From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human transferrin (Tf) gene 5'region.
Date: 24 Jul 92 10:07:37 GMT
Distribution: bionet
Checksum: 53694     4

LOCUS       HUMTFG5       724 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  Human transferrin (Tf) gene 5'region.
ACCESSION   X04600
KEYWORDS    TF gene; transferrin.
SOURCE      human (Homo sapiens).
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Lucero,M.A., Schaeffer,E., Cohen,G.N. and Zakin,M.M.
  TITLE     The 5'region of the human transferrin gene: structure and potential
            regulatory sites
  JOURNAL   Nucleic Acids Res. 14, 8692-8692 (1986)
  STANDARD  simple automatic
COMMENT
            [1]  enum. -620 to 104, no zero.
            *source: cell-type=leucocyte; See also $<$<STFRR>$>$for ccoplete
            coding sequence of human transfer (mRNA).  The human Tf gene is
            about 33.5kb long and is organized in 17 exons and 16 introns.
            Data kindly reviewed (25-APR-1987) by Zakin M.M.
               EMBL features not translated to GenBank features:
               key        from     to       description
               SITE          9     14       put. Sp1 binding site
               SITE         12     19       put. cis-acting enhancer region
               SITE         50     57       put. cis-acting enhancer region
               SITE        174    188       put. multiple metal binding
            regulato
                                            element (MBS)
               SITE        223    229       put. cis-acting enhancer region
               SITE        275    282       put. cis-acting enhancer region
               SITE        311    325       put. MBS
               SITE        390    404       put. MBS
               SITE        536    550       put. MBS
               SITE        574    579       put. Sp1 binding site
               PRM         594    598       put. TATA-box
               SITE        617    621       put. MBS
               TRANSCR     621   >724       primary transcript (Tf)
               MSG         621    713       exon 1
               IVS         714   >724       intron I
FEATURES             Location/Qualifiers
     intron          <1..713
                     /number=8
                     /gene="TF"
     mRNA            621..>713
                     /gene="TF"
     CDS             671..713
                     /product="transferrin"
                     /gene="TF"
                     /codon_start=1
                     /translation="MRLAVGALLVCAVL"
                     /partial
     intron          714..>724
                     /number=9
                     /gene="TF"
BASE COUNT      133 a    202 c    249 g    140 t
ORIGIN
        1 aagcttgagg gcgggaagtt ttccagccca ggagcctgag ctcagcgggg caggaagagg
       61 gagcagctcc tccgtggggg acctttgaga gcccaggagc aggatttcga gggacacctg
      121 gtggggagca aaaggtgctg agtctgtctt tgaccttgag cccagcttgt ttctcctgca
      181 tcctccccca aaagggcttt gcctgtcatt ctgcagttct agtgtggggt ctgggcgcag
      241 ttcttttccc tctccagcct cggagtcttc ctctgtggac tgcgcagata ggactggtgg
      301 cacggaccag ctctgcagcc tggagtcagg agcagagccc cggctccagc cgcgtagccg
      361 ctctggcacc gagcgagccg gatgacaatg gctgcattgt gcttcatgtc ccttcccatc
      421 aacatttctg tgctggactc cttccactcg cgggtcgtct ccagagctca gaaaatgagg
      481 tgatcagtgg gacgagtaag gaaggggggt tgggagaggg gcgattgggc aacccggctg
      541 cacaaacacg ggaggtcaaa gattgcgccc agcccgccca ggccgggaat ggaataaagg
      601 gacgcggggc gccggaggct gcacagaagc gagtccgact gtgctcgctg ctcagcgccg
      661 cacccggaag atgaggctcg ccgtgggagc cctgctggtc tgcgccgtcc tgggtgagtg
      721 cggg
//