From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human ribosomal protein S6 gene, complete cds.
Date: 31 Dec 92 01:45:35 GMT
Distribution: bionet
Checksum: 41931 9

LOCUS       HUMRPS6B     4577 bp ds-DNA             PRI       18-DEC-1992
DEFINITION  Human ribosomal protein S6 gene, complete cds.
ACCESSION   M77232
KEYWORDS    phosphoprotein; ribosomal protein; ribosomal protein small subunit.
SOURCE      Homo sapiens (library: Stratagene cat.# 943202; Lambda DASH) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Lott,J.B. and Mackie,G.A.
  TITLE     Isolation and characterization of cloned cDNAs that code for human
            ribosomal protein S6
  JOURNAL   Gene 65, 31-39 (1988)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Heinze,H., Arnold,H.H., Fischer,D. and Kruppa,J.
  TITLE     The primary structure of the human ribosomal protein S6 derived
            from a cloned cDNA
  JOURNAL   J. Biol. Chem. 263, 4139-4144 (1988)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 4577)
  AUTHORS   Metspalu,A., Rebane,A., Hoth,S., Pooga,M., Stahl,J. and Kruppa,J.
  TITLE     Human ribosomal protein S3a: Cloning of the cDNA and primary
            structure of the protein
  JOURNAL   Gene 119, 313-316 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            311..357
                     /number=1
                     /gene="ribosomal protein S6"
     5'UTR           311..351
     intron          358..926
                     /number=1
                     /gene="ribosomal protein S6"
     exon            927..1058
                     /number=2
                     /gene="ribosomal protein S6"
     intron          1059..1626
                     /number=2
                     /gene="ribosomal protein S6"
     exon            1627..1837
                     /number=3
                     /gene="ribosomal protein S6"
     intron          1838..2030
                     /number=3
                     /gene="ribosomal protein S6"
     exon            2031..2177
                     /number=4
                     /gene="ribosomal protein S6"
     intron          2178..3883
                     /number=4
                     /gene="ribosomal protein S6"
     exon            3884..4041
                     /number=5
                     /gene="ribosomal protein S6"
     intron          4042..4146
                     /number=5
                     /gene="ribosomal protein S6"
     exon            4147..4279
                     /number=6
                     /gene="ribosomal protein S6"
     3'UTR           4243..4279
     CDS             join(352..357,927..1058,1627..1837,2031..2177,3884..4041,
                     4147..4242)
                     /gene="ribosomal protein S6"
                     /product="ribosomal protein"
                     /codon_start=1
                     /translation="MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEE
                     WKGYVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIV
                     DANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRK
                     PLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMK
                     EAKEKRQEQIAKRRRLSSLRASTSKSESSQK"
BASE COUNT     1284 a    856 c   1091 g   1344 t      2 others
ORIGIN      
        1 ggtaccgtca gatgcaaaag tgcctgggac agaagtgggg ctccgtggcg cccagctcca
       61 aaacccaggc agcgtggaaa agactagaca gggaaggggt tagccctcag aattacacgc
      121 gggtttgcct taccagacta ccaccactgg cacaacctca gacccacacc caaccgactt
      181 tacctcccag gccctgttaa tctcgcccgg aagtaccgcc cacccatgct cacttccgct
      241 atcccgtact tctgctcatc tcgcgagaac tgaaagcgcc tatgtgacct gcgctaagcg
      301 gaagttggcc ctcttttccg tggcgcctcg gaggcgttca gctgcttcaa gatgaaggta
      361 ggtgatggtg gcgagtgtta gactgggttt ggggaacgtg aatcgagtcc cagaacgcgg
      421 cattgcctca gttccagcac tccaggatcc tggctttagg tggagaaggg tctcaagtag
      481 gagaaggctc gcctttctgg ggcatggagc tttttggccg aacggatggc aggcgattgc
      541 ggctggagcc ggcgggccgg gagcgccatg gtggcgtccc cgcgcccagc cgggacggat
      601 gcggcgtgtt gcccagtttg cggcaggcct gtggtgcggc tcttgacccc ggctttcttg
      661 cttcgggagg gtgaacggct gcggagtgcc ctcgccccca gagtcattcc gcggggcttg
      721 aggggaaaac gtcctgctga gtgcggcgct tcttgactgc tactctgctt tcacgtgctt
      781 ttagtgagta cagtcggcat cttatatttc ctgcttgtgt ggaggcaaca tgaaaggctt
      841 tttgcagtgg aattaacttt gtagatggct ctacaattac ctgtatagat agtttcgtaa
      901 actatttccc cccttttaat ccttagctga acatctcctt cccagccact ggctgccaga
      961 aactcattga agtggacgat gaacgcaaac ttcgtacttt ctatgagaag cgtatggcca
     1021 cagaagttgc tgctgacgct ctgggtgaag aatggaaggt aaaagttgac aaattgttgc
     1081 aggtatttaa gtcagagacg gtaaacgcca ttggtaactg gtatttggaa tggggttcag
     1141 actccgggtt ctggcttctg acctttggta agttgcttcc gaatgccact ttataaagtt
     1201 agaggtatta ccttggaggg ggggacgtag agtaagccat aaaatatacg taaagtttac
     1261 atcaacataa ttcttgccct gcatcatgca tttggcaata tgtcacatag ctgtcctcat
     1321 aatccccaaa gtgccaaaaa gggttgtatc tgatttgttt gttgctgttt gatattttat
     1381 cttcttagtg ctgttatctc taataaaaca tcggttagaa atgcgacttg aaagacattt
     1441 gataattgaa cttgacaagt tgggaatata gacaaaactc actgaacaga gaaaacgtgc
     1501 ttaagttcaa attggttttc ataattatac tttctcatat aggtgtgttc acagaggtca
     1561 caatcctgta ctgtataatt ttggaataga aatagtaaat gtgtcattca ttgtatgctc
     1621 ttgcagggtt atgtggtccg aatcagtggt gggaacgaca aacaaggttt ccccatgaag
     1681 cagggtgtct tgacccatgg ccgtgtccgc ctgctactga gtaaggggca ttcctgttac
     1741 agaccaagga gaactggaga aagaaagaga aaatcagttc gtggttgcat tgtggatgca
     1801 aatctgagcg ttctcaactt ggttattgta aaaaaaggtg agggttactt gtgttcaatt
     1861 ttcgttgaaa ttgatttaaa gccagttgtc caaatgctta ttcatttgca gtatccagac
     1921 ttacagacca atggatttgt ttctctacca tcaattcaac attaaacatt ctgatttagg
     1981 attcttaagg aagttgttga attaaaatct cttcaactgt ttcttctaag gagagaagga
     2041 tattcctgga ctgactgata ctacagtgcc tcgccgcctg ggccccaaaa gagctagcag
     2101 aatccgcaaa cttttcaatc tctctaaaga agatgatgtc cgccagtatg ttgtaagaaa
     2161 gcccttaaat aaagaaggta ggagggatta tgcaattagg gcttgcttaa ttttggtaat
     2221 ttgtctatca ttttgtgtgc atatcagaag ataaatatgt gcctttggaa ggccttagca
     2281 ctattcactt ggagttttta cagaaaatat ttgggggtgg ccagcatacc cagttggtgt
     2341 taatccttgc ttattatatc cagtgccttg tagagtgcag taatttcgtt gaaaatctgc
     2401 ttgtgaatct ttgatgtata cattatccaa aaataacctg actttaaggt cattgctatc
     2461 tggtttagga gtcacatgtt tgagaattct gggactatta gcaccacaca ctttgtaatt
     2521 ttatatcaga tgttctaaat tattaatatt ttttaagaga tgaggtcaca ctgttgccca
     2581 ggctggtctt gaacccttga gctcaagtga tgctcccact ttggcttccc aaagtgctgg
     2641 gattatgggc gtgagcacca cacccagccc aaaattattt tttggcttac aaaagaagtt
     2701 gctttaaact tctgtttcat ctgtaggata tggataacaa tagttaagag ttgtgagaat
     2761 tagaagttag agaccttact cagaatacta gggagcaggt ggtagggatt tggagcttac
     2821 cttttaagaa ctttgttcca tatagtagac acatactcac cagtgaggac ctcaaatagc
     2881 aatatttctg tggtaaattt gggatattta tgttaaataa gcagcatgta cgtcaaggtt
     2941 gggttttcct gacaaaattt gaaagaattt ctctggattt tggttttcag gactggtgtg
     3001 acttaacata gatggcatag atagtatacg tctgttaagt cagtaattac acttacttga
     3061 gcacaggtac tgttcaaggt gctgagaata cagtatagac aaattcctcc cttatgaagc
     3121 tgatgttgca aaaaaaaaaa aaaagcaatt gacaaatagg tggcagttgc ccataatcat
     3181 agccctggaa ataatccgta taatacaagc gtggtctggt tgatgggtat ttttagatgg
     3241 ctagggagca ggtagtagga ggcttaacat tttagcagaa tctgaacatc tgagcattta
     3301 gcctaaggca gttaactcct acaaagtgtc catgaaacaa atacatctga aaaggcctat
     3361 nctccaatgc agatctgtaa tccatgagca gttttggagt acagatcaga ttaatgaaga
     3421 tactttaaca acatcccacc taatctgatg ttaatagtta acgttacccc tgaattggca
     3481 ggaattgtca aaggaaatag agatgcaagc ttacatcaaa tttaaaagta tggcaggatg
     3541 attatgtaga taatgtgtta agtggttttc acagacaaat taactatgca cagttatata
     3601 ttaacataat gccactgtat tttagtaaaa ctggaaggta gtaaaagtta gcctggttat
     3661 tttcaggact tggtttccct tatattttta taatatttaa ccaatcttct agatttctgt
     3721 ggagggggaa aaagcatttt agaatagttc tgatttgatt ttaaaggcct cattataggt
     3781 tttcatagat gctgttaagc ttacgtttat ttctgatgtt tttaaagtag atgtggattc
     3841 taacaaacaa atattgaaat gattgagtcc tttgaatttt taggtaagaa acctaggacc
     3901 aaagcaccca agattcagcg tcttgttact ccacgtgtcc tgcagcacaa acggcggcgt
     3961 attgctctga agaagcagcg taccaagaaa aataaagaag aggctgcaga atatgctaaa
     4021 cttttggcca agagaatgaa ggttagtcta agatgatttg agggggtggg aggagttcga
     4081 cctggctttg gatttgcgtc tttaacccag aaaggcctta actgtttgct gttttgtttt
     4141 gtttaggagg ctaaggagaa gcgccaggaa caaattgcga agagacgcag actttcctct
     4201 ctgcgagctt ctacttctaa gtctgaatcc agtcagaaat aagatttttt gagtaacaaa
     4261 taaataagat cagactctga tctctgttga ctttycattg ctgatagaaa actacataaa
     4321 tgaagagagg gaaagttagg tcatagaaaa tggggatatg tatatatggt attccaatgg
     4381 tggataaagt cagacctatt gtgtgtggta gtggaagaca aggtcagtgt acaggggttc
     4441 ctttccaggg gatggggcgc acaggaggga ttctgagcat aagacacctg cctcttcaga
     4501 atggcatgga acttagggga aatgatgagg actattatct tttttatata gttattttga
     4561 ggaatatagc tcttaag
//