From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.francisci germline DNA for immunoglobulin heavy chain (Vh,Dh1,
Date: 4 Sep 92 10:03:14 GMT
Distribution: bionet
Checksum: 50305     5

LOCUS       HEFGIGHA     2137 bp ds-DNA             VRT       04-SEP-1992
DEFINITION  H.francisci germline DNA for immunoglobulin heavy chain (Vh,Dh1,
            Dh2,Jh)
ACCESSION   Z11776
KEYWORDS    Ig D-segment; heavy chain; immunoglobulin; joining region;
            variable region.
SOURCE      Heterodontus francisci DNA.
  ORGANISM  Heterodontus francisci
            Eukaryota; Animalia; Chordata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Euselachii; Neoselachii; Galeomorphii;
            Heterodontiformes; Heterodontidae.
REFERENCE   1  (bases 1 to 2137)
  AUTHORS   Litman,G.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Hinds-Frey,K.R., Nishikata,H., Litman,R.T. and Litman,G.W.
  TITLE     Multiple somatic mechanisms are employed to generate immunoglobulin
            heavy chain diversity in a primitive vertebrate
  JOURNAL   J. Exp. Med. (1992) In press
  STANDARD  full staff_review
COMMENT
            From EMBL    entry HFGIGHA;  dated 06-AUG-1992.
FEATURES             Location/Qualifiers
     misc_feature    195..481
                     /function="Variable region"
                     /standard_name="Vh"
     misc_recomb     486..492
     misc_feature    899..915
                     /function="Diversity region"
                     /standard_name="Dh1"
     misc_feature    1296..1308
                     /function="diversity region"
                     /standard_name="Dh2"
     misc_feature    1690..1736
                     /function="joining region"
                     /standard_name="Jh"
BASE COUNT      612 a    413 c    446 g    666 t
ORIGIN
        1 gagctcagac tgaactatgg gacttgcccc gtgcctctgt gtgctgctgg cttgcttcac
       61 ctgtgagtat cctgaccggt ttagtcacac aacagaagtc tgcttcagat cttgtgtttt
      121 tatttctatt tattgatttg aatgttatct aatgtgatga tatttttttc attcaactga
      181 cagatgtccg gtccgatatt gtgctgaccc agtcattcgg tgacgaaaaa gcccggagaa
      241 tctcacaagc tttcctgctc cgtgagcgga ttcagtctgg acagctacta tgtgcactgg
      301 gttaagcaag ctccagggaa ggggctggag tggctccttg cttacagaaa accatcggat
      361 accatctatt acgcgcctgg agtccaaggt cgaatcattc cttccagagc ctcttccaca
      421 acctatattg agatcaaaag tctgagatcc gaagacaccg ccatgtatta ctgtgcaaga
      481 gacccactgc gacccaagca aatcctgggc tcgtacagaa acagagtgat aaaatttgca
      541 gcacatcccg tccaaagcta acggtcagta atggtatgat atacattgag atgtttttaa
      601 cttagactag aaggatgtat ttgatacagc aataaatagg ttaaaataaa attcacatta
      661 accaagctaa taaggataag gacccgcggg tactgcttgc agtgccagca ttggcgaaaa
      721 gggagtcaat gaaatcgttg atattctatc aatgggggcc aattttagtc caaatccgcc
      781 attctgagga aaaactcata gatggataat caaaatctgc aaaaccttct gttgactgag
      841 cgattttatt ctgacaatgg caatgaaaga gtatttgtgc gggttcgtgt cacagtgggt
      901 actacagtgg gtatcacagt gagacacacc gtgtcaaata ctgaggtgga ctattaactg
      961 taaaacacag agattaaatt ccacagagtt ctcagaaacc tgattccgac taccctaagt
     1021 gtgcatcagt gagacatttc agttcacact ggtcattata tgtgcaaagg agattgaaat
     1081 actcttaaaa gtatctgtcc agattttgca tgtcagtcaa cacttacaaa ccagaagaat
     1141 tttatacatt tttacaaatc tctaatactt ctagcaatta cttcaattta agactcattt
     1201 ccttcgaagt tcctgccgtg gtagagatcg taggtttgaa cacatccgct gtctggggtt
     1261 tttgtataag aaactcgctc tgtacagtac cgtgttatac tgggtggcac agcagttact
     1321 gtcaatacaa aaagtccctc tgcactaatt gattgaatct gggtccttgc tcgcttttac
     1381 aatccagctg tatatgcaat aaagtagcat ttgcttctag cacagtttaa tatggatgaa
     1441 ttatgataat tattaattca ccattgctga tttcgatagc atgttcatgg attacccgat
     1501 gcaatataaa acgtcaggat catttataaa cattgaaaaa taccattaac acacttatat
     1561 tttaatgaag atccatcgtg gctttacttt gcctctgatt tagcaacatt taaactaatg
     1621 ttggatttct ctctattctg tgcaaagccg gttattgtgt gacccagccc agggaatgta
     1681 acactgtgac atcatggact actggggaca agggaccatg gtgacggtga ctgcaggtaa
     1741 gaaacagctc attcagtaaa ggttttattt gtgtctttat tctatatttc tcttatttta
     1801 gccattcatt gattaactga aacgtgggtt cggttgattt tatattgaaa ttgtttgcaa
     1861 tgtttcattt gattgtggtg caaagggatt agagaataca gctgtttctc tacaaacgat
     1921 gctactgagg gattcagtgc ctgttttatg tgatttggtg tttatctgct gatgagtctg
     1981 tgtgcctgtg ttactttaaa taccgaaatg ttgttaagca gtttggcatt tccacattgt
     2041 tgaatctcgg tgatattttg ttgccacagc ttttctgaac gaatacaaac attaagtgct
     2101 aaaatatgtt tcaaatagga ttgtgggcag aaagctt
//