From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for APO-1 cell surface antigen
Date: 24 Jul 92 10:06:28 GMT
Distribution: bionet
Checksum: 52247     6

LOCUS       HUMAPO1      2551 bp ss-mRNA            PRI       24-JUL-1992
DEFINITION  H.sapiens mRNA for APO-1 cell surface antigen
ACCESSION   X63717
KEYWORDS    APO-1 gene; cell surface antigen.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2551)
  AUTHORS   Oehm,A., Behrmann,I., Falk,W., Pawlita,M., Maier,G., Klas,C.,
            Li-Weber,M., Richards,S., Dhein,J., Trauth,B.C., Ponstingl,H. and
            Krammer,P.H.
  TITLE     Purification and molecular cloning of the APO-1 cell surface
            antigen, a member of the tumor necrosis factor/nerve growth factor
            receptor superfamily: Sequence identity with the F-as antigene
  JOURNAL   J. Biol. Chem. 267, 10709-10715 (1992)
  STANDARD  full automatic
COMMENT     *source: cell_line=SKW6.4; *source: clone_library=lambda gt10;
            *source: clone=14;
            From EMBL    entry HSAPO1;  dated 21-FEB-1992.
FEATURES             Location/Qualifiers
     CDS             221..1228
                     /product="APO-1 cell surface antigenprecursor"
                     /gene="APO-1"
                     /codon_start=1
                     /translation="MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTV
                     ETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCR
                     RCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCEHGIIKECTLT
                     SNTKCKEEGSRSNLGWLCLLLLPIPLIVWVKRKEVQKTCRKHRKENQGSHESPTLNPE
                     TVAINLSDVDLSKYITTIAGVMTLSQVKGFVRKNGVNEAKIDEIKNDNVQDTAEQKVQ
                     LLRNWHQLHGKKEAYDTLIKDLKKANLCTLAEKIQTIILKDITSDSENSNFRNEIQSL
                     V"
     sig_peptide     221..268
                     /gene="APO-1"
                     /codon_start=1
     mat_peptide     269..1225
                     /product="APO-1 cell surface antigen"
                     /gene="APO-1"
                     /codon_start=1
     polyA_signal    1857..1862
     polyA_signal    2378..2383
     polyA_signal    2544..2549
BASE COUNT      826 a    493 c    508 g    724 t
ORIGIN
        1 gcaagagtga cacacaggtg ttcaaagacg cttctgggga gtgagggaag cggtttacga
       61 gtgacttggc tggagcctca ggggcgggca ctggcacgga acacaccctg aggccagccc
      121 tggctgccca ggcggagctg cctcttctcc cgcgggttgg tggacccgct cagtacggag
      181 ttggggaagc tctttcactt cggaggattg ctcaacaacc atgctgggca tctggaccct
      241 cctacctctg gttcttacgt ctgttgctag attatcgtcc aaaagtgtta atgcccaagt
      301 gactgacatc aactccaagg gattggaatt gaggaagact gttactacag ttgagactca
      361 gaacttggaa ggcctgcatc atgatggcca attctgccat aagccctgtc ctccaggtga
      421 aaggaaagct agggactgca cagtcaatgg ggatgaacca gactgcgtgc cctgccaaga
      481 agggaaggag tacacagaca aagcccattt ttcttccaaa tgcagaagat gtagattgtg
      541 tgatgaagga catggcttag aagtggaaat aaactgcacc cggacccaga ataccaagtg
      601 cagatgtaaa ccaaactttt tttgtaactc tactgtatgt gaacactgtg acccttgcac
      661 caaatgtgaa catggaatca tcaaggaatg cacactcacc agcaacacca agtgcaaaga
      721 ggaaggatcc agatctaact tggggtggct ttgtcttctt cttttgccaa ttccactaat
      781 tgtttgggtg aagagaaagg aagtacagaa aacatgcaga aagcacagaa aggaaaacca
      841 aggttctcat gaatctccaa ccttaaatcc tgaaacagtg gcaataaatt tatctgatgt
      901 tgacttgagt aaatatatca ccactattgc tggagtcatg acactaagtc aagttaaagg
      961 ctttgttcga aagaatggtg tcaatgaagc caaaatagat gagatcaaga atgacaatgt
     1021 ccaagacaca gcagaacaga aagttcaact gcttcgtaat tggcatcaac ttcatggaaa
     1081 gaaagaagcg tatgacacat tgattaaaga tctcaaaaaa gccaatcttt gtactcttgc
     1141 agagaaaatt cagactatca tcctcaagga cattactagt gactcagaaa attcaaactt
     1201 cagaaatgaa atccaaagct tggtctagag tgaaaaacaa caaattcagt tctgagtata
     1261 tgcaattagt gtttgaaaag attcttaata gctggctgta aatactgctt ggttttttac
     1321 tgggtacatt ttatcattta ttagcgctga agagccaaca tatttgtaga tttttaatat
     1381 ctcatgattc tgcctccaag gatgtttaaa atctagttgg gaaaacaaac ttcatcaaga
     1441 gtaaatgcag tggcatgcta agtacccaaa taggagtgta tgcagaggat gaaagattaa
     1501 gattatgctc tggcatctaa catatgattc tgtagtatga atgtaatcag tgtatgttag
     1561 tacaaatgtc tatccacagg ctaaccccac tctatgaatc aatagaagaa gctatgacct
     1621 tttgctgaaa tatcagttac tgaacaggca ggccactttg cctctaaatt acctctgata
     1681 attctagaga ttttaccata tttctaaact ttgtttataa ctctgagaag atcatattta
     1741 tgtaaagtat atgtatttga gtgcagaatt taaataaggc tctacctcaa agacctttgc
     1801 acagtttatt ggtgtcatat tatacaatat ttcaattgtg aattcacata gaaaacatta
     1861 aattataatg tttgactatt atatatgtgt atgcatttta ctggctcaaa actacctact
     1921 tctttctcag gcatcaaaag cattttgagc aggagagtat tactagagct ttgccacctc
     1981 tccatttttg ccttggtgct catcttaatg gcctaatgca cccccaaaca tggaaatatc
     2041 accaaaaaat acttaatagt ccaccaaaag gcaagactgc ccttagaaat tctagcctgg
     2101 tttggagata ctaactgctc tcagagaaag tagctttgtg acatgtcatg aacccatgtt
     2161 tgcaatcaaa gatgataaaa tagattctta tttttccccc acccccgaaa atgttcaata
     2221 atgtcccatg taaaacctgc tacaaatggc agcttataca tagcaatggt aaaatcatca
     2281 tctggattta ggaattgctc ttgtcatacc cccaagtttc taagatttaa gattctcctt
     2341 actactatcc tacgtttaaa tatctttgaa agtttgtatt aaatgtgaat tttaagaaat
     2401 aatatttata tttctgtaaa tgtaaactgt gaagatagtt ataaactgaa gcagatacct
     2461 ggaaccacct aaagaacttc catttatgga ggattttttt gccccttgtg tttggaatta
     2521 taaaatatag gtaaaagtac gtaattaaat a
//