From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for interleukin 2/BCM fusion protein
Date: 29 Dec 92 01:19:40 GMT
Distribution: bionet
Checksum: 58440 4

LOCUS       HUMIL2BCM    1073 bp ss-RNA             PRI       07-DEC-1992
DEFINITION  H.sapiens mRNA for interleukin 2/BCM fusion protein
ACCESSION   Z14955
KEYWORDS    BCM gene; fusion protein; interleukin 2.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Laabi,Y., Gras,M.P., Carbonnel,F., Brouet,J.C., Berger,R.,
            Larsen,C.J. and Tsapis,A.
  TITLE     A new gene, BCM, on chromosome 16 is fused to the interleukin 2
            gene by a t(4;16)(q26;p13) translocation in a malignant T-cell
            lymphoma
  JOURNAL   EMBO J. 11, 3897-3904 (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=Ganglion; *source: cell_type=T-cell; *source:
            is_macronuclear=N; *source: is_proviral=N; *source: is_germline=N;

               From EMBL    entry HSIL2BCM;  dated 21-OCT-1992.
FEATURES             Location/Qualifiers
     misc_feature    <1..321
                     /note="three first exons of interleukin 2 gene"
     misc_feature    322..864
                     /note="BCM gene"
     CDS             <1..867
                     /product="interleukin 2/BCM fusion protein"
                     /codon_start=1
                     /translation="ALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNP
                     KLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVI
                     VLELKMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAIL
                     WTCLGLSLIISLAVFVLMFLLRKISSEPLKDEFKNTGSGLLGMANIDLEKSRTGDEII
                     LPRGLEYTVEECTCEDCIKSKPKVDSDHCFPLPAMEEGATILVTTKTNDYCKSLPAAL
                     SATEIEKSISAR"
BASE COUNT      325 a    217 c    222 g    309 t
ORIGIN      
        1 gcactaagtc ttgcacttgt cacaaacagt gcacctactt caagttctac aaagaaaaca
       61 cagctacaac tggagcattt actgctggat ttacagatga ttttgaatgg aattaataat
      121 tacaagaatc ccaaactcac caggatgctc acatttaagt tttacatgcc caagaaggcc
      181 acagaactga aacatcttca gtgtctagaa gaagaactca aacctctgga ggaagtgcta
      241 aatttagctc aaagcaaaaa ctttcactta agacccaggg acttaatcag caatatcaac
      301 gtaatagttc tggaactaaa gatggctggg cagtgctccc aaaatgaata ttttgacagt
      361 ttgttgcatg cttgcatacc ttgtcaactt cgatgttctt ctaatactcc tcctctaaca
      421 tgtcagcgtt attgtaatgc aagtgtgacc aattcagtga aaggaacgaa tgcgattctc
      481 tggacctgtt tgggactgag cttaataatt tctttggcag ttttcgtgct aatgtttttg
      541 ctaaggaaga taagctctga accattaaag gacgagttta aaaacacagg atcaggtctc
      601 ctgggcatgg ctaacattga cctggaaaag agcaggactg gtgatgaaat tattcttccg
      661 agaggcctcg agtacacggt ggaagaatgc acctgtgaag actgcatcaa gagcaaaccg
      721 aaggtcgact ctgaccattg ctttccactc ccagctatgg aggaaggcgc aaccattctt
      781 gtcaccacga aaacgaatga ctattgcaag agcctgccag ctgctttgag tgctacggag
      841 atagagaaat caatttctgc taggtaatta accatttcga ctcgagcagt gccactttaa
      901 aaatcttttg tcagaataga tgatgtgtca gatctcttta ggatgactgt atttttcagt
      961 tgccgataca gctttttgtc ctctaactgt ggaaactctt tatgttagat atatttctct
     1021 aggttactgt tgggagctta atggtagaaa cttccttggt ttctatgatt aaa
//