From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat mRNA for hepatocyte nuclear factor 4 (HNF4).
Date: 24 Jul 92 10:09:34 GMT
Distribution: bionet
Checksum: 18944     5

LOCUS       RATHNF4CL    1446 bp ss-mRNA            ROD       24-JUL-1992
DEFINITION  Rat mRNA for hepatocyte nuclear factor 4 (HNF4).
ACCESSION   D10554
KEYWORDS    hepatocyte nuclear factor 4;
            steroid/thyroid hormone receptor superfamily; transcription factor.
SOURCE      Rat (strain Wistar) liver, cDNA to mRNA, clone HNF-4CL4.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (sites)
  AUTHORS   Sladek,F.M., Zhong,W., Lai,E. and Darnell,J.E.
  TITLE     Liver-enriched transcription factor HNF-4 is a novel member of the
            steroid hormone receptor superfamily
  JOURNAL   Genes Dev. 4, 2353-2365 (1990)
  STANDARD  full staff_review
REFERENCE   2  (bases 1 to 1446)
  AUTHORS   Hata,S., Tsukamoto,T. and Osumi,T.
  TITLE     A novel isoform of rat hepatocyte nuclear factor 4 (HNF-4)
  JOURNAL   Biochim. Biophys. Acta 1131, 211-213 (1992)
  STANDARD  full staff_review
COMMENT     Submitted (21-FEB-1992) to DDBJ by:
            Shingo Hata
            Faculty of Science
            Himeji Institute of Technology
            Kamigori, Ako-gun
            Hyogo 678-12
            Japan
            Phone:  07915-8-0194
            Fax:    07915-8-0193
            [1]  sites.
FEATURES             Location/Qualifiers
     CDS             44..1441
                     /product="hepatocyte nuclear factor 4"
                     /codon_start=1
                     /translation="MDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNSSNS
                     LGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQ
                     CRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSQQITSPI
                     SGINGDIRAKKIANITDVCESMKEQLLVLVEWAKYIPAFCELLLDDQVALLRAHAGEH
                     LLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNE
                     YACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPT
                     LQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSASDAPHAHHPLHPHLMQEHMGTN
                     VIVANTMPSHLSNGQMCEWPRPRGQAATPETPQPSPPSGSGSESYKLLPGAITTIVKP
                     PSAIPQPTITKQEAI"
     misc_feature    1269..1298
                     /note="novel exta segment"
BASE COUNT      342 a    427 c    391 g    286 t
ORIGIN
        1 ggatccgtag aggagaatgc gactctctaa aaccctcgcc gacatggaca tggctgacta
       61 cagtgctgcc ttggacccag cctacaccac cctggagttt gaaaatgtgc aggtgttgac
      121 catgggcaat gacacatccc catctgaagg tgccaacctc aactcatcca acagcctggg
      181 tgtcagtgcc ctgtgtgcca tctgtggcga tcgggccact ggcaaacact acggagcctc
      241 aagctgtgac ggctgcaagg gattcttcag gaggagcgtg aggaagaacc acatgtactc
      301 ctgcaggttt agcaggcagt gcgtggtaga caaagataag aggaaccagt gtcgttactg
      361 caggctcaag aagtgcttcc gggctggcat gaagaaagaa gccgtccaaa atgagcggga
      421 tcggatcagc acgcggaggt caagctacga ggacagcagc ctaccctcca ttaatgcgct
      481 cctgcaggca gaggtcctgt ctcagcagat cacctccccc atctctggga tcaatggcga
      541 cattcgggcc aagaagattg ccaacatcac ggatgtgtgt gagtctatga aggagcagct
      601 gctggttctg gtcgaatggg ccaagtacat cccggccttc tgtgaacttc ttctggatga
      661 ccaggtggcg ctgctcagag cccacgctgg tgagcacctg ctgcttggag ccaccaagag
      721 gtccatggtg ttcaaggatg tgctgctcct aggcaatgac tacatcgtcc ctcggcactg
      781 tccagagcta gcagagatga gccgtgtgtc cattcgcatc ctcgatgagc tggtcttgcc
      841 cttccaagag ctgcagatcg atgataatga atacgcctgc ctcaaagcca tcatcttctt
      901 tgacccagat gccaaggggc tgagtgaccc aggcaagatc aagcggctgc ggtcacaggt
      961 gcaggtgagc ctggaggatt acatcaacga ccggcagtat gactctcggg gtcgttttgg
     1021 agagctgctg ctgctcctgc ccactctgca gagcattacc tggcagatga tcgagcagat
     1081 ccagttcatc aagctctttg gcatggccaa gattgacaac ctgctgcagg agatgctgct
     1141 tggagggtct gccagtgacg cgccccacgc ccaccacccc ctgcaccctc acctgatgca
     1201 agaacacatg ggcaccaatg tcatagttgc caacacgatg ccctctcacc tcagcaatgg
     1261 acagatgtgt gagtggcccc ggcccagggg gcaggcagcc acccctgaga ctccacagcc
     1321 atcaccacca agtggctctg gatctgaatc ctacaagctc ctgccaggag ccatcaccac
     1381 catcgtcaag cctccctctg ccatccccca gccaacgatc accaagcagg aagccatcta
     1441 gaattc
//