From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Candida albicans protein kinase (ERK1) gene, complete cds.
Date: 31 Dec 92 01:49:01 GMT
Distribution: bionet
Checksum: 40342 5

LOCUS       YSAERK1      1681 bp ds-DNA             PLN       18-DEC-1992
DEFINITION  Candida albicans protein kinase (ERK1) gene, complete cds.
ACCESSION   M76585
KEYWORDS    protein kinase.
SOURCE      Candida albicans (strain WO1) (library: partial Sau3A) DNA.
  ORGANISM  Candida albicans
            Eukaryota; Fungi; Eumycota; Deuteromycotina.
REFERENCE   1  (bases 1 to 1681)
  AUTHORS   Whiteway,M., Dignard,D. and Thomas,D.Y.
  TITLE     Dominant negative selection of heterologous genes: isolation of
            Candida albicans genes that interfere with Saccharomyces cerevisiae
            mating factor-induced cell cycle arrest
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 9410-9414 (1991)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Whiteway,M.S., Dignard,D. and Thomas,D.Y.
  TITLE     Dominant negative selection of heterologous genes: Isolation of
            Candida albicans genes that interfere with Saccharomyces cerevisiae
            mating factor-induced cell cycle arrest
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 9410-9414 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     variation       202..203
                     /note="addition of 24 bp (caa)8 repeat between bp 202 and
                     203 in clone M152p8"
     misc_feature    326..349
                     /note="protein kinase motif near ATP-binding site (by
                     homology)"
     CDS             104..1357
                     /gene="ERK1"
                     /product="protein kinase"
                     /codon_start=1
                     /translation="MMNIDQHHQLQQQHQQQMLQQQAQAQAQAQAQAQQQQQAAAAAA
                     AANAAATTSSSSPRQVSFNVSDHYQILEIVGEGAYGIVCSAIHKPSQQKVAIKKIEPF
                     ERSMLCLRTLRELKLLKHFNHENIISILAIQRPINYESFNEIYLIQELMETDLHRVIR
                     TQNLSDDHIQYFIYQTLRALKAMHSANVLHRDLKPLNLLLNSNCDLKICDFGLARSIA
                     SQEDNYGFMTEYVATRWYRAPEIMLTFQEYTTAIDVWSVGCILAEMLSGRPLFPGRDY
                     HNQLWLIMEVLGTPNMEDYYNIKSKRAREYIRSLPFCKKIPFSELFANTNNNTSTSNT
                     GGRTNINPLALDLLEKLLIFNPAKRITVEDALKHPYLQLYHDPNDEPISDKIPEDFFD
                     FDKMKDQLTIEDLKKLLYEEIMKPL"
BASE COUNT      630 a    227 c    257 g    567 t
ORIGIN      
        1 ggagaaaagc ctattttttt ttaaaataat ttttttttca gattaattga atatttcgac
       61 cacgtcatca atagaaatcg ctactactac ttacttaata caaatgatga atatagatca
      121 acatcatcag cttcaacagc aacatcaaca acaaatgtta caacaacaag ctcaggctca
      181 ggctcaggct caagctcaag cacaacaaca acaacaggca gcagccgcag ccgcagcagc
      241 taacgctgca gctactactt cttcttcttc ccctcgtcaa gtttcattca acgtatctga
      301 tcattatcaa atattagaaa ttgttggaga aggagcatat ggaatagttt gttcagccat
      361 tcataaacca tcacaacaaa aagttgccat taaaaaaatt gaaccatttg aaagaagtat
      421 gttatgttta cgtacattac gagaattaaa attattaaaa cattttaatc atgaaaatat
      481 cattagtata ttagctatac aacgaccaat taattatgaa tcatttaatg aaatttattt
      541 aattcaagaa ttgatggaaa ctgatttaca tcgagtcatt agaactcaaa atttatctga
      601 tgatcatata caatatttca tttatcaaac tttaagagct ttaaaagcta tgcattcagc
      661 taatgtatta catcgagatt taaaaccact gaatttatta ttaaattcaa attgtgattt
      721 aaaaatttgt gattttggtt tagcaagatc aattgcttca caagaagata attatggatt
      781 catgacggaa tatgtagcta caagatggta tagagctcca gaaatcatgt taacttttca
      841 agaatatact actgctattg atgtttggtc agttggttgt atattggcag aaatgttgag
      901 tggtagacct ttattccctg gtagagatta tcataatcaa ttatggttaa ttatggaagt
      961 tttaggaaca ccaaatatgg aagattatta taatattaaa tctaaacgag caagagaata
     1021 tattagaagt ttaccctttt gtaaaaaaat tccgttcagt gaattatttg ccaataccaa
     1081 caacaatact agtactagta atactggcgg taggacaaat attaatccat tggcattaga
     1141 tttattagaa aaattattaa tttttaatcc tgctaaaaga attactgttg aagatgcttt
     1201 aaaacatcct tatttacaat tatatcatga tcctaatgat gaaccaatta gtgataaaat
     1261 cccagaagat tttttcgatt ttgataaaat gaaagatcaa ttaacaattg aagatttgaa
     1321 aaaattgtta tatgaagaga ttatgaagcc attataaaga ggtcaagcta agttaagcta
     1381 aactaaacta aactaaacta aactaaaaac tataggttgg gcttggtagt tgttgtagat
     1441 ttagcataat tgttgttgta taggttttga tttttgaatt tgtttttaca gttaaagtta
     1501 aagttgaagt taaagttaag taaacatgtg tgaagaatag attttgttga tatttgaaaa
     1561 gaaaaagaag tagaattaat gtaaaatatc tttaatactt tgataacact ggtaatatat
     1621 ttatgtctaa cttcttggtg tttagtcaat ttgttgatca cgtggataaa tttaagaatt
     1681 c
//