From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Oryctolagus cuniculus Na/H exchanger 3, (NHE-3) mRNA, complete cds.
Date: 21 Jul 92 10:07:59 GMT
Distribution: bionet
Checksum: 05868     6

LOCUS       RABNAHEX     2748 bp ss-mRNA            MAM       21-JUL-1992
DEFINITION  Oryctolagus cuniculus Na/H exchanger 3, (NHE-3) mRNA, complete cds.
ACCESSION   M87007
KEYWORDS    Na/H exchanger 3; membrane transport protein.
SOURCE      Oryctolagus cuniculus ileum cDNA to mRNA.
  ORGANISM  Oryctolagus cuniculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Lagomorpha; Leporidae.
REFERENCE   1  (bases 1 to 2748)
  AUTHORS   Tse,C.-M., Brant,S.R., Walker,M.S., Pouyssegur,J. and Donowitz,M.
  TITLE     Cloning and sequencing of a rabbit cDNA encoding an intestinal and
            kidney-specific Na+/H+ exchanger isoform (NHE-3)
  JOURNAL   J. Biol. Chem. 267, 9340-9346 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             212..2710
                     /product="Na/H exchanger 3"
                     /gene="NHE-3"
                     /codon_start=1
                     /translation="MSGRGGCGPCWGLLLALVLALGALPWTQGAEQEHHDEIQGFQIV
                     TFKWHHVQDPYIIALWVLVASLAKIVFHLSHKVTSVVPESALLIVLGLVLGGIVLAAD
                     HIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFSNLGSILLYAVVGTVWNAATTGLS
                     LYGVFLSGIMGELKIGLLDFLLFGSLIAAVDPVAVLAVFEEVHVNEVLFIIVFGESLL
                     NDAVTVVLYNVFQSFVTLGGDKVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTR
                     FTKHVRVIEPGFVFIISYLSYLTSEMLSLSSILAITFCGICCQKYVKANISEQSATTV
                     RYTMKMLASGAETIIFMFLGISAVDPLIWTWNTAFVLLTLLFVSVFRAIGVVLQTWLL
                     NRYRMVQLELIDQVVMSYGGLRGAVAFALVALLDGNKVKEKNLFVSTTIIVVFFTVIF
                     QGLTIKPLVQWLKVKRSEHREPKLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWAN
                     FDRRFLSKLLMRQSAQKSRDRILNVFHELNLKDAISYVTEGERRGSLAFIRSPSTDNM
                     VNVDFSTPRPSTVEASVSYLLRESASAVCLDMQSLEQRRRSVRDAEDVITHHTLQQYL
                     YKPRQEYKHLYSRHVLSPSEDEKQDKEIFHRTMRKRLESFKSAKLGLGQSKKATKHKR
                     ERERAQKRRNSSVPNGKLPLDSPAYGLTLKERELELSDPEEAPDYYEAEKMSGGIEFL
                     ASVTKDTTSDSPAGIDNPVFSPDEDLAPSLLARVPPWLSPGEAVVPSQRARVQIPYSP
                     GNFRRLAPFRLSNKSVDSFLLAEDGAEHPESTHM"
BASE COUNT      477 a    913 c    850 g    508 t
ORIGIN
        1 ggggcctcct cggggtctga aagttccagc tctctctcct taagggtgag gccgtagcga
       61 gggctgtcca ggggcagctt cccgttgggg actgccgcct caccggctcg cgcaaggctt
      121 cacgccgccc acgcgcgtcc cgcggcctcg cgcagaggga ccctccccac gcgacatgcg
      181 cgtcgggccc cggcgctgag cggcagaggc gatgtcaggg cgcgggggct gcggcccttg
      241 ctgggggttg ctgctggcgc tggtgctggc gctgggcgcg ctgccctgga cgcagggcgc
      301 cgagcaggag catcacgatg agatccaggg cttccagata gtcacgttca aatggcacca
      361 cgtccaggac ccctacatca tcgcgctctg ggtcctcgtg gccagcttgg ctaagatcgt
      421 cttccacctg tcccacaaag tcaccagtgt cgtccccgag agcgcgctgc tcatcgtgct
      481 aggcctggtg ctaggcggca tcgtcctggc cgctgaccac atcgcctcct tcacgctcac
      541 gcccaccgtc ttcttcttct acctgctgcc gcccatcgtg ctggacgccg gctacttcat
      601 gcccaaccgg ctcttcttca gcaacctggg cagcatcctg ctctacgccg tcgtgggcac
      661 cgtgtggaac gcggccacca ccgggctgtc gctctacgga gtcttcctca gcggcatcat
      721 gggcgaactg aagatcggcc tcctggactt cctgctgttc ggcagcctca ttgctgccgt
      781 ggaccccgtg gccgtgctgg ccgtgttcga ggaggtccac gtcaacgagg ttctgttcat
      841 catcgttttc ggggagtcgc tgctaaacga cgccgtcacg gtggtgctgt acaacgtgtt
      901 ccaatctttc gtgacactgg gtggtgacaa ggtgacaggc gtggactgtg tgaagggcat
      961 agtgtccttc ttcgtggtga gcctgggggg cacgctggtg ggggtggtct tcgccttcct
     1021 gctgtcgctg gtgacgcgct tcaccaagca cgtgcgcgtc atcgagcccg gcttcgtctt
     1081 catcatctcc tacctgagct acctgacgtc cgagatgctg tccctgtcgt ccatcctggc
     1141 tatcaccttc tgcggcatct gctgtcagaa gtatgtgaaa gccaacatct cggagcagtc
     1201 ggccaccacg gtgcgctaca ccatgaagat gctggccagc ggggctgaga ccatcatctt
     1261 catgttcctg ggcatctcgg ccgtggaccc gctcatctgg acctggaaca cggccttcgt
     1321 gctgctcacg ctgctcttcg tgtccgtgtt ccgggccatc ggtgtcgtgc tgcagacctg
     1381 gctgctgaac cggtaccgca tggtgcagct ggagctgatc gaccaggtgg tcatgtccta
     1441 cggcggcctg cgcggggccg tggccttcgc cctggtcgcg ctgctggacg ggaacaaggt
     1501 caaggagaag aacttgttcg tcagcaccac catcatcgtc gtcttcttca ccgtcatctt
     1561 ccagggcctg accatcaagc cgctggtgca gtggctgaag gtgaagcgca gcgagcaccg
     1621 ggagcccaag ctgaacgaga agctgcacgg ccgggctttc gaccacatcc tctcggccat
     1681 cgaggacata tccgggcaga ttgggcacaa ttatctcagg gacaagtggg ccaacttcga
     1741 ccggaggttc ctcagcaaac tgctcatgag gcagtcggcc cagaagtctc gggaccggat
     1801 tctgaacgtg ttccacgagc tgaacctgaa ggatgccatc agctacgtga ccgagggaga
     1861 gcgccgaggc tccctggcct tcatccgctc cccgagcact gacaacatgg tcaatgtgga
     1921 cttcagcacg ccgcgcccgt ccaccgtgga ggcctccgtc tcctacctcc tgagggagag
     1981 tgccagcgcc gtgtgcctgg acatgcagtc gctggagcag cggcggcgca gcgtgcgcga
     2041 cgcagaggac gtcatcacgc accacacgct gcagcagtac ctgtacaagc ctcggcagga
     2101 gtacaaacac ctgtacagcc ggcacgtgct cagccccagc gaggacgaga agcaggacaa
     2161 ggagatcttc caccgcacca tgcgcaagcg gctggagtcc ttcaagtcgg ccaagctggg
     2221 cctcggccag agcaagaagg cgaccaagca caagcgggag cgggagcggg cgcagaagcg
     2281 gagaaacagc agtgtcccca acgggaagct gcccctggac agccctgcct acggcctcac
     2341 ccttaaggag agagagctgg aactttcaga ccccgaggag gcccccgact actacgaggc
     2401 tgagaagatg agtgggggga tcgagttcct ggccagcgtc accaaggaca cgacctccga
     2461 ctcccctgca ggaattgaca accctgtgtt ctccccggac gaggacctgg cccccagcct
     2521 cctggccagg gtgccaccct ggctgtctcc cggggaggcc gtggtgccct cccagagggc
     2581 ccgcgtgcag atcccctact ccccgggcaa cttccgccgc ctggcgccct tccggctcag
     2641 caacaagtcg gtggactcgt tcctgctggc ggaggacggc gctgaacacc ccgagtccac
     2701 acacatgtga cacgggctcc gacacgccgc tgaccggacg ctcgtccc
//