From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus Hexa mRNA for beta-N-acetylhexosaminidase
Date: 4 Sep 92 10:04:42 GMT
Distribution: bionet
Checksum: 12769     5

LOCUS       MUSHEXA      1810 bp ss-RNA             ROD       04-SEP-1992
DEFINITION  M.musculus Hexa mRNA for beta-N-acetylhexosaminidase
ACCESSION   X64331
KEYWORDS    Hexa gene; Tay-Sachs disease; beta-N-acetylhexosaminidase;
            ganglioside GM2 binding; glycosidase; lysosomal.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1810)
  AUTHORS   Beccari,T., Hoade,J., Orlacchio,A. and Stirling,J.L.
  TITLE     Cloning and sequence analysis of a cDNA encoding the alpha-subunit
            of mouse beta-N-Acetylhexosaminidase and comparison with the human
            enzyme
  JOURNAL   Biochem. J. 285, 593-596 (1992)
  STANDARD  full automatic
COMMENT     *source: clone_library=testis cDNA in lambda Zap;
            From EMBL    entry MMHEXA;  dated 05-AUG-1992.
FEATURES             Location/Qualifiers
     CDS             1..1587
                     /EC_number="3.2.1.52"
                     /product="beta-N-acetylhexosaminidase"
                     /gene="Hexa"
                     /codon_start=1
                     /translation="MAGCRLWVSLLLAAALACLATALWPWPQYIQTYHRRYTLYPNNF
                     QFRYHVSSAAQGGCVVLDEAFRRYRNLLFGSGSWPRPSFSNKQQTLGKNILVVSVVTA
                     ECNEFPNLESVENYTLTINDDQCLLASETVWGALRGLETFSQLVWKSAEGTFFINKTK
                     IKDFPRFPHRGVLLDTSRHYLPLSSILDTLDVMAYNKFNVFHWHLVDDSSFPYESFTF
                     PELTRKGSFNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGAPGLLTP
                     CYSGSHLSGTFGPVNPSLNSTYDFMSTLFLEISSVFPDFYLHLGGDEVDFTCWKSNPN
                     IQAFMKKKGFTDFKQLESFYIQTLLDIVSDYDKGYVVWQEVFDNKVKVRPDTIIQVWR
                     EEMPVEYMLEMQDITRAGFRALLSAPWYLNRVKYGPDWKDMYKVEPLAFHGTPEQKAL
                     VIGGEACMWGEYVDSTNLVPRLWPRAGAVAERLWSSNLTTNIDFAFKRLSHFRCELVR
                     RGIQAQPISVGYCEQEFEQT"
BASE COUNT      398 a    487 c    489 g    436 t
ORIGIN
        1 atggccggct gcaggctctg ggtttcgctg ctgctggcgg cggcgttggc ttgcttggcc
       61 acggcactgt ggccgtggcc ccagtacatc caaacctacc accggcgcta caccctgtac
      121 cccaacaact tccagttccg gtaccatgtc agttcggccg cgcagggcgg ctgcgtcgtc
      181 ctcgacgagg cctttcgacg ctaccgtaac ctgctcttcg gttccggctc ttggccccga
      241 cccagcttct caaataaaca gcaaacgttg gggaagaaca ttctggtggt ctccgtcgtc
      301 acagctgaat gtaatgaatt tcctaatttg gagtcggtag aaaattacac cctaaccatt
      361 aatgatgacc agtgtttact cgcctctgag actgtctggg gcgctctccg aggtctggag
      421 actttcagtc agcttgtttg gaaatcagct gagggcacgt tctttatcaa caagacaaag
      481 attaaagact ttcctcgatt ccctcaccgg ggcgtactgc tggatacatc tcgccattac
      541 ctgccattgt ctagcatcct ggatacactg gatgtcatgg catacaataa attcaacgtg
      601 ttccactggc acttggtgga cgactcttcc ttcccatatg agagcttcac tttcccagag
      661 ctcaccagaa aggggtcctt caaccctgtc actcacatct acacagcaca ggatgtgaag
      721 gaggtcattg aatacgcaag gcttcggggt atccgtgtgc tggcagaatt tgacactcct
      781 ggccacactt tgtcctgggg gccaggtgcc cctgggttat taacaccttg ctactctggg
      841 tctcatctct ctggcacatt tggaccggtg aaccccagtc tcaacagcac ctatgacttc
      901 atgagcacac tcttcctgga gatcagctca gtcttcccgg acttttatct ccacctggga
      961 ggggatgaag tcgacttcac ctgctggaag tccaacccca acatccaggc cttcatgaag
     1021 aaaaagggct ttactgactt caagcagctg gagtccttct acatccagac gctgctggac
     1081 atcgtctctg attatgacaa gggctatgtg gtgtggcagg aggtatttga taataaagtg
     1141 aaggttcggc cagatacaat catacaggtg tggcgggaag aaatgccagt agagtacatg
     1201 ttggagatgc aagatatcac cagggctggc ttccgggccc tgctgtctgc tccctggtac
     1261 ctgaaccgtg taaagtatgg ccctgactgg aaggacatgt acaaagtgga gcccctggca
     1321 tttcatggta cgcctgaaca gaaggctctg gtcattggag gggaggcctg tatgtgggga
     1381 gagtatgtgg acagcaccaa cctggtcccc agactctggc ccagagcggg tgccgtcgct
     1441 gagagactgt ggagcagtaa cctgacaact aatatagact ttgcctttaa acgtttgtcg
     1501 catttccgtt gtgagctggt gaggagagga atccaggccc agcccatcag tgtaggctac
     1561 tgtgagcagg agtttgagca gacttgagcc accagcgctg aacacccagg aggttgctgt
     1621 cctttgagtc agctgcgctg agcacccagg agggtgctgg ccttaagaga gcaggtcccg
     1681 gggcagggct aatctttcac tgcctcccgg ccaggggaga gcaccccttg cccgtgtgcc
     1741 cctgtgacta cagagaagga ggctggtgct ggcactggtg ttcaataaag atctatgtgg
     1801 cattttctct
//