From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: (R)-3-hydroxybutyrate dehydrogenase [human, heart, mRNA, 1357 nt]
Date: 22 Dec 92 22:47:05 GMT
Distribution: bionet
Checksum: 23978 4

LOCUS       S109584      1357 bp    mRNA            NLM       23-NOV-1992
DEFINITION  (R)-3-hydroxybutyrate dehydrogenase [human, heart, mRNA, 1357 nt]
ACCESSION   S40989 M93107
KEYWORDS    .
SOURCE      human heart
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Marks,A.R., McIntyre,J.O., Duncan,T.M., Erdjument-Bromage,H.,
            Tempst,P. and Fleischer,S.
  TITLE     Molecular cloning and characterization of (R)-3-hydroxybutyrate
            dehydrogenase from human heart.
  JOURNAL   J. Biol. Chem. 267, 15459-15463 (1992)
  STANDARD  full automatic
COMMENT     This entry incorporates information provided by the National
            Library of Medicine's GenInfo Backbone as NCBI gibbsq 109584.
            This sequence comes from Fig. 2.
FEATURES             Location/Qualifiers
     CDS             1..1032
                     /partial
                     /note="Only a portion of leader peptide is shown.  BDH;
                     For the protein sequence (NCBI gibbsq 109585):  This
                     sequence comes from Fig. 2.  The authors begin their
                     numbering at -65.  Zero is not present in the numbering."
                     /product="(R)-3-hydroxybutyrate dehydrogenase"
                     /codon_start=1
                     /translation="GLRPPPPGRFSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRR
                     TYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL
                     NSDRLRTVQLNVFRSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTFGEVEFTSLET
                     YKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAF
                     SDCLRYEMYPLGVKVSVVEPGNFIAATSLYNPESIQAIAKKMWEELPEVVRKDYGKKY
                     FDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPG
                     AISDMIYIR"
BASE COUNT      327 a    362 c    375 g    293 t
ORIGIN      
        1 ggcctgcggc ctccgccacc cggacgcttc tcacggctcc caggaaaaac cctaagtgcc
       61 tgtgatagag aaaatggagc aagacgccca ctattgcttg gttctacttc ctttatcccg
      121 attggccgtc ggacttatgc cagtgcggcg gagccggttg gcagcaaagc tgtcctggtc
      181 acaggctgtg actctggatt tgggttctca ttggccaagc atctgcattc aaaaggcttc
      241 cttgtgtttg ctggctgctt gatgaaggac aaaggccatg atggggtcaa ggagctggac
      301 agcctaaaca gtgaccgatt gagaaccgtc cagctcaatg tcttcagaag cgaagaggtg
      361 gagaaagtgg tgggagattg tccgttcgag cctgaaggac ctgagaaagg catgtggggg
      421 ctcgttaaca atgccggcat ctcaacgttc ggggaggtgg agttcaccag cctggagacc
      481 tacaagcagg tggcagaagt gaacctttgg ggcacagtgc ggatgacgaa atcctttctc
      541 cccctcatcc gaagggccaa aggccgcgtc gtcaatatca gcagcatgct gggccgcatg
      601 gccaacccgg cccgctcccc gtactgcatc accaagttcg gggtagaggc tttctcggac
      661 tgcctgcgct atgagatgta ccccctgggc gtgaaggtca gcgtggtgga gcccggcaac
      721 ttcatcgctg ccaccagcct ttacaaccct gagagcattc aggccatcgc caagaagatg
      781 tgggaggagc tgcctgaggt cgtgcgcaag gactacggca agaagtactt tgatgaaaag
      841 atcgccaaga tggagaccta ctgcagcagt ggctccacag acacgtcccc tgtcatcgat
      901 gctgtcacac acgccctgac cgccaccacc ccctacaccc gctaccaccc catggactac
      961 tactggtggc tgcgaatgca gatcatgacc cacttgcctg gagccatctc cgacatgatc
     1021 tacatccgct gaagagtctc gctgtggcct ctgtcaggga tccctggtgg aaggggaggg
     1081 ggagggagga acccatatag tccgactctt gattatccac gtgtggatta tccaccatgc
     1141 caggaagacc cataactggt ttttaacact aactagaggg aatgacttct ttgcatagtg
     1201 agtgacttgg gccttcacaa acagggtgtg gagtggcagg cagaggcctc taaatctcag
     1261 gacaaacatg gtgaatctat ctctccggag ataatttcat acagagattt taagaaaaca
     1321 tctttatatt aaaaacagat ctcatttgat ccttaag
//