From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mRNA for long-chain acyl-CoA synthetase.
Date: 9 Apr 92 10:03:49 GMT
Distribution: bionet
Checksum: 21318     7

LOCUS       HUMLCACS     3634 bp ss-mRNA            PRI       09-APR-1992
DEFINITION  Human mRNA for long-chain acyl-CoA synthetase.
ACCESSION   D10040
KEYWORDS    long-chain acyl-CoA synthetase.
SOURCE      Human, cDNA to mRNA, clone pHACS1.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3634)
  AUTHORS   Abe,T., Fujino,T., Fukuyama,R., Minoshima,S., Shimizu,N., Toh,H.,
            Hashimoto,T., Suzuki,H. and Yamamoto,T.
  TITLE     Human long-chain acyl-CoA synthetase
  JOURNAL   J. Biochem. (1991) In press
  STANDARD  full staff_review
COMMENT     Data kindly submitted in computer readable form by:
            Tokuo Yamamoto
            Tohoku University
            Gene Research Center
            1-1 Tsutsumidouri-Amamiyamachi
            Aoba-ku, Sendai 981
            Japan
            Phone:  022-272-4321
            Fax:    022-272-1870
FEATURES             Location/Qualifiers
     CDS             14..2110
                     /EC_number="6.2.1.3"
                     /product="long-chain acyl-CoA synthetase"
                     /codon_start=1
                     /translation="MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWY
                     ATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQV
                     SNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEW
                     VIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLI
                     PGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFT
                     SGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVM
                     LCHGAKIGFFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDF
                     ASKRKEAELRSGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAAL
                     GCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEV
                     CVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGE
                     YIAPEKIENIYMRSEPVAQVFVHGESLQAFLIAIVVPDVETLCSWAQKRGFEGSFEEL
                     CRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNGLLTPTMKAKRPELR
                     NYFRSQIDDLYSTIKV"
BASE COUNT     1025 a    771 c    857 g    981 t
ORIGIN      chromosome 4.
        1 tcaacacagg acaatgcaag cccatgagct gttccggtat tttcgaatgc cagagctggt
       61 tgacttccga cagtacgtgc gtactcttcc gaccaacacg cttatgggct tcggagcttt
      121 tgcagcactc accaccttct ggtacgccac gagacccaaa cccctgaagc cgccatgcga
      181 cctctccatg cagtcagtgg aagtggcggg tagtggtggt gcacgaagat ccgcactact
      241 tgacagcgac gagcccttgg tgtatttcta tgatgatgtc acaacattat acgaaggttt
      301 ccagagggga atacaggtgt caaataatgg cccttgttta ggctctcgga aaccagacca
      361 accctatgaa tggctttcat ataaacaggt tgcagaattg tcggagtgca taggctcagc
      421 actgatccag aagggcttca agactgcccc agatcagttc attggcatct ttgctcaaaa
      481 tagacctgag tgggtgatta ttgaacaagg atgctttgct tattcgatgg tgatcgttcc
      541 actttatgat acccttggaa atgaagccat cacgtacata gtcaacaaag ctgaactctc
      601 tctggttttt gttgacaagc cagagaaggc caaactctta ttagagggtg tagaaaataa
      661 gttaatacca ggccttaaaa tcatagttgt catggatgcc tacggcagtg aactggtgga
      721 acgaggccag aggtgtgggg tggaagtcac cagcatgaag gcgatggagg acctgggaag
      781 agccaacaga cggaagccca agcctccagc acctgaagat cttgcagtaa tttgtttcac
      841 aagtggaact acaggcaacc ccaaaggagc aatggtcact caccgaaaca tagtgagcga
      901 ttgttcagct tttgtgaaag caacagagaa tacagtcaat ccttgcccag atgatacttt
      961 gatatctttc ttgcctctcg cccatatgtt tgagagagtt gtagagtgtg taatgctgtg
     1021 tcatggagct aaaatcggat ttttccaagg agatatcagg ctgctcatgg atgacctcaa
     1081 ggtgcttcaa cccactgtct tccccgtggt tccaagactg ctgaaccgga tgtttgaccg
     1141 aattttcgga caagcaaaca ccacgctgaa gcgatggctc ttggactttg cctccaagag
     1201 gaaagaagca gagcttcgca gcggcatcat cagaaacaac agcctgtggg accggctgat
     1261 cttccacaaa gtacagtcga gcctgggcgg aagagtccgg ctgatggtga caggagccgc
     1321 cccggtgtct gccactgtgc tgacgttcct cagagcagcc ctgggctgtc agttttatga
     1381 aggatacgga cagacagagt gcactgccgg gtgctgccta accatgcctg gagactggac
     1441 cgcaggccat gttggggccc cgatgccgtg caatttgata aaacttgttg atgtggaaga
     1501 aatgaattac atggctgccg agggcgaggg cgaggtgtgt gtgaaagggc caaatgtatt
     1561 tcagggctac ttgaaggacc cagcgaaaac agcagaagct ttggacaaag acggctggtt
     1621 acacacaggg gacattggaa aatggttacc aaatggcacc ttgaaaatta tcgaccggaa
     1681 aaagcacata tttaagctgg cacaaggaga atacatagcc cctgaaaaga ttgaaaatat
     1741 ctacatgcga agtgagcctg ttgctcaggt gtttgtccac ggagaaagcc tgcaggcatt
     1801 tctcattgca attgtggtac cagatgttga gacattatgt tcctgggccc aaaagagagg
     1861 atttgaaggg tcgtttgagg aactgtgcag aaataaggat gtcaaaaaag ctatcctcga
     1921 agatatggtg agacttggga aggattctgg tctgaaacca tttgaacagg tcaaaggcat
     1981 cacattgcac cctgaattat tttctatcga caatggcctt ctgactccaa caatgaaggc
     2041 gaaaaggcca gagctgcgga actatttcag gtcgcagata gatgacctct attccactat
     2101 caaggtttag tgtgaagaag aaagctcaga ggaaatggca cagttccaca atctcttctc
     2161 ctgctgatgg ccttcatgtt gttaattttg aatacagcaa gtgtagggaa ggaagcgttc
     2221 gtgtttgact tgtccattcg gggttcttct cataggaatg ctagaggaaa cagaacaccg
     2281 ccttacagtc acctcatgtt gcagaccatg tttatggtaa tacacacttt ccaaaatgag
     2341 ccttaaaaat tgtaaagggg atactataaa tgtgctaagt tatttgagac ttcctcagtt
     2401 taaaaagtgg gttttaaatc ttctgtctcc ctgcttttct aatcaagggg ttaggacttt
     2461 gctatctctg agatgtctgc tacttgctgc aaattctgca gctgtctgct gctctaaaga
     2521 gtacagtgca ctagagggaa gtgttccctt taaaaataag aacaactgtc ctggctggag
     2581 aatctcacaa gcggaccaga gatcttttta aatccctgct actgtccctt ctcacaggca
     2641 ttcacagaac ccttctgatt cgtaagggtt acgaaactca tgttcttctc cagtcccctg
     2701 tggtttctgt tggagcataa ggtttccagt aagcgggagg gcagatccaa ctcagaacca
     2761 tgcagataag gagcctctgg caaatgggtg ctcatcagaa cgcgtggatt ctctttcatg
     2821 gcagaatgct cttggactcg gttctccagg cctgattccc cgactccatc ctttttcagg
     2881 ggttatttaa aaatctgcct tagattctat agtgaagaca agcatttcaa gaaagagtta
     2941 cctggatcag ccatgctcag ctgtgacgcc tgaataactg tctactttat cttcactgaa
     3001 ccactcactc tgtgtaaagg ccaacagatt tttaatgtgg ttttcatatc aaaagatcat
     3061 gttgggatta acttgccttt ttccccaaaa aataaactct caggcaagca tttctttaaa
     3121 gctattaagg gagtatatac ttgagtactt attgaaatgg acagtaataa gcaaatgttc
     3181 ttataatgct acctgatttc tatgaaatgt gtttgacaag ccaaaattct aggatgtaga
     3241 aatctggaaa gttcatttcc tgggattcac ttctccaggg attttttaaa gttaatttgg
     3301 gaaattaaca gcagttcact ttattgtgag tctttgccac atttgactga attgagctgt
     3361 catttgtaca tttaaagcag ctgttttggg gtctgtgaga gtacatgtat tatatacaag
     3421 cacaacaggg cttgcactaa agaattgtca ttgtaataac actacttggt agcctaactt
     3481 catatatgta ttcttaattg cacaaaaagt caataatttg tcaccttggg gttttgaatg
     3541 tttgctttaa gtgttggcta tttctatgtt ttataaacca aaacaaaatt tccaaaaaca
     3601 atgaaggaaa ccaaaataaa tatttctgca tttc
//