From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human liver-type 1-phosphofructokinase (PFKL) mRNA, complete cds.
Date: 29 Sep 92 10:07:07 GMT
Distribution: bionet
Checksum: 56546     7

LOCUS       HUMPFKLA     2914 bp ss-mRNA            PRI       29-SEP-1992
DEFINITION  Human liver-type 1-phosphofructokinase (PFKL) mRNA, complete cds.
ACCESSION   X15573
KEYWORDS    1-phosphofructokinase.
SOURCE      Homo sapiens (library: of Okayama and Berg) adult liver cDNA to
            mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Levanon,D., Danciger,E., Dafni,N., Bernstein,Y., Elson,A.,
            Moens,W., Brandeis,M. and Groner,Y.
  TITLE     The primary structure of human liver type phosphofructokinase and
            its comparison with other types of PFK
  JOURNAL   DNA 8, 733-743 (1989)
  STANDARD  full staff_review
REFERENCE   2  (sites)
  AUTHORS   Elson,A.
  JOURNAL   Unpublished (1990)
  STANDARD  full staff_review
COMMENT     Draft entry and computer-readable sequence [1] kindly submitted by
            A.Elson, 13-JUN-1989.
FEATURES             Location/Qualifiers
     CDS             56..2398
                     /EC_number="2.7.1.11"
                     /product="1-phosphofructokinase"
                     /gene="PFKL"
                     /codon_start=1
                     /translation="MAAVDLEKLRASGAGKAIGVLTSGGDRQGMNAAVRAVTRMGIYV
                     GAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARSKAFTTREGRRAAA
                     YNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTAWTYSHLNIAG
                     LVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALV
                     SALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISS
                     SYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPAC
                     VVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLTHQK
                     PPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEV
                     GWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLV
                     EARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRV
                     FIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLV
                     LRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKA
                     MLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQW
                     WLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF"
     polyA_signal    2872..2877
BASE COUNT      543 a    891 c    957 g    523 t
ORIGIN
        1 gcgacgcggc gcaggcggcg ggagtgcgag ctgggcccgt gtttcggccg ccgccatggc
       61 cgcggtggac ctggagaagc tgcgggcgtc gggcgcgggc aaggccatcg gcgtcctgac
      121 cagcggcggc gaccggcaag gcatgaacgc tgctgtccgg gctgtgacgc gcatgggcat
      181 ttatgtgggt gccaaagtct tcctcatcta cgagggctat gagggcctcg tggagggagg
      241 tgagaacatc aagcaggcca actggctgag cgtctccaac atcatccagc tgggcggcac
      301 tatcattggc agcgctcgct cgaaggcctt taccaccagg gaggggcgcc gggcagcggc
      361 ctacaacctg gtccagcacg gcatcaccaa cctgtgcgtc atcggcgggg atggcagcct
      421 cacaggtgcc aacatcttcc gcagcgagtg gggcagcctg ctggaggagc tggtggcgga
      481 aggtaagatc tcagagacta cagcctggac ctactcgcac ctgaacatcg cgggcctagt
      541 gggctccatc gataacgact tctgcggcac cgacatgacc atcggcacgg actcggccct
      601 ccaccgcatc atggaggtca tcgatgccat caccaccact gcccagagcc accagaggac
      661 cttcgtgctg gaagtgatgg gccggcactg cgggtacctg gcgctggtat ctgcactggc
      721 ctcaggggcc gactggctgt tcatccccga ggctccaccc gaggacggct gggagaactt
      781 catgtgtgag aggctgggtg agactcggag ccgtgggtcc cgactgaaca tcatcatcat
      841 cgctgagggt gccattgacc gcaacgggaa gcccatctcg tccagctacg tgaaggacct
      901 ggtggttcag aggctgggct tcgacacccg tgtaactgtg ctgggccacg tgcagcgggg
      961 agggacgccc tctgccttcg accggatcct gagcagcaag atgggcatgg aggcggtgat
     1021 ggcgctgctg gaagccacgc ctgacacgcc ggcctgcgtg gtcaccctct cggggaacca
     1081 gtcagtgcgg ctgcccctca tggagtgcgt gcagatgacc aaggaagtgc agaaagccat
     1141 ggatgacaag aggtttgacg aggccaccca gctccgtggt gggagcttcg agaacaactg
     1201 gaacatttac aagctcctca cccaccagaa gccccccaag gagaagtcta acttctccct
     1261 ggccatcctg aatgtggggg ccccggcggc tggcatgaat gcggccgtgc gctcggcggt
     1321 gcggaccggc atctcccatg gacacacagt atacgtggtg cacgatggct tcgaaggcct
     1381 agccaagggt caggtgcaag aagtaggctg gcacgacgtg gccggctggt tggggcgtgg
     1441 tggctccatg ctggggacca agaggaccct gcccaagggc cagctggagt ccattgtgga
     1501 gaacatccgc atctatggta ttcacgccct gctggtggtc ggtgggtttg aggcctatga
     1561 aggggtgctg cagctggtgg aggctcgcgg gcgctacgag gagctctgca tcgtcatgtg
     1621 tgtcatccca gccaccatca gcaacaacgt ccctggcacc gacttcagcc tgggctccga
     1681 cactgctgta aatgccgcca tggagagctg tgaccgcatc aaacagtctg cctcggggac
     1741 caagcgccgt gtgttcatcg tggagaccat ggggggttac tgtggctacc tggccaccgt
     1801 gactggcatt gctgtggggg ccgacgccgc ctacgtcttc gaggaccctt tcaacatcca
     1861 cgacttaaag gtcaacgtgg agcacatgac ggagaagatg aagacagaca ttcagagggg
     1921 cctggtgctg cggaacgaga agtgccatga ctactacacc acggagttcc tgtacaacct
     1981 gtactcatca gagggcaagg gcgtcttcga ctgcaggacc aatgtcctgg gccacctgca
     2041 gcagggtggc gctccaaccc cctttgaccg gaactatggg accaagctgg gggtgaaggc
     2101 catgctgtgg ttgtcggaga agctgcgcga ggtttaccgc aagggacggg tgttcgccaa
     2161 tgccccagac tcggcctgcg tgatcggcct gaagaagaag gcggtggcct tcagccccgt
     2221 cactgagctc aagaaagaca ctgatttcga gcaccgcatg ccacgggagc agtggtggct
     2281 gagcctgcgg ctcatgctga agatgctggc acaataccgc atcagtatgg ccgcctacgt
     2341 gtcaggggag ctggagcacg tgacccgccg caccctgagc atggacaagg gcttctgagg
     2401 ccagccatgc ccgagctgcc cctccccagc ccccacccat gccagcgcac gcgccagggc
     2461 tcagatgggg cctgggctgt tgtgtctgga gcctgcaggc aggtgggggc tgcgtccctg
     2521 ctcagcccat cccctgcctc tactccctgg ccacctgcca ggcctccctc cggctggtgt
     2581 cttgagacca gcctgccagg cctccagcag gaggacagag tgccctgggg catccacctt
     2641 cctgcccagg ggacgtggcg ctgtcggtgt ttggaggctg ctgccccctg gctttggcgc
     2701 cccatgggcc ctcagcgtct ccccatgctg ggctcactac atgggccagc ccttgctcta
     2761 cctggccggt aggctgctgg cgcctaggtt gtgttgagag ggggatgccc ctggccctgc
     2821 ctcactgtga cctgctcctg cccacgtgca gcacctgtca ccttttctag aaataaaatc
     2881 accctgactg tggggtgcca tcggtctccg gaga
//