From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Hevea brasiliensis 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Date: 24 Jul 92 10:06:19 GMT
Distribution: bionet
Checksum: 37082     7

LOCUS       HEVHMGR3A    3507 bp ds-DNA             PLN       24-JUL-1992
DEFINITION  Hevea brasiliensis 3-hydroxy-3-methylglutaryl-coenzyme A reductase
            gene, 3' end.
ACCESSION   M74798
KEYWORDS    3-hydroxy-3-methylglutaryl-coenzyme A reductase.
SOURCE      Hevea brasiliensis (strain RRIM600) (library: Chye) DNA.
  ORGANISM  Hevea brasiliensis
            Eukaryota; Plantae; Embryobionta; Magnoliophyta; Magnoliopsida;
            Rosidae; Euphorbiales; Euphorbiaceae.
REFERENCE   1  (bases 1 to 3507)
  AUTHORS   Chye,M.-L., Tan,C.-T. and Chua,N.-H.
  TITLE     Three genes encode 3-hydroxy-3-methylglutaryl-coenzyme A reductase
            in Hevea brasiliensis: hmg1 and hmg3 are differentially expressed
  JOURNAL   Plant Mol. Biol. 19, 473-484 (1991)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     exon            <1..352
                     /number=1
                     /gene="hmgr3"
     CDS             join(<1..352,722..903,1152..1498,1922..2164)
                     /product="3-hydroxy-3-methylglutaryl-coenzyme A reductase"
                     /gene="hmgr3"
                     /codon_start=3
                     /translation="SLEGLPLDGFDYESILGQCCEMAIGYVQIPVGIAGPLLLDGKEY
                     TVPMATTEGCLVASANRGCKAIYASGGATSVLLRDGMTRAPVVRFPTAKRAADLKFFM
                     EDPDNFDTIAVVFNKSSRFARLQSVQCAIAGKNLYMRFSCSTGDAMGMNMVSKAVQNV
                     IDYLQNDFPDMDVIGLTGNFCADKKAAAVNWIEGRGKSVVCEAIIKEEVVKKVLKTNV
                     AALVELNMIKNLTGSAVAGSLGGFNAHASNMVTAVYIATGQDPAQNVESSHCITMMEA
                     VNDGKDLHISVSMPSIELGTVGGGTQLASQSACLNLLGVKGASKDSPGSNSRLLATIV
                     AGSVLAGELSLMSAIAAGQLVNSHMKYNRSAKDVSKITF"
                     /partial
     intron          353..721
                     /number=1
                     /gene="hmgr3"
     exon            722..903
                     /number=2
                     /gene="hmgr3"
     intron          904..1151
                     /number=2
                     /gene="hmgr3"
     exon            1152..1498
                     /number=3
                     /gene="hmgr3"
     intron          1499..1921
                     /number=3
                     /gene="hmgr3"
BASE COUNT      964 a    670 c    713 g   1160 t
ORIGIN
        1 gatccttgga gggactgccc ttagatgggt tcgattacga gtcaatattg gggcagtgct
       61 gcgagatggc aattgggtac gtgcagattc cggtgggaat tgctgggcca ttgttgctgg
      121 atggaaagga atatactgtg ccaatggcca cgaccgaggg ttgccttgtg gccagtgcaa
      181 atagaggatg caaggccatt tacgcatcgg gaggggctac ctccgtgttg ctgagggacg
      241 gcatgacccg tgctcccgtt gttaggtttc ccaccgccaa gagggccgct gacttgaagt
      301 ttttcatgga ggaccctgac aatttcgata ccattgccgt tgttttcaat aagttcgatc
      361 ctttcccctt ttccccctat ataaaagtaa agcgtcacct tttaaaatga ttatgagcca
      421 atttttacta aaatgcattt ttttttttga gatatcggta tagttggtaa atgttcaagt
      481 agtcatctat aaaaggggat ggactcttgc ttccatttta tttgacctgg ttttgctgtt
      541 ggcatttatt tgtttgcggt gattgtgatg ttgatggatt attcttttat attttgcttg
      601 aatcattctt tgcccacttc ctattataga ccacaacaat aatttcgtat tggcatttac
      661 catgaagaaa ataagtgagt tttaatttgt ttcattgatt aatttcataa atattatgca
      721 ggtcaagcag atttgcgagg ctacagagtg tccaatgtgc aatagcagga aaaaatttat
      781 acatgaggtt tagctgcagc acaggtgatg ccatggggat gaatatggtc tccaaagcgg
      841 tccaaaatgt catcgattat ctccagaatg attttcctga catggatgtc atcggtctca
      901 ctggtaaaac cctctggtct tcttctcagg cctctacatg caaaagattt gtacttatta
      961 actttaatca agtaataatt aaataatcct tagtaagcac caagatactg gattggctct
     1021 tgatgagttg gtttctttag aaataagttt agcgactaac aaattttcta tggttactaa
     1081 ttcaattgtc tgtctgttat atctctgctg gatagcgagt aaattttcta attgtgttat
     1141 gaatttatca gggaacttct gtgcggacaa gaaggcagca gcagtaaact ggatagaagg
     1201 gcgtgggaag tctgttgtat gtgaagcaat cataaaggaa gaggtggtta agaaggtatt
     1261 gaaaaccaac gtggccgccc tggtggagct taacatgatt aaaaacctta ctggctcagc
     1321 cgtagcaggt tctcttggtg ggtttaacgc ccatgctagc aatatggtaa ctgcagtata
     1381 catagctaca gggcaggatc ctgctcaaaa cgtggagagc tctcactgca ttaccatgat
     1441 ggaagctgtt aacgatggca aggaccttca catctcagtg tccatgcctt ccattgaggt
     1501 tattgaactt ttccatctta atttccatgc cttttggtat taatttagat catccatcaa
     1561 tcccatttat taaccattta gtagaaagca ttaacttgtt ttgtcactca tccacaagag
     1621 tttgatattt gcattctaat tcacattaat tataaataag tcatgacaga ataactcaag
     1681 agtgagtttg ttttgtttgg cctatttgaa tggaaaaata aataactcag aagttaagac
     1741 agatatagac ttctggcatg gcggatataa taagatgcca aagattcctt taaaactgta
     1801 cattttttgg aggatttcta aggtttaaag attagaaaat ggaataacgt ttaacttgag
     1861 ctctgaaatc aagatgtttt caaagttctt tattttttta aaatttatgc tacttgtgca
     1921 gctgggcaca gttggaggtg gtactcaact tgcatctcaa tcagcttgtc tgaacctact
     1981 tggggtaaag ggtgcaagca aagattcccc tggttcaaac tcaaggcttc tggcaactat
     2041 tgtcgctggt tctgttctgg caggggagct gtctcttatg tctgctattg cagctgggca
     2101 actcgttaat agccacatga aatacaacag atctgcaaaa gatgtatcca aaataacttt
     2161 ctgaagggta acacagctgc tttgtttagt tgagaaacta gaaataaatt atcaatcaag
     2221 tatatgtagc ataataatgg tcggcaactg ttgaggggga caaacaaaga aaagtccttg
     2281 tggaggaata tctttaaaat aaatggagcc cgctttgctg gtagatactg catttgatat
     2341 ccagagccat gtgagactgt tgggtctctt tccaagatct cttcactacc ctacaattgt
     2401 aagattttag ggtcaggggt tgccataaat tgtttatact tgctcttgat gtcatgaagc
     2461 cacctgaatg cccctagagg tttccagtgt tcggtatatt cctcctgcca accaaacttg
     2521 cgatctttct tgtattactc gtaattttat ttgttgttaa ttttgttgtg gtatgtatta
     2581 gtttaggaaa ggagatgttg taataggatt taagtctgtt tagatatgtg ttatctgttg
     2641 tttagctctg aatatgactc tatgaaatga aactttccat cagttggcct gtaatccacc
     2701 ctccccgtca cattgaagaa tcttaattgt ttcgtagtaa tcttatagta actcgatgat
     2761 atttgtaaca tccttaattt ttaaatttat tattttatga ataaatattg atattttatt
     2821 taaaatttag aaaattattt gaaatttttc agattttagt aatcggattc gatttttaga
     2881 aaatataaaa ttttgatgat ttttaaaaat taatttaaag attacgtggc aaaactaaaa
     2941 atatatttgg actctataaa tttttttgag ttttctagaa ttttttcgaa atttttgggc
     3001 ttcgttttcg atctcaatgc agagtaaaaa ttcaaaattt tgtattctga attggactgg
     3061 tcgaatcgaa ccagacctga tcgaactggt cgaatcggac tggccatctc tttttcttcc
     3121 tccttccgca ccgtccaaca cttcctcttc ctctcccgtt ttctctctcc tctctcctcc
     3181 tctcgccacg ccgctgccac cccagcttcc cccactagcc ggcgagccac tccagtccct
     3241 ccccgccaac ggctgacact ccaagccgtt ggaaaagtcg cgcgaaacct accctttgcg
     3301 tagcgcgcca tttcaccttc tcggccaaaa ttcggccgat ccggccacca attagaccgg
     3361 gtcttatgcc aaacctcatc tatacttcga gagctttcca tagacaccaa gaacaccaaa
     3421 atccatcgag cggtttatcc aatttttgtc tgggaagttt tagcatattt ggattttttg
     3481 gttaaatttc tcgcaaaccg tgaattc
//