2.7.1.127"
                     /product="1D-myo-inositol-trisphosphate 3-kinase"
                     /codon_start=1
                     /translation="MLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGL
                     AWTRGTGVQSEGTWESQRQDSDALPSPELLPQDQDKPFLRKACSPSNIPAVIITDMGT
                     QEDGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFL
                     HTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKH
                     CESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRT
                     YLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTAT
                     LGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLE
                     VSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDG
                     YLSGLNNLVDILTEMSQDAPLA"
BASE COUNT     1001 a   1213 c   1266 g   1025 t
ORIGIN
        1 gaattccgga gggagggtcc ccaacgctgg gcttgcttgg gggcagcccc tcagcacagc
       61 cggggaccgg gaatgtggag gcgggaattc cttctggcag aatgctggag cctttgccct
      121 gttgggacgc tgcgaaagat ctgaaagaac ctcagtgccc tcctggggac agggtgggtg
      181 tgcagcctgg gaactccagg gtttggcagg gcaccatgga gaaagccggt ttggcttgga
      241 cgcgtggcac aggggtgcaa tcagagggga cttgggaaag ccagcggcag gacagtgatg
      301 ccctcccaag tccggagctg ctaccccaag atcaggacaa gcctttcctg aggaaggcct
      361 gcagccccag caacatacct gctgtcatca ttacagacat gggcacccag gaggatgggg
      421 ccttggagga gacgcaggga agccctcggg gcaacctgcc cctgaggaaa ctgtcctctt
      481 cctcggcctc ctccacgggc ttctcctcat cctacgaaga ctcagaggag gacatctcca
      541 gtgaccctga gcgcaccctg gaccccaact cagctttcct gcataccctg gaccagcaga
      601 aacctagagt gagcaaatca tggaggaaga taaaaaacat ggtgcactgg tctcccttcg
      661 tcatgtcctt caagaagaag tacccctgga tccagctggc aggacacgca gggagtttca
      721 aggcagctgc caatggcagg atcctgaaga agcactgtga gtcagagcag cgctgcctgg
      781 accggctgat ggtggatgtg ctgaggccct tcgtacctgc ctaccatggg gatgtggtga
      841 aggacgggga gcgctacaac cagatggacg acctgctggc cgacttcgac tcgccctgtg
      901 tgatggactg caagatggga atcaggacct acctggagga ggagctcacg aaggcccgga
      961 agaagcccag cctgcggaag gacatgtacc agaagatgat cgaggtggac cccgaggccc
     1021 ccaccgagga ggaaaaagca cagcgggctg tgaccaagcc acggtacatg cagtggcggg
     1081 agaccatcag ctccacggcc accctggggt tcaggatcga gggaatcaag aaagaagacg
     1141 gcaccgtgaa ccgggacttc aagaagacca aaacgaggga gcaggtcacc gaggccttca
     1201 gagagttcac taaaggaaac cataacatcc tgatcgccta tcgggaccgg ctgaaggcca
     1261 ttcgaaccac tctagaagtt tctcccttct tcaagtgcca cgaggtcatt ggcagctccc
     1321 tcctcttcat ccacgacaag aaggaacagg ccaaagtgtg gatgatcgac tttgggaaaa
     1381 ccacgcccct gcctgagggc cagaccctgc agcatgacgt cccctggcag gaggggaacc
     1441 gggaggatgg ctacctctcg gggctcaata acctcgtcga catcctgacc gagatgtccc
     1501 aggatgcccc actcgcctga gctgcccacg ccctccctgg cccccgcctg ggcctccttt
     1561 cctcctcctg tgcttccttt ctcgttccta acttttcctt cacttacacc tgactgaccc
     1621 tcctgaactg cactacaaga cactttgtag aagaggagat gagagtttct agtcattttc
     1681 ctaacttcag ggcttggagg tggtgtttgc actgcttttt gtagagaggg tcacctacta
     1741 gaagagaaat gcccagtctt agaggtgggt caggtgtaga gctggagggg gtccctggct
     1801 gctgagggga ccctaccaga tgagccctgc ctctgggagc cccctaggaa gcaccagcct
     1861 ggacctacca cctgcggagg cctgctgccc cctggcggcc agtgctgtta gagtgctgcc
     1921 aagcacagcc ttatttctgc cggggcctcc ccaccggaga gcccaggggg ccggccgggt
     1981 tcctggtccc tggctgggag cagggctttc tggtagttgg ggcacaaaac catcggggaa
     2041 ccacatgttg actgtgagca aagtgtcttc cgattagcag cctcagggat gccctggtgg
     2101 cctctccagg gctgctcagg caaggccccc cacccatctg gtatggaaac ctgccggctc
     2161 caggccagac ccaggagcca agagaaggct gaagccagct tggctgtgtt ctctgatcta
     2221 ggccttccca gaggaggcga gcagaagctg tgccacttgg aattgcaacc catgagttca
     2281 gaaggcacac tctgccatgc tgagctccaa gggtgctacc aggggaagat gggatctata
     2341 gagtctctgg gccctggccc cagggaggag cacatttttc ttgaccctca cctacctggt
     2401 gctagttggt caaccctgcc tgcatacatg ggctcctgtc atggggccca gagtcccttg
     2461 cagatataga aataggggag gagctcaggt ctgcgccagg caggaagaag gcaggcttct
     2521 ggcttccaga ggtgccgcgg tggcctcctg gcatcatttg ttattgcctc tgaaacaagc
     2581 cttactgcct ggagggctta gattcctgct tccccaatgt agtgtgggta tcttgtaggg
     2641 tatgtggtgg atgccagggc gtgctccagg cacctcttcc tgaagtctct gcatttggag
     2701 attcgtggag aacctattta agcccaattt taactgaaag ccagtgagtc tgatatggaa
     2761 gggaatgtaa aatttgcctg acttcttaag aacaaaaccc ccagctctgt gccccatgct
     2821 ccttggggct tgccacccac tcctttgctg tcagaggtac aggagctggg agagtccagg
     2881 agctagggac acagagggag actatggacc aaggtgtgtg tgtctggagg aaccactgcc
     2941 caccccacca ccccggggtc tctggggaac tgtcaacctg cccacgggac atgtacattt
     3001 ccccttttgt gctggaagtg tgagtgacac ttgctggggg tggagggtgg gacacatgag
     3061 gatgtataag tacagatttt aaaaaaggaa atcaacttac acttcctggc tcttgtttaa
     3121 aacagtggtg agctcctgtg tgggccgact tgctaaaggt cacacacgcg cccggtggag
     3181 cacgagagac ctcgtggcag catgtgatct ggaaggcagg caggacgggg gcgttgggga
     3241 gccaaagtca actctgggcc tctggagcta tagtgacttt tgggctagaa gggaccctgg
     3301 tggtctgtgc ttcagccatt tgcagggcag gggcatcatt aattcagacg taaagattct
     3361 atgaatatgg actggccaaa agttatcctt actccatctg tgaaagaagt ttgctaaagc
     3421 aaatcatgat atgaacaaaa attacagggg acctgtttaa gagaacaaaa tgttccaagc
     3481 actttaggca gacaccagct gtttgcaaac aatgtgctaa tatgcaaatg atgtgcttat
     3541 taaaggaggc ccatggggcc tcttattggc aatacttggc tgtgggttac attaaatatg
     3601 tgaacatagt atgaagtagc atcattttag ggttattctg ttacttaggg tttttgtttt
     3661 ctgttttttt tttctctttt tttgtattta ccgtgctagt tctcttctac acctactctg
     3721 tctctcaagc cattttgcca ctcgcttccc tgccatctgg cccttccctt tgtctcagtg
     3781 ggatagatgg attgtgaaat ggaatctccc agaacccctg ccctggcagc ctggaagacc
     3841 gtgcctgccc agccctcgtc accacaggga ctccttgggt cctggcagtg catgtgccag
     3901 caggcaggac aaactctgtg tacctgtgcc caggtgaatg ggcgcagggt cctcttgccc
     3961 tgtcctgcgg ggggccccac gagttcctgg cattcagcac tgcttagcat tctcggaagg
     4021 tttcttcaac tgcttgcttt tcccaggctt gcctttagtg tcatgtaaga catttttaag
     4081 ttatatttat tttgttgggt tttaaaattg cacagaacac taagaccgaa aggctggact
     4141 cttgtttctc cttgaaagct ttgcctttgt tttgaacttc ctttcccact tggtagaaag
     4201 agcccagaag cagccctggc cctgtaagat ggactctttc atccttcagt tgtatttagc
     4261 tttgagtttc tctgcatctg tccaccccat gtgtatataa cccagcccct ggctctgggg
     4321 tggtcacctc gtcagtgcct tttgttctgg aggagaggac ccccccgcct gccgagaggc
     4381 tctcttcctg ttctgcaccc ctctccccat gggaccttgg agaaaactga actgttacaa
     4441 acccctgcac agtgcctgtc aaacagatgc aaaccttcct gaataaagcc ttggagacgg
     4501 aattc
//