From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human interferon-induced cellular resistance mediator protein (MxB)
Date: 5 Nov 92 23:10:52 GMT
Distribution: bionet
Checksum: 34632 6

LOCUS       HUMMXB       2961 bp ss-mRNA            PRI       15-MAR-1990
DEFINITION  Human interferon-induced cellular resistance mediator protein (MxB)
            mRNA, complete cds.
ACCESSION   M30818
KEYWORDS    interferon-induced cellular resistance mediator protein;
            interferon-induced protein.
SOURCE      Human IFN-alpha-2 treated cell line T98G, cDNA to mRNA, clone Mx8.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2961)
  AUTHORS   Aebi,M., Faeh,J., Hurt,N., Samuel,C.E., Thomis,D.C., Bazzigher,L.,
            Pavlovic,J., Haller,O. and Staeheli,P.
  TITLE     cDNA structures and regulation of two interferon-induced human Mx
            proteins
  JOURNAL   Mol. Cell. Biol. 9, 5062-5072 (1989)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            <1..2961
                     /note="MxB mRNA"
     CDS             105..2252
                     /product="interferon-induced Mx protein"
                     /codon_start=1
                     /translation="MSKAHKPWPYRRRSQFSSRKYLKKEMNSFQQQPPPFGTVPPQMM
                     FPPNWQGAEKDAAFLAKDFNFLTLNNQPPPGNRSQPRAMGPENNLYSQYEQKVRPCID
                     LIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLK
                     KQPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEV
                     PDLTIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEAL
                     SMAHEVDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEIT
                     NRLSLAEATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQ
                     IRESHQKATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGEEVVRENETRL
                     YNKIREDFKNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQY
                     IQQLVEPALSMLQKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAEN
                     MIQLQFRMEQMVFCQDQIYSVVLKKVREEIFNPLGTPSQNMKLNSHFPSNESSVSSFT
                     EIGIHLNAYFLETSKRLANQIPFIIQYFMLRENGDSLQKAMMQILQEKNRYSWLLQEQ
                     SETATKRRILKERIYRLTQARHALCQFSSKEIH"
BASE COUNT      826 a    754 c    721 g    660 t
ORIGIN      158 bp upstream of TaqI site.
        1 aagagatgat ttctccatcc tgaacgtgca gcgagcttgt caggaagatc ggaggtgcca
       61 agtagcagag aaagcatccc ccagctctga cagggagaca gcacatgtct aaggcccaca
      121 agccttggcc ctaccggagg agaagtcaat tttcttctcg aaaatacctg aaaaaagaaa
      181 tgaattcctt ccagcaacag ccaccgccat tcggcacagt gccaccacaa atgatgtttc
      241 ctccaaactg gcagggggca gagaaggacg ctgctttcct cgccaaggac ttcaactttc
      301 tcactttgaa caatcagcca ccaccaggaa acaggagcca accaagggca atggggcccg
      361 agaacaacct gtacagccag tacgagcaga aggtgcgccc ctgcattgac ctcatcgact
      421 ccctgcgggc tctgggtgtg gagcaggacc tggccctgcc agccatcgcc gtcatcgggg
      481 accagagctc gggcaagagc tctgtgctgg aggcactgtc aggagtcgcg cttcccagag
      541 gcagcggaat cgtaaccagg tgtccgctgg tgctgaaact gaaaaagcag ccctgtgagg
      601 catgggccgg aaggatcagc taccggaaca ccgagctaga gcttcaggac cctggccagg
      661 tggagaaaga gatacacaaa gcccagaacg tcatggccgg gaatggccgg ggcatcagcc
      721 atgagctcat cagcctggag atcacctccc ctgaggttcc agacctgacc atcattgacc
      781 ttcccggcat caccagggtg gctgtggaca accagccccg agacatcgga ctgcagatca
      841 aggctctcat caagaagtac atccagaggc agcagacgat caacttggtg gtggttccct
      901 gtaacgtgga cattgccacc acggaggcgc tgagcatggc ccatgaggtg gacccggaag
      961 gggacaggac catcggtatc ctgaccaaac cagatctaat ggacaggggc actgagaaaa
     1021 gcgtcatgaa tgtggtgcgg aacctcacgt accccctcaa gaagggctac atgattgtga
     1081 agtgccgggg ccagcaggag atcacaaaca ggctgagctt ggcagaggca accaagaaag
     1141 aaattacatt ctttcaaaca catccatatt tcagagttct cctggaggag gggtcagcca
     1201 cggttccccg actggcagaa agacttacca ctgaactcat catgcatatc caaaaatcgc
     1261 tcccgttgtt agaaggacaa ataagggaga gccaccagaa ggcgaccgag gagctgcggc
     1321 gttgcggggc tgacatcccc agccaggagg ccgacaagat gttctttcta attgagaaaa
     1381 tcaagatgtt taatcaggac atcgaaaagt tagtagaagg agaagaagtt gtaagggaga
     1441 atgagacccg tttatacaac aaaatcagag aggattttaa aaactgggta ggcatacttg
     1501 caactaatac ccaaaaagtt aaaaatatta tccacgaaga agttgaaaaa tatgaaaagc
     1561 agtatcgagg caaggagctt ctgggatttg tcaactacaa gacatttgag atcatcgtgc
     1621 atcagtacat ccagcagctg gtggagcccg cccttagcat gctccagaaa gccatggaaa
     1681 ttatccagca agctttcatt aacgtggcca aaaaacattt tggcgaattt ttcaacctta
     1741 accaaactgt tcagagcacg attgaagaca taaaagtgaa acacacagca aaggcagaaa
     1801 acatgatcca acttcagttc agaatggagc agatggtttt ttgtcaagat cagatttaca
     1861 gtgttgttct gaagaaagtc cgagaagaga tttttaaccc tctggggacg ccttcacaga
     1921 atatgaagtt gaactctcat tttcccagta atgagtcttc ggtttcctcc tttactgaaa
     1981 taggcatcca cctgaatgcc tacttcttgg aaaccagcaa acgtctcgcc aaccagatcc
     2041 catttataat tcagtatttt atgctccgag agaatggtga ctccttgcag aaagccatga
     2101 tgcagatact acaggaaaaa aatcgctatt cctggctgct tcaagagcag agtgagaccg
     2161 ctaccaagag aagaatcctt aaggagagaa tttaccggct cactcaggcg cgacacgcac
     2221 tctgtcaatt ctccagcaaa gagatccact gaagggcggc gatgcctgtg gttgttttct
     2281 tgtgcgtact cattcattct aaggggagtc ggtgcaggat gccgcttctg ctttggggcc
     2341 aaactcttct gtcactatca gtgtccatct ctactgtact ccctcagcat cagagcatgc
     2401 atcaggggtc cacacaggct cagctctctc caccacccag ctcttccctg accttcacga
     2461 agggatggct ctccagtcct tgggtcccgt agcacacagt tacagtgtcc taagatactg
     2521 ctatcattct tcgctaattt gtatttgtat tcccttcccc ctacaagatt atgagacccc
     2581 agagggggaa ggtctgggtc aaattcttct tttgtatgtc cagtctcctg cacagcacct
     2641 gcagcattgt aactgcttaa taaatgacat ctcactgaac gaatgagtgc tgtgtaagtg
     2701 atggagatac ctgaggctat tgctcaagcc caggccttgg acatttagtg actgttagcc
     2761 ggtccctttc agatccagtg gccatgcccc ctgcttccca tggttcactg tcattgtgtt
     2821 tcccagcctc tccactcccc cgccagaaag gagcctgagt gattctcttt tcttcttgtt
     2881 tccctgatta tgatgagctt ccattgttct gttaagtctt gaagaggaat ttaataaagc
     2941 aaagaaactt tttaaaaacg t
//