From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human profilaggrin gene exons 1-3, 5' end.
Date: 13 Jan 93 05:48:18 GMT
Distribution: bionet
Checksum: 17572 25

LOCUS       HUMPROFILX  17630 bp ds-DNA             PRI       12-JAN-1993
DEFINITION  Human profilaggrin gene exons 1-3, 5' end.
ACCESSION   M96943
KEYWORDS    calcium-binding protein; profilaggrin.
SOURCE      Homo sapiens (library: EMBL3, Clonetics) epidermal DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 17630)
  AUTHORS   Markova,N.G., Marekov,L.N., Chipev,C.C., Gan,S.-Q., Idler,W.W. and
            Steinert,P.M.
  TITLE     Profilaggrin is a major epidermal calcium-binding protein
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            join(3618..3671,13386..13544,14115..>17630)
     TATA_signal     3591..3597
     exon            3618..3671
                     /number=1
     intron          3672..13385
     exon            13386..13544
                     /number=2
     intron          13545..14114
                     /number=2
     exon            14115..>17630
                     /number=3
     CDS             join(13407..13544,14115..>17630)
                     /product="profilaggrin"
                     /codon_start=1
                     /translation="MSTLLVFIFAIINLFNEYSKKDKNTDTLSKKELKELLEKEFRQI
                     LKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMVFKLAQAYYESTRKENLPISGHKHR
                     KHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKE
                     RKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYE
                     NTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRH
                     ENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSR
                     HPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSAGERHGSHHQQSA
                     DSSRHSGIGHGQASTAVSDSGHRGYRGSQASDNEGHSEDSDSQSVAGQRQARSRHQSH
                     QESTRGRSRGGSGRSGSFLYQVSTHEQSESSHGWARTSTGRRQGSRHDQAQDSSRHST
                     SQQGQDTIHAHPGSRRGGRHGYHHEQSADSTGHSGSQHSHTTTQGRSDASRGSSGSRS
                     TSRETRDQEQSGDGSRHSGSHHQEASTRAESSRHSQVGQGESSGSRTSRNQGSSFSQD
                     RDSQAQSEDSERRSASGSRNHRGSAQEQSRDGSRHPGSHQEDRAGHRQSAESSSQSGT
                     HHAENSSGGQAASSQEQARSSAGERHGSGHQQSADSSRHSGIGHGQASSAVRDSGHRG
                     YSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQESTRGQSRGRSGRSGSFLYQVST
                     HEQSESAHGRSAPSTRRRQGSHHDQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHY
                     EQSVDRSGHSGSHHSHTTSQGRSDASHGTSGSRSASRQTRDEEQSGDGTRHSGSHHQE
                     ASTQADSSRHSQVGQGQSAGSRTSRNQGSSVSQDRDSEGQSEDSERHSGSASRNHRGS
                     AQEQSRDGSRHPGSHDEDRAGHRQSADSSSQSGTRHTQTSSRRQAASSQEQARSRAGD
                     RHGSGHQQSADSSRHSAIGRGQASSAVRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQ
                     RQAGSHQQSHQESTRGRSQGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHE
                     QARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSD
                     ASHGQSGSVDLQVD"
BASE COUNT     5711 a   3271 c   3343 g   5305 t
ORIGIN      
        1 gcatgcaagt gggatcagcc agactggcag gaagtggggc atgaaaaccc aagaactatc
       61 ctcctgtttg cagtataatg ttacccctgc agttattaaa ctgcacagat caaataacta
      121 tctgaactga gctgagctga gtcaagcaaa gaaatgtact tcaatcatag aatagtagct
      181 gtcaggttga aaagggcatc tatcagacat ctacccaatg ttcctctacc taactcccat
      241 cctaattatc cctgtctcat gttcatctcc ctgtaattga tgcaacctga tgcaacataa
      301 agaggatttg gagtgaaaag ccctgagttg gaggcctggg cttgactttt taatttacta
      361 gcccatacca cattggtcct tctagtcttc agctacaatg tgagcagatt acatagttga
      421 tgccaagatt ccatcagttc aaattctcta ggcaataata ggggaactca ctatctccaa
      481 aatattattt cgatgtttgg acaatttcta ttaaaaagtc gtcacttaca taaagccaaa
      541 acatggtttc ttatagtttc tacatattta tctgagttct acctgccttg agattatata
      601 gtccaagtat aatccctctt ctatataaca gccactcata tagccaaaga cagatattgc
      661 atctcccatc catctatcca tccatccatc catccatcca tcccactgag ttctgtttgc
      721 cactcatcta gacaatcatt ctatctactt tactcagaac acataccaat ttgtccatat
      781 ccttactgaa aaatggtcat cagaactgaa caaagagcta cagaaatagt ttgataaatg
      841 ctgagccaag tacctcacca cctattttgt tccagctaat gtgtttattt taatgcagcc
      901 taatatcaca ttatcttttt ggctatggac tcactctgcc actgccacaa tattgctttt
      961 tttactcatg tcttctaccc tatccttgta aagtgtaatt tggaactgga gacagaattt
     1021 tactttttca taatatcatt atcagatttg agccatggtg caacatgata aaatcttctt
     1081 gaatcctcag tctatcctaa aaatatttgc catctatcca aattttcacc taagttattg
     1141 ataaaataca atgagcacaa catggtcagg aaaaaagtcc tagagcagac cactaaacaa
     1201 taccctccat attgacataa ttctgcaaga tttggggtct tttggcccca aagaaggtca
     1261 tatccaagat tgcctcactt cttgacactc tctcaatgct accttcttca ctcactcata
     1321 gtccatggtc tagtctttct gctgatcctg caatgatttc cacagttaag ttcacccaga
     1381 cataggtact ttgagagaaa tcactgttta aaacattaaa aatataaata aggttaacaa
     1441 aaaaaggata aaagttcaca cccagaacaa tatgccatgg tggaaataat gtgggagttg
     1501 gagtctgaat aacctcagat taaatcctag ttctgtaact tacttgcttg gtgaccttgg
     1561 gtgccttatc agtatcagtt ccctcatctc taaaatagag gaataataat gacctcaaag
     1621 ggttgtcctg atgattaaaa ttaatacacg caaaatctta gcacattcct agcacataat
     1681 gggtatacaa tatagattac tatcattatt acatcatggt agagacaaaa tcgaataact
     1741 actggcataa aaattagacc caagaagaaa aaaggagaaa atgaatatct gtgttctcca
     1801 gatgttaacc aatactccac aaaagaaaga atcaatggtc taataaggtt aagaacgaga
     1861 cattaaacac agaaaatttt tgagcccgta taaaaataga gaaactgaga gaacaagatt
     1921 ggcacaccct tgcatccctt atttgatcat gtcccaggca ttgctgtagg gcccaaggac
     1981 acaaaggatg tactcagacc cagtcaatgc tagggtgaga agaaacacag gattcaaggc
     2041 accagggggc agggggtaca catataaata agtaattaat ataaaatatc accagtgcta
     2101 ttgagaggta aatacagagt atgtgaggga acactgaata aatctggaga tgtcaggtaa
     2161 ggctttatgc aggaggtggt aattttgaag aatcataaaa gataaagaga agttaaggat
     2221 gagggtctct caagtcaagg tagtggagga tagcacgcaa agattttgaa cagtagtgga
     2281 ccaatatggg ctcgtccaag aaatattgct cattctagag tgacttttcc atgagataca
     2341 ggtaataaga gggacaattg aaaagataca gattcatgcc tattgtaaag gggcttgtac
     2401 gtcaggtaaa aaagtctgaa attctacagg caagaagaaa ccagcacagc gaatgacata
     2461 agatggtaag ccagcttaat agtagagaga gaggctatgt tacgacactt ttttttcttt
     2521 accaataccc aattgaaaga tggtcaggtc cagaactaaa aattatagca ctggaggtag
     2581 agaataggcc tacataaaca aaatctaagc ctgagtataa ttgatacgat gtgacatgag
     2641 catgaggggt taaggaaaag gagaatgaaa tgacttgtct agcttgagac acccagtgtg
     2701 tgggggcatc attaccaata tatgggcttc tggaggatag atcattttgg taggaggcac
     2761 aatgtaagtt cagttttcaa cactatggat tgagataacc atgggacatc catatggaga
     2821 tgcaatctgc tcaacataac agtgtgtata tcataagaca gaccagggat aggagtcccc
     2881 tgtatattta tggcaataaa agaaaattca tggtttaaga aggaagagta tgtggaacat
     2941 gtctctgatg ccacgatgta ataaccttga aaacaaagta aaattacact aatgagtctt
     3001 gcctaattaa actcatgctc ctagtgatca ccacttctag ttcaattgtt cacattcttg
     3061 ctctgctttg aaaaattaaa attaaatttg cctatcctct actgaccata atttctagaa
     3121 gacggcattc atctcatggc aagttcttca gtacccaaag atggaataca tagattaaaa
     3181 aagaacatat atgtagatgc ttgtgatgtt ttcctatcat aaattgaatt tcaagttctt
     3241 ataaacgtat taatatgtcc tactcttcta gagacaagga tcaagaagtg tatttatcaa
     3301 tagatattta ccaagcacct gtcaagccaa agtggggtta cagaaaagta ggtatgggcc
     3361 ctgcacacaa acaacctgta ttagccaaag ggacccttcc ataaaatttc caatatgtaa
     3421 acccaaattt ggaacttgct gaaacaagta cagatgagta cgtgaggaag ctgggaagta
     3481 aacacaggtt cgtggagaaa tagaggtgga gatatgggtg gatctaggtt tggttaggaa
     3541 tgaatcagac catcccacag agggtggctc ctccctgcat tggggcctgc tataaaaggg
     3601 ccattatctc agccttcagt acccagcagg ctccttcagg ctacattcta tttgctcatt
     3661 tggtgaacaa ggtaagaagg aatacattta attttgtcta cttactatta accaaggtgg
     3721 aaatctgaat gtatgtgtac tgtaaggcaa aaggttctgg aagtttaggg tttttctctt
     3781 tctttttagt ggcactaaaa ggtttatttc tatatagaag gaaaatgagg gcataaattt
     3841 gctttccatg gagctactca atactctgta ttgttagatt gtccatttat tcatttactt
     3901 aacaaatatg tattaactac cttctacttg gtcttggctc tatctatgca gcagtgaagt
     3961 atataaactc ctagcagctt acctttaata gggggaaaac atttagtaaa caacaataaa
     4021 caataagata attttaaata gtgataagaa caatgaagaa aataaaagag tgatgtagta
     4081 gagctggggg tgtccgtctt ttggcttccc tgggtcataa tggaaaaaga attgtcttgg
     4141 gccacacata aaacacactg acactaataa tagctgataa gcttaaaaaa aaactcgtaa
     4201 tgttttaaga aagtttacaa atttgtgttg ggccacattc aaagctgtcc tgggccacag
     4261 attggacaag caagcttgta gtaaagtgat gggagggagg aggaaagtgc tttaaattag
     4321 atggccaggg gaagacctct ctagggaatt atctttgagt tgagatctta aacacaaaag
     4381 aaactagcca aggcaaaggg caagattcta agcaagagta aaccttgtcc caaagagcaa
     4441 aaagaagcta gtgtgcctta agagcataca tagttaaaaa gaggaccagt ggtatatggt
     4501 gatgtcagag agctagacag cgtagctcat gtaaagaggg gcacagtatg aattaaaaca
     4561 gtacatgtta gattttagca tgtacttaaa ggggtattaa gcaggaggag taagataatc
     4621 tatgttttta aaagaccact ctggggctgc tacgtggaaa acgggaatat aggaaggcaa
     4681 gaggaggagc agggagagac tgcattcttt tatgtgaaag atgatggaaa taatagaaat
     4741 aacgagaaat aactgtttgc tcatacaaaa atctagaagt tatccatgat tcctgttttc
     4801 tcatcacact gattcatcac cacgtccagt caactctgcc tacaaacctg ccaaatctat
     4861 ccatttatcc cccctctctg ccattatcat cctagtccag tctaccttca tctcccaaca
     4921 ctgactatta tgttatctga aaatataaca atttattcat ccatttgtct atgggtagat
     4981 acttgggtct cttccatttt ggggggtatt ataaataata gggctatgca cttttttgtg
     5041 tactactttt ggttacacat atgtacatat ttcagttggg aatatttcct aagagtaaat
     5101 cgctaggact tagatactgt caacatttca agtgctctgt cacttatgtg tcctagccag
     5161 ccttacataa aaaaaaaaaa aaaaatctca attctccaca ttctcaccaa tatttggtat
     5221 tgtcaaggat ttttttcttt cttatctttt tagtcacttt ggtgggtgta ttgaggtctc
     5281 acacgttatt tcaatttgca tttccctagt gcataacaag gttgagaagt tttgatatgt
     5341 ttattggcca tttggatatc cttttctgta acgttcctaa ggtattcatt tttccattga
     5401 gttaactgta ttttttattg atttatagaa gctattttta tattcaggac agattccttt
     5461 attggttaaa tgtgtttgta tatctcccac tgtgtgcttg tacatctctc ttctaatgct
     5521 atctttaaaa gaataaacat tcctactttt aatgcagtac aatttatcag tcttttttct
     5581 tattaattag tactttttga attttattta agtatttccc caccccgagg tcctgaagat
     5641 attctccaat gttatcttcg tttatctctt acatgtaaaa tcaacctgga aactattttt
     5701 ttttccattt gaaaattcaa ttaacccagc accatttatt caagactatt ctttctctac
     5761 tgacctacac taccatcttt gccattaacc aaatgtccag agtgatataa gactgacttt
     5821 atactattat cttttatcat tccatttgtt tagccttgca tcatgccata ttttcttcct
     5881 ttataacaca ccttgctatc tggtatgtct tccaacttag tcttcttaaa gatggtctta
     5941 cctaatctta gccctctaca ttttcatata aattttagaa atcaccttat taatctttat
     6001 tttttaaaaa aacttcagat attcagaatg gatttcattg catctataaa tgaatttaag
     6061 gagatttgat atcttaatgc tatttagact ttcagttcat aaacaagcta tatattgtcc
     6121 atttatttaa atctttatct caatatttat aattttctga gtatagctct ttcatgtttt
     6181 cttagattta ttcctaaaaa tttcctcttt ttttatgctt ttatgaatag cctcctttcc
     6241 tatttcattt tctcagcact tataatctca acttttataa tattctgagt acagccattt
     6301 catatcttta attagattta ttcctaaaat ttttctgatt tttttatgct tttgtaaata
     6361 gcatcttttc ttatttcatt ttctaagtgt ttattcgtgt tatatagaaa tacaattgat
     6421 ttttgtatac ttataaccag aagcatgttt agtttattta ttctaatagt ttagctatac
     6481 attcttttgg attttccaca tacaaaagtt atatcattct gtgagtaata acagttttat
     6541 tacttctttt ccgaattact ctgcttttaa ttccttttcc taacgtattg ctctagctag
     6601 gacttttagt acaatgttaa ataggatgat actatacata gtatatatca ataggatgat
     6661 gcaggcatac tagtttcatt cccaaacttg gagatgaaag ctttcatttc accattaaat
     6721 ataatttttg ctatgacatt tttcaaagac ataatctttt atttattaat cagaattaat
     6781 attggatttt atcaattttt catctattga gaggttcata taattttccc cattattcta
     6841 tttcagtact taattggttg gttttcaaat gttaatccaa aaatgaattt tggaataaaa
     6901 tgtagttagg aataacatta tattcttttt atatactact gaattcagtc tgctattact
     6961 aattctttca gagtttgcat ctatattgaa aggaattgat cctgaaaatt ttgattctta
     7021 tatcgttgtc aggttatggt actgaggcca gttggattaa taaaatgggt gtttcctgtt
     7081 tttcatttct ctgaaataat ctatgtgatg ttatagttat ttctttcttt cactttgaat
     7141 agaattcagt aaagccatct gacctgcagt ttctccccca ctggaaatga atgcatttaa
     7201 gattcaattt ctttaataaa catagtacta tttaggtttt ctatttattg ttggttcagt
     7261 tttggtaaca agtgtttttc tagacatttc ttctatgtca tctaaatttt caaattagct
     7321 ggtataatgt ttttttataa tatgctcttg tcatctttct aatgtctaaa acctcgatag
     7381 caatgtcccc ttttactttc ctgatattgg tacttactct tctttccttg attaacttgc
     7441 aggggttatc agttttatta gatttttcaa aggctgaatc ttggcactgt tggttctcta
     7501 aattttcttt ctcttttatt aattttagtt atctttatta tttccttcgt tatactttct
     7561 tagggcttaa tttgttcttt ttaaaacttc ttgaaatata tgcttaggta attaattttt
     7621 cagtctttca tatacatata tatacacaca caactgtatg ctgcttataa gattcacaca
     7681 taaaaaatga taacagtgat tgaaaatgaa aggatgggaa aaagagatat cattcatata
     7741 tatatgtatg tgctttatat acatatatat gtgagtgtat atatgtatat atgtgtgtgt
     7801 gtatatatat ataggctata aatatctatt aggcatggaa ttaatgtatt ccacaaagtt
     7861 atgctatttc atatttttct cattttcatt tagttcaaaa tattttctaa ttttgcattg
     7921 taatttattc aatgacccat tgattattta gaagtcatta attttcaaac acttaaagat
     7981 ttttctagtt atcttcctat tatttaatgc ttgcttcatt ccactgtgtt agagaacaaa
     8041 ctctatcatt tcaacccttt aaaatttatt gaaacttgct ttatggccca gatataggtc
     8101 aatttcaaaa gaatggatat tgtgcagttg ttaggtgtag tgttcaatgt atgttgatgt
     8161 tttattaata attttgtaga aatatttcta cattcttaca tattttttta gtcttcttct
     8221 atcagttgct tgagagaagt gtatttaaat accccactat gattgtagat tgcctggtcc
     8281 tccttatact tctgtcgatt tttatttatg tattttgagg cttcctggag aattgatctt
     8341 ttattattat aaaatttcct tctagcaata ttttttgcct taaagtctgc tgacagatat
     8401 gaatataata ataacagctt tcttttagtg tttgaatggt atctctttct tccacccttt
     8461 catttacaat cattttaatc acattttatg tgtgtctctt ataagcagaa tacagttggt
     8521 tttttttaat ccagtctgac agccttgtcc cttaattagc atatttactc tatttatatt
     8581 cagagttatt atggaactat ttggtttaca tctctacaat attactactt ggtttctact
     8641 atctcacctg ttctgtattt ctttttctat tcttgacttt tttggattaa gttaatattt
     8701 accagttaat tatctttata caaaagctta ttaattatac actcttttat tattatctgc
     8761 atccttgccc taaaagcatg catccttgat ttgttagggt atattattaa gaaaaaaata
     8821 ctttaacccc tacccaaata atacaagtat cctacaatac ttaactccat tttctcactg
     8881 ccttatctgg gattgttatg tattttaatt ctatttatct taaatcctga aagattacta
     8941 ttattatttt atcgaatcaa tatctagcta tatttttcca cacatatgct ctttccattg
     9001 ttcttattct ttcttgctcc tctgtgcttc caactagaat tatcctttaa tatttccttt
     9061 acagtaggtc tctggtgatt agctctgttt ttctttgctt gaaaatatct ttacatgttt
     9121 tctttttggt ggatattttc actgttaaca tataacttat tttgcttcag aaagatgaat
     9181 ataacatttc atcgtctttt agcttccatt gtttcttttg ttttgacaag tatcaatctt
     9241 attgtcgtcc tttgaaggta atacaagtgt ttctctgtct gctcttagga tttcctcatt
     9301 gcctcttttg ttcagcagtt ttattattat atgtcttgct ttggttttct tttatatctc
     9361 ctgcttggag tttataatat cgttttgaac ctgtaccttg atatctttca tcagttttag
     9421 aaaattttgt cttttaattc cccaaatact atatttccct ctaaatctga atgtaagccc
     9481 caataaattg tcacaatctt gatagctctg tgataccttc aaaacacaca cacacacaca
     9541 cacacacaca cacacatttt ctagttgtat tcagagttag tctgaaacta ataaacaatt
     9601 gcacaaagca atctttaaaa atcaaaccat attagatcac tctcttacca aaaaatatca
     9661 tctagtctca tcacacctaa aataaaatgc acaaatgtca ccttatttag aaagatcatt
     9721 atctgacccg tctgtatctc tgactttatg ttgtattact cctgctttgt ccacaatttt
     9781 ctaactgagt tggtcttttt ctatatctct aacatgacaa gctgattttc atcttggaat
     9841 cttcgcattg ttccttgtgc taaaattctc taattaacaa ggctacttcc ttcttatttt
     9901 tccattttaa gttcaaatgt cccctctacc acaaaacctc ctttccttaa agtaccccca
     9961 aatattctgt ataatagcac tcttatttta gttatgtaca tatcacttat caatatctaa
    10021 ttgttgaatt aatttatgtt tgtttattgt cttcacaaaa gtaggcaggc acctcatcta
    10081 tcttgttcac tactatatct ccaaagcatg aaacagtgcc taacccttta gtagctgttc
    10141 aatacttgtt aaataaatga aggaatgaat gaatgaatgt aagctctgag aaaaggttat
    10201 gcctagaggt atcaattttg aagtcatcag atagatggta tctgaagtga tgggatccaa
    10261 tgacattgcc tcagaaagga gtgtagattt ttttaaaaag aaggtctaag acacagccac
    10321 agatatttcc aaccttttga gattgagtag aagagaggtt agtaaagaat actgagagac
    10381 aacagcattc aatgggtaag aggaatatca gaagaatatg gtgtcatgag atccaagaaa
    10441 aaaagactcc attaagaaag gaatggttaa ttctatttca cataccaaga gattagtaag
    10501 atgatgatga tgaggtaatg atggagaaat gacactgtat tcaacaactt ggagatcaca
    10561 gatgatttga cacaaagcag tttcagtaga gtttggtgat agaaaattga gagaagcagg
    10621 ttaaaaagat ttgtgggtgg taaacatttt aagagagaaa gcagagaaaa cttctccaag
    10681 actccagaga aatgaagcag ttaattaggc tagtaagatg ttaggagaaa tgttggggga
    10741 gggtggaata atggttcgag ggaagggttt taagatggaa gatactccag catgtttctg
    10801 tggtgataaa aataaactac tagagaagga aacagagtgt aagtagggaa aactgactaa
    10861 ttttagggat attttgaaag taggatcaat aaaacatgtt gatggaatag atattggatg
    10921 taagaaaagg agaatcaact aattttcagg tttacgactt gagccatcag gaagacagga
    10981 ataactgatg aggataacgg gtgtgcgaca tttttagggt aaagcagttg aaaatcaaga
    11041 cttctgtttt gaacataata gatttaagat ctctacaaga ctcaagtaga aatactggat
    11101 aggcatttag acatacacat ctcaagttta ggggacagtc agtgactggg ggtataaact
    11161 tgtgagttgc caacttattt aaaaagttat atagaactag atgagatgac ccgagggagt
    11221 ataataaaga aaagagctaa ggagtgaatc atagggcata gcaacattag gagctgaacg
    11281 aggaggctaa gaaaaaagtg gccattgagg ttggaggaga aacttgagag tgccaggtct
    11341 ctgaagaagg atgaagccag ttgcatcaaa tgctgctgat atgtcaagta atatgtaaaa
    11401 taaaaatgga tatgtggatt tggaaatatg aaggatattt tttacttggt gagagtttta
    11461 atacattttt tagaaagaaa aataccttga gtaaaggaaa acaagaatga ggaagtaaag
    11521 acagaatgta taggcatatc ttttgaggaa ttttgctata aaagggaaca gataaatcag
    11581 attggtacct aaaggcagat gtgagattga gggtggggtg gagatgggaa ggtaagtgtt
    11641 agatagatat ttcagcatga atatatattg aagggaatga tccagtagac aaagaagaat
    11701 taatgatgca tatgagaaag taggcaactg caaaagcaaa gtgtttgggt aggcaagaga
    11761 gagtgggctc agtgccaaag taaaggacag gaggagcaca gactgtttat taccctaaat
    11821 aaagtgaagg caaggtatat ggatagaaat gtagtaggtt gggagatcag atattaggag
    11881 aatgaggaaa ctcaaaacca atggcttcca agttctcagg aatcaaaatc aaggacatca
    11941 gagataaagg aaagaagaag ttgttgaagc tttggccagt gggtataaga aaaagtagga
    12001 caagtggatg tatccaaggg gcatttgggg agattaaaca taatgtctaa ccaaggtaaa
    12061 aagggaagtg agtacataaa gcagtaaata gagaggttaa agaattattg acatcagcgt
    12121 acaagagaag gtcaaagagt gagatccttc agaaagagat tttgcatatg ttgcaagtaa
    12181 cgataagttc agagaataca atatcatcat aaataagact ggctgaaaat aatcataaac
    12241 ctttaaaatg catttggtaa gaagcatata cctgtaattt tttaaattca atctttacaa
    12301 tctatatttt aactggcaag atatggtcta ttttacatgt attgtaatta gtaataataa
    12361 aattatttgt aattctatta atttatttta tgctttcagt ttacccttct ttttctatgc
    12421 ttcttatttt cttctttcct ggcttctgtt gaattattaa agttctaagt tccccttttc
    12481 tactctaatg gttagaatta taaattctat tatttatgaa atacccataa acttacccaa
    12541 atacatatat cacttaacca cagcaaaatt cattaatatc taattcctct taccaaacaa
    12601 accaaggtcc aaaaatgttt tagttgtgac tgctacagta atctcccttc acattgtttt
    12661 ctacatgatt ttagtttcac ctggttttgt aagtcctaat aaagttataa ttctttatat
    12721 ggtacacact tagatttatt gacatgctta ctaatttcaa caccaatgag ataaactgaa
    12781 cattccttaa atggcaaaat gaaacccagt cagaaaaacc tttctcttta aatattgaag
    12841 agctattaaa tccatcctat acaatgaaat attataaact tcatgaaatg tttaaaaaac
    12901 aaataaaaaa ttgaatgaac tttcattgag tatcttgtca tatggctaac tggctttcag
    12961 agaattgtgt cttagcaaat taatcattta ttaagttagc ttttggggaa gtaataaaac
    13021 agtaaatttg tataagtaaa ttttactgct taaaaccagt cagcctttct aaattcttgt
    13081 tgctagcaat ggcaagatca gcaagaggga tgatcttacc tagagcacac tgaggtctgt
    13141 gagactacta agtccagctg taagtggcac aaggccaaaa aatgggcaat tttatttaag
    13201 tcaggaaaac tctattcatt tgttttatgt agatggtaga gaaaagtttc tcatgtccat
    13261 cttccattct taaagatgga ttacttagag gaaaatgtag gtttaaaacg cggaaaatga
    13321 ttgtaataat ataaccctag aaaaaaagtc gtataaaaaa gtgcattttc atttgttctt
    13381 tctaggttca catttattgc caaaagatgt ctactctcct ggttttcatc tttgccataa
    13441 ttaatctttt caacgaatat tcaaaaaaag ataaaaacac tgacacattg agtaaaaaag
    13501 agctgaagga acttctggaa aaggaatttc ggcaaatcct gaaggtaaga gtgtctgaca
    13561 agaccaaaga tagagcattt gtttttctca tcaataatct aagcaagggt tattttgagc
    13621 tctttgtgaa ctatttctct taaaatagga aaagagttaa tcttgtctca aaagagatag
    13681 attttatttt cttcccctat acctggatgt atattataaa cataaagaca ccctcagaga
    13741 aaaaaatata aatatttaaa aattaatgta aattagttct tagtattttg gtatttataa
    13801 tatctcccaa acatcaacat tactaagggg atttttgtta aagacaacta agtaatgaat
    13861 tatatacact tctgactttt aaaataagaa aaagagtcac ttaccccatc aaatcttgat
    13921 accttactag tctacatctt tgttcacata taacacctga atgaggatga gacaaaaaag
    13981 tcttaaaaaa aaaaaagatt ttgtcccact ttttaatact caaagatcag gttccttaaa
    14041 ttaactttga attaattggc tgataatgtg attctgtctg atgcagtctc cctctgtgac
    14101 ttccctctgt acagaatcca gatgacccag atatggttga tgtcttcatg gatcacttgg
    14161 atatagacca caacaagaaa attgacttca ctgagtttct tctgatggta ttcaagttgg
    14221 ctcaagcata ttatgagtct accagaaaag agaatttacc gatatcagga cacaagcaca
    14281 gaaagcacag tcatcatgat aaacatgaag ataataaaca ggaagaaaac aaagaaaaca
    14341 gaaaaagacc ctcaagtctg gaaagaagaa acaatagaaa agggaataag ggaagatcca
    14401 agagcccaag agaaacaggg gggaaaaggc atgaatctag ttctgaaaaa aaagaaagaa
    14461 aaggatattc acctactcat agagaagaag aatatggaaa aaaccatcat aactcaagta
    14521 aaaaagagaa aaacaagact gaaaatacta gattaggaga caataggaag aggctaagtg
    14581 aaagacttga agagaaagaa gacaatgaag aaggagtata tgattatgaa aatacaggaa
    14641 gaatgactca aaaatggata caatcaggcc atattgccac atattacaca atccaggatg
    14701 aagcctatga caccactgat agtctattag aagaaaacaa aatatatgaa agatcaaggt
    14761 catctgatgg caaatcatca tctcaagtga acaggtcaag acatgaaaat acaagccagg
    14821 taccattgca ggagtccagg acaagaaagc gtaggggatc cagagttagc caggacaggg
    14881 acagtgaggg acactcagaa gactctgaga ggcactctgg gtcggcttcc agaaaccatc
    14941 atggatctgc gtgggagcag tcaagagatg gctccagaca ccccaggtcc catgatgaag
    15001 acagagccag tcatgggcac tctgcagaca gctccagaca atcaggcact cgtcacgcag
    15061 agacttcctc tcgtggacag actgcatcat cccatgaaca ggcaagatca agcgcaggag
    15121 agagacatgg ctcccaccac cagcagtccg cagacagctc caggcactcc ggcatcgggc
    15181 acggccaagc ttcaactgca gtcagcgata gtggacaccg gggctacagg ggtagtcagg
    15241 caagcgacaa tgagggacat tcagaagact cagactcaca atcagtcgca ggccaaagac
    15301 aggctaggtc gagacaccag agccaccaag agtccacacg aggccggtct aggggagggt
    15361 ccggacgttc agggtctttc ctataccagg tgagcactca tgaacagtct gaatcttccc
    15421 atggatgggc caggaccagc actggcagaa gacagggctc acgccacgac caggcacaag
    15481 acagctcccg gcattctacg tcccaacaag gccaggacac cattcatgca cacccgggct
    15541 ctaggagagg aggcaggcac ggctaccacc atgagcaatc cgctgatagc actggacact
    15601 caggatccca acacagccac accacaaccc agggaagatc cgatgcctcc cgtggctcgt
    15661 caggatccag aagcacaagc agggaaaccc gggatcagga acaatctggt gacggctcca
    15721 gacactctgg ctcacatcat caagaagctt ccactcgggc tgaaagctcc aggcactctc
    15781 aggtcggcca aggagaatca tcggggtcca gaaccagcag gaaccaggga tccagtttta
    15841 gccaagacag ggacagtcag gcacaatctg aagactccga aaggaggtcc gcgtccggct
    15901 ctaggaacca tcgtggatcc gcccaagaac agtctagaga tggctccagg caccccggtt
    15961 cccatcaaga ggacagggcc ggacacaggc aatccgcaga aagctctagc cagtcaggca
    16021 cccatcacgc agagaattct agcggcggcc aagccgcttc ctctcaagaa caggcaaggt
    16081 caagcgctgg agaaagacac ggatccggcc atcagcagtc agcagacagc tccaggcact
    16141 caggcattgg gcacgggcaa gcttcatctg cagtcagaga tagtggacac cgggggtaca
    16201 gcggtagtca ggcaagcgac caagaaggac actcagaaaa ctcagactca caatcagtct
    16261 caggccaaag acaggctagg tcgcaccagc agagccacca agagtccaca cgtggccagt
    16321 ctcggggacg gtctggacgt tcagggtctt tcctatacca ggtgagcact catgaacagt
    16381 ctgaatctgc ccatggacgg tcagcgccca gcactaggag aagacaggga tcacaccacg
    16441 accaggcacg ggacagctcc aggcattcag cgtcccaaga gggtcaggac accattcgtg
    16501 gacaccccgg gtcaagcaga ggaggaaggc agggctccca ctacgagcaa tcggttgata
    16561 ggtctggaca ctcaggttcc catcacagcc acaccacatc ccagggaagg tctgatgcct
    16621 cccatgggac gtcaggatcc agaagtgcaa gcagacaaac acgggatgag gaacaatcag
    16681 gagacggcac caggcactca gggtcacatc atcaagaagc ttccactcag gctgacagct
    16741 ctaggcactc tcaggtgggc caaggacaat cagcggggtc caggacaagt aggaaccagg
    16801 gatccagtgt tagccaagac agggacagtg agggacaatc agaagactct gagaggcatt
    16861 ctggatccgc ttccaggaac catcgtggat ccgctcagga acagtcaaga gatggctcca
    16921 gacaccccgg ctcccatgac gaggacaggg ctggacacag gcaatccgca gatagctcaa
    16981 gccaatcagg cactcgtcac acgcagactt cttccaggag acaggcagct tcatcccaag
    17041 aacaggcaag atcaagggca ggtgatagac atggttccgg ccaccagcag tcagcagaca
    17101 gctccagaca ctcagccatc gggcgcggcc aagcttcatc tgcagtcaga gatcgtggcc
    17161 accggggctc aaggggtagt caggcaagcg accaagaggg acattcagaa gactctgact
    17221 cacaatcagt ctcagcccaa agacaggctg ggtcgcatca gcagagccac caagagtcca
    17281 cacgcggccg gtcacaggga aggtctggac gttcagggtc tttcatctac caggtgagca
    17341 ctcatgaaca gtctgagtct gcccatgggc ggaccaggac cagcactgga cgaagacaag
    17401 gatcccacca cgagcaggca cgagacagct ccaggcactc agcgtcccaa gagggtcagg
    17461 acaccattcg tgcacacccg gggtcaagga gaggaggaag gcagggatcc catcatgagc
    17521 aatcggtaga tagatctgga cactcagggt cccatcacag ccacaccaca tcccagggaa
    17581 ggtctgatgc ctcccatggg cagtcaggat ccgttgacct gcaggtcgac
//