HDTenEightyP/NetNews huggingface dataset:
From: u8951608@csdvax.csd.unsw.edu.au
Newsgroups: alt.psychoactives
Subject: Passiflora incarnata
Date: 21 Jul 92 11:45:10 +1000
Organization: University of New South Wales

The active ingredient of a new over the counter sedative in Australia is
500 mg of extract of Passion flower (Passiflora incarnata).
The manufactures seem to be incapable of supplying any real information
about it other than that.
I am particularly interested in the possibility of using it as a 
mono-amine oxidase inhibitor.
If you have any experience with this herb, or knowledge of its properties,
please let me know.

Jeremy Greenwood
jeremy@rsc3.anu.edu.au

Newsgroups: alt.psychoactives
From: bprofane@netcom.com (Gert Niewahr)
Subject: Re: Analoges of MDA
Date: Tue, 28 Jul 92 09:18:33 GMT
Organization: Netcom - Online Communication Services  (408 241-9760 guest) 

In article <k8lm#dc.rcain@netcom.com> rcain@netcom.com (Robert Cain) writes:
>Must have been bad dosage, Gert.  I used MDA many times in the '70s
>and had no negative physical unpleasantries.  Yes I was aware of 
>rubbing my teeth together, which is similar to some of the effects
>you describe, it was not even annoying.  My body felt about as good
>as I've found a substance make it feel.  Tachycardia I probably
>wouldn't have noticed.  But a feeling of deep calm is perceived
>on MDA.  I also agree that it is more intense in certain ways and
>I consider it MDMA's big brother.  Lots of similarities but some
>rather profound differences.  Fortunately my source was impeccable,
>a psychiatrist who used it clandestinely in therapy and obtained the
>finest medical grade.

I, too, had the benefit of quite pure MDA (totally unheard of these
days), cooked up in one of the best chem. departments in the
country.  I recently talked with a fellow alumnus who had the
expertise and access to check the purity of the available product;
he assured me that we were getting Ivory Snow-pure product.  The
worst I saw was product still damp with solvents.  Cutting was
verboten.

Moreover, the side effects I observed were present in many
different people ingesting many different batches of MDA.  It was a
generally accepted drawback that you'd gnaw like a beaver
through the rush and for quite a while after that.  It was a
serious thing because you wouldn't necessarily be aware that you
were chewing your lips up.

As far as body load, it was mainly in the aftereffects.  Sure, MDA
turns your corporeal being into a mass of liquid sunshine, but MDMA
gives almost that same effect without wrecking your body.  The day
after an MDA trip I was always a crip, and this was as an athletic
18-22 year-old.  MDMA has always been much easier on my body the
next day.  Shulgin doesn't make any big deal out of MDA's body
load, but it has one in my experience.
Newsgroups: alt.psychoactives
From: dw@unislc.uucp (Dan Wright)
Subject: FAQ? Or recommended books?
X-Newsreader: Tin 1.1 PL4
Organization: Unisys Corporation SLC
Date: Tue, 21 Jul 1992 20:51:49 GMT

Have the masters of this group put together a FAQ?

Are the articles archived at any site which allows ftp access?

Is there a "recommended reading" list,  you know,
of books about psychoactives which you regard as offering
safe and effective advice? 

 -- Dan Wright  "young upstart"
Newsgroups: alt.psychoactives
From: georgec@eng.umd.edu (George B. Clark)
Subject: Re: Modafinil
Date: Tue, 28 Jul 92 20:26:18 GMT
Organization: University of Maryland

In article <76713@ut-emx.uucp> oleinick@ccwf.cc.utexas.edu (Lew Oleinick) writes:

>Medline search using Modafinil as the key word.

How do you do a Medline search?  How do you subscribe to Medline? Thanks.

Newsgroups: alt.psychoactives
From: rcain@netcom.com (Robert Cain)
Subject: Re: Analoges of MDA
Date: Mon, 27 Jul 92 21:56:06 GMT
Organization: Netcom - Online Communication Services  (408 241-9760 guest) 

bprofane@netcom.com (Gert Niewahr) writes:
: In article <1740@celia.UUCP> celia!gray@usc.edu (Steve Gray) writes:
: >Regardless of neurotoxicity aspects, in my opinion, nothing beats the original
: >MDA as a high.
: >
: >Just my two tabs.
: 
: Ugh, you really enjoyed major jaw clenching, back spasms, heavy
: sweating, etc.?  Not to mention the higher incidence of
: tachycardia?  I saw more than a few folks chew their lips bloody
: without realizing it on MDA.  Yeah, the trip was more intense, but
: so were the side effects by a large degree.  Most of the people I
: did MDA with regarded the advent of MDMA as a major improvement.

Must have been bad dosage, Gert.  I used MDA many times in the '70s
and had no negative physical unpleasantries.  Yes I was aware of 
rubbing my teeth together, which is similar to some of the effects
you describe, it was not even annoying.  My body felt about as good
as I've found a substance make it feel.  Tachycardia I probably
wouldn't have noticed.  But a feeling of deep calm is perceived
on MDA.  I also agree that it is more intense in certain ways and
I consider it MDMA's big brother.  Lots of similarities but some
rather profound differences.  Fortunately my source was impeccable,
a psychiatrist who used it clandestinely in therapy and obtained the
finest medical grade.

Bob

-- 
Bob Cain    rcain@netcom.com   408-358-2007

Stomp out intolerance!
From: sg@monsoon.com (Sunil Gupta)
Newsgroups: alt.psychoactives
Subject: Pharmaceutical Availability
Date: Tue, 21 Jul 92 12:31:57 EDT
Organization: Monsoon Software, Inc.

I am considering starting a regimen of Piracetam and Hydergine
along with Ginkgo Biloba and Vasopressin. Unfortunately, it's
been tough going to find a source for these substances. I would
appreciate any pointers to sources (phone numbers AND addresses,
please).

Sunil Gupta
Monsoon Software, Inc.
sg@monsoon.com
Newsgroups: alt.psychoactives
From: dyer@spdcc.com (Steve Dyer)
Subject: Re: natural sources of lithium?
Organization: S.P. Dyer Computer Consulting, Cambridge MA
Distribution: na
Date: Tue, 28 Jul 1992 04:01:12 GMT

In article <1992Jul25.044218.8680@microsoft.com> jeffc@microsoft.com (Jeff Carey) writes:
>Are there naturally occurring plants, or other food sources, of lithum
>that would be a reasonable substitute for low-level lithium therapy?

No.

If you need to take lithium, you should only be taking predictable
doses under your doctor's supervision, and with blood levels taken
on a regular basis to avoid undue toxicity.  Lithium has a "therapeutic
window" in which it is effective--too little doesn't have any effect,
too much can be toxic.


-- 
Steve Dyer
dyer@ursa-major.spdcc.com aka {ima,harvard,rayssd,linus,m2c}!spdcc!dyer
From: u8951608@csdvax.csd.unsw.edu.au
Newsgroups: alt.psychoactives
Subject: Re: Analoges of MDA
Date: 23 Jul 92 15:33:34 +1000
Organization: University of New South Wales

In article <35899@sdcc12.ucsd.edu>, tcederqu@sdcc13.ucsd.edu (Trevor Cederquist) writes:
>>>Are you sure that MMDA is in this category, wrt chemistry, 
>>>toxicity, and activity?
> 
> BTW, I believe MMDA DOES belong in this category. 

Which one of the three? I thought that it was originally referred to
inappropriately by chemical structure; it is methoxy methylenedioxy
amphetamine, isn't it? Presumably produced by aminating myristicin. 
Also, activity: It is somewhat different to MDA and certainly MDMA, 
is it not? In terms of neurotoxicity, I am not at all surprised
to learn that it belongs in this category. What other amphetamines
have been tested for neurotoxicity? I have heard of p-Cl amphetamine
in this regard.

Jeremy
jeremy@rsc3.anu.edu.au

Newsgroups: alt.psychoactives
From: lever@voyager.corp.sgi.com (Karen Lever)
Subject: Free Classes in Tantric Meditation
Followup-To: poster
Originator: root@voyager.corp.sgi.com
Keywords: consciousness, meditation, Enlightenment
Organization: Silicon Graphics, Inc.
Distribution: ba
Date: Thu, 30 Jul 1992 08:49:27 GMT

Free intensive workshops will be offered in the Bay Area:

Stanford University                       U.C. Berkeley
    Thursday, July 30                         Monday, August 3
    Thursday, August 6                        


Topics include: Meditation, Buddhism, Power, Balance, Wisdom,
Enlightenment, Personal Happiness, Reincarnation, Career Success
and Miracles.  Classes consist of discussion and meditation, 
and are designed for individuals age 29 and under. 

Stanford classes will be held in the Escondido Village Center 
(next to the E.V. office), from 7:30 to 9:30 p.m.

U.C. Berkeley classes will be held in Wheeler Hall, Room 223,
from 7:30 to 9:30 p.m.

Additional classes will be offered in the Bay Area this summer
and fall.  For information, please call 415-995-4721.
From: hughes@gary.enet.dec.com (Gary Hughes - VMS Development)
Newsgroups: alt.psychoactives
Subject: Re: Analoges of MDA
Date: 24 Jul 92 17:18:51 GMT
Organization: Digital Equipment Corporation


Back to the tetralin/indan analogue thread...

So tetralin is tetrahydroxy-napthalene, a bicyclic with one ring aromatic, one
not. Does a tetralin analogue of MDA have the methylenedioxy ring and the
isopropylamine chain still attached to the aromatic ring, leaving the other
ring untouched? Or are we talking about substitution on the other ring?

Presumably the same answers will apply to the indan analogue?

gary
From: oleinick@ccwf.cc.utexas.edu (Lew Oleinick)
Newsgroups: alt.psychoactives
Subject: Modafinil
Date: 28 Jul 92 19:43:54 GMT
Reply-To: oleinick@ccwf.cc.utexas.edu (Lew Oleinick)
Organization: The University of Texas at Austin, Austin TX
Originator: oleinick@thumper.cc.utexas.edu

Hi all.  I've been doing a little Medline searching on
Modafinil and have found a number of interesting articles
which claim that it is a safe and effective (non-addicting)
stimulant (although the articles tend to lable it as
a "cognition enhancer" rather than as a stimulant).  My
question is for those overseas or in Mexico.  I'd like
to know if it is available in your country and if so, 
under what trade name and for how much does it retail.
For further information I recommend performing your own
Medline search using Modafinil as the key word.
Thanks,
-- Lew
From: norman@Software.Mitel.COM (Norm McMillan)
Newsgroups: alt.psychoactives
Subject: pharmacology and ethnobotany of acorus calamus
Date: 28 Jul 92 14:40:06 GMT
Followup-To: Norman@Software.Mitel.COM
Distribution: na
Organization: Mitel. Kanata (Ontario). Canada.


hi ... i would appreciate recieving any information about acorus calamus ... 
toxicology, mythology, tales of usage, chemical analysis, uses, list of active
ingredients, medical dope, derivatives identified/used, etc ...

thanks in advance for all yer help ...

curious normie
From: lamontg@milton.u.washington.edu (Lamont Granquist)
Newsgroups: alt.psychoactives
Subject: Re: Analoges of MDA
Date: 22 Jul 92 21:47:53 GMT
Organization: 'Operation: Mindcrime'

u8951608@csdvax.csd.unsw.edu.au writes:
>In article <lamontg.711060751@milton>, lamontg@milton.u.washington.edu (Lamont Granquist) writes:
>> amessing@willamette.edu (Adam Messinger) writes:
>>>I know that in addition to the methyl analog of MDA, the ethyl and other
>>>analogs are also active.  In light of the established neurotoxicity of
>>>MDMA, does any one know or is at least willing to hazard a guess at the 
>>>toxicity of the variou analoges.
>> 
>> All of the methylenedioxyphenyl bicyclic empathogens that have been
>> tested for neurotoxicity have been shown to be neurotoxic -- off the top
>> of my head, MDMA, MDA and MMDA are the three I know of.  The tricyclic
>                            ^^^^
>Are you sure that MMDA is in this category, wrt chemistry, 
>toxicity, and activity?

Yup.  Its (racking my brain... something like...) 3,4-methylenedioxy-5-
methoxyamphetamine.  I believe thats correct because Shulgin was trying to
fuse the 3 and 4-methoxy groups of TMA into a methylenedioxy ring
when he synthesized it.  And its definitely empathogenic, and I'm almost
positive I read that it was shown to be neurotoxic in the same manner as
MDMA and MDA.  MDE is another one I think I read was also neurotoxic.

>> tetralin and indan analogues MDAI and MDMI have been tested, however and shown
>> to not be neurotoxic.  I've posted about these in the past -- I don't
>> have the reference here, but a Medline search on 'Nichols and indan' should
>> turn up the citation.
>> 
>> Apparently these are an utter hellacious bitch to synthesize according to
>> someone on the net -- harder than LSD.  Anyone care to comment as to if
>> this is true?
>
>Well, if I had a good enough lab and the appropriate precursors, and
>plenty of time, I could make either. The tetralins are maybe an
>extra step or two from memory. Making the tetralins would not only
>be legal (at least in Australia) but would be far less likely to
>arouse suspicion, since the precursors are less obvious. But
>obtaining the correct precursors would still be tricky.
>It is virtually unthinkable that anyone without a fair bit of
>experience in chemistry, a lot of time, determination and cash, access
>to excellent contacts and a good lab and chemicals could make either.

I heard that they were much harder.

-- 
Lamont Granquist  lamontg@u.washington.edu  (anon: ap.2187@cupid.sai.com)
University of Washington, Seattle.    Disc: if UW ever finds out what I post... 
alt.drugs FTP site: ftp.u.washington.edu[128.95.136.1] dir:/public/alt.drugs
               For quotes and other useless info see my .plan
Newsgroups: alt.psychoactives
From: eesnyder@boulder.Colorado.EDU (Eric E. Snyder)
Subject: Re: pharmacology and ethnobotany of acorus calamus
Organization: University of Colorado, Boulder
Distribution: na
Date: 30 Jul 92 17:11:53 GMT

locklin@henry.ece.cmu.edu (Scott Locklin) writes:

>The active ingredient is an amphetamine precursor called arasone...
>The old men of the cree indian tribe use this root for its stimulating
>effects... Supposedly it makes you hallucinate; I wouldn't try it 
>myself (why did the cree give it to their OLD men?)

_Acorus calamus_ contains asarones; I have never heard of arasone.  
I would not consider asarone an amphetamine precursor since the 
aromatic ring is 1,2,4-trimethoxy- substituted.  It does however 
make a fine precursor for a number of interesting phenylethylamine
and phenylisopropylamine psychedelics.  

---------------------------------------------------------------------------
TTGATTGCTAAACACTGGGCGGCGAATCAGGGTTGGGATCTGAACAAAGACGGTCAGATTCAGTTCGTACTGCTG
Eric E. Snyder                            
Department of MCD Biology              ...making feet for childrens' shoes.
University of Colorado, Boulder   
Boulder, Colorado 80309-0347
LeuIleAlaLysHisTrpAlaAlaAsnGlnGlyTrpAspLeuAsnLysAspGlyGlnIleGlnPheValLeuLeu
---------------------------------------------------------------------------
Newsgroups: alt.psychoactives
From: lamontg@milton.u.washington.edu (Lamont Granquist)
Subject: Re: Analoges of MDA
Organization: 'Operation: Mindcrime'
Date: Fri, 31 Jul 1992 00:41:43 GMT

I and my friend both tried MDA from the same batch.  I got *NO* jaw clentching,
back problems, etc, etc.  He got jaw clentching, and nausea along with some
other amphetamine-like body loading effects.

different drugs effect different people in different ways.

-- 
Lamont Granquist  lamontg@u.washington.edu  (anon: ap.2187@cupid.sai.com)
University of Washington, Seattle.    Disc: if UW ever finds out what I post... 
alt.drugs FTP site: ftp.u.washington.edu[128.95.136.1] dir:/public/alt.drugs
               For quotes and other useless info see my .plan
Newsgroups: alt.psychoactives
From: georgec@eng.umd.edu (George B. Clark)
Subject: Re: "Smart Drugs and Nutrients"
Date: Thu, 30 Jul 92 12:44:45 GMT
Organization: University of Maryland

In article <613ooB3w164w@infopls.chi.il.us> zane@infopls.chi.il.us (Sameer Parekh) writes:
>        How's the book "Smart Drugs and Nutrients"? Useful? factual? Full 
>of errors? A friend of mine in planning some taking of smart drugs, and 
>so as a second choice when buying some books I chose that.. and I got it. 
> So I'm probably going to sell it to him, and it'd be helpful to also 
>tell him what parts to avoid, etc.

The book is mostly sensational claims and personal testimonials with little
merit. Personal testimonials have no merit because they do not carry
the validity of a good double-blind test. 

Also, forget about the two foreign mailorder pharmacies listed in the
appendix. Given the FDA's crackdown on smart drugs, and because of their
publicity as a result of this book, these two companies are no longer
reliable.

Certain other foreign pharmacies are reliable, but I don't feel like
mentioning them, since you'd be wasting your money, anyway.

To do smart drugs "correctly," you have to spend the equivalent of
several dollars per day. Even then, results, if any, become apparent
only after many weeks of continuous use.

I know two MDs in the USA who are strong proponents of smart drugs. Both
are quacks. That is, everything they endorse, including stuff other than
smart drugs, contradicts mainstream medicine.
From: gray@celia.UUCP (Steve Gray)
Newsgroups: alt.psychoactives
Subject: Re: Analoges of MDA
Date: 27 Jul 92 04:32:17 GMT
Reply-To: celia!gray@usc.edu (Steve Gray)
Organization: Rhythm & Hues, Inc., Hollywood

Regardless of neurotoxicity aspects, in my opinion, nothing beats the original
MDA as a high.

Just my two tabs.
Newsgroups: alt.psychoactives
From: jan_b@lysator.liu.se (Jan Besehanic)
Subject: Medline? Via telnet, perhaps??
Summary: none what so ever, apart from the fact that I want info on Medline
Keywords: Allah, Black September, nootropics, psychoactives, NSA
Organization: Lysator Academic Computer Club, Linkoping University, Sweden
Date: Thu, 30 Jul 1992 09:20:26 GMT

Hi there all you happy nootropics addicts.

A simple question;
Can I access Medline via telnet? If not, what ways are there of
accessing Medline apart from actually dialing in?

I can dial in directly to Medline, but I'd rather not since I'm 
actually located on another continent with a fascist telephone company
that has recently shut down the blueboxing facilities, but that's another
story...

May your neurotransmitters never fail you,

Jan


--
Jan Besehanic
email: jan_b@lysator.liu.se
New, improved .sig-file under construction.

Newsgroups: alt.psychoactives
From: lamontg@milton.u.washington.edu (Lamont Granquist)
Subject: Re: Analoges of MDA
Organization: 'Operation: Mindcrime'
Date: Fri, 24 Jul 1992 08:13:19 GMT

u8951608@csdvax.csd.unsw.edu.au writes:
>Which one of the three? I thought that it was originally referred to
>inappropriately by chemical structure; it is methoxy methylenedioxy
>amphetamine, isn't it?

I was referring to bicyclic methylenedioxyphenyl compounds.  If MMDA
isn't one of those, what is it?  My point was that all the empathogens
that have those two rings that have been tested were neurotoxic.  MMDA
does have those two rings, just plus that methoxy sticking down.

>Presumably produced by aminating myristicin. 

Bingo.

>Also, activity: It is somewhat different to MDA and certainly MDMA, 
>is it not?

MDA is somewhat different than MDMA
MDE is somewhat different than MDMA
MDA is somewhat different than MDE
MMDA is somewhat different than MDMA
MMDA is somewhat different than MDA
MMDA is somewhat different than MDE

Where do you draw the line?  What subjective quality is important and in what
amount?  IMHO I'd place them all in the empathogenic/entactogenic group as
opposed to psychedelics/hallucinogens/dissasociatives/stimulants/etc 

> In terms of neurotoxicity, I am not at all surprised
>to learn that it belongs in this category. What other amphetamines
>have been tested for neurotoxicity? I have heard of p-Cl amphetamine
>in this regard.

*shrug* offhand I don't have them all memorized.  I've got 200 pages of
disorganized MDMA neurotoxicity crap though.  Something is probably in there
somewhere...

-- 
Lamont Granquist  lamontg@u.washington.edu  (anon: ap.2187@cupid.sai.com)
University of Washington, Seattle.    Disc: if UW ever finds out what I post... 
alt.drugs FTP site: ftp.u.washington.edu[128.95.136.1] dir:/public/alt.drugs
               For quotes and other useless info see my .plan
Newsgroups: alt.psychoactives
From: bprofane@netcom.com (Gert Niewahr)
Subject: Re: Analoges of MDA
Date: Mon, 27 Jul 92 18:38:07 GMT
Organization: Netcom - Online Communication Services  (408 241-9760 guest) 

In article <1740@celia.UUCP> celia!gray@usc.edu (Steve Gray) writes:
>Regardless of neurotoxicity aspects, in my opinion, nothing beats the original
>MDA as a high.
>
>Just my two tabs.

Ugh, you really enjoyed major jaw clenching, back spasms, heavy
sweating, etc.?  Not to mention the higher incidence of
tachycardia?  I saw more than a few folks chew their lips bloody
without realizing it on MDA.  Yeah, the trip was more intense, but
so were the side effects by a large degree.  Most of the people I
did MDA with regarded the advent of MDMA as a major improvement.
From: pck@acsu.buffalo.edu (Philip C. Kilinskas)
Newsgroups: alt.psychoactives
Subject: Re: Analoges of MDA
Date: 21 Jul 92 16:10:45 GMT
Organization: UB

u8951608@csdvax.csd.unsw.edu.au writes:

>In article <lamontg.711060751@milton>, lamontg@milton.u.washington.edu (Lamont Granquist) writes:
>> amessing@willamette.edu (Adam Messinger) writes:
>>>I know that in addition to the methyl analog of MDA, the ethyl and other
>>>analogs are also active.  In light of the established neurotoxicity of
>>>MDMA, does any one know or is at least willing to hazard a guess at the 
>>>toxicity of the variou analoges.
>> 
>> All of the methylenedioxyphenyl bicyclic empathogens that have been
>> tested for neurotoxicity have been shown to be neurotoxic -- off the top
>> of my head, MDMA, MDA and MMDA are the three I know of.  The tricyclic
>                            ^^^^
>Are you sure that MMDA is in this category, wrt chemistry, 
>toxicity, and activity?

I think it's a bit unfair to refer to these substances as neurotoxic without
mentioning that the doses done in the experiments I read about were 
10mg/kg or 15mg/kg, which would translate to doses of 600-1500mg in humans,
quite a number of times over the usual dose of 100-120mg.  I'm sure there are
a lot of drugs we could take and multiply the dosage tenfold and find some
resulting damage.

Phil
____________________________________________________________________________
pck@acsu.buffalo.edu /  "Our days are like grass..." - Psalms 103:51
Your eyes are weary from staring at the CRT.  You feel sleepy.  Notice how
restful it is to watch the cursor blink.  Close your eyes.  The opinions
stated above are yours.  You cannot imagine why you ever felt otherwise.