From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human Wilms tumor gene 1, exon 10
Date: 24 Jul 92 10:07:46 GMT
Distribution: bionet
Checksum: 27950     4

LOCUS       HUMWIGEX10   1863 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  Human Wilms tumor gene 1, exon 10
ACCESSION   X61638
KEYWORDS    Wilms' tumor; wt1 gene.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Gessler,M.
  JOURNAL   Unpublished (1991)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Gessler,M., Koeng,A. and Bruns,G.A.
  TITLE     the genomic organization and expression of the WT1 gene
  JOURNAL   Genomics 12, 807-813 (1992)
  STANDARD  full staff_review
COMMENT     *source: cell_type=human placental DNA; *source: clone_library=
            cosmid, pWE15; *source: clone=cLFT3, cLK, cLT; *source: chromosome=
            11p13;
            From EMBL    entry HSWIGEX10;  dated 22-MAY-1992.
FEATURES             Location/Qualifiers
     intron          1..227
                     /number=9
     exon            228..1623
                     /number=10
                     /gene="WT 1"
     misc_feature    228..346
                     /note="zinc finger 4 coding region"
     misc_feature    347..349
                     /note="stop codon"
     polyA_signal    1604..1609
BASE COUNT      508 a    360 c    417 g    578 t
ORIGIN
        1 tttctgacct aagaatataa ctttttacaa tatttcgatc cttaaagccc caagaggtgc
       61 tgctgtttca aggctgcctg ggaaatgagc tcagttggtt agctcaggga cagaatgatg
      121 ggaaattcag agtgggtgcc ttgtgatgac ttcactcggg ccttgatagt tgaacttgtg
      181 cctgtctctt tgttgcaagt gtctctgact ggcaattgtg tcaacaggtg aaaagccctt
      241 cagctgtcgg tggccaagtt gtcagaaaaa gtttgcccgg tcagatgaat tagtccgcca
      301 tcacaacatg catcagagaa acatgaccaa actccagctg gcgctttgag gggtctccct
      361 cggggaccgt tcagtgtccc aggcagcaca gtgtgtgaac tgctttcaag tctgactctc
      421 cactcctcct cactaaaaag gaaacttcag ttgatcttct tcatccaact tccaagacaa
      481 gataccggtg cttctggaaa ctaccaggtg tgcctggaag agttggtctc tgccctgcct
      541 acttttagtt gactcacagg ccctggagaa gcagctaaca atgtctggtt agttaaaagc
      601 ccattgccat ttggtctgga ttttctactg taagaagagc catagctgat catgtccccc
      661 tgacccttcc cttctttttt tatgctcgtt ttcgctgggg atggaattat tgtaccattt
      721 tctatcatgg aatatttata ggccagggca tgtgtatgtg tctgctaatg taaactttgt
      781 catggtttcc atttactaac agcaacagca agaaataaat cagagagcaa ggcatcgggg
      841 gtgaatcttg tctaacattc ccgaggtcag ccaggctgct aacctggaaa gcaggatgta
      901 gttctgccag gcaactttta aagctcatgc atttcaagca gctgaagaaa gaatcagaac
      961 taaccagtac ctctgtatag aaatctaaaa gaattttacc attcagttaa ttcaatgtga
     1021 acactggcac actgctctta agaaactatg aagatctgag atttttttgt gtatgttttt
     1081 gactcttttg agtggtaatc atatgtgtct ttatagatgt acatacctcc ttgcacaaat
     1141 ggaggggaat tcattttcat cactgggact gtccttagtg tataaaaacc atgctggtat
     1201 atggcttcaa gttgtaaaaa tgaaagtgac tttaaaagaa aataggggat ggtccaggat
     1261 ctccactgat aagactgttt ttaagtaact taaggacctt tgggtctaca agtatatgtg
     1321 aaaaaaatga gacttactgg gtgaggaaat ccattgttta aagatggtcg tgtgtgtgtg
     1381 tgtgtgtgtg tgtgtgttgt gttgtgtttt gttttttaag ggagggaatt tattatttac
     1441 cgttgcttga aattactgtg taaatatatg tctgataatg atttgctctt tgacaactaa
     1501 aattaggact gtataagtac tagatgcatc actgggtgtt gatcttacaa gatattgatg
     1561 ataacactta aaattgtaac ctgcattttt cactttgctc tcaattaaag tctattcaaa
     1621 aggaaagtgg caagattcca tcagctgtat tgtgttcaaa tctcaaggcc actgagcctc
     1681 ttttaaacag gtaagagaag acgccaccga catcgacggc tactagtgag cctatccagg
     1741 tcctgaccac aatttatttc tctctgtcaa acttcaggag ggacttatat gtcctagaag
     1801 caacagagaa tatcttcacc ttgtgttaca gagtgattgt gctcatgctg tggttgaatg
     1861 ggg
//