HDTenEightyP/NetNews huggingface dataset:
From: bhjelle@carina.unm.edu ()
Subject: Re: What homing device does a virus use?
Date: Wed, 18 Nov 92 23:59:41 GMT
Organization: University of New Mexico, Albuquerque

In article <1edkknINN7dp@im4u.cs.utexas.edu> turpin@cs.utexas.edu (Russell Turpin) writes:
>-*---
>
>But as I wrote originally, they clearly exhibit specificity in
>the tissue they infect, and it was this specificity that puzzled
>me when the tissues concerned seemed identical.  Does skin on the
>cheek by the mouth really have different cell receptors than skin
>on the cheek over by the ear?  And if not, how does the herpes
>virus "know" to infect one place and not the other? 
>
In general, tropism (ie, specificity) of viruses is determined
by cell-surface receptors that allow the virus to enter the
cell, and intracellular factors that permit its replication.
Some cells are permissive for viral replication, some non-
permissive, and some semi-permissive. Viruses can be tropic for
different tissues within an organism (eg, hepatitis B is
said to have "tropism" for liver), and can also exhibit
specficity for certain host species. Retroviruses, for example
can be specific for the host from which they were first isolated
(ecotropic), for other organisms (xenotropic), or for many
different organisms (amphotropic).

Little is known about what dictates the site specificity for
papillomaviruses, but it is likely that the same two factors
are in operation. Opportunity may be an important factor
but I doubt it. For example, no matter how much contact
there may be between non-genital skin and genital warts,
HPV strains that cause genital warts are not found in
warts outside of the genitals.

So the concept of ubiquitous viruses, that, like seeds,
"germinate" only where conditions are favorable is
probably correct for the papillomaviruses. Favorable
conditions occur on genital skin for some HPV types,
and for non-genital skin, or mucous membranes for others.
The favorable conditions will presumably someday be
defined in terms of cell-surface receptors and intracellular
factors.

Brian

Newsgroups: sci.med
From: andreaf@bonnie.Rational.COM (Andrea Frankel)
Subject: Re: Myofascial Pain-Dysfunction syndrome
Organization: Rational
Date: Wed, 18 Nov 1992 23:23:40 GMT

news@ramecs.UUCP (news) writes:

>1) What is Myofascial Pain-Dysfunction syndrome?

I believe that orthopedists use this diagnosis for the same cases that
rheumatologists call fibromyalgia.  (At least, that's true in some
cases!)

Since the "bible" of this field is Travell & Simons
_Myofascial_Pain_and_Dysfunction_ (aka "The Trigger Point Manual), I'll
make an educated guess that MPD Syndrome == lots of trigger points in
muscles, especially if there is no other cause that they can be traced
to.

>2) What does one do that causes one to get Myofascial Pain-Dysfunction syndrome?

If it's really fibromyalgia, then it is most likely a manifestation of
CFIDS.  My fibromyalgia is greatly reduced since getting some relief of
the CFIDS.

Trigger points (as opposed to fibromyalgia "tender points") are caused by
trauma to the muscle, such as overexertion to the point of pain, postural
problems, etc.

>2) How does one rid oneself of Myofascial Pain-Dysfunction syndrome?

a.  Trigger point therapy a la Travell and Simons (spray and stretch).

b.  Trigger point therapy a la sportsmassage (ischemic compression).  See 
Bonnie Pruden's books on "Pain Erasure" for a do-it-yourself procedure.

c.   Injection of cortisone and/or local anesthetics into trigger points.

And the question you didn't ask:

4. How does one prevent the trigger points from coming back, once they're 
under control?  

a.   slow careful stretching after preliminary warmup exercises and 
before any extreme exertion,

b.  regular deep massage (preferably sportsmassage rather than what is
usually called "deep tissue work"), and 

c.  regular use of moist heat whenever aching sets in.  A Thermaphore pad
is wonderful for this, especially if you are in a drought-stricken area
and can't take long hot showers!


Andrea Frankel (andreaf@rational.com) -- Rational, Grass Valley Office
"Wake now!  Discover that you are the song that the morning brings..."
From: klier@iscsvax.uni.edu
Newsgroups: sci.med
Subject: Re: Toothbrush sterilizers any good?
Date: 20 Nov 92 20:53:48 -0600
Organization: University of Northern Iowa

In article <curtisg.722196457@sco>, curtisg@sco.COM (Curtis Galloway) writes:
> I almost bought a toothbrush sterilizer the other day.  It has a UV bulb
> inside a case that holds your toothbrushes, and it claims to kill all kinds
> of bad germs that can, for example, re-infect you with a cold if you've had
> one recently.  Is this a waste of money, or are they on to something here?
> I'd gladly get it if it would make my colds go away one day sooner.

Personally, I'd save my money and buy new toothbrushes.  We used to gross
out students in beginning microbiology classes by having them culture 
their toothbrushes.  And the older the brush the better the fauna!

                                                     toothbrush!
If you're paranoid about germs, I suppose a 5 minute^ soak in 70%
ethyl alcohol (aka 140 proof booze) ought to do at least an adequate
job of sterilization without being particularly toxic.  Straight 3%
hydrogen peroxide might work too, but I've never been particularly 
impressed with weak H2O2.

Kay Klier  Biology Dept  UNI
Newsgroups: sci.med
Subject: Re: Deprenyl
From: geb@cs.pitt.edu (Gordon Banks)
Date: 18 Nov 92 21:26:24 GMT
Reply-To: geb@cs.pitt.edu (Gordon Banks)
Organization: Univ. of Pittsburgh Computer Science

In article <1992Nov16.235730.2369@cnsvax.uwec.edu> nyeda@cnsvax.uwec.edu (David Nye) writes:
>Deprenyl is an irreversible inhibitor of MAO-B purported to slow the
>progression of Parkinson's disease.  It as been in use in Europe for
>many years as an adjunct in the symptomatic treatment of PD.  The
>Europeans have, I am told, not been terribly excited about the drug.
>The studies that have purported to show slowing of the progression of
>the disease have methodological problems.  It is usually given twice
>a day.  A month's worth costs around $100.
>
>My question/suggestion:  since it irreversibly inhibits MAO-B and has
>a half life of well over a month, why not give only two tablets a
>month?  That is, presuming that one thinks it should be given at all
>if it's efficacy hasn't been proven conclusively.  It sure would be a
>heck of a lot cheaper.  Thoughts?
>

The studies suggesting efficacy used bid dosage, and that is likely
why that is what is recommended.  A similar situation was when
the first studies on ASA and TIAs came out, it was 2 tabs bid.
Since 1 tab "launders" the platelets practically permanently, one
wondered why such high and often doses were needed.  Recently
studies show that 1 baby aspirin per day is sufficient.  

I was recently in a market survey that would seem to indicate
that another MAO-B inhibitor is being considered for release.
The poop was that it didn't have the interactions with prozac
and demerol and didn't have amphetamine metabolites.



-- 
----------------------------------------------------------------------------
Gordon Banks  N3JXP      | "I have given you an argument; I am not obliged
geb@cadre.dsl.pitt.edu   |  to supply you with an understanding." -S.Johnson
----------------------------------------------------------------------------
From: markg@hpmwtd.sr.hp.com (Mark Goldsworthy)
Date: Fri, 20 Nov 1992 23:14:30 GMT
Subject: Re: Toothbrush sterilizers any good?
Organization: HP Santa Rosa Site (SRSD MWTD)
Newsgroups: sci.med

/ hpmwga:sci.med / mcovingt@aisun3.ai.uga.edu (Michael Covington) /  7:47 pm  Nov 19, 1992 /
>In article <curtisg.722196457@sco> curtisg@sco.COM (Curtis Galloway) writes:
>>I almost bought a toothbrush sterilizer the other day.  It has a UV bulb
>>inside a case that holds your toothbrushes, and it claims to kill all kinds
>>of bad germs that can, for example, re-infect you with a cold if you've had
>>one recently.  Is this a waste of money, or are they on to something here?
>>I'd gladly get it if it would make my colds go away one day sooner.
>
>Hmmm... if toothbrushes need sterilizing, why not dunk 'em in rubbing
>alcohol?  

I've heard that alcohol is not a particularly effective germicide. Your brush
would probably need to soak for a long time to kill the viruses and bacteria. I
guess this is why they use iodine solutions to prep people for surgery.

Mark Goldsworthy
Newsgroups: sci.med
From: amym@oakhill.sps.mot.com (Amy Moseley Rupp)
Subject: Retinal Tear Affecting Central Vision--Treatment?
Organization: Motorola Inc., Austin Tx.
Date: Thu, 19 Nov 1992 21:59:43 GMT

My mother has a retinal tear affecting her central vision.  It causes
her not to be able to read in that eye; although her peripheral vision
is still intact.  She's been told she has lattice degeneration of the
retina; I was told I had lattice degeneration about five years ago,
although I have no problems yet.

I am deeply concerned about her eyesight as she is only in her
early fifties with lots of life left before her; I have just had
a baby and would like her to be able to enjoy her grandchild and her
career as a librarian, which would be seriously hindered by a vision
loss.

Surgery is an option; but how successful is it?  Are there any preventative
things that can be done with lattice degeneration?  Does wearing contacts
exacerbate this problem?  I wear contacts and don't want to contribute
to my degeneration.  

Any advice or pointers to advice would be deeply appreciated by this
worried, exhausted new mom and her mother.  I feel like begging for
help!

I appreciated all the help I received from this group over my pregnancy;
see misc.kids for a birth announcement/story if interested.
-- 
Amy Moseley Rupp			Needed:  one witty, appropriate,
amym@oakhill.sps.mot.com		businesslike .sig that will perfectly
(512) 329-7117				reflect my philosophy of life and will
3 weeks and counting			fit in four lines or less.
From: turpin@cs.utexas.edu (Russell Turpin)
Newsgroups: sci.med
Subject: Re: Contact lenses provide better vision
Date: 15 Nov 1992 12:45:22 -0600
Organization: CS Dept, University of Texas at Austin
NNTP-Posting-Host: im4u.cs.utexas.edu

-*----
In article <1992Nov13.182426.911@kestrel.edu> king@reasoning.com (Dick King) writes:
>> In the rain, i was faced with the choice of doffing my glasses and having
>> 20/400 vision for the whole ride home, or keeping them on and having my 
>> vision deteriorate from 20/20 to perhaps 20/800 or worse on the way home 
>> as the glasses covered with water.

In article <28173@castle.ed.ac.uk> cam@castle.ed.ac.uk (Chris Malcolm) writes:
> Contact lenses are not the only solution here. ...

Undoubtedly all of the suggested gizmos work to some extent.  But
in the end, I agree with Dick King.  I wear glasses.  I used to
wear contacts.  In terms of quality of vision -- lesser distortion,
greater peripheral scope, etc. -- contacts win hands down,
*especially* in adverse conditions.  

Before my next ski trip, I may have to move back to contacts.
Last year, the only dim spot was having to struggle with special
goggles, defoggers, etc. when it snowed.  

Trust us: it's not misplaced vanity.

Russell
Newsgroups: sci.med
From: aristo@techunix.technion.ac.il (Noam Paz)
Subject: Info needed : Aucustic Neurinoma
Organization: Technion, Israel Inst. of Technology
Date: Mon, 16 Nov 1992 22:53:08 GMT

Dear readers of "sci.med",
I'm looking for information regarding 

	   Aucustic Neurinoma.
	   ------------------

Any on-line material, as well as hints and pointers to
sources of info would be greatly apreciated.

Since I can reach "sci.med" only indirectly, I'd thank you
if you could send me the material directly.

Many thanks in advance,

Noam Paz
Faculty of Computer Science,
Israel Institute of Technology,
Haifa 32000, Israel.

INTERNET :      aristo@techunix.technion.ac.il  
		aristo%techunix.BITNET@cunyvm.cuny.edu
BITNET   :      aristo@techunix
ARPANET  :      aristo%techunix.bitnet@cunyvm.cuny.edu
CSNET    :      aristo%techunix.bitnet@csnet-relay.csnet
UUCP     :      {ihnp4, allegra, rutgers}!psuvax1!techunix.bitnet!aristo
                ...uunet!techunix.BITNET!aristo
		uunet!techunix.technion.ac.il!aristo@uunet.UU.NET


Newsgroups: sci.med
From: mcovingt@aisun3.ai.uga.edu (Michael Covington)
Subject: Re: Toothbrush sterilizers any good?
Organization: AI Programs, University of Georgia, Athens
Date: Fri, 20 Nov 1992 03:47:51 GMT

In article <curtisg.722196457@sco> curtisg@sco.COM (Curtis Galloway) writes:
>I almost bought a toothbrush sterilizer the other day.  It has a UV bulb
>inside a case that holds your toothbrushes, and it claims to kill all kinds
>of bad germs that can, for example, re-infect you with a cold if you've had
>one recently.  Is this a waste of money, or are they on to something here?
>I'd gladly get it if it would make my colds go away one day sooner.

Hmmm... if toothbrushes need sterilizing, why not dunk 'em in rubbing
alcohol?  



-- 
:-  Michael A. Covington     internet mcovingt@uga.cc.uga.edu 
:-  Artificial Intelligence Programs       phone 706 542-0358
:-  The University of Georgia                fax 706 542-0349
:-  Athens, Georgia 30602-7415 U.S.A.     amateur radio N4TMI
From: ssammy@cs.strath.ac.uk (Paul Sammy 4th Year iE/CES)
Newsgroups: sci.med
Subject: Electrical Timing Properties of Myocardic cells
Date: 18 Nov 92 17:22:36 GMT
Distribution: sci
Organization: Information Engineering


Hello.

My final year project is to model the behaviour of a heart
using concurrent cellular automata techniques to simulate
the electrophysological properties of each type of
cell in a heart.

To this end I need to know the durations of each of the
four phases during a typical myocardic cell cycle.

These durations are different for each of the cells, and
I'd like to get some typical values.

I have skimmed vast numbers of Journals and books to get this
data but all don't seem to even give relative figures.

Would someone like to point me in the right direction?
I don't expect anyone to mail me typical values (unless
they *are* that easy to get hold of...) but Journal titles
or book titles would help.

Additionally, if this is completely the wrong newsgroup, please
tell me where to post!

Thanks,

Paul



--

 "Well spin my nipple nuts    | Internet: ssammy@cs.strath.ac.uk
  and send me to Alaska !"    | JANET   : ssammy@uk.ac.strath.cs
Copy this line into your .sig to protect against flames! [beta version .2]
From: cam@castle.ed.ac.uk (Chris Malcolm)
Newsgroups: sci.med
Subject: Re: Circumcisions (Are they ever performed on adults ?)
Date: 16 Nov 92 23:49:52 GMT
Organization: Edinburgh University

In article <1992Nov16.044856.1700@ennews.eas.asu.edu> prado@enuxhb.eas.asu.edu (Louis A. Prado) writes:

>Well considering that wives of uncircumcised men are much more likely to
>contract cancer of the cervix, 

I was under the impression that _one_ study had suggested that the
wives of uncircumsized men were _alightly_ more likely to get cancer;
a study whose results have not been replicated, and which has been
properly criticised for lack of control of other possibly causative
factors. In other words, I thought this now had the status of an urban
rumour. Anybody have the authoritative story?

>and all the other problems previously
>mentioned,

I must have missed these postings: what other problems? I don't
consider "it'll get dirty if you don't clean it" to be a problem.
That's the kind of argument dentists used to use for removing all
your teeth and fitting dentures.

-- 
Chris Malcolm    cam@uk.ac.ed.aifh          +44 (0)31 650 3085
Department of Artificial Intelligence,    Edinburgh University
5 Forrest Hill, Edinburgh, EH1 2QL, UK                DoD #205
Newsgroups: sci.med
From: aristo@techunix.technion.ac.il (Noam Paz)
Subject: Info needed : Gamma Knife
Organization: Technion, Israel Inst. of Technology
Date: Mon, 16 Nov 1992 22:51:04 GMT

Dear readers of "sci.med",
I'm looking for information regarding 

	   Gamma Knife.
	   ----------

Any on-line material, as well as hints and pointers to
sources of info would be greatly apreciated.

Since I can reach "sci.med" only indirectly, I'd thank you
if you could send me the material directly.

Many thanks in advance,

Noam Paz
Faculty of Computer Science,
Israel Institute of Technology,
Haifa 32000, Israel.

INTERNET :      aristo@techunix.technion.ac.il  
		aristo%techunix.BITNET@cunyvm.cuny.edu
BITNET   :      aristo@techunix
ARPANET  :      aristo%techunix.bitnet@cunyvm.cuny.edu
CSNET    :      aristo%techunix.bitnet@csnet-relay.csnet
UUCP     :      {ihnp4, allegra, rutgers}!psuvax1!techunix.bitnet!aristo
                ...uunet!techunix.BITNET!aristo
		uunet!techunix.technion.ac.il!aristo@uunet.UU.NET


Newsgroups: sci.med
From: c8922369@jupiter.newcastle.edu.au (Leon James Garde)
Subject: Re: Circumcisions as a Trivial Issue
Keywords: circsn
Organization: Uni of Newcastle, Australia
Date: Sat, 21 Nov 1992 09:07:26 GMT

turpin@cs.utexas.edu (Russell Turpin) writes:

>-*----
>In article <1992Nov20.142604.21021@lmpsbbs.comm.mot.com> markn@ssd.comm.mot.com (Mark Nowak) writes:
>> Ritualized mutilation is still mutilation even if it is socially
>> accepted. ...

>   mutilate, v.t., 1. to cut off or permanently destroy a
>   limb or essential part of: cripple  2: to cut or alter
>   radically so as to make imperfect  [Webster's New
>   Collegiate Dictionary]

>Lopping off the glans or testes or clitoris qualifies
>as mutilation. 

>Cutting a small piece of foreskin, piercing the ears (or 
>nose or ...), tattooing, etc., are not in the same category.
>Some people may find them objectionable, including some 
>people to whom they were done as infants.  But labeling it
>mutilation is hyperbole.  
mutilation : to alter .. to make imperfect. 
whats wrong with having a foresking ?
cant you use your imagination  and find somthing good about having a foreskin.

come on .. I'm sure we could make a 'top ten' list, and why shouldn't it be
taken seriously. you accept the female version can be wrong , in all forms.




>> ... And we think we're so superior to "savage" tribes living
>> in the jungles of third world countries.

>How quaint.  And how stupid.  In terms of ritualistic marking and
>similar behaviors, there are strong commonalities among people the
>world over. 

Oh, dear. isn't that a rstatement of the sentence above it ?

>Russell


leon
Newsgroups: sci.med
From: sue@netcom.com (Sue Miller)
Subject: Re: Mercury fillings and so on
Organization: Netcom - Online Communication Services (408 241-9760 guest)
Date: Fri, 20 Nov 1992 22:05:24 GMT


THIS PART IS NOT ABOUT MERCURY FILLINGS:

Gordon Banks writes:
> I  wrote:
>>
>>You're giving the impression that you don't read very well.  I
>>didn't specify anything.  I asked a favor, and it certainly
>>wasn't an unreasonable one.  
>>
>I suppose I thought it was an unreasonable one.  We have too much
>of this whining when the free information people give doesn't
>come in the form you want.  No one is entitled to any free
>information here.  If you don't like someone's post, then
>why not just skip it instead of flaming them?  I just thought
>it was rude to yell at Dave for "not answering the question",
>so, true to form, I was rude back.  Dave's too much a gentlemen
>to flame back.

It may have been true to form for your post to be "rude" back,
but I still reject your claim that I was rude and inflammatory
in the first place.  I challenge you to find any name-calling
or other rude flame-like behavior in my original posting.  
I do not like to flame people who are attempting to provide helpful 
information.  I only suggested that none of us attempt to read minds for free.

You are certainly entitled to feel that you are the sci.med cop
and decide whether or not I am not allowed to make such suggestions,
but I think you've been on usenet long enough now to realize that
your own posting behavior will set a better example than your beliefs 
about what should be posted here.  

I do like your "Dave's too much a gentleman to flame back."  
Perhaps he is, but then again, perhaps he wasn't offended and didn't 
feel a need to flame me in return.  Unless he says something, I
don't see why I need to believe that you speak for him.

>
>>
>>If you've got one of those versions of rn that require more lines
>>of followup than quoted text, you needn't send blank lines in order to
>>defeat it.  Hint:  the filter counts lines that begin with
>>">" characters.
>
>Hitting extra <CR>s is easier than globally replacing all the > with
>: or |.
>

Not if you have the right macro it isn't.  If you want it, let
me know.


NOW, BACK TO OUR REGULARLY SCHEDULED PROGRAMMING:

I used to have a mouthful of mercury amalgam fillings.  Over the last
few years almost all of them have been replaced with crowns,
inlays, onlays, etc.  They look beautiful.  I hate them.
They are so much more sensitive now, and I can't eat a lot of
crunchy foods any more.  If I'd known that I wouldn't have
let the dentist talk me into it.  The crowns were not an option
but the inlays/onlays were - and they cost a fortune.

Just a warning for all those people who have dentists trying
to talk them into a cosmetic upgrade when they have to replace
aging amalgam fillings.

Newsgroups: sci.med
From: kja@cbnewsf.cb.att.com (krista.j.anderson)
Subject: Re: What homing device does a virus use?
Organization: AT&T
Date: Thu, 19 Nov 1992 17:14:08 GMT

In article <17518@pitt.UUCP>, geb@cs.pitt.edu (Gordon Banks) writes:
> Just so the virus.  It either "bumps" into a cell that is "receptive"
> or it doesn't.  The virus has no intelligence.  It depends on
> physics to encounter a suitable host.  If it doesn't, it dies.

How does it die?  I mean, I know the immune system would kill it,
but is its lifespan otherwise limited?  For example, outside the
body, what happens to a virus?  Do airborn microorganisms
metabolize its protein coat or does it have any metabolic needs
without which it spontaneously decomposes or what? 
-- 
Krista Anderson
krista@ihlpf.att.com  or  ihlpf!krista@att.att.com  or  att!ihlpf!krista
---------------------------------------------------------------------------
From: rind@binoc.bih.harvard.edu (David Rind)
Newsgroups: sci.med
Subject: Re: Research project --->> HELP! <<---
Date: 15 Nov 92 21:47:18 GMT
Organization: Beth Israel Hospital, Harvard Medical School, Boston Mass., USA

In article <1992Nov15.115812.703@ab.wvnet.edu> schira@ab.wvnet.edu
 (John Schira, PA-C) writes:
>After a literature search I am unable to find any citations that detail 
>actual computer literacy rates among this group, or among docs in general.

I don't know if this is helpful to you, but there was a paper presented
at last week's SCAMC by Dr. Haynes from McMaster on rising computer
literacy rates among medical students.  The paper should be in the
Proceedings.
-- 
David Rind
rind@binoc.bih.harvard.edu
From: king@reasoning.com (Dick King)
Newsgroups: sci.med
Subject: Re: Contact lenses and blood vessels in the eye!?
Date: 16 Nov 92 18:35:53 GMT
Followup-To: rec.bicycles.tech
Organization: Reasoning Systems, Inc., Palo Alto, CA

In article <28173@castle.ed.ac.uk> cam@castle.ed.ac.uk (Chris Malcolm) writes:
>In article <1992Nov13.182426.911@kestrel.edu> king@reasoning.com (Dick King) writes:
>
>>In the rain, i was faced with the choice of doffing my glasses and having
>>20/400 vision for the whole ride home, or keeping them on and having my vision
>>deteriorate from 20/20 to perhaps 20/800 or worse on the way home as the
>>glasses covered with water.
>
>Contact lenses are not the only solution here.  [many unworkable "solutions"
>deleted for brevity]

Mr. Malcolm either has never cycled enough to perspire and this fog up the
inside of a helmet visor, or doesn't need corrective optics.

None of these "solutions" works.  RAIN-X on my glasses was an improvement over
bare glass, but only barely.  The droplets can hide a pretty big pothole
or car before they fall off, and they tend to leave behind a trail of even
tinier, more numerous, and more annoying droplets.

Note the Followup-To: rec.bicycles.tech line.

-dk
Newsgroups: sci.med.nutrition