From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse amyloid precursor-like protein mRNA, complete cds.
Date: 29 Dec 92 01:28:26 GMT
Distribution: bionet
Checksum: 03228 5

LOCUS       MUSAPLP      2359 bp ss-mRNA            ROD       08-DEC-1992
DEFINITION  Mouse amyloid precursor-like protein mRNA, complete cds.
ACCESSION   L04538
KEYWORDS    Alzheimer's disease; amyloid; amyloid beta precursor;
            amyloid precursor-like protein; transmembrane protein.
SOURCE      Mus musculus (library: Stratagene) brain cDNA to mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2359)
  AUTHORS   Wasco,W., Bupp,K., Magendantz,M., Gusella,J.F., Tanzi,R.E. and
            Solomon,F.
  TITLE     Identification of a mouse brain cDNA that encodes a protein related
            to the Alzheimer disease-associated amyloid beta protein precursor
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87, 10758-10762 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             88..2049
                     /standard_name="APLP"
                     /product="amyloid precursor-like protein"
                     /codon_start=1
                     /translation="MGPTSPAARGQGRRWRPPLPLLLPLSLLLLRAQLAVGNLAVGSP
                     SAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLLDPQRVLEYCRQMYPELH
                     IARVEQAAQAIPMERWCGGTRSGRCAHPHHEVVPFHCLPGEFVSEALLVPEGCRFLHQ
                     ERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPATPNPS
                     GMAAGDPSTRSWPLGGRAEGGEDEEEVESFPQPVDDYFVEPPQAEEEEEEEEERAPPP
                     SSHTPVMVSRVTPTPRPTDGVDVYFGMPGEIGEHEGFLRAKMDLEERRMRQINEVMRE
                     WAMADSQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRR
                     AALEGFLAALQGDPPQAERVLMALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRF
                     QVQTHLQVIEERMNQSLGLLDQNPHLAQELRPQIQELLLAEHLGPSELDASVPGSSSE
                     DKGSLQPPESKDDPPVTLPKGSTDQESSSSGREKLTPLEQYEQKVNASAPRGFPFHSS
                     DIQRDELAPSGTGVSREALSGLLIMGAGGGSLIVLSLLLLRKKKPYGTISHGVVEVDP
                     MLTLEEQQLRELQRHGYENPTYRFLEERP"
BASE COUNT      481 a    720 c    701 g    457 t
ORIGIN      
        1 cggcacgagg tggcgctggg agctcctgtc accgctgggg ccgggtaggg gcgggcggga
       61 gcgcagggac gtgagggccg agcggacatg gggcccacca gccccgccgc tcgcggtcag
      121 ggtcgccgct ggcgaccgcc gctgccgctg ttgctgccac tgtcattgct gcttctgcgc
      181 gcgcagctcg ccgtcgggaa cctggctgtt gggagcccca gcgcggccga ggctccgggg
      241 tcggctcaag tggctggact atgtgggcgt ctaacccttc accgggactt gcgcaccggc
      301 cgctgggaac cagacccaca gcgatcacga cgctgtcttc tggacccgca gcgcgtgctg
      361 gagtactgca gacagatgta ccccgagctg cacatagcac gcgtggagca ggctgcacag
      421 gccatcccga tggagcgctg gtgtgggggt acccggagtg gcagatgcgc ccacccccac
      481 catgaggttg tgcccttcca ttgcctgcct ggcgaattcg tgagtgaagc cctgctagtg
      541 cccgaaggct gtcggttctt gcaccaggag cgtatggacc agtgtgagag ttcaaccagg
      601 aggcatcagg aggctcagga ggcctgcagc tctcagggcc tcatcctgca cggctctggc
      661 atgcttttgc cctgtggctc tgatcggttc cgaggtgtgg agtatgtatg ctgtccacct
      721 cccgcaactc ccaacccatc tgggatggca gctggtgacc cctctacccg gtcctggccc
      781 ctggggggca gagcagaggg aggtgaggat gaagaggagg tggaatcttt ccctcagcca
      841 gtagacgatt acttcgtaga gccccctcag gctgaagaag aagaggaaga ggaggaagaa
      901 agggccccac ctcccagctc ccacacccct gtcatggtta gcagagtcac tcccacccca
      961 aggcctactg atggtgtgga tgtttacttt ggcatgcctg gggaaatcgg cgagcatgag
     1021 ggtttcctga gggccaagat ggacctggag gagcgtagga tgcgccagat taatgaggtg
     1081 atgcgtgaat gggccatggc tgacagccaa tctaagaacc tgccaaaggc ggacaggcag
     1141 gccctgaatg agcacttcca gtccattctg cagaccctgg aagaacaagt gtctggtgaa
     1201 cggcaacgcc tggtggagac ccacgccacc agagtcatcg ctctgatcaa cgaccagcgc
     1261 cgagcagccc tggaaggttt cctggcagcc ttacagggcg atccgcctca ggctgagcga
     1321 gttctgatgg ccctgaggcg ctacctgcgc gccgagcaga aagagcagag gcacactctg
     1381 aggcactacc agcacgtggc cgcagtggat cctgagaagg cccagcagat gcgctttcag
     1441 gtccagaccc accttcaggt gatcgaagag cgaatgaatc agagcctggg gctgctcgac
     1501 cagaaccctc acctggctca ggagctgcgg ccacagatcc aggagcttct ccttgctgaa
     1561 cacttgggtc ccagtgaact ggacgcctct gtgcccggga gcagcagtga ggacaaaggt
     1621 agcctccagc ctcccgaatc caaggacgat cccccagtga cccttccaaa agggtccaca
     1681 gatcaagagt catcctcctc tgggagagag aagctaactc cactggagca gtatgagcaa
     1741 aaggtgaatg catccgcccc gagggggttt ccgttccact cgtcagatat ccagcgggat
     1801 gaactggctc cttccgggac tggagtgtcc cgagaggcct tgtcaggtct gctgatcatg
     1861 ggagctggag gaggctctct cattgtccta tccttgctgc ttctgcgcaa gaagaaaccc
     1921 tatgggacta tcagccatgg agtggtggag gtggacccca tgctgaccct ggaggagcag
     1981 cagctccggg aacttcagag gcatggctat gagaacccca cctaccgctt cctggaagaa
     2041 cgaccttgac ccctacccta gctgccttca gctgagccct actgcccttc ttccggcccc
     2101 ccaaacccaa ctcccagctt ccggtggggg agggagatct tgacaaattc attcttgttt
     2161 ccccttccta gttccaaatt ccacaccctt agaaatcccc agctcctgtc ccacaaggga
     2221 cctcttcacc ttaatttatt ttacgttaat ttattgctcc ttaaggtgac ctgggtccca
     2281 ggtatgtatg tcactccctg gaattcacca tcccacgttt cttcactaac atcccaataa
     2341 actcctcttt ccctccggc
//