From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human homeobox HOX 4A gene for homeodomain protein, complete cds.
Date: 3 Jan 93 22:15:36 GMT
Distribution: bionet
Checksum: 30956 10

LOCUS       HUMHOX4A     5834 bp ds-DNA             PRI       23-DEC-1992
DEFINITION  Human homeobox HOX 4A gene for homeodomain protein, complete cds.
ACCESSION   D11117
KEYWORDS    HOX 4A homeodomain protein; homeobox.
SOURCE      Human peripheral lymphocytes, cell line AKIBA, AKIBA genomic cosmid
            library, DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5834)
  AUTHORS   Taniguchi,Y., Fujii,A. and Moriuchi,T.
  TITLE     Cloning and sequencing of the human homeobox gene HOX4A
  JOURNAL   Biochim. Biophys. Acta 1132, 332-334 (1992)
  STANDARD  full automatic
COMMENT     Submitted (14-MAY-1992) to DDBJ by: Yasushi Taniguchi Dept. of Cell
            Biology Tokai University School of Medicine Bohseidai, Isehara
            Kanagawa 259-11 Japan Phone:  0463-93-1121 x2579 Fax:
            0463-91-1370.
FEATURES             Location/Qualifiers
     exon            <1408..1900
                     /number=1
     exon            3761..>4518
                     /number=2
     polyA_signal    5321..5326
     polyA_signal    5692..5697
     CDS             join(1408..1900,3761..4518)
                     /gene="HOX 4A"
                     /product="homeodomain protein"
                     /codon_start=1
                     /translation="MQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD
                     TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQ
                     PPPPPPTLPPCSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNS
                     CATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
                     ERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGL
                     AYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN
                     LQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHP
                     TYTDLSAHHSSQGRLPEAPKLTHL"
BASE COUNT     1427 a   1535 c   1468 g   1404 t
ORIGIN      chromosome 2.
        1 gtgatttgaa accaggtggg ggggagaccc tttttttttt tttttttttt taagttctgg
       61 ctgttctgag catgttatag gactttcatt tcccatcaaa accttgtgct gacccaatga
      121 ttgactgatt gatccactta ttaattcacc tattcaacaa gcatttattg cactaactac
      181 atgcagggca ctgtgctgga tgttaggaac agtagacaaa tgacacagcc cctgcctgca
      241 aggagcttac agtttagtgg gcgaatcagc caacaaaatg tctgaggcta taagtacttt
      301 tccacacaga agaaaggtaa atgggcaatc ttgaagaaag taaattgtat ctggaggtag
      361 agggaagccc tttccctcag ctacagttga gctaaaaaga aggaaactct tcttacattt
      421 aggaaaaatt ccttctgata cttccagagg ttcaaataag ttgaacttca taaaatctgc
      481 caggcgcagt ggctcatgcc tgtaattcca gcactttggg aggccaagac gggaggatca
      541 caagagccca ggaactcaag accagcctgg gcaacattgt aagaccctgt ctctacaaaa
      601 aaaaaaaaaa aaaaaactaa gagctggcgc agtggctcac acctgtaatc ccagcactta
      661 gggaggccca gcgggttgat cacctgaggt cagagttcaa gaccaacctg accaacatgg
      721 tgaaaccctg tctctactaa aaatataaaa aattagccag gtgtggtggc aggtgcctgt
      781 aatcccagct actcaggagg ctgaggcagg agaattgctt gaacccagag gcgtaggttg
      841 cagtaagctg agatcatgac actgcactcc agccttggca acaggagcga aattccatct
      901 aaaacaaaac aaaacaaaac aaaacactaa gacatgtagc caggcatggt gggcacctgt
      961 agctactgca gaatagctgg gactttgaaa tactctgaaa tagctattaa taccaggcta
     1021 aagtgggagg atcgcttgag cccagtaaat tgaggctgca gtgagccatg ttcatgccac
     1081 tgcactccag cctgggcaac aagcaagaca ctgtattaat aaataaatag ataagtaaat
     1141 aaactcagat ccagcacctt gcccatctcc ccgccgtgaa gtgggtagga agcagagagc
     1201 atgggctagt ccttctatat tgactggtct tgccaatgac actccctctg gggcctcttg
     1261 cttttcttct gacaggtcac ctggagcctg ggggccggcc cagctctctc aggattcagc
     1321 agacattgga ggtggcagtg aaggatacag tggtagtcaa tgttatttga gcagggtcag
     1381 caggccctgg agcttcctga gtgcacaatg cagaaggctg cttactatga aaacccagga
     1441 ctgtttggag gctatggcta cagcaaaact acggacactt acggctacag caccccccac
     1501 cagccctacc caccccctgc tgctgccagc tccctggaca ctgactatcc aggttctgcc
     1561 tgctccatcc agagctctgc ccctctgaga gccccagccc acaaaggagc tgaactcaat
     1621 ggcagctgca tgcggccggg cactgggaac agccagggtg ggggtggtgg cagccagcct
     1681 cctggtctga actcagagca gcagccacca caaccccctc ctccaccacc gaccctgccc
     1741 ccatgttcac ccaccaatcc tggaggtgga gtgcctgcca agaagcccaa aggtgggccc
     1801 aatgcttcta gctcctcagc caccatcagc aagcagatct tcccctggat gaaagagtct
     1861 cgacagaact ccaagcagaa gaacagctgt gccactgcag gtagctccct gaggtggcct
     1921 actgccagac caagccccct ccagattgac ccaaggaagc ctagtcaggg ctggaaatgc
     1981 aaccttggag gtcatatgtc taaactccta ctcacgtcaa aatgttcttt tttttagtgt
     2041 tcctgattgg ggtcatgacc ttgcagtgac agggtgctcc cttccattcc aggctgctgg
     2101 tgctgttgct ggacaggtct tatagctatt aatagagagt gcttccttat atgggcatat
     2161 ctgttttcct gggctgctaa ttataactcc attccctctt ccacccaaca gctcttcaag
     2221 atttgaagat aggtattaca atccccaagc ctaggtgatt atatagccca tatcacacga
     2281 atctcattcc cttaaactca taaaaactaa agtcttagaa agtaccatac taagtacttt
     2341 ctaagcatta tctaatttaa tttttcaaag aaccttttga ggtaggtata tgataacatc
     2401 cccattttac agataagaaa actgttagag aggataggca acttgcccaa gattctgaaa
     2461 ctgcaaagtg gtggatttga atccagtcag tctggcttta ggggctgcta agcataacca
     2521 tgagtctcta tttggccacc tcagcccaat tctcccactc cagcaaatcc ataatgggga
     2581 ggtgcctgtc ctagtaggag aggatattct gggagacagt aacagccttg gatttctcta
     2641 actggaaggg gagcccctcc agttgggcct tctctaggtc cacccagggc atgtagaaga
     2701 taggcatggc caggaactct gagggctgtt ccttctctct gcttagactg cttggttcct
     2761 gaaattttct gaccttgtgg tatctgatgt ggtttatctt caggtagatg aacttgcttc
     2821 caggtccagg gcaagtttgg ggcctggggt gtggcttgct atcagggatc tggtttgcct
     2881 gatgttttct ggggctgctg ctcctaggga gagggtatta tcctgcctgc aacctccttt
     2941 tcctgcccct ccttcctcag ctgcaggctc aggccctccc tcccaggaga aatccatttg
     3001 tcttccctgg gagggagtgg acaagcagct gagaggtggc agggtagtaa aagccagtgt
     3061 tgaggctgct gctcctagca ctgtgaatac tcaaaatgct tccagcctgg ccttggactc
     3121 cctaaaatac ccaggcagtg tttttttttg tttgtttgtt tggttggttt ttttttattt
     3181 tttatttttt tgtttgtcac ctccctggct ttgagtgcag ttgggctgca gtggggcgcc
     3241 aagatctcca tccccatact ttgctggggg ttggtggggg gctttgccca gaggccagct
     3301 cctaagcaag gcaggctgga gctatttcct cttcctttcc ttctccatac cccacccctg
     3361 gcagcagagg ctgggaggag tgttcaaagg agtctggccc ttctttgaca gagggaggcc
     3421 ttaccagctg ctcctggtct ctcattaaac tctttcatgg cctttgggtg ggtatgggtt
     3481 gatggactag gctgcagggg agagggtggg cagagtgaac tggatctcag aaggctgatg
     3541 gaggtttcag gtgcgactga taggtaggcc tagtaggggg ttggtaggta ggtgaattcc
     3601 cccttggaat catacctctc aaacggccct tcccctcccc agccaggatt ggaggtgggg
     3661 ggagggagga ggaaaagaga accagggaag cacccctctc cagtcctgag ggtccccacc
     3721 caactcactc agcgccctcc ctctctccct ccctgcccag gagagagctg cgaggacaag
     3781 agcccgccag gcccagcatc caagcgggta cgcacggcat acacgagcgc gcagctggtg
     3841 gaattggaaa aggaattcca cttcaaccgc tacttgtgcc ggccgcgccg cgtggagatg
     3901 gccaacctgc tgaatctcac ggaacgccag atcaagatct ggttccagaa ccggcgcatg
     3961 aagtacaaga aggaccagaa ggccaagggc atcctgcact cgccggctag ccagtcccct
     4021 gagcgcagcc caccgctcgg cggcgccgct ggccacgtgg cctactccgg ccagctgccg
     4081 ccagtgcccg gcctggccta cgacgcgccc tcgccgcctg ctttcgccaa atcacagccc
     4141 aatatgtacg gcctggccgc ctacacggcg ccactcagca gctgcctgcc acaacagaag
     4201 cgctacgcag cgccggagtt cgagccccat cccatggcga gcaacggcgg cggcttcgcc
     4261 agcgccaacc tgcagggcag cccggtgtac gtgggcggca acttcgtcga gtccatggcg
     4321 cccgcgtccg ggcctgtctt caacctgggc cacctctcgc acccgtcgtc ggccagcgtg
     4381 gactacagtt gcgccgcgca gattccaggc aaccaccacc atggaccttg cgaccctcat
     4441 cccacctaca cagatctctc ggcccaccac tcgtctcagg gacgactgcc ggaggctccc
     4501 aaactgacgc atctgtagcg gccgccgcca gcccgaactc gcggcaaaat tacctctctt
     4561 gctgtagtgg tggggtagag ggtggggccc gcggggcagt tcgggaaccc ccttccccgc
     4621 tcttgccctg ccgccgcctc ccgggtctca ggcctccagc ggcggaggcg caggcgaccg
     4681 ggcctcccct ccatgggcgt cctttgggtg actcgccata aatcagccgc aaggatcctt
     4741 ccctgtaaat ttgacagtgc cacatactgc ggaccaaggg actccaatct ggtaatggtg
     4801 tccaaaggta agtctgagac ccatcggcgg cgcccctgca gagggaccag agcttggaga
     4861 gtcttgggcc tggcccgcgt ctagcttagt ttcagagacc ttaatttata ttctccttcc
     4921 tgtgccgtaa ggattcgatc ggactaaact atctgtattt attatttgaa gcgagtcatt
     4981 tcgttccctg attatttatc cttgtctgaa tgtatttatg tgtatatttg tagatttatc
     5041 cagccgagct taggaattcg cttccaggcc gtgggggcca catttcacct ccttagggcc
     5101 cctggtctga actagttgag agagtagttt tgaacagtcg taaccgtggc tggtgtttgt
     5161 agttgacata aaggattaag accgcaaatt gtccttcatg ggtagagtca ggaagcccgg
     5221 tggcgtggca caacacactt tggtcatttc tcaaaaacca cagtcctcac cacagtttat
     5281 tgatttcaaa ttgtctggta ctattggaac aaatatttag aataaaaaaa tttcccagtc
     5341 agaagtgtat ctgtgttaat catgcacact tcgaagcaga tcactatgcc tttatctcgc
     5401 acaatcccca tggaaggccc cgaaacagac tgacactttg aaaaaaatat tttatttatt
     5461 tggagtctag tgcataaatt ggttctcggg atacttgatt actttccagc tattgaaatt
     5521 aggggagggg gaaatgagga tgcaaaccta agaaggttct gggcgggatg atttgggcag
     5581 ggctttttga aagcagcgcc tgctttgctg tttttactgc cttctttcta gacacaatcg
     5641 acttttacac tgggggcccc agagctcact tttctgcatt aagtaacaaa aaataaactt
     5701 tgaaagaaaa ctgacaatca aagaaaaaac acaagagaag ttgtaagaag aattgagcta
     5761 tgaaaaagct aaggtgtaga aaaagaaacc atcatttgga gacgcgtacc taagcttttt
     5821 ctctaggaaa tgct
//