From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens factor VIII (F8C) gene, exon 16 through exon 20.
Date: 29 Dec 92 20:56:18 GMT
Distribution: bionet
Checksum: 23811 8

LOCUS       HUMFAC15     5031 bp ds-DNA             PRI       11-DEC-1992
DEFINITION  H.sapiens factor VIII (F8C) gene, exon 16 through exon 20.
ACCESSION   M88642
KEYWORDS    coagulation factor; factor VIII.
SEGMENT     15 of 21
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5031)
  AUTHORS   Gitschier,J. and Wood,W.I.
  TITLE     Sequence of the exon-containing regions of the human factor VIII
            gene
  JOURNAL   Hum. Mol. Genet. 1, 199-200 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            1051..1263
                     /number=16
                     /gene="F8C"
                     /evidence="EXPERIMENTAL"
     exon            1550..1778
                     /number=17
                     /gene="F8C"
                     /evidence="EXPERIMENTAL"
     exon            1986..2168
                     /number=18
                     /gene="F8C"
                     /evidence="EXPERIMENTAL"
     repeat_unit     2595..2879
                     /rpt_family="Alu"
     exon            3904..4020
                     /number=19
                     /gene="F8C"
                     /evidence="EXPERIMENTAL"
     exon            4627..4698
                     /number=20
                     /gene="F8C"
                     /evidence="EXPERIMENTAL"
BASE COUNT     1466 a    971 c    927 g   1667 t
ORIGIN      
        1 aagcttttag acagtttctt ttttcactat ataaataacg ctgtaatcac aacagttttt
       61 ctaagataaa attccagaag tgcaatgtat ttgagcatct taagagtttt tcttattaat
      121 tatttggtaa tgtcccttgc acatttgtct ttcatggagg aagtgctttt cttattgatt
      181 atgttacctt atatattaga tagtaaacca ctgaacattt taatgagagg tactttttca
      241 agtttttgtt ttctcttaat tttataaatg atggtttttg aaataaaaca ggttttaatt
      301 tttaggtagt aacccatcaa tctttacttt ttgacacttt cattgctttt atgtttataa
      361 aaattcctgc ctatccagag attttttaaa aaacacctat actttcctca gtttttctct
      421 tacagtttaa ttttttacat ttaacttttt aatacttcct gtagactaaa gttattttgg
      481 tgcattgtgt gaaccaagat caagtagttt attttttctg aaatatctat gctgttcaat
      541 taattgatgg tgtatattaa ggatgtagaa ggatctaaaa ttatggaatg tgggcaattt
      601 tgccttacat tttattttac tttccattat attctatgat aaatatgtat aatttttaat
      661 ctggaaagta agcctttttt aaaagataat atgcattcat tctagaattt gtcatgaaga
      721 accttaactt acatatcaac tcctggcgtt atggtctctt ataacccctg cagtaacatt
      781 ttccctttta ctctggaatg gcttttatgt gtttaggaat tttctccttt gcaactttga
      841 gttcatacct taaatttaga atacaaaacc tcctcaggat taggtttgag ttctaacagc
      901 atccatcttc tgtaccactt cttccagggt attaaaaact ttgataaaga ccaaaagaca
      961 ggtatttctt ttagggatgt aaaccctaag gaccttaaga tcctagaaga ttattcttgc
     1021 tttttttttt ttgtcgttat tgttctacag gtaactttca gaaatcaggc ctctcgtccc
     1081 tattccttct attctagcct tatttcttat gaggaagatc agaggcaagg agcagaacct
     1141 agaaaaaact ttgtcaagcc taatgaaacc aaaacttact tttggaaagt gcaacatcat
     1201 atggcaccca ctaaagatga gtttgactgc aaagcctggg cttatttctc tgatgttgac
     1261 ctggtaagca ggtgtctatt gtgctgacca ctttttggtt taaaagaaat ggtctttgtg
     1321 tactaagaat tttgatattt atcctacgtg caataagaag ctttaaatag gagagttgat
     1381 cattatattt gtgttttaga aatgtcattc tggaatctac tgaagaggat ggattatatt
     1441 tttggaaggt gggaggcagg ttggactggc ataaaaattg atgagaaatc cactctggtt
     1501 cataggtgag agagcttata ctcataggat tgatgtcttc cctccctagg aaaaagatgt
     1561 gcactcaggc ctgattggac cccttctggt ctgccacact aacacactga accctgctca
     1621 tgggagacaa gtgacagtac aggaatttgc tctgtttttc accatctttg atgagaccaa
     1681 aagctggtac ttcactgaaa atatggaaag aaactgcagg gctccctcga atatccagat
     1741 ggaagatccc acttttaaag agaattatcg cttccatggt aatatattcc acatccaaac
     1801 attatcactg tgaaatgcag attgcacttt gacaaatgag acttgatcca gggacttgaa
     1861 cattgtattt atttagagta tatctgtggg agtggaatcc tcatagatgt cagttttttt
     1921 ggtggagtgg agagaaagaa acttatataa tagattttaa caggcttctc tgtgtccttc
     1981 tccagcaatc aatggctaca taatggatac actacctggc ttagtaatgg ctcaggatca
     2041 aaggattcga tggtatctgc tcagcatggg cagcaatgaa aacatccatt ctattcattt
     2101 cagtggacat gtgttcactg tacgaaaaaa agaggagtat aaaatggcac tgtacaatct
     2161 ctatccaggt atgagcttgt ttgtgctctt tcttctacct actctatttg ttgagtactt
     2221 actttaaatg gtctaggcac tgggaacaca atcagtgatc aaagcagaca agctccatgc
     2281 tcttaagtaa tactttttca aatgcttttt aaaccatttg ttcaaagcaa atgaacaaga
     2341 taatttcaga tatagaaaaa ttgctaaaaa ggaaatagaa cagaataaat ggataattaa
     2401 tgtcacagta ctttcctagg gaaaaggaat ttattccttt atcatttacc atctcaaatc
     2461 ccatagggca ccagtagtca tccaaagagt catttgttta tgtatgtaac cagtatattg
     2521 attaagcact actcataatg ttgatcacaa cacaatttta ttttggttct tcactgtccc
     2581 tttaaaatag atttggccag gtgcgatggc tcacacttgt aatcccagca ctttgggagg
     2641 ccaaggttgg aggattgctt gaggccagga gttcaagacc agcctgggtg acaaagcaag
     2701 acccccatct ctacaaaaaa taattagcca gacatgtggt atatacctgt agtcccagct
     2761 acttcaccta cttgggtggc tgaagtggaa ggattgcttg agcccaggag gttgatgctg
     2821 cagtgagcta tgaaagtgcc actgcatcaa acttggacaa cagagcaaga ccctgtctct
     2881 aaaaaaaaaa aaccatccag tttaatagcg ggggtaaact ttccttattt cttcgtaaaa
     2941 attctgataa gccctgtaac ttttctgctc acccttaagt aataaacagg actaaagtca
     3001 ctttatgtca caaatacagt tcaaatcaga aattacaatg tccatcccaa gatattaatc
     3061 aaaattgtaa acttgattta acttcaatct cccctcctcc aacttgagcc tgcatcaggc
     3121 tggaagtctg cattggaaaa gggagacatg gttgagtcct ctgtttctgt accttgtgat
     3181 gatcgtgctt ccccacaacc cctttatagc tgctgttttg aactccaaca tggataggtt
     3241 aaaggtaagg ggataagata gttcttacct atttacagct ggcaccattg ttgtaaacta
     3301 gcttaacact gtttgtgcct ggcaatactt gttgactctt tctcctgcag ggcactttca
     3361 gggaactctt tagagactcc cttacgtgac tgtcatgaaa tccccttgac atgatttctt
     3421 ccacctttac tctgggtggt cacttgtgac tcatttctca gccctcagtg ttcacctgca
     3481 gcttcttgtt gctggggtaa ctttaccctt gtaggcagct ctagtggact ggatccagag
     3541 ggaactcacc ctgacttatc tgtttcacag agtccacatc tggccaatgg gaaacacacc
     3601 ttttgctcag aaagaccctg ggaatgtagg tcaatcataa tgagtagcat tctccttccc
     3661 aaccatcaaa gaattcactc accctgtttc tcatctgctg gggggagggg agtggtcaga
     3721 actcaatctc cacaaccccc aactgtaagg gtcacgtagc aagcactttg catttgaggg
     3781 gtccaaaagt agtggaacta ccaaatttgg taggtctact ctgatatttc gcataaacca
     3841 atgtatctca tgctcatttt ttagtgaaaa gaaataattt ctgttcctgt tggtttttat
     3901 aaggtgtttt tgagacagtg gaaatgttac catccaaagc tggaatttgg cgggtggaat
     3961 gccttattgg cgagcatcta catgctggga tgagcacact ttttctggtg tacagcaata
     4021 gtgagtagca atgtgggcag aggttcccta cctactcagc ctacttcttt acagctttct
     4081 tcctttctgg aatggttgct tgtgtcagga aataaataca agtttacatc attatcaaat
     4141 ttaaaatgaa tattgctggt agaaatcatc agagttctca gagtagggca gatatacttg
     4201 aagctttgaa cactttgtac ctgaagctct aaataattga caaaaaaaaa ataccacctc
     4261 atttttcaca acttggtaaa gctcgaagat ctccagtagc agatttttgg aatttaatgt
     4321 tgatttagtt accagataac ttagaaatac tacttggaag agtttggaga ttaaccctaa
     4381 acaagtaaga gagccactgg tctattatgt atggacccca gtttcttcag ctgtaaaatg
     4441 tgaatcattc tagcacctgt taggattaat taaatgaact aatacagtaa aacgttgagt
     4501 acagttcttg gcacatttaa acactaaaaa tagcatttgt tgacgttctc ccattttcat
     4561 tgacttacat ttgagaagct gaattttgtg cactctagtt actgtgttcc acccgtttca
     4621 tttcagagtg tcagactccc ctgggaatgg cttctggaca cattagagat tttcagatta
     4681 cagcttcagg acaatatggt aaatactatt atttttgctc caagaacctg ggctgattat
     4741 atcttttttt aataatctgg tggagaatct cagataatga atccatctcc atgcttctat
     4801 tagttctatt ccataagtgc ctctcaaata catctcctcc tctccacttc ccactgtggc
     4861 catcttaact caggtcacca tcatttctta cctgggcaat gacactgcct cttaaatatc
     4921 ctccctacct tcagtatttc ttccttgagt caattctttt cagtgcagca ggaagctata
     4981 ctttcctatg agcagtaatg gtaaagtttg actagggtct atagagaatt c
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