From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: D.melanogaster polyhomeotic mRNA for chromatin protein
Date: 21 Jul 92 10:04:09 GMT
Distribution: bionet
Checksum: 03546    11

LOCUS       DROPHOM      5870 bp ss-RNA             INV       21-JUL-1992
DEFINITION  D.melanogaster polyhomeotic mRNA for chromatin protein
ACCESSION   X63672
KEYWORDS    chromatin protein; polycomb group; polyhomeotic gene.
SOURCE      Drosophila melanogaster RNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 5870)
  AUTHORS   DeCamillis,M., Cheng,N., Pierre,D. and Brock,H.W.
  TITLE     The polyhomeotic gene of Drosophila encodes a chromatin protein
            that shares polytene chromosome-binding sites with polycomb
  JOURNAL   Genes Dev. 6, 223-232 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=larval; *source: tissue=imaginal disc; *source:
            clone_library=Rubin imaginal disk cDNA; *source: clone=C4-11;
            *source: chromosome=X;
            See also M64750
            From EMBL    entry DMPHOM;  dated 12-JUN-1992.
FEATURES             Location/Qualifiers
     CDS             495..5264
                     /gene="polyhomeotic"
                     /codon_start=1
                     /translation="MDRRALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPL
                     KDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGI
                     TFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPN
                     RPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYA
                     IQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPA
                     NSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGN
                     LLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTN
                     HNQSPQTVLFSPMNVISPQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQ
                     LTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQT
                     TQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQI
                     ILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQ
                     QVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTA
                     QNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVN
                     AAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQI
                     AAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVA
                     QAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQV
                     QAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSST
                     TPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVAS
                     IQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLS
                     TAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSP
                     KTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTLSKGATTPTSKQ
                     SNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVS
                     TASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANE
                     PFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLK
                     RKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEA
                     TPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSG
                     AAPKSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKH
                     LVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ"
     misc_feature    4587..4655
                     /note="Zn finger"
     polyA_signal    5569..5574
     polyA_signal    5855..5860
BASE COUNT     1704 a   1671 c   1408 g   1087 t
ORIGIN
        1 cgtacacagg tgcttagtcg ttacactgag aaaaagaaaa gtgcctgcag ccagcgggga
       61 gaagttgaag tggagtgact gtgagtggag gttgtactaa ttactactgc ccgtgcacga
      121 aacactcatt tacacgcaag cacacacaca cacacacaca cacacgagac actgggactt
      181 ttgtcggatt ttcgtattcg ttttgtgtac ttttgttgtc ttgcgttcca cgttacatac
      241 atatgtatat gtttggtgtt gcctgttgta tgtttatatt tattgccttc acacatgtgc
      301 gtgtttgtta atgtacaata taatacggca aatagcaaaa agagaagaaa ctgaggacta
      361 aaaagaaagc gccatgccga ctataacaaa aacaaccacg agtgtctccg ccgccgccga
      421 aaacaaaaac aaaacgccta agccgacgca tgcataccta taatttatta taaatattgt
      481 ttttattttg aataatggat cgtcgtgcat tgaagtttat gcaaaaaaga gcggacacag
      541 aaagcgatac gaccacaccc gtgagcacca cagcatccca ggggatttca gcatcagcga
      601 ttctagcagg aggcactctt cccttgaagg acaactcgaa catccgcgag aagcccctcc
      661 accataacta caaccacaat aacaacaaca gctcccagca ctcacactcg caccagcagc
      721 agcaacaaca gcaggtgggt ggcaagcagc tcgagcggcc actaaagtgc ctggaaacgc
      781 tcgcccagaa ggcgggaatc accttcgacg agaaatacga tgtggccagc cccccgcatc
      841 ccggcattgc ccagcagcag gcgacttcag gaacaggccc agcaacggga tcaggctcag
      901 tcacccccac aagccatcgg cacggaactc cgcccacggg ccgcaggcaa acccacaccc
      961 caagcactcc gaacaggccc agtgctccca gcacacccaa cactaactgc aactcaattg
     1021 cccgccacac cagcctcacg ctggagaagg cgcagaatcc cggccagcag gtggccgcca
     1081 ccaccacggt gccactgcag atatcccctg agcagctgca gcagttctat gcgagcaatc
     1141 cctacgccat tcaggtgaag caagagtttc ccacgcacac gaccagtggc agtggaactg
     1201 aactaaagca tgcaaccaac attatggaag ttcagcagca gttgcagctg cagcagcagc
     1261 tgtcggaagc caacggtgga ggagcagcct cggccggagc cggaggagca gctagtccgg
     1321 ccaactcgca gcaaagccag caacagcagc actccacagc catcagcacc atgtcgccga
     1381 tgcaattggc agcggccact ggaggagttg gcggggattg gacacaggga aggacggtgc
     1441 agctaatgca accctccacc agtttcctgt atccccaaat gattgtgtcg ggaaatctgt
     1501 tgcatccagg aggcctcggt cagcagccaa tccaggtgat caccgccggc aagccattcc
     1561 aaggcaacgg cccccagatg cttaccacca cgactcaaaa cgccaagcaa atgatcggtg
     1621 gccaagcggg attcgctggc ggaaattacg cgacctgcat tcccacaaac cacaatcaat
     1681 cgccccagac ggtgctcttc tcaccgatga acgtcatttc gccacagcag caacagaacc
     1741 tgctgcaatc aatggccgct gcagctcagc agcagcaact cacccaacag cagcaacagt
     1801 ttaaccagca gcaacaacag cagcttactc agcagcaaca gcagttgaca gctgctctgg
     1861 ccaaggtggg agtggatgcg cagggcaagc tggcccagaa agtggttcag aaagtgacta
     1921 ccaccagtag cgcggtccag gcggcgacgg gtcctggatc tactgggtca acacagaccc
     1981 agcaggtgca gcaggttcag caacagcagc agcagaccac ccaaaccact cagcagtgcg
     2041 tgcaggtttc acagtcgact ttgccagtcg gtgtgggtgg acagtctgtt cagactgccc
     2101 aacttctgaa cgctggccaa gcgcaacaaa tgcagattcc ctggttctta cagaatgctg
     2161 caggactgca gccgtttggg ccaaaccaga tcatcctgcg aaaccagcca gacggaaccc
     2221 aaggcatgtt cattcaacag caaccggcga cgcagacttt gcagacccag caaaaccaga
     2281 ttattcaatg caacgtgacg cagacgccca ctaaggcacg cactcaactg gatgcacttg
     2341 ctcccaagca gcaacagcag cagcagcagg ttggcactac caaccagacg cagcagcagc
     2401 aactagcggt ggctactgcc cagttgcagc aacagcagca gcaactcact gcagcagctc
     2461 tgcagcgacc aggagcccct gtcatgcccc acaatggaac tcaagtgcgt ccggccagtt
     2521 ccgtatccac acagactgcc cagaaccaga gcctgctgaa ggccaaaatg cgcaacaagc
     2581 agcagccggt gcgccccgct ttagccacat tgaaaaccga aatcggtcaa gtcgcaggac
     2641 aaaataaggt agtaggccac ctgaccaccg tgcagcagca gcaacaggcg acgaatctcc
     2701 agcaggtggt taatgcggct ggcaacaaaa tggttgtgat gagcacaacg ggcactccga
     2761 tcaccctgca gaatggacag acccttcatg cagccactgc ggcaggagtc gacaagcagc
     2821 aacagcagct acaactgttt cagaaacagc aaatcctgca acaacaacaa atgttgcaac
     2881 agcagattgc tgccattcaa atgcagcagc agcaagcggc tgttcaggcc cagcaacaac
     2941 agcagcaaca ggtctctcag cagcagcagg ttaacgccca gcaacagcaa gcggtggcgc
     3001 aacaacaaca ggcagtcgcg caggctcagc aacagcagag ggagcaacag cagcaagttg
     3061 cccaagccca ggcgcagcat caacaggctc tcgcgaatgc cactcagcaa atccttcagg
     3121 tggcgccaaa tcaattcatc acgtcccacc agcaacagca gcagcagcaa cttcacaacc
     3181 aactgataca gcagcagcta cagcaacagg cgcaggcaca agttcaagcc caagtgcagg
     3241 ctcaagcgca acagcaacaa cagcagcgag agcagcagca gaatattatc cagcagattg
     3301 tggtgcaaca gtctggagcg acttctcaac agacttccca gcagcaacag caccaccaat
     3361 ccgggcaact acagctaagt agcgtgccct tctcagtttc ttcgtcaacg acgccagccg
     3421 gaatagctac ctctagtgct ctgcaggcag ccctctccgc ctctggcgcc atctttcaga
     3481 cagctaagcc gggtacttgc agttcctcct cccccacaag cagtgtggtc acaattacca
     3541 accagagcag cactcctttg gtcaccagca gtacggtggc cagtatacag caggctcaga
     3601 cgcaatctgc tcaggtccac caacatcagc agctaatcag cgccacaatt gccggaggga
     3661 ctcaacaaca gccacaggga ccgccatcac ttacacccac cacaaatcca attttggcca
     3721 tgacctcgat gatgaatgct acagtgggtc acctttccac tgctccgcct gtaactgttt
     3781 ctgtgacaag caccgctgtt acttcgtcgc cgggtcagct ggttctctta agcacggcta
     3841 gtagcggtgg aggaggtagc ataccagcca cgcccaccaa agagacacct tcgaaagggc
     3901 ccaccgcaac cctggtgccc attggttcgc ccaagactcc tgtatcagga aaggacacct
     3961 gcactacccc caaatcatct actcctgcca ctgtcagcgc atccgtagag gccagtagtt
     4021 ccacaggcga agccctgtcc aatggagatg cctcagatag gtcttccacg ctgtcaaagg
     4081 gcgctaccac tcccaccagc aagcaaagca atgcagcagt gcagccaccg agtagcacca
     4141 ctcccaacag tgtcagtggg aaagaagagc cgaagctggc aacctgcggc agtttaacgt
     4201 ccgcaacatc aacttcaacc acgacaacga tcaccaatgg gattggagta gccagaacga
     4261 cagccagcac ggctgtctca accgctagca caaccactac cagttctggc acctttatca
     4321 caagttgcac cagcacaacc acaaccacca cgtcgagtat cagtaatgga tcgaaggatc
     4381 tccccaaggc gatgattaag ccgaacgtct taactcacgt catcgatggc ttcatcatcc
     4441 aggaggccaa cgagccattt cccgtcacca gacagcgata tgcagacaaa gacgtcagcg
     4501 atgagccgcc aaagaaaaag gcaaccatgc aggaggacat caagctaagt ggaatagcat
     4561 cagctccagg ctcggatatg gttgcttgcg agcagtgtgg aaagatggag cacaaagcaa
     4621 agctgaaacg gaagcgctac tgttcgccag gatgctcgag gcaggcaaag aacggcatcg
     4681 gtggagttgg atcaggagag acgaacggcc tggggacagg tggtatagtt ggggtggacg
     4741 ccatggcatt ggtggacagg ctggatgaag ccatggctga ggagaagatg cagacagagg
     4801 ccaccccaaa gctttcagaa tcgtttccta ttttgggagc ctcaacagaa gtacctccaa
     4861 tgtcactgcc agtccaagcg gcgatttctg cgccctcgcc tcttgcaatg cctctaggat
     4921 cgccattgtc agttgcactt ccaactcttg caccactgtc tgtagtcact tctggcgcgg
     4981 cgcccaagtc ttcggaagtg aatggaacag atcgtccgcc aatcagcagc tggagtgtgg
     5041 acgatgtcag caacttcatt cgagaactgc ctggttgtca ggactacgtg gacgacttta
     5101 tacagcagga gatcgacggc caagcgcttc tgttgctcaa ggagaagcat ttggtgaacg
     5161 ctatgggcat gaagctgggt ccagctctta aaattgtggc caaggtggag tccattaagg
     5221 aggtcccgcc acctggcgag gccaaggatc caggagcgca gtagggcagc tagagcacga
     5281 aaagccgaaa aagatgatct cctaaccgag cagtggacct ggttcaacca agtctgtcgt
     5341 gccaggtgat tctgattcaa tcgggcaggc gaaaaggacg cgaatccatt tgcaaaatat
     5401 tattagcatc aggccatcag gtcttaaacc cattgacttt gtacatactc ccaagatcac
     5461 ttataagcat attcatttat aaattaaact aacagtcaac agtcaaaaac gaatggaatt
     5521 acttaaacta aggaaaagct atgaattaat tgccagccaa gtaaatggaa taaagtacat
     5581 tttataaata agcataagtt tatagtctaa gtagcatatt aataactccc aacgtcatgg
     5641 atagtttgta caagtatttt aatcttagga atcaaatgta gcactatgat tgttctaaca
     5701 actaagaatt ttaagcctat gaataataat tgatatctaa atgtgaattt gaacttttta
     5761 ctaaataata tttgaatgcc tagacctaag cttttttttc aacatttttt ttttgcaatt
     5821 gctgaagaaa ttaaaatggc actgaatagt gtttaataaa tgtgaaaaag
//