From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human pM5 protein (pM5) mRNA, complete cds.
Date: 10 Apr 92 10:06:35 GMT
Distribution: bionet
Checksum: 17924     9

LOCUS       HUMPM5A      4086 bp ss-mRNA            PRI       10-APR-1992
DEFINITION  Human pM5 protein (pM5) mRNA, complete cds.
ACCESSION   X57398
KEYWORDS    collagenase; pM5 protein.
SOURCE      Homo sapiens (library: Okayama-Berg A2058) cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4086)
  AUTHORS   Templeton,N.S., Rodgers,L.A., Levy,A.T., Ting,K.-L., Krutzsch,H.C.,
            Liotta,L.A. and Stetler-Stevenson,W.G.
  TITLE     Cloning and characterization of a novel human cDNA that has DNA
            similarity to the conserved region of the collagenase gene family
  JOURNAL   Genomics (1992) In press
  STANDARD  full staff_entry
COMMENT     From EMBL    entry HSPM5;  dated 24-MAY-1991.
FEATURES             Location/Qualifiers
     mRNA            1..4086
                     /gene="pM5"
                     /evidence=EXPERIMENTAL
     CDS             139..3573
                     /note="the 5' untranslated region is in the same reading
                     frame as the coding region"
                     /product="pM5 protein"
                     /gene="pM5"
                     /codon_start=1
                     /translation="MIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGGDI
                     NFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
                     YEILATHPTWALKEASTTVSVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLF
                     SSLVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYR
                     GERITFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQ
                     IKVKTKADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIIATGFSVCG
                     QISIIRFPDTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPE
                     AETRAGLTLKPQTFPLTVTNRPMMDVAFVQFLASVSGKVSCLNTCGDLLVTLQSLSRQ
                     GEKRSLQLSGKVNAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDMSAVEFR
                     QTGYMLRCSLSHAITLEFYQDGNGRENVGIYSLFKGVNRFCLSKPGVYKVTPRSCHRF
                     EQAFYIYDTSSPSIFTLTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSV
                     QELRREQQLAEIEARRQEREKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSG
                     EKITVTPSSKELLFYPPSMEAVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVI
                     SEKGASSPLITVFTDDKGAYSVGPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALA
                     GVSFEIKAEDDQPLPGVLLSLSGGLFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFR
                     FEPSSQMIEVQEGQNLKITITGYRTAYSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYG
                     EDTVTDEEGKFRLRGLLPGCVYHVQLKAEGNDHIERALPHHRVIEVGNNDIDDVNIIV
                     FRQINQFDLSGNVITSSEYLPTLWVKLYKSENLDNPIQTVSLGQSLFFHFPPLLRDGE
                     NYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHTTLIFNPTRKLPEQDIAQGSYIALPL
                     TLLVLLAGYNHDKLIPLLLQLTSRLQGVRALGQAASDNSGPEDAKRQAKKQKTRRT"
                     /partial
     polyA_signal    4042..4049
                     /gene="pM5"
BASE COUNT     1031 a   1023 c   1046 g    986 t
ORIGIN
        1 cgcgacctcg tggtgggctg cggtggcttc gtcaagtcgg acgtggagat caactactct
       61 ctcatcgaga taaagctgta caccaagcat gggactttga aataccagac agactgtgcc
      121 cctaataatg gttactttat gatccctttg tatgataagg gggatttcat tctgaagatt
      181 gagcctcccc tagggtggag ttttgagccg acgaccgtgg agctccatgt ggatggagtc
      241 agtgacatct gcacaaaggg tggggacatc aactttgtct tcactgggtt ctctgtgaat
      301 ggcaaggtcc tcagcaaagg gcagcccctg ggtcctgcgg gagttcaggt gtctctgaga
      361 aacactggga ccgaagcaaa gatccagtcc acagttacac agcctggcgg aaagtttgca
      421 ttttttaaag ttctgcctgg agattatgaa atcctcgcaa ctcatccaac ctgggcgttg
      481 aaagaggcaa gcaccacagt gagtgtaacc aactccaatg ccaatgcggc cagtcccctc
      541 atagttgctg gctacaatgt gtctggctct gtccgaagtg atggggagcc catgaaaggc
      601 gtgaagtttc ttctcttttc ttctttagta actaaagagg atgtcctggg ctgcaatgtc
      661 tcaccagtgc ctgggttcca gccccaagac gagagtctgg tgtatttgtg ctacacggtc
      721 tccagagaag atggctcgtt ctctttctat tccttgccaa gtgggggcta cactgtgatt
      781 ccgttctatc gaggggagag gattaccttt gatgtggcgc cttccagact tgacttcaca
      841 gtggagcatg acagcttgaa aatcgagccc gtgttccacg tcatgggatt ctccgtcacc
      901 gggagggtct tgaacggacc cgaaggagat ggtgttccag aagcagtagt caccctgaat
      961 aaccaaatca aagttaaaac aaaagctgat ggctcattcc gccttgagaa cataaccaca
     1021 gggacataca ccatccatgc tcagaaagag cacctctact ttgaaacggt caccatcaaa
     1081 attgcaccga acacacctca gctggctgac attattgcaa cagggttcag tgtctgtggt
     1141 cagatatcaa tcattcgctt ccccgacacc gtcaagcaga tgaataaata caaagttgtc
     1201 ctgtcatctc aagacaagga caagtctttg gtcaccgtgg agacagatgc tcatggatca
     1261 ttttgtttta aagcaaaacc agggacttac aaagtgcagg tgatggttcc tgaggcagaa
     1321 accagagcag ggctgacgtt gaaaccccag acatttcctc ttactgtgac caacaggccc
     1381 atgatggatg tggcctttgt acagttcttg gcatcagttt ctgggaaagt ctcttgcttg
     1441 aacacctgtg gtgacttgct ggtgactcta cagtccctga gccgccaggg tgagaagcgg
     1501 agcctccagc tctccggcaa ggtcaacgcc atgactttca cctttgacaa cgtgctccct
     1561 ggaaaataca aaataagcat catgcatgag gattggtgct ggaagaacaa gagcctggag
     1621 gtggaagtgc tggaggatga catgtctgca gttgagttca ggcagacggg ctacatgctg
     1681 agatgttccc tgtctcacgc catcactctg gaattttatc aggatggaaa tgggcgtgag
     1741 aatgtgggga tttatagcct cttcaaagga gtcaaccgat tctgcctgtc caagcctggt
     1801 gtgtacaaag tgacccctcg ctcctgccac cggtttgagc aagcgttcta tatctatgac
     1861 acgtcttcac ctagtatctt tacattgaca gccattcgcc accatgtcct tggaactatc
     1921 accaccgaca aaatgatgga tgtcactgtg actatcaagt cttccatcga cagtgaaccc
     1981 gccttggtct taggccctct gaagtctgtg caggagctgc ggagggagca gcagctggct
     2041 gagatcgagg cccgcaggca ggagagggag aaaaacggca atgaggaagg cgaagaaaga
     2101 atgaccaagc ctcccgtgca ggagatggta gatgagttac aaggcccctt ctcgtatgat
     2161 ttctcttact gggcgcggtc tggagagaaa atcactgtta caccgtcatc taaagagctg
     2221 ctcttttatc ccccttcaat ggaagccgtt gtcagtggag aaagctgccc agggaagctg
     2281 atcgagatcc atgggaaggc aggcctgttt ttagaaggcc agatccaccc cgagttggaa
     2341 ggagtcgaga ttgtcatcag tgaaaagggg gcaagttcac cgctgatcac agtctttact
     2401 gatgacaaag gtgcctacag tgttggcccc ctgcacagtg acctggagta cacggtgacc
     2461 tcacagaagg agggctatgt tctgactgcg gtggaaggaa ccatcggaga cttcaaggcc
     2521 tatgccctgg caggcgtaag ctttgagata aaagctgagg atgaccagcc cctcccggga
     2581 gtcctcttat ccctgagcgg tggcctgttt cgttccaacc tcttgaccca ggacaacggc
     2641 attctgacat tctcaaacct gagccctggc cagtattact tcaaacccat gatgaaggag
     2701 ttccggtttg agccatcctc acagatgatc gaggtgcagg aaggccagaa cctgaagatc
     2761 accatcacgg ggtaccgaac cgcttacagt tgctatggca cagtgtcttc cttaaacgga
     2821 gagcccgaac aaggggttgc catggaagcg gtgggccaga acgactgcag catttacgga
     2881 gaagacaccg tgacagacga agagggcaag ttcagattac gtggattgct gccgggatgt
     2941 gtgtaccacg ttcagctcaa ggcagaaggc aacgaccaca ttgagcgggc gctcccccac
     3001 catagggtga ttgaggttgg gaataatgac atcgatgatg taaacatcat agttttccgg
     3061 cagattaatc aatttgattt aagtggaaat gtgatcactt cctctgaata ccttcctaca
     3121 ttatgggtca agctttacaa aagcgaaaac ctcgacaatc caatccagac agtttccctt
     3181 ggccagtccc tgttcttcca tttcccccca ctgctcagag acggcgagaa ctatgttgtg
     3241 cttctggact ccacactccc cagatcccag tatgactaca tcttgcctca agtttctttc
     3301 accgcagtgg gctaccataa acacaccacc ttgattttta atcccacgag gaagctgcct
     3361 gaacaggaca tcgcacaagg atcctacatt gccctgccat tgacgctgct ggttctgctg
     3421 gccggttaca accatgacaa gctcattcct ttgctgctgc agttgacaag ccggctacag
     3481 ggagtccgcg cgctcggcca ggcagcctct gacaatagcg gcccagaaga tgcaaagaga
     3541 caagccaaga aacagaagac aaggcggact tgaggaggaa ggggacagtt gcagtctcac
     3601 ttgggacagg ccacagccag gggtccggcc actacccgcc cgtgggataa aagccaaaag
     3661 catgcgtcag ctaacttcag cctgtgctgc tgggcccgca ccccatgtcc cttgtcactg
     3721 tgacatcctg cacccatcct cacccctccg tagagcccct cgtgcaatgc aatgaatgga
     3781 ccctcctgtc actctgctga acagaattta ttttctgagt caaatataat ttattattat
     3841 tttcgtcaaa gaagtattta agctgtgctg tggtgtgaga atgtcattct tgatcttcag
     3901 ccttcgtttg caaggagagt tccagttgac gtggtgtttg gttccatggc ggggtaccct
     3961 ggggattcat ctgttttctt cacttccctt tgcatctgag atcctgttgg aaaccacagc
     4021 aacctgtatt cattattagg aaataaaaat cgaaaaaaag gttcattctt ttgtgttgta
     4081 gttttg
//