From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human, NAD(P)H:menadione oxidoreductase mRNA, complete cds.
Date: 5 Nov 92 23:11:50 GMT
Distribution: bionet
Checksum: 39718 5

LOCUS       HUMNMOR      2447 bp ss-mRNA            PRI       15-MAR-1989
DEFINITION  Human, NAD(P)H:menadione oxidoreductase mRNA, complete cds.
ACCESSION   J03934
KEYWORDS    NAD(P)H:menadione oxidoreductase; flavoprotein.
SOURCE      Human liver, cDNA to mRNA, clones HNMOR[1a,1b,1c,1d].
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2447)
  AUTHORS   Jaiswal,A.K., McBride,O.W., Adesnik,M. and Nebert,D.W.
  TITLE     Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase:
            cDNA sequence and localization of gene to chromosome 16
  JOURNAL   J. Biol. Chem. 263, 13572-13578 (1988)
  STANDARD  full automatic
COMMENT     Draft entry and computer-readable sequence for [1] kindly provided
            by A.Jaiswal, 16-JUN-1988.
               An Alu repeat is located between the polyadenylation signals
            located at positions 1460-1465 and 1838-1843.
FEATURES             Location/Qualifiers
     CDS             51..875
                     /gene="NMOR1"
                     /product="NAD(P)H:menadione oxidoreductase"
                     /codon_start=1
                     /translation="MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYA
                     MNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQF
                     PLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQG
                     IHGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDE
                     TPLYFAPSSLFDLNFQAGFLMKKEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK"
BASE COUNT      682 a    537 c    519 g    709 t
ORIGIN      131 bp upstream of PstI site; chromosome 16.
        1 cccggcaacc acgagcccag ccaatcagcg ccccggactg caccagagcc atggtcggca
       61 gaagagcact gatcgtactg gctcactcag agaggacctc cttcaactat gccatgaagg
      121 aggctgctgc agcggctttg aagaagaaag gatgggaggt ggtggagtcg gacctctatg
      181 ccatgaactt caatcccatc atttccagaa aggacatcac aggtaaactg aaggaccctg
      241 cgaactttca gtatcctgcc gagtctgttc tggcttataa agaaggccat ctgagcccag
      301 atattgtggc tgaacaaaag aagctggaag ccgcagacct tgtgatattc cagttccccc
      361 tgcagtggtt tggagtccct gccattctga aaggctggtt tgagcgagtg ttcataggag
      421 agtttgctta cacttacgct gccatgtatg acaaaggacc cttccggagt aagaaggcag
      481 tgctttccat caccactggt ggcagtggct ccatgtactc tctgcaaggg atccacgggg
      541 acatgaatgt cattctctgg ccaattcaga gtggcattct gcatttctgt ggcttccaag
      601 tcttagaacc tcaactgaca tatagcattg ggcacactcc agcagacgcc cgaattcaaa
      661 tcctggaagg atggaagaaa cgcctggaga atatttggga tgagacacca ctgtattttg
      721 ctccaagcag cctctttgac ctaaacttcc aggcaggatt cttaatgaaa aaagaggtac
      781 aggatgagga gaaaaacaag aaatttggcc tttctgtggg ccatcacttg ggcaagtcca
      841 tcccaactga caaccagatc aaagctagaa aatgagattc cttagcctgg atttccttct
      901 aacatgttat caaatctggg tatctttcca ggcttccctg acttgcttta gtttttaaga
      961 tttgtgtttt tctttttcca caaggaataa atgagaggga atcgaccgta ttcgtgcatt
     1021 tttggatgca tttttaactg attcttatga ttactatcat ggcatataac caaaatccga
     1081 ctgggctcaa gaggccactt agggaaagat gtagaaagat gctagaaaaa tgttctttaa
     1141 aggcatctac acaatttaat tcctcttttt agggtcaaag tttagggtac agttggctag
     1201 gtatcattca actctccaat gttctattaa tcacctctct gtagtttatg gtcagaaggg
     1261 aattgctcag agaaggtaaa agactgaatc tacctgccta agggacttaa cttgtttggt
     1321 agttagccat ctaatgcttg tttatgatat ttcttgcttt caattacaaa gcagttacta
     1381 atatgcctag cacaagtacc actcttggtc agcttttgtt gtttatatac agtacacaga
     1441 taccttgaaa ggaagagcta ataaatctct tctttgctgc agtcatctac ttttttttta
     1501 attaaaaaaa attttttttg aagcagtctt gctctgttac ccaggctgga gtgcagtggt
     1561 gtgatctcgg ctcactgcaa cctctgcctc ccaggttcca gcaattctcc tgcctcagcc
     1621 tccctagtag ctgggatgac aggcgcctgc catcatgcct gactaatttt tgtattttta
     1681 gtagagacgg cgtttcacca tgttggccag gctggtctca aactcctgac ctcaggtgat
     1741 ccgcctacct cagcctccca aagtgctggg attacaggcg tgatccacca cacctggccc
     1801 ttgcaatctt ctactttaag gtttgcagag ataaaccaat aaatccacac cgtacatctg
     1861 caatatgaat tccaagaaag gaaatagtac cttcaatact taaaaatagt cttccacaaa
     1921 aaatacttta tttctgatct atacaaattt tcagaaggtt attttcttta tcattgctaa
     1981 actgatgact taccatggga tggggtccag tcccatgacc ttggggtaca attgtaaacc
     2041 tagagtttta tcaactttgg tgaacagttt tggcataata gtcaatttct acttctggaa
     2101 gtcatctcat tccactgttg gtattatata attcaaggag aatatgataa aacactgccc
     2161 tcttgtggtg cattgaaaga agagatgaga aatgatgaaa aggttgcctg aaaaatggga
     2221 gacagcctct tacttgccaa gaaaatgaag ggattggacc gagctggaaa acctccttta
     2281 ccagatgctg actggcactg gtggtttttg ctctcgacat atccacaata gctgacggct
     2341 gggtgtttca gtttgcaaaa tattttgttg ccttcatctt cactgcaatt ttgtgtaaat
     2401 ttctcaaaga tctaattaaa taaataaaat tcatttctac agactca
//