From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human polymorphic epithelial mucin (PEM) mRNA, complete cds.
Date: 5 Nov 92 23:10:47 GMT
Distribution: bionet
Checksum: 34605 5

LOCUS       HUMMUCAB     1804 bp ss-mRNA            PRI       15-SEP-1990
DEFINITION  Human polymorphic epithelial mucin (PEM) mRNA, complete cds.
ACCESSION   J05581
KEYWORDS    polymorphic epithelial mucin.
SOURCE      Homo sapiens adult adenocarcinoma cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Gendler,S.J., Lancaster,C.A., Taylor-Papadimitriou,J., Duhig,T.,
            Peat,N., Burchell,J., Pemberton,L., Lalani,E.-N. and Wilson,D.
  TITLE     Molecular cloning and expression of the human tumour-associated
            polymorphic epithelial mucin, PEM
  JOURNAL   J. Biol. Chem. 265, 15286-15293 (1990)
  STANDARD  full automatic
COMMENT     Draft entry and computer-readable sequence for [J. Biol. Chem.
            (1990) In press] kindly submitted by S.J.Gendler, 26-JUN-1990.
FEATURES             Location/Qualifiers
     mRNA            <1..1804
                     /note="PEM mRNA"
     sig_peptide     73..135
                     /gene="MCNAA"
                     /codon_start=1
     mat_peptide     136..1497
                     /product="polymorphic epithelial mucin"
                     /gene="MCNAA"
                     /codon_start=1
     polyA_signal    1783..1788
                     /gene="MCNAA"
     CDS             73..1500
                     /gene="MCNAA"
                     /product="polymorphic epithelial mucin"
                     /codon_start=1
                     /translation="MTPGTQSPFFLLLLLTVLTVVTGSGHASSTPGGEKETSATQRSS
                     VPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVP
                     VTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTS
                     APDNRPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPSHH
                     SDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTSPQLSTGVSFFFLSFHISNLQFNS
                     SLEDPSTDYYQELQRDISEMFLQIYKQGGFLGLSNIKFRPGSVVVQLTLAFREGTINV
                     HDVETQFNQYKTEAASRYNLTISDVSVSDVPFPFSAQSGAGVPGWGIALLVLVCVLVA
                     LAIVYLIALAVCQCRRKNYGQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYE
                     KVSAGNGGSSLSYTNPAVAATSANL"
BASE COUNT      361 a    622 c    434 g    387 t
ORIGIN      
        1 cgctccacct ctcaagcagc cagcgcctgc ctgaatctgt tctgccccct ccccacccat
       61 ttcaccacca ccatgacacc gggcacccag tctcctttct tcctgctgct gctcctcaca
      121 gtgcttacag ttgttacagg ttctggtcat gcaagctcta ccccaggtgg agaaaaggag
      181 acttcggcta cccagagaag ttcagtgccc agctctactg agaagaatgc tgtgagtatg
      241 accagcagcg tactctccag ccacagcccc ggttcaggct cctccaccac tcagggacag
      301 gatgtcactc tggccccggc cacggaacca gcttcaggtt cagctgccac ctggggacag
      361 gatgtcacct cggtcccagt caccaggcca gccctgggct ccaccacccc gccagcccac
      421 gatgtcacct cagccccgga caacaagcca gccccgggct ccaccgcccc cccagcccac
      481 ggtgtcacct cggccccgga caccaggccg gccccgggct ccaccgcccc cccagcccat
      541 ggtgtcacct cggccccgga caacaggccc gccttgggct ccaccgcccc tccagtccac
      601 aatgtcacct cggcctcagg ctctgcatca ggctcagctt ctactctggt gcacaacggc
      661 acctctgcca gggctaccac aaccccagcc agcaagagca ctccattctc aattcccagc
      721 caccactctg atactcctac cacccttgcc agccatagca ccaagactga tgccagtagc
      781 actcaccata gcacggtacc tcctctcacc tcctccaatc acagcacttc tccccagttg
      841 tctactgggg tctctttctt tttcctgtct tttcacattt caaacctcca gtttaattcc
      901 tctctggaag atcccagcac cgactactac caagagctgc agagagacat ttctgaaatg
      961 tttttgcaga tttataaaca agggggtttt ctgggcctct ccaatattaa gttcaggcca
     1021 ggatctgtgg tggtacaatt gactctggcc ttccgagaag gtaccatcaa tgtccacgac
     1081 gtggagacac agttcaatca gtataaaacg gaagcagcct ctcgatataa cctgacgatc
     1141 tcagacgtca gcgtgagtga tgtgccattt cctttctctg cccagtctgg ggctggggtg
     1201 ccaggctggg gcatcgcgct gctggtgctg gtctgtgttc tggttgcgct ggccattgtc
     1261 tatctcattg ccttggctgt ctgtcagtgc cgccgaaaga actacgggca gctggacatc
     1321 tttccagccc gggataccta ccatcctatg agcgagtacc ccacctacca cacccatggg
     1381 cgctatgtgc cccctagcag taccgatcgt agcccctatg agaaggtttc tgcaggtaat
     1441 ggtggcagca gcctctctta cacaaaccca gcagtggcag ccacttctgc caacttgtag
     1501 gggcacgtcg cccgctgagc tgagtggcca gccagtgcca ttccactcca ctcaggttct
     1561 tcagggccag agcccctgca ccctgtttgg gctggtgagc tgggagttca ggtgggctgc
     1621 tcacaccgtc cttcagaggc cccaccaatt tctcggacac ttctcagtgt gtggaagctc
     1681 atgtgggccc ctgaggctca tgcctgggaa gtgttgtggt gggggctccc aggaggactg
     1741 gcccagagag ccctgagata gcggggatcc tgaactggac tgaataaaac gtggtctccc
     1801 actg
//