From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens phospholipase C-beta-2 mRNA, complete cds.
Date: 1 Sep 92 10:02:47 GMT
Distribution: bionet
Checksum: 20526     9

LOCUS       HUMPLCB2A    4519 bp ss-mRNA            PRI       01-SEP-1992
DEFINITION  Homo sapiens phospholipase C-beta-2 mRNA, complete cds.
ACCESSION   M95678
KEYWORDS    phospholipase C-beta-2.
SOURCE      Homo sapiens cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4519)
  AUTHORS   Park,D., Jhon,D.-Y., Kriz,R., Knopf,J. and Rhee,S.G.
  TITLE     Cloning, sequencing, expression, and G-q-independent activation of
            phospholipase C-beta2
  JOURNAL   J. Biol. Chem. 267, 16048-16055 (1992)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     CDS             165..3710
                     /product="phospholipase C-beta-2"
                     /evidence=EXPERIMENTAL
                     /codon_start=1
                     /translation="MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKG
                     YYLYWTYQSKEMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVV
                     SGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLN
                     SEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPR
                     PEIDEIFTSYHAKAKPYMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEP
                     SGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAG
                     QFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIA
                     ESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPS
                     PEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAVWAGEEGTELEEEEVEE
                     EEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRS
                     YVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMV
                     ALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSI
                     TVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKIL
                     MPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMK
                     DYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALA
                     PTSNGSPAARAGAREEAMKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGAR
                     RWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGPEGV
                     DGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKE
                     TSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTE
                     NLERHQEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLRTCF
                     PSEAKDKPERACECPPELCEQDPLIAKADAQESRL"
BASE COUNT     1033 a   1314 c   1301 g    871 t
ORIGIN
        1 cagccagggc caccccaggg gctataagag caactagatt tctggagcag ctcggggatg
       61 ggtgccattt gagcccagct tggctccccc tcctggctgg cctccttcct gcccttctgc
      121 ctgcctgtgt ctgctgagat tctgcaaaga ggaacgttgg caccatgtct ctgctcaacc
      181 ctgtcctgct gccccccaag gtgaaggcct atctgagcca aggggagcgc ttcatcaaat
      241 gggatgatga aactacagtt gcctctccag ttatcctccg tgtggatcct aagggctact
      301 acttatactg gacgtatcaa agtaaggaga tggagtttct ggatatcacc agcatccggg
      361 atactcgctt tgggaagttt gccaagatgc ccaagagcca gaagctccgg gacgtcttca
      421 acatggactt tcctgataac agtttcctgc tgaagacact cacggtggtg tccggcccgg
      481 acatggtgga cctcaccttc cacaacttcg tctcctacaa ggagaacgtg ggcaaggcct
      541 gggctgagga cgtactggcc ctagtcaaac atccgctgac ggccaacgcc tcccgcagca
      601 ccttcctgga caagatcctt gtgaagctca agatgcagct caactctgaa gggaagattc
      661 cggtgaagaa ctttttccag atgtttcctg ctgaccgcaa gcgggtggaa gctgctctca
      721 gtgcctgcca cctccccaaa ggcaaaaatg acgccatcaa tcctgaggac ttcccagaac
      781 ctgtctacaa gagtttcctc atgagcctct gtcctcggcc agaaatagat gagatcttca
      841 cttcttacca tgctaaggcc aaaccctaca tgacgaagga gcacctgacc aaattcatca
      901 accagaaaca gcgggactcc cggcttaact ccctgctgtt cccgccagca cggcctgacc
      961 aggtgcaggg cctcatcgac aagtatgagc ccagtggcat caatgcacag aggggccagc
     1021 tgtcacctga aggcatggtc tggtttctct gtgggccaga gaacagcgtg ctggcccagg
     1081 acaagctgct gctccaccac gacatgacgc agccactcaa tcattacttc atcaactcgt
     1141 cccacaacac ctacctgaca gccggccagt tctcaggcct ctcctcggct gagatgtacc
     1201 gccaggtgct gctctctggc tgccgttgcg tggagctaga ctgctggaag gggaaacccc
     1261 ctgacgagga gcccattatc acccatggct tcaccatgac cacagacatc ttcttcaaag
     1321 aagcaattga ggctattgca gaaagtgcct ttaagacctc cccctatccc atcatcctgt
     1381 cgtttgagaa ccatgtggac tcaccccgcc agcaggctaa gatggctgag tattgccgga
     1441 cgatctttgg ggatatgctg ctcacagagc ccctggaaaa gttcccacta aaaccaggtg
     1501 tccccctgcc cagccctgag gatctcaggg gcaagatcct catcaagaac aagaagaacc
     1561 agttttctgg ccccacctcc tccagtaagg ataccggtgg ggaggctgag ggcagcagcc
     1621 cacccagtgc ccctgcagtg tgggctggcg aggaagggac tgagctggag gaggaggagg
     1681 tggaagagga agaggaggag gagtcaggaa acctggatga agaagagatt aagaagatgc
     1741 agtcggatga gggcacagcg ggcctggaag tgacggctta tgaggagatg tccagcctag
     1801 tcaattacat ccagcccacc aagttcgtct cctttgagtt ctctgcccaa aagaaccgaa
     1861 gttatgtcat ctcgtccttc acagagctca aggcatatga cctgctctcc aaggcctcgg
     1921 tgcagtttgt ggactacaac aagcgccaga tgagccgcat ttaccccaag ggaacccgca
     1981 tggactcctc caactacatg ccccagatgt tctggaatgc tggatgccag atggttgccc
     2041 tcaacttcca gacgatggac ttgcccatgc agcagaacat ggcagtattt gagttcaacg
     2101 ggcagagcgg ctacctcctc aagcatgagt tcatgcgccg gccggacaag cagttcaacc
     2161 ccttctcagt ggaccgcatc gacgtggtgg tggccaccac cctttccatt acggtgatct
     2221 ctgggcagtt cctgtcagaa cgcagcgtgc gcacctatgt agaagtggag ctgtttggcc
     2281 ttcctgggga ccccaagagg cgctatcgaa ctaagctgtc acccagtact aactccatca
     2341 atcctgtctg gaaggaggag ccctttgtct ttgagaagat cttgatgcct gagctggcct
     2401 ccctcagagt ggctgtgatg gaggaaggca acaagtttct tggacaccgc atcatcccca
     2461 tcaatgccct aaattctggg taccaccacc tgtgcctgca cagtgagagc aacatgcccc
     2521 tcaccatgcc tgcgctcttc atcttcctgg agatgaagga ctacatacct ggtgcttggg
     2581 cagatctcac tgtggccctc gccaacccca ttaagttctt cagtgcccat gacacgaagt
     2641 ctgtgaagct caaggaggcc atgggaggtc tgcctgagaa gcccttccca ctggcgagtc
     2701 cagttgccag ccaggtcaat ggggcgttgg ccccaacgag caatgggtca ccagcagcca
     2761 gggccggggc cagggaagag gctatgaaag aagctgcgga gccgcggacc gccagcctgg
     2821 aggagctccg ggagctaaag ggcgtggtga agctgcagcg gcggcacgag aaggagctgc
     2881 gagagttgga gcggcgcgga gcgcggcgct gggaggagct gctgcagcgg ggcgcggcgc
     2941 agctggcgga gctcgggcca ccgggcgtgg ggggcgtcgg ggcctgcaag ctcggtcccg
     3001 gcaagggctc tcgcaagaag aggagcctgc cccgcgagga gagcgccgga gccgcgccgg
     3061 gcgagggccc tgagggcgtg gacgggcgcg tgcgggagct gaaagacagg ctggagctgg
     3121 agctgctgcg gcagggcgag gagcagtacg agtgcgttct gaagcgcaag gagcagcacg
     3181 tggccgagca aatctccaaa atgatggagc tggccagaga gaaacaggcg gcagagctga
     3241 aggccctgaa ggagacgtcg gagaacgaca ccaaagagat gaagaaaaag ctggagacaa
     3301 agagactgga gcggatccag ggcatgacca aagtcaccac agacaagatg gcccaggaga
     3361 ggttgaagag agagattaac aactcccaca tccaggaagt agtgcaggtg atcaagcaga
     3421 tgacggagaa cttggagagg caccaggaga agctggagga gaagcaggcg gcttgcctgg
     3481 aacagatacg ggagatggaa aagcagttcc agaaggaggc gctggcagag tacgaggcca
     3541 ggatgaaggg tctggaggca gaggtgaagg agtcggtgag ggcctgcctc aggacctgct
     3601 ttccctccga ggccaaggac aagcctgaga gggcctgcga gtgcccccca gagctgtgtg
     3661 agcaggaccc actcatagca aaggcagatg cccaggagag ccgcctctga tgcccccatc
     3721 ccactgggac atttagcaag gaggttcagc cccttctctg ggatgtggtt ctattccccc
     3781 aggaaaaagg agccccagcc ttctgaggct gtgggaacct gtggctgcct tggacgctgc
     3841 agccccctcc tcaacggcca ggccagagtc tgagacagga cccaggcacc ctcacggcag
     3901 ggcctctctg gggcctagaa gtcttctcaa gctgacttcc tacctccccc tccatctcta
     3961 gataagtgtc atatatttgt tgagggcaaa agactatgga ctggaaggca gaaagtggga
     4021 tcctggcccc actctgcctt tcctattgag caaccagctc tgggctcagt ttcctcacct
     4081 ggagggttgg acccactcac ctccactcta gccccgaacc ctcctgcccc aggcttccag
     4141 gccccatcag gcctgccctg agttggcctt gtccactcct tgaggcagat cctggcacta
     4201 cctcacagct ccctggggac ggccactccc tggctgaggg ccctcccctc ccctctgcct
     4261 gtccggaacg ggaggctgaa atggaaaagc tgccttggcc ctgcttggct gagtcacaag
     4321 gggcagtggg ctcttgggtg ctgttccacc ctgaccctgg ctcacccctc ttcctaggcc
     4381 tgggggcagg cagttcctac catgtacccc tctcaggctg cctgcctgac aaggtcagca
     4441 tcatttgctc tcctgaattt atgaggttta tttatttttc tctttcctac tcctattaaa
     4501 gaacctcgtc ccagtgaaa
//