From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Neurospora crassa cAMP-dependent protein kinase (cot-1) gene,
Date: 11 Sep 92 10:05:24 GMT
Distribution: bionet
Checksum: 01585     7

LOCUS       NEUCOTPK     3376 bp ds-DNA             PLN       11-SEP-1992
DEFINITION  Neurospora crassa cAMP-dependent protein kinase (cot-1) gene,
            complete cds.
ACCESSION   M83093
KEYWORDS    cAMP-dependent protein kinase.
SOURCE      Neurospora crassa (strain 74-OR23-1A) (library: Orbach/Sachs
            cosmid) DNA.
  ORGANISM  Neurospora crassa
            Eukaryota; Fungi; Eumycota; Ascomycotina; Pyrenomycetes;
            Sordariales; Sordariaceae.
REFERENCE   1  (bases 1 to 3376)
  AUTHORS   Yarden,O., Plamann,M., Ebbole,D.J. and Yanofsky,C.
  TITLE     cot-1, a gene required for hyphal elongation in Neurospora crassa,
            encodes a protein kinase
  JOURNAL   EMBO J. 11, 2159-2166 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             join(1093..1280,1359..2243,2303..2779,2838..3150)
                     /product="protein kinase"
                     /gene="cot-1"
                     /codon_start=1
                     /translation="MDNTNRPHLNLGTNDTRMAPNDRTYPTTPSTFPQPVFPGQQAGG
                     SQQYNQAYAQSGNYYQQNHNDPNTGLAHQFAHQNIGSAGRASPYGSRGPSPAQRPRTS
                     GNSGQQQTYGNYLSAPMPSNTQTEFAPLPSGTPTNMAPMPTTTRRSAHSWPLTSLRTA
                     SSAPGSATRGECCSDALLPLHPAVIGADTLFRQSEMEQKLGETNDARRRESIWSTAGR
                     KEGQYLRFLRTKDKPENYQTIKIIGKGAFGEVKLVQKKADGKVYAMKSLIKTEMFKKD
                     QLAHVRAERDILAESDSPWVVKLYTTFQDANFLYMLMEFLPGGDLMTMLIKYEIFSED
                     ITRFYIAEIVLAIDAVHKLGFIHRDIKPDNILLDRGGHVKLTDFGLSTGFHKLHDNNY
                     YTQLLQGKSNKPRDNRNSVAIDQINLTVSNRAQINDWRRSRRLMAYSTVGTPDYIAPE
                     IFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDDITLG
                     VDAENLIRSLICNTENRLGRGGAHEIKSHAFFRGVEFDSLRRIRAPFEPRLTSAIDTT
                     YFPTDEIDQTDNATLLKAQQAARGAAAPAQQEESPELSLPFIGYTFKRFDNNFR"
     exon            1093..1280
                     /number=1
                     /gene="cot-1"
                     /partial
     intron          1281..1358
                     /number=1
                     /gene="cot-1"
     exon            1359..2243
                     /number=2
                     /gene="cot-1"
     intron          2244..2302
                     /number=2
                     /gene="cot-1"
     exon            2303..2779
                     /number=3
                     /gene="cot-1"
     intron          2780..2837
                     /number=3
                     /gene="cot-1"
     exon            2838..3150
                     /number=4
                     /gene="cot-1"
                     /partial
BASE COUNT      747 a   1040 c    815 g    774 t
ORIGIN      Chromosome IVR
        1 cccgggagtg cccgctccca gccagtaaca aattcccgga ccagagtctc gatgctctcg
       61 aggtccaatg ccgttgcgtc gagcttcaac actcggggga ctggtggttt acctatagtg
      121 tgcttgtgag gcacgagaag atggcagcag tgcggaacag acagcaacga gttgacgtct
      181 gacgatgagg ttggagtcag gggttttcag gttgaccagg gcaccccata gttaggtggt
      241 cctgtttcgg cctggagctc accactggac ctgggcatgt catcccaaac atggaacccc
      301 tctttctacg acctccttat tcctgggcat cgtgtactag attcacatcg aggccagctt
      361 cctgtggcaa cagaaaacgg aaacgtaaag tccattgttg tctgttgtta ttcaaggtgt
      421 cctttgaatg cgcccgtggc tgtctcatat catcacagtc tatgtcttgg tcacttatag
      481 atgggatctg ttaggttcca tgtcacctct atacgtctag gtctttcctt ttatactgat
      541 accgcacggc accctgcgcc cacctgcctt tggcctttgc gttgctgatt cgtgcgccta
      601 ggttctcgaa ttacagaggc cctgaatcgc ctccagccag tgctctcctg tcagactcct
      661 tcctgtaggt aggctggaga ggctcacgtc ggtcacgctt ccactttgct tccacttcca
      721 cactgcgcct atcgactgca cgttccagcg ggacacttcc acttcggacg gtgccactca
      781 accacctgcc cccccagcct ggccgccctc gattcccatc cctaccatct acagtagcca
      841 accgtcgttc gatcctcgtt ggaccctggt cccaagaaaa agcaacctcc tttcctcccg
      901 tctccccata cctatcccgt cttgtacaca aacccctttc tgtgcgcata gatcccatcg
      961 atcggtctgg gagctcgact ctgatcgttt ctccatctgc cgtccctcgg aatctcgtct
     1021 gagctcgctt gcgcccttcc cgctacatac acccggaatc cactgtttac cgtttagaga
     1081 caaggtacca agatggacaa caccaaccgc ccccatctca acctgggcac caacgatacc
     1141 cgcatggctc caaacgatcg tacctatccc accaccccgt ccaccttccc ccaacccgtc
     1201 ttcccaggtc aacaagccgg tggttcccag cagtacaacc aggcctacgc ccagtccggc
     1261 aactactatc aacagaacca gtatgccagc cactacgccc ctcctggtgc cgccgactac
     1321 ggcttcgttc aagctcattc taacattgac ggtactagca acgaccccaa cactggtctc
     1381 gcccaccagt tcgcccatca gaacattggc agcgccggaa gagcctctcc ctacggttct
     1441 cgtggcccat ctcccgctca acgccctcgc acatccggaa actctggcca gcagcaaacc
     1501 tacggcaact atctgagcgc cccgatgcct tcgaataccc agaccgagtt cgctccgctc
     1561 ccgagcggaa ccccgacaaa tatggcccca atgccaacaa caaccagaag aagtgctcac
     1621 agctggcctc tgacttcttt aaggacagcg tcaagcgcgc cagggagcgc aaccagaggt
     1681 gaatgctgca gcgatgcgct tttgccccta catcccgccg tgatcggtgc tgacaccctt
     1741 ttcagacaga gcgagatgga gcagaagctc ggtgagacca acgatgcccg ccgtcgcgaa
     1801 tcgatctggt caaccgctgg ccggaaggag ggccagtatt tgcgcttcct gagaaccaag
     1861 gacaagcccg agaactacca gaccatcaag atcatcggca agggcgcttt cggcgaggtc
     1921 aagctcgtgc agaagaaggc cgacggcaag gtttacgcca tgaagtcgct tatcaagacg
     1981 gaaatgttca agaaggacca gcttgcccac gtccgagcag aaagagatat cttggccgag
     2041 tcggacagcc catgggttgt caagctctac accaccttcc aggatgcgaa cttcctttac
     2101 atgctcatgg agttcttgcc cggtggtgac ttgatgacca tgctgatcaa atacgaaatc
     2161 ttctcggagg atattacccg tttctacatt gccgaaatcg tcttggctat cgacgcggtc
     2221 cataagctgg gcttcattca caggtaagct tcgccggaag caatgctctg gaaaagagat
     2281 actgacacgg ttgtgcatgc agagatatta agccagacaa catccttctt gataggggtg
     2341 gtcatgtcaa gcttacagat ttcggtctct ctaccggctt ccacaagctc catgataaca
     2401 actactacac acaactgctc cagggcaaat ccaacaagcc gcgcgacaac cgcaactcgg
     2461 ttgctattga ccaaatcaac ctgacggtca gcaaccgtgc acagatcaat gactggagac
     2521 gctccagacg tttgatggcc tactcgaccg tcggtacacc agattatatt gctccggaaa
     2581 tcttcactgg ccatggttac tcgtttgatt gcgattggtg gtctttgggt accatcatgt
     2641 tcgagtgctt ggtcggctgg cctcctttct gcgccgagga tagccacgac acttaccgca
     2701 agatcgtgaa ctggaggcac tcgctttact tcccggatga catcaccctt ggtgtagatg
     2761 ccgagaacct tatcagaagg tatgcatgct tttgacttcc cccaaaatca cgcgctcacc
     2821 atattgactt gtcatagcct catctgcaac actgagaacc gtctcggccg tggtggtgct
     2881 cacgaaatca agagccacgc cttcttccgc ggcgttgagt tcgacagctt gcgtcgcatc
     2941 cgtgcgccct tcgagccccg tcttacatcc gccatcgata ccacatactt ccctacggac
     3001 gagattgacc agacggataa cgccacgctg ctcaaggctc agcaggccgc taggggcgcc
     3061 gctgcccctg cgcagcagga ggagagccca gaactcagct tgcctttcat tggatacacg
     3121 ttcaagcgtt tcgacaacaa cttccgataa ttgcgttacg tcttctcgct gtctgaataa
     3181 tgagcgttgg ttttcttggg ggggaggaag ggggcgtaat agtgatggcg aaagggagaa
     3241 gaggttgtgc tgcggggcgg cagtatctgg gtacccctta tacttggctt tgacgtcttt
     3301 gctagctcgc ggtgctgttg aaatttctga tggcagagac actttgctga tagtacgcga
     3361 attttccgtt ccgctc
//