From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.norvegicus mRNA for gephyrin
Date: 21 Jul 92 10:08:04 GMT
Distribution: bionet
Checksum: 23165     7

LOCUS       RATGPHYRN    3392 bp ss-RNA             ROD       21-JUL-1992
DEFINITION  R.norvegicus mRNA for gephyrin
ACCESSION   X66366
KEYWORDS    gephyrin; glycine receptor; tubulin-binding protein.
SOURCE      Rattus norvegicus RNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3392)
  AUTHORS   Prior,P., Schmitt,B., Grenningloh,G., Pribilla,I., Multhaup,G.,
            Beyreuther,K., Maulet,Y., Werner,P., Langosch,D., Kirsch,J. and
            Betz,H.
  TITLE     Primary structure and alternative splice variants of gephyrin, a
            putative glycine receptor - tubulin linker protein
  JOURNAL   Neuron (1992) In press
  STANDARD  full automatic
COMMENT     *source: strain=wistar; *source: tissue=brain; *source:
            clone_library=lambda gt10, lambda gt11, lambda ZAP; *source: clone=
            p1, p5, p7;
            From EMBL    entry RNGPHYRN;  dated 10-JUN-1992.
FEATURES             Location/Qualifiers
     CDS             274..2484
                     /note="Glycine receptorassociated. Tubulin binding"
                     /product="Gephyrin"
                     /codon_start=1
                     /translation="MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQ
                     DPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKE
                     VIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILP
                     ALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEE
                     KKDSGVASTEDSSSSHITAAALARKIPDSIISRGVQVLPRDTASLSTTPSESPRAQAT
                     SRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVL
                     EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGE
                     SQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQ
                     ARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGN
                     ELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRAD
                     VIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFAL
                     PGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHH
                     QEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL"
     polyA_signal    3187..3192
     polyA_signal    3255..3260
     polyA_signal    3318..3323
BASE COUNT      996 a    810 c    746 g    840 t
ORIGIN
        1 agaacataat tcaatccggt cagcacctcc tctttctgca ttcacagcag actccaccga
       61 atccacgcac acttccataa gaaatccatt tcctgctccc gccttccccg acgatatcca
      121 cgcctgtttc cgctcggccc cctccttccc gctcgcctcg cgctccccgg gcgccctcgt
      181 tctcgcgctc tccaaggcaa gcgcgctccc ggccggcgcg tccgggctcc gcttctcccg
      241 gctcctgtca gtgcggtgat tgcgctggga aacatggcga ccgagggaat gatcctcaca
      301 aaccacgacc atcaaatccg tgtcggagtc ctcacagtga gtgatagctg cttcaggaat
      361 cttgcagaag accgcagtgg gataaatcta aaagatctcg tccaggatcc ttctttgttg
      421 ggtgggacta tatcagcata caagatagta ccagatgaaa tagaagaaat caaggaaaca
      481 ctcatagact ggtgtgatga gaaggaactt aatttgatat taacaactgg cggaacaggg
      541 tttgcaccac gagatgtcac tccagaggcc acaaaagaag taatagaacg ggaagcgcca
      601 gggatggccc tggcaatgct gatgggatca cttaatgtta cacctctggg catgctctct
      661 agaccagtgt gtggaataag agggaaaact ctgataatta acctgcctgg tagcaagaaa
      721 ggatctcagg aatgctttca gttcatactg ccagctctac ctcatgccat tgacctttta
      781 cgtgatgcca ttgtaaaagt aaaggaggtg catgatgaac ttgaagattt accttcccca
      841 ccacctcctc tttctccacc tcctacaact agcccacata agcagacaga agacaaagga
      901 gttcagtgtg aagaggagga agaagaaaag aaagacagtg gtgtagcttc gacagaagat
      961 agttcctcat cacatattac tgcagcagct cttgctcgaa agattccaga ctccatcatt
     1021 tctcgtggcg ttcaggtgct cccacgagac acagcctccc ttagcactac tccttcagag
     1081 tcgccccgtg cccaggctac atctcgcctc tctacagctt cttgtccaac accaaaagtc
     1141 cagtccaggt gcagcagcaa ggagaacatt ctaagagcca gtcacagtgc tgtagatatc
     1201 accaaggtgg ctagaagaca tcgcatgtct ccttttcctc tgacgtctat ggacaaagcc
     1261 ttcattacag ttctggagat gactccggtg cttggtacag aaatcatcaa ttaccgagat
     1321 ggaatggggc gagtccttgc tcaagatgtg tatgcaaaag acaacctacc cccattccca
     1381 gcatcagtaa aagatggcta tgctgttcga gctgctgatg gtccaggaga tcgtttcatc
     1441 attggggaat cccaagctgg tgaacagcca actcagacag taatgcccgg acaagtgatg
     1501 cgggttacaa caggtgctcc aatcccctgc ggtgctgatg cagtagtgca agttgaagat
     1561 actgaactca tcagggaatc agatgatggt actgaagaac ttgaagtgcg aattctggtg
     1621 caagctcggc caggccaaga catcagaccc atcggccacg acattaaaag aggggagtgt
     1681 gttttggcaa aaggaaccca tatgggccct tcagaaattg gtctccttgc aactgtaggt
     1741 gtcacagaag ttgaagttaa taagtttcca gtggttgccg ttatgtcaac agggaatgag
     1801 ctactaaatc ctgaagatga cctcttacca ggaaagattc gggacagcaa tcgatcaaca
     1861 cttctagcaa caattcagga acatggttac ccaacaatca acttgggaat tgtaggagac
     1921 aacccagatg acttactcaa tgccttgaat gagggtatca gccgtgctga tgtcatcatc
     1981 acgtcaggag gtgtatccat gggggaaaag gactatctca agcaggtgct ggacatcgat
     2041 cttcatgctc agatccattt tggcagggtt tttatgaagc caggcttgcc aacaacattt
     2101 gcaactttgg atattgatgg tgtaagaaaa attatttttg cactaccagg gaatcctgta
     2161 tcagctgtgg tcacctgcaa cctctttgtt gtacccgcac tgagaaaaat gcagggtatc
     2221 ttggatcctc ggccaaccat catcaaagct aggttatcat gtgacgtaaa gctggaccct
     2281 cgcccagaat accaccggtg tatactgact tggcatcacc aagaaccact gccctgggcc
     2341 cagagtacag gtaatcagat gagcagccgt ctgatgagca tgcgcagtgc caatggattg
     2401 ctgatgctac ctccaaagac agagcagtat gtggaacttc acaaaggcga ggtggtggac
     2461 gtcatggtca tcggacggct atgatggtga ccaacaggag aaagtttcga tgcatgtcca
     2521 catatcattg actgtatcct gtcatatgca acggcacagc tagtttttct gatctggata
     2581 aaagttgatc tgtatagtca acatcttgaa ctatatttca aatgaattta aatacctttt
     2641 aaagaaaaaa cacacctaag aataaatctc aacagacaac tctattctgg ttatatcaaa
     2701 gcaaaatttt cctttcttgc aaattgcttt gtgtgttcaa tgctaggtct gatagcgata
     2761 gctttagtag acagcggtag gtgcctgcag aacttgtgtt tttctcatct ttaaatacaa
     2821 ctacttatgc tcttaatcaa ggctgtctgc ttctttatac tagtgtaggc aacacttgga
     2881 tttcccttct tagtatgctt cataactgct ttacagagag cttttgcttg ttctttctca
     2941 tgtatctcgt gtttatgtgc accatgccaa aagacgagtg actgcgcgga ggccccgctc
     3001 tgcctcaaga gccttccctg ctgagcaccc agggaagctc tcaccctcgc agcctctggc
     3061 acacacagta ctagcaggca gtaactggat accttttatt tgaacaaaca aacggggtgg
     3121 ggggaaatgc ttccttaagt gctgacagcc tttttaacca acacatttaa aattgtacag
     3181 aacaaaaata aaatcaaaga ctgatcttgt acagatatta gtgttaccag cattcatgtg
     3241 gaatcaagag caaaaataaa ataatgttaa acaactctgt accataacat tttctgtaat
     3301 gataatgaaa cttaatgaat aaaaaaaaat ccttgatcat tatttaaaaa aaaaaaaaaa
     3361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//