From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens retinal guanylyl cyclase (retGC) mRNA, complete cds.
Date: 22 Dec 92 22:45:41 GMT
Distribution: bionet
Checksum: 32395 8

LOCUS       HUMRETGC     3503 bp ss-mRNA            PRI       23-NOV-1992
DEFINITION  Homo sapiens retinal guanylyl cyclase (retGC) mRNA, complete cds.
ACCESSION   M92432
KEYWORDS    guanylyl cyclase; photoreceptor specific; retinal protein.
SOURCE      Homo sapiens cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3503)
  AUTHORS   Shyjan,A.W., de Sauvage,F.J., Lu,L., Gillett,N.A., Goeddel,D.V. and
            Lowe,D.G.
  TITLE     The retinal guanylyl cyclase: A photoreceptor specific member of
            the membrane guanylyl cyclase gene family
  JOURNAL   Neuron 9, 727-737 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     82..150
                     /gene="retGC"
                     /codon_start=1
     mat_peptide     151..3387
                     /gene="retGC"
                     /codon_start=1
     CDS             82..3390
                     /gene="retGC"
                     /product="guanylyl cyclase"
                     /codon_start=1
                     /translation="MTACARRAGGLPDPGLCGPAWWAPSLPRLPRALPRLPLLLLLLL
                     LQPPALSAVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLP
                     EPCRTPGSLGAVSSALARVSGLVGPVNPCGLPASRAARRRSRDRAGALGLPLDAGGGH
                     HGPCRDPRRGCPLRPASRIRLGARGPGHRPPGPVGGGGSLTVHGTQGPGLPVASVTSM
                     EPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLGGEEQRYLLEAAEELGLTDGSLVFL
                     PFDTIHYALSPGPEALAHSPTAPSFAGPTMPCSPSRAHCPSEGSVLDSLRRAQERREL
                     PSDLNLQQVSPLFGTIYDAVFLLARGVAEARAAAGGRWVSGAAVARHIRDAQVPGFCG
                     DLGGDEEPPFVLLDTDAAGRPAFCHIHAGSCPGLLLSAGTRMHFPRGGSAPGPDPSCW
                     FDPNNICGGGLEPGLVFLGFLLVVGMGLAGAFLAHYVRHRLLHMQMVSGPNKIILTVD
                     DITFLHPHGGTSRKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFP
                     GDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAASGRATWLWLSEHCTR
                     GSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLDHRGVAHGRLKSRNCIVDGRMVLKI
                     TDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALEHRGTLAGDVFSLAIIMQEVC
                     RSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECIQLMKQCWAEQPELRPSMD
                     HTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQML
                     PPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAI
                     IGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGHFRMRHMPEVPV
                     RIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRAL
                     DSGYQVELRGRTELKGKGAEDTFWLVGRRGFNKPIPKPPDLQPGSSNHGISLQEIPPE
                     RRRKLEKARPGQFS"
BASE COUNT      590 a   1161 c   1117 g    635 t
ORIGIN      
        1 gaattcggcc cacaggggga ccggccctgt gactcctcac cggggccgtg ggcccgagcc
       61 ccggacttcc ctaagccggc aatgaccgcc tgcgcccgcc gagcgggtgg gcttccggac
      121 cccgggctct gcggtcccgc gtggtgggct ccgtccctgc cccgcctccc ccgggccctg
      181 ccccggctcc cgctcctgct gctcctgctt ctgctgcagc cccccgccct ctccgccgtg
      241 ttcacggtgg gggtcctggg cccctgggct tgcgacccca tcttctctcg ggctcgcccg
      301 gacctggccg cccgcctggc cgccgcccgc ctgaaccgcg accccggcct ggcaggcggt
      361 ccccgcttcg aggtagcgct gctgcccgag ccttgccgga cgccgggctc gctgggggcc
      421 gtgtcctccg cgctggcccg cgtgtcgggc ctcgtgggtc cggtgaaccc ctgcggcctg
      481 ccggccagcc gagctgctcg ccgaagaagc cgggatcgcg ctggtgccct ggggctgccc
      541 ctggacgcag gcggagggca ccacggcccc tgccgtgacc cccgccgcgg atgccctcta
      601 cgccctgctt cgcgcattcg gctgggcgcg cgtggccctg gtcaccgccc cccaggacct
      661 gtgggtggag gcgggagcct cactgtccac ggcactcagg gcccggggct gcctgtcgcc
      721 tccgtgactt ccatggagcc cttggacctg tctggagccc gggaggccct gaggaaggtt
      781 cgggacgggc ccagggtcac agcagtgatc atggtgatgc attcggtgct gctgggtggc
      841 gaggagcagc gctacctcct ggaggccgca gaggagctgg gcctgaccga tggctccctg
      901 gtcttcctgc ccttcgacac gatccactac gccttgtccc caggcccgga ggccttggcg
      961 cactcgccaa cagctcccag cttcgcaggg cccacgatgc cgtgctcacc ctcacgcgcc
     1021 cactgtccct ctgaaggcag cgtgctggac agcctgcgca gggctcaaga gcgccgcgag
     1081 ctgccctctg acctcaatct gcagcaggtc tccccactct ttggcaccat ctatgacgcg
     1141 gtcttcttgc tggcaagggg cgtggcagaa gcgcgggctg ccgcaggtgg cagatgggtg
     1201 tccggagcag ctgtggcccg ccacatccgg gatgcgcagg tccctggctt ctgcggggac
     1261 ctaggaggag acgaggagcc cccattcgtg ctgctagaca cggacgcggc ggggagaccg
     1321 gctttttgcc acatacatgc tggatcctgc ccggggctcc ttctctccgc cggtacccgg
     1381 atgcacttcc cgcgtggggg atcagcaccc ggacctgacc cctcgtgctg gttcgatcca
     1441 aacaacatct gcggtggagg actggagccg ggcctcgtct ttcttggctt cctcctggtg
     1501 gttgggatgg ggctggctgg ggccttcctg gcccattatg tgaggcaccg gctacttcac
     1561 atgcaaatgg tctccggccc caacaagatc atcctgaccg tggacgacat cacctttctc
     1621 cacccacatg ggggcacctc tcgaaaggtg gcccagggga gtcgatcaag tctgggtgcc
     1681 cgcagcatgt cagacattcg cagcggcccc agccaacact tggacagccc caacattggt
     1741 gtctatgagg gagacagggt ttggctgaag aaattcccag gggatcagca catagctatc
     1801 cgcccagcaa ccaagacggc cttctccaag ctccaggagc tccggcatga gaacgtggcc
     1861 ctctacctgg ggcttttcct ggctcgggga gcagaaggcc ctgcggcctc tgggagggca
     1921 acctggctgt ggctctcaga gcactgcacg cggggctctc ttcaggacct cctcgctcag
     1981 agagaaataa agctggactg gatgttcaag tcctccctcc tgctggacct tatcaaggga
     2041 ataaggtatc tggaccatcg aggcgtggct catgggcggc tgaagtcacg gaactgcata
     2101 gtggatggca gaatggtact caagatcact gaccacggcc acgggagact gctggaagca
     2161 cagaaggtgc taccggagcc tcccagagcg gaggaccagc tgtggacagc cccggagctg
     2221 cttagggacc cagccctgga gcaccgggga acactggccg gcgacgtctt tagcttggcc
     2281 atcatcatgc aagaagtgtg ccgcagtgcc ccttatgcca tgctggagct cactcccgag
     2341 gaagtggtgc agagggtgcg gagcccccct ccactgtgtc ggcccttggt gtccatggac
     2401 caggcacctg tcgagtgtat ccaactgatg aagcagtgct gggcagagca gccggaactt
     2461 cggccctcca tggaccacac cttcgacctg ttcaagaaca tcaacaaggg ccggaagacg
     2521 aacatcattg actcgatgct tcggatgctg gagcagtact ctagtaacct ggaggatctg
     2581 atccgggagc gcacggagga gctggagctg gaaaagcaga agacagaccg gctgcttaca
     2641 cagatgctgc ctccgtctgt ggctgaggcc ttgaagacgg ggacaccagt ggagcccgag
     2701 tactttgagc aagtgacact gtactttagt gacattgtgg gcttcaccac catctctgcc
     2761 atgagtgagc ccattgaggt tgtggacctg ctcaacgatc tctacacact ctttgatgcc
     2821 atcattggtt cccacgatgt ctacaaggtg gagacaatag gggacgccta tatggtggcc
     2881 tcggggctgc cccaacggaa tgggcagcga cacgcggcag agatcgccaa catgtcactg
     2941 gacatcctca gtgccgtggg ccatttccgc atgcgccata tgcctgaggt tcccgtgcgc
     3001 atccgcatag gcctgcactc gggtccatgc gtggcaggcg tggtgggcct caccatgccg
     3061 cggtactgcc tgtttgggga cacggtcaac accgcctcgc gcatggagtc caccgggctg
     3121 ccttaccgca tccacgtgaa cttgagcact gtggggattc tccgtgctct ggactcgggc
     3181 taccaggtgg agctgcgagg ccgcacggag ctgaagggca agggcgccga ggacactttc
     3241 tggctagtgg gcagacgcgg cttcaacaag cccatcccca aaccgcctga cctgcaaccg
     3301 gggtccagca accacggcat cagcctgcag gagatcccac ccgagcggcg acggaagctg
     3361 gagaaggcgc ggccgggcca gttctcttga gaagtgaggc ccggccccgg acaggattgt
     3421 tctggaaggt ccttttcctg aaagttgctg ctatagggtc tgggccctgc tccctgtccc
     3481 atctgcagtg gaccccaggc acc
//