From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens CL 100 mRNA for protein tyrosine phosphatase
Date: 21 Dec 92 20:28:27 GMT
Distribution: bionet
Checksum: 17534 5

LOCUS       HUMCL100     2000 bp ss-RNA             PRI       18-NOV-1992
DEFINITION  H.sapiens CL 100 mRNA for protein tyrosine phosphatase
ACCESSION   X68277
KEYWORDS    tyrosine phosphatase.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2000)
  AUTHORS   Keyse,S.M. and Emslie,E.A.
  TITLE     Oxidative stress and heat shock induce a human gene encoding a
            protein-tyrosine phosphatase
  JOURNAL   Nature 359, 644-647 (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=foreskin; *source: cell_type=fibroblast; *source:
            cell_line=EK 4; *source: clone_library=cDNA/ Lambda gt10; *source:
            clone=CL 100;
               From EMBL    entry HSCL100;  dated 23-OCT-1992.
FEATURES             Location/Qualifiers
     misc_signal     1441..1449
                     /function="mRNA destabilizing signal"
                     /note="CL100"
     polyA_signal    1978..1983
     CDS             234..1337
                     /EC_number="3.1.3.48"
                     /gene="CL 100"
                     /product="protein-tyrosine phosphatase"
                     /codon_start=1
                     /translation="MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSV
                     NVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTL
                     ALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESG
                     CSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHY
                     QYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRT
                     NRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTS
                     TTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC"
BASE COUNT      414 a    566 c    539 g    481 t
ORIGIN      
        1 tttgggctgt gtgtgcgacg cgggtcggag gggcagtcgg gggaaccgcg aagaagccga
       61 ggagcccgga gccccgcgtg acgctcctct ctcagtccaa aagcggcttt tggttcggcg
      121 cagagagacc cgggggtcta gcttttcctc gaaaagcgcc gccctgccct tggccccgag
      181 aacagacaaa gagcaccgca gggccgatca cgctgggggc gctgaggccg gccatggtca
      241 tggaagtggg caccctggac gctggaggcc tgcgggcgct gctgggggag cgagcggcgc
      301 aatgcctgct gctggactgc cgctccttct tcgctttcaa cgccggccac atcgccggct
      361 ctgtcaacgt gcgcttcagc accatcgtgc ggcgccgggc caagggcgcc atgggcctgg
      421 agcacatcgt gcccaacgcc gagctccgcg gccgcctgct ggccggcgcc taccacgccg
      481 tggtgttgct ggacgagcgc agcgccgccc tggacggcgc caagcgcgac ggcaccctgg
      541 ccctggcggc cggcgcgctc tgccgcgagg cgcgcgccgc gcaagtcttc ttcctcaaag
      601 gaggatacga agcgttttcg gcttcctgcc cggagctgtg cagcaaacag tcgaccccca
      661 tggggctcag ccttcccctg agtactagcg tccctgacag cgcggaatct gggtgcagtt
      721 cctgcagtac cccactctac gatcagggtg gcccggtgga aatcctgccc tttctgtacc
      781 tgggcagtgc gtatcacgct tcccgcaagg acatgctgga tgccttgggc ataactgcct
      841 tgatcaacgt ctcagccaat tgtcccaacc attttgaggg tcactaccag tacaagagca
      901 tccctgtgga ggacaaccac aaggcagaca tcagctcctg gttcaacgag gccattgact
      961 tcatagactc catcaagaat gctggaggaa gggtgtttgt ccactgccag gcaggcattt
     1021 cccggtcagc caccatctgc cttgcttacc ttatgaggac taatcgagtc aagctggacg
     1081 aggcctttga gtttgtgaag cagaggcgaa gcatcatctc tcccaacttc agcttcatgg
     1141 gccagctgct gcagtttgag tcccaggtgc tggctccgca ctgttcggca gaggctggga
     1201 gccccgccat ggctgtgctc gaccgaggca cctccaccac caccgtgttc aacttccccg
     1261 tctccatccc tgtccactcc acgaacagtg cgctgagcta ccttcagagc cccattacga
     1321 cctctcccag ctgctgaaag gccacgggag gtgaggctct tcacatccca ttgggactcc
     1381 atgctccttg agaggagaaa tgcaataact ctgggagggg ctcgagaggg ctggtcctta
     1441 tttatttaac ttcacccgag ttcctctggg tttctaagca gttatggtga tgacttagcg
     1501 tcaagacatt tgctgaactc agcacattcg ggaccaatat atagtgggta catcaagtcc
     1561 atctgacaaa atggggcaga agagaaagga ctcagtgtgt gatccggttt ctttttgctc
     1621 gcccctgttt tttgtagaat ctcttcatgc ttgacatacc taccagtatt attcccgacg
     1681 acacatatac atatgagaat ataccttatt tatttttgtg taggtgtctg ccttcacaaa
     1741 tgtcattgtc tactcctaga agaaccaaat acctcaattt ttgtttttga gtactgtact
     1801 atcctgtaaa tatatcttaa gcaggtttgt tttcagcact gatggaaaat accagtgttg
     1861 ggtttttttt tagttgccaa cagttgtatg tttgctgatt atttatgacc tgaaataata
     1921 tatttcttct tctaagaaga cattttgtta cataaggatg acttttttat acaatggaat
     1981 aaattatggc atttctattg
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