From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: P.troglodytes immunoglobulin alpha-1 constant region gene for
Date: 28 Jul 92 10:02:39 GMT
Distribution: bionet
Checksum: 10568     7

LOCUS       CHPIGA1CR    2717 bp ds-DNA             PRI       28-JUL-1992
DEFINITION  P.troglodytes immunoglobulin alpha-1 constant region gene for
            alpha-immunoglobulin heavy-chain constant region
ACCESSION   X53702
KEYWORDS    direct repeat; hinge region;
            immunoglobulin alpha-1 constant region gene;
            immunoglobulin-alpha heavy-chain constant (C) region.
SOURCE      Pan troglodytes DNA.
  ORGANISM  Pan troglodytes
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Pongidae.
REFERENCE   1  (bases 1 to 2717)
  AUTHORS   Kawamura,S., Tanabe,H., Watanabe,Y., Kurosaki,K., Saitou,N.,
            Omoto,K. and Ueda,S.
  JOURNAL   Mol. Biol. Evol. 8, 793-793 (1991)
  STANDARD  simple staff_entry
COMMENT     *source: cell_type=leucocyte; *source: clone_library=genomic;
            *source: clone=lambda L.P.Ig alpha.6; *source: is_germline=Y;
            Related sequence: X08041
            From EMBL    entry PTIGA1CR;  dated 07-APR-1992.
FEATURES             Location/Qualifiers
     5'UTR           <1..290
     mRNA            join(291..596,811..1170,1392..1786)
                     /gene="immunoglobulin alpha-1 constant region"
     CDS             join(291..596,811..1170,1392..1786)
                     /note="3' end"
                     /product="alpha-immunoglobulin heavy-chainconstant region"
                     /gene="immunoglobulin alpha-1 constant region"
                     /codon_start=3
                     /translation="SPTSPKVFPLSLDSNPQDGNVVVACLVQGFFPQEPLSVTWSESG
                     QGVTATNFPPSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQDVTVPCRG
                     PSTPCPPTPSTPPTPSPSCCHPRLLLHRPALEDLLLGSEANLTCTLTGLRDASGATFT
                     WSPSSGKSAVQGPPERDLCGCYSVSSVLPGCAEPWNHGETFTCTAAYPESKTPLTANI
                     TKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYL
                     TWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGK
                     PTHVNVSVVMAEVDGTCY"
                     /partial
     exon            291..596
                     /number=1
                     /note="CH1"
     intron          597..810
                     /number=1
     repeat_region   797..811
                     /rpt_type=direct
                     /note="hinge region"
     exon            811..1170
                     /number=2
                     /note="CH2"
     repeat_region   812..826
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   827..841
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   836..850
                     /rpt_type=direct
                     /note="hinge region"
     repeat_region   851..865
                     /rpt_type=direct
                     /note="hinge region"
     intron          1171..1391
                     /number=2
     exon            1392..1786
                     /number=3
                     /note="CH3"
     polyA_signal    1811..1816
BASE COUNT      522 a    926 c    811 g    458 t
ORIGIN
        1 gagctcaggg gactcagcca ctccatggca gagccctgtt taatataact tgtgtctggg
       61 atggcctggg tcagaggccc tatctaagga gcatgttcag aaaccgtgtc gctgggatga
      121 gacagctggg tccaaccgca ggcccatggt gcaggagctg tgtgaccttg gggctgtcac
      181 caggcctctc tgtactgggt tcctccagta tagaggagag gcaggcacag cctgtcctcc
      241 tggggacatg gcatgagggc cacgtcctca cagcgcattc tgtgttccag catccccgac
      301 cagccccaag gtcttcccgc tgagcctcga cagcaacccc caagatggga acgtggtcgt
      361 cgcctgcctg gtccagggct tcttccccca ggagccactc agtgtgacct ggagcgaaag
      421 cggacagggc gtgaccgcca caaacttccc gcccagccag gatgcctccg gggacctgta
      481 caccacgagc agccagctga ccctgccggc cacacagtgc ctagccggca agtccgtgac
      541 atgccacgtg aagcactaca cgaatcccag ccaggatgtg actgtgccct gccgaggtca
      601 gagggcaggc tggggagtgg ggcggggcca ccccgtcctg ccctgacact gcgcctgcac
      661 ccgtgttccc cacagggagc cgccccttca ctcacaccag agtggactgc gggccgagcc
      721 ccaggaggtg gtggtggaca ggccaggagg ggcaaggcgg gggcatgggg aagggcgttc
      781 tgaccagctc aggccatctc tccactccag gtccctcaac tccatgtccc ccaactccct
      841 caactccacc taccccatct ccctcctgct gccacccccg actgttgctg caccgaccgg
      901 cccttgagga cctgctctta ggttcagaag cgaacctcac gtgcacactg accggcctga
      961 gagatgcctc aggtgccacc ttcacctggt cgccctcaag tgggaagagc gctgttcaag
     1021 gaccacctga gcgtgacctc tgtggctgct acagcgtgtc cagtgtcctg cccggctgtg
     1081 ccgagccatg gaaccatggg gagaccttca cctgcactgc tgcctacccc gagtccaaga
     1141 ccccgctaac cgccaacatc acaaaatccg gtgggtccag accctgctcg gggctctgct
     1201 cagtgtcctg gtttgcaaag catattccca gcctgcctcc tccctcccaa tcctgggctc
     1261 cagtgctcat gccaagtaca gagggaaact gaggcaggct gagggccagg acacagcccg
     1321 gggtgcccac cagagcagag gggctctctc atcccctgcc cagccccctg acctggctct
     1381 ctaccctcca ggaaacacgt tccggcccga ggtccacctg ctgccgccgc cgtcggagga
     1441 gctggccctg aacgagctgg tgacgctgac gtgcctggca cgcggcttca gccccaagga
     1501 cgtgctggtt cgctggctgc aggggtcaca ggagctgccc cgcgagaagt acctgacttg
     1561 ggcatcccgg caggagccca gccagggcac caccaccttc gctgtgacca gcatactgcg
     1621 cgtggcagct gaggactgga agaaagggga caccttctcc tgcatggtgg gccacgaggc
     1681 cctgccgctg gccttcacac agaagaccat cgaccgcctg gcgggtaaac ccacccatgt
     1741 caatgtgtct gttgtcatgg cagaggtgga cggcacctgc tactgagcca cccgcctgtc
     1801 cccacccctg aataaactcc gtgctccccc aagcagcccc acgcttccat ccggcgcctg
     1861 tctgtccatc ctcagggtct cagcacttgg gaaagggcta gggaagaata ccccctgccc
     1921 tgagcctcgg ggggcccctg gcacctccat gagcctttcc accctggtgt gagtgtgagc
     1981 tgtgagtgtg agagtgtgtg gtgcaggagg cctcgctggt gtgagatctt aggtctgccg
     2041 aggcaggcac agcccagggt gggttctgag agacgcacat gccccggaga gttctgagtg
     2101 agcagtggca cggccgtttg tccctgagag agccgcctct ggctgcagct gggagggaat
     2161 agggagggta aaaggagcag gctagccaag acaggcgcag gtagtgggag gagcggcgag
     2221 ggagtgaggg gctggactcc agggccccac tgggaggaca agctccagga gggccccacc
     2281 accctagtgg gtgggcctca ggacgtccca ctgacgcatg caggaagggg cacctcccct
     2341 taaccacact gctctctacg gggcatgtgg gcacacttgc acactcacac tcacatatac
     2401 gcctgagccc tgcaggagcg gaacgttcac agcccagacc cagttccaga aaagccaggg
     2461 gagtcccctc ccaagccccc aagctcagcc tgctccccca ggcccctctg gcttccctgt
     2521 gtttccactg tgcacagctc aggcaccaac tccacagacc cctcccaggc agcccctgct
     2581 ccctgcctgg ccaagtctcc catcccttcc taagcccaac taggacacaa agcatagaca
     2641 gggaggggcc gcgtggggtg gcatcagaag caggccagtg agacagggcc tgcccagggc
     2701 cctctgcatg cctctgg
//