From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Candida albicans pH responsive protein (PHR1) gene, complete cds.
Date: 9 Apr 92 10:05:38 GMT
Distribution: bionet
Checksum: 35914     5

LOCUS       YSAPHR1A     2034 bp ds-DNA             PLN       09-APR-1992
DEFINITION  Candida albicans pH responsive protein (PHR1) gene, complete cds.
ACCESSION   M90812
KEYWORDS    glycophospholipid-anchored membrane protein; pH responsive protein.
SOURCE      Candida albicans (strain SC5314) DNA.
  ORGANISM  Candida albicans
            Eukaryota; Fungi; Eumycota; Deuteromycotina.
REFERENCE   1  (bases 1 to 2034)
  AUTHORS   Saporito-Irwin,S.M. and Sypherd,P.S.
  TITLE     A pH-responsive gene,PHR1, from the dimorphic fungus Candida
            albicans encodes a glycophospholipid-anchored membrane protein
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     terminator      order(1959..1961,1974..1977,1995..1997)
                     /note="'pattern similarity to that proposed by Zarat &
                     Shermantag...tagt...ttt'"
                     /gene="PHR1"
     TATA_signal     28..34
                     /gene="PHR1"
     TATA_signal     103..109
                     /gene="PHR1"
     TATA_signal     128..134
                     /gene="PHR1"
     CDS             261..1916
                     /note="shows 56% identity to GPI-anchored gp115 from S.
                     cerevisiae"
                     /product="pH responsive protein"
                     /gene="PHR1"
                     /codon_start=1
                     /translation="MYSLIKSLATFATFATLFSLTLAKFESSTPPVEVVGNKFYFSNN
                     GSQFLIRGIAYQQDAAGSVSSGYDADPNRKYNDPLADRDACKRDVKYFKESNTNTLRV
                     YAIDPDKDHEECMKIFSDAGIYIVADLSEPTVSINRNNPEWNLDLYKRYTKVIDKMQE
                     YSNVLGFFAGNEVTNNRSNTDASAFVKAAIRDMKKYIKESDYRQIPVGYSSNDDEEIR
                     VAIADYFSCGSLDDRADFFGINMYEWCGKSTFETSGYKDRTEEIKNLTIPAFFSEYGC
                     NANRPRLFQEIGTLYSDKMTDVWSGGIVYMYFEEANKYGLVLVDGNSVKTLSDYNNYK
                     SEMNKISPSLAHTSTLSSSDASKTLQCPGTAASTWKAATNLPPTPDESYCDCISKSLE
                     CVVADDVDKEDYGDLFGQVCGYIDCSAISADGSKGEYGVASFCSDKDRLSYVLNQYYL
                     DQDKKSSACDFKGSASINSKASASGSCKAVSGVATGKASSSGGSSKSGSSSASASGSS
                     SSSTSSGSSSSSGVKATQQMSMVKLVSIITIVTAFVGGMSVVF"
BASE COUNT      618 a    378 c    386 g    652 t
ORIGIN
        1 aattcatcga cgcctcattc atactaatat aataggtgtt gcaacatcaa aatcatttca
       61 tcgctaatac aaacatccga gattaatctt gtccattggc aatataatta acaccactgc
      121 caatacatat aaatcaaatc agcattaact aatagtattt attaattact tagaaaagcc
      181 gggctgcgtt tttttgtttc attcatagat ttacttattt ccatttaaca taccaaacta
      241 caggttgaag ccaaaaaaaa atgtattcat taatcaaatc attggccaca tttgccacat
      301 ttgccacact cttttcatta actttagcca agtttgaatc gtccacccca ccagttgaag
      361 ttgttggtaa caaattttat ttttccaata atgggtctca gtttttaatc aggggtatcg
      421 cctatcagca agatgccgcg ggctcagttt cctccggtta cgacgccgat cctaatagaa
      481 aatacaatga tcctttagcc gatcgtgacg cttgtaaacg tgacgtcaag tatttcaaag
      541 aatcaaacac caatactttg agagtttatg ctattgaccc agataaggat catgaagagt
      601 gtatgaaaat tttcagtgac gctggtattt acattgttgc tgatttatca gaaccaactg
      661 tatcgattaa cagaaacaac ccagaatgga acttggattt atacaaacgt tatacaaaag
      721 tcattgataa gatgcaagaa tattctaatg ttttgggatt ttttgctggt aacgaagtaa
      781 ctaataatcg ttcaaatacc gatgcttctg catttgttaa ggctgccatt agagatatga
      841 agaaatacat caaggagtct gattatagac aaattcctgt tggttattca tccaatgatg
      901 acgaagaaat tagagtcgcc attgccgatt atttctcttg tggttcatta gatgatcgtg
      961 ctgatttctt tggtatcaat atgtatgaat ggtgtggcaa atcaactttc gaaacctcag
     1021 gttacaagga cagaactgaa gaaatcaaga acttgactat cccagccttc ttctccgaat
     1081 atggatgtaa tgctaaccgt ccacgtttgt tccaagaaat tggtaccttg tattccgata
     1141 agatgactga tgtttggtcc ggaggtattg tttatatgta ttttgaagag gctaacaaat
     1201 acggtttggt tctggttgat ggtaattcgg tcaagacatt atctgactac aacaattaca
     1261 aatcagaaat gaacaaaata agcccatccc ttgcccatac ttcaacatta tccagttctg
     1321 acgccagcaa gactttgcaa tgtccaggaa ctgctgctag cacttggaaa gctgcaacta
     1381 atttgccacc aactccagat gaaagttact gtgattgtat ttccaagtca ttagaatgtg
     1441 ttgttgctga cgatgttgat aaagaagact atggtgactt gtttggtcaa gtttgtggtt
     1501 atatcgattg ctcggctatt tctgccgatg gtagcaaagg tgaatatggt gttgcttcct
     1561 tctgttctga taaagatcgt ttgtcatatg tgttgaacca gtattacctt gaccaagaca
     1621 agaaatccag tgcttgtgat ttcaaaggca gtgcttcaat caatagcaag gctagtgcta
     1681 gtggcagctg caaagctgtt agtggagtag ctactggtaa ggcatcttcc tctggtggaa
     1741 gctccaaatc tggatcttcc tctgcatctg cttctggatc atcaagcagc agcaccagct
     1801 ctgggtccag ctcaagctct ggagttaaag caactcaaca aatgtctatg gtcaaattgg
     1861 tttcaattat tactattgtt actgcatttg ttggtggtat gtccgttgtt ttttaaatca
     1921 atgaagacta accgatatga agggttctgt tgtataggac gaatatatat agtttaataa
     1981 gagttcatta tttaaaagtt ccaatttgaa atcaacttgg tacacatatc tatt
//