From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human pHL-1 gene is a c-myc oncogene containing coxIII sequence
Date: 24 Jul 92 10:07:10 GMT
Distribution: bionet
Checksum: 60344     4

LOCUS       HUMPHL1      1941 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  Human pHL-1 gene is a c-myc oncogene containing coxIII sequence
ACCESSION   X54629
KEYWORDS    c-myc oncogene; cytochrome c oxidase subunit III; oncogene.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Shay,J.W., Baba,T., Zhan,Q., Kamimura,N. and Cuthbert,J.A.
  TITLE     HeLaTG cells have mitochondrial DNA inserted into the c-myc
            oncogene.
  JOURNAL   Oncogene 6, 1869-1874 (1991)
  STANDARD  full automatic
COMMENT     *source: cell_line=HELATG;
            See also V00662 for coxIII sequence. pHL-1 (nucleotides 1-774)
            shows 99.5% similarity to coxIII nucleotides 9217-9990.  See also
            PNAS 80:519-524 and 1707-1711(1983) for c-myc sequences. pHL-1
            c-myc sequence shows just one nucleotide substitution difference.
            From EMBL    entry HSPHL1;  dated 04-NOV-1991.
FEATURES             Location/Qualifiers
     misc_feature    1..774
                     /note="99.5% homology with coxIII mtDNA"
                     /note="putative"
     misc_feature    775..1941
                     /note="c-myc sequence, virtually identical to partof exons
                     2+3"
BASE COUNT      563 a    391 c    483 g    504 t
ORIGIN
        1 aagaccctca tcaatagatg gagacataca gaaatagtca aaccacatct accaaatgcc
       61 agtatcaggc ggcggcttcg aagccaaagt gatgtttgga tgtaaagtga aatattagtt
      121 ggcggatgaa gcagatagtg aggaaagttg agccaataat gacgtgaagt ccgtggaagc
      181 ctgtggctac aaaaaatgtt gagccgtaga tgccgtcgga aatggtgaag ggagactcga
      241 agtactctga ggcttgtagg agggtaaaat agagacccag taaaattgta ataagcagtg
      301 cttgaattat ttggtttcgg ttgttttcta ttagactatg gtgagctcag gtgattgata
      361 ctcctgatgc gagtaatacg gatgtgttta ggagtgggac ttctagggga tttagcgggg
      421 tgatgcctgt tgggggccag tgccctccta gttggggggt aggggctagg ctggagtggt
      481 aaaaggctca gaaaaatcct gcgaagaaaa aaacttctga ggtaataaat aggattatcc
      541 catatcgaag gcctttttgg acaggtggtg tgtggtggcc ttggtatgtg ctttctcgtg
      601 ttacatcgcg ccatcattgg tatatggtta gtgtgttggt tagtaggcct agtatgagga
      661 gcgttatgga gtggaagtga aatcacatgg ctaggccgga ggtcattagg agggctgaga
      721 gggcccctgt taggggtcat gggctgggtt ttactatatg ataggcatgt gatttcctgc
      781 gcctcgcaag actccagcgc cttctctccg tcctcggatt ctctgctctc ctcgacggag
      841 tcctccccgc aggcagcccc gagcccctgg tgctccatga ggagacaccg cccaccacca
      901 gcagcgactc tgaggaggaa caagaagatg aggaagaaat cgatgttgtt tctgtggaaa
      961 agaggcaggc tcctggcaaa aggtcagagt ctggatcacc ttctgctgga ggccacagca
     1021 aacctcctca cagcccactg gtcctcaaga ggtgccacgt ctccacacat cagcacaact
     1081 acgcagcgcc tccctccact cggaaggact atcctgctgc caagagggtc aagttggaca
     1141 gtgtcagagt cctgagacag atcagcaaca accgaaaatg caccagcccc aggtcctcgg
     1201 acaccgagga gaatgtcaag aggcgaacac acaacgtctt ggagcgccag aggaggaacg
     1261 agctaaaacg gagctttttt gccctgcgtg accagatccc ggagttggaa aacaatgaaa
     1321 aggcccccaa ggtagttatc cttaaaaaag ccacagcata catcctgtcc gtccaagcag
     1381 aggagcaaaa gctcatttct gaagaggact tgttgcggaa acgacgagaa cagttgaaac
     1441 acaaacttga acagctacgg aactcttgtg cgtaaggaaa agtaaggaaa acgattcctt
     1501 ctaacagaaa tgtcctgagc aatcgcctat gaacttgttt caaatgcatg atcaaatgca
     1561 acctcacaac cttggctgag tcttgagact gaaagattta gccataatgt aaactgcctc
     1621 aaattggact ttgggcataa aagaactttt ttatgcttac catctttttt ttttctttaa
     1681 cagatttgta tttaagaatt gtttttaaaa aattttaaga tttacacaat gtttctctgt
     1741 aaatattgcc attaaatgta aataacttta ataaaacgtt tatagcagtt acacagaatt
     1801 tcaatcctag tatatagtac ctagtattat aggtactata aaccctaatt ttttttattt
     1861 aagtacattt tgctttttaa agttgatttt tttctattgt ttttagaaaa aataaaataa
     1921 ctggcaaata tatcattgag c
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