From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Pseudorabies virus (PRV) protein kinase gene, complete cds.
Date: 29 Jul 92 10:03:51 GMT
Distribution: bionet
Checksum: 25264     5

LOCUS       SH1PK        1403 bp ds-DNA             VRL       29-JUL-1992
DEFINITION  Pseudorabies virus (PRV) protein kinase gene, complete cds.
ACCESSION   D10451 D01116
KEYWORDS    protein kinase; unique short region.
SOURCE      Pseudorabies virus (strain NIA-3) (library: pN3HB) DNA.
  ORGANISM  Suid herpesvirus 1
            Viridae; ds-DNA enveloped viruses; Herpesviridae;
            Alphaherpesvirinae.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   van Zijl,M., van der Gulden,H., de Wind,N., Gielkens,A. and
            Berns,A.
  TITLE     Identification of two genes in the unique short region of
            pseudorabies virus; comparison with herpes simplex virus and
            varicella-zoster virus
  JOURNAL   J. Gen. Virol. 71, 1747-1755 (1990)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     repeat_region   <1..12
                     /rpt_type=inverted
                     /note="internal repeat"
     misc_feature    13..>1403
                     /note="unique short region (Us) of PRV genome"
     misc_feature    99
                     /note="minor transcriptional start site"
     CDS             163..1335
                     /note="minor fraction (<5%)"
                     /product="protein kinase"
                     /gene="PK"
                     /codon_start=1
                     /translation="MLAMWRWVTKRSRLRRGHAHLGGNKGVRGICSLYLAGLSRGLSR
                     VHAQRSHAATMADAGIPDEILYSDISDDEIIIDGDGDGDSSGDEDDDDGGLTRQAASR
                     IATDLGFEVLQPLQSGSEGRVFVARRPGEADTVVLKVGQKPSTLMEGMLLKRLAHDNV
                     MSLKQMLARGPVTCLVLPHFRCDLYSYLTMRDGPLDMRDAGRVIRSVLRGLAYLHGMR
                     IMHRDVKAENIFLEDVDTVCLGDLGAARCNVAAPNFYGLAGTIETNAPEVLARDRYDT
                     KVDVWGAGVVLFETLAYPKTIAGGDEPAINGEMHLIDLIRALGVHPEEFPPDTRLRSE
                     FVRYAGTHRQPYTQYARVARLGLPETGAFLIYKMLTFDPVRRPSADEILNFGMWTV"
     misc_feature    258
                     /note="major transcriptional start site"
     misc_feature    260
                     /note="major transcriptional start site"
     misc_feature    261
                     /note="major transcriptional start site"
     CDS             325..1335
                     /note="major fraction (>95%)"
                     /product="protein kinase"
                     /gene="PK"
                     /codon_start=1
                     /translation="MADAGIPDEILYSDISDDEIIIDGDGDGDSSGDEDDDDGGLTRQ
                     AASRIATDLGFEVLQPLQSGSEGRVFVARRPGEADTVVLKVGQKPSTLMEGMLLKRLA
                     HDNVMSLKQMLARGPVTCLVLPHFRCDLYSYLTMRDGPLDMRDAGRVIRSVLRGLAYL
                     HGMRIMHRDVKAENIFLEDVDTVCLGDLGAARCNVAAPNFYGLAGTIETNAPEVLARD
                     RYDTKVDVWGAGVVLFETLAYPKTIAGGDEPAINGEMHLIDLIRALGVHPEEFPPDTR
                     LRSEFVRYAGTHRQPYTQYARVARLGLPETGAFLIYKMLTFDPVRRPSADEILNFGMW
                     TV"
     CDS             1395..>1403
                     /product="glycoprotein gX"
                     /codon_start=1
                     /translation="MKW"
BASE COUNT      237 a    486 c    472 g    208 t
ORIGIN
        1 gggcggcggc gcccccgtcg cggtcgagaa ccaccgccgc cgtcaccgcc gcctcccacc
       61 cgatgtgata tcgcggcacg ccggccgtcc cggcgctcat tcacaccgca cccgttcgcc
      121 cacgtccccg cgggcaagca cgcacacacc cggtcgcgca tcatgctggc gatgtggaga
      181 tgggtcacca agaggtcgcg gctccgccga ggccacgccc atcttggggg aaataaagga
      241 gtccggggaa tttgttcctt ataccttgcc gggctcagca gggggttgtc gcgcgtccac
      301 gcccagcgct cgcacgcagc aacaatggcc gacgccggaa tccccgacga gatcctgtac
      361 tcggacatca gcgacgacga gatcatcatc gacggcgacg gcgacggcga cagcagcggg
      421 gacgaggacg acgatgacgg ggggctgacg cggcaggccg cgtcgcgcat cgccacggac
      481 ctgggcttcg aggtgctgca gcccctgcag tcgggctcgg agggccgcgt cttcgtggcc
      541 cgccggcccg gcgaggcgga cacggtggtg ctgaaggtgg gccagaagcc ctcgacgctg
      601 atggagggca tgctgctgaa gcgcctggcc cacgataacg tcatgagcct gaagcagatg
      661 ctcgcccggg gcccggtgac gtgcctggtc ctgccgcact ttcggtgcga tctgtacagc
      721 tacctgacca tgcgggacgg gccgctggac atgcgcgacg ccgggcgcgt gatccggtcc
      781 gtgctccgcg ggctcgccta cctgcacggg atgcgcatca tgcaccgcga cgtcaaggcg
      841 gagaacatct tcctcgagga cgtggacacg gtgtgcctgg gggacctcgg ggccgcgcgc
      901 tgcaacgtgg cggcgcccaa cttttacggg ctcgccggga ccatcgagac caacgccccc
      961 gaggtgctcg cgcgcgaccg ctacgacacc aaggtcgacg tctggggcgc gggggtggtg
     1021 ctcttcgaga cgctggccta ccccaagacg atcgccggcg gggacgagcc cgcgatcaac
     1081 ggggagatgc acctgatcga cctcatccgc gccctcgggg tgcaccccga ggagttcccg
     1141 cccgacacgc gcctccggag cgagttcgtc cggtacgccg ggacccaccg ccagccgtac
     1201 acgcagtacg cgcgcgtggc tcgcctcggg ctgcccgaga cgggggcttt cctgatttac
     1261 aagatgttga cgtttgatcc cgtccgccgc ccttccgctg atgagatact caactttgga
     1321 atgtggaccg tataaaacgg cccggctccg agcggtagga cacacacacc tttgcgcatc
     1381 tccacagctc aacaatgaag tgg
//