From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mucin 2 (MUC2) mRNA sequence.
Date: 21 Dec 92 20:46:38 GMT
Distribution: bionet
Checksum: 16557 7

LOCUS       HUMIMUCB     3108 bp ss-mRNA            PRI       20-NOV-1992
DEFINITION  Human mucin 2 (MUC2) mRNA sequence.
ACCESSION   M94132
KEYWORDS    mucin.
SOURCE      Homo sapiens intestine cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3108)
  AUTHORS   Gum,J.R.Jr., Hicks,J.W., Toribara,N.W., Rothe,E.M., Lagace,R.E. and
            Kim,Y.S.
  TITLE     The human MUC2 intestinal mucin has cysteine- rich subdomains
            located both upstream and downstream of its central repetitive
            region
  JOURNAL   J. Biol. Chem. 267, 21375-21383 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     polyA_signal    3088..3093
     polyA_site      3108
     CDS             <1..2955
                     /note="ORF"
                     /codon_start=1
                     /translation="GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLS
                     TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPS
                     TVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYG
                     DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP
                     DFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGC
                     CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDP
                     NDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINY
                     VVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCE
                     AAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQ
                     CHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVE
                     CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVG
                     PDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD
                     TCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQP
                     GSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQT
                     HCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIP
                     GSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYS
                     AKAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSR
                     RARRSPRHLGSG"
BASE COUNT      646 a   1112 c    791 g    559 t
ORIGIN      
        1 gggcccccca cccacacaag cacagcaccg attgctgagt tgaccacatc caatcctccg
       61 cctgagtcct caacccctca gacctctcgg tccacctctt cccctctcac ggagtcaacc
      121 acccttctga gtaccctacc acctgccatt gagatgacca gcacggcccc accctccaca
      181 cccacggcac ccacgaccac gagcggaggc cacacactgt ctccaccgcc cagcaccacc
      241 acgtcccctc caggcacccc cactcgcggt accacgaccg ggtcatcttc agcccccacc
      301 cccagcactg tgcagacgac caccaccagt gcctggaccc caacgccgac cccactctcc
      361 acacccagca tcatcaggac cacaggcctg aggccctacc cttcctctgt gcttatctgc
      421 tgtgtcctga acgacaccta ctacgcacca ggtgaggagg tgtacaacgg cacatacgga
      481 gacacctgtt atttcgtcaa ctgctcactg agctgtacgt tggagttcta taactggtcc
      541 tgcccatcca cgccctcccc aacacccacg ccctccaagt cgacgcccac gccttccaag
      601 ccatcgtcca cgccctccaa gccgacgccc ggcaccaagc cccccgagtg cccagacttt
      661 gatcctccca gacaggagaa cgagacttgg tggctgtgcg actgcttcat ggccacgtgc
      721 aagtacaaca acacggtgga gatcgtgaag gtggagtgtg agccgccgcc catgcccacc
      781 tgctccaacg gcctccaacc cgtgcgcgtc gaggaccccg acggctgctg ctggcactgg
      841 gagtgcgact gctactgcac gggctggggc gacccgcact atgtcacctt cgacggactc
      901 tactacagct accagggcaa ctgcacctac gtgctggtgg aggagatcag cccctccgtg
      961 gacaacttcg gagtttacat cgacaactac cactgcgatc ccaacgacaa ggtgtcctgt
     1021 ccccgcaccc tcatcgtgcg ccacgagacc caggaggtgc tgatcaagac cgtgcatatg
     1081 atgcccatgc aggtgcaggt gcaggtgaac aggcaggcgg tggcactgcc ctacaagaag
     1141 tacgggctgg aggtgtacca gtctggcatc aactacgtgg tggacatccc cgagctgggt
     1201 gtcctcgtct cctacaatgg cctgtccttc tccgtcaggc tgccctacca ccggtttggc
     1261 aacaacacca agggccagtg tggcacctgc accaacacca cctccgacga ctgcattctg
     1321 cccagcgggg agatcgtctc caactgtgag gctgcggctg accagtggct ggtgaacgac
     1381 ccctccaagc cacactgccc ccacagcagc tccacgacca agcgcccggc cgtcactgtg
     1441 cccgggggcg gtaaaacgac cccacacaag gactgcaccc catctcccct ctgccagctc
     1501 atcaaggaca gcctgtttgc ccagtgccac gcactggtgc ccccgcagca ctactacgat
     1561 gcctgcgtgt tcgacagctg cttcatgccg ggctcgagcc tggagtgcgc cagtctgcag
     1621 gcctacgcag ccctctgtgc ccagcagaac atctgcctcg actggcggaa ccacacgcat
     1681 ggggcctgct tggtggagtg cccatctcac agggagtacc aggcctgtgg ccctgcagaa
     1741 gagcccacgt gcaaatccag ctcctcccag cagaacaaca cagtcctggt ggaaggctgc
     1801 ttctgtcctg agggcaccat gaactacgct cctggctttg atgtctgcgt gaagacctgc
     1861 ggctgtgtgg gacctgacaa tgtgcccaga gagtttgggg agcacttcga gttcgactgc
     1921 aagaactgtg tctgcctgga gggtggaagt ggcatcatct gccaacccaa gaggtgcagc
     1981 cagaagcccg ttacccactg cgtggaagac ggcacctacc tcgccacgga ggtcaaccct
     2041 gccgacacct gctgcaacat taccgtctgc aagtgcaaca ccagcctgtg caaagagaag
     2101 ccctccgtgt gcccgctggg attcgaagtg aagagcaaga tggtgcctgg aaggtgctgt
     2161 cccttctact ggtgtgagtc caagggggtg tgtgttcacg ggaatgctga gtaccagccc
     2221 ggttctccag tttattcctc caagtgccag gactgcgtgt gcacggacaa ggtggacaac
     2281 aacaccctgc tcaacgtcat cgcctgcacc cacgtgccct gcaacacctc ctgcagccct
     2341 ggcttcgaac tcatggaggc ccccggggag tgctgtaaga agtgtgaaca gacgcactgt
     2401 atcatcaaac ggcccgacaa ccagcacgtc atcctgaagc ccggggactt caagagcgac
     2461 ccgaagaaca actgcacatt cttcagctgc gtgaagatcc acaaccagct catctcgtcc
     2521 gtctccaaca tcacctgccc caactttgat gccagcattt gcatcccggg ctccatcaca
     2581 ttcatgccca atggatgctg caagacctgc acccctcgca atgagaccag ggtgccctgc
     2641 tccaccgtcc ccgtcaccac ggaggtttcg tacgccggct gcaccaagac cgtcctcatg
     2701 aatcattgct ccgggtcctg cgggacattt gtcatgtact cggccaaggc ccaggccctg
     2761 gaccacagct gctcctgctg caaagaggag aaaaccagcc agcgtgaggt ggtcctgagc
     2821 tgccccaatg gcggctcgct gacacacacc tacacccaca tcgagagctg ccagtgccag
     2881 gacaccgtct gcgggctccc caccggcacc tcccgccggg cccggcgctc ccctaggcat
     2941 ctggggagcg ggtgagcggg gtgggcacag cccccttcac tgccctcgac agctttacct
     3001 cccccggacc ctctgagcct cctaagctcg gcttcctctc ttcagatatt tattgtctga
     3061 gtctttgttc agtccttgct ttccaataat aaactcaggg ggacatgc
//