From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus carboxypeptidase E (CPE) gene, exon 1.
Date: 31 Dec 92 01:31:19 GMT
Distribution: bionet
Checksum: 45395 10

LOCUS       RATCPE01     5907 bp ds-DNA             ROD       16-DEC-1992
DEFINITION  Rattus norvegicus carboxypeptidase E (CPE) gene, exon 1.
ACCESSION   L07273
KEYWORDS    carboxypeptidase E; carboxypeptidase H; enkephalin convertase.
SEGMENT     1 of 9
SOURCE      Rattus norvegicus liver DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 5907)
  AUTHORS   Jung,Y.-K., Kunczt,C.J., Pearson,R.K., Dixon,J.E. and Fricker,L.D.
  TITLE     Structural characterization of the rat carboxypeptidase E gene
  JOURNAL   Mol. Endocrinol. 5, 1257-1268 (1991)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Jung,Y.-K., Kunczt,C.J., Pearson,R.K., Fricker,L.D. and Dixon,J.E.
  JOURNAL   Mol. Endocrinol. (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           5253..5462
                     /evidence="EXPERIMENTAL"
                     /citation=[2]
                     /note="5' UTR from pituitary-specific promoter"
     5'UTR           5257..5462
                     /evidence="EXPERIMENTAL"
                     /citation=[2]
                     /note="5' UTR from pituitary-specific promoter"
     GC_signal       5287..5293
                     /citation=[1]
                     /note="putative"
     misc_signal     5355..5360
                     /function="Initiator-like sequence"
                     /citation=[1]
                     /partial
                     /note="putative"
     5'UTR           5358..5462
                     /standard_name="Carboxypeptidase E"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
                     /partial
                     /note="5' UTR from major transcription initiation site"
BASE COUNT     1497 a   1347 c   1392 g   1671 t
ORIGIN      
        1 gaattctcgt cgtaagaagt ggtttgtgag tccttggttc cttgcttctc tctgcttctt
       61 ggccacctta gatgaacagc tttccttcac cacacttgcc caccatcatg ttgctgtcgt
      121 gccccagacc aaagcaatgg atgcagatga cttagtatct ctgaaagggt gagtcaactg
      181 tgcatatttt tctttcaaat tgttaacctc aggtatttcg tcacagtgat aaacaactga
      241 tttcgaatct cagttttgtt tcgggttttc cagtatggag atctctctct ataacataga
      301 gccaacttcc ctagaataag tgatgaagga cacacacaca cacacacatg cacacacaca
      361 cggggggggg ggagggaggg gaaggaggga agggggagga gaaataagat ggaaagctgc
      421 agtttttccg taatgatttt ggaagataca tgctatcgtg tcttttggct ttagttttgc
      481 agttcttgag agctaactca ggtctttatg tatgctagat aaataatttg ccacggagct
      541 aattcttcaa tgcaattctc atcatttctg ctttcttatg ttcatttgag tgagttacta
      601 agtcctgcct acatttccga tagagggaaa ttaagcctcg tgtcttcaaa tggaggggga
      661 tagagactct atgcccatca ctactctgta cagttgctcg ctctggcata tttcttagca
      721 gagttttttg ataatttcat attggaaatt tcggacttgc cacggtggaa atatttacat
      781 catgtagcac tgcaaaacct ctgaaatcaa gttgtttccc accaggtaac tacgaatcct
      841 tccccagcac acagctggac agctgtcaaa ctctatgcta acagactttc tgcggggtag
      901 ataaatggtg aacaggctat tgtaggaaga gagtaaaagt tacacacata gagagaaata
      961 gtttccgacc ttggtgagaa tagaagggac tctgaaagta ggggttgtga gagtttaagt
     1021 atgcaagaac agacgtctag aagtgacacc acgaaacaac aatgtctctt tcgacttctt
     1081 tttcctgttt gtaaagacat tttaaaatag caggttgaat ttaactatgg ttattcaaac
     1141 acattaaaga cttgcatgca agatatttta aaattccaca gtcacggatg agtaagtgta
     1201 ttcgtgaagc cacaaaggac taatgcctgc ttcaatagaa ctggtgcagc cgacccacat
     1261 gtaaaataac ccagaagtgc aaagacagac cacattctaa ttccttccag tcagtgtcct
     1321 agtctgtggt gtgtgccatc tctcaggttt gtgagatcat ttcaaacaga aaccttccag
     1381 aaccatagga ttttggactt gaaagggacc ttagcaagtg ttagcacatg cgtcactgtt
     1441 tcttagtgca cgggtttgaa tgagcaatgc ctccatagtc tcaagccttt ggacacttgg
     1501 tctccagcag gtggctctgt ttgggaagat tacagaacct ttgggaggta gaaccgtgac
     1561 aggggaagtg catcactgta aggcgggctt tgaacactca ccgttttgcc tcttccccgg
     1621 ttttctttct gcttctttta ggcggatgga aatgtgatct ctcagctccc tgctctggcc
     1681 atctcagcca cctgcatcag acctcctctg ctgtgacaga ctttcactgt ggaactgtaa
     1741 ggcagaatga acttttctgt aagcctcttc tgggtatggt attttgtcac agtaacaaga
     1801 aaattaacta atacaacaca tctggcagtt gaatattaaa attagaaatc tctgccactc
     1861 ctcttgtttg cttttgacag ggtctcatgt aacccaggtt tcaaactccg tgtagtgtag
     1921 actaagcgat agctcctggc tctcctgcct tcaccctcaa gtgctggagt tacgagcata
     1981 tgctaccata cttggtcgat tttctggtta aaatgaagaa tgttttaaaa attcatttaa
     2041 aaaaagattt aaaaatttat atgtgtgtat gtccaagtac ccaaggtggc cgggagggac
     2101 tgtcacattc cctggaactg caggcataag tgattatata ccactgatgt gggtgctggg
     2161 aatcaaaccc acgtcctctg gaggagcagg agacaccctt cccctccgag tcgtctctcc
     2221 gacagcccct aaaccaggta tgcctgagac ttaccccaga ctctgtgaat catgaaagct
     2281 tgaaaacacg tgtgtttaaa acatgtttca ttatttgaga ctttcaaata atgatttaaa
     2341 attattacta ttattattat gactgttgtt gttatgtata cctgtcctgc ctttgtacat
     2401 tatacaccat gtgcctgtct ggtacctgca gagatcagaa gagattgttg gatccccttc
     2461 aactattctt acagacagtt gtgagctaat cttgtggatg actgggaatt gaacctgggt
     2521 tcttctggaa gagcaacaca tgctcttaac tggtggacca ttggtctagc cctaagacat
     2581 acattttcta agttgctata tggttctctt atactgaaat actagagaat ggataaccta
     2641 accaactttc tttttccttc tacaggttag ggccacaaac atctacgatg tcagagaact
     2701 cttcaagtaa tagtacacag ctagtataat cccacttctt ttcttttaaa gtaaaaaaaa
     2761 aaaaacaaaa caaaacaaaa taaaaagtac ctcgtgaccc ttaaaggtaa cattttaaaa
     2821 gaatagtcag ccatgggaca agttaggact tcagtgagag gagtagttac gtgactgcta
     2881 cacacacaca gtagttgtgt gtgtgtagtt actagtcaat atgccccaac ccagccacaa
     2941 attagtgagg ttgctttcaa ttgctaactt aaaatcctaa ctgtatattt tgaagtcatt
     3001 ggttttagcc actctgtttt cttctctctg gttttccaag gttactcttt tggaaatgct
     3061 tttagaaacc taattatagc tctggtttca gacttctgaa ctaagaaatc aaatacaggc
     3121 tggttagagc ggaaagcatt ggggcttttt gttgctattt ttcataaagt tctgtctacc
     3181 tcaaggagga tgtcagatga aggctatcct cgcccccaaa aagccccacc ccctactcac
     3241 atctgtggta gcttattaaa gcagcaccta actataatac aagccagcac ttggaaggtt
     3301 ccagataaga aatcgggagt tcaaagctag tctcagatat atagtgagtt tgaggttagc
     3361 ctgggctaca tgagacccta tcttaaaaaa agcatctatg ctgctgtgcg agatgtagac
     3421 ccatcgattc gaaactaacc tccctgctag tgccttggca acctgtctgt tcatacactt
     3481 tgatttacct gcttgaggga gagtctcact atttagctta ggttagcctc aatcccggtg
     3541 tcctcccgct tcaggttctt gagttctggg actacaggcg agcgctatca tggctgtgtg
     3601 ctcctttaaa cttgtattta gatatgttta tgtccccatt tattactgca tatgtgaggg
     3661 tgtctatgga ggccagacat cagatccctg gagctggaga cgcagacgct gtgatcccct
     3721 ggttgtgggg gctgggaatt gaactcaggt gctctgtaag agtattgtgt gctctttact
     3781 gtgacgccgt ttctccaacc cctgaaacag taatattaat tttattttta aaattctcaa
     3841 cgtgagccga atgcctacag ttgctgccct ttttggttta cgtttgttcc ctgaacgtgt
     3901 gacagataat ttttagatgc ctccttcacc cagtgccagc aatatttcgt gccttaacta
     3961 tagcagtctg gttctcaagg ggtgggagtg gcctgggtgg gtggggtgtg ggcagccatg
     4021 actgccacag gtcggcttct gagggcagtg ggccttctga gaaccacaga ggccacccaa
     4081 cctgttgtcc tgctaacatg cactttcttt cttttttttt cccccccgga gctggggacc
     4141 gaacccaggg tcttgcgcat gctaggcaag cgctctacca ctgagctaaa tccccaaccc
     4201 ctgacatcac tttctaagca actgggttcc ctttgccctc tagctgcatc tgagaccaag
     4261 gagtcagaaa gagaaggtgc ttccacggtt tcaaacttca gtataaaaga aaaaaaaaaa
     4321 acctaatgaa attatttata gacctggatt cctttctagg tgacaggttt tattcaggac
     4381 agggtattat tagatagtgg agaaagaggc atctggggaa aaatgtccca catgaaacct
     4441 tcccctgctg gtgtgctgat cttttttttt tttttttttt ttttttggtg gccacgctca
     4501 atggattatt tgttcagatc catactggtg ttacatccaa tggcaactgt tgtagagtaa
     4561 catctgctgc agatgttgct ccaaaagtac agaccctgcc caagggtggt catttaagcc
     4621 cacgatttta tacccttgca gtcactttgt gaaagggaag acaatatcat ttatctgcat
     4681 cggtttttcc tccatcacag gattgaatca tactgccaaa cgaaatcctt tgtctaacgc
     4741 atgaacagag tctcgttggt gtttctcaga gtgtcacaga agatgagtgg tattggtctt
     4801 gcttgcttac ctcatttctc tctctttccc cctagaagga ttccggagta tgtctgaata
     4861 cagttaaaag cgctctctgt aaatgggtag aaagcagaat caaatcaaaa tacagtgttc
     4921 tggtttctag ccagaccttg ctgtaagatg aagccacaac ccttaagttt ccactattgc
     4981 agcagtaatg tccgagaaag aaggcaagct gtgggttgct tctcaccccc accccacatt
     5041 ctgatgcctc taggtggaaa tcaaaaggct ctgctagtaa cccaagaatg tgttttctac
     5101 aagggtgatc ctggtcgtgg ttccctctca ttcacaataa ccctcctaag ccaaggtctt
     5161 agctgtcatt ccacctgcgt ggtccctggc gccatttggc ttttgacgtg ggtctgagcc
     5221 aaggaataaa gccagcatcc tggcggttgt tccgcctgtg ccgggcctcc tgcctcctgc
     5281 tccccggggc gggtagtgca gcgcgcagag ccgtcgcgtc gccactgtcc tctgggtggc
     5341 cccagcgcgc accgttcatt gagccgtgga aggtgagacg agaggaggct ggtgctgagc
     5401 tcgccaactc cacccgggcc cgggcagaca aaagagaccg gcggtacagc tcgcgggacg
     5461 cgatggccgg gcgcggagga cgggtgctgc tggcgctgtg tgccgcgctg gtggccggcg
     5521 ggtggctgtt agcggctgaa gcccaggagc ccggggcgcc agcggctggc atgcggcggc
     5581 gccggcggct gcagcaggag gacggcatct ccttcgagta ccaccgctat cccgagctgc
     5641 gcgaggcgct ggtgtcggta tggctgcagt gcaccgccat cagcaggatc tacacggtgg
     5701 ggcgcagctt cgagggccgg gagctcctgg tcatcgagct gtctgacaac cccggggtcc
     5761 atgagcccgg taagtgcgct gcggggacgg gaaggaggag gagaggtggg ccccgagttg
     5821 ctgccgggtg gaggatgcct ggatgggaag tgggaaggaa acgaacgtca gcctctccat
     5881 cgttcgcatc ttcgacccgt ttttttg
//