From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human ADP-ribosylation factor 3 gene, exons 2-5.
Date: 6 Nov 92 18:06:16 GMT
Distribution: bionet
Checksum: 16404 10

LOCUS       HUMADPRF02   5167 bp ds-DNA             PRI       28-OCT-1992
DEFINITION  Human ADP-ribosylation factor 3 gene, exons 2-5.
ACCESSION   M74493
KEYWORDS    ADP-ribosylation factor 3.
SEGMENT     2 of 2
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5167)
  AUTHORS   Tsai,S.-C., Haun,R.S., Tsuchiya,M., Moss,J. and Vaughan,M.
  TITLE     Isolation and characterization of the human gene for
            ADP-ribosylation factor 3, a 20-kDa guanine nucleotide-binding
            protein activator of cholera toxin
  JOURNAL   J. Biol. Chem. 266, 23053-23059 (1991)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            118..358
                     /number=2
                     /gene="ADP-ribosylation factor 3"
     intron          359..1196
                     /number=2
                     /gene="ADP-ribosylation factor 3"
     exon            1197..1307
                     /number=3
                     /gene="ADP-ribosylation factor 3"
     intron          1308..1524
                     /number=3
                     /gene="ADP-ribosylation factor 3"
     exon            1525..1649
                     /number=4
                     /gene="ADP-ribosylation factor 3"
     intron          1650..2192
                     /number=4
                     /gene="ADP-ribosylation factor 3"
     exon            2193..5092
                     /number=5
                     /gene="ADP-ribosylation factor 3"
     polyA_signal    2588..2593
                     /gene="ADP-ribosylation factor 3"
     polyA_signal    5073..5078
                     /gene="ADP-ribosylation factor 3"
     polyA_site      5092
                     /gene="ADP-ribosylation factor 3"
     intron          order(M74492:1537..1624,1..117)
                     /number=1
                     /gene="ADP-ribosylation factor 3"
     mRNA            join(M74492:1319..1536,118..358,1197..1307,1525..1649,
                     2193..5092)
                     /product="ADP-ribosylation factor 3"
                     /gene="ADP-ribosylation factor 3"
     CDS             join(211..358,1197..1307,1525..1649,2193..2354)
                     /product="ADP-ribosylation factor 3"
                     /codon_start=1
                     /translation="MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVT
                     TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNE
                     AREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCA
                     TSGDGLYEGLDWLANQLKNKK"
BASE COUNT     1019 a   1308 c   1310 g   1530 t
ORIGIN      
        1 ccctcaggcc tctccgtttg tcatgaatga actctagcca tgaccttggg aaattctatt
       61 tacttggaag tcctgacaag caaatgatgg tatgattttt acatttcctt tgtctaggat
      121 caagtcttcc ataccaggga ccaggccaaa accagactgc cactgcccct acttgggccc
      181 cactgtcccc agaaagcagc tgctgtgatc atgggcaata tctttggaaa ccttctcaag
      241 agcctgattg ggaagaagga gatgcgcatc ctgatggtgg gcctggatgc cgcaggaaag
      301 accaccatcc tatacaagct gaaactgggg gagatcgtca ccaccatccc taccattggt
      361 aagagcacag cttggatgtg ggctttcacg ccggcagctg aggcagggca gggacctatt
      421 cctggttccc caacctggcc tcttctcccc aggcaagtcc atacaatttc ccgggttcag
      481 aaaagagggc agtgttgttt agcttactac caggtgctga ggctgctgtt tgccacctaa
      541 cctggctctc cctgatgcgg gaacttccat ggcctggcac tcaacagctg ccctcaggca
      601 cggagttggt ttcttctctg tgttgtttgg aaagcaggta aaaggctttg atgttcctgc
      661 caaagcttgg aattacttgg gtttagatct ttggtggcca atcttggtta cagtttgctg
      721 aagggagttc tccctacatt tgctatgtag atggggtctc cagtcagcat tgtcagctgg
      781 ctctgctttg gggctccagg atgccagctt acttcccttt cttcacctct gcctctcagg
      841 ccccacatct tagctgaggc cgactctggt agccaaagta ccagagcagg gctgagtcat
      901 tttgtaggag ggagcaccaa agactgagtg gaaaagtcag gaaagttggc ccacgttacc
      961 caggcaactg tgaacctctc aaccaacttc ctcatcctct ttgacttctc ttaggttttc
     1021 attttggcct tcaggctgct aggttaacga ttatcaggtc tgaggaagcc ttagcttttg
     1081 ttccattgtt ggtgttatgg ccaccactgg gggaaagcag aaccaaactc cattgtggtg
     1141 gtgtttgcgg ggctagtgtt tgagccaagt ggccattgcc tgtttttttt ccaaagggtt
     1201 caatgtggag acagtggagt ataagaacat cagctttaca gtgtgggatg tgggtggcca
     1261 ggacaagatt cgacccctct ggagacacta cttccagaac acccaaggta tgctcaggcc
     1321 tagcgtgggt tggttgggta tgagcagaga gtgtggctgt ctttgttaat gggtggccaa
     1381 ctgttaccct gctgcagctc ctgggggcag aagaaaggga ggaaagggag caaatatttg
     1441 gagggtgtca ggcaggtgtg gtcttttggt tggggggagg gggttacctg tcatcttagt
     1501 gcagcccatg ctctgccttc ctagggttga tatttgtggt cgacagcaat gatcgggagc
     1561 gagtaaatga ggcccgggaa gagctgatga gaatgctggc ggaggacgag ctccgggatg
     1621 ctgtactcct tgtctttgca aacaaacagg tgagacttct tcccacccct gaatttggga
     1681 gaccagcaaa ctggctgtgg aaattgttgg ctcttgggcc tattatatgg ttaacccttt
     1741 tagtatgctc tcaatgttag aagcgtggaa aactgagcac ttggcttctt tatcccctct
     1801 tcttgtcccc accccaagct ttatttagca acatttcagt cctcaggaat tgtctcaaat
     1861 ctttctttca tcttgcctgt tatctacttt aggagaattg gcctcactcc tgctgtcaga
     1921 cagacctgat tctttggtca gtctgaatca cgtctcttgc ttgcccacca tcctcgtatt
     1981 ggttccaatt cttcagtaca gtgacctcta gtgcttggat cttgagttct aggtgactaa
     2041 atccaaagta gctcctatag gatcttgttc tgggtttcca aaaataaagg aggaggggaa
     2101 ggtgctggta cacatttctt tggtagatgg gtgttctaga agcctttaaa aaatcctgag
     2161 gcttcttttt atgtgtctcc cacgtgctcc aggatctgcc taatgctatg aacgctgctg
     2221 agatcacaga caagctgggc ctgcattccc ttcgtcaccg taactggtac attcaggcca
     2281 cctgtgccac cagcggggac gggctgtacg aaggcctgga ctggctggcc aatcagctca
     2341 aaaacaagaa gtgaaagcca gacagcccta acaaagcacc ccacccaccc ctgacatacc
     2401 tactgtcacc ctgccccagt cctacccctt cctctccatg caagtgtggc cagggccctg
     2461 ggtatcatgt ccacatgccc agcaagagcc ttgcctcccc tgcctcccct cctttttcct
     2521 gtccacctat atgaccaatc cctaattgct gtcctgatga tgagtcattc caatttactg
     2581 gatttaaaac aaaaagttgt tacggtttca tggggtggcc cctctctctc tctcacctct
     2641 gggtttcggg aggtcgagtg gggtattctc tttgtttggc agtggttgct gtcctcttgg
     2701 catctgagtc ctttccctgt ccccacaagc ccttctactc cctgtttgcc tttcctttgc
     2761 caccctctcc ctgttttaca tggaaattgc acgggcctct ctgtgtttgc gtgcatgtgt
     2821 gcgcctgtat atacatgtat agagagatat atttgtgggg gccgggggga gcggggaggg
     2881 ggtggagtga agctcagggc ttgcagccag gacactgccc actggagcct gtcatctgcc
     2941 ccttccgtgt tggtgagatt aagggaagaa ggtgggaggg cattagtcaa gccggactgc
     3001 cccagtcttt gactggttac cctcctctct gcaggtaggt ttttctggat gataggacag
     3061 atgatggatt cttcaccacc attttccttg tactcttctc tccacccttc ttagggctgg
     3121 aggatggcat ttatctctag atgactgttc ccaaggagat gccactctgc tctgccttac
     3181 tgttgggaag gagagaggaa cccactcact cttatcagct tagagtgttc aactgatcct
     3241 tccccaccat cttcagatct gttcctctgg agcttgactg gggggtgggg atggcaagtc
     3301 catggtgtgt gttagggacc cagggcattg ggggaaggga ggcgaaggcc tgaggttttc
     3361 catcttcatt ctcttttgtt attaggagaa ggtgaggcat gggccaatcc cattcctgcc
     3421 ttccagtgcc ccaccaccct tctgatctta ggggttggat gggtcatctg tccttggtca
     3481 gaattttctc accctagtac tcctactggc ctgaccaggg ctgactgggt attctaatga
     3541 ggagctggga agtggggtga catagctgac cttagtatca acccccctct tctccaactc
     3601 ttgttttcta gtccaggata tgctaaagga cgaagatttt ctattgtttc caggccctca
     3661 gaccatcctt gctgtccctt caccctccat gcccctgcca tcctcactca cttctcataa
     3721 atggatctgg gggttagagt ggaggaaata aaatcctgaa gtggttgtca gtgcttgtgg
     3781 gatgcagtgg tcttcaggat tctccccgca ttattatgta gttgttcaga agctgttgct
     3841 actgcgtctc tctgtctgca gggggcactt gttcctgagg tcctcgcctg ggtcctgact
     3901 tctgtagttt ctgtgaagac gtggctgtcc tgtgggctcc tgtgtgtgct ggctgcgcct
     3961 gagctccgag acagctgccc ataacctgct aaggtcaggg cccagggccc cccacagcat
     4021 ggctgaggga ccccttccca gtagggctgt cccaagcccc actccatggg gccaggtttc
     4081 ctggccactt ttgttgatag cagatggatc aatattagta accccatcca agattgaact
     4141 gtgaaagaga ggttccaggg gtatctccct cagtgccagt tacttagtga tgtgttaccc
     4201 aggatgcagc aggtgtgtgc aggtatcttg ctctctaggc ctgtgtgtgt gtgtgagtgt
     4261 gtgtgtatat gggtgtgggt gtgtttgtgt gtggtggttg tggggggggt gttggaggtt
     4321 ctatttcatt taaaaatgta ttcatttccc tggccccaca gatgcttccc tccatacttt
     4381 ttatttgctc tgtttcctca gatttatttt gtcttgcccc attgcctctc cttccttgaa
     4441 ctctttcctt ttcaatctca actcattcac tgctgttgct catttgccct tttccatgta
     4501 ttttttccta cttaggattt tccactctat ctttgtggtt catgaggact ttgcctcttc
     4561 tcctgcctca ttccctgact ttctctagtt agatgtcagt cctaaatagg ttttcctcac
     4621 ttcaggcctc acccctcacc ttgttttttt gggggctcca gggaccaatc tggggctgga
     4681 aatgttagga ggttgccttg gtgctgcccc agatctgtcc agcagggggc agtaagtgat
     4741 cttggtagta tccctggctg ctaagccctt ggcaggggtg gtcctttcta cattcccatt
     4801 cacttaacag ctcttttggg attgggtgtt tcattccatt tctgcccact ccctctcctc
     4861 tcctctctgg taggtttaat tttatgcttt ccctgattcc agctttctgc ttcctgagga
     4921 ctcccgctcc ccccacccca aagtttgtct gtggtgttat agtggtaact gcagttcctc
     4981 ctctggaatg tagactgtat atgtttaata actcaccttc tctatccttg ctcaaaatgt
     5041 gggataacgc gatgactgtg accctggttg gaaattaaac ttgttttatg cagctttgga
     5101 gccgaccttc atctttgctg tgcagcagcc gtgggacagt agtttcatgg tgaggggagt
     5161 cctgttt
//