From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Chicken src substratep80/85 (cortactin) mRNA, complete cds.
Date: 5 Jan 93 06:46:15 GMT
Distribution: bionet
Checksum: 49857 6

LOCUS       CHKPP60SRC   2460 bp ss-mRNA            VRT       04-JAN-1993
DEFINITION  Chicken src substratep80/85 (cortactin) mRNA, complete cds.
ACCESSION   M73705
KEYWORDS    p85.25; tyrosine kinase.
SOURCE      Gallus gallus 10 day old embryo whole embryo cDNA to mRNA.
  ORGANISM  Gallus gallus
            Eukaryota; Animalia; Chordata; Vertebrata; Aves; Neornithes;
            Neognathae; Galliformes; Phasianidae.
REFERENCE   1  (bases 1 to 2460)
  AUTHORS   Wu,H., Reynolds,A.B., Kanner,S.B., Vines,R.R. and Partsons,J.T.
  TITLE     Identification and characterization of a novel
            cytoskeleton-associated pp60src substrate
  JOURNAL   Mol. Cell. Biol. 11, 5113-5124 (1991)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Schuuring,E.M., Verhoeven,E., Litvinov,S., de Boer,C. and
            Michalides,R.A.
  TITLE     The product of the EMS1 gene, amplaxin, amplified and overexpressed
            in human carcinomas with a chromosome 11q13 amplification, is
            located in the cell-to-substrate contact sites
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..382
                     /product="p80/85"
                     /gene="p85.25"
                     /evidence="EXPERIMENTAL"
     3'UTR           2072..2460
                     /product="p80/85"
                     /gene="p85.25"
                     /evidence="EXPERIMENTAL"
     CDS             383..2074
                     /gene="p85.25"
                     /evidence="EXPERIMENTAL"
                     /note="amino acid sequence exhibits 84.5% homology with
                     human EMS1 gene (sequence M98343)"
                     /product="p80/85"
                     /codon_start=1
                     /translation="MTVLLLVVLQMWKATAGHSIAVSQDDGADDWETDPDFVNDVSEK
                     EQRWGAKTVKGSGHQEHINIHQLRENVFQEHQTIKEKELETGPKASHGYGGKFGVEQD
                     RMDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFEYQGKTEKHASQ
                     KDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGVDKDKVDKS
                     AVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKVQLHESQKDYKS
                     GFGGKFGVQTERQDPSAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNAATFE
                     DIEKPTSTYQKTKPVERVANKTSSIRANLENLAKEKEQEDRRKAEAERAQRMAREKQE
                     QEEARRKLEEQAKAKKQTPPPSPTTQPAEPKTPSSPVYQDAVSYDAESAYKNSSTTYS
                     AEHEPESGYKTTGSDYQEAVSQREAEYEPETVYEVAGAGDHYQAEENTYDEYENELGI
                     TAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ"
BASE COUNT      789 a    462 c    635 g    574 t
ORIGIN      
        1 ccggtgcaaa acagctattg ctatgtccta agtttgtgca cagggtgtgg aattagcagc
       61 agtcctcagg aagggacgtg gagtgggatt gctgcctgaa cagaagtcct cagtgcagag
      121 gtacaaaggg tgctaccagt gagtgaacta aaaccatgtg ttaatttgaa caaaggtctc
      181 ttccttggtc tctttaaaat ctcatcttta attgctgctg atctttgtgc agtgccagta
      241 gaaaaattaa ggatgtggct caaacagcct gagagccaat gaccacagag gtggctgatg
      301 tttgtttcct ttgctgggaa ttttgggttg cgcttctgtc agcatacata gaaggtaaag
      361 tgagtttcta tgtaacggga gcatgacggt gctgcttctg gtggtgttgc agatgtggaa
      421 ggctaccgca ggccactcca ttgccgtcag ccaggatgat ggagcagatg actgggagac
      481 agatcccgac tttgtgaatg acgtgagtga gaaagagcag cgctgggggg ctaaaactgt
      541 gaaaggatcc ggccatcaag agcacatcaa tattcatcaa ctgagagaga atgtattcca
      601 agaacaccag accatcaaag agaaggagct tgaaacagga ccaaaagctt cccatggcta
      661 tggagggaaa ttcggcgttg aacaagatcg catggataaa tcagctgttg gacacgagta
      721 ccagtcaaag ctttctaagc attgctcaca agtggattct gtgaaaggat ttggaggcaa
      781 gtttggagta caaactgaca gagttgacca gtcagctgtt gggtttgaat accaggggaa
      841 aacagagaaa catgcctccc aaaaagacta ctcaagtggt tttggtggaa aatatggagt
      901 gcaagctgac agggtggaca agagtgcagt ggggtttgat taccagggta aaaccgagaa
      961 acatgagtca caaaaagatt attccaaggg ctttggtggt aaatatggtg ttgacaagga
     1021 caaagtggac aaaagtgctg ttggctttga atatcaaggc aaaacggaaa aacatgaatc
     1081 acagaaagat tatgtgaagg ggtttggagg caagtttggt gtgcagacag acagacaaga
     1141 caaatgtgca cttggctggg atcaccagga gaaagtgcag ctgcatgaat cccagaaaga
     1201 ctataagagt ggtttcggag ggaaatttgg tgtacagaca gaaaggcagg acccatctgc
     1261 tgtggggttt gattacaagg agaaactagc caagcatgaa tctcaacaag attattcaaa
     1321 aggatttggt gggaagtacg gtgtacagaa ggatcggatg gataagaatg cagcaacttt
     1381 tgaagatatt gagaaaccaa cctcaacata tcagaaaact aagccagtag aacgtgtcgc
     1441 taataaaaca agtagcatta gagctaactt ggaaaacctc gccaaggaga aagaacagga
     1501 agaccgaagg aaggcagaag ctgagagagc acaaagaatg gcacgggaga aacaagaaca
     1561 ggaagaggct cgaaggaaac tggaggagca agctaaagcc aaaaaacaaa ctccaccacc
     1621 atctcctacc acacaaccag ctgaaccgaa gacaccctca agcccagtct accaggatgc
     1681 agtttcctat gatgcagagt ctgcctacaa gaactctagc acaacatact cagcagaaca
     1741 cgagccggaa tccggctaca aaacgacagg gtcagactac caagaagcag tgagtcagcg
     1801 agaggcagaa tatgaaccag agacagtcta tgaagtggca ggggcaggag accattacca
     1861 agcagaagaa aatacctacg atgaatatga aaatgaactt ggaattacag ccatagctct
     1921 ttatgattat caggctgcgg gtgatgacga gatctccttt gatccagatg acatcatcac
     1981 aaacatagag atgatagatg acggctggtg gaggggtgtc tgcaaaggcc gatacgggtt
     2041 gttcccagcg aattatgtgg agctgagaca atagagactg ttgtctgctg gttatgcctt
     2101 aattccccag tcaataaatc tgacctaata cactacaaat catgatgctt ttctgagaat
     2161 ggtggggtat atacatattg cttttatatt taatactttg ccgatgcttt ttaaaatgtt
     2221 tatgccacag aagttgctaa tatattgtaa ctactctgtt cttcactgag gctcttaaga
     2281 tgattttcat gcatttggaa ccattctctg ccaaattagc gattgtcgta aaaagccttt
     2341 ccaaggacaa ttagctgtct gtcataatat tgcatgtttt actcataagt gagcagattt
     2401 acctcgtgtt tagtctagtt agtcttcact aatgttcagc tcagaaatca tgcttgcggt
//