From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Simian immunodeficiency virus (32H reisolate of SIVmac251 from
Date: 26 Jan 93 05:52:27 GMT
Distribution: bionet
Checksum: 60978 5

LOCUS       SIV22715MO   1122 bp ss-RNA             VRL       25-JAN-1993
DEFINITION  Simian immunodeficiency virus (32H reisolate of SIVmac251 from
            I227) gp120 (V2, V4) RNA, partial cds's.
ACCESSION   M92735
KEYWORDS    .
SOURCE      Simian immunodeficiency virus 15 months post infection cDNA to
            genomic RNA.
  ORGANISM  Simian immunodeficiency virus
            Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
            Retroviridae.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Almond,N.M., Jenkins,A.R., Slade,A., Heath,A.B., Cranage,M. and
            Kitchin,P.A.
  TITLE     Population sequence analysis of a simian immunodeficiency virus
            (32H re-isolate of SIVmac251): A virus stock used for international
            vaccine studies
  JOURNAL   AIDS Res. Hum. Retroviruses 8, 77-88 (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1122)
  AUTHORS   Almond,N.M., Jenkins,A.R., Heath,A.B., Taffs,F. and Kitchin,P.A.
  TITLE     The genetic evolution of the envelope gene of simian
            immunodeficiency virus in cynomolgus macaques infected with a
            complex virus pool
  JOURNAL   Virology 191, 996-1002 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     variation       replace(23,"")
                     /citation=[1]
                     /note="'c' in variation"
     misc_feature    1122
                     /note="end of gp120"
     CDS             1..1122
                     /partial
                     /note="Partial sequence of the PCR product of SIV gp120
                     obtained bydirect sequence analysis. The region of
                     sequence extendsfrom the end of V1 to the gp120:gp41
                     junction"
                     /product="gp120"
                     /codon_start=1
                     /translation="KIDMVNENSSCIAHNNCTGLEQEQMISCKFNMTGLKRDKKKEYN
                     ETWYSTDLVCEQGNSTDNESRCYMNHCNTSVIQESCDKHYWDTIRFRYCAPPGYALLR
                     CNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIIS
                     LNKYYNLTMKCRRPGNKTVLPVTIMSGLVFHSQPINDRPKQAWCWFGGKWKDAIKEVK
                     QTIVKHPRYTGTNNTDKINLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRNT
                     TNQKPKEQYKRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANIDWTD
                     GNQTNITMSAEVAELYRLELGDYKLVEITPIGLAPTDVKR"
     CDS             49..277
                     /gene="V2"
                     /partial
                     /product="gp120"
                     /codon_start=1
                     /translation="CTGLEQEQMISCKFNMTGLKRDKKKEYNETWYSTDLVCEQGNST
                     DNESRCYMNHCNTSVIQESCDKHYWDTIRFRY"
     CDS             796..874
                     /gene="V4"
                     /partial
                     /product="gp120"
                     /codon_start=1
                     /translation="WFLNWVEDRNTTNQKPKEQYKRNYVP"
BASE COUNT      399 a    178 c    252 g    293 t
ORIGIN      
        1 aaaatagaca tggtcaatga gaatagttct tgtatagctc ataataattg cacaggcttg
       61 gaacaagagc aaatgataag ctgtaaattc aacatgacag ggttaaaaag agacaagaaa
      121 aaggagtaca atgaaacttg gtactctaca gatttggttt gtgaacaagg gaatagcact
      181 gataatgaaa gtagatgcta catgaatcac tgtaacactt ctgttatcca agagtcttgt
      241 gacaagcatt attgggatac tattagattt aggtattgtg cacctccagg ttatgctttg
      301 cttagatgta atgacacaaa ttattcaggc tttatgccta aatgttctaa ggtggtggtc
      361 tcttcatgca caaggatgat ggagacacag acttctactt ggtttggctt taatggaact
      421 agagcagaaa atagaactta tatttactgg catggtaggg ataataggac tataattagt
      481 ttaaataagt attataatct aacaatgaaa tgtagaagac caggaaataa gacagtttta
      541 ccagtcacca ttatgtctgg attggttttc cactcacaac caatcaatga caggccaaag
      601 caggcatggt gttggtttgg aggaaaatgg aaggatgcaa taaaagaggt gaagcagacc
      661 attgtcaaac atcccaggta tactggaact aacaatactg ataaaatcaa tttgacggct
      721 cctggaggag gagatccgga agttaccttc atgtggacaa attgcagagg agagttcctc
      781 tactgtaaaa tgaattggtt tctaaattgg gtagaagata ggaatacaac taaccagaag
      841 ccaaaggaac agtataaaag gaattacgtg ccatgtcata ttagacaaat aatcaacact
      901 tggcataaag taggcaaaaa tgtttatttg cctccaagag agggagacct cacgtgtaac
      961 tccacagtga ccagtctcat agcaaacata gattggactg atggaaacca aactaatatc
     1021 accatgagtg cagaggtggc agaactgtat cgattggaat tgggagatta taaattagta
     1081 gagatcactc caattggctt ggcccccaca gatgtgaaga gg
//