From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: ade2=adenylosuccinate synthetase [Schizosaccharomyces pombe,
Date: 27 Jan 93 05:58:42 GMT
Distribution: bionet
Checksum: 07498 5

LOCUS       S119047      1915 bp                    PLN       21-JAN-1993
DEFINITION  ade2=adenylosuccinate synthetase [Schizosaccharomyces pombe,
            Genomic/mRNA, 1915 nt]
ACCESSION   S49582 M98805
KEYWORDS    .
SOURCE      Schizosaccharomyces pombe
  ORGANISM  Schizosaccharomyces pombe
            Unclassified.
REFERENCE   1  (bases 1 to 1915)
  AUTHORS   Speiser,D.M., Ortiz,D.F., Kreppel,L., Scheel,G., McDonald,G. and
            Ow,D.W.
  TITLE     Purine biosynthetic genes are required for cadmium tolerance in
            Schizosaccharomyces pombe.
  JOURNAL   Mol. Cell. Biol. 12, 5301-5310 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 119047] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 3.  Map location: I.
FEATURES             Location/Qualifiers
     CDS             join(42..85,125..221,605..1768)
                     /note="Authors' translation does not match underlined
                     coding region in Fig. 3;
                     mismatches(100[E->V],106[Q->C],110[I->L]).  For the
                     protein sequence (NCBI gibbsq 119048):  Method: conceptual
                     translation supplied by author.  This sequence comes from
                     Fig. 4.
                     Author-given protein sequence is in conflict with the
                     conceptual translation"
                     /gene="ade2"
                     /product="adenylosuccinate synthetase"
                     /codon_start=1
                     /translation="MASVRETGVNVSNDGITVVLGSQWGDEGKGKLVDILCDNVDVCA
                     RCQGGNNAGHTIVANGVTYDFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELEKLEQK
                     GLKQRDRIFISDRAHLVFDYHQRADALNEAELGKQSIGTTGKGIGPAYSTKATRSGIR
                     VHHLYHWAEFEARYRKNVADLQKRYGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMY
                     EALQSKKRILVEGANALMLDLDFGTYPFVTSSNTTVGGVCTGLGVPPQRIANSIGVVK
                     AYTTRVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYT
                     SLNLTKLDILDALDEIKVAVAYIINGKRIETFPADLDSLEEAEIVYETFPGWKVPTTG
                     ITHWDQMPENAKKYIEFIEKFVGVPITFIGVGPGRDEMLVKE"
BASE COUNT      519 a    344 c    393 g    659 t
ORIGIN      
        1 atcaccaaaa cggagatcta ataaaaacat agaagaaaaa tatggcttca gtgcgagaaa
       61 ctggtgtaaa tgtttccaat gatgggtaag aaaattcttt gagaagaatt tactattcac
      121 acagaataac cgtcgtcctt ggcagtcaat ggggtgacga aggaaagggt aaacttgttg
      181 atatcctttg cgataatgtt gatgtctgtg ctcgctgtca ggtatgttac aaaagcttta
      241 tatagtggtg aaccgaacga ggtgatattg tgtaaaattt tttttcactc tactttgact
      301 cttaagtgcg ggacgtcgcg gaattactgc cgatgaaaaa taacattttt aataaaaaat
      361 ttaatttttt gtttaaatgt taatacaaat ctgctaaatg acttttccta cttggtacag
      421 tcaagaaaag tattttagag ctcactggat aagacgatct gcatcagtaa caaataaatt
      481 tataccaatt ctgaatggtt tcttcttttt gatttaatta tggaggttac ctttatgatc
      541 ttgccagctt ttttgtttgc ccttgtattg atttttcaaa tatatagcta acttttattt
      601 ttagggtggt aacaatgctg gtcataccat tgttgctaat ggtgtcactt acgattttca
      661 cattcttcct tcaggactcg taaatcctaa atgccagaac ttgattggtt ctggtgttgt
      721 cgtctattta cctgcttttt ttagtgagtt agagaaactt gtgcaaaagg gtttgaaatg
      781 tagagatcgt cttttcattt ctgatcgcgc tcatctagta tttgactacc atcaacgtgc
      841 agatgcttta aacgaggcag agctcggaaa acaaagcatc ggaacaaccg gaaagggtat
      901 tggtcctgct tattccacca aggctactcg cagcggtatt cgtgttcatc acttgtatca
      961 ttgggctgaa tttgaagctc gttaccgtaa gaacgttgct gacttgcaga aacgttatgg
     1021 tgctttcgag tatgatgttg aagctgaact cattcgttat aaggaattgg ctcaaagact
     1081 taagccattt gtcattgatg ctgttgcgtt catgtatgaa gctttacaaa gcaagaaacg
     1141 tatccttgtc gaaggtgcta acgctttgat gcttgatttg gactttggaa cttatccatt
     1201 cgttaccagc tctaacacta ctgttggtgg tgtttgcact ggtttgggtg ttcctcctca
     1261 gcgcattgct aactccatcg gtgtagtgaa agcttataca actcgtgtag gcgctggtcc
     1321 tttcccaacg gaacagctca acgaaattgg tgaccatctt caaagtgttg gaagagaagt
     1381 tggtgttacc accggtcgta aacgccgctg cggctggctt gatttggtcg ttgtcaaata
     1441 ctctactatg atcaatggtt acacttcttt gaaccttacc aagcttgaca ttttggatgc
     1501 cttggatgag atcaaagttg ctgttgccta cattattaac ggtaaacgca ttgaaacttt
     1561 tcctgctgat cttgattctc ttgaagaagc cgagattgta tacgaaactt tccctggttg
     1621 gaaagttcct acaacaggta tcactcattg ggatcagatg cctgagaatg ccaagaaata
     1681 catagagttc attgaaaagt ttgttggtgt tcccatcact ttcatcggtg ttggtcctgg
     1741 tcgtgatgag atgttggtta aggagtaagt tacgatttac aactagatat cctcaccatt
     1801 cttcactact ttctttatct aaattttgtt tattatacat cttattttag ctcttttcca
     1861 tttattttta tagtgctttt ctttttttcg aatagattca taaagcatat aactc
//