From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human immunoglobulin lambda light chain mRNA.
Date: 29 Jul 92 10:02:25 GMT
Distribution: bionet
Checksum: 08791     4

LOCUS       HUMIGLYM1     881 bp ss-mRNA            PRI       29-JUL-1992
DEFINITION  Human immunoglobulin lambda light chain mRNA.
ACCESSION   D01059
KEYWORDS    YM-1; immunoglobulin-lambda light chain.
SOURCE      Human bone marrow, B-cell, cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Tsunetsugu-Yokota,Y., Minekawa,T., Shigemoto,K., Shirasawa,T. and
            Takemori,T.
  TITLE     Characterization of a new subgroup of human Ig V-lambda cDNA clone
            and its expression
  JOURNAL   Mol. Immunol. (1992) In press
  STANDARD  full staff_review
COMMENT     Data kindly submitted in computer readable form by:
            Yasuko Tsunetsugu-Yokota
            National Institute of Health
            2-10-35, Kami-osaki
            Shinagawa-ku, Tokyo 141
            Japan
            Phone:  03-3444-2181
            Fax:    03-3446-6286
FEATURES             Location/Qualifiers
     CDS             23..745
                     /note="YM-1 gene product"
                     /codon_start=1
                     /translation="MAWTPLLLLFLSHCTGSLSQAVLTQPSSLSASPGTSASLTCTLR
                     SDINVGSPFIYWYQQKPGSPPQFLLRYKSDSDNQQGSGVPSRFSGSKDASANAGILLI
                     SGLQSEDEADYYCMIWRGTAVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATL
                     VCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRS
                     YSCQVTHEGSTVEKTVAPTERS"
     sig_peptide     23..79
                     /codon_start=1
     mat_peptide     146..193
                     /note="V region CDRI"
                     /codon_start=1
     mat_peptide     236..265
                     /note="V region CDRII"
                     /codon_start=1
     mat_peptide     368..388
                     /note="V region CDRIII"
                     /codon_start=1
     mat_peptide     389..427
                     /note="J region"
                     /codon_start=1
     mat_peptide     428..742
                     /note="C region"
                     /codon_start=1
BASE COUNT      195 a    290 c    213 g    183 t
ORIGIN
        1 ggaattccgg gttgtgtcca ccatggcctg gactcctctc ctcctcctgt tcctctctca
       61 ctgcacaggt tccctctcgc aggctgtgct gactcagccg tcttccctct ctgcatctcc
      121 tgggacatca gccagtctca cctgcacctt gcgcagtgac atcaatgtag gttccccctt
      181 catatactgg taccagcaga agccagggag tcctccccag tttctcctga ggtacaaatc
      241 agactcagat aaccaacagg gctctggagt ccccagccgc ttctctggat ccaaagacgc
      301 ttcggccaat gcagggattt tactcatctc tggcctccag tctgaggatg aggctgacta
      361 ttactgtatg atttggcgcg gcaccgctgt ggtatttggc ggagggacca agctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctgttc ccgccctcct ctgaggagct
      481 tcaagccaac aaggccacac tggtgtgtct cataagtgac ttctacccgg gagccgtgac
      541 agtggcctgg aaggcagata gcagccccgt caaggcggga gtggagacca ccacaccctc
      601 caaacaaagc aacaacaagt acgcggccag cagctacctg agcctgacgc ctgagcagtg
      661 gaagtcccac agaagctaca gctgccaggt cacgcatgaa gggagcaccg tggagaagac
      721 agtggcccct acagaacgtt cataggttct caaccctcac ccccaccacg ggagactaga
      781 gctgcaggat cccaggggag gggtctctcc tcccacccca aggcatcaag cccttctccc
      841 tgcactcaat aaaccctcaa taaatattct cattgtcaat c
//