From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for myocyte-specific enhancer factor 2 (XMEF2)
Date: 21 Dec 92 20:47:43 GMT
Distribution: bionet
Checksum: 24041 4

LOCUS       HUMXMEF2     1500 bp ss-RNA             PRI       18-NOV-1992
DEFINITION  H.sapiens mRNA for myocyte-specific enhancer factor 2 (XMEF2)
ACCESSION   X68502
KEYWORDS    DNA-binding protein; MADS box; alternative splicing;
            muscle specific protein; transcription factor; xmef2 gene.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Yu,Y.T., Breitbart,R.E., Smoot,L.B., Lee,Y., Mahdavi,V. and
            Nadal-Ginard,B.
  TITLE     Human myocyte-specific enhancer factor 2 comprises a group of
            tissue-restricted MADS box transcription factors.
  JOURNAL   Genes Dev. 6, 1783-1798 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=adult; *source: tissue=heart & skeletal muscle;
            *source: clone_library=lambda gt11+ZAP II;
               Related sequences:MEF2 and MEFa are isoforms of the same gene
            that also encodes the human SRF-related clones RSRFC4 and RSRFC9
            (acc# x63381).
               From EMBL    entry HSXMEF2;  dated 13-OCT-1992.
FEATURES             Location/Qualifiers
     misc_feature    <1..>1500
                     /note="linker sequence"
     5'UTR           2..249
     3'UTR           1348..1473
     polyA_signal    1444..1449
     CDS             250..1347
                     /gene="xmef2"
                     /product="myocyte-specific enhancerfactor 2 (XMEF2)"
                     /codon_start=1
                     /translation="MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIA
                     LIIFNSANRLFQYASTDMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEP
                     DEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEA
                     LPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGP
                     RGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPVGAEAWARRVPQPAAPPRRP
                     PQSASSLSASLRPPGAPATFLRPSPIPCSSPGPWQSLCGLGPPCAGCPWPTAGPGRRS
                     PGGTSPERSPGTARARGDPTSLQASSEKTQQ"
BASE COUNT      313 a    529 c    435 g    223 t
ORIGIN      
        1 cggagccgga gatgcagctc aaggggaaga aagcgccgtg aagaacctgg tggacagcag
       61 cgtctacttc cgcagcgtgg agggtctgct caaacaggcc atcagcatcc gggaccatat
      121 gaatgccagt gcccagggcc acagcccgga ggaaccaccc ccgccctcct cagcctgatc
      181 ctggaagaga ctcggggccc cccagcctcc gccaacccag acaaagatca ttccactcag
      241 cctgggacga tggggaggaa aaaaatccag atctcccgca tcctggacca aaggaatcgg
      301 caggtgacgt tcaccaagcg gaagttcggg ctgatgaaga aggcctatga gctgagcgtg
      361 ctctgtgact gtgagatagc cctcatcatc ttcaacagcg ccaaccgcct cttccagtat
      421 gccagcacgg acatggaccg tgtgctgctg aagtacacag agtacagcga gccccacgag
      481 agccgcacca acactgacat cctcgagacg ctgaagcgga ggggcattgg cctcgatggg
      541 ccagagctgg agccggatga agggcctgag gagccaggag agaagtttcg gaggctggca
      601 ggcgaagggg gtgatccggc cttgccccga ccccggctgt atcctgcagc tcctgctatg
      661 cccagcccag atgtggtata cggggcctta ccgccaccag gctgtgaccc cagtgggctt
      721 ggggaagcac tgcccgccca gagccgccca tctcccttcc gaccagcagc ccccaaagcc
      781 gggcccccag gcctggtgca ccctctcttc tcaccaagcc acctcaccag caagacacca
      841 cccccactgt acctgccgac ggaagggcgg aggtcagacc tgcctggtgg cctggctggg
      901 ccccgagggg gactaaacac ctccagaagc ctctacagtg gcctgcagaa cccctgctcc
      961 actgcaactc ccggaccccc actggggagc ttccccttcc tccccggagg ccccccagtg
     1021 ggggccgaag cctgggcgag gagggtcccc caacccgcgg cgcctccccg ccgacccccc
     1081 cagtcagcat caagtctgag cgcctctctc cggcccccgg gggccccggc gactttccta
     1141 agaccttccc ctatcccttg ctcctcgccc ggtccctggc agagcctctg cggcctgggc
     1201 ccgccctgcg ccggctgccc ttggccgacg gctggccccg gtaggagatc acccggtggc
     1261 accagcccag agcgctcgcc aggtacggcg agggcacgtg gggaccccac ctccctccag
     1321 gcctcttcag agaagaccca acagtgacgc ccccctccgc ggtgggggct tggaggtggg
     1381 cggctggact caatccaccc tggggggctc ctttccttct tcctatttgt gtgtatatcc
     1441 acaaataaaa cgcgcgtggc gtccgtggac cagaaaaaaa aaaaaaaaaa aaaaaaaaaa
//