From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse P-cadherin gene, exon 1 and 2.
Date: 5 Jan 93 06:48:17 GMT
Distribution: bionet
Checksum: 63816 17

LOCUS       MUSPCADHE   11473 bp ds-DNA             ROD       05-JAN-1993
DEFINITION  Mouse P-cadherin gene, exon 1 and 2.
ACCESSION   D12688
KEYWORDS    adherens junction; calcium dependent; cell adhesion;
            transmembrane protein.
SOURCE      Mus musculus (strain C57BL6) (library: EMBL4) DNA, clone PG102.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Mammalia; Rodentia; Muridae.
REFERENCE   1  (sites)
  AUTHORS   Nose,A., Nagafuchi,A. and Takeichi,M.
  TITLE     Isolation of placental cadherin cDNA: identification of a novel
            gene family of cell-cell adhesion molecules
  JOURNAL   EMBO J. 6, 3655-3661 (1987)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Hatta,M., Miyatani,S., Copeland,N.G., Gilbert,D.J., Jenkins,N.A.
            and Takeichi,M.
  TITLE     Genomic organization and chromosomal mapping of the mouse
            P-cadherin gene
  JOURNAL   Nucleic Acids Res. 19, 4437-4441 (1991)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 11473)
  AUTHORS   Hatta,M. and Takeichi,M.
  TITLE     Complex cell type-specific transcriptional regulation by the
            promoter and an intron of the mouse P-cadherin gene
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     Submitted (22-JUL-1992) to DDBJ by: Masatoshi Takeichi Dept. of
            Biophisics, Faculty of Science Kyoto University Kitashirakawa,
            Sakyo-ku Kyoto 606-01 Japan Phone:  075-753-4196 Fax:
            075-753-4197
               Sequence updated (20-NOV-1992) by: Masayuki Hatta.
FEATURES             Location/Qualifiers
     repeat_unit     2472..2674
                     /note="B1 repeat"
     repeat_unit     4160..4262
                     /note="B1 repeat"
     repeat_unit     9766..10120
                     /note="B2 repeat"
     exon            10161..11047
                     /number=1
     exon            11263..11380
                     /number=2
     CDS             join(11000..11047,11263..11380)
                     /partial
                     /codon_start=1
                     /translation="MELLSGPHAFLLLLLQVCWLRSVVSEPYRAGFIGEAGVTLEVEG
                     TDLEPSQVLGK"
BASE COUNT     3112 a   2744 c   2779 g   2838 t
ORIGIN      Chromosome 8.
        1 gaattccaag tctctattgc ttccagtgag atctgaggtc ttgtgagtgc tttattgatt
       61 ccttgccata agcattctta gcttctggtc tctggaaggt aataattgct caggccttgg
      121 caggcattca ctcagccctg aagtcagctc tgcttcactc acgattcaga gaaagaggaa
      181 gcaaagcaaa agggatttct caatggacgc agatgtgttg tctcagcacc tctgagaact
      241 cgaagcagaa atgttgagta ctgaccagtg atgtcacaca gcaaaaaagg aggctcccag
      301 gaaattcagg aagagactca aagaagaaag atgatgaaat agtttgtgac aagcccaggg
      361 tggatcatgc ccagaaacgg cttcacccag ttttaaggcc gcttcctgga aggctgggaa
      421 acatcctgtg gtctttgaga tctccccata actgggttct gggggagtag agcgctggga
      481 gttttacgac caaaaatggg aagaaagtct cagtctaaat atttctcagg aggcccagag
      541 tttaaccttg aaccaaggtc aaatatgttt attttgtaga gattcttggg ggtggagggg
      601 agaattgtgg attggaatgg agctccttct gttgctaaat cccttgtctg ttgtctacaa
      661 ggccctggct tccatcttca gccaaacaga aaagtcgcca agattgaggt attatttctc
      721 atgtacaaag catgttctcc aagtccattc tagaaaatgc ttttcaagag caggttggca
      781 ataaatctgg gagtccagag ctgggtacag cacaggttca cgtcttcctt gctgtttggc
      841 cttggacagg ggacagaacc ttttacttgt aagacataaa accaggacaa gcagggctat
      901 acagagaaac cctgataagg agagagagag agagagagag agggagagag agaaagagag
      961 agagagagag ggaggaatct tatgaactac ctcctagaac tgcatggatt agaagaatta
     1021 agctcgcaca ggaaagcaca tggccgcaag tctggtatgc agtgattaat acggaattgt
     1081 ggttatttgt cttcttatga agcgtgtgat ttgtatggca ctttgcagaa agactcttcc
     1141 ctcacatgag tgcactggag cgctgctgtg tgaggtcggt cagggaaaca acattgattt
     1201 tgcttctcct gtgcatttag caccctgcca gatgctaaca gatagtgttt tgttggtttc
     1261 acttattcaa taaatatttg agtatttgat gccaggttgt tttaggcact ggggaatcta
     1321 gcagtgaacg aaatagatta ataaaaaaaa aaagatcctt gactggggat ggagagatgg
     1381 ctaaggaggt gaagccactg agaatctgag cttggattcc cccaacacct acctgaaagt
     1441 catgtgtggc aacactcgtc tgtaacctta acagacagaa agacagacac cccaccacta
     1501 ccacctcacc cccagagctt ttgggcaagc caacagtgct ctatcagtga tctctgggtt
     1561 caatcttctc ataaagaatg aagtggaaag ccaagtgaag aaggcacctg ccatggacct
     1621 cttcagtcct atgcaaggcg agagtggagc aggctctaga cctttgcatt aaatgactcc
     1681 atgatggaag caccactcag cacatagaca gcaccacctg ccaaacaaaa acaaggccct
     1741 aatccaccaa agtctagagt tcaggaaaag tctctaagtg gactggcctg gcttgttagc
     1801 tcctggagct ccccttctgg ctaactgtct ttgttaactg aagtatgtca agcacaagtg
     1861 gtttttccac gtaaaagctc accccaagaa atgtttagtg tcaccctggg gtctcaaata
     1921 cgcagggtgg tcaccagctg gcccctaaaa aattcctgta aattcagttc catggggggg
     1981 gggggttcta tacccctttt gctcccaaat aactgcaggc gttctacact ctgctccagc
     2041 ccattttagc tcctggatat tggacacaga gagctggcat ttgtattaac aagctgtaaa
     2101 cctaagcagg acaggttctg aactattcta gcccaactag gatattaata cttagataaa
     2161 tgtcccatta cttgccatct ggtcttgccc tggctctctt gtcatgagct cattgtgaat
     2221 cccttggtgg cctgctcatc actactcctc ctagacctgc ctcatagcta cctcttctct
     2281 ttcctcctca ccctacttct ttctgtctgg gaccatagtc tgggaccaaa agttttcctc
     2341 tgccccagtc aaaggctgag tcaacccttt gttgaccaac tgtaaggtgg tggagaagaa
     2401 tatttacaaa acacctagac agtaaatgct tcataaaaat aacaatacca ccaggtgttg
     2461 tggtggcctt taagcccagc acttgggagg caaaggcagg cagatttctg atttctggtc
     2521 tacagagtga gttccaggac agccagggct atacagagaa accctgtctc aaaaaacaaa
     2581 caaacaaaca aacaaacaaa caaacaaaca aagtcagtgg cactcaactc tttgtgggta
     2641 tggaaatcag catttgaata atacaaagac aacctttaca cactgcacaa agagactatc
     2701 cctacacttt cccttacttg cagctgtctg agcagtcttc tctggtggat acctcgcaac
     2761 aagagcacac ccacacaaga acatacacat atgtacactc atccatacac cacacacaca
     2821 cacacacaca cacacacaca cacacacaca cacaaataaa aaccagtaat taaaagatgt
     2881 tcattagggg ttggaaagat ttggttggag agcactgggt gttcttccag ggcacccaca
     2941 tgtcagctca ctgtcatctg tcactccagt catctgtcac tccagtcatc tgtcactcca
     3001 gtcatctgtc actctagtcg tctgtcactc cagtcatctg tcacttcagt catctgtcat
     3061 tccagttgtc tgtcactcca gtcatctgtc attccagttc ttaatacgtt ctcacgcccg
     3121 gccaggaaag acgcaacaaa ccaaaatctt ctgcggcaaa actttattgc ttacatcttt
     3181 gggagccagg aggcaacgcc cagcgcccag ccccaaaaac gaaagcccct tcaataatga
     3241 aaccgaaacc ccttccctat ttaggagagt tatatttcgc ctaggcgcat cactccctga
     3301 ttgctgcagc ccatggccga gctgacgttc acgggaaagg cagagtacaa gtagtcgtaa
     3361 aatacccttg gcacatgcgc agattatttg tttaccactt agaacaaagg atgtcacgcc
     3421 atcttgtgac ggcgaatgtg ggggcggctc ccaacatcca gtcatctgtc actccagtca
     3481 tctgtcgctc actccagtaa tctgtcactc caggcgtctg ttactctagt cgtctgtcac
     3541 tccagtcatc tgtcacttca gtcatctgtc attgcagttg tctgtcactc caggcctctg
     3601 tcactccagt ttcaaggatc tggagctttc tctgacctcc atgggcacca gacactcaca
     3661 catgcatgca ggcaaaacac tcacagacat aaaataattg aagtgtttaa aaaagatatt
     3721 ctttagtacc tcttctgatt actcaactgc aagttgatta aaccagtttt ttgtttgttt
     3781 gtttgttttt aaaaaatcct ttctcacata gggagttctt ccacctggag aaagacagta
     3841 agcagcagat actgatcttt taggtttgat gtcacacggt accttacaaa catgcattgt
     3901 gcagatgact tttgagacac atggtcactt actcagagtc ttgtggctaa gttgagctaa
     3961 attcagattt aaagccagat agcacgattc tgagttctga atcctgatca ctatggtctg
     4021 gtaccttccc caacaaaacc agcatcaaag cagacaaaca ctttatcatt tttgtttgtt
     4081 tgttttggtg tttgtgacag ggtcttctta tagctctggc tgtcctggaa ctactacata
     4141 gacttagacc aaggaacacg cctttaatcc cagcactcag aaggcagaaa caggctcaag
     4201 atcagtctgg tctacagaaa ttctaggcca tagaggactg catagtaaga ctctgtctca
     4261 aagtagtagt agtagaagta atagtaataa gaataagtat aattggagaa tagggtgtgt
     4321 gtgttctcca tgcagagtca tcagggagca gctctttgag gactcacctc tagagaccct
     4381 ccaggcatgg gaaaggctcc aagggatatc ttggaacatc agtcctggca gagggaagag
     4441 tctgtgcaaa ggccggaaac ggaccgctcc caacgttcca gggagtcaca tggacaccag
     4501 tacagaagat gccgtgagcc aaggctcaca gatggctcac ccaagctgcg ggcaggatgc
     4561 agctgtttct tgctgcggag gattatggga gcaggtttgc atggcaaggt gaggagttgg
     4621 tttttggtaa catccaagtg ggaatgacca gctccagagg atgtaaaggg ttagtagata
     4681 acccaggcag gcagtcatct tccacagctt gattcaaacc caagtaaatg agtgtggtgg
     4741 tacccacctc taatccctgc actgaggcag aaggatcagg agttcagggc cagcctgact
     4801 tacataatca aggttgagat cagccaaagg ttgaggacag taaaaacaag gactgaagat
     4861 agaacatgcc caggctttca tccttaatat cacataagct gggaatagtg gaatcctagc
     4921 atctggggag acagaaggtc tgcaagttct aggacaccct ctactattag tgagttctga
     4981 gccagcctgg gctacataaa atactatcta aaaaaataag ggatggagtg gtgggaatat
     5041 ggttcatcgg caaaagtgct tttaatacaa gcaaaagaac cagcgtccag atcgtgtgaa
     5101 ctcctataaa tgcgtggtga gtatggtggc tcacctgtca ttctgtcttg gaaggtggaa
     5161 acatggggtc ccccaaaaga acctggctgg tgaaagtagc tatattgata agctctgggt
     5221 ttgatgagaa accctgcctc aaagaataag gtagaagagt catagaagat ttctgaatga
     5281 aaaactgcct cgaacctcca tctgcataca tttgtgtgtt tgcacctgcc tgctacatgc
     5341 actgggggcg cgcgcggggc gcgcacacac acacacacac acacacacac acacacgggc
     5401 gtgcgagcat gggggagtgg agggagacag agagtgagag agagagagag agagagagag
     5461 agagagagag agagagagac acctcagctc ttggtctgtg ggctttacat tttaaagcac
     5521 atacactacc ccgtgtgggt gtgggtaagt ctggagctgt tcaattccga caggcttagc
     5581 ctctgtcccc aaggagggtt taaggtggga ggaaaggggg agaaagatag cagagagtct
     5641 agcaactgag acactgagcg gaaagcagag gcaccagaga ttttttacag cacagtaaaa
     5701 ggcaaacatt taaatacaaa atgcagtcaa ggaacgctga gaaggggctg ttttctggaa
     5761 aggaaaaagg aagagttcca gccccgtgga cctggaggat gtccaacaga ctgtgcgctg
     5821 ttggaaatgg tattacagtt tggatctttg tctcccaaag tggtctgggg aaatagttca
     5881 gtggtgcagt gcctggcaca cacaaagccc cgggttttat ccccagactt ccctgtaccc
     5941 caaagtctcc aaagattggt cttcaaggtc cactaatggg aaatgatgag tatttaagag
     6001 ctgggggctg gggataggta cagtggcgca ctccttgaga gagacaggca gatctctgtg
     6061 catttgaggt tacctgatgt agagttccag aacaacatag gcttagtgaa atcatctttc
     6121 caaaaaactc acacataaac acacacacaa aaaaaatgta ggacccggtg atcattggga
     6181 acacattctt atattttgtt atttagtatt tgacctgtta atgctacaaa ttttaatttt
     6241 tttaaaattc cttttatgca tctgagtatt ttgtctgcat atacattttg tgcatgtctg
     6301 gagaagccag aagtgggcct cagattccct ggaactggag ttaagaatgc ctgtaagcag
     6361 ccatgtgggt gcctggaaca aacccagtta acattttttc tgtaagaaca gtgagtgctc
     6421 ctcaccctga gtcatctctc tagcccaaaa tcagtttgtt tgattgtttt taccttttaa
     6481 aactttattt tctgtgtatg tttgtccaca tgtgtatatg agctccactt atgttcctgg
     6541 tgcctgagga ggccaagaaa gggcatccaa ttctagaaat gaagttacag agggggttat
     6601 gagccaccat gtggtgctca gaacctgggt cccctacaag agctacagtg ctctgaactg
     6661 ctgaactatc tcaccagccc ctggactttt gtttcctaaa gttaactttt agggcaatct
     6721 tatgcattgt attttgatta cattgacaca cacacacaca cacacacaca cacacacaca
     6781 cacacacaca cacctgcatt atttcttgac cccctctcaa tcacacccca tcttctgcac
     6841 cactaagaaa agtgtctccc catgccatgg ggacatgttc tgaagcttga tgcctcttct
     6901 tcttccattc tttgtttcca aggttaccag gaggtaggtg ggttttgcgc aataaacctc
     6961 tgccaccata tgctgctatc acaggcccaa tactttgggg tctctcagct gtggactgga
     7021 acctccaaaa ctccaaacaa acctttctct ttctcacttg catgtctctg gcatttttct
     7081 ttatttgtta cagaaaactg actaatagag atgtgaaggc tccaggaacc cagggtccaa
     7141 cctcggcaag cctgccttcc actgtaaggt gccagactcc gcgtgttgcc tttgtgacag
     7201 agcacatccc ccagccacat tggtcttctg cggtggcaca tacaacaact acagcctcct
     7261 catcacacca tggcaggctt ctgacacatc ccaaacagaa gaagctcttg gtccgtcttc
     7321 agttccaagc ttgttctgga ttcatgtccc cagcaagaca catcaagaag tgctcccagg
     7381 aagaactgtt aactaaacgg gagaccgcag ctgaagggca gcggcggtgt gagtacagac
     7441 ctagtcccaa agagagcatc agccagatgt acaggggaac tctggtgcaa ttacaactta
     7501 gcgtttgtct gtttggaaag gaaggatgct ggggctgtca cctacaccag gtaatcactg
     7561 gctgtgggtg gaggaagcaa attctgggca tctgttttgt ttttccaaga caagagcttg
     7621 gagatacaca cacacacaca tacacacaca cacacacaca cacacacaca cacacacaca
     7681 tcccacgctg accttgaact catgatcagg ctatccggga aatttaactg aaactcaaga
     7741 ctgagattca tttagttaaa tgcatgaatt gatgaatgac cagctggaga atgcgcagaa
     7801 ggcagcgtcg tggtccaggc tcgcccgaag agctgagtat cgttttctcc gctctgctcg
     7861 cggccccccg ccggaatgca gagtgccctg gaaggaggcg gaaatgagcg cgctcacagc
     7921 tctccagccg agtgtttact taattagggc ctgtatcctg aggctcgttt gtgtttaact
     7981 gtctgcctaa tggtttcgtc tggctccggg ccggcgctgg gggaactttg ggggtgagga
     8041 taggtcgagc caccctgtcc cctctaggtt agagcattga gcagctccag cgtgcagcta
     8101 ggatttggca agcgtcccca gcaggagagc tggaccacta agctgccttg ggctttttct
     8161 gcagttgcca cctcctccca cagtgctagg actgcgcgga tcactgaaga ctccagagat
     8221 ggcagatgcc ggctgcccgc agcggcgaaa ttgaaggatt ctgacactgc tcattctctt
     8281 agttgtggaa ctgggagcgc tagcagttcc ctagctggcg aggcagagaa aactaaatga
     8341 gccgcatcct agagtcctaa taccgacacc actgggctct tgctcagtgc cagctactga
     8401 gttcagcgtt tttaacacgt tcatctgttt aatcctcaag tacacatctt cgtttaattc
     8461 taatacagcc gagctcctct tcctaccccc cccctctgtg tgtgtgtgtg tgtgtgtaag
     8521 agagagggag agggagagat gtgtgttcat gagtatgagt aggggccacg tgcattggcc
     8581 agaggacagt ctctgagaca atactatctt tcaccttgtt tgagattggg tctctttgtt
     8641 tgacactgta tgaaccaggc tggctggcct gctggcttcc ttctgccctc ccccccatct
     8701 cttcatagga gatccttaca gatgggctac tgccatccac attccgtgga atctggggac
     8761 ttgaacttgg gacttaccaa agcacattat ccactgagcc ttctccttta gtctagtcct
     8821 ttttttttga aacaaagact cactatgtag tgtaggttgt ctttgaactt gcagtaatca
     8881 tcttgcctcc acaccccgag cagggattaa aggcacaccc ctctcctggc tctagtacag
     8941 tactttcaga gggtaggtat caaaataatc ccagtgacag ctgaatagcc tcagtaagag
     9001 gtgggacccg agtctaaatc ccacacagta aatcgagtag agccaatgct tgcctgatta
     9061 catcataagt ctactgctca gcagagactt gggtagaagg cagtaggtac aggttaatac
     9121 ttgaaggcaa acaaaacaaa acaaacataa acttctaaag ctgagctagc tggagaaaaa
     9181 gcatcatcct gggattctct ggagagcaat gcaagatgag gcgcactcgg agaatggggg
     9241 tggggggata cgttggttca gaaggcttgt ctcatccagg gctgaggctg cagctcagca
     9301 gtggagcact tacttgcctg gcaggtgtgc aaggtcatgc gttcaatctc cagcattgca
     9361 gagaggaggg gcaggggatg ggggagagat gcctttacag ggaaagggca cggggaatgg
     9421 ggccgttgga acctgtgcat ggggtggcaa gtcttagtac taggtacaag gtcttagtac
     9481 taggaaggta gaggcaggag aatcggaagt tcaaggccat cccaggtgca tagtttcagg
     9541 ccagcctgag acacattaca ctttttttaa aaagtcatca ttgttaagct ggtcattgtg
     9601 ggtcattgtc ttttattcca gcagttagga gccagagaca gaaggtttga atgaattcaa
     9661 ggccagcctg agactacaat gtgagagtct gcctcaaaac aaaagaaaaa aaaaaaaaaa
     9721 ccacacaaac aagcaaacac aaaaaacgga caaaggagat ggtttagcag gtaaagcaca
     9781 ctggagaaat ggctcagagg ttaagaacac tggctgctct tgcagaggtc ctgagttcaa
     9841 ttcccagcaa ccacatggtg gctcacaacc atctgtaatg ggatctgatg ccctcttctg
     9901 gtgtgtctga agacagcgac agtgtactca cataaaataa ataaatacat aaataagtgt
     9961 taaaaaaaaa agtttgggcc cagcaggtaa tgcacaatcc taacgacctg agttcaatcc
    10021 cagaatccat ttaaaggagg aaggcgagaa ccaactccac aaagtcgtcc tctgaccttc
    10081 acatgtgtgc gatgggccat tcatacatga caataataaa taacgcaaaa atctccattg
    10141 tttgcattta acataaaatt aaggaaacaa ttatatttgg agaaagaaaa catttatatt
    10201 gggggtgcca gaaataatgg ggctgataac aaatagcttg tgccctacct caagcccttt
    10261 gaagttacta tggcttccaa actctgggac tttctgtact agctgccttc catttgtcca
    10321 gctgcaaacg gaagttacta ttctctcaca cgtgtatcag atcgcgtagc ggtcctttga
    10381 gacctcgatg ccacttttaa aacccgggac gcgctccccc gcccccgccc ctgcccctcc
    10441 ccggcctagt gtgggaggta gagaaagtgg cagagggcag acccctctgt agcgggtgta
    10501 aagacacgcc ctgccttcat caaagctttg aacacagcgc ctccggtagc atgaatgggg
    10561 agcctctgtt tttttgtcgg gtttcagatg cgtctccact ttttttccgt tgtagctgcc
    10621 agcaatggaa tatttgtctt cccgtgctgc agaggctgag gtggagtgga ttggggggtt
    10681 ttgttttgtt agattatttt ccatcgaagc cagagactgc gagagcaacg gggtaccttt
    10741 cagaagtagt tccagaagag cagggaggcc ggtggagggc accagggagg acctttaggg
    10801 cttcgaggac tgtcggcagg ctggcctcga ccccacctgc gagggggcgg gaccttgtga
    10861 cgttggacca atcagcagct acctgagcgc acctggcctc ctcccgcggg ctccagcgag
    10921 ccgcggtgct caaagctgca cccggagctt agcacgagcg cgccccaccg tcgcggcacc
    10981 ttctcacctc ccttcagtta tggagcttct tagtgggcct cacgccttcc tgctcctcct
    11041 gctccaggta ccacagtgct ttgccatggt cctgacccgg attgttccct ggagggcggg
    11101 tggggttctc acgctgcggg cgtcttttta atcttagggc tgtgctcctt ggggccaagg
    11161 ttgtcccgga gccccccccc caggactccc aagaatgggt gtacagaacc aggcatgcct
    11221 gtgactcagc ctcctcttta acccttctac cctcacactc aggtttgctg gctacgcagc
    11281 gtggtctccg agccctaccg agcgggcttc atcggggagg ctggagtgac cttggaggtg
    11341 gaaggaactg acctggagcc gagccaagtt ctggggaaag gtaagacccc tcccggagcc
    11401 agcctggatg gagccacagt gcggaagacc acacgtcttc gctttactgt ggcgcatcgg
    11461 aaggttgtct aga
//