From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Sheep immunoglobulin epsilon heavy chain (IgE) variable region,
Date: 26 Aug 92 10:00:53 GMT
Distribution: bionet
Checksum: 02284     5

LOCUS       SHPIGEVDJC   1785 bp ss-mRNA            MAM       26-AUG-1992
DEFINITION  Sheep immunoglobulin epsilon heavy chain (IgE) variable region,
            diversity region, joining region, and constant regions 1-4 mRNA.
ACCESSION   M84356
KEYWORDS    constant region; diversity region; epsilon heavy chain;
            immunoglobulin heavy chain; joining region; variable region.
SOURCE      Ovis aries lymph node cDNA to mRNA.
  ORGANISM  Ovis aries
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE   1  (bases 1 to 1785)
  AUTHORS   Engwerda,C.R., Sandeman,R.A., Stuart,S.J. and Sandeman,M.
  TITLE     The isolation and characterization of sheep immunoglobulin E heavy
            chain cDNA
  JOURNAL   Vet. Immunol. Immunopathol. (1992) In press
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     sig_peptide     1..57
                     /gene="IgE"
                     /codon_start=1
     mat_peptide     1..1689
                     /gene="IgE"
                     /codon_start=1
     CDS             1..1692
                     /product="immunoglobulin epsilon-chain"
                     /gene="IgE"
                     /codon_start=1
                     /translation="DEPTVDPPLCALSPQRVLSQVRLQESGPSLVKPSQTLSLTCTVS
                     GFSLDDDPVGWVRQAPGKVPEWLGLIGYDGDTYYNPALKSRLSITRDTSKSQVSLSLI
                     SVTTEDTAVYYCTGEPTYSKYASYWSPGLLVTVSSVSSQHPSIYPLRTCCIKETSVAL
                     GCLVKDYFPGSVAVTWDTAPLDGSTLTFPSIQMANSSLYVTTSQLTVSGEQPKQFTCS
                     VFHAETNTTAMKTVSTECAKNFSDPSVRLFYSSCDPSGDTHTTIQLLCRISGYTPGKI
                     KVTWLVDGHESKELYAQPGPEIQEGNLTTTYSEVNITQGQWASEKTYTCRVNYYGFNF
                     DNHARRCTAESEPRGVSTYLIPPTPLELYVNKSPKITCLVVDLASTNNLSLTWSRANG
                     KPVHADPLDIKHQFNGTITVTSTLPVNVIDWVEGETYYCKVSHGDLPKDIQRSISKDV
                     GKRVAPKVYVFWPDRKELENQEELTLTCLIQKFFPKDISVRWLRNKELMREGQHTTTQ
                     PDRADNNSLAFFAYSRLAVPKASWKMDDEFTCQVIHEALPKTRTLEKSVFINSGK"
                     /partial
     3'UTR           1693..1785
     polyA_signal    1761..1766
                     /gene="IgE"
     polyA_site      1785
                     /gene="IgE"
BASE COUNT      413 a    596 c    458 g    318 t
ORIGIN
        1 gatgaaccca ctgtggaccc tcctctttgt gctctcagcc cccagagggt cctgtcccag
       61 gtgcggctgc aggagtcggg acccagcctg gtgaagccct cacagaccct ctccctcacc
      121 tgcacggtct ctggattctc attagacgac gatcctgtag gctgggtccg ccaggctcca
      181 ggaaaggtgc cggagtggct tggtcttata ggctatgatg gagatacata ctataatccg
      241 gccctgaaat cccgactcag cataaccagg gacacctcca agagccaagt ctccctgtca
      301 ctgatcagcg tcacaactga ggacacggcc gtgtactact gtacaggaga acccacttat
      361 agcaaatatg ccagttattg gagcccagga ttgctggtca ccgtctcctc agtctccagc
      421 cagcatccat ccatctaccc cttgaggacc tgttgcataa aagaaacctc tgtggccctg
      481 ggctgcctgg tcaaggacta cttcccaggg tcagtggctg tgacctggga cacagcgccc
      541 ctggacggga gcaccctgac cttccctagc atccaaatgg cgaactccag tctctacgtc
      601 accaccagcc agctgaccgt ctcgggcgag cagcccaagc agttcacctg cagtgttttc
      661 cacgctgaga ctaacaccac tgccatgaag accgtcagca ctgagtgcgc caagaacttc
      721 agcgacccct cggtgaggct cttctactcc tcctgtgacc ccagcggcga cacccacacc
      781 accatccagc tcctgtgccg gatctccggc tacaccccag gcaagatcaa ggtcacctgg
      841 ctggtggacg ggcacgagtc caaagaactg tatgcacagc ccggccccga gatacaggag
      901 ggcaatctga ccaccaccta cagcgaagtc aacatcacac agggccagtg ggcgtccgag
      961 aaaacctaca cctgccgggt caactattac ggcttcaact tcgacaacca cgcccgcagg
     1021 tgcacagccg agtccgagcc ccgcggcgtg agcacctacc tgatcccacc cacccccctc
     1081 gagctgtacg tcaacaagtc gcccaagatc acctgcctgg ttgtggacct ggccagcacg
     1141 aataacttga gcctgacctg gtcgagggca aacgggaaac ctgtgcacgc agaccccctc
     1201 gacatcaagc atcagttcaa cgggacgatc accgtcacgt ccaccctgcc ggtgaacgtc
     1261 attgactggg ttgaaggcga gacctactac tgcaaagtga gccacggcga cctgcccaag
     1321 gatatccaga gatccatctc caaggatgtt ggcaagcgtg tggcccccaa ggtctacgtg
     1381 ttctggccag acagaaagga gctggagaat caggaggagc tcaccctcac ctgcctgatc
     1441 cagaaattct tccccaagga catctctgtg cggtggctgc gtaacaagga actgatgcgg
     1501 gaaggccagc acaccaccac gcagcccgac agggccgaca acaacagcct cgccttcttc
     1561 gcctacagcc gcctggcggt ccccaaggcc agctggaaga tggacgatga gttcacctgc
     1621 caagtgatcc acgaggcact gcccaagact aggaccctgg agaaatcggt gttcattaac
     1681 agcggtaaat aatgcccgcc ctcccacgcg cccctctccc ggggcagggg aggggccagt
     1741 gggactttct gtccaccgtc aataaacact ctggtgcctg ctcag
//