From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus insulin receptor-related receptor-alpha subunit
Date: 11 Sep 92 10:06:57 GMT
Distribution: bionet
Checksum: 21574     6

LOCUS       RATIRRB      1842 bp ss-mRNA            ROD       11-SEP-1992
DEFINITION  Rattus norvegicus insulin receptor-related receptor-alpha subunit
            mRNA, complete cds.
ACCESSION   M90661
KEYWORDS    insulin receptor-related protein;
            insulin receptor-related receptor-alpha subunit.
SOURCE      Rattus norvegicus (strain Wistar) kidney; stomach cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Shier,P. and Watt,V.M.
  TITLE     Tissue-specific expression of the rat insulin receptor-related
            receptor gene
  JOURNAL   Mol. Endocrinol. 6, 723-729 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            <1..483
                     /number=1
     5'UTR           <1..398
     sig_peptide     399..476
                     /codon_start=1
     CDS             399..>1842
                     /product="insulin receptor-related receptor-alpha subunit"
                     /codon_start=1
                     /translation="MAVPALWPWGVYLLMSLLSLGSCLDTLEVCPSLDIRSEVTELRR
                     LENCSVVEGHLQILLMFAATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLA
                     VIRGARLFLGYALIIFEMPHLRDIGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQP
                     APGANHIVGNKLGEECADVCPGVLGAAGEPCVRTTFGGHTDYRCWTSSHCQRVCPCPR
                     GLACTVGGECCHSECLGGCSQPEDPRACVACRHLYFQGVCLPACPPGTYQYESWRCVT
                     AELCGHLREVPGHATAFGIYEGSCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKT
                     IDSVQATQDLVGCTHVEGSLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVT
                     LGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQMGSWVAAGLTIPVGKIYFAFNPRLCL
                     EHIYQLEEVTGTRGRQSKAEINPRTNGDRAA"
     mat_peptide     477..1842
                     /product="insulin receptor-related receptor-alpha subunit"
                     /codon_start=1
                     /partial
     exon            484..1035
                     /number=2
     misc_feature    537..545
                     /note="potential N-linked glycosylation site"
                     /note="putative"
     misc_feature    924..1382
                     /note="Cys-rich region"
     exon            1036..1339
                     /number=3
     misc_feature    1329..1337
                     /note="potential N-linked glycosylation site"
                     /note="putative"
     exon            1340..1482
                     /number=4
     exon            1483..1627
                     /number=5
     exon            1628..1842
                     /number=6
     misc_feature    1629..1637
                     /note="potential N-linked glycosylation site"
                     /note="putative"
     variation       replace(1671,"t")
                     /note="substitution present in genomic clone,
                     Sprague-Dawley strain"
     variation       1760..1842
                     /note="genomic sequence, Sprague-Dawley strain"
BASE COUNT      334 a    566 c    504 g    438 t
ORIGIN
        1 cagggtggag tcctgcgtgt ctccggaccc tgctgccgcc cccccccggg gcactcccgg
       61 gggcgctccc agggcttcca ctctgtcttc cctcctgact gtctcacctc tggatctttg
      121 cgttcagaat cctaggtcaa tttctccctt tggatgcctc tctgaggctt cccctctcct
      181 gtctgcatct ctgttctctg gatcacactg aagctgtctc cagctgccgt cacaggcttt
      241 gtttcctctg atctgaaatt cttttctatc tcccactgtc tctacttgag atttctaatc
      301 cctttgctct tgtgtacccc ttccacactg gaacctgggt ctgactgcat cctcctttct
      361 tcctggagga tacctagaag acaatcaggg ctgaggtcat ggcagtgcct gctctgtggc
      421 cctggggagt atacttgctt atgagcctgc tgtccttggg atcttgcctg gacacactgg
      481 aggtgtgccc cagtcttgac atccgctcgg aggtgacaga gctccgtcgg ctggagaact
      541 gcagtgtggt ggagggtcac ctacagatcc tcctcatgtt tgccgccacg ggagaggact
      601 tccgaggcct cagctttcct cgcctcaccc aggtgactga ctacctgctg ctgttccgag
      661 tctatggcct agagagcctt cgagacctct tccccaacct tgctgtgatc cgaggtgcgc
      721 gcctcttcct gggctatgca cttataatct tcgagatgcc ccacttgagg gacattgggc
      781 tgccgtcact tggggccgtg ctgcgtgggg ccgttcgtgt ggagaagaac caggaacttt
      841 gccatctctc caccattgac tggggcctgc tgcagcctgc acctggtgcc aaccacattg
      901 ttgggaacaa gctgggtgag gagtgtgctg acgtgtgccc tggtgtgctg ggggctgctg
      961 gtgagccctg tgtgagaacc accttcggtg ggcacaccga ctacaggtgt tggacctcca
     1021 gccactgtca gagagtgtgt ccctgccccc gtgggctggc ctgcacagta ggtggcgagt
     1081 gctgccacag tgaatgtctc gggggctgca gtcagcctga agaccctcga gcctgcgtag
     1141 cttgccgcca cctctacttc caaggagtct gcctccccgc ctgccctccg ggcacctacc
     1201 agtatgagtc ttggcggtgt gtcactgcgg agctctgtgg ccatctgcga gaggttcctg
     1261 gacatgccac cgcctttggc atctacgagg gcagctgcct agctcagtgc cctccaggct
     1321 tcacccgtaa tggcagcagc attttctgcc ataagtgtga gggcctgtgc cccaaagagt
     1381 gcaaggttgg gacaaagacc atcgactctg tccaagccac acaggaccta gtgggctgca
     1441 cccatgtgga ggggagcctc atcctcaacc ttcgacaagg ctacaatctg gagccagagc
     1501 ttcaacgcaa cctggggctg gtggagacca tcaccggctt cctcaaaatc aagcactctt
     1561 ttgcactcgt gaccctggga tttttcaaga acctcaaact aatccgggga gattccatgg
     1621 tggatgggaa ctacactctg tacgtgttag acaaccagaa cctgcaacag atggggtctt
     1681 gggtggccgc agggctcacc attcccgtgg gcaaaatata cttcgccttc aacccacgcc
     1741 tctgcctgga gcacatatac caactggaag aggtgaccgg aaccagaggc cggcaaagca
     1801 aggctgaaat caacccccgg accaatggag atcgtgctgc ct
//