From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens centromere autoantigen C (CENPC) mRNA, complete cds.
Date: 24 Jul 92 10:06:32 GMT
Distribution: bionet
Checksum: 08283     7

LOCUS       HUMCENPRO    3132 bp ss-mRNA            PRI       24-JUL-1992
DEFINITION  H.sapiens centromere autoantigen C (CENPC) mRNA, complete cds.
ACCESSION   M95724
KEYWORDS    centromere; centromere autoantigen C; inner kinetochore plate;
            scleroderma autoantigen.
SOURCE      Homo sapiens cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3132)
  AUTHORS   Saitoh,H., Tomkiel,J., Cooke,C.A., Ratrie,H., Maurer,M.,
            Rothfield,N.F. and Earnshaw,W.C.
  TITLE     CENP-C, an autoantigen in scleroderma, is a component of the human
            inner kinetochore plate
  JOURNAL   Cell 70, 115-125 (1992)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     CDS             157..2988
                     /product="centromere autoantigen C"
                     /gene="CENPC"
                     /evidence=EXPERIMENTAL
                     /codon_start=1
                     /translation="MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEE
                     KSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVE
                     PSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPS
                     VLLDAKTSVSQNVIPSSAKKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKI
                     EIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSES
                     SPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISP
                     AESTALFQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIDETV
                     NNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHIT
                     QDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKL
                     VPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQ
                     SSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEAD
                     LAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLE
                     ESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRT
                     KRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKR
                     ICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDLVRPQDTYQFFVKHGEL
                     KVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGD
                     SFYVPSGNYYNIKNLRNEESVLLFTQIKR"
BASE COUNT     1164 a    542 c    630 g    796 t
ORIGIN
        1 cggatcgcag ctctcgcggc agtcgcctga gacttaaggt tattgcttgg ccgcggcctg
       61 gtattccggc gattcgtttc ttgctcggct tcctggagct gtggtccgtg tgggcttcca
      121 cctcagacag ttgcgctggc tcagcggggc cggaacatgg ctgcgtccgg tctggatcat
      181 ctcaaaaatg gctacagaag aagattttgt cgaccttcca gggcacgtga cattaacaca
      241 gagcaaggcc agaatgttct ggaaatctta caagactgtt ttgaagaaaa aagtcttgcc
      301 aatgatttta gtacaaattc tacaaaatca gtgcctaatt caacacgcaa aataaaagac
      361 acttgtattc agtcaccaag caaagagtgc cagaaatcac atccaaagtc agttccagtt
      421 tcttcaaaga agaaagaagc ctctctacag tttgttgtag aaccaagtga agccacaaac
      481 agatcagttc aggcccatga agttcatcag aaaattctgg caactgatgt tagttccaaa
      541 aatacacctg actcgaaaaa aatatcaagt agaaacataa atgatcatca cagtgaagct
      601 gatgaagaat tttacttatc cgttggctca ccttctgttc ttttggatgc aaaaacatct
      661 gtatcacaaa atgttattcc atctagtgcc aaaaagagag agacttacac ttttgaaaat
      721 tcagtaaata tgctgccttc aagtacagag gtttcagtta aaaccaaaaa aaggttaaac
      781 tttgatgata aagttatgtt aaagaaaata gaaatagata ataaagtatc agatgaagag
      841 gataaaacat cggaaggaca agaaagaaaa ccatcaggat catctcagaa tagaatacga
      901 gattcagaat atgaaattca acgacaagct aaaaaaagtt tttcaacatt gtttttagaa
      961 acagtaaaac gaaaaagtga atccagtccc attgttaggc atgcggcaac tgctccacct
     1021 cattcgtgtc ctcccgatga tacgaagttg atagaggatg aatttataat tgatgagtcg
     1081 gatcaaagtt ttgccagtag atcttggatt acaataccaa gaaaggcagg gtctctgaaa
     1141 caacgcacaa tatccccggc tgagagcact gcactctttc aaggtagaaa gtcaagagaa
     1201 aagcatcata atatattacc taagactttg gcaaatgaca aacattccca taaacctcac
     1261 ccagtagaga catctcagcc ctctgataaa acagtactgg atacaagtta tgctttgata
     1321 gatgaaacag taaataatta tagatctaca aaatatgaaa tgtattccaa gaatgcagaa
     1381 aaaccatcta gaagcaaaag gactataaaa caaaaacaga gaagaaaatt catggctaaa
     1441 ccagctgaag aacagcttga tgtgggacag tctaaagatg aaaacataca tacatcacat
     1501 attacccaag acgaatttca aagaaattca gacagaaata tggaagagca tgaagagatg
     1561 ggaaatgatt gtgtttccaa aaaacagatg ccacctgtgg gaagcaagaa aagtagcact
     1621 agaaaagata aggaagaatc taaaaagaag cgcttttcca gtgagtccaa gaacaaactt
     1681 gtacctgaag aagtgacttc aactgtcacg aaaagtcgaa gaatttccag gcgtccatct
     1741 gattggtggg tggtaaaatc agaggagagt cctgtttata gcaattcttc agtaagaaat
     1801 gaattaccaa tgcatcacaa tagtagccga aaatctacta agaaaacaaa tcagtcatct
     1861 aagaatatta ggaaaaaaac tattccactt aaaaggcaga agacagcaac taaaggcaac
     1921 caaagagtac agaagttttt aaatgctgaa ggttctggag gtatcgttgg tcatgatgaa
     1981 atttccagat gttcactgag tgagccattg gaaagtgatg aggcagactt ggctaagaag
     2041 aaaaatcttg attgttctag atctacaaga agctcaaaga atgaagataa cattatgact
     2101 gcacagaatg ttcccctaaa gcctcagacc agtggatata catgtaatat accaacagag
     2161 tcaaacttgg attctggaga gcataagact tcagttttag aggaaagtgg accttccagg
     2221 ctcaataata attatttaat gtctggaaag aatgatgtgg atgatgagga agttcatgga
     2281 agttcagatg actcaaaaca atctaaagtg ataccaaaga acagaatcca tcacaaacta
     2341 gtattgccct ccaacacacc aaatgttcgc aggaccaaga gaacacgttt gaaacctttg
     2401 gagtactggc gaggagagcg aatagattat caaggaaggc catcaggagg attcgtgatt
     2461 agtggagtac tatctccaga cacaatatcg tctaaaagga aggcaaaaga aaatattgga
     2521 aaagtcaaca aaaaatctaa taagaaaagg atctgtcttg ataacgatga aagaaagact
     2581 aacttaatgg taaatctagg tatacctctt ggagatcctt tgcagccaac gagggtaaag
     2641 gacccagaaa caagagagat tattctcatg gatcttgtaa ggccacaaga tacatatcaa
     2701 ttttttgtta agcatggtga gttgaaggta tacaagacat tggatacacc ctttttttct
     2761 actgggaaat tgatattagg accacaagaa gaaaagggaa agcagcatgt tggccaggat
     2821 atattggttt tttatgttaa ctttggtgac cttttgtgta ctttacatga aacaccttat
     2881 atattaagta ctggggattc gttctatgtt ccttcaggta actattataa catcaaaaat
     2941 ctccggaatg aggaaagtgt tcttcttttt actcagataa aaagatgaaa gatcaaccaa
     3001 ccttaaatat atgtatgtat atatgtatat gtaaaaacag tttgtatagt tggaatattt
     3061 gtctttgtaa ttacttgtga tgttttaaaa taaaaatttt attcagtttt gtgtaaaaaa
     3121 aaaaaaaaaa aa
//