From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Chicken cysteine-rich fibroblast growth factor receptor (CFR) mRNA,
Date: 26 Jan 93 05:46:48 GMT
Distribution: bionet
Checksum: 32600 9

LOCUS       CHKFGFR      3546 bp ss-mRNA            VRT       25-JAN-1993
DEFINITION  Chicken cysteine-rich fibroblast growth factor receptor (CFR) mRNA,
            complete cds.
ACCESSION   M95766
KEYWORDS    cysteine-rich receptor; fibroblast growth factor receptor.
SOURCE      Gallus gallus (library: Barbara Ranscht's Lambda gt11) 13 day
            embryo brain cDNA to mRNA.
  ORGANISM  Gallus gallus
            Eukaryota; Animalia; Chordata; Vertebrata; Aves; Neornithes;
            Neognathae; Galliformes; Phasianidae.
REFERENCE   1  (sites)
  AUTHORS   Burrus,L.W. and Olwin,B.B.
  TITLE     Isolation of a Receptor for Acidic and Basic Fibroblast Growth
            Factor from Embryonic Chick
  JOURNAL   J. Biol. Chem. 264, 18647-18653 (1989)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Olwin,B.B., Burrus,L.W., Zuber,M.E. and Lueddecke,B.A.
  TITLE     Characterization of a Non-tyrosine Kinase FGF-Binding Protein
  JOURNAL   Ann. N. Y. Acad. Sci. 638, 195-203 (1991)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 3546)
  AUTHORS   Burrus,L.W., Zuber,M.E., Lueddecke,B.A. and Olwin,B.B.
  TITLE     Identification of a cysteine-rich receptor for fibroblast growth
            factors
  JOURNAL   Mol. Cell. Biol. 12, 5600-5609 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..5
                     /gene="CFR"
                     /evidence="EXPERIMENTAL"
                     /citation=[3]
     sig_peptide     6..113
                     /gene="CFR"
                     /evidence="EXPERIMENTAL"
                     /codon_start=1
                     /citation=[3]
     mat_peptide     141..3431
                     /product="cysteine-rich fibroblast growth factor receptor"
                     /gene="CFR"
                     /evidence="EXPERIMENTAL"
                     /codon_start=1
                     /citation=[3]
                     /note="transmembrane domain bases 3330 to 3392"
     3'UTR           3435..3546
                     /gene="CFR"
                     /citation=[3]
     polyA_signal    3531..3536
                     /citation=[3]
                     /note="putative"
     CDS             6..3434
                     /gene="CFR"
                     /evidence="EXPERIMENTAL"
                     /citation=[3]
                     /product="cysteine-rich fibroblast growth factor receptor"
                     /codon_start=1
                     /translation="MAPCGRVRSRCPGPALLLLLALAARPALAGPPAAALQAGPGLNA
                     AGQPAQGAAPGAAGPRGARGGGGGSGGGWKLSEEAVCREDVVRLCSKHSWANNLAVLE
                     CLQDVREPDNEISSDCNHLLWNYKLNLTTDPKFESVAREVCKSTIAEIKECADEPVGK
                     GFLVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKADINLLKCGSIRP
                     GEKDAHSQGEVVACLEKGLVKEAEENDPRVQVSDQCKKAILRVAELSSDDFHLDRHLY
                     FACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCRDALTTRQKLIAQDYKVSYS
                     LAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRM
                     LMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKVVRGEKGNVGLNCQQALQTL
                     IQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVEDCEHR
                     LLELQYFISRDWKLDVVLYRKCQGDASRLCHTHGWNETSELMPPGAVFSCLYRHAYRT
                     EEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCMIDLGKWCSEKTETGQELECLQ
                     DHLDDLVSDCRDIVGNLTELESEDIQIEALLMRACEPIIQTFCHEVADNQIDSGDLME
                     CLIQNKHQKEMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVV
                     ICLSTTVRNDTLQDAKEHRVSLKCRKQLRVEELEMTEDIRLEPELYEACKSDIKNYCQ
                     NVPYGNAQIIECLKEIKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCP
                     EADSKNMLQCLKQNKNSEVMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPKFCQ
                     NILNRAKDDTELEGQVISCLKLKYADQRLSPDCEDQIRVIIQESALDYRLDPQLQMHC
                     SEEISSLCAEEAAAQEQTGQVEECLKVNLLKIKTEMCKKEVLNMLKESKADIFVDPVL
                     HTACALDIKHHCAAIPPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKV
                     APAEGFSDLAMQVMTSPSKNYILSVITVGICVLFLIGLMCGRITKRVTRELKDR"
BASE COUNT      917 a    903 c   1041 g    685 t
ORIGIN      
        1 ccaagatggc gccgtgcgga cgtgtccgga gccgctgccc gggccccgcg ctcctcctgc
       61 tgctggcgct ggcggcgcgg ccggcgctcg ccgggcctcc cgctgccgcc ctgcaggccg
      121 gacccggctt gaacgcggcg gggcagcccg cgcagggagc ggcgcccggt gccgcgggcc
      181 cgcggggagc ccgaggcggc ggaggcggct ccggcggcgg gtggaagctg tcggaggagg
      241 cggtgtgccg cgaggacgtg gtgcggctgt gctccaagca cagctgggcc aacaacctgg
      301 ccgtgctcga gtgcctgcag gacgtccgcg agccagacaa cgaaatctct tcagactgca
      361 accacctcct gtggaactac aagctgaacc tgactacaga tcccaagttt gagtccgtgg
      421 ccagagaagt ctgcaagtcc accatcgcag agatcaagga gtgtgcagat gaaccagttg
      481 gcaaaggctt cttggtgtcg tgtttggtgg atcacagagg caacatcacg gagtaccagt
      541 gccatcagta catcaccaag atgacagcca ttatcttcag cgattaccgg ctgatctgcg
      601 gcttcatgga cgactgcaag gctgacatca acctcctgaa atgcggcagc atccgacccg
      661 gggaaaagga cgcccactcc cagggagagg tggtggcatg cctggaaaaa ggcctggtga
      721 aagaggcaga ggagaacgac cctcgtgttc aggtttctga tcagtgtaag aaggcgatcc
      781 tccgcgtagc agagctctct tcggatgatt tccacttgga ccgccatctc tactttgcct
      841 gccgagacga cagggagaga ttctgtgaga atactcaggc tggggaaggc cgagtttaca
      901 agtgcctctt taatcacaag tttgaagaat caatgagtga gaagtgccgt gacgcgctga
      961 cgacgcgcca gaagctgatt gcccaggact acaaagtcag ctactcactg gccaagtcct
     1021 gtaagagcga cctgaagaag taccgctgca acgtggagaa cctgccccgc tcccgggaag
     1081 ccaggctctc ctacctgctg atgtgcctgg agtctgctgt gcacagaggt cggcaggtga
     1141 gcagcgagtg ccagggagag atgctggact accgacgcat gctcatggaa gacttctccc
     1201 tgagcccaga aatcatcctg agctgccgtg gggagattga gcaccactgc tccgggctgc
     1261 accgcaaggg ccgcacgctg cactgcctga tgaaagtcgt gcgtggagag aagggcaacg
     1321 tggggctgaa ctgccagcag gcgctccaaa cgctgatcca agaaacggac cctggtgcag
     1381 attatcgcat cgaccgagcc ctgaatgagg cctgtgaatc tgtcatacag actgcctgca
     1441 agcacatacg gtccggggat cccatgattc tgtcctgcct gatggagcac ctgtatacgg
     1501 aaaagatggt ggaggactgt gagcatcggc tcctggaact ccagtatttc atatctcggg
     1561 actggaagtt ggatgtggtc ctttaccgaa agtgccaggg cgatgcctcc cgcctctgcc
     1621 atacccatgg ctggaatgag accagcgagc tgatgccccc gggggctgtg ttctcctgct
     1681 tgtacaggca tgcctaccgc acagaggagc agggacggag gctatcacgg gagtgcagag
     1741 cggaggtgca gcggatcctc caccagcgtg ccatggatgt gaagctggac ccggccctgc
     1801 aggacaagtg catgatcgac ctgggcaagt ggtgcagtga gaaaacagag acagggcagg
     1861 aactggaatg tcttcaggac catctcgatg acttggtgtc tgattgcaga gacatagtgg
     1921 gaaacctgac tgagctggag tctgaggaca ttcaaatcga agccttgctg atgagagcat
     1981 gcgagcccat catccagacc ttctgtcatg aggttgcaga taaccagatt gattctgggg
     2041 acctgatgga gtgtttaata cagaacaaac accagaagga aatgaatgaa aaatgtgcaa
     2101 tcggagttac tcacttccag ctggttcaaa tgaaagactt caggttctcc tacaagttca
     2161 aaatggcttg caaggaggat gtgctgaaac tttgccccaa catcaaaaaa aaggtggatg
     2221 tagtgatctg cctgagcaca acggtgcgca atgacactct gcaggacgcc aaggagcaca
     2281 gggtatctct gaagtgccgc aagcagctgc gtgtggagga gctagaaatg accgaggata
     2341 tcagactgga accagagctc tacgaggctt gtaaaagtga catcaagaat tactgccaaa
     2401 acgttcccta tggcaatgct cagatcatag aatgcctgaa agaaatcaag aagcagttga
     2461 gtacccggtg ccaccagaag gtgttcaagc tgcaggagac agagatgatg gatccagagc
     2521 tggactacac actgatgaga gtctgcaagc agatgatcaa gcgtttttgc ccagaagcag
     2581 actcaaaaaa catgttgcag tgtttgaaac aaaacaagaa cagtgaagtg atggatccaa
     2641 agtgcaagca aatgataacc aagcgccaga tcacacagaa cacagattac cgcctaaatc
     2701 cggtgctgag gaaggcctgc aaagcagaca taccaaagtt ctgccagaat attctgaata
     2761 gagccaagga tgatacagag ttggagggac aggtcatctc ctgcctgaag ctgaagtatg
     2821 cagaccagcg tctctctcca gactgcgagg accaaattcg agtgatcatc caggaatcag
     2881 cccttgatta tcgactggat ccccagcttc agatgcattg ctctgaagag atttccagct
     2941 tgtgtgctga agaggcagca gctcaggagc agactgggca ggtggaagaa tgcctgaaag
     3001 tgaacctgct gaaaataaaa accgaaatgt gcaagaagga ggtgctcaac atgctgaagg
     3061 agagcaaggc agatatcttt gtggacccag tgctgcacac agcctgtgcc ctggacatta
     3121 aacaccactg tgctgctatt cctccaggga gaggacgcca aatgtcatgc ttaatggaag
     3181 ctttggagga caagcgtgtg aggctgcagc ctgaatgcaa gaaacgcctt aatgatcgta
     3241 ttgaaatgtg gagctatgct gcaaaggttg ccccagcgga aggcttctct gaccttgcca
     3301 tgcaagttat gacctctccg tccaagaatt acatattgtc tgtgatcacg gttggcatct
     3361 gtgtactctt cctgatcggc ctgatgtgtg gacgcatcac caagcgggtg acaagagagc
     3421 tcaaggacag gtagagcctg gattgcctgc tggagaaatg cctgcccagt gcccagtttt
     3481 gtacagccct cctctgtata gtctacccac cccctcttgt gagagaggag aataaaaaaa
     3541 aaaaaa
//