From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus N-methyl-D-aspartate receptor (NMDAR1) gene,
Date: 3 Jan 93 22:18:56 GMT
Distribution: bionet
Checksum: 38851 10

LOCUS       RATNMDAR     4444 bp ds-DNA             ROD       23-DEC-1992
DEFINITION  Rattus norvegicus N-methyl-D-aspartate receptor (NMDAR1) gene,
            exons 1 through 22.
ACCESSION   L08228
KEYWORDS    N-methyl-D-aspartate receptor; glutamate receptor;
            ligand gated ion channel; transmembrane protein.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda
            GEM11/lambda Charon 4A from Eberwine) mixed neonatal liver DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 4444)
  AUTHORS   Boulter,J., Hollmann,M., O'Leary,L., Maron,C., Pecht,G.,
            Heinemann,S.F. and Sullivan,J.
  TITLE     Potentiation of NMDA responses by zinc
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    1..4444
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="NMDAR1"
     5'UTR           1..217
                     /gene="NMDAR1"
     exon            1..475
                     /number=1
                     /gene="NMDAR1"
     exon            476..610
                     /number=2
                     /gene="NMDAR1"
     exon            611..826
                     /number=3
                     /gene="NMDAR1"
                     /note="alternate exon; truncated protein"
     3'UTR           764..>764
                     /gene="NMDAR1"
                     /note="truncated protein"
     exon            827..1003
                     /number=4
                     /gene="NMDAR1"
     exon            1004..1066
                     /number=5
                     /gene="NMDAR1"
                     /note="clones NMDAR1-1b, -2b, -3b and -4b; alternate exon"
     exon            1067..1167
                     /number=6
                     /gene="NMDAR1"
     exon            1168..1289
                     /number=7
                     /gene="NMDAR1"
     exon            1290..1414
                     /number=8
                     /gene="NMDAR1"
     exon            1415..1609
                     /number=9
                     /gene="NMDAR1"
     exon            1610..1693
                     /number=10
                     /gene="NMDAR1"
     exon            1694..1835
                     /number=11
                     /gene="NMDAR1"
     exon            1836..1963
                     /number=12
                     /gene="NMDAR1"
     exon            1964..2128
                     /number=13
                     /gene="NMDAR1"
     exon            2129..2247
                     /number=14
                     /gene="NMDAR1"
                     /note="transmembrane domain 1"
     exon            2248..2360
                     /number=15
                     /gene="NMDAR1"
                     /note="transmembrane domain 2"
     exon            2361..2509
                     /number=16
                     /gene="NMDAR1"
                     /note="transmembrane domain 3"
     exon            2510..2667
                     /number=17
                     /gene="NMDAR1"
     exon            2668..2829
                     /number=18
                     /gene="NMDAR1"
     exon            2830..2939
                     /number=19
                     /gene="NMDAR1"
     exon            2940..3085
                     /number=20
                     /gene="NMDAR1"
                     /note="putative transmembrane domain 4"
     exon            3086..3196
                     /number=21
                     /gene="NMDAR1"
                     /label=EXON21
                     /note="clones NMDAR1-1a, -1b, -3a, and -3b; alternate
                     exon"
     exon            3197..4444
                     /number=22
                     /gene="NMDAR1"
                     /note="allternate exon; alternate acceptor splice site at
                     bp 3353"
     3'UTR           3314..4444
                     /gene="NMDAR1"
                     /note="clones NMDAR1-1a, -1b, -2a, and -2b; alternate
                     termination signal"
     3'UTR           3622..4444
                     /gene="NMDAR1"
                     /note="clones NMDAR1 3a, 3b, 4a, alternate termination
                     signal"
BASE COUNT      984 a   1365 c   1255 g    840 t
ORIGIN      
        1 tcgcgcagtc cgcgctgctg tcctttccgc cttttccgcg cgggtgttcg agcagcgcca
       61 aacacgcttc agcacctcgg acagcatccg ccgcgctcgc ccggggctcc tagagaaccc
      121 gggggcgctt gaccgcgcgc gggcggcccg cgggtcgtac atcgcgaggt cgtcgcactc
      181 gcgcaaccca gagccaggcc cgctgtgccc ggagctcatg agcaccatgc acctgctgac
      241 attcgccctg cttttttcct gctccttcgc ccgcgccgcc tgcgacccca agatcgtcaa
      301 catcggcgcg gtgctgagca cgcgcaagca tgaacagatg ttccgcgagg cagtaaacca
      361 ggccaataag cgacacggct cttggaagat acagctcaac gccacttctg tcacccacaa
      421 gcccaacgcc atacagatgg ccctgtcagt gtgtgaggac ctcatctcta gccaggtcta
      481 cgctatccta gttagccacc cgcctactcc caacgaccac ttcactccca cccctgtctc
      541 ctacacagct ggcttctaca gaatccctgt cctgggactg actacccgaa tgtccatcta
      601 ctctgacaag ccctctgtcc atcacacagg tcggaaagag caggcccgca gcaccaaatg
      661 taatacaagt tgcctgcagc cagttgcaga ggcggtgaac attctatccc tacaatgcac
      721 tgcccctgac caccaagagg gaaccggtaa aaaactaacc tagaagcatc agagggccaa
      781 gagcagtgtg aatcatgacg gtgcggaagg agccatgttc actcagagta tccacctgag
      841 tttccttcgc acggtgccgc cctactccca ccagtccagc gtctggtttg agatgatgcg
      901 agtctacaac tggaaccaca tcatcctgct ggtcagcgac gaccacgagg gacgggcagc
      961 gcagaagcgc ttggagacgt tgctggagga acgggagtcc aagagtaaaa aaaggaacta
     1021 tgaaaacctc gaccaactgt cctatgacaa caagcgcgga cccaaggcag agaaggtgct
     1081 gcagtttgac ccaggaacca agaatgtgac ggctctgctg atggaggccc gggaactgga
     1141 ggcccgggtc atcatccttt ctgcaagcga ggacgacgct gccacagtgt accgcgcagc
     1201 cgcaatgctg aacatgacgg gctctgggta cgtgtggctg gtcggggaac gcgagatctc
     1261 tgggaacgcc ctgcgctacg ctcctgatgg catcatcgga cttcagctca tcaatggcaa
     1321 gaatgagtca gcccacatca gtgacgccgt gggcgtggtg gcacaggcag ttcacgaact
     1381 cctagagaag gagaatatca ctgacccacc gcggggttgc gtgggcaaca ccaacatctg
     1441 gaagacagga ccattgttca agagggtgct gatgtcttct aagtatgcgg acggagtgac
     1501 tggccgtgtg gaattcaatg aggatgggga ccggaagttt gccaactata gtatcatgaa
     1561 cctgcagaac cgcaagctgg tgcaagtggg catctacaat ggtacccatg tcatcccaaa
     1621 tgacaggaag atcatctggc caggaggaga gacagagaaa cctcgaggat accagatgtc
     1681 caccagacta aagatagtga caatccacca agagcccttc gtgtacgtca agcccacaat
     1741 gagtgatggg acatgcaaag aggagttcac agtcaatggt gacccagtga agaaggtgat
     1801 ctgtacgggg cctaatgaca cgtccccagg cagcccacgc cacacagtgc cccagtgctg
     1861 ctatggcttc tgcatagacc tgctcatcaa gctggcgcgg accatgaatt ttacctatga
     1921 ggtgcacctg gtggcagatg gcaagtttgg cacacaggag cgggtaaaca acagcaacaa
     1981 aaaggagtgg aacggaatga tgggcgagct actcagtggc caagcggaca tgattgtggc
     2041 accactgacc atcaacaatg agcgtgcgca gtacatagag ttctccaagc ccttcaagta
     2101 ccagggcctg accattttgg tcaagaagga gattcccagg agcacactgg actcatttat
     2161 gcagcctttt cagagcacac tgtggttgct agtaggactg tcagttcatg tggtggctgt
     2221 gatgctgtac ctgctggacc gcttcagtcc ctttggccga ttcaaggtga acagtgagga
     2281 ggaggaggaa gatgcactga ccctgtcctc tgccatgtgg ttttcctggg gcgtcctgct
     2341 caactccggc attggggaag gtgccccccg gagtttctct gcacgtatcc taggcatggt
     2401 gtgggctggt ttcgccatga tcatagtggc ttcctacact gccaacttgg cagctttcct
     2461 ggtgctggat cggcctgagg agcgcatcac gggcatcaat gaccccaggc tcagaaaccc
     2521 ctcagacaag ttcatctacg caactgtaaa gcagagctcc gtggacatct acttccggag
     2581 gcaggtggag ttgagtacca tgtaccggca catggaaaaa cacaattacg agagcgcagc
     2641 tgaggccatc caggctgtgc gggacaacaa gctgcacgcc tttatctggg actcggccgt
     2701 gctggagttt gaggcttcac agaagtgcga tctggtgacc acgggtgagc tgttcttccg
     2761 ctcaggcttt ggcatcggca tgcgcaagga cagcccctgg aagcagaacg tttccctgtc
     2821 catactcaag tcccatgaga atggcttcat ggaagatctg gataagacat gggttcggta
     2881 tcaggaatgc gactcccgca gcaatgctcc tgcaaccctc acttttgaga acatggcagg
     2941 ggtcttcatg ctggtggctg gaggcatcgt agctgggatt ttcctcattt tcattgagat
     3001 cgcctacaag cgacacaagg atgcccgtag gaagcagatg cagctggctt ttgcagccgt
     3061 gaacgtgtgg aggaagaacc tgcaggatag aaagagtggt agagcagagc ccgaccctaa
     3121 aaagaaagcc acatttaggg ctatcacctc caccctggcc tccagcttca agagacgtag
     3181 gtcctccaaa gacacgagca ccgggggtgg acgcggcgct ttgcaaaacc aaaaagacac
     3241 agtgctgccg cgacgcgcta ttgagaggga ggagggccag ctgcagctgt gttcccgtca
     3301 tagggagagc tgagacgccc cgcccgccct cctctgcccc tcccccgcag acagacgcac
     3361 gggacagcgg cctggcccac gcagagcccc ggagcacgac ggggtcgggg gaggagcact
     3421 cccagcctcc cccaggccgt gcccgcctgc ccaccggtcg gccggctggc cggtccaccc
     3481 tgtcccggcc ccgcgcgtgc ccccgacgtc ggagctaacg ggccgccttg tctgtgtatt
     3541 tctattttac agcagtacca tcccactgat atcacgggcc cgctcaacct ctcagatccc
     3601 tcggtcagca ccgtggtgtg aggccccccg gaggcgccca cctgcccagt tagcccggcc
     3661 aaggacactg atgagtcctg ctgctcggga aggcctgagg gaagcccacc cgccccagag
     3721 actgcccacc ctgggcctcc cgtccgcctg ctctgctgcc tggcgggcag cccctgcagg
     3781 accaaggtgc ggaccagagc ggctgaggat gggccagagc tgagccggct gggcagggcc
     3841 acagggcgct ccggcagagg cagggccctg aggtctctga gcagtggggt gaggggccta
     3901 agtggccccg gtcggaggag tctggagcag aaatggcagc cccatccttc ctccagccac
     3961 taccccaagc tacagtgggg gcctatggcc ccagcttgct aggtcacccc cgacccttcc
     4021 tccagcgcct gctctctgca acttgatttc cacctctctc ctgctgcacc accctcccac
     4081 gacatttccc caccccattc actgggttgt ctctgacctt tcccagggct agccttcact
     4141 gccctagtgg cagtgcttca ggggtgcttt ctggctccca gacatctagg gctccagact
     4201 ccaagagggc tgagccttct cttctgtccg cagccacaat aggcttcctc agacgctggc
     4261 tcgtgatgag tcccgcacct tgggcaccag ggagcgccat ctgcctccca gtccggtgtc
     4321 actcacccca ctaccttgta catgaccagc tctcccagtg tcccagtgtc tgccccaggg
     4381 acaccgggcg cgcacagcca cccctaatcc cggtattcag tggtgatgcc taaaggaatg
     4441 tcag
//