HDTenEightyP/NetNews huggingface dataset:
From: bwc@bcm.tmc.edu (Robert Cottingham)
Newsgroups: bionet.molbio.gene-linkage
Subject: Error analysis
Date: 19 Nov 1992 03:12:30 GMT
Organization: Baylor College of Medicine, Houston, Tx
Distribution: world
Reply-To: bwc@bcm.tmc.edu
NNTP-Posting-Host: raven.imgen.bcm.tmc.edu
Originator: bwc@raven.imgen.bcm.tmc.edu


If anyone has suggestions about software which detects possible errors in human linkage data, I would appreciate hearing about it.  I am not
refering to directly detectable errors such as incompatible inheritance,
but rather possible errors such as double recombination over a very
short interval, or many recombinants within a family.

The data I am interested in analyzing contains about 200 individuals
within a single pedigree.

Thanks for any suggestions.

-Bob

        ------------------------------------------------------------
        Bob Cottingham                  Phone:  713/798-4275
        Cell Biology                    Fax:        798-5386
        Baylor College of Medicine      Email: bwc@bcm.tmc.edu
        Houston, TX   77030
        ------------------------------------------------------------
From: HAINES@HELIX.MGH.HARVARD.EDU ("Jonathan L. Haines")
Newsgroups: bionet.molbio.gene-linkage
Subject: error analysis
Date: 19 Nov 92 17:23:16 GMT
Distribution: bionet


Off the top of my head, I know of two programs that can detect errors of
phase.  The first is the CHROMPIC option of CRI-MAP which uses maximum
likelihood methods to identify probable phase and will output those
chromosomes with double recombinants.  It is usually used with reference
(CEPH) data, but can handle general pedigrees, if the disease phenotype
can be assumed as a simple single gene.  I don't know how well it will work
if there are many missing (untyped) individuals in the pedigree.
     The second program is CHROMLOOK, but it probably is not appropriate,
since it requires the families to be broken down into individual sibships,
and expects both parents to be typed (e.g. like CEPH pedigrees).  However,
I personally think it has better output (then again, I would since I
wrote it!).  It uses non-likelihood methods to assume phase.

Jonathan Haines
From: HAINES@HELIX.MGH.HARVARD.EDU ("Jonathan L. Haines")
Newsgroups: bionet.molbio.gene-linkage
Subject: error analysis
Date: 19 Nov 92 17:30:44 GMT
Distribution: bionet

MAPMAKER 3.0's error analysis is publiished in the November issue of
Genomics, page 604.

Jonathan Haines
From: lshi@sciborg.uwaterloo.ca (Lily L.Shi)
Newsgroups: bionet.molbio.gene-linkage
Subject: test
Date: 17 Nov 92 16:35:44 GMT
Organization: University of Waterloo
Originator: lshi@sciborg.uwaterloo.ca
X-Mailer: ELM [version 2.3 PL11]

this  is a test.
From: ibacon@uniwa.uwa.edu.au (Ian Bacon)
Newsgroups: bionet.molbio.ageing
Subject: Age research in Australia
Date: 20 Nov 1992 17:19:32 +0800
Organization: The University of Western Australia
NNTP-Posting-Host: uniwa.uwa.edu.au
X-Newsreader: Tin 1.1 PL5

After having read about age research being carried out in the US and
elsewhere I have grown curious about age research in Australia. Is
anyone doing this research, how is it being treated by the academic
establishment?

All comments welcome.

Ian Bacon
Newsgroups: bionet.molbio.ageing
From: erikl@ibg.uit.no (Erik Lovaas)
Subject: Re: Alzheimer's disease
Keywords: Alzheimers, cognition, neuropathology
Organization: UIT
Date: Sat, 21 Nov 1992 05:59:38 GMT
Summary: Relating the neuropathology to cognitive deficits

In article <1eh9kkINN8vo@pollux.usc.edu> jdevlin@pollux.usc.edu (Joseph T. Devlin) writes:
>Subject: Alzheimer's disease
>From: jdevlin@pollux.usc.edu (Joseph T. Devlin)
>Date: 19 Nov 92 23:57:08 GMT
>Keywords: Alzheimers, cognition, neuropathology
>Summary: Relating the neuropathology to cognitive deficits

>Hello all,
>  I have been doing some research into the Alzheimer's
>literature and I characteristicly find a dichotomy between
>the cognitive deficits of AD and the known neuropathology
>of the disease.  As yet I haven't seen even any suggestions
>as to how the two might relate.

Dear Joe:

At present there are speculations if Alzheimeres disease somehow relate
to oxidative destructions of brain tissue, and if antioxidants may prevent
such effects. Some recent litterature is listed:

1. Richardson, J. S., K. V. Subbarao, and L. C. Ang. 1992. On the
possible role of iron-induced free radical peroxidation in neural
degeneration in Alzheimer's disease. Ann.NY Acad.Sci. 648:326-327. 
 
2. Backon, J. 1991. Dementia in cancer patients undergoing
chemotherapy:  Implication of free radical injury and relevance to
Alzheimer disease. Med.Hypotheses 35:146-147. 
 
3. Evans, P. H., J. Klinowski, and E. Yano. 1991. Cephaloconiosis:  A
free radical perspective on the proposed particulate-induced
etiopathogenesis of Alzheimer's dementia and related disorders.
Med.Hypotheses 34:209-219. 
Notes     : By analogy to the etiology of the pneumoconioses, exogenous
dust-induced diseases of the lung, and endogenous crystal- induced
arthropathies such as gout, it is proposed that Alzheimer's dementia and
allied disorders are causally related to the accumulation of fibriform
inorganic deposits within the brain. Hence the neonosological term
'Cephaloconiosis'. It is proposed that: 1) either by the extrinsic migration
or intrinsic formation and deposition of insoluble and persistent inorganic
reactive nidi, the particle- induced generation of tissue-damaging
free-radical oxygen metabolites by stimulated brain glial macrophage-type
and allied phagocytic cells,  provides a rationale for the etiopathogenesis
of neurodegenerative processes; 2) the modulation of the injurious
oxidative metabolic reaction by micronutrient and pharmacological
antioxidant agents is a rational and potentially feasible strategy for
future therapeutic clinical investigations. AUTHOR  
 
4. Perrin, R., S. Brianon, C. Jeandel, Y. Artur, A. Minn, F. Penin, and G.
Siest. 1990. Blood activity of Cu/Zn superoxide dismutase, glutathione
peroxidase and catalase in Alzheimer's disease:  A case-control study.
Gerontology 36:306-313. 
 
5. Subbarao, K. V., J. S. Richardson, and L. C. Ang. 1990. Autopsy
samples of Alzheimer's cortex show increased peroxidation in vitro.
J.Neurochem. 55:342-345. 
 
6. Volicer, L. and P. B. Crino. 1990. Involvement of free radicals in
dementia of the Alzheimer type:  A hypothesis. Neurobiol.Aging
11:567-571. 
 
Erik Lovaas
From: jdevlin@pollux.usc.edu (Joseph T. Devlin)
Newsgroups: bionet.molbio.ageing
Subject: Alzheimer's disease
Date: 19 Nov 1992 15:57:08 -0800
Organization: University of Southern California, Los Angeles, CA
Distribution: world
NNTP-Posting-Host: pollux.usc.edu
Summary: Relating the neuropathology to cognitive deficits
Keywords: Alzheimers, cognition, neuropathology

Hello all,
  I have been doing some research into the Alzheimer's
literature and I characteristicly find a dichotomy between
the cognitive deficits of AD and the known neuropathology
of the disease.  As yet I haven't seen even any suggestions
as to how the two might relate.
  What I am interested in is what the possible implications
of amyloid plaque build-up and neurofibrillary tangles might
be.  I understand that in general noone knows but there must
be some suggestions out there.  If anyone could point me to
appropriate literature I would appreciate it.  In addition,
if anyone was willing to make off-the-record speculations
within this group I would appreciate reading those too.
  Thank you for your help.

						- Joe

*************************************************************************
Joseph Devlin                      * email: jdevlin@pollux.usc.edu
University of Southern California  *
Department of Computer science     * "The axon doesn't think.
Los Angeles, CA 90089              *  It just ax."  George Bishop
*************************************************************************
From: B2G@CU.NIH.GOV
Newsgroups: bionet.molbio.genome-program
Subject: Pre and Post-Doctoral Training Supported by NCHGR
Date: 23 Nov 92 15:37:53 GMT
Reply-To: B2G@NIHCU
Distribution: bionet

The National Center for Human Genome Research (NCHGR), NIH,
would like to remind the scientific community that funds are
available to support research training at three career levels:
pre-doctoral training through institutional training grants;
individual post-doctoral fellowships for advance training in
genomic analysis and senior fellowships for established scientists
who wish to acquire new skills in genomic research.  We are
also encouraging training in areas of interest to the NCHGR's
Ethical, Legal and Social Implications (ELSI) Program.

All training will be supported under the National Research
Service Award mechanism.  Therefore, participation in this
program is limited to U.S. scientists and permanent residents
of the United States only.

The next application receipt date for individual fellowship
applications and institutional training grant applications is
January 10, 1993.

For additional information about training opportunities,
please contact the following individuals:  ELSI Program--
Dr. Eric Juengst at (301) 402-0911; e-mail address is
EJS@NIHCU or EJS@CU.NIH.GOV.; Genomic Analysis and Tech-
nology Development--Dr. Elise Feingold (individual post-
doctoral fellowships) at (301) 496-7531; e-mail address is
FEY@NIHCU or FEY@CU.NIH.GOV. or Dr. Bettie J. Graham
(institutional training grants) at (301) 496-7531; e-mail
From: spike@FLOREY.BIOSCI.UQ.OZ.AU (Stephen Pike)
Newsgroups: bionet.molbio.genome-program
Subject: (none)
Date: 19 Nov 92 01:59:58 GMT
Distribution: bionet

help
From: B2G@CU.NIH.GOV
Newsgroups: bionet.molbio.genome-program
Subject: Pre- and Post-Doctoral Training Supported by the National
Date: 23 Nov 92 13:44:40 GMT
Reply-To: B2G@NIHCU
Distribution: bionet

The National Center for Human Genome Research, NIH would like
to remind the scientific community that funds are available
to support research training at three career levels:  pre-
doctoral fellowships through institutional training grants,
individual post-doctoral fellowships for advance training
in genomic analysis and senior fellowships for established
scientists who wish to acquire new skills relevant to
genomic research.  We are also encouraging training in
areas of interest to the NCHGR's Ethical, Legal and Social
Implications (ELSI) Program.

All training will be supported under the National Research
Service Award mechanism.  Therefore, participation in this
program is limited to U.S. scientists or permanent residents
of the United States.

The next application receipt date for individual fellowship
applications and institutional training grant applications is
January 10, 1993.  For additional information about training
opportunities, please contact the following individuals:

ELSI Program--Dr. Eric Juengst at (301) 402-0911; e-mail
address EJS@NIHCU or EJS@CU.NIH.GOV.

Genomic Analysis and Technology Development: (1) Dr. Elise
Feingold (individual post-doctoral fellowships) at
(301) 496-7531; e-mail address--FEY@NIHCU or FEY@CU.NIH.GOV.
or (2) Dr. Bettie J. Graham (institutional training grants)
at (301) 496-7531; e-mail address--B2g@NIHCU or B2G@CU.NIH.GOV.
From: smith-una@yale.edu (Una Smith)
Newsgroups: bionet.jobs
Subject: Ecology/Forestry position announcement
Date: 20 Nov 1992 10:34:33 -0500
Organization: Yale University Science & Engineering UNIX(tm), New Haven, CT 06520-2158
Distribution: world
NNTP-Posting-Host: minerva.cis.yale.edu

POSITION ANNOUNCEMENT:  SENIOR RESEARCH TECHNICIAN
The University of Tennessee
National Park Service-Cooperative Park Studies Unit

Type:  Regular Full-time with Benefits
Start Date: As soon as suitable applicant is found.
Duration:  This is a soft-money position with continuation
contingent upon funding being renewed each year.  However, the
funding agency (National Park Service) has established the work
as part of a long-term, base-funded, project which should
continue for many years.

Location:  The incumbent is an employee of the Department of
Forestry, Wildlife and Fisheries, Institute of Agriculture, The
University of Tennessee and is stationed at the UT Agricultural
Campus in Knoxville.  The assignment will include field sampling
at the Great Smoky Mountains National Park, a 1/2 million acre
park on the border of Tennessee and North Carolina.

Salary: Minimum of $14,310 / year with medical, vacation, and
retirement benefits.

Requirements:
Applicants must have a Bachelor's degree or the equivalent of an
Associate's degree with at least two years of experience in a
natural resource related field.  The candidate must have field
sampling experience on the chemistry or biology of aquatic
systems.

Assignment:
The successful applicant's responsibilities will include the
collection of water (precipitation, throughfall, soil solution)
and benthic invertebrate samples as part of a stream and
watershed monitoring program in the Great Smoky Mountains
National Park.

The work will include: collecting samples at the Park,
transporting samples to our laboratory at UT, and conducting
certain laboratory analyses (e.g. pH and conductance).  The
individual will also assist in the laboratory in the preparation
of samples for detailed chemical analyses.
==========================================================
To Apply:
Submit a letter of application, C.V., and supporting materials
(e.g. transcripts) to:
==========================================================
Dr. Stephen C. Nodvin
National Park Service-Cooperative Park Studies Unit
Department of Forestry, Wildlife and Fisheries
The University of Tennessee
Knoxville, TN 37901-1071
Telephone: 615-974-0739
FAX: 615-974-3555
Internet: NODVIN at UTKVX.UTK.EDU
==========================================================
-- 

      Una Smith      Biology Department       smith-una@yale.edu
                     Yale University
                     New Haven, CT  06511
From: T80SMS1@NIU.bitnet
Newsgroups: bionet.jobs
Subject: Job announcement
Date: 16 Nov 92 14:56:00 GMT
Distribution: bionet


            POSITION ANNOUNCEMENTS

Northern Illinois University anticipates two
tenure-track ASSISTANT PROFESSOR positions for
fall, 1993.  A Ph.D and postdoctoral experience are
required.  Each candidate will be expected to
develop a vigorous externally funded research
program, direct graduate (M.S. and Ph.D) students,
and teach introductory courses for majors and non-
majors.

CELL BIOLOGIST:  The candidate should have research
experience in cell signal transduction, cell growth
control (oncogenes), and/or the cytoskeleton.
Teaching obligations will include an introductory
human anatomy-physiology course and a course in the
candidate's area of expertise.

EVOLUTIONARY BIOLOGIST:  The candidate should be
organismally oriented and have research experience
dealing with evolutionary aspects of physiology or
development.  The candidate's research program will
complement the department's current strengths in
evolutionary biology and ecology.  Teaching
obligations will include courses in evolution and
ecology and a course in the candidate's area of
expertise.

  Send a letter of interest, curriculum vitae,
brief statement of research goals and teaching
goals, representative reprints, and three letters
of reference by December 31, 1992 to:  Dr. Marvin
Starzyk, Chair, Department of Biological Sciences,
Northern Illinois University, DeKalb, IL 60115-
2861.  Telephone:  815-753-1753.  Northern Illinois
University is an Affirmative Action/Equal
Opportunity Employer.
Newsgroups: bionet.jobs
Subject: A postdoctoral position wanted
From: mspeek@ebc.ee (Mart Speek)
Date: 20 Nov 92 11:22:11 +0200
Keywords: Postdoctoral position
Summary: Seeking a postdoctoral position in molecular biology in CA 
X-Newsreader: TIN [version 1.1 PL6]Lines: 23

A POSTDOCTORAL POSITION in Molecular Biology WANTED

     MOLECULAR BIOLOGIST, 37, Ph.D., seeks new research post availabile
immediately or early in 1993 in California (preferably in San Francisco
Bay Area). Experience in structure and function of LINE retrotransposons
{Mol. Cell. Biol. 12, 4242-48 (1992)}. Strong technical backround (improve-
ments in DNA sequencing, cloning, ORF detection, etc) and competent in
most modern techniques used in Molecular Biology.

Contact:    Mart Speek
            Dept. of Molecular Biology
            2 Jakobi St.
            Tartu University
            Tartu EE2400
            ESTONIA (Europe)

            tel: 7-01434 35211
            fax: 7-01434 35440
            e-mail: mspeek@ebc.ee

P.S. C.V. and bibliography will be sent on request.
From: DAC050@MUVMS3.MU.WVNET.EDU
Newsgroups: bionet.jobs
Subject: (none)
Date: 17 Nov 92 17:32:00 GMT
Distribution: bionet

Please unsubscribe me from bionet.jobs news groups.

Thanks.

Dinakar
Newsgroups: bionet.jobs
From: jrichmn@ccu.umanitoba.ca (Joy Richman)
Subject: Dev Biol studentship, last chance
Organization: University of Manitoba, Winnipeg, Canada
Date: Mon, 23 Nov 1992 21:48:09 GMT

ATTENTION FINAL YEAR B.Sc. STUDENTS!!!

I have a position available in my lab (funded!!) for a M.Sc. student. I am
seeking a student interested in Developmental Biology with a B.Sc. degree
obtained in North America, Australia, New Zealand or Western Europe. 

The model system I am using is the chick embryo and I am focusing on
facial development. I have been combining both the traditional,
experimental embryo manipulation approach and the molecular approach to
elucidate the controls of facial patterning. The training I can offer in
my laboratory will prepare you for many acadmeic job opportunities. The
molecular biology of Development is fast becoming a key area of interest
being expanded in University departments around the world (see the
job advertizements in Nature and Cell). My laboratory currently
enjoys funding from the Medical Research Council of Canada and the
National Institute of Dental Research in the U.S.A. and can offer a
student many interesting projects. 

The position is available from January 1993 and the closing date for
applications is December 14th. I am also open to taking a Ph.D.
student if you have already taken a Master's degree.  


If you are interested please contact me via E-Mail. My address is
Jrichmn@ccu.umanitoba.ca 


Dr. Joy Richman
Dept. of Preventive Dental Science 
780 Bannatyne Avenue Winnipeg,
Manitoba, Canada
R3E 0W2
                                                            

Newsgroups: bionet.jobs,aus.jobs,aus.wanted,aus.mbio,monash.general
From: boutland@monu6.cc.monash.edu.au (John Boutland)
Subject: French academic seeks job, house swap
Followup-To: poster
Organization: Monash University, Melb., Australia.
Distribution: aus
Date: Wed, 18 Nov 1992 21:43:40 GMT

French assistant professor in organic chemistry at the University of
Montpellier in the south of France is interested in a job and house
swap in Australia. S/he (?) can be contacted by normal mail as follows:-

H. Choukroun,
485 Chemin des romarins,
34830 Clapiers,
France.

or email me and I will phone my daughter who also lives in Clapiers.
I can probably get an email address for her/him if anyone is interested.

John Boutland

-- 
John Boutland, Lecturer, Faculty of Computing & Information Technology,
Monash University, P.O. Box 197, CAULFIELD EAST, Victoria, Australia.
Phone (61) (3) 573 2122
Email John.Boutland@monash.edu.au
Xref: sparky bionet.jobs:652 misc.jobs.contract:4205 misc.jobs.offered:13925
From: jeremy@atlantis.CS.ORST.EDU ((-| Jeremy |-) Smith)
Newsgroups: bionet.jobs,misc.jobs.contract,misc.jobs.offered
Subject: Landscape Ecology Study of Birds in an Agroecosystem
Date: 20 Nov 92 20:08:06 GMT
Article-I.D.: leela.1992Nov20.200806.16262
Organization: Computer Science Outreach Services - Oregon State University


                    POSTDOCTORAL OPPORTUNITY


      LANDSCAPE ECOLOGY STUDY OF BIRDS IN AN AGROECOSYSTEM


Project Description:  The study is funded by the Environmental 
     Protection Agency to evaluate the effects of agricultural
     land-use patterns and practices on the avifauna of a
     midwestern agroecosystem.  The study will focus on the
     importance of various aspects of landscape structure (e.g.
     edge-to-area relationships, interspersion of habitat types,
     and connectivity of strip cover) on species richness,
     composition, abundance, and predation of artificial nests. 


Requirements: The successful applicant must have a Ph.D. or 
     equivalent in ecology or a related field, background in
     avian ecology, good quantitative skills and evidence of
     research productivity.  Knowledge of GIS and supervisory
     experience are desirable.  


Support:  Salary commensurate with experience.  Full funding for
     research expenses, including field technicians. 


Postion Duration: To begin as soon as a suitable applicant is 
     found, and perferably no later than January 1993.   Position
     to continue until spring 1995. 


Location:  Ames, Iowa


Application: Interested individuals should send a resume,
     transcripts, and letters of reference to

Dr. Louis B. Best
Department of Animal Ecology
Iowa State University
Ames, Iowa  50011
(515) 294-7477
From: cochrane@icbr.ufl.edu
Newsgroups: bionet.jobs
Subject: Two tenure-track positions
Date: 17 Nov 92 15:45:34 GMT
Organization: ICBR


  Below is a description of two tenure-track positions currently
open in our department.  Inquiries and applications are welcome.

Evolutionary Geneticist and Environmental Microbiologist.  The
University of South Florida and the Department of Biology has
two full-time, 9 month tenure-track positions at the level of
Assistant or Associate Professor.  Candidates need a Ph.D. and
postdoctoral research experience; are expected to train graduate
students and  establish research programs that are
molecularly-oriented and externally-funded.  Teaching will be
undergraduate genetics or microbiology and in specialty graduate
courses.  Intra- and interdepartmental collaboration is
facilitated through the Institute for Biomolecular Science and
the Center for Urban Ecology.  Title and salary will be
commensurate with qualifications. USF is a comprehensive
research and teaching university.  The Department is
multi-disciplinary with 35 faculty members.  Applicants should
forward a letter of intent, curriculum vitae, reprints,
statements of research and teaching interests, and should
arrange for 3 letters of recommendation to be forwarded. 
Deadline for receipt of all materials is 12/18/92.  Address 
materials to Chair of the appropriate Search Committee: 
Department of Biology, University of South Florida, Tampa,
Florida 33620-5150.

Positions are contingent upon funding.  USF is an EO/AA employer
and encourages applications from minorities and women.  If 
accommodation because of a disability is required to participate
in the application/selection process, notify the Chair in
advance.


For further information, contact Bruce Cochrane at
coch@ultrix.csc.usf.edu
From: mbgt@seqnet.daresbury.ac.uk ("G. Turner")
Newsgroups: bionet.jobs
Subject: submitting items
Date: 19 Nov 92 12:42:20 GMT
Distribution: bionet
Original-To: biojobs@uk.ac.daresbury

What is the format in which job adverts shouold be sent
to the bionet biojobs board, and to which address?
From: woodsk@ACPUB.DUKE.EDU (Krish Woods)
Newsgroups: bionet.jobs
Subject: AISES
Date: 16 Nov 92 17:51:17 GMT
Distribution: bionet

I got this name from AISESnet, and am interested in any info about jobs in the
field of biology.  I'd appreciate any help you could give me.
Thanks.
Kristi Woods