From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Influenza A/Great Lakes/0389/65 (H2N2), polymerase 2 (seg 1), RNA.
Date: 31 Dec 92 01:34:33 GMT
Distribution: bionet
Checksum: 29649 5

LOCUS       FLAP2B       2329 bp ss-RNA             VRL       17-DEC-1992
DEFINITION  Influenza A/Great Lakes/0389/65 (H2N2), polymerase 2 (seg 1), RNA.
ACCESSION   M91713
KEYWORDS    PB2 polymerase; polymerase 2.
SOURCE      Influenza virus type A (individual_isolate A/Great Lakes/0389/65)
            RNA.
  ORGANISM  Influenza virus type A
            Viridae; ss-RNA enveloped viruses; Negative strand RNA viruses;
            Orthomyxoviridae; Influenzavirus; Influenza A viruses.
REFERENCE   1  (bases 1 to 2329)
  AUTHORS   Lawson,C.M., Subbarao,E.K. and Murphy,B.R.
  TITLE     Nucleotide sequence changes in the polymerase basic protein 2 gene
            of temperature-sensitive mutants of influenza A virus
  JOURNAL   Virology 191, 506-510 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             22..2301
                     /note="polymerase basic protein 2 gene; putative"
                     /product="polymerase 2"
                     /codon_start=1
                     /translation="MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPL
                     LRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRN
                     GPMTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQ
                     DVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFL
                     PVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADP
                     LASLLEMCHSTLIRGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTS
                     GSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKVTRRLVQLIVSGRDEQ
                     SIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWG
                     IEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQR
                     GNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQ
                     NPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFATA
                     PPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDEG
                     TSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRD
                     SSILTDSQTATKRIRMAIN"
BASE COUNT      788 a    414 c    588 g    539 t
ORIGIN      
        1 agcaggtcaa ttatattcaa tatggaaaga ataaaagaac tacggaatct gatgtcgcag
       61 tctcgcactc gcgagatact aacaaaaacc acagtggacc atatggccat aattaagaag
      121 tacacatcag ggagacagga gaagaacccg ttacttagga tgaaatggat gatggcaatg
      181 aaatatccga ttacagctga caagaggata acagaaatgg ttcctgagag aaatgagcaa
      241 ggacaaactc tatggagtaa aatgagtgat gccgggtcag atcgagtgat ggtatcacct
      301 ttggcagtga catggtggaa tagaaatgga ccaatgacaa gtacggttca ttatccaaaa
      361 gtctacaaga cttattttga gaaagtcgaa aggttaaaac atggaacctt tggccctgtc
      421 cattttagaa accaagtcaa aatacgccga agagttgaca taaaccctgg tcatgcagac
      481 ctcagtgcca aggaggcaca ggatgtaatc atggaagttg ttttccccaa tgaagtgggg
      541 gccaggatac taacgtcgga atcacaatta acaataacca aagagaaaaa agaagaactc
      601 caagattgca aaatttctcc tttgatggtt gcatacatgt tagagagaga acttgtccga
      661 aaaacgagat ttctcccagt tgctggtgga acaagcagtg tgtacattga agtgttacac
      721 ttgactcaag gaacgtgttg ggaacagatg tacactccag gtggagaagt gaggaatgac
      781 gatgttgacc aaagcctaat tattgcagcc aggaacatag tgagaagagc agcagtatca
      841 gcagatccac tagcatcttt attggagatg tgccacagca cactgattcg cgggacaagg
      901 atggtggaca ttcttaggca gaacccgacg gaagaacaag ctgtggatat atgcaaggct
      961 gcaatgggac tgaggatcag ctcatccttc agttttggtg ggttcacatt taagagaaca
     1021 agcgggtcat caatcaagag agaggaagaa gtgcttacgg gcaatctcca aacattgaaa
     1081 ataagggtgc atgaggggta cgaggagttc acaatggtgg ggaaaagggc aacagctata
     1141 ctcagaaaag taaccaggag attggttcag ctgatagtga gtggaaggga cgagcagtcg
     1201 atagccgaag cgataattgt agccatggtg ttttcacaag aggattgcat gataaaagca
     1261 gttagaggtg acctgaattt cgttaatagg gcaaatcagc ggttgaatcc catgcatcaa
     1321 cttttaaggc attttcagaa agatgcgaaa gtgctttttc aaaattgggg aattgaacat
     1381 atcgacaatg tgatgggaat ggttggagta ttaccagaca tgactccaag cacagagatg
     1441 tcaatgagag gaataagagt cagcaaaatg ggcgtggatg aatactccag cacagagagg
     1501 gtagtggtta gcattgatcg gtttttgaga gttcgagacc aacgtggaaa tgtattacta
     1561 tctcctgagg aggtcagtga aacacaggga acagagaaac tgacaataac ttactcatcg
     1621 tcaatgatgt gggagattaa tggccctgag tcagtgttgg tcaataccta tcagtggatc
     1681 atcagaaact gggaaactgt taaaattcaa tggtctcaga atcctacaat gctatacaac
     1741 aaaatggaat ttgagccatt tcagtcttta gttcctaagg ccattagagg ccaatacagt
     1801 ggatttgtta ggactctatt ccaacaaatg agggatgtac ttgggacatt tgataccacc
     1861 cagataataa agcttctccc ctttgcaacc gccccaccaa agcaaagtag aatgcagttc
     1921 tcttcattga ctgtgaatgt gaggggatca gggatgagaa tacttgtaag gggcaattct
     1981 cctgtattca actacaacaa gaccactaaa agactaacaa ttctcggaaa agatgctggc
     2041 actttaattg aagacccaga tgaaggcaca tccggagtgg agtccgctgt tctgagagga
     2101 ttcctcattc tgggtaagga agatagaaga tatggaccag cattaagcat caatgaactg
     2161 agtaaccttg caaaaggaga aaaggctaat gtgctaattg ggcaaggaga cgtggtgttg
     2221 gtaatgaaac gaaaacggga ctctagcata cttactgaca gccagacagc gaccaaaaga
     2281 attcggatgg ccatcaatta atgttgaata gtttaaaaac gaccttgtt
//