From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: unc-5...unc-5=immunoglobulin and thrombospondin type 1
Date: 27 Jan 93 05:49:03 GMT
Distribution: bionet
Checksum: 02124 6

LOCUS       M255555S9     462 bp                    INV       12-JAN-1993
DEFINITION  unc-5...unc-5=immunoglobulin and thrombospondin type 1
            transmembrane protein {alternatively spliced} [Caenorhabditis
            elegans, variety Bergerans, Genomic/mRNA, 3 genes, 462 nt, segment
            9 of 9] 
ACCESSION   S47168
KEYWORDS    .
SEGMENT     9 of 9
SOURCE      Caenorhabditis elegans variety Bergerans
  ORGANISM  Caenorhabditis elegans
            Unclassified.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Leung-Hagesteijn,C., Spence,A.M., Stern,B.D., Zhou,Y., Su,M.W.,
            Hedgecock,E.M. and Culotti,J.G.
  TITLE     UNC-5, a transmembrane protein with immunoglobulin and
            thrombospondin type 1 domains, guides cell and pioneer axon
            migrations in C. elegans.
  JOURNAL   Cell 71, 289-299 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 116685] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 2.
FEATURES             Location/Qualifiers
     CDS             join(S47135:144..266,S47136:11..209,S47137:11..114,
                     S47164:11..185,S47165:11..377,S47166:11..699,
                     S47167:11..927,11..196)
                     /note="mismatch(614[V->L]).  immunoglobulin and
                     thrombospondin type 1 transmembrane protein;  For the
                     protein sequence (NCBI gibbsq 116688):  Method: conceptual
                     translation supplied by author.  This sequence comes from
                     Fig. 2.
                     Author-given protein sequence is in conflict with the
                     conceptual translation"
                     /gene="unc-5"
                     /product="UNC-5"
                     /codon_start=1
                     /translation="MDEITITTQPKSGYVIRNKPLRLQCRANHATKIRYKCSSKWIDD
                     SRIEKLIGTDSTSGVGYIDASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVA
                     TVHLAYMRKHFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDANVIR
                     ASDGSLIMSAARLSDSGNYTCEATNVANSRKTDPVEVQIYVDGGWSEWSPWIGTCHVD
                     CPLLRQHAHRIRDPHDVLPHQRRTRTCNNPAPLNDGEYCKGEEEMTRSCKVPCKLDGG
                     WSSWSDWSACSSSCHRYRTRACTVPPPMNGGQPCFGDDLMTQECPAQLCTADSSRIVI
                     SDTAVYGSVASIFIVASFILAILAMFCCKRGNSKKSKPLKPQKMNSEKAGGIYYSEPP
                     GVRRLLLEHQHGTLLGEKISSCSQYFEPPPLPHSTTLRSGKSAFSGYSSTRNAGSRAA
                     LIQECSSSSSGSGGKRTMLRTSSSNCSDDDNYATLYDYMEDKSVLGLDTSQNIVAAQI
                     DSNGARLSLSKSGARLIVPELAVEGEKMLYLAVSDTLTDQPHLKPIESALSPVIVIGQ
                     CDVSMSAHDNILRRPVVVSFRHCASTFPRDNWQFTLYADEGSGWQKAVTIGEENLNTN
                     MFVQFEQPGKKNDGFGWCHVMTYSLARLMLAGHPRRNSLSAAKRVHLAVFGPTEMSAY
                     RRPFELRVYCVPETGAAMESVWKQEDGSRLLCESNDFILNEKGNLCICIEDVIPGFSC
                     DGPEVVEISETQHRFVAQNGLHCSLKFRPKEINGSQFSTRVIVYQKASSTEPMVMEVS
                     NEPELYDATSEEREKGSVCVEFRLPFGVKDELARLLDMPNESHSDWRGLAKKLHYDRY
                     LQFFASFPDCSPTSLLLDLWEASSSGSARAVPDLLQTLRVMGRPDAVMVLERFLSAFP
                     QIVSP"
     CDS             join(S47134:1..82,S47135:142..266,S47136:11..209,
                     S47137:11..114,S47164:11..185,S47165:11..377,
                     S47166:11..699,S47167:11..927,11..196)
                     /note="mismatch(642[V->L]).  immunoglobulin and
                     thrombospondin type 1 transmembrane protein;  For the
                     protein sequence (NCBI gibbsq 118648):  Method: conceptual
                     translation supplied by author.  This sequence comes from
                     Fig. 2.
                     Author-given protein sequence is in conflict with the
                     conceptual translation"
                     /gene="unc-5"
                     /product="UNC-5"
                     /codon_start=1
                     /translation="MEDDTPDVSSDSNGDAAYSDYFLDYKSIMDEITITTQPKSGYVI
                     RNKPLRLQCRANHATKIRYKCSSKWIDDSRIEKLIGTDSTSGVGYIDASVDISRIDVD
                     TSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRVQEGTTLQLPC
                     QAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATNVANSR
                     KTDPVEVQIYVDGGWSEWSPWIGTCHVDCPLLRQHAHRIRDPHDVLPHQRRTRTCNNP
                     APLNDGEYCKGEEEMTRSCKVPCKLDGGWSSWSDWSACSSSCHRYRTRACTVPPPMNG
                     GQPCFGDDLMTQECPAQLCTADSSRIVISDTAVYGSVASIFIVASFILAILAMFCCKR
                     GNSKKSKPLKPQKMNSEKAGGIYYSEPPGVRRLLLEHQHGTLLGEKISSCSQYFEPPP
                     LPHSTTLRSGKSAFSGYSSTRNAGSRAALIQECSSSSSGSGGKRTMLRTSSSNCSDDD
                     NYATLYDYMEDKSVLGLDTSQNIVAAQIDSNGARLSLSKSGARLIVPELAVEGEKMLY
                     LAVSDTLTDQPHLKPIESALSPVIVIGQCDVSMSAHDNILRRPVVVSFRHCASTFPRD
                     NWQFTLYADEGSGWQKAVTIGEENLNTNMFVQFEQPGKKNDGFGWCHVMTYSLARLML
                     AGHPRRNSLSAAKRVHLAVFGPTEMSAYRRPFELRVYCVPETGAAMESVWKQEDGSRL
                     LCESNDFILNEKGNLCICIEDVIPGFSCDGPEVVEISETQHRFVAQNGLHCSLKFRPK
                     EINGSQFSTRVIVYQKASSTEPMVMEVSNEPELYDATSEEREKGSVCVEFRLPFGVKD
                     ELARLLDMPNESHSDWRGLAKKLHYDRYLQFFASFPDCSPTSLLLDLWEASSSGSARA
                     VPDLLQTLRVMGRPDAVMVLERFLSAFPQIVSP"
BASE COUNT       99 a    102 c     72 g    189 t
ORIGIN      
        1 tttatttcag ttcttcgcct cattccctga ttgctctccc acatcacttc tcctggatct
       61 ttgggaagct tcatcttctg gatcagctcg tgcagttcca gatcttcttc aaactcttcg
      121 tgtaatggga cgacccgatg cagtaatggt cctggaacga tttctatcag cttttccaca
      181 aattgtgtcc ccataagctc aattttttgc acaaacacaa ctagattcta cgtcgttttt
      241 ctatgggtat tctgttctgc gaacaatcac attttttctt cattttttgc tctttttgtc
      301 aatgaaaccg gtaatatatg cctgccccca atgcctccat gatttgtttt ttctatgaaa
      361 ctattttatt ttgtctgtaa ttaatatttc agtgtctttt gatgttgatt ctggtccatc
      421 ggtgtattat attcggtcta ataaatttga tttttgtcat ta
//