From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human T-cell receptor germline gamma-chain pseudogene V-region (V6;
Date: 7 Jan 93 05:51:52 GMT
Distribution: bionet
Checksum: 14115 4

LOCUS       HUMTCGVA5     510 bp ds-DNA             PRI       06-JAN-1993
DEFINITION  Human T-cell receptor germline gamma-chain pseudogene V-region (V6;
            subgroup I).
ACCESSION   M13432
KEYWORDS    T-cell antigen receptor; T-cell receptor gamma-chain; germline;
            pseudogene; signal peptide; variable region.
SEGMENT     5 of 7
SOURCE      Human B-lymphoblastoid cell line SH DNA, clone lambda-SH7.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Lefranc,M.-P., Forster,A., Baer,R.J., Stinson,M.A. and
            Rabbitts,T.H.
  TITLE     Diversity and rearrangement of the human T cell rearranging gamma
            genes: Nine germ-line variable genes belonging to two subgroups
  JOURNAL   Cell 45, 237-246 (1986)
  STANDARD  full automatic
COMMENT     Printed copy of the sequence in [1] was kindly provided by
            M.-P.Lefranc, 01-AUG-1986.  Entry revisions for [1] also kindly
            provided by M.-P. Lefranc, 22-JUN-1988.  He adds, 'There is one
            base deletion between positions 481 and 482 in the sequence between
            the heptamer and the nonamer.' There is also a base deletion
            between positions 366 and 367, resulting in a frame-shift and a
            base change at 465, resulting in an in-frame termination codon in
            this pseudogene.
FEATURES             Location/Qualifiers
     CDS             join(1..43,163..472)
                     /pseudo
                     /gene="TCRGV6"
                     /codon_start=1
                     /note="putative"
     exon            1..43
                     /number=1
                     /gene="TCRGV6"
                     /note="V6 region"
     intron          44..162
                     /gene="TCRGV6"
                     /note="intron A"
     exon            163..472
                     /number=2
                     /gene="TCRGV6"
                     /note="V6 region"
     iDNA            (472.474)..>509
                     /gene="TCRGV6"
                     /note="V-J intervening DNA"
     misc_signal     473..479
                     /note="heptamer recombination signal; putative"
     misc_signal     502..510
                     /note="nonamer recombination signal; putative"
     misc_feature    1..509
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="TCRGV6"
BASE COUNT      136 a    115 c    118 g    141 t
ORIGIN      About 3 kb after segment 4; chromosome 7.
        1 atgtggtggg ccctagccct gcttctagct ttcctgtctc ttggtaagtg tgctgcctac
       61 agagaggctc acaggttggg ttttgttttg gatttttctt ctttagcaag ggacgccata
      121 ctaaggaata cctcattata ttttatgttg ttcccattgc agccagtcag atatctacta
      181 acttggaagc gaaaataaag tcaggcacca ggcagatggg gtcatctgct gtaatcacct
      241 gtgatcttcc tgtagaaaat gccttctaca tccactggta cctacgccag gaggggaagg
      301 ccccacagca tcttctgtac tatgacatct gcaactccag ggatatgttg gaatcaggag
      361 tcagtcagga aagcatgata cttatggaag tagaaggata agctggaaat ttatacctcc
      421 aaaactaaat gaaaatgcct ctggggtcta ttactgtgcc acctaggaca ggcagagtga
      481 tcagacctgc tctacaccac actgaatatc
//