From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human surfactant protein D (SP-D) gene exon 7, complete cds.
Date: 6 Nov 92 18:30:31 GMT
Distribution: bionet
Checksum: 26458 4

LOCUS       HUMSPD03      767 bp ds-DNA             PRI       02-NOV-1992
DEFINITION  Human surfactant protein D (SP-D) gene exon 7, complete cds.
ACCESSION   L05485
KEYWORDS    collagen; lectin; surfactant protein D.
SEGMENT     3 of 3
SOURCE      Homo sapiens (library: Stratagene; lambda FIX II) male placenta
            DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 767)
  AUTHORS   Rust,K., Grosso,L., Zhang,V., Chang,D., Persson,A., Longmore,W.,
            Cai,G.-Z. and Crouch,E.
  TITLE     Human Surfactant Protein D: SP-D Contains a C-Type Lectin
            Carbohydrate Recognition Domain
  JOURNAL   Arch. Biochem. Biophys. 290, 116-126 (1991)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 767)
  AUTHORS   Crouch,E., Rust,K., Veile,R., Donis-Keller,H. and Grosso,L.
  TITLE     Genomic Organization of Human Surfactant Protein D: SP-D is Encoded
            on Chromosome 10q22.2-23.1
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            290..748
                     /number=7
                     /function="lectin or carbohydrate recognition domain
                     (CRD)"
                     /gene="SP-D"
                     /evidence="EXPERIMENTAL"
                     /citation=[2]
                     /citation=[1]
     polyA_signal    749..754
                     /gene="SP-D"
     intron          order(L05484:3015..3262,1..289)
                     /number=6
                     /gene="SP-D"
     CDS             join(L05483:250..448,L05484:836..952,L05484:1213..1329,
                     L05484:1645..1761,L05484:2204..2320,L05484:2931..3014,
                     290..666)
                     /gene="SP-D"
                     /product="surfactant protein D"
                     /codon_start=1
                     /translation="MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVE
                     SGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDT
                     GPSGPPGPPGVPGPAGREGALGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARG
                     LAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGE
                     SGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTE
                     AQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVY
                     SNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF"
BASE COUNT      171 a    191 c    219 g    186 t
ORIGIN      
        1 gaattcctaa ctgcacgttt gctgcttgtg tgactttgag cctctagctt ctctaaactc
       61 cagtactctc catctgtaag tggggaatca tggtgtcacc tcacagggta ggtcatggtg
      121 gacgggggct gttctggaac aatctctctt gcattctctc tggcatcctg atgcggtgcc
      181 tgtttgggag gtctgaaagg ctcaggttgg agcacagagg tctcacagcc cctgagcttt
      241 ggccaggtga tgccacaacc ccaacctgac tttcttcttc tcctactagt tgagctcttc
      301 ccaaatggcc aaagtgtggg ggagaagatt ttcaagacag caggctttgt aaaaccattt
      361 acggaggcac agctgctgtg cacacaggct ggtggacagt tggcctctcc acgctctgcc
      421 gctgagaatg ccgccttgca acagctggtc gtagctaaga acgaggctgc tttcctgagc
      481 atgactgatt ccaagacaga gggcaagttc acctacccca caggagagtc cctggtctat
      541 tccaactggg ccccagggga gcccaacgat gatggcgggt cagaggactg tgtggagatc
      601 ttcaccaatg gcaagtggaa tgacagggct tgtggagaaa agcgtcttgt ggtctgcgag
      661 ttctgagcca actggggtgg gtggggcagt gcttggccca ggagtttggc aagaagtcaa
      721 ggcttagacc ctcatgctgc caatatctaa taaaaatgga gaccatc
//