From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human histatin 3 (HIS2) gene exons 3-5, complete cds.
Date: 6 Nov 92 18:06:42 GMT
Distribution: bionet
Checksum: 32710 8

LOCUS       HUMHIS202    4447 bp ds-DNA             PRI       28-OCT-1992
DEFINITION  Human histatin 3 (HIS2) gene exons 3-5, complete cds.
ACCESSION   L05514
KEYWORDS    histatin 3; salivary protein.
SOURCE      Homo sapiens (individual_isolate individual L.S.) (library: lambda
            Charon 40) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4447)
  AUTHORS   Sabatini,L.M., Ota,T. and Azen,E.A.
  TITLE     Nucleotide sequence analysis of the human salivary protein genes
            HIS1 and HIS2 and the evolution of the STATH/HIS gene family
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    571..4447
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="HIS2"
     intron          order(L05513:423..461,1..570)
                     /number=2
                     /gene="HIS2"
     CDS             join(L05513:372..422,571..591,670..699,1758..1811)
                     /product="histatin 3"
                     /gene="HIS2"
                     /codon_start=1
     sig_peptide     join(L05513:372..422,571..576)
                     /gene="HIS2"
                     /codon_start=1
     mat_peptide     join(577..591,670..699,1758..1808)
                     /product="histatin 3"
                     /gene="HIS2"
                     /codon_start=1
     exon            571..591
                     /number=3
                     /gene="HIS2"
     intron          592..669
                     /number=3
                     /gene="HIS2"
     exon            670..699
                     /number=4
                     /gene="HIS2"
     intron          700..1757
                     /number=4
                     /gene="HIS2"
     exon            1758..1844
                     /number=5
                     /gene="HIS2"
     intron          1845..4447
                     /number=5
                     /gene="HIS2"
                     /partial
BASE COUNT     1572 a    710 c    752 g   1413 t
ORIGIN      
        1 tctttctatg aagttaatag aaaattggtc acaaaagaat actaatactt caacctatcc
       61 actaaattca aatgaatgtt tcaaaaacaa aattggttat ggcatcacag tttatcacat
      121 gattttatta tagaaggata gaagtagaaa aataaacata taagaagaac agagaaaagc
      181 acaatgcctg tctctatcag caaataaaat atttgtatgt tggtagcttt tgagctacat
      241 agaacatatt catataaaaa acaatccaat gtttcatttt tcagtttcca ctctcttatt
      301 caccaatgat agacttttct tgcctttcat aaaaaagata tataaaccaa aatgagttga
      361 tactttaata tagcatatta attatagaga agtttaccct tcactcattt taaagatgtc
      421 ataaagctaa aataactaat ttagcatgtc atcatccaaa gaatgcctcc attctattta
      481 atcataaatg tggctaagtc aatttttaca catattcttg aattatgaaa ttaagatatt
      541 aattattttc tcattttctt cttttccaag ggagctgatt cacatgcaaa ggtaagacat
      601 tttcatttac tggaaaactt gataattaat catatattga atttttaatc ttttcttttt
      661 atttcataga gacatcatgg gtataaaaga aaattccatg taagtgttct tctgataatg
      721 tgcactctga ataagttttc ttctctgact atttattctc ctagaataat tgatagttat
      781 ctctcaaata tatttatatc attaattgct aaagtgtaca ttgatttcat ttattcttgt
      841 tacagaggta aaaggtcaca aaaatcttgt gttctaacag catttcaacg gaaactcaat
      901 tacactctga ataagtcaat tttcaattat tctttgagag cttaagtatc tttctcttat
      961 aaataattac attgacctaa agaatagttc ctaattctat gaataattcc taattctatg
     1021 aagtataaca tatgcctaat gaagcataga ggctacccat gtaatgtggt ttctatctta
     1081 taatatttga ggatgataaa gtctttaaat taaacttact gtgctaaatt agacagaaaa
     1141 ttttatttaa catttttcta aatgtatgta taaaaatatc atattatttt gacctctaat
     1201 atcagtatga ataggggttc aaaagttctg cttactaata tagcaagtat atgtgttaaa
     1261 aagcactaag taaaatgatg cataaaaagg aatgaggact gtttgtgtta acagcagtgg
     1321 gtatgaaaga atgtaggagt tgttagagaa agtaagctca ttaaaagaat aagatgaaga
     1381 aacaccacct aagttggaaa cggtaacttt ctcctccccg ttatactcaa tgttgggcaa
     1441 aatagtaact tggaggtaat gttgttaaga agatttaaaa cctgtttgga gaggttgcct
     1501 ataatcagtg ttccaacatt tattattgcc acaaaaatat caacacacag taaatacttt
     1561 atcattttta cttgctttta aacatttttc tgaaagaaga aaaatgtaac taaaaatttg
     1621 aaaacattta tgtagataac acacgaggtc ataacaactt taacaatcta agctttcagt
     1681 gacagttttt gtgaagcatt tttactgtca ttgcctctat tctctgcaat ttgctctctc
     1741 cttttgtgtg tatgcaggaa aagcatcatt cacatcgagg ctatagatca aattatctgt
     1801 atgacaattg atatcttcag taatcacggg gcatgattat ggaggtaagc tgactctagt
     1861 tacttttctt tctagaagta tcaacactga cagttaaaac aaggaaaaat aaaaaaaaag
     1921 ccattaagcc aacaatcatt ccagtttaag aaatgtagcg tgggttagct ctttgaagtg
     1981 tgttgattta tatagatgct tctgactttg tagatatgtg gtgttatttc tgaggtctct
     2041 gttctgttcc attggtctat atgtctgttt tggtaccggt accatgctgt tttggtaacc
     2101 gtagccttgt agggtagttt gaagtcaagt agtgtgatgc cttcagcttt gttccttttg
     2161 cttacaattg tcttgtgtat atgagctctt ctgtagataa ttatgaaatt taagtactta
     2221 tttctaatcc tgtgaaaaat gtcaatggta gtttgatgag aatagcattg aatctataaa
     2281 ttactttggg cagtaaggcc attttcatga aattgattct tcttatccat gagaatggaa
     2341 tgtttttcca tttgtttgca tcttctctta tttccttgag cagtgatttt tggttctcct
     2401 tgaagaggtc cttcacatcc tttgttagtt gtatttctag gtattttatt atctttgttg
     2461 caattgtgaa tgggagttca ttcatgatgc aggtctctgc ttgctatctg atctacgaca
     2521 atcctgacaa aaacaagcaa tgggaaaagg atctcctagt caataaatgg tactgggaaa
     2581 actggctagc catatacaga aaactgaaac tggacccctt ccttacacct tatacaaaaa
     2641 ttaactcaag atggattgaa aattaaatga aaaacccaaa accaaaaaaa gaccctagaa
     2701 gaaaacctag gtgatatcat tcgggacata ggcatggaca aagacttcat gaagaaaatg
     2761 ccaaaagcaa tggcaacaaa agccaaaatt cacaaatggg atctaattaa actaaagagc
     2821 ttctgcacaa caaaagaaac tatcatcaga gtgaacaggt aacttagaga ttgggagaaa
     2881 atttttgcag tctacccatc tgacaaaggt gtagtgtcca gagtctacaa ggaacttaaa
     2941 caaatttaca agacaaaaac aaaaaacccg tctaaaagtg ggcaaaggat atgaacagac
     3001 acttctcaga agaagacatt tatgtggcca acaaacatga aaatagctca acatcacaat
     3061 cattagagaa atgcaaatca aaaccacagt aagataccat ctcacaccag ttagaattgt
     3121 gattactaaa aagtcaagaa acgatagatg atggctaggt tgtggagaga taggaacact
     3181 ttttcactgg tggtgagaat gcacattagt tcaaccattg tggaaaacta tggattcctc
     3241 aaggatctag aaccagaaat accatttgac ctagcaatcc tattactggg tatataccca
     3301 aaagaatata aagcattcta ctataaagac atatgcctag atatgtttat tgcagcacta
     3361 tttacaatag caaagacatg gaacaaccca aatgcccatc aatgatagac tggataaaga
     3421 aaatgtggta cgtatacacc atggaacact atgcggtcat taaaaggaat gagatcctgt
     3481 cctttgcagg gaaatggata aagctggaag ccatcatcct cagaaaacta aaacaggaac
     3541 agaaaaccaa acagcacatg cttcactcat aagtgggagc tgaacaatga gaacacatca
     3601 gggaggggaa caacacacac cagggatggg gggtaggagg tgacagaagg taacatagag
     3661 ggctgatcaa tagtgcagca aaccaccatg gcacatgtat acctatgaaa caatcctgca
     3721 cattctgcac atgtatccct gaacttaaat taaaataaat cataaaataa aataaaaatg
     3781 cctctgaggg aaagcttctg tttgctactg ttaagagaca gagttctggg tagggaaccc
     3841 ctgtgttttt atcctgaccc tgacaactag tttcatgacc ttaaagtatt cctaatcttc
     3901 tcttaacctt aattttataa gagacaaata catgttataa taatacttaa gctctttata
     3961 gaatttgtag ggctattgag agacattata gggaagccct tgttctggaa ggtgtatggt
     4021 tgtggccatg ggtttctctg ccactaaatc tgtacctggt tgttatttga agttttctgt
     4081 cctaaaatgt aatctttgga gaagctgcac aaccgccatc tgggaactca tgagaaattt
     4141 acgttttatg cctaagtaac tctaatgagc aatggctata ggaatgacta ataaaatatc
     4201 aacaaggaga tgggaatttt caaggaaata tgatatggta acaatgtcct ttttagaaag
     4261 tcatttttac ttatctatat tcacagcata aaatgttcca aaatctatga aatattaaat
     4321 attatacttc aaaataaagt aatattttgg agataaaaga gtactgttct acaattcaaa
     4381 attgaaatag ttcaaaagat ttcaaatatt tttaaatgta ttgggacatt ttattcatat
     4441 tgaattc
//