From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Xenopus laevis mRNA fragment for IgM VH-region (J2)
Date: 22 Dec 92 22:47:46 GMT
Distribution: bionet
Checksum: 35075 3

LOCUS       XELIMVJ2      425 bp ss-mRNA            VRT       23-NOV-1992
DEFINITION  Xenopus laevis mRNA fragment for IgM VH-region (J2)
ACCESSION   X14920 M37532 M37538 X12551
KEYWORDS    complementarity determining region; constant region.
SOURCE      Xenopus laevis RNA.
  ORGANISM  Xenopus laevis
            Eukaryota; Animalia; Chordata; Vertebrata; Amphibia; Lissamphibia;
            Anura; Archeobatrachia; Pipoidea; Pipidae; Xenopodinae.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Schwager,J., Grossberger,D. and Du Pasquier,L.
  TITLE     Organisation and rearrangement of immunoglobulin M genes in the
            amphibian Xenopus
  JOURNAL   EMBO J. 7, 2409-2415 (1988)
  STANDARD  full automatic
COMMENT     *source: tissue=blood; cell type=erythrocyte; library=lambda EMBL3;
            Clone=J2;
               From EMBL 27   entry XLIMVJ2;  dated 29-JAN-1990.
FEATURES             Location/Qualifiers
     misc_feature    68..154
                     /note="FR1 region"
     misc_feature    155..169
                     /note="CDR1 region"
     misc_feature    170..211
                     /note="FR2 region"
     misc_feature    212..259
                     /note="CDR2 region"
     misc_feature    260..354
                     /note="FR3 region"
     misc_feature    355..379
                     /note="CDR3 region"
     misc_feature    380..412
                     /note="FR4 region"
     CDS             14..>424
                     /note="(AA -18 to 119)"
                     /note="pre-IgM VH-region"
                     /codon_start=1
                     /translation="MKLFLVILLSLLSGGHCDVQFDESESVVIKPGGSHKLSCTASGF
                     KFSTTWMYWVRQAPGKGLQWVSRIYDGSNIHYVDSVKGRFTISKDNNNNKLYLQMNNL
                     QTEDTAVYYCVSEINVHFDYWGQGTMVTVTSVTAS"
     CDS             14..64
                     /note="(AA -18 to -1)"
                     /partial
                     /note="signal peptide"
                     /codon_start=1
                     /translation="MKLFLVILLSLLSGGHC"
     CDS             68..425
                     /note="(AA 1 - 119)"
                     /partial
                     /note="IgM VH-region"
                     /codon_start=1
                     /translation="VQFDESESVVIKPGGSHKLSCTASGFKFSTTWMYWVRQAPGKGL
                     QWVSRIYDGSNIHYVDSVKGRFTISKDNNNNKLYLQMNNLQTEDTAVYYCVSEINVHF
                     DYWGQGTMVTVTSVTAS"
BASE COUNT      124 a     80 c     98 g    123 t
ORIGIN      
        1 ccggactgtc aatatgaagt tgtttcttgt tattttattg tcacttttgt caggaggtca
       61 ctgtgatgtg caatttgatg agtcagagtc agtggtaata aagccgggag ggtctcacaa
      121 actgtcctgc acagcctctg gctttaaatt cagtaccacc tggatgtact gggttagaca
      181 ggctcctggg aaaggattac agtgggtgtc tcgtatatat gatggaagta acatacacta
      241 tgttgattca gttaaaggaa gattcaccat ctccaaagac aataataaca acaagttata
      301 tctgcaaatg aacaatctac aaactgaaga cactgctgtg tattactgtg ttagtgagat
      361 aaacgtccac tttgactatt ggggacaagg gaccatggtc accgtcactt cagttacagc
      421 atcgg
//