From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat dihydropyridine-sesitive L-type calcium channel alpha-2 subunit
Date: 9 Apr 92 10:05:09 GMT
Distribution: bionet
Checksum: 53570     8

LOCUS       RATDHSCCA    3804 bp ss-mRNA            ROD       09-APR-1992
DEFINITION  Rat dihydropyridine-sesitive L-type calcium channel alpha-2 subunit
            (CCHL2A) gene, complete cds.
ACCESSION   M86621
KEYWORDS    dihydropyridine-sesitive L-type calcium channel alpha-2 subunit.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) young adult brain cDNA to
            mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3804)
  AUTHORS   Kim,H.-L., Kim,H., Lee,P., King,R.G. and Chin,H.
  TITLE     Rat brain expresses an alternatively spliced form of the
            dihydropyridine-sensitive L-type calcium channel alpha-2 subunit
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 3251-3255 (1992)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     CDS             155..3430
                     /product="dihydropyridine-sesitive L-type calcium channel
                     alpha-2 subunit"
                     /gene="CCHL2A"
                     /codon_start=1
                     /translation="MAAGCLLALTLTLFQSWLIGPSSEEPFPSPVTIKSWVDKMQEDL
                     VTLAKTASGVTQLADIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLAM
                     EAEKVQAAHQWREDFASNEVVYYNAKDDLDPERNESESGSQRIKPVFIEDANFGRQIS
                     YQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKRNRDEDPTLLWQVFAADRLARYYP
                     ASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVS
                     EMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKK
                     GFTFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHN
                     YDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYL
                     DALELGLVITGTLPVFNVTGQSENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPN
                     GYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEK
                     TFRTLVKSQDERYIDKGNRTYTWTPVNGTDYRYLALVLPTYSFYYIKAKIEETITQAR
                     SKKGKMKDSETLKPDNFEESGYTFIAPREYCNDLKPSDNNTEFLLNFNEFIDRKTPNN
                     PSCNTDLINRILLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENW
                     QENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVELYIQGKLLKPA
                     VVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYT
                     NQIGRFFGEIDPRMMRHLVNISLYAFNKSYDYQSVCDPGAAPKQGAGHRSAYVPSITD
                     ILQIGWWATAAAWSILQQLLLSLTFPRLLEAVEMEEDDFTASLSKQSCITEQTQYFFK
                     NDTKSFSGLLDCGNCSRIFHVEKLMNTNLVFIMVESKGTCPCDTRLLMQAEQTSDGPD
                     PCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIFGLQFILLWLVSGSRH
                     YLW"
     sig_peptide     155..226
                     /product="dihydropyridine-sesitive L-type calcium channel
                     alpha-2 subunit"
                     /gene="CCHL2A"
                     /codon_start=1
     mat_peptide     227..3427
                     /product="dihydropyridine-sesitive L-type calcium channel
                     alpha-2 subunit"
                     /gene="CCHL2A"
                     /codon_start=1
BASE COUNT     1116 a    840 c    885 g    963 t
ORIGIN
        1 tcggccccgc ccggccggcc cgcccgtgcc ctgccctgcc cgcctctctc ctcgcgccct
       61 ccggcagacg tcggcgcccc ggctcagtcc ctcgccgcgt gcagctccgc ccgctccggg
      121 ccggcaggga gggcactgat cttcgatcgc gaagatggct gctggctgcc tgctggcctt
      181 gactctgaca cttttccaat cttggctgat cggcccctcg agcgaggagc ccttcccttc
      241 gcccgtcact atcaagtcat gggtggataa aatgcaggaa gaccttgtca cactggcaaa
      301 gacagcaagt ggagtgactc agcttgctga catttatgaa aaataccaag atttgtatac
      361 tgtggagcca aataatgcac gccaactggt tgaaattgca gctagagaca ttgagaaact
      421 tctgagcaac agatctaaag ccctggtgcg cctggctatg gaagcagaga aagtccaagc
      481 cgcccaccaa tggagggaag attttgcaag caacgaagtt gtctactaca acgctaaaga
      541 cgatcttgat cctgaaagaa atgagagtga gtcaggcagc caacggatta aacctgtttt
      601 catcgaagac gctaattttg gacgccagat atcctatcaa catgcagcgg tccatattcc
      661 cacggacatc tatgagggct caaccatagt gttaaacgaa ctcaactgga caagtgcctt
      721 agatgaagtt ttcaaaagaa atcgagatga agaccctaca ttgctgtggc aagtgtttgc
      781 agccgaccgc ctggcccgat attatccagc ttctccgtgg gtggataaca gcagaactcc
      841 aaacaagatc gatctctacg atgtacgcag aagaccatgg tacatccagg gagctgcatc
      901 ccccaaagac atgctcattc tggtggacgt gagtggaagt gtgagcggat tgactctgaa
      961 actcatccgg acatctgtct ctgagatgtt agaaaccctt tccgatgatg atttcgtgaa
     1021 tgtagcttca tttaacagca atgctcagga tgtgagttgt ttccagcacc tggttcaagc
     1081 gaatgtaagg aacaagaagg tgctgaagga tgcggtgaat aacatcacag caaaggggat
     1141 aacagattac aagaaaggct ttacgttcgc gtttgaacag ctacttaatt ataatgtttc
     1201 cagagccaat tgtaataaga tcatcatgtt attcacggat ggaggagaag agagagccca
     1261 ggagatattt gccaagtaca ataaagacaa aaaagtccgc gtgtttacat tttctgttgg
     1321 tcaacataat tatgacagag gacctattca gtggatggct tgtgaaaaca aaggttatta
     1381 ttatgagatt ccctctattg gtgcaataag aatcaatact caggaatatc tagatgttct
     1441 gggaagacca atggttttag ccggggacaa agcaaagcaa gtccagtgga caaatgtgta
     1501 tttggatgct ctggagctgg gacttgtcat tactggaact ctaccggtct tcaacgtcac
     1561 tggccagtct gaaaataaga ctaacttgaa gaaccagttg attcttggtg tgatgggcgt
     1621 tgatgtgtct ctggaagata ttaagagatt gacaccacgt tttacactgt gccccaacgg
     1681 ttactatttt gcaatcgatc ctaatggtta tgtcttactg catccaaatc ttcagccaaa
     1741 gaaccccaaa tctcaggagc cggtcacact ggattttctc gatgctgagt tagagaatga
     1801 tattaaagtg gagattcgaa ataaaatgat agacggagaa agtggagaaa aaacattcag
     1861 aactctggtc aaatctcaag atgagagata tattgacaaa ggaaatcgaa catacacatg
     1921 gacacctgtc aatggcacag attacaggta tttggccttg gtattgccaa cctacagttt
     1981 ttactatata aaagccaaaa tagaagagac aataactcag gccagatcaa aaaaggggaa
     2041 aatgaaggat tcagaaaccc tgaagccaga caattttgaa gaatctggct acactttcat
     2101 agcaccaagg gaatactgca atgacctgaa accttcagat aataacactg aatttctttt
     2161 aaatttcaat gaatttattg ataggaaaac tccaaacaac ccttcctgta atacagattt
     2221 gattaataga atcttgctgg atgcgggttt tacaaatgaa cttgtccaaa attattggag
     2281 taaacagaaa aatatcaaag gagtgaaggc acgctttgtg gtgactgatg gcggaattac
     2341 aagagtttac cccaaagagg ctggagaaaa ctggcaagag aacccagaga cgtatgagga
     2401 cagcttctac aaacggagcc tagataacga taactacgtt ttcactgcgc cctacttcaa
     2461 caaaagtgga cctggtgcct atgaatctgg aattatggta agcaaagctg tagaactgta
     2521 catccaagga aaacttctta agcctgcagt tgtgggaatt aaaattgacg taaactcctg
     2581 gatagaaaat tttaccaaaa cttcaatcag ggatccgtgt gctggtccag tttgtgactg
     2641 caaaagaaac agtgatgtaa tggactgtgt cattctagat gatggtggat ttcttctgat
     2701 ggccaatcat gatgattaca ctaatcagat tggacgtttt tttggagaga ttgacccgcg
     2761 catgatgaga cacctggtta atatatcact ttatgcattc aataaatcat atgactatca
     2821 gtctgtgtgt gatccagggg cagcaccaaa gcaaggagca ggacatcgct cagcctatgt
     2881 gccatcaatt acagacatac tccagattgg ctggtgggcc actgctgccg cctggtctat
     2941 tctccagcag ctactcttga gtttgacatt tccacggctc cttgaggcag ttgaaatgga
     3001 agaggatgac ttcacagctt ccctgtctaa gcagagctgc atcacagaac aaactcagta
     3061 cttcttcaag aacgatacta aatcattcag tggtttactg gactgtggaa actgttccag
     3121 gatctttcat gttgagaagc ttatgaacac caacctagtg ttcataatgg tggagagcaa
     3181 gggaacatgt ccgtgtgaca cgcggctgct catgcaagca gaacagactt ctgatggtcc
     3241 agatccttgc gacatggtta agcagcccag ataccgaaaa ggacctgatg tctgctttga
     3301 taacaatgtg ctggaggatt ataccgactg tggtggtgtt tctggattaa acccttcctt
     3361 atggtctatc tttggactcc aatttatact cctttggctg gtatctggca gcagacacta
     3421 tctatggtga ccctctaaac ccatgatctg caacttaatt ccatgccctg ccaaaacatg
     3481 agccctcagt tacattaaaa tagagcccgt tgaagaagct ccacagaacc ttagctgggc
     3541 ctctaccctg atgtaactgt gaggcttaga ttcctgacca tcgctggctg catgtcaggg
     3601 tgttggaaac tgaaactcgt gtgaacatgc tgcatcatct gtgtccaaca tcaaagcaaa
     3661 gctctactca ttctctgtgg gaggtttggg agttcgctgt tgcactgttg gagattacgt
     3721 ggaaaaggct cccccacgca ggccttatga aaagaagcag tcttgacttt gacctagcat
     3781 ttcaacctgc tgcagtttta ccaa
//