From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens interferon regulatory factor 1 gene, complete cds.
Date: 6 Nov 92 18:06:49 GMT
Distribution: bionet
Checksum: 18500 13

LOCUS       HUMIFNRF1A   7721 bp ds-DNA             PRI       28-OCT-1992
DEFINITION  Homo sapiens interferon regulatory factor 1 gene, complete cds.
ACCESSION   L05072
KEYWORDS    interferon regulatory factor 1.
SOURCE      Homo sapiens Placenta DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 7721)
  AUTHORS   Cha,Y., Sims,S., Romine,M.F., Kaufmann,M. and Deisseroth,A.B.
  TITLE     Human interferon regulatory factor 1: intron/exon organization
  JOURNAL   DNA Cell Biol. (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           join(1..219,1279..1287)
                     /gene="IRF1"
     exon            1..219
                     /number=1
                     /gene="IRF1"
                     /note="putative"
     intron          220..1278
                     /number=1
                     /gene="IRF1"
     exon            1279..1374
                     /number=2
                     /gene="IRF1"
     intron          1375..2737
                     /number=2
                     /gene="IRF1"
     exon            2738..2837
                     /number=3
                     /gene="IRF1"
     intron          2838..3629
                     /number=3
                     /gene="IRF1"
     exon            3630..3806
                     /number=4
                     /gene="IRF1"
     intron          3807..3915
                     /number=4
                     /gene="IRF1"
     exon            3916..3965
                     /number=5
                     /gene="IRF1"
     intron          3966..4072
                     /number=5
                     /gene="IRF1"
     exon            4073..4202
                     /number=6
                     /gene="IRF1"
     intron          4203..4385
                     /number=6
                     /gene="IRF1"
     exon            4386..4508
                     /number=7
                     /gene="IRF1"
     intron          4509..5039
                     /number=7
                     /gene="IRF1"
     exon            5040..5089
                     /number=8
                     /gene="IRF1"
     intron          5090..6247
                     /number=8
                     /gene="IRF1"
     exon            6248..6383
                     /number=9
                     /gene="IRF1"
     intron          6384..6669
                     /number=9
                     /gene="IRF1"
     exon            6670..7656
                     /number=10
                     /gene="IRF1"
     3'UTR           6795..7656
     CDS             join(1288..1374,2738..2837,3630..3806,3916..3965,
                     4073..4202,4386..4508,5040..5089,6248..6383,6670..6794)
                     /gene="IRF1"
                     /product="interferon regulatory factor 1"
                     /codon_start=1
                     /translation="MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKH
                     GWDINKDACLFRSWAIHTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKG
                     SSAVRVYRMLPPLTKNQRKERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDD
                     HSSYTVPGYMQDLEVEQALTPALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMP
                     STSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKE
                     EPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP"
BASE COUNT     1750 a   1946 c   2253 g   1772 t
ORIGIN      
        1 agagctcgcc actccttagt cgaggcaaga cgtgcgcccg agccccgccg aaccgaggcc
       61 acccggagcc gtgcccagtc cacgccggcc gtgcccgcgc cttaagaacc cggcaacctc
      121 tgccttcttc cctcttccac tcggagtcgc gctccgccct cactgcagcc cctgcgtcgc
      181 cgggaccctc gcgcgcgacc gccgaatcgc tcctgcagca gaggtgagta cgcctttgag
      241 gccggggcac cggcggcgtc gaataaaagg cgcgcggggc accaggaagt ggggggtcga
      301 aagctccagg ctggagactc gccggcgcgc ggcgtgtcgc ccgggcctcc gcgcgggctc
      361 cggggggcgc cggaggagct gcgagccgcg ggccgcggcg cggggagggc gggaccgggc
      421 gtggaccgcc cacccggacg aggctgccgg cgcccggcag ctttcgcaga tctgcgtgcg
      481 cgcagccgcc aggggcctgt aggtggcccg ctatgttcgt cccgcgcatc cacacgccgt
      541 gccggggacc gagtgtcagc ccacgcgtgg gcgcccagtg ctcccggctt tcggcggtcc
      601 cacgtccggc cccaggcgac aggttttggg ctccctgtgc tggtggcaag ggctgcttac
      661 tgcccaggtg gctggaggga atcgtgacta cggagactgc gggaagaggc gccacaggtg
      721 ttccttgggc cacttctcca gaggagggga aaccgggccg gaagggttag cgtcctggtc
      781 ttagcgttgt gggcgctgtg gctgtcagga aggcgtagaa tggattcagg ggcgcgggag
      841 ggggctgttc agggtgacgg ctagcccttt gctagctagt ggttacaact caagtcaagg
      901 gaatttcttc ttggcatcaa gcaaaagaag tccctccctt cccaaaggat ttgaattttg
      961 agcgaaaagt tctgaaatta gggtatctgt gcattttgtc tcttttcctg catatgaatc
     1021 ctgaagccat cacttgcatg cctgtctcct ccagagactg gctgggaggg gctgaaggaa
     1081 ggggcaaaag catttttgcc taagatgctg aaaaaatttg gagagcagtt ttattccagc
     1141 gcagctcccc tccgcactga gtgtagtacc tagcagctgg ctgaggtgag gggagggtaa
     1201 ctaagtgacc tcgggtgggc aggtcactgc ccaggtactg ttcaacagat tccagactgg
     1261 agcctctgtg ttctctttac agccaacatg cccatcactc ggatgcgcat gagaccctgg
     1321 ctagagatgc agattaattc caaccaaatc ccggggctca tctggattaa taaagtgagt
     1381 gtaactcttt gggttttcct gccactgttt taacccatgt acttctggag ggaccaaagc
     1441 ttcagatgca gctcaaaaag ggaagtgata acgggacaag caggtgtttc tcccagtggg
     1501 tcctgcatgc agggagtgtg cacggcccag cctgggcctc acttgcatga ctcctgcctt
     1561 cttcccttct tgaggtaggg cacccacctg aaggcacttc cagtttccag cagcaagact
     1621 ttccagcatc tgcagagctg gagttctgct ctcctctaag cgagaccctt acaaacatac
     1681 acagcactct gcagggctcc aatcgaacaa atagaagact gagaagtgga tgctgctggg
     1741 cagaaacgtg ctggcttagc agaggacaaa cgagttaatc ttgcaccagt cactctggcc
     1801 caagaagcct atagctggtg cacttggggc aacatagacc ctatagactt agtagcaatg
     1861 atagtatcat aataatagct aatgcttact gaacactccc tgtgtgcctg gcacctgcta
     1921 agtatgttat ttacattgtg tcatttaatc ctcgcagtag tcctgtgggt tagatcttac
     1981 taatgtcatc attttcagat aagtaaacag aggcactgag aggtagatca taagatcaca
     2041 caagaagtga tgaagccaag atttgaactt gaacggctcg actcagaaat ctttactgtt
     2101 aaccataagt gatataataa cagtaagacc ttagacttca tatttgtcac tgtgtcccta
     2161 cacatcctct ggtttttaat cctcaaaatt ttgttggata tgttttctca tttccgagaa
     2221 gagaaaactg aggggcaaag agatacagtg acaatgccag ggttacacag tgttcaccat
     2281 ccaagtctag cccagagctc cctcagtggt atgaccagga ccccctgtgt aagagcccat
     2341 gctcccaggt gtcctgagga gtcctttcta atggaagaag ttcttacttc catgtgggtg
     2401 cttacaagcc agagagaaac atcccagagc ttcaaaacca gggctttggg ggagggtgcc
     2461 ctgtgtgggt cctagcacat gtgtaacagg cagagggagg tctttgtgag ctaataatgc
     2521 tgcagctcat ccaaactagg tgtcctcctg agagatccag agtggtctgt ttaagccagc
     2581 ctcaagatgg gtgtccaagc cagatgtcag gggaaaaaag gggaagtcag ccttttctca
     2641 gacctgtctg gctgggcagg cctgggtctc agactcagcc ccaaagtctg tggtctctga
     2701 cctgacacag ccttatgtgt atgtgtgtat tgttcaggag gagatgatct tccagatccc
     2761 atggaagcat gctgccaagc atggctggga catcaacaag gatgcctgtt tgttccggag
     2821 ctgggccatt cacacaggtg tgtgcctggg actcaggcct aggaagccca gggtagagac
     2881 aagaggaggc actcacgtta acacagaggc tcttcactgg ggtccctgag ctccctgaga
     2941 caacatgcag aattactggg aagaggggct ggtggcagac ttgtgtttct ggagaagaga
     3001 gtcgatcatc tcagcaaatt ctcaaaggga aaagccaaga tcttagaaag tgtgtggctt
     3061 cagggggttt gtggctagat gaaagttctc cctggcaaaa gcatctgtga aaagcagctg
     3121 taagccaggg cactgaaaga gacccaggtc tgcctttttc ttcgtgttga ccaaggccct
     3181 tggtccaagc ctcatgtggt tggtggcctc cttatccttg agagatggag ctctaggccc
     3241 atctcagaac agtcagccca cccatttagt aactgttctc tgctgcccag tctgtgccca
     3301 ctctaccctc tggctgctga tagcccaagg aggaagactg ggcatagtct gagacacaga
     3361 tagtacactt tggggatatg gggactctag tgcttctggc tgggcccttc actgaggccg
     3421 ctagatgtgt ttaagccaag cctgggcatt tgagaaggcc cagggcctag gacctgcaga
     3481 gtgtcaccgg gagtacctgc tggtttgacc actgtggctc tctggtagca taagaggtca
     3541 ggggtacctt gccttcctcc ttcagccagg ggcagctgag gatccctacc catggccctg
     3601 acgatcctct tttttctcct gccctctagg ccgatacaaa gcaggggaaa aggagccaga
     3661 tcccaagacg tggaaggcca actttcgctg tgccatgaac tccctgccag atatcgagga
     3721 ggtgaaagac cagagcagga acaagggcag ctcagctgtg cgagtgtacc ggatgcttcc
     3781 acctctcacc aagaaccaga gaaaaggtat ccaaggactc tgggtccttg ggaagccctc
     3841 agggagggag ggtagaagga ggtcagctgg ggctggagag cctgcaccaa ggctgacagc
     3901 ccgtctgccc cacagaaaga aagtcgaagt ccagccgaga tgctaagagc aaggccaaga
     3961 ggaaggtgag tgtggtccta agcagccagg cctttggtca cctgtgggcc agggtgagca
     4021 gtggaagaaa tgctaaggtg gcctgggcct aagctgcttt ctccctcgac agtcatgtgg
     4081 ggattccagc cctgatacct tctctgatgg actcagcagc tccactctgc ctgatgacca
     4141 cagcagctac acagttccag gctacatgca ggacttggag gtggagcagg ccctgactcc
     4201 aggtgagctg gtccaggtct ggcaggagac cccacaggtc agtgggatga ctctttctct
     4261 tggaggcatg gtgctggcac atggtggccc attagtgcag gctgcagggt tggtcggagg
     4321 gcgctcgatg tcttgcaaac taagaaagca cacaaccttg acctgtggct tctgctgttc
     4381 cccagcactg tcgccatgtg ctgtcagcag cactctcccc gactggcaca tcccagtgga
     4441 agttgtgccg gacagcacca gtgatctgta caacttccag gtgtcaccca tgccctccac
     4501 ctctgaaggt tggtgctcct ggggcctggc ctgctgcttg actgtctggg tctgtgaagg
     4561 gcttcctgag agagaaaaga tgatcagaac tccacctggc actgaattga ttgagttggg
     4621 cattgcagtc ttagccacca tagggggagg caagcgacgg ggacactagg aaggcagttc
     4681 agagtgggct gcagtacagt gggggctggt gagaggaggg aagggggcca ggggtgcatt
     4741 ttgggtgtgc tggttctcct tcctcctctg tagcccagca tcgtggaggg tgaggaagga
     4801 agtagggtag gggtgggaag cggcgtggct tcagggtttg agaggctgag tcaccaggcc
     4861 agggtcctgt tctggaatct ctatggcaga taggtccacc gggagggtgt gtgtgtgtgt
     4921 gtgtgtgtca gagagacaga gagacagaga aagggcaggg ggatctggtg ggctggaact
     4981 ggaactgcag ggtgagtgtg ctgactgcca gccaacctct ctgctttccc catccacagc
     5041 tacaacagat gaggatgagg aagggaaatt acctgaggac atcatgaagg taaagcccct
     5101 tcctacctgg gcactcttga agtgaccgtt tctcagtgag gagagagaac cagtgaagcg
     5161 ttccaaatca gaggatgggt agctgctgtt gtcacctggc tgcttgcatt gtcccacaag
     5221 tgccacattc acgtggcttg actggtggga aacccaccat gggaaggcag gtgggaggcc
     5281 tggcctctga cagcgtcctg aagcaagcct tggggcatca gacagctctg tgagtcaggc
     5341 actatcagcg atgggtccct ggcctgcatc ctctgcccca acatgcccca gccctgctag
     5401 ttcgggaaat gcacatcagg cttcaataat cagcctttag gatccgttaa tatgatgatg
     5461 gctttataga aaaagttagc aaattatcct ccaggttttt ttttctgctt cagttttgaa
     5521 agtgaatata gtttttgcag ccgggggcag tgctcatgcc tgtaatccca gcactttgga
     5581 aggcgaaggt gggtggatca cctgaggtca ggagtttgag accagcctga ctaacatggt
     5641 gaaacccatc tctaccaaaa atataaaaat tagctgggcc tggtgcgcat gcctgtaatc
     5701 ccagctactc tgaaggctga ggcaggagaa tcgcttgaac ctgagaggcg gaggttgcag
     5761 tgagctgaga ttgtgtcatt gcactccagc ctgggcaaca agagcaaaac tccatttcaa
     5821 aaaaaagttt ttgcagtagt tgtacgccag ctgttccatt agcccaaaaa attgagacat
     5881 ggatgtcgtt ccttatctct agcttttcta gtcatctttt cttgatttat tatgctaacc
     5941 tttgttttaa gccacattcc ctcttactat gtccttacac agttgagagg gaagtcgtgg
     6001 agatgctata ccagagagtg ggtgtgagag gggtgggaaa atgaattgag gaccagtgcc
     6061 aacatgcatt tctgcctcct ctcccgggcc cttgtcctga ctgcagtgca cttctgcatc
     6121 ctatctgaga ttgtgaaaat ggccaagggt gtgatactgg ctgagaggag ctggctcatt
     6181 gaggcagggc cacagggtga gtctgcactg gaagggagtt gatagcctct tgctcttctg
     6241 tccccagctc ttggagcagt cggagtggca gccaacaaac gtggatggga aggggtacct
     6301 actcaatgaa cctggagtcc agcccacctc tgtctatgga gactttagct gtaaggagga
     6361 gccagaaatt gacagcccag ggggtaagaa ggccctggat ccttatggct tcttagatga
     6421 gggagaacca cgtagggatg gagaaagctt gggggcaggg ccagggagca gggcggtaaa
     6481 gcatctgggg tactgacaca ttgtgaatta gctacggctg ccatgcctta aggtttgcct
     6541 gaagctgagt ggatgtttac tgctgtgctg ggaagagcag aggccatgtc tatggccttc
     6601 aggggtaggg ggaagcacac ctgatgccac cgtcccctac cctcatacaa ccttcttcac
     6661 atcttctagg ggatattggg ctgagtctac agcgtgtctt cacagatctg aagaacatgg
     6721 atgccacctg gctggacagc ctgctgaccc cagtccggtt gccctccatc caggccattc
     6781 cctgtgcacc gtagcagggc ccctgggccc ctcttattcc tctaggcaag caggacctgg
     6841 catcatggtg gatatggtgc agagaagctg gacttctgtg ggcccctcaa cagccaagtg
     6901 tgaccccact gccaagtggg gatggggcct ccctccttgg gtcattgacc tctcagggcc
     6961 tggcaggcca gtgtctgggt ttttcttgtg gtgtaaagct ggccctgcct cctgggaaga
     7021 tgaggttctg agaccagtgt atcaggtcag ggacttggac aggagtcagt gtctggcttt
     7081 ttcctctgag cccagctgcc tggagagggt ctcgctgtca ctggctggct cctaggggaa
     7141 cagaccagtg accccagaaa agcataacac caatcccagg gctggctctg cactaagaga
     7201 aaattgcact aaatgaatct cgttcccaaa gaactacccc cttttcagct gagccctggg
     7261 gactgttcca aagccagtga aatgtgaagg aaagtggggt ccttcggggc gatgctccct
     7321 cagcctcaga ggagctctac cctgctccct gctttggctg aggggcttgg gaaaaaaact
     7381 tggcactttt tcgtgtggat cttgccacat ttctgatcag aggtgtacac taacatttcc
     7441 cccgagctct tggcctttgc atttatttat acagtgcctt gctcggcgcc caccaccccc
     7501 tcaagcccca gcagccctca acaggcccag ggagggaagt gtgagcgcct tggtatgact
     7561 taaaattgga aatgtcatct aaccattaag tcatgtgtga acacatagga cgtgtgtaaa
     7621 tatgtacatt tgtcttttta taaaaagtaa attgtttata aggggtgtgg cctttttagg
     7681 aagagaaatt taacttgtag gaatgatttt actttttatg g
//