From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mast cell carboxypeptidase A (MC-CPA) gene, exons 1-2.
Date: 24 Jul 92 10:06:59 GMT
Distribution: bionet
Checksum: 48515     5

LOCUS       HUMMCCPA01   2760 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  Human mast cell carboxypeptidase A (MC-CPA) gene, exons 1-2.
ACCESSION   M73716
KEYWORDS    carboxypeptidase; metalloexopeptidase; secretory granules.
SEGMENT     1 of 5
SOURCE      Homo sapiens (library: lambda-gHMCCPA-1) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2760)
  AUTHORS   Reynolds,D.S., Gurley,D.S. and Austen,K.F.
  TITLE     Cloning and characterization of the novel gene for mast cell
            carboxypeptidase A
  JOURNAL   J. Clin. Invest. 89(1), 273-282 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     misc_feature    1759..1764
                     /note="GF-1 site"
                     /gene="MC-CPA"
     TATA_signal     1774..1779
                     /gene="MC-CPA"
     exon            1805..1883
                     /number=1
                     /gene="MC-CPA"
     sig_peptide     1816..1860
                     /gene="MC-CPA"
                     /codon_start=1
     intron          1884..1980
                     /number=1
                     /gene="MC-CPA"
     exon            1981..2056
                     /number=2
                     /gene="CPA3"
BASE COUNT      807 a    584 c    536 g    833 t
ORIGIN
        1 actggaagtc tctgttgaca gcacatgaac attttatcaa ctgtctagag agcatggacg
       61 tgttttttag cacctaccac gaagtcccta acatatcctg tctcactaag cctcacagcc
      121 acttgttaga gtcacattag cattcccatt ttacaaatga ggaaaccaag gcccagaata
      181 actaggcagc ctgctcaagg ggatgtagct agcgtgtggg agccacattg aagtgatgtc
      241 tgtcgaaacc caaagtcaag gtctttcttt ttcactgttc cctggtcaaa agtatcttta
      301 gtcaaaagca atggagcaag catttgcttt gggagttctc agtgctggtg agcttgccca
      361 gtgtcaagaa catgaaggca tttgtaaaac cctcctcttc cttacctgca aggctggagc
      421 cggaaaatcc atttggggaa ataaaaaaaa gtcccgagtt ctaccacaca cccatcagat
      481 agagaagaat ggaattactg ctgctgtata tataacaggg gcgtgtctcc aaccacacta
      541 ttttgatagt acataagcgt gactctgaga agttttatct acagtcagct atacgtttgt
      601 caatgtgaag aggtggtttt caaaaaggaa attctaataa gttaactgat tagataaatt
      661 cacttactct tttaggttac ctatgattct aggtaaaggt gttattctcc cataattaac
      721 caagttgtgt tcaagactaa acatccctcc agagatggtt gtgaatggtc tataggtggc
      781 tttcattaat tcaactctca aaaggcatta tttggcaatt acagcatcca ggctctgaag
      841 acagtgtcca attaataaac attacagcat tgatattttc ttgctgtcag gtagttctca
      901 agttgcctta gaaatagggg tcacctctga ggacagagag aagagaaggg caaagagtta
      961 gggcagtgct ttaggtcttt agtgtttatt tctttaccca gagaagtaca ggaaaaatat
     1021 aacaaaaatg ttatcattgt aaaatctaaa tggtgaacat ttcaatgttc gccatagtac
     1081 ttacagcatt tttagtacat ttatattttg taatttaaat ttttggggtt ttttttgcct
     1141 cccaagtagc tgggattaag gcacctgccg ccacgcccgg ctaatttttg tattttttag
     1201 tagagacagg gtttcaccac gttggccagg ctggtcttga actcctgacc tcagatgatc
     1261 cacccgccgc ggcctcccaa actgctggga ttacaggcgt gagccaccgt gcccagtcaa
     1321 tttaaatgtt tttaatttca caacttacat tctagcttca aaaatatatt ttacattatt
     1381 acgaaccact caccaagatt ttatggccag atacccaaat tcatctcagt ctccaagtgc
     1441 aaattttaaa actaatttct tccatcattc aattcaagca gaatggtaga gtagtatttt
     1501 agaacagata gaactagtaa atcccagctc tgtgaacata ctttctctgt taccttggcc
     1561 aagttatttg ctaaaggcat ttgcttccca tcctgtatct gtaaaatggg tatttcctat
     1621 tgcaaaaggt agataagtag catgtgcttg gtgggttagt gtttttccct ctccagctgg
     1681 aaaaaaaaaa cctggtgtgg gggaagaagg ggaacagttt gtgcaacaga accctaagag
     1741 gaaatcagct gctcatcaag ataagggctg aggcataaaa ctgccagagg gtctcaaggc
     1801 aggcaaagaa gaaccatgag gctcatcctg cctgtgggtt tgattgctac cactcttgca
     1861 attgctcctg tccgctttga caggtaaatc ttacttcctg tgttccagtc tctgtgtaga
     1921 agagaattaa aggttgtttc cttacagttc actttttttt tttcatttgc ctccacaaag
     1981 ggagaaggtg ttccgcgtga agccccagga tgaaaaacaa gcagacatca taaaggactt
     2041 ggccaaaacc aatgaggtaa gcatttagag ggatatttta tcttttctta ctgttctcta
     2101 aaagatgctt cttcttattt tactgtcaat gcccatggga ctacaaaaga ctattgaaca
     2161 taaggggaaa gcaggagcta tctggataat tcagccaatg gccaatactt cacctgttct
     2221 ggttttggtc ttggtttcca agactaccac ttctgttttt cctcccaaaa gcttttcaaa
     2281 caccagcttt ttcaaggtaa aactatgaaa tcaggagctg ttcttggcct ccttatcagg
     2341 gcatctttct cttgcctacg ggtgccattc cctctccatt ctccccactc cgaccctcat
     2401 ctcctctggt gccataattt ctcttgagta ctaactgaaa acgttgaggc actggctaat
     2461 atcaagatgt gaccctttcc aagagcaggt acattttcaa ataagacttt taaagttaga
     2521 tcaatccttt aaaatccaac agcctaatat aattttatca tgtattcagc tgctcctatt
     2581 tatgttgcac cagccacctt atatatgcca tttcaaattc tccagcagat tctcaatgtc
     2641 agggttataa tgtaactcat ttgaaacaga agagctaaag tgcaaagaca ataaattaaa
     2701 tgaccaagat tacacatcaa atttaaaccc acaactgggt ctgggattta ttccagtcaa
//