From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Equine herpesvirus type 4 protein kinase; glycoprotein G;
Date: 2 Sep 92 10:00:36 GMT
Distribution: bionet
Checksum: 59269    11

LOCUS       HSEUS12X     5449 bp ds-DNA             VRL       02-SEP-1992
DEFINITION  Equine herpesvirus type 4 protein kinase; glycoprotein G;
            glycoprotein J 5'end; (US1) gene; (US2) gene, complete cds.
ACCESSION   M89634
KEYWORDS    glycoprotein G; glycoprotein J; protein kinase.
SOURCE      Equine herpesvirus type 4 (individual_isolate 405/76) equine foetal
            DNA.
  ORGANISM  Equine herpesvirus type 4
            Viridae; ds-DNA enveloped viruses; Herpesviridae;
            Alphaherpesvirinae.
REFERENCE   1  (bases 1 to 5449)
  AUTHORS   Nagesha,H. and Studdert,M.
  TITLE     Nucleotide sequence analysis of five genes (US1 to US5) in the
            unique short region of the equine herpesvirus.strain 405/76
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             complement(49..1140)
                     /gene="US1"
                     /codon_start=1
                     /translation="MSSDMLTAATAGTEVFRCNLARRGNANPPHLVLAPTFSSATVSE
                     SNAKDGASQEPRKYLFNPYKYMLGRPYFRRCREEMNEGYFAKVPEGYFPVGPSEMPGR
                     VPVESKVDGEVLSFKALPPPKFEKRFYKQLDDGTFVRLPFLYPEEYYEGENQPSETLY
                     YIRADTKDAYSVDPSDLLEEAFAEVPKWLEEEMSNWTGPKKLPIPSRRYVLKHGWEFQ
                     SNVTEDAFQEINTTFLRLDLQGEPKQHTRNAQQSSIGDQVLDAHPRDAQQPKNGNSVD
                     KNSDKPGRCCLTPACSSRGSAGGRRGDTGGDAWPHGRRRRARRCPVRDIRDRRGVPRA
                     RISGDANRGRGHRLYRHDFPPCCPAPASQ"
     TATA_signal     complement(1162..1167)
                     /gene="US1"
     polyA_signal    complement(1232..1237)
     CDS             complement(1234..2208)
                     /gene="US2"
                     /codon_start=1
                     /translation="MGVVLITVVMVVDRHKALPDSSIDVDGKLWEFLGRLCFVLASEP
                     LGIPIVVRSADLYKFSSSLLALPKACRPIVRTRGATAIALERNGVIYQEDRIGISIEW
                     LSVLSGYNYLNSSIIINRPYHLWVLGAADLCRPVFNLIPGPKRIVYVEIEDEFNKSWQ
                     PSFVCGKLFETIPLTTVDYKHLLKQKVLPGQDHPESARSLLQHKSSFVSPPPNFKRLI
                     YAVVDPMRLQENLCPQITNRTKTKRRSKKTYNGLFCQESTASLNDKMCFTPQPSKGKN
                     LQRVSTSMQANSTIPPSTLSPRAAARKPTEMTWKSRLLGGVFDRTARR"
     TATA_signal     complement(2317..2322)
                     /gene="US2"
     CAAT_signal     2356..2359
     CAAT_signal     complement(2370..2373)
     TATA_signal     2391..2395
     CDS             2514..3500
                     /product="protein kinase"
                     /codon_start=1
                     /translation="MATLNVVTADSASESDEDDDRWLMPPKEKAKEVAASFGFKVIKT
                     LTPGSEGRVMVATKEGQPDQVVLKIGQKGTTLIEAMMLRNVNHPCVIKMKDTLVSGGI
                     TCMVLPHYNSDLYTFLTRRSTRIPIDQALIIERQILEGLRYLHAQRIIHRDVKTENIF
                     INSVDQVCIADFGAAQFPVVDPMDLGLAGTVETNAPEVLARAKYNSKVDIWSAGIVLF
                     EMLAYPSTLFEDPPSTPQEYVKSCHSQLLRIISKLKINPEEFPREPESRLVRGYIEYA
                     SLERNRHTRYPCFQRVNLHMTGEFLIHKMLAFNAAMRPSAEELLSYPMFMNL"
     CAAT_signal     3481..3485
     TATA_signal     3545..3550
     CDS             3624..4841
                     /product="glycoprotein G"
                     /codon_start=1
                     /translation="MLAVGATLCLLSFLTGATGRLAPDDLCYAEPRKTGPMPRSKPKH
                     QPLLFEAPKVALTAESKGCQLILLDPPIDMGYRLEDKINASIAWFFDFGNCRMPIAYR
                     EYYDCVGNAIPSPETCDGYSFTLVKTEGVVEFTIVNMSLLLQPGIYDSGSFIYSALLD
                     MDVLTGRVILNVENDTNYPCGMTHGLTADGNINVDETTHTTPHPRAVGCFPELINFDA
                     WENVTFEEMGIPDPNSFLDDESDYPNTMDCYSWDLYTYPKSLKQAEGPQTLLIGAVGL
                     RILAQAWKFVENETYSQHTRTYTRDAKEVDVTQPSPVQADSVLAKKRTSMKNNPIYSE
                     GKPHAKPFSTIDSIHTEGMKNNPVYSESLMLNVQHSDSITTGGVLHGLQDCDNQLKTV
                     YICLALIGLAHVP"
     polyA_signal    4965..4970
     CAAT_signal     5036..5039
     TATA_signal     5077..5082
     CDS             5100..>5447
                     /product="glycoprotein J"
                     /codon_start=1
                     /translation="MSFGRGLTTLGSSLMQILHAAVVFMHRATTAETTTASSSTSGST
                     QSASSETNSSSSPTTGPTTTSSQTSSSNSTQTPSTSQTPTTSSSTVSTTTTSNSTNES
                     STATATSTATPTST"
BASE COUNT     1498 a   1284 c   1261 g   1406 t
ORIGIN
        1 gggccatcga acaaacgcgc agaggctggg gttctctact atgaggtttt attgactggc
       61 gggtgcggga cagcagggtg ggaaatcgtg gcggtagagg cgatggccgc gtccgcggtt
      121 cgcgtcacct gaaatacgcg cgcgaggaac gccccgacga tcccggatat cgcgcacagg
      181 acagcgacga gcacgacgcc ggcgaccgtg aggccacgcg tcgccgcctg tgtcgccgcg
      241 cctgccgccg gccgaccctc tggatgaaca ggctggcgtt aaacagcaac gaccaggctt
      301 gtctgagttt ttatcaaccg aatttccatt ttttggctgt tgggcatctc tgggatgtgc
      361 atctaaaact tgatcaccga tgcttgattg ttgagcattt ctggtatgct gttttggttc
      421 accctgaaga tctaggcgta aaaaggttgt gtttatttcc tgaaacgcat cttctgtaac
      481 gtttgactgg aactcccatc catgttttag tacatagcgc ctagatggta tgggcaattt
      541 ctttggacca gtccagtttg acatttcctc ttctagccat tttggaacct cagcaaatgc
      601 ttcttcaagc agatcactcg gatcgacgct gtaagcatct tttgtgtctg ctctgatgta
      661 gtaaagtgtt tctgatggtt gattttctcc ctcgtagtac tcttctggat ataaaaatgg
      721 caatcggaca aatgttccat cgtccagctg cttgtagaat cgcttttcaa actttggagg
      781 tggtagggcc ttaaagctga gcacttcgcc atcaacttta ctttcaactg gaacacggcc
      841 aggcatctca ctcggtccaa ctggaaagta gccttcgggt acctttgcaa agtacccctc
      901 gttcatttct tcgcgacaac gtctgaagta tggccgccca agcatatact tatatgggtt
      961 aaagagatat ttgcgcggtt cttgagaagc gccgtccttg gcgttggact cgctcacagt
     1021 tgcagatgaa aaggtgggtg ccaaaactag atgcggtgga ttagcgttgc cgcggcgagc
     1081 aagattacag cgaaaaactt cggtgcctgc agtggcggct gtaagcatgt cggagctcat
     1141 gtctaaagat agacgtgaag tttgtaagta aaaatctcac aggaaaccac acttggcaaa
     1201 gcgcagtgac tagcaaagag cttccccaac cttttaacgt ctggctgttc tatcaaacac
     1261 accccctagt aggcgtgatt tccacgtcat ttctgtgggt ttccgggcag ctgcacgagg
     1321 agatagggtg ctaggtggta ttgtagagtt ggcttgcatc gacgtgctaa cgcgctgcaa
     1381 gtttttgcct tttgatggct gtggagtaaa acacatctta tcgtttaggc tggctgtaga
     1441 ctcttggcaa aacaggccat tataagtttt tttagaacgt cttttagttt ttgttctgtt
     1501 agttatttgt ggacataaat tctcttgtaa acgcataggg tctacaaccg cataaattaa
     1561 ccgcttaaaa tttggcgggg gagatacaaa agatgattta tgttgtaata aactgcgcgc
     1621 gctctcaggg tggtcttgtc cgggtaaaac cttttgtttt agtagatgct tataatccac
     1681 ggttgtcaac ggtattgttt cgaatagttt tccgcacacg aagctgggct gccaagattt
     1741 attaaactca tcttcgatct ccacatacac aattcgcttg gggcccggta tgaggttgaa
     1801 cacaggcctg cataaatctg cagctcccaa aacccatagg tggtatggcc tattgatgat
     1861 aatgctggag ttgaggtagt tgtagccgga tagtacagaa agccactcta tactaatgcc
     1921 aattctatcc tcttgataaa tcacgccatt tctttctagg gctatagcag tagcccccct
     1981 agttctcact ataggcctgc atgcttttgg cagggctaag agactcgaag aaaatttgta
     2041 caggtcagca gaacgcacca ctattggtat tcctagaggt tctgaggcta atacaaaaca
     2101 tagtcgtccc aaaaactccc acagttttcc atctacgtcg atagaactgt cgggcaaagc
     2161 tttatgcctg tcaaccacca tgacaactgt aattaaaacc acacccatgt tattagcaaa
     2221 tgggtgtgtt aaaccaaccc aataaatttc agcagagctg ctctagctac acactttgtt
     2281 gtgaaaaaga cttgctgtgt tacgggattc gtagctttat aagcacacgc ccacagcatc
     2341 ggcatggaaa ataaacaata cgaccaccta ttgtccgact ggctatccgg taatattagc
     2401 gaggcatctg aatcgatgga tacgacaccc ccactacagc tttctgtaca tcctcaaaat
     2461 ccaagctgtg ggggggcagc cgctaatgag gaccctgtac tcagacataa gcgatggcga
     2521 ccttgaatgt agtgactgcc gatagtgcat ctgagagcga tgaagacgat gaccgatggc
     2581 taatgccccc aaaagaaaag gcgaaggaag tggctgcttc atttgggttc aaggtcatta
     2641 aaacgctaac tcctggctca gaggggcgtg ttatggttgc aacaaaggag ggccagccag
     2701 accaggtcgt attgaagatt ggccaaaagg gaactacgct catcgaagcc atgatgctaa
     2761 gaaacgtaaa ccacccatgc gtgattaaaa tgaaggacac cctagtgtct ggtggaataa
     2821 cttgcatggt actacctcac tacaattcgg atctgtacac atttttgact cggcgatcaa
     2881 cgcgtatacc tattgatcag gcattgatta tagaacgaca gattctagag gggctgcggt
     2941 accttcacgc acagcggatc atacacagag atgttaagac tgaaaatatt tttataaaca
     3001 gcgtcgatca agtgtgcata gcagactttg gagcagcaca atttccggtt gtggacccca
     3061 tggaccttgg tttggctggt accgtggaaa ctaacgctcc ggaagttttg gccagagcaa
     3121 aatacaattc gaaggtagac atatggagcg ccggaatagt tctgtttgaa atgctcgcat
     3181 atccatcaac tctatttgag gacccgccga gtaccccaca agagtatgta aaaagctgtc
     3241 attctcaact actgagaata atatcaaagc taaagataaa ccctgaggag tttccacggg
     3301 aaccagagtc taggctcgtg cgcggataca tcgaatacgc cagcctagag cgtaaccgac
     3361 atacgcgcta tccttgcttc cagcgcgtga acctacacat gacgggggaa tttttgatcc
     3421 ataaaatgct agcgttcaat gctgcgatgc gcccatccgc agaagagttg ttgtcctacc
     3481 caatgtttat gaatctgtag gatgactaac agatttgggg tggagacggc gtgggccgat
     3541 actgtataaa gttgtactac ttaccagccc agtcagtgtg ctgtagtgcc accacctgta
     3601 aagctgtgat aagctgcagg catatgttgg ctgtgggagc aactctgtgt ttactgagtt
     3661 tcctaactgg cgctactgga cggctagctc ctgacgacct ctgctatgca gaaccccgca
     3721 aaaccggtcc catgccccgc tcaaaaccta aacaccaacc cctactattt gaagccccaa
     3781 aggttgctct tacggcagag tcaaagggtt gtcaactaat attgttagac cctccaatag
     3841 acatgggcta tcgcttagag gacaagataa acgcttccat tgcttggttt tttgactttg
     3901 gtaattgtcg aatgcccatc gcatacagag agtactatga ttgcgttggc aacgcaatcc
     3961 catctccaga aacatgtgat ggttactcat ttacacttgt taaaacagag ggtgtagttg
     4021 agtttaccat cgtaaacatg agcttactgt tgcagcctgg aatatacgac agtggaagtt
     4081 ttatatacag cgcccttcta gatatggatg tattgactgg acgcgtaatt ttgaacgtgg
     4141 agaacgacac taactatcca tgcggaatga ctcacggcct cactgcggat ggcaacatca
     4201 acgtagatga aaccacgcac acaaccccac atccacgtgc tgtcgggtgt tttccagaac
     4261 tcattaactt cgatgcatgg gaaaacgtta cattcgaaga aatggggata ccagacccaa
     4321 actcatttct tgatgatgag agtgattacc cgaatacaat ggactgttac tcgtgggatt
     4381 tatacacata tcccaaaagc ctgaagcagg cagaggggcc ccaaaccttg ttaataggtg
     4441 cagttggact cagaatactc gcgcaagcat ggaagtttgt tgaaaatgaa acctacagcc
     4501 agcatacacg tacgtacaca cgtgatgcta aggaagttga tgttacacag ccaagtcctg
     4561 tacaggctga ttctgtcctc gccaagaaac gcacatctat gaagaataac cctatttatt
     4621 cagaggggaa gcctcatgct aaaccgttca gcacgataga cagcatccac acggaaggga
     4681 tgaagaataa ccctgtttat tcagagagcc tcatgctaaa cgtccagcac agtgacagca
     4741 tcaccaccgg gggtgtgttg catggcctcc aagactgcga caaccagctc aaaactgtgt
     4801 atatttgcct agctcttatt ggactcgcac atgtgccatg ataggactaa tagtttacat
     4861 ttttgtgcta aggtcaaaaa tatcttccca caatttatcg cgctcacaaa atgtaaaaca
     4921 tagaaactat catcgacttg agtacgttgc ataatacatg tcaaaataaa agttaaaaat
     4981 taaacattgt tgtctgtaat aactgagtgt ggttttaaaa aatactaaat cgcggcaatg
     5041 ttgcaaacgg tcctctacaa aagagagggt tgatggtata tatgaaatag tccccttgca
     5101 tgagttttgg tagaggtcta actacgctag ggtcatcatt gatgcagata ctgcatgctg
     5161 cagttgtatt tatgcatagg gcaacaaccg cggaaactac taccgctagc tcgtcaactt
     5221 ctggaagtac ccagtccgcg tctagcgaaa ctaatagtag tagttccccc accacgggcc
     5281 ccactaccac atcttcccaa acatcctctt ctaactctac ccaaacacct tcaacgtctc
     5341 aaacacccac tactagctcg tctaccgttt ccacaactac tacttcaaac tcaacaaacg
     5401 aaagttctac tgcgacggct acatcaactg caactccaac atccacaga
//