From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: 2',3'-cyclic nucleotide-3'-phosphohydrolase [human, Genomic, 1042
Date: 6 Jan 93 06:58:13 GMT
Distribution: bionet
Checksum: 55669 4

LOCUS       M251984S4    1042 bp    DNA             PRI       17-DEC-1992
DEFINITION  2',3'-cyclic nucleotide-3'-phosphohydrolase [human, Genomic, 1042
            nt, segment 4 of 4] 
ACCESSION   S46849
KEYWORDS    .
SEGMENT     4 of 4
SOURCE      human
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Thompson,R.J.
  TITLE     2',3'-cyclic nucleotide-3'-phosphohydrolase and signal transduction
            in central nervous system myelin.
  JOURNAL   Biochem. Soc. Trans. 20, 621-626 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 116972] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 1.  Map location: 17q21.
FEATURES             Location/Qualifiers
     CDS             join(S46843:127..129,S46845:10..682,S46846:10..149,
                     10..459)
                     /note="mismatches(195[Y->T],344[Y->T]).  CNPase;  For the
                     protein sequence (NCBI gibbsq 116974):  Method: conceptual
                     translation supplied by author.  This sequence comes from
                     Fig. 1.
                     Author-given protein sequence is in conflict with the
                     conceptual translation"
                     /product="2',3'-cyclic nucleotide-3'-phosphohydrolase"
                     /codon_start=1
                     /translation="MNRGFSRKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVA
                     TLLECKTLFILRGLPGSGKSTLARVIVDKYRDGTKMVSADAYKITPGARGAFSEEYKR
                     LDEDLAAYCRRRDIRILVLDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQ
                     LKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLYKKSSETLRKAGQVFLEELGNHKA
                     FKKELRQFVPGDEPREKMDLVTYFGKRPPGVLHCTTKFCDYGKAPGAEEYAQQDVLKK
                     SYSKAFTLTISALFVTPKTTGARVELSEQQLQLWPSDVDKLSPTDNLPRGSRAHITLG
                     CAADVEAVQYGLDLLEILRQEKGGSRGEEVGELSRGKLYSLGNGRWMLTLAKNMEVRA
                     IFTGYYGKGKPVPTQGSRKGGALQSCTII"
BASE COUNT      221 a    289 c    302 g    230 t
ORIGIN      
        1 tctccccagg tgttaaagaa atcttactcc aaggccttca cgctgaccat ctctgccctc
       61 tttgtgacac ccaagacgac tggggcccgg gtggagttaa gcgagcagca actgcagttg
      121 tggccgagtg atgtggacaa gctgtcaccc actgacaacc tgccgcgggg gagccgcgcc
      181 cacatcaccc tcggctgtgc agctgacgta gaggccgtgc agacgggcct tgacctctta
      241 gagattctgc ggcaggagaa ggggggcagc cgaggcgagg aggtgggcga gctaagccgg
      301 ggcaagctct attccttggg caatgggcgc tggatgctga ccctggccaa gaacatggag
      361 gtcagggcca tcttcacggg gtactacggg aaaggcaaac ctgtgcccac gcaaggtagc
      421 cggaaggggg gcgccttgca gtcctgcacc atcatatgag tgttctcacc accacttatg
      481 cccctagaag ggaaggggag agggaaacgt gccctctgtt tgatccttgt tttgtgacat
      541 tttttttttt tttttttttt actcaaagtt aacctacctg taacttttta aaaacttgta
      601 aaataactga ccctcccttc ctgtccgccc tcttcccctc taatgctcac gctcccaaca
      661 caaggtgggc agggaggcac cattcaggag cctggaccaa agctgacgag gctgggccaa
      721 gccagggatg gggccacagc cagaaccccg agccctactt ccaggttctg gttagctcag
      781 ccccagccca gcccagctgc tctgcccaga gctgggtgag tgggcagaca cctcagagcc
      841 ccgcaaaacc cactgaccgg aggcaaaagg cagtggggct gggggtagtt ttccatggtc
      901 acagagaact agtggtggct ctgagaaggg gaggacctct gggctttgat tccatctcct
      961 tgtctttttt ctttgttttt agagacaggg tcctgctatt tcccaagctg gagtgcagtg
     1021 gtgcgatcat ggctcactgc ag
//