From: kstox@admips2.Berkeley.EDU (Ken Stox)
Subject: Re: DMSO as carrier?
Reply-To: kstox@admips2.Berkeley.EDU (Ken Stox)
Organization: AC Nielsen Co.
Date: Fri, 6 Nov 92 15:39:16 GMT

In article <1992Nov5.225105.20690@news2.cis.umn.edu>, donnell@manowar.micro.umn.edu (BogusMan) writes:
|> In article <UeyEIaG00WB6AWosBg@andrew.cmu.edu> Seth Malcolm Redmore <sr2s+@andrew.cmu.edu> writes:
|> >Hi there!
|> >
|> >DMSO will carry "stuff" through the skin with it, however
|> >its use in transderm patches is limited to those drugs which
|> >require < 10-15 mg per day.  (Yes, I'll get the reference on this,
|> >if anyone cares.)
|> >
|> >So, based on this, and based on what I have seen, it probably wouldn't
|> >be RealEffective in carrying, say, enough heroin through to stone ya.
|> >
|> >DMSO doesn't zip through the skin, leaving no sign of it's
|> >passage, its like smearing motor oil on your skin.  Sure, some penitrates,
|> >but it leaves a lot behind.
|> >
|> >A carrier like this would be perfect for soething like LSD, as
|> >the dosage is very low, however the convenience factor is low.
|> >
|> >DMSO has a very low vapor pressure and a very high boiling point,
|> >so it hangs around for _days_ if you spill it.  Weeks, even.
|> >(I was running a recrystallization in boiling (!) DMF/DMSO, got
|> >it  all over myself (the DMSO, that is, burned hell out of me))
|> >(Fortunatley, I hadn't added the DMF yet)
|> >
|> >So, this leads one to the conclusion that this would be a good way to
|> >dose someone against their will.  Something I am _way_ against.
|> >
|> >I dunno if this would work, you know, smear some LSD laced DMSO
|> >on a doorknob/steering wheel/vibrator, and let it sit for the unwary
|> >victim.  I have a suspicion that unless the trap was sprung within
|> >a few hours/a day, the LSD would oxidize to an inert form.
|> >
|> >Hmmmmm, as I sit here rambling, I wonder if it would be a more effective
|> >administration method to use DMSO as a carrier, instead of oral
|> >ingestion.
|> >
|> >Also, when taking it orally, wouldn't it be better to keep it under
|> >one's tongue? (the blotter or whatever...)
|> >
|> >Hmmmm...
|> >
|> >I have _no_ experience with acid (well, of the lysergic variety),
|> >shit, I've never even seen it.  So, take these ramblings with
|> >a grain of salt.
|> >
|> >--Seth
|> 
|> for the curious, avoid vetrinary or industrial DMSO, they contain lead
|> and other weird not-good-for-you things. 
|> LSD mixed with DMSO has been a popular semi-legend for
|> years. Abbie Hoffman talks about it in "Steal This Book". He calls it     
|> "Lace" and recommends carrying it in a water pistol when you go to 
|> demonstrations. Be interesting to see if anyone ever did...
|> Some fictional works have  used the idea, and have heads squirting cops
|> on the back of the neck with it, but can anyone come up with a real 
|> instance of this?
|> 
|> 					--Judex--
|> 

When the grateful dead played this year outside of Columbus Ohio, the headline
in the local papers the next days reported that the local sheriff had been
dosed in just such fashion during the show.

-- 
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Ken Stox 	Consultant to A.C. Nielsen	kstox@naitc.com

#include <std_disclaimer.h>
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Xref: sparky alt.drugs:18179 alt.folklore.urban:28128