From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: D.melanogaster Chc mRNA for clathrin heavy chain.
Date: 4 Sep 92 10:02:54 GMT
Distribution: bionet
Checksum: 51861    11

LOCUS       DROCHC       5610 bp ss-RNA             INV       04-SEP-1992
DEFINITION  D.melanogaster Chc mRNA for clathrin heavy chain.
ACCESSION   Z14133
KEYWORDS    clathrin; clathrin heavy chain.
SOURCE      Drosophila melanogaster RNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 5610)
  AUTHORS   Bazinet,C., Katzen,A.L., Morgan,M.M., Mahowald,A.P. and Lemmon,S.K.
  TITLE     The Drosophila clathrin heavy chain gene: Clathrin function is
            essential in a multicellular organism
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 5610)
  AUTHORS   Bazinet,C.W.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: strain=Canton S; *source: stage=adult head; *source:
            clone_library=Itoh et al, PNASU 83:4081-4085; *source: clone=cDNA6;
            *source: chromosome=X; *source: is_macronuclear=N; *source:
            is_proviral=N; *source: is_germline=N;
            From EMBL    entry DMCHC;  dated 30-JUL-1992.
FEATURES             Location/Qualifiers
     CDS             288..5324
                     /product="clathrin heavy chain"
                     /gene="Chc"
                     /codon_start=1
                     /translation="MTQPLPIRFQEHLQLTNVGINANSFSFSTLTMESDKFICVREKV
                     NDTAQVVIIDMNDATNPTRRPISADSAIMNPASKVIALKAQKTLQIFNIEMKSKMKAH
                     TMNEDVVFWKWISLNTLALVTETSVFHWSMEGDSMPQKMFDRHSSLNGCQIINYRCNA
                     SQQWLLLVGISALPSRVAGAMQLYSVERKVSQAIEGHAASFATFKIDANKEPTTLFCF
                     AVRTATGGKLHIIEVGAPPNGNQPFAKKAVDVFFPPEAQNDFPVAMQVSAKYDTIYLI
                     TKYGYIHLYDMETATCIYMNRISADTIFVTAPHEASGGIIGVNRKGQVLSVTVDEEQI
                     IPYINTVLQNPDLALRMAVRNNLAGAEDLFVRKFNKLFTAGQYAEAAKVAALAPKAIL
                     RTPQTIQRFQQVQTPAGSTTPPLLQYFGILLDQGKLNKFESLELCRPVLLQGKKQLCE
                     KWLKEEKLECSEELGDLVKASDLTLALSIYLRANVPNKVIQCFAETGQFQKIVLYAKK
                     VNYTPDYVFLLRSVMRSNPEQGAGFASMLVAEEEPLADINQIVDIFMEHSMVQQCTAF
                     LLDALKHNRPAEGALQTRLLEMNLMSAPQVADAILGNAMFTHYDRAHIAQLCEKAGLL
                     QRALEHYTDLYDIKRAVVHTHMLNAEWLVSFFGTLSVEDSLECLKAMLTANLRQNLQI
                     CVQIATKYHEQLTNKALIDLFEGFKSYDGLFYFLSSIVNFSQDPEVHFKYIQAACKTN
                     QIKEVERICRESNCYNPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQ
                     KYIEIYVQKVNPSRLPVVVGGLLDVDCSEDIIKNLILVVKGQFSTDELVEEVEKRNRL
                     KLLLPWLESRVHEGCVEPATHNALAKIYIDSNNNPERYLKENQYYDSRVVGRYCEKRD
                     PHLACVAYERGLCDRELIAVCNENSLFKSEARYLVGRRDAELWAEVLSESNPYKRQLI
                     DQVVQTALSETQDPDDISVTVKAFMTADLPNELIELLEKIILDSSVFSDHRNLQNLLI
                     LTAIKADRTRVMDYINRLENYDAPDIANIAISNQLYEEAFAIFKKFDVNTSAIQVLID
                     QVNNLERANEFAERCNEPAVWSQLAKAQLQQGLVKEAIDSYIKADDPSAYVDVVDVAS
                     KVESWDDLVRYLQMARKKARESYIESELIYAYARTGRLADLEEFISGPNHADIQKIGN
                     RCFSDGMYDAAKLLYNNVSNFARLAITLVYLKEFQGAVDSARKANSTRTWKEVCFACV
                     DAEEFRLAQMCGLHIVVHADELEDLINYYQNRGYFDELIALLESALGLERAHMGMFTE
                     LAILYSKFKPSKMREHLELFWSRVNIPKVLRAAESAHLWSELVFLYDKYEEYDNAVLA
                     MMAHPTEAWREGHFKDIITKVANIELYYKAIEFYLDFKPLLLNDMLLVLAPRMDHTRA
                     VSYFSKTGYLPLVKPYLRSVQSLNNKAINEALNGLLIDEEDYQGLRNSIDGFDNFDNI
                     ALAQKLEKHELTEFRRIAAYLYKGNNRWKQSVELCKKDKLYKDAMEYAAESCKQDIAE
                     ELLGWFLERDAYDCFAACLYQCYDLLRPDVILELAWKHKIVDFAMPYLIQVLREYTTK
                     VDKLELNEAQREKEDDSTEHKNIIQMEPQLMITAGPAMGIPPQYAQNYPPGAATVTAA
                     GGRNMGYPYL"
BASE COUNT     1459 a   1405 c   1411 g   1335 t
ORIGIN
        1 cgttagagct tgataagagc tcagtttgtc ttcagtgtgt gtgcccgtca tctagcaaca
       61 aaccgacgtg attatttcga ctaaacgttc caatggaaac cgaatcttaa accagaaacc
      121 gactaaactc gaacacaatt aaacaacaat aaatcctcga aacaaatcaa atacaaactg
      181 ttaccaagtg tgcaattcaa gaaaacatcg tattggcatt gttttcgcaa agatacattt
      241 acgttgtaaa ggtctgtcaa taactagacc tcactgtagt agtaaagatg acgcaaccac
      301 tgcccatccg ctttcaggag catttacagc tcacaaatgt cgggatcaac gccaattcat
      361 tttcattcag cacgctcacg atggaatcgg ataagtttat ttgcgtgcgg gagaaggtga
      421 atgataccgc ccaagtggtc atcattgaca tgaacgatgc caccaatccc acgcggcgtc
      481 ccatctcagc ggattcggct atcatgaatc cagctagcaa ggtcattgcg ctcaaagcgc
      541 aaaagacgtt gcagatcttc aacattgaga tgaagtcgaa gatgaaggcg cataccatga
      601 acgaggatgt ggtgttctgg aagtggatct cccttaatac gctagctctg gtcacagaaa
      661 cgagtgtgtt ccattggtcc atggagggcg attcgatgcc gcaaaagatg tttgaccggc
      721 attcatcgct gaacggttgt caaatcatca actaccgctg caatgcctcc cagcagtggc
      781 tactcttggt cggcatttcg gcactgccaa gtcgcgttgc cggtgccatg cagttgtatt
      841 cggtggagcg taaggtgtcc caggcgatcg aggggcatgc ggccagtttt gccacgttta
      901 aaatcgatgc caacaaggag ccgaccacgc tgttctgctt tgcagttcgt acggccactg
      961 ggggcaagct tcatattatc gaagttggtg ctccgccgaa cggcaatcag ccgtttgcca
     1021 agaaggctgt cgatgtcttc tttccgccgg aagcacaaaa tgatttccct gtggctatgc
     1081 aagtctctgc caagtacgac accatctact tgataaccaa gtatggatac atacatctgt
     1141 atgacatgga gacggccacg tgcatataca tgaatcgtat atcggccgat acgatctttg
     1201 ttaccgcacc gcatgaggca agtggcggca tcattggcgt caatcgcaag ggacaggtcc
     1261 tctccgtgac cgtcgacgag gagcagatca ttccctacat caacaccgtt ctgcagaatc
     1321 ccgatttggc ccttcgcatg gccgtgcgca acaatttggc tggtgccgaa gatctctttg
     1381 tgcgaaagtt caacaagctc tttacagccg gccagtatgc tgaagcggct aaagttgctg
     1441 ccctggcacc caaggccatt ctgcgtacgc cacagacgat ccagcgtttc caacaggtgc
     1501 agacaccagc tggctccacg actccgccgc tgctgcaata ctttggcatt ctcctcgacc
     1561 agggcaagct gaacaagttc gagtctctcg agctgtgccg tcccgtcttg ctgcagggca
     1621 agaagcagct gtgcgagaag tggctgaagg aggagaagtt ggaatgcagc gaggagttgg
     1681 gtgatctggt caaggcctcc gatcttacac ttgccctgtc catctatctg cgcgcaaatg
     1741 tgcccaacaa ggttatccaa tgctttgctg agactgggca gttccagaag attgtactct
     1801 acgccaagaa ggtcaactat acgcccgatt acgtgttcct gctgcgctcc gtgatgcgaa
     1861 gcaacccgga gcaaggagct ggtttcgcct ctatgttggt ggccgaggaa gagccactgg
     1921 cggacatcaa tcagattgtg gacatcttca tggagcactc catggtgcag cagtgcactg
     1981 cattcctgct ggacgccctc aagcataacc gtcccgccga gggtgccctc cagacgcgcc
     2041 tgctggaaat gaatctgatg tctgctccgc aggtggccga cgccatcctg ggcaatgcta
     2101 tgttcaccca ctacgatcgg gcccacattg cccagctgtg cgagaaggct ggactgctcc
     2161 agcgcgccct cgagcactac acggatctgt atgacattaa gcgggccgtt gtgcacacgc
     2221 acatgctgaa tgccgaatgg ctggtcagtt tctttggcac gctgtcggtg gaggactcgc
     2281 tggaatgtct gaaggcaatg cttacggcga atttgcgcca gaacttgcag atctgtgtgc
     2341 agattgccac caagtaccac gaacagctga ccaacaaggc actgattgac ctgttcgaag
     2401 gtttcaagag ctacgacgga ctgttctact tcctgagcag cattgtcaac ttctcacagg
     2461 atcccgaagt gcacttcaaa tacattcagg cggcatgcaa gactaatcag attaaggagg
     2521 tggagcgaat ttgccgtgaa tcaaactgct acaatcccga acgggtgaag aacttcttga
     2581 aggaggccaa gctgacggat cagctaccat taattattgt ttgtgatcgt tttgatttcg
     2641 tgcacgactt ggtgctttac ctgtatcgta acaatctgca gaagtacatt gagatctatg
     2701 tgcagaaagt gaatccatcc cgcttgccag tggtagtggg tggtcttctt gatgttgatt
     2761 gcagtgagga tataattaaa aatctaattc tcgtggtcaa gggacaattc tcaaccgacg
     2821 aactggtcga ggaggtcgag aagcgcaacc gtctcaagct tctccttccc tggctggagt
     2881 cccgagttca cgagggctgc gtcgagccag ccacccacaa cgcgttggcc aagatctaca
     2941 ttgactcgaa caacaatccc gagagatatc ttaaggagaa tcagtactac gatagccgtg
     3001 tggtcggtcg ctactgcgag aagcgggatc cccatttggc gtgtgtcgcc tacgagcgtg
     3061 gattgtgcga tcgcgagctg atcgccgttt gtaacgagaa ttctctgttc aagagcgaag
     3121 cacgctactt ggttggtcgc cgcgacgccg aactctgggc cgaggtcctt tcggagagca
     3181 atccatacaa gcgccagttg atcgatcagg tggtacagac cgctttgtcc gagacccagg
     3241 atcccgatga catctcggta acggtcaaag cattcatgac cgccgatttg cccaatgagc
     3301 tgatcgaact tctcgagaag attattctgg actcgtccgt ctttagcgac catcgcaatc
     3361 tgcaaaactt gctcattctc acagccatca aggctgatcg cacccgagtc atggactaca
     3421 ttaaccggct ggagaactac gatgcaccgg acatcgcgaa cattgcgatc agtaatcagt
     3481 tgtacgaaga agccttcgcc atcttcaaga agttcgatgt gaacacatcg gccattcagg
     3541 tgctcatcga tcaagtgaac aacctggagc gggctaacga gttcgccgag cggtgcaatg
     3601 agccggccgt ttggtcgcag ctggccaagg cccaactgca gcagggtctg gtcaaggagg
     3661 ctatcgactc gtacatcaag gctgatgatc cgagcgccta cgtcgatgtc gtcgatgtgg
     3721 ccagcaaggt ggagtcttgg gatgacctcg ttcgctatct gcaaatggca cgcaagaagg
     3781 cgcgcgaatc ttacatcgag agcgaattga tctatgccta tgcgcgcact ggacgtctgg
     3841 ccgatctgga ggagttcatt tcgggtccca accatgccga tatccagaag attggcaacc
     3901 gttgcttcag cgacggcatg tacgatgcag cgaagctact gtacaacaat gtgagcaact
     3961 ttgcccgtct ggccatcact ttggtctacc tgaaggagtt ccaaggggcc gtggactcgg
     4021 cgcggaaagc caactcaacg cgcacatgga aggaggtgtg cttcgcctgc gtggacgccg
     4081 aggagtttag gctagctcag atgtgcggcc tgcacattgt ggtgcatgcc gatgagctag
     4141 aggatctgat taactactat caaaaccgtg gatacttcga tgaattgatt gcgctactcg
     4201 agtcggcttt ggggctggaa cgtgcgcaca tgggaatgtt caccgaatta gctatacttt
     4261 attcaaaatt caaaccttcc aaaatgcgcg aacacttgga gctgttctgg tctcgcgtta
     4321 acattccaaa agttctgcgt gccgctgaat cggctcactt gtggtcggag ctggtgttcc
     4381 tgtacgataa gtacgaggag tacgataacg ccgtcctggc catgatggct catcccacgg
     4441 aggcgtggcg cgaagggcac ttcaaggaca ttatcaccaa ggtagccaac attgagctgt
     4501 actacaaggc tatcgaattc tatttggact tcaagccgct cctgttgaac gacatgctgc
     4561 tcgtgctggc acccaggatg gatcacactc gtgctgttag ttacttctcc aaaaccggct
     4621 atttgccact cgtcaagcct tatctgcgtt cagtccaatc tctcaataac aaggcaatca
     4681 acgaagccct gaacggactc ttaatcgacg aggaggacta ccagggtctg cgcaattcga
     4741 tcgatggatt tgataacttt gacaacattg cgttggcaca gaaactcgaa aagcacgaac
     4801 ttaccgaatt ccgtaggatt gccgcctact tgtacaaggg aaataatcgc tggaaacaga
     4861 gcgttgagct ctgcaaaaag gataaactct acaaggatgc tatggagtac gccgccgaat
     4921 cttgcaagca agatattgcc gaagagttgt tgggttggtt cctagaacgt gacgcttacg
     4981 attgttttgc agcttgtctt tatcagtgtt acgacttgct gcgccctgat gttatcttgg
     5041 agttggcctg gaaacacaaa atcgttgact ttgccatgcc ctatttgatt caggttctgc
     5101 gcgaatacac aacaaaggtg gacaaactgg agttgaacga ggctcagcgc gagaaggagg
     5161 acgattccac tgagcacaaa aacattattc agatggagcc acaactgatg atcaccgctg
     5221 gcccagcaat gggcattcct ccacaatatg cacagaatta tccacctggt gcagcaacgg
     5281 taacggcagc aggaggacgc aacatgggct atccctactt gtaggacttg cgcccgataa
     5341 tgagatcatc aaaacaactt taaaaacaaa tgtatcagca ttaaaggaat accaataaaa
     5401 taagaaaaat aatctattaa ttgcatgtgc gccaaaaatt accaaaacga aacaacacag
     5461 taaacataac tttgaacatc attaaattaa agcaatgcaa ttaacaatcc aatttttggt
     5521 ttgtttgtag acagttaaaa attgattata tgttttgata attacagcac tctttattca
     5581 aatataacag aatatattac tttttatcat
//