From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus PEA3 mRNA
Date: 10 Apr 92 10:09:44 GMT
Distribution: bionet
Checksum: 59480     5

LOCUS       MUSPEA3      2410 bp ss-mRNA            ROD       10-APR-1992
DEFINITION  M.musculus PEA3 mRNA
ACCESSION   X63190
KEYWORDS    PEA3 polypeptide; oncogene.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2410)
  AUTHORS   Xin,J.H., Cowie,A., Lachance,P. and Hassell,J.A.
  TITLE     Molecular cloning and characterization of PEA3, a new member of the
            Ets Oncogene family that is differentially expressed in Mouse
            embryonic cells
  JOURNAL   Genes Dev. 6, 481-496 (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=mammary; *source: cell_type=epithelium;
            From EMBL    entry MMPEA3;  dated 26-MAR-1992.
FEATURES             Location/Qualifiers
     CDS             126..1793
                     /gene="PEA3"
                     /translation="MTKSSNHNCLLRPENKPGLWGPGAQAASLRPSPATLVVSSPGHA
                     EHPPAAPAQTPGPQVSASARGPGPVAGGSGRMERRMKGGYLDQRVPYTFCSKSPGNGS
                     LGEALMVPQGKLMDPGSLPPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSEN
                     LAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSRQIAIKSPAPGAPGQS
                     PLQPFSRAEQQQSLLRASSSSQSHPGHGYLGEHSSVFQQPVDMCHSFTSPQGGGREPL
                     PAPYQHQLSEPCPPYPQQNFKQEYHDPLYEQAGQPASSQGGVSGHRYPGAGVVIKQER
                     TDFAYDSDVPGCASMYLHPEGFSGPSPGDGVMGYGYEKSLRPFPDDVCIVPKKFEGDI
                     KQEGIGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVAR
                     LWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSLAFPDNQR
                     PALKAEFDRPVSEEDTVPLSHLDESPAYLPELTGPAPPFGHRGGYSY"
     misc_feature    410..491
                     /note="ETS domain"
     misc_feature    410..511
                     /note="DNA binding domain"
     polyA_signal    2382..2387
BASE COUNT      521 a    744 c    645 g    500 t
ORIGIN
        1 gaattccgtg gatgtgcttt aaaaccacac ctaacgtttg agcacaagtc tcacgaactg
       61 gcgctacaac ttcatcagaa acgaagtctc caaatctgtc caacgcaaaa acacaaagga
      121 gtctaatgac taagtcttcc aaccacaact gtctgctgcg cccggaaaac aagccggggc
      181 tctggggacc cggggctcag gccgcctcgc tccggcctag ccccgccacc ttagttgtgt
      241 catcccccgg gcatgctgag catccccccg cggctccggc acagacgccc ggacctcagg
      301 tctctgcctc cgcgcggggg cccggccctg tggccggagg gagcggccgg atggagcgga
      361 ggatgaaagg cggatacttg gaccagcgag tgccctacac cttctgcagc aaatctcccg
      421 gaaatgggag cttgggcgaa gcgctgatgg tcccgcaggg aaagctcatg gacccgggct
      481 ccctgccgcc ttccgactca gaagatctct tccaggacct cagtcacttc caagagacgt
      541 ggctcgcaga agctcaggta ccggacagtg atgagcagtt tgttcctgat ttccattcag
      601 aaaacttagc tttccatagc cccaccacca ggatcaagaa ggaaccccag agtccccgca
      661 cagaccccgc cctgtcctgc agcaggaagc caccactccc ctaccaccat ggagagcagt
      721 gcctttactc cagacaaatc gccatcaagt cccccgctcc cggtgcccct ggacagtcgc
      781 ccctgcagcc cttttccagg gcagaacagc agcagagcct cctgagagcc tccagctctt
      841 cccagtccca ccctggccac gggtaccttg gtgagcacag ctccgtcttc cagcagcccg
      901 tggacatgtg ccactccttc acatctcctc agggaggggg ccgggaacct ctcccagccc
      961 cctatcaaca ccaactgtcg gagccctgcc caccctaccc ccagcagaac ttcaagcagg
     1021 agtaccatga ccccctgtac gaacaggctg gccagcccgc ttcaagccag ggtggggtca
     1081 gtgggcacag gtacccaggg gcgggggtgg tgatcaaaca ggagcgcaca gacttcgcct
     1141 acgactcaga tgtccctgga tgtgcatcaa tgtacctcca cccagagggc ttctctggac
     1201 cctctccagg tgatggagtg atgggttatg gctatgaaaa atcccttcga ccattcccag
     1261 atgatgtctg cattgtccct aaaaaatttg aaggagacat caagcaggaa gggattggag
     1321 ctttccggga ggggccaccc taccagcgcc ggggtgcctt acaactgtgg cagtttctgg
     1381 tggccctgct ggatgaccca acaaatgctc atttcattgc ttggacaggc cggggaatgg
     1441 agtttaaact aattgaacct gaagaggttg ccaggctctg gggtatccag aagaaccggc
     1501 cagccatgaa ttatgacaag ctgagccgct cgctgcgata ctattatgag aaaggcatca
     1561 tgcagaaggt ggctggcgaa cgctacgtgt acaagtttgt gtgcgagccg gaggccctgt
     1621 tctctctggc cttcccagat aatcaacgtc cagctctgaa ggctgagttt gaccggccag
     1681 tcagtgagga ggacacagtc cctttgtccc acttggatga gagtcctgcc tacctcccag
     1741 aactcactgg ccccgctccg cccttcggcc acagaggtgg atattcttac taggcaccag
     1801 tggcttcccc ttgacatggt ggggttgctc agtgtatata tcaactgatt tggtattggt
     1861 gaaggccctc tttctgatgc ctgtagaagt ctctggggtc agagctccac tatcccatct
     1921 gatactcctg gccagactca gctgctaacc agagtctgcg ggaaagacag tggaggcagg
     1981 ccaaatctaa aggcagtagc tgaagttcgc tgtggctcac ctgtaccttc agttcagctt
     2041 ggcctctgcc taggtcttgc tcagaggcca agttcctcac ccccaccaca gagatccagt
     2101 gttctattct ggggacatac agggacttcc cttgtttatt atggcaacag ggccaagggg
     2161 attctcagaa caccctgtgt ctcccctctc ccaacccccc atgggagaca aagttctgcc
     2221 tggcttctgc cctgaacagg ggggtcctgt gttcttggtg ctgtgctctg ggaggcagga
     2281 gcatgtgggc ggcagctggg ggggggtgtg gaagtagaga tggctctctg ccctaggcct
     2341 acccaggcct aattccacct ttgcctctta tgccagacct taataaagcc tctgcttctc
     2401 cccggaattc
//