From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human type II cAMP-dependent protein kinase (Ht31) mRNA, complete
Date: 28 Jul 92 10:03:07 GMT
Distribution: bionet
Checksum: 41377     7

LOCUS       HUMHT31A     3045 bp ss-mRNA            PRI       28-JUL-1992
DEFINITION  Human type II cAMP-dependent protein kinase (Ht31) mRNA, complete
            cds.
ACCESSION   M90360
KEYWORDS    amphipathic helix binding domain; cAMP dependent; protein kinase;
            type II.
SOURCE      Homo sapiens thyroid gland cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3045)
  AUTHORS   Carr,D.W., Stofko-Hahn,R.E., Fraser,I.D., Bishop,S.M., Acott,T.S.,
            Brennan,R.G. and Scott,J.D.
  TITLE     Interaction of the regulatory subunit (RII) of cAMP-dependent
            protein kinase with RII-anchoring proteins occurs through an
            amphipathic helix binding motif
  JOURNAL   J. Biol. Chem. 266, 14188-14192 (1991)
  STANDARD  full staff_review
REFERENCE   2  (bases 1 to 3045)
  AUTHORS   Carr,D.W., Hausken,Z.E., Fraser,I.D., Stofko-Hahn,R.E. and
            Scott,J.D.
  TITLE     Association of the type II cAMP-dependent protein kinase with a
            human thyroid RII-anchoring protein: Cloning and characterization
            of the RII-binding domain
  JOURNAL   J. Biol. Chem. 267, 13376-13382 (1992)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     CDS             1..3045
                     /product="protein kinase"
                     /gene="Ht31"
                     /codon_start=1
                     /translation="NSLEVVSHPHPVVPKMEKELVPDQAVISDSTFSLANSPGSESVT
                     KDDALSFVPSQKEKGTATPELHTATDYRDGPDGNSNEPDTRPLEDRAVGLSTSSTAAE
                     LQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKATLALDSVLTEEGK
                     LLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQQFHEKSISAD
                     CAKDKALQLSNSPGASSAFLKAETEHNKEVAPQVSLLTQGGAAQSLVPPGASLATESR
                     QEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSACEVSGDV
                     TVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKAVTDPQ
                     GVGTPEMIPLDWEKGKLEGADHSCTMGDAEEAQIDDEAHPVLLQPVAKELPTDMELSA
                     HDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVIE
                     QVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEAT
                     GSLAGCFAGREEPEKIILPVQGPEPAAEMPDVKAEDEVDFRASSISEEVAVGSIAATL
                     KMKQGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKR
                     ESGSDSDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSL
                     SQILKPNRSRDRQSLDGFYSHGMGAEGRESESEPADPGDVEEEEMDSITEVPANCSVL
                     RSSMRSLSPFRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGG
                     AGVGNKPSSSLEVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICH
                     RSKQQGFNYCTSAISSPLTKSISLMTISHPGLDNSRPFHSTFHNTSANLTESITEENY
                     NFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKKSKEKKKK"
                     /citation=[1]
                     /citation=[2]
                     /partial
BASE COUNT      868 a    727 c    804 g    646 t
ORIGIN
        1 aattcccttg aggtggtttc acatccacat ccagttgtcc ctaaaatgga gaaagaactg
       61 gtgccagacc aggcagtaat atcagacagt actttctctc tggcaaacag tccaggcagt
      121 gaatcagtaa ccaaggatga cgcactttct tttgtcccct cccagaaaga aaagggaaca
      181 gcaactcctg aactacatac agctacagat tatagagatg gcccagatgg aaattcgaat
      241 gagcctgata cgcggccact agaagacagg gcagtaggcc tgtccacatc ctccactgct
      301 gcagagcttc agcacgggat ggggaatacc agtctcacag gacttggtgg agagcatgag
      361 ggtcccgccc ctccagcaat cccagaagct ctgaatatca aggggaacac tgactcttcc
      421 ctgcaaagtg tgggtaaggc cactttggct ttagattcag ttttgactga agaaggaaaa
      481 cttctggtgg tttcagaaag ctctgcagct caggaacaag ataaggataa agcggtgacc
      541 tgttcctcta ttaaggaaaa tgctctctct tcaggaactt tgcaggaaga gcagagaaca
      601 ccacctcctg gacaagatac tcaacaattt catgaaaaat caatctcagc tgactgtgcc
      661 aaggacaaag cacttcagct aagtaattca ccgggtgcat cctctgcctt tcttaaggca
      721 gaaactgaac ataacaagga agtggcccca caagtctcac tgctgactca aggtggggct
      781 gcccagagcc tggtgccacc aggagcaagt ctggccacag agtcaaggca ggaagccttg
      841 ggggcagagc acaacagctc cgctctgttg ccatgtctgt tgccagatgg gtctgatggg
      901 tccgatgctc ttaactgcag tcagccttct cctctggatg ttggagtgaa gaacactcaa
      961 tcccagggaa aaactagtgc ctgtgaggtg agtggagatg tgacggtgga tgttacaggg
     1021 gttaatgctc tacaaggtat ggctgagccc agaagagaga atatatcaca caacacccaa
     1081 gacatcctga ttccaaacgt cttgttgagc caagagaaga atgccgttct aggtttgcca
     1141 gtggctctac aggacaaagc tgtgactgac ccacagggag ttggaacccc agagatgata
     1201 cctcttgatt gggagaaagg gaagctggag ggagcagacc acagctgtac catgggtgac
     1261 gctgaggaag cccaaataga cgatgaagca catcctgtcc tactgcagcc tgttgccaag
     1321 gagctcccca cagacatgga gctctcagcc catgatgatg gggccccagc tggtgtgagg
     1381 gaagtcatgc gagccccgcc ttcaggcagg gaaaggagca ctccctctct accttgcatg
     1441 gtctctgccc aggacgcacc tctgcctaag ggggcagact tgatagagga ggctgccagc
     1501 cgtatagtgg atgctgtcat cgaacaagtc aaggccgctg gagcactgct tactgagggg
     1561 gaggcctgtc acatgtcact gtccagccct gagttgggtc ctctcactaa aggactagag
     1621 agtgctttta cagaaaaagt gagtactttc ccacctgggg agagcctacc aatgggcagt
     1681 actcctgagg aagccacggg gagccttgca ggatgttttg ctggaaggga ggagccagag
     1741 aagatcattt tacctgtcca ggggcctgag ccagcagcag aaatgccaga cgtgaaagct
     1801 gaagatgaag tggattttag agcaagttca atttctgaag aagtggctgt agggagcata
     1861 gctgctacac tgaagatgaa gcaaggccca atgacccagg cgataaaccg agaaaactgg
     1921 tgtacaatag agccatgccc tgatgcagca tctcttctgg cttccaagca gagcccagaa
     1981 tgtgagaact tcctggatgt tggactgggc agagagtgta cctcaaaaca aggtgtactt
     2041 aaaagagaat ctgggagtga ttctgacctc tttcactcac ccagtgatga catggacagc
     2101 atcatcttcc caaagccaga ggaagagcat ttggcctgtg atatcaccgg atccagttca
     2161 tccaccgatg acacggcttc actggaccga cattcttctc atggcagtga tgtgtctctc
     2221 tcccagattt taaagccaaa caggtcaaga gatcggcaaa gccttgatgg attctacagc
     2281 catgggatgg gagctgaggg tcgagaaagt gagagtgagc ctgctgaccc aggcgacgtg
     2341 gaggaggagg agatggacag tatcactgaa gtgcctgcaa actgctctgt cctaaggagc
     2401 tccatgcgct ctctttctcc cttccggagg cacagctggg ggcctgggaa aaatgcagcc
     2461 agcgatgcag aaatgaacca ccggagttca atgcgagttc ttggggatgt tgtcaggaga
     2521 cctcccattc ataggagaag tttcagtcta gaaggcttga caggaggagc tggtgtcgga
     2581 aacaagccat cctcatctct agaagtaagc tctgcaaatg ccgaagagct cagacaccca
     2641 ttcagtggtg aggaacgggt tgactctttg gtgtcacttt cagaagagga tctggagtca
     2701 gaccagagag aacataggat gtttgatcag cagatatgtc acagatctaa gcagcaggga
     2761 tttaattact gtacatcagc catttcctct ccattgacaa aatccatctc attaatgaca
     2821 atcagccatc ctggattgga caattcacgg cccttccaca gtaccttcca caataccagt
     2881 gctaatctga ctgagagtat aacagaagag aactataatt tcctgccaca tagcccctcc
     2941 aagaaagatt ctgaatggaa gagtggaaca aaagtcagtc gtacattcag ctacatcaag
     3001 aataaaatgt ctagcagcaa gaagagcaaa gaaaagaaaa aaaag
//