From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human complement protein (C2) gene exons 5-7, partial cds.
Date: 21 Jul 92 10:05:20 GMT
Distribution: bionet
Checksum: 49309     4

LOCUS       HUMC2A       1189 bp ds-DNA             PRI       21-JUL-1992
DEFINITION  Human complement protein (C2) gene exons 5-7, partial cds.
ACCESSION   M86920
KEYWORDS    complement protein.
SOURCE      Homo sapiens (library: cosmid) adult DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1189)
  AUTHORS   Johnson,C.A., Densen,P., Hurford,R.K., Colten,H.R. and Wetsel,R.A.
  TITLE     Type I human complement C2 deficiency: A 28-base pair gene deletion
            causes skipping of eoxn 6 during RNA splicing
  JOURNAL   J. Biol. Chem. 267, 9347-9353 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     mRNA            join(1..39,239..372,1170..1189)
                     /gene="C2"
                     /partial
     CDS             join(1..39,239..372,1170..1189)
                     /product="complement protein"
                     /gene="C2"
                     /codon_start=3
                     /translation="MLGATNPTQKTKESLGRKIQIQRSGHLNLYLLLDCSQSVSENDF
                     LIFKESASLMVDRIFSFEI"
                     /partial
     exon            1..39
                     /number=5
                     /gene="C2"
                     /partial
     intron          40..238
                     /number=5
                     /gene="C2"
     exon            239..372
                     /number=6
                     /gene="C2"
     intron          373..1169
                     /number=6
                     /note="partial intron"
                     /gene="C2"
     exon            1170..1189
                     /number=7
                     /gene="C2"
                     /partial
BASE COUNT      264 a    316 c    295 g    314 t
ORIGIN
        1 acatgcttgg ggccaccaat cccacccaga agacaaaggg tgagtgtttg aggtggggtt
       61 tctggttgag acgggtgctg gatctgggcc ggagaacggg aggatgcaac cttcctggag
      121 gccaggagcc ttggtggctc agccactgaa agggagggag gcagagaagc tggacctgct
      181 tggcgagagc gcaggaagga ggtggggatc tgaatcctcc ccttccacat ttctccagaa
      241 agcctgggcc gtaaaatcca aatccagcgc tctggtcatc tgaacctcta cctgctcctg
      301 gactgttcgc agagtgtgtc ggaaaatgac tttctcatct tcaaggagag cgcctccctc
      361 atggtggaca gggtcaggaa tcaggagtct gcctgcagca gaggccttcc tgtgctcact
      421 atctctctct gtctccttcc cctcctcaga accccactca cagcccacct cctccaagaa
      481 gtcttctcag attatactca tgccatgtag gaatcatgaa ttcaatttat acatcataat
      541 ttttattcca cagcactgtt gggacactgt gctgggctgg cgacacgaag atggaaaggc
      601 tgagtcttac tcagatcatc atctagacag tgtcagaagt agtagatacc acagatacga
      661 gaatctgtct gatatatcag tatattatat tatattctta aacttcaaca ttgtgcgagc
      721 ttaaatgtgt gtgatagact ggcatggtgc tagtgcctgt aatcccaaac atttgggagg
      781 ccgaggcagg tggatcactt gaggtcagga gtttgagacc agcctgacca acatgatgaa
      841 accctgtcct agctctggta gctggtatag tgctgcacat acagctaatt ttgtatttta
      901 gtagagatgg gttttgcatg ttggtcaggc tggtctcgaa ctcctgacct caggtgatcc
      961 acctgcctaa gtgttgggat tcaggcatga gccaccgcgc ccagccccta gcttcttcct
     1021 aacagccatt tcctagtgtc tcccctggtc cttgcctctg tcggtctcac tccagtttct
     1081 ctgcctcctc cagggccctt gtttgctctc ttaccatctc ccctttggct tcagggccct
     1141 ttacgctgcc tctcacttgc cccgcacaga tcttcagctt tgagatcaa
//