From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens Ig germline lambda-chain gene variable region
Date: 6 Nov 92 18:06:56 GMT
Distribution: bionet
Checksum: 40198 4

LOCUS       HUMIGLVF      560 bp ds-DNA             PRI       28-OCT-1992
DEFINITION  Homo sapiens Ig germline lambda-chain gene variable region
            retinoblastoma subgroup I (IGLV), 5' end cds.
ACCESSION   M94116
KEYWORDS    germline; immunoglobulin light chain; lambda-immunoglobulin;
            variable region; variable region subgroup VL-I.
SOURCE      Homo sapiens (library: EMBL-3) retinoblastoma DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Daley,D.M., Olee,T., Peng,H.-q., Soto-Gil,R.W., Chen,P.P. and
            Siminovitch,K.A.
  TITLE     Molecular characterization of the human immunoglobulin V lambda-I
            germline gene repertoire
  JOURNAL   Mol. Immunol. 29, 1031-1042 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    75..547
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="IGLV"
     sig_peptide     join(75..120,231..241)
                     /gene="IGLV"
                     /codon_start=1
     exon            <75..120
                     /number=X
                     /gene="IGLV"
     CDS             join(75..120,231..538)
                     /pseudo
                     /standard_name="Humlv1042"
                     /product="immunoglobulin lambda-I V-region"
                     /gene="IGLV"
                     /codon_start=1
                     /partial
     intron          121..230
                     /gene="IGLV"
     exon            231..538
                     /number=X+1
                     /gene="IGLV"
                     /partial
     mat_peptide     242..538
                     /pseudo
                     /standard_name="Humlv1042"
                     /product="immunoglobulin lambda-I V-region"
                     /gene="IGLV"
                     /note="putative"
                     /codon_start=1
                     /citation=[1]
     misc_signal     541..547
                     /standard_name="recombination signal sequence-heptamer"
                     /gene="IGLV"
                     /note="putative"
                     /citation=[1]
BASE COUNT      104 a    175 c    159 g    122 t
ORIGIN      
        1 ggggcaggga gagatttggg gaggctctgc ttcagctgtg ggcacaagag gcagcactca
       61 ggacaatctc cagcatggcc tggtctcctc tcctcctcac tctcctcgct cactgcacag
      121 gtgactggat acaggtccag gggaggggcc ctgggaagcc tatggattct tgctttctcc
      181 tgttgtctct agaagccgaa taatgatgcc tgtgtctctc ccacttccag ggtcctgggc
      241 ccagtctgtg ctgacgcagc cgccctcagt gtctggggcc ccagggcaga gggtcaccat
      301 ctcctgcact gggagcagct ccaacatcgg ggcaggttat gatgtacact ggtaccagca
      361 gcttccagga acagccccca aactcctcat ctatggtaac agcaatcggc cctcaggggt
      421 ccctgaccga ttctctggct ccaagtctgg cacctcagcc tccctggcca tcactgggct
      481 ccaggctgag gatgaggctg attattactg ccagtcctat gacagcagcc tgagtggttc
      541 cacagtgctc caggcccggg
//