From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.francisci germline DNA for immunoglobulin heavy chain (Vh,D1,D2,
Date: 15 Aug 92 10:01:47 GMT
Distribution: bionet
Checksum: 58957     5

LOCUS       HEFGIGHB     2019 bp ds-DNA             VRT       15-AUG-1992
DEFINITION  H.francisci germline DNA for immunoglobulin heavy chain (Vh,D1,D2,
            Jh)
ACCESSION   Z11777
KEYWORDS    Ig D-segment; heavy chain; immunoglobulin; joining region;
            variable region.
SOURCE      Heterodontus francisci DNA.
  ORGANISM  Heterodontus francisci
            Eukaryota; Animalia; Chordata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Euselachii; Neoselachii; Galeomorphii;
            Heterodontiformes; Heterodontidae.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Litman,G.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Hinds-Frey,K.R., Nishikata,H., Litman,R.T. and Litman,G.W.
  TITLE     Multiple somatic mechanisms are employed to generate immunoglobulin
            heavy chain diversity in a primitive vertebrate
  JOURNAL   J. Exp. Med. (1992) In press
  STANDARD  full staff_review
COMMENT
            From EMBL    entry HFGIGHB;  dated 06-AUG-1992.
FEATURES             Location/Qualifiers
     misc_feature    287..577
                     /function="variable region"
                     /standard_name="Vh"
     misc_recomb     581..587
                     /organism="Heterodontus francisci"
     misc_feature    1036..1050
                     /function="Diversity region"
                     /standard_name="D1"
     misc_feature    1426..1438
                     /function="Diversity region"
                     /standard_name="D2"
     misc_feature    1831..1877
                     /function="joining region"
                     /standard_name="Jh"
BASE COUNT      573 a    388 c    453 g    605 t
ORIGIN
        1 ggtatttaaa tgctgctcac tgggatcgca atacaacagt ccgggagcgg gtttactcac
       61 tgagttcttg ccagaattat ttcccccgaa ttgctagtag gatgaggtcg gcgatttctc
      121 tcagtctatt gttggttttc ttatcccgtg agtagttttt attgtcccag tctctcactg
      181 ttactgtctc aatgttcgtc tctctctgga atgttacaga ttcaggagtc atttcaccag
      241 gattaatcct cagggttttt aatatttttt tacaggtgtc cagtcggata tcgtgttgac
      301 tcagccagaa gcagacaccg ggaaacccga aggctccctg agactgacct gtaaaaccag
      361 cgggttcagt cttggcagct actatatgac ctgggtccga caggttcccg ggcaggggct
      421 ggagtggttg gttagctacc atagttcatc ataccagtac tacgcccctg agattaagga
      481 tcgatttact gcgtccaaag acacttcaaa caacatcttc gctttggaca tgaagagcct
      541 gaagaccgaa gacactgcca tgtattactg tgcaagagac cacagcgaga ggaaccaggg
      601 ctggacccgt acaagaacag gtcgagaggg aattggacaa attccatcat aacctgacgg
      661 tcagtaattg tattaaatgt aatattaacg gcagtgttca gaaccagacc atataccgtt
      721 tcttacaaaa ctaacacagt gaaaattcaa tggtgaaaat ctaagacact gagcgatgta
      781 ttgatgagca attttggcta tgctgatttt taatgttaac agtgtcagca attgcagacc
      841 tagataagat gatagcttca atgtgactga tgatacctgg agagagttac ttggagacac
      901 tacctactgc gtggtgtaaa cctttggata tattctgaac tagatcagat gtgaatttct
      961 atttgaagag aatggtgata ggcagtagtg aacagagatt gagtgcagta tttgtacagc
     1021 tttgaagtca ctgtgggtac agcggtgggt cacggtgctg tacagagcga gttcctcata
     1081 caaaaacccc agactgggag tttgctcaaa cctgcgatca ctaccactgc agatgggccg
     1141 taaacaatga ggattaaata aaaataatgg ggaaacgtga tatagatttc taaaaatgta
     1201 taaaagtctc ctgctttctt attgttgaca cgttaaatca gcacagctgc ttcagaagta
     1261 ttccaatcca cgttataacc ataataacct gtacaaactg atttatctca ctgatgtact
     1321 ctaaagggaa tctggatcag gtttatgaga gcacggtgga atttaatctc tgtactttac
     1381 agttagcagt ccgcctcagt atttgacacg gtgtgtctca ctgtgatata ctggatggca
     1441 cagcagttac tgtcagtaca aaaagtccct cagtactaat tgatgagtct gagtcaatac
     1501 tcggttttac agtccaactg tatatgcagt gaagttctat ttgtgtccag cactgtccta
     1561 ttagcacggt ttcttatgga taaactgata attattcatt caccagctgg tgatttcaat
     1621 aattgctggt atgtgactgt gtgaaatata aaacatcagg gaaatttata aagagtgaaa
     1681 agaatcatta acacagttat aattttacga agcaccatca tcattttatt ttgcctctgg
     1741 gcgatggata tttaaaataa tgaaggattt ccctctattc tgtgcagagc tggttattgt
     1801 ctgaaccagc ccggggaatg taacactgtg actatctcga ctactgggga caagggacca
     1861 tggtgacggt gactgcaggt aagaactatg cactgattca gtaactgatt tatttgtgtt
     1921 ttattttata tttctgttta ttttaatgac acgttcgttc actgacatgt ggaatcggtg
     1981 gattctgtat tgagatttgt tgcacagttt catgcgatt
//