From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mus musculus vascular cell adhesion molecule
Date: 8 Jan 93 05:49:11 GMT
Distribution: bionet
Checksum: 50359 5

LOCUS       MUSVCAMB     1342 bp ss-mRNA            ROD       07-JAN-1993
DEFINITION  Mus musculus vascular cell adhesion molecule
            phosphatidylinositol-form mRNA, complete cds.
ACCESSION   L08431
KEYWORDS    phosphatidylinositol-form; vascular cell adhesion molecule.
SOURCE      Mus musculus (strain FVB) (library: lambda GT10) adult lung cDNA to
            mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Hession,C., Moy,P., Tizard,R., Chisholm,P., Williams,C., Wysk,M.,
            Burkly,L., Miyake,K., Kincade,P. and Lobb,R.
  TITLE     Cloning of murine and rat Vascular Cell Adhesion Molecule-1
  JOURNAL   Biochem. Biophys. Res. Commun. 183, 163-169 (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1342)
  AUTHORS   Gerber,L.D., Kodukula,K. and Udenfriend,S.
  TITLE     Phosphatidylinositol Glycan (PI-G) Anchored Membrane Proteins
  JOURNAL   J. Biol. Chem. 267, 12168-12173 (1992)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 1342)
  AUTHORS   Moy,P., Lobb,R., Tizard,R., Olson,D. and Hession,C.
  TITLE     Cloning of an inflammation-specific phosphatidyl inositol-linked
            form of murine Vascular Cell Adhesion Molecule-1
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..60
     sig_peptide     61..132
                     /codon_start=1
     mat_peptide     133..1050
                     /product="vascular cell adhesion molecule
                     phosphatidylinositol-form"
                     /codon_start=1
                     /citation=[2]
                     /note="location of C-terminal cleavage is hypothetical,
                     see citation"
     misc_feature    989..1342
                     /citation=[1]
                     /note="phosphatidylinositol linkage exon not found in cDNA
                     described in citation"
     3'UTR           1099..1342
     polyA_signal    1310..1315
     CDS             61..1098
                     /product="vascular cell adhesion molecule
                     phosphatidylinositol-form precursor"
                     /codon_start=1
                     /translation="MPVKMVAVLGASTVLWILFAVSQAFKIEISPEYKTIAQIGDSMA
                     LTCSTTGCESPLFSWRTQIDSPLNAKVRTEGSKSVLTMEPVSFENEHSYLCTATCGSG
                     KLERSIHVDIYSFPKDPEIQFSGPLEVGKPVTVKCLAPDIYPVYRLEIDLFKGDQLMN
                     RQEFSSEEMTKSLETKSLEVTFTPVIEDIGKALVCRAKLHIDQIDSTLKERETVKELQ
                     VYISPRNTTISVHPSTRLQEGGAVTMTCSSEGLPAPEIFWGRKLDNEVLQLLSGNATL
                     TLIAMRMEDSGVYVCEGVNLIGRDKAEVELVVQDGRMKSQITNGHQLTVHLMFAKSFY
                     FICYLCLYLAL"
BASE COUNT      381 a    282 c    303 g    376 t
ORIGIN      
        1 cacttttccc agacactttt cacgtggggc acaaagaagg ctttgaagca gagacttgaa
       61 atgcctgtga agatggtcgc ggtcttggga gcctcaacgg tactttggat actgtttgca
      121 gtctctcaag cttttaaaat cgagatctcc cctgaataca aaacgatcgc tcaaatcggt
      181 gactccatgg ccctcacttg cagcactacg ggctgcgagt caccattgtt ctcatggaga
      241 acccagatag acagcccact aaacgcgaag gtgaggacgg aggggtccaa gtccgttctg
      301 accatggagc ctgtcagttt tgagaatgaa cactcttacc tgtgcacagc aacatgtggc
      361 tctgggaagc tggaacgaag tatccacgtg gacatctact ctttccccaa ggatccagag
      421 attcaattca gtggccccct ggaggttggg aagccggtca cagtcaagtg tttggctcca
      481 gacatttacc cagtttacag gctggagatt gatctgttca agggtgacca gctcatgaac
      541 agacaggagt tttcttcaga agagatgaca aagtctctag aaaccaagag tttggaagta
      601 acctttactc ccgtcattga ggatattgga aaagctcttg tttgccgagc taaattacac
      661 attgaccaaa ttgattctac actcaaagaa agggagactg tcaaagaact acaagtctac
      721 atctctccca ggaatacaac gatctctgta catccctcca caaggcttca agagggtggt
      781 gctgtgacaa tgacctgttc cagcgagggt ctaccagctc ctgagatttt ctggggcagg
      841 aagttagata atgaagttct ccagcttctc tcaggaaatg ccaccctcac cttaattgct
      901 atgaggatgg aagactctgg agtctatgtg tgtgaaggag ttaatctgat tgggagagac
      961 aaagcagaag tggaattagt tgttcaagat gggagaatga agtctcagat tactaatggc
     1021 catcaattga ctgtacacct aatgtttgcc aagagtttct acttcatatg ttatctctgt
     1081 ctttatcttg ctctgtgagg aagctgaaaa actcagacgc aatataattc atcatttgca
     1141 tggggtcaaa tggttctttc tttcatttat atgctgttct taatttaaaa tcctatgcct
     1201 tttcaattgt agctaatttt ctctattttt aaaaattatt gaccaatcaa aactgcatgc
     1261 atacattggg tatggtgtga tatgtggtat atttatacaa tgtggaatga ataaatcaaa
     1321 gtatatactt cagtaagagc ac
//