From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human alpha 2(V) type I collagen (COL5A2) gene, 5' end.
Date: 15 Sep 92 10:04:36 GMT
Distribution: bionet
Checksum: 52307     5

LOCUS       HUMCOL5A2A   1671 bp ds-DNA             PRI       15-SEP-1992
DEFINITION  Human alpha 2(V) type I collagen (COL5A2) gene, 5' end.
ACCESSION   M58529
KEYWORDS    extra-cellular matrix protein; type I collagen.
SOURCE      Homo sapiens (library: EMBL-3) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1671)
  AUTHORS   Greenspan,D.S., Lee,S.T., Lee,B.S., Hoffman,B.S. and Hoffman,G.G.
  TITLE     Homology between alpha-2(V) and alpha-1(III) collagen promoters and
            evidence for negatively acting elements in alpha-2(V) first intron
            and 5' flanking sequences
  JOURNAL   Gene Expression 1, 29-39 (1991)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     TATA_signal     1050..1055
                     /gene="COL5A2"
     exon            1082..1336
                     /number=1
                     /gene="COL5A2"
     CDS             1172..1186
                     /note="small upstream ORF"
                     /product="pro-alpha 2(V) collagen"
                     /gene="COL5A2"
                     /codon_start=1
                     /translation="MVLQ"
     CDS             1223..1237
                     /note="small upstream ORF"
                     /product="pro-alpha 2(V) collagen"
                     /gene="COL5A2"
                     /codon_start=1
                     /translation="MSNI"
     intron          1237..1671
                     /number=1
                     /gene="COL5A2"
                     /partial
     CDS             1240..1336
                     /product="pro-alpha 2(V) collagen"
                     /gene="COL5A2"
                     /codon_start=1
                     /translation="MMANWAEARPLLILIVLLGQFVSIKAQEEDED"
                     /partial
     enhancer        1391..1398
                     /gene="COL5A2"
BASE COUNT      525 a    282 c    397 g    467 t
ORIGIN
        1 agatcttggc aagtgtgagg gtggcacaaa agttcatcga taattttcct taaaatgcat
       61 gttcaactgg ggctatcata ttccctgcaa agctggctta aagctaataa taccaccatc
      121 tgcttttatg tagctctttg caatttggag cttcattaat aatacattac tcattttagt
      181 gtcactaaac cctgtacact ggtcagggta aagccctttc ttttctcaaa tgagaaaatt
      241 ggagtgcaca gagataaagg actatatgca catttacaaa attattgagt ggcagaacca
      301 ctcacaaaag gcagaagcaa gccttttttc atccaaaggt agagtacttc ccattcctct
      361 gcactgctta gtagactatt tttcaacatg gtaaaactct ctgggacaag aggaacctga
      421 agatgtggcc ccttaacaag agatgtggag aaattaggaa aggacatgct ttcttaattc
      481 aaattacaat gtatcacaaa ttcatttatc caaaatggtt ttctaacctg gactttacct
      541 gggcaacatt ctaataatct ccttccagag tatgggaaaa gaaaccgaat ctgagaaggg
      601 gataagaata ctccctattc agtcaaaaga aagggttaaa atgtgattgt ttaaagattt
      661 aaggtggaga agagagtctt gaattatcta aatgtaaaaa aactagggta aaaggctgga
      721 tttccttcgg aatgtctttt tcagcttata ggggaaaagt taaagggtgt gtgtctgggg
      781 ggaagggtta gggaggggaa aataaaaccc ttttcttcta acagcctttc ttaaaaaata
      841 aaagaaaaga gaaacaaatg tttgtttctg ttattaagcc ccatctatgc ttaaaagtta
      901 aatgaaatag ggaaagttca ggcacagaga cgcgtgttct gatttggttg tttaccatca
      961 atcagaccgt tgcttggcag acactggatg gttatgagcc tgaacaagct gaaaaggggc
     1021 aggaaaagaa gtggaggcag cattcttcct atttaaagct gcatcgcttg aaaaaagttt
     1081 tcgcagactg tgctggagct ggtgctgaaa aagggggttt gcagaggctg ccctggggct
     1141 ggtgctgaaa gaagagccca cagctgactt catggtgcta caataacctc agaatctact
     1201 tttcactctc aggagaaccc acatgtctaa tatttagaca tgatggcaaa ctgggcggaa
     1261 gcaagacctc tcctcattct tattgtttta ttagggcaat ttgtctcaat aaaagcccag
     1321 gaagaagacg aggatggtga gtttgccatt tgctttgctt gtagtgttta ttgcacggtt
     1381 tgggaaatag gtggaatgtt aagcctcagg aagagcgtga agaggaggtt ctggtttgaa
     1441 gtttgagaag ggggctgacg gatttgcacc tggaaaacga cttgaaagac aattgggatg
     1501 tttgtaaatc cggagcttct agatccaccg ttggagagag tacactacta aatttttctg
     1561 ggaaagccta caataagtcc ttttggctga gtgtgagagt gggacgttta aaataagaaa
     1621 agagtgaatg cttaaaacgg agcactaaag gcattttagt tagaggagct c
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