From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse mammary tumor virus (GR) proviral 3' long terminal repeat.
Date: 28 Dec 92 21:30:13 GMT
Distribution: bionet
Checksum: 11939 4

LOCUS       MMTLTR2      1423 bp ss-RNA             VRL       01-DEC-1992
DEFINITION  Mouse mammary tumor virus (GR) proviral 3' long terminal repeat.
ACCESSION   J02272
KEYWORDS    integration site; long terminal repeat (LTR); proviral gene;
            unidentified reading frame.
SEGMENT     2 of 2
SOURCE      Mouse mammary tumor virus (MMTV) proviral DNA,from mouse (strain
            GR); clone GR40.
  ORGANISM  Mouse mammary tumor virus
            Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
            Retroviridae; Oncovirinae; Type B oncovirus group; Mammalian type B
            oncoviruses.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Kennedy,N., Knedlitschek,G., Groner,B., Hynes,N.E., Herrlich,P.,
            Michalides,R. and van Ooyen,A.J.
  TITLE     Long terminal repeats of endogenous mouse mammary tumour virus
            contain a long open reading frame which extends into adjacent
            sequences
  JOURNAL   Nature 295, 622-624 (1982)
  STANDARD  full automatic
COMMENT     Six bases at the end of each LTR form inverted repeats, and the
            first six bases of each flanking sequence form direct repeats. This
            endogenous long terminal repeat is not identical to that of the
            exogenous MMTV long terminal repeat.
               There is an open reading frame within both long terminal repeat
            regions. The open reading frame of the left LTR extends into the
            adjacent mouse sequence and the open reading frame of the right LTR
            starts at the viral env gene/LTR junction. The corresponding RNA
            for each hypothetical protein has not yet been isolated.
FEATURES             Location/Qualifiers
     LTR             68..1395
                     /note="3' LTR"
     repeat_region   68..73
                     /note="MMTV inverted repeat, 5' copy"
     repeat_region   1390..1395
                     /note="MMTV inverted repeat, 3' copy"
     repeat_region   1396..1401
                     /note="mouse direct repeat, 3' copy"
BASE COUNT      414 a    314 c    312 g    383 t
ORIGIN      About 7 kb after <mmtvltr1>; 80 bp upstream of PstI site.
        1 ccaaccacga tgcgtccggc gtagaccatc ttaacgtgct tcttttaaaa aagaaaaaag
       61 ggggaaatgc cgcgcctgca gcagaaatgg ttgaactccc gagagtgtcc tacacttagg
      121 agagaagcag ccaaggggtt gtttcccacc aaggacgacc cgtctgcgtg cacgcggatg
      181 agcccatcag acaaagacat actcattctc tgctgcaaac ttggcatagc tctgctttgc
      241 ctggggctat tgggggaagt tgcggttcgt gctcgcaggg ctctcaccct tgattctttt
      301 aataactctt ctgtgcaaga ttacaatcta aacaattcgg agaactcgac cttcctcctg
      361 gggcaaggac cacagccaac ttcctcttac aagccacacc gactttgtcc ttcagaaata
      421 gaaataagaa tgcttgctaa aaattatatt tttaccaata agaccaatcc aataggtcga
      481 ttattaatca tgatgttaag aaatgaatct ttgtctttta gcactatatt tactcaaatt
      541 caaaggttag aaatgggaat agaaaataga aagagacgct caacctcagt tgaagaacag
      601 gtgcaaggac taagggcctc aggcctagaa gtaaaaaggg gaaagaggag tacgcttgtc
      661 aaaataggag acaggtggtg gcaaccaggg acttataggg gaccttacat ctacagacca
      721 acagacgccc cgctaccata tacaggaaga tacgatttaa attttgatag gtgggtcaca
      781 gtcaacggct ataaagtgtt gtacagatcc ctcccctttc gtgaaagact cgccagagct
      841 agacctcctt ggtgtgtgtt aactcaggaa gaaaaagacg acataaaaca acaggtacat
      901 gattatattt atctaggaac tggaatgaac gtttggggaa agatttttca ttataccaag
      961 gagggggcag tggctagaca attagaacac atttctgcag atacttttgg catgagctat
     1021 aatggataac ctttatgagc ccaaccttgc ggttcccaag gtttaagtaa gttcagggtc
     1081 acaaactgtt cttaaaacaa ggatgtgaga caagtggttt cctgacttgg tttggtatca
     1141 aatgttttga tctaagctct gagtgttcta ttctcctatg ttcttttgga acttatccaa
     1201 gtcttatgta aatgcttatg taaaccatga tataaaagag tgctgatttt ttgagtaaac
     1261 ttgcaacagt cctaacattc acctctcgtg tgtttgtgtc tgttcgccat cccgtctccg
     1321 ctcgtcactt atccttcact ttccagaggg tccccccgca gaccccggtg accctcaggt
     1381 cagccgactg cggcattgta ccttaatgtc catctcttta tta
//