From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse granzyme D mRNA, complete cds.
Date: 29 Dec 92 21:38:25 GMT
Distribution: bionet
Checksum: 53352 3

LOCUS       MUSGRCD       940 bp ss-mRNA            ROD       15-DEC-1992
DEFINITION  Mouse granzyme D mRNA, complete cds.
ACCESSION   J03255
KEYWORDS    granzyme; serine esterase.
SOURCE      Mouse (strain C57 BL/6) CTL line B6.1, cDNA to mRNA, clone 11.15.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Jenne,D.E., Rey,C., Haefliger,J.-A., Qiao,B.-Y., Groscurth,P. and
            Tschopp,J.
  TITLE     Identification and sequencing of cDNA clones encoding the
            granule-associated serine proteases granzymes D, E and F of
            cytolytic T lymphocytes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 85, 4814-4818 (1988)
  STANDARD  full automatic
COMMENT     Draft entry and computer-readable sequence for [1] kindly provided
            by D.E.Jenne, 04-MAY-1988.
FEATURES             Location/Qualifiers
     sig_peptide     87..140
                     /codon_start=1
                     /note="granzyme D signal peptide"
     mat_peptide     147..842
                     /codon_start=1
                     /note="granzyme D"
     CDS             87..844
                     /partial
                     /note="granzyme D precursor"
                     /codon_start=1
                     /translation="MPPILILLTLLLPLRAGAEEIIGGHVVKPHSRPYMAFVMSVDIK
                     GNRIYCGGFLIQDDFVLTAAHCKNSSVQSSMTVTLGAHNITAKEETQQIIPVAKDIPH
                     PDYNATIFYSDIMLLKLESKAKRTKAVRPLKLPRSNARVKPGDVCSVAGWGSRSINDT
                     KASARLREVQLVIQEDEECKKRFRYYTETTEICAGDLKKIKTPFKGDSGGPLVCHNQA
                     YGLFAYAKNGTISSGIFTKVVHFLPWISWNMKLL"
BASE COUNT      253 a    249 c    231 g    207 t
ORIGIN      329 bp upstream of ApaI site.
        1 ggcccctgag cccacatctc cttcctcgcc ttccaagggc tttgtctgct ctgccctcct
       61 ccatcctgag cagccttcct gggaagatgc caccaatcct gattctcctg accctacttc
      121 tgcctctcag agctggagca gaggagatca tcggcggcca tgtggtgaag ccacactccc
      181 gcccctacat ggcattcgtt atgtctgtgg atattaaggg gaacaggata tactgtggag
      241 gcttcctgat tcaagatgac tttgtgctga cggctgctca ctgcaaaaac agctctgtcc
      301 aaagctcaat gacagtcaca ctgggggccc acaacatcac ggctaaggag gagacacagc
      361 agatcatccc tgtggcaaaa gacattcccc atccagatta taatgctact atcttctaca
      421 gtgacatcat gctgttaaag ctggagagta aggccaagag aactaaagct gtgagacccc
      481 tcaagttgcc cagatccaat gcccgggtga agccagggga tgtgtgcagt gtggctggct
      541 gggggtcaag gtccatcaat gacactaaag catctgcccg cctgcgagag gttcaactgg
      601 tcatccagga ggacgaggaa tgcaaaaaac gtttccgata ctacactgag accacagaga
      661 tttgtgctgg agacttgaag aaaataaaga ctcctttcaa gggtgactcg gggggacccc
      721 ttgtgtgtca caaccaagca tatggacttt tcgcctatgc aaaaaacgga acaatctctt
      781 caggaatctt cactaaggtt gtgcacttcc tgccgtggat aagctggaac atgaagttgc
      841 tctaacagga gttaaaccac ccgtgcctga ccagcctgtc cgacctcagg caagaaccat
      901 gtggagtggg cagcaaagaa tgaaaattca caataaataa
//