From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens defensin 5 gene, complete cds.
Date: 26 Jan 93 05:47:49 GMT
Distribution: bionet
Checksum: 57725 5

LOCUS       HUMDEF5A     2880 bp ds-DNA             PRI       25-JAN-1993
DEFINITION  H.sapiens defensin 5 gene, complete cds.
ACCESSION   M97925
KEYWORDS    defensin 5.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2880)
  AUTHORS   Jones,D.E. and Bevins,C.L.
  TITLE     Paneth cells of the human small intestine express an antimicrobial
            peptide gene
  JOURNAL   J. Biol. Chem. 267, 23216-23225 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            join(1359..1570,2550..2786)
                     /product="defensin 5"
     CAAT_signal     1267..1271
     TATA_signal     1328..1334
     exon            1359..1570
     exon            2550..2786
     polyA_signal    2770..2775
     CDS             join(1399..1570,2550..2662)
                     /product="defensin 5"
                     /codon_start=1
                     /translation="MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAI
                     SFAGNGLSALRTSGSQARATCYCRTGRCATRESLSGVCEISGRLYRLCCR"
BASE COUNT      879 a    595 c    547 g    859 t
ORIGIN      
        1 caaatataga gactctccaa gggcccactg agccccaaag gatttggatc aaatatggtg
       61 atattatgga aatatgtagt aatatcttaa aaatgtgtaa gatatagtct cttttttttt
      121 ttttttaaga gaaggggtct cactatgttt ttaggctggt atcgaactcc tggtctccag
      181 tgatcctccc acctcagcct gtcaaatagc tagaaatata ggcatgtacc accatgctgg
      241 cttaagatgc attctttgac acagcaattc tatttctata agtttatcca tataggtaag
      301 agaacatata tacaagataa tcactgtaac tttacttatt actgcaaaag tttaaaaata
      361 accaaattgt aataatttta taatatttta tcagtacaaa aaataagtga tggcatatac
      421 aaaccctggg atagtataag gctattaaaa ttataatagc attccatgta ttttgatata
      481 caaagtgcca atgttacagg tgaaaaaagc gaagtgcaga atactatgtg taactgttaa
      541 tagtgatggt ttgctgggtc agaactgaag gcctgggggt agaaatgaga gctcatgact
      601 tctacctttt gaatgttgtt ccttgtgcat gatttacaat tttctaaaac taaaaaaaaa
      661 atctcagaaa ggggctgtac gcacctaaat tactttgata ttccccaaag tggagagaag
      721 tacccgctac acattttatg tgatgcattc agatcacacc aactccttga actaaatccg
      781 aatttttatt ttaatctgat aaacttggcc tactatttta ctgaactcat ttcccctata
      841 gcctgataag gtcattgacc tctccatact ggcaccagcg ggagactact cacctcgaga
      901 tctcaaaagc ctcctacatg aggttagtaa tatccctgaa tcctgcaatg aattaactct
      961 ctactccact gggtcccagg tctgccccca gagagtcatc cagagagtac cagggaccat
     1021 cttcagaaaa caagaggcat ttgatcccca aacttcttga atgaaagcgc tgttgttttt
     1081 cttttttgaa tatataaaag taaatactca agcagatggg aaacagaaca ggatagtaat
     1141 acccttatca tcattaacac cttggatcaa gaagaggcat taagcataca gactcacgct
     1201 ttgatgaaag ctgggagaaa gaggagcatc aaagggatct tgagaacaaa ggcagtcctt
     1261 cccctcccaa tcacatgccc acctcctctc actgcagctt ctgtctcagg tcttctccca
     1321 gcagagctat aaatccaggc tgactcctca ctccccacat atccactcct gctctccctc
     1381 ctgcaggtga ccccagccat gaggaccatc gccatccttg ctgccattct cctggtggcc
     1441 ctgcaggccc aggctgagtc actccaggaa agagctgatg aggctacaac ccagaagcag
     1501 tctggggaag acaaccagga ccttgctatc tcctttgcag gaaatggact ctctgctctt
     1561 agaacctcag gtaggagaca tcaatcttgc acatctgcaa aatctagaaa aaaaggattg
     1621 gagaaaggat ctggagtcaa gtgtggaaag gtctacctca cttgagtgac tttacttaat
     1681 cttcctggac cttgattttc tcatctataa attaatcagt gagaaccaaa taaatctaaa
     1741 agattttctt ttttctaaga ctttcagctc caagatattt ctgtgaaatt tgctactttt
     1801 aagatagaaa gagctacact gactagttct ttgtagatct aaatgggcag acttagttat
     1861 atagagagtg ttttactttg tccattggaa aagcttttag aacctagaga ggaacctata
     1921 ggtgtgtttt gatgtaggct aataggcttg attaaatctt tctacaatac atccttagat
     1981 caaaacatca tattgtgtct catacatata cacaattatt gtttgtcaat taaaacaagt
     2041 aaatatgtaa aatgttaaaa aaaaaaaaaa aaaaaaaagg agagacagag aatgaagaat
     2101 ttgaatttgg aaagtcttca aagactcctt gagcaccaaa gtatttggtc catgacatta
     2161 gcatgcacaa tgcggcattt cagaaactga ttcaggtgct ttagggagcc ttgttaggac
     2221 ctggaaatca cacatggagg tcaagattag gcgtgtggat gaagcagaat gaagagtagg
     2281 taaccctgag gttgagaggt atattgttgg accagggagc aggtaataaa tacatcctgg
     2341 atagactcac atggggaaaa aaactatgat cttgcatgac taacacatag ctagtaagat
     2401 ttcttgtcac ttacgacaaa gacatgaatt ttctccatcc taacatgact gatacagtgt
     2461 ctcttattta gactatctca gttagtctgg ctgtgcttgt cctttttccc acctccctcg
     2521 ctgtgcctga ccctctcttc tttccacagg ttctcaggca agagccacct gctattgccg
     2581 aaccggccgt tgtgctaccc gtgagtccct ctccggggtg tgtgaaatca gtggccgcct
     2641 ctacagactc tgctgtcgct gagcttccta gatagaaacc aaagcagtgc aagattcagt
     2701 tcaaggtcct gaaaaaagaa aaacatttta ctctgtgtac cttgtgtctt tctaaatttc
     2761 tctctccaaa ataaagttca agcattaaac ttagtgtgtt tgaccttttt aattttcttt
     2821 tctttttcct tttttttctt ttgctttgtt atatggtggt ttgtatggtt cctttgtatt
//