From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: afsQ1=sensory response regulator homolog, afsQ2=sensory histidine
Date: 27 Jan 93 05:59:05 GMT
Distribution: bionet
Checksum: 60778 7

LOCUS       S119098      2966 bp    DNA             BCT       19-JAN-1993
DEFINITION  afsQ1=sensory response regulator homolog, afsQ2=sensory histidine
            protein kinase homolog [Streptomyces coelicolor, A3(2), M130,
            Genomic, 2966 nt]
ACCESSION   S49777 D10654
KEYWORDS    .
SOURCE      Streptomyces coelicolor M130 A3(2)
  ORGANISM  Streptomyces coelicolor
            Unclassified.
REFERENCE   1  (bases 1 to 2966)
  AUTHORS   Ishizuka,H., Horinouchi,S., Kieser,H.M., Hopwood,D.A. and Beppu,T.
  TITLE     A putative two-component regulatory system involved in secondary
            metabolism in Streptomyces spp.
  JOURNAL   J. Bacteriol. 174, 7585-7594 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 119098] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 2.  Map location: near act gene
            cluster.
FEATURES             Location/Qualifiers
     CDS             524..1201
                     /note="GTG start codon.  sensory response regulator
                     homolog;  For the protein sequence (NCBI gibbsq 119102):
                     Method: conceptual translation supplied by author.  This
                     sequence comes from Fig. 2.
                     Author-given protein sequence differs from the conceptual
                     translation for reasons explained in citation"
                     /gene="afsQ1"
                     /product="AfsQ1"
                     /codon_start=1
                     /translation="MPSLLLIEDDEAIRTALELSLTRQGHRVATAASGEDGLKLLREQ
                     RPDLIVLDVMLPGIDGFEVCRRIRRTDQLPIILLTARNDDIDVVVGLESGADDYVVKP
                     VQGRVLDARIRAVLRRGERESTDSASFGSLVIDRSAMTVTKNGEDLQLTPTELRLLLE
                     LSRRPGQALSRQQLLRLVWEHDYLGDSRLVDACVQRLRAKVEDVPSSPTLIRTVRGVG
                     YRLDPPQ"
     CDS             1198..2805
                     /note="GTG start codon.  sensory histidine protein kinase
                     homolog;  For the protein sequence (NCBI gibbsq 119105):
                     Method: conceptual translation supplied by author.  This
                     sequence comes from Fig. 2.
                     Author-given protein sequence differs from the conceptual
                     translation for reasons explained in citation"
                     /gene="afsQ2"
                     /product="AfsQ2"
                     /codon_start=1
                     /translation="MTREHQGGTRGLAAARKGFWSGLRFTSLRLRLVLVFGLVALTAA
                     VSASGIAYWLNREAVLTRTQDAVLRDFEQEMQNRAGALPEHPTQDEVQHTAGQMANSS
                     QRFSVLLVAENADGTAVYGSSGGLGGVALSDVPESLRTAVNKEQKLTSANKHPYHLYW
                     QRITDDGTPYLVAGTKVIGGGPTGYMLKSLEPEAKDLNSLAWSLGIATALALLGSALL
                     AQALATTVLKPVHRLGVAARRLGEGKLDTRLRVSGTDELADLSRTFNSAAENLEKRVA
                     DMAGREQASRRFVADMSHELRTPLTALTAVTEVLEEELEYAGEGEGEGGSFDPMVEPA
                     VRLVVSETRRLNDLVENLMEVTRFDAGTARLVLDDVDVADQITACIDARAWLDAVDLD
                     AERGVHARLDPRRLDVILANLIGNALKHGGSPVRVSVARADHEIVIRVRDNGPGIPED
                     VLPHVFDRFYKASASRPRSEGSGLGLSIALENAHIHGGEITAENAPEGGAVFTLRLPQ
                     DPSPPADEDGGPDEETEDRGKDAKGQV"
BASE COUNT      425 a   1045 c   1075 g    421 t
ORIGIN      
        1 ctgcagcagg tcctcggcct cgaagcggtc gccggtgagg tggtaggcgg tcgcgtacag
       61 ggaggagcgg cgctcctgga cgtaggcggt gaactccgcc tccgacaggg agcggtgctc
      121 cccccggtcc cccgtgttcc ccgtctcccc cgtgttcgcg tcaaccaccg tcatgtacgc
      181 ggtgtgctga cgcccggtgc cgcgagcgca cccccgcccg ctcacggcac cggacttctc
      241 ggaaccccgg tgtgcgtgca cgtcgtgcag acgcgtgacc actgcgctgg tgttggtgcc
      301 cttcagcgtg ttcatctcgc gccccccgtc gtggactgcc ggttgcctgt gacgagaagc
      361 ctgccgcggc gacttcatgg ccgtgtccgc cgactgtcac agagctgtca caggggtccg
      421 tcaccgctgc accacccttc cttcacaggg tctggcggcg tcgtgggagc ccaaccgcac
      481 ccgcaggtcg aacaccggcc ccctcatggg ccagaatgag cgcgtgcctt ccctgttgct
      541 gatcgaggac gacgaagcca tccgtacggc cctggagctc tccctgaccc gccagggcca
      601 ccgggtggcc accgctgcca gtggtgagga cggtctgaag ctcttgcgcg agcagcggcc
      661 ggacctgatc gtgctggacg tgatgctgcc cggcatcgac ggtttcgagg tgtgccgtcg
      721 catccggcgc accgaccagc tgccgatcat tctgctgacc gcgcgcaacg acgacatcga
      781 cgtggtcgtc ggtctcgagt cgggcgccga cgactacgtc gtcaaacccg tccagggccg
      841 ggtgctcgac gcccggatcc gggccgtgct gcggcgcggg gagcgggagt ccaccgactc
      901 ggcgagcttc ggcagtctgg tcatcgaccg ttcggcgatg accgtgacga agaacggcga
      961 ggacctccag ctgacgccca ccgagctgcg gctgctcctg gagctgagcc ggcggccggg
     1021 acaggcgctg tcccggcagc agttgctgcg gctggtgtgg gagcacgact acctcggcga
     1081 ctcccggctg gtggacgcgt gcgtgcagcg gctgcgcgcc aaggtcgagg acgtgccgtc
     1141 gtccccgacc ctgatccgta ccgtgcgcgg tgtcggctac cggctggatc cgcctcagtg
     1201 acacgggaac accagggggg tacccgcggc ctggccgcgg cgcgcaaggg attctggtcc
     1261 gggctgcgct tcaccagcct gcgcctcaga ctggtcctcg tcttcggcct ggtcgcgctg
     1321 accgccgccg tgtccgcgtc cggcatcgcg tactggctga accgggaggc ggtgctgacc
     1381 cgtacccagg acgccgtgct gcgggacttc gagcaggaga tgcagaaccg ggcgggcgcg
     1441 ctgccggagc accccaccca ggacgaggtg cagcacaccg cggggcagat ggccaacagc
     1501 agccagcggt tctcggtgct gctggtcgcc gagaacgccg acggcaccgc cgtgtacggc
     1561 agttccggcg gcctgggcgg cgtcgcgctg tccgacgtgc ccgagtcgct gcgcacggcc
     1621 gtgaacaagg agcagaagct cacctcggcc aacaagcacc cgtaccacct gtactggcag
     1681 cggatcaccg acgacggcac cccgtacctg gtggccggca cgaaggtgat cggcggcggg
     1741 ccgaccggct acatgctcaa gtcgctggaa ccggaggcca aggacctgaa ctcgctcgcc
     1801 tggtcgctgg ggatcgccac cgcgctcgcc ctgctcggct ccgcgctgct cgcgcaggcc
     1861 ctggcgacga ccgtgctgaa gcccgtgcac cggctcgggg tcgcggcgcg gcggctgggc
     1921 gaggggaagc tggacacccg gctgcgggtg tccggcaccg acgaactggc cgacctgtcg
     1981 cggacgttca acagtgccgc cgagaacctg gagaagcggg tcgcggacat ggcggggcgg
     2041 gagcaggcct cgcggcgctt cgtcgcggac atgagccacg agctgcgtac gccgctgacg
     2101 gcgctcaccg cggtgacgga agtgctggag gaggagctgg agtacgcggg cgagggcgag
     2161 ggggagggcg ggagtttcga cccgatggtc gagcccgcgg tgcggctggt ggtgagcgag
     2221 acgcgacggc tgaacgacct ggtggagaac ctgatggagg tcacccgctt cgacgcgggc
     2281 accgcgcggc tggtcctgga cgacgtcgac gtcgccgacc agatcaccgc ctgcatcgac
     2341 gcccgggcct ggctggacgc cgtcgacctg gacgccgagc gcggcgtcca cgcccgcctc
     2401 gacccgcgcc ggctggacgt catcctcgcc aacctgatcg gcaacgcgct caagcacggc
     2461 gggtcgccgg tcagggtgtc cgtggcgcgg gcggaccacg agatcgtcat ccgggtgcgg
     2521 gacaacggtc ccggcatccc cgaggacgtc ctgccgcacg tcttcgaccg cttctacaag
     2581 gcgagcgcct cccggccgcg ctccgagggc agcgggctcg gtctgtccat cgccctggag
     2641 aacgcgcaca tccacggcgg tgagatcacc gcggagaacg ccccggaggg cggtgcggtg
     2701 ttcaccctgc ggctgccgca ggacccgtcg ccgcccgccg acgaggacgg cgggcccgac
     2761 gaggagaccg aggaccgggg caaggacgcg aagggacagg tctgatgacc gtacgccgtc
     2821 tgccggccct ctgcgggctg gcgacagtgg ccgtgctgct gaccgggtcg gcatccgcgc
     2881 caccgaggtg cccaccgact acggtcccgc accgtcgcgg gtgcgctgct cgctcgccga
     2941 gccgacgtgt ccgcgccacg cccggg
//