From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Frog mRNA for tyrosinase, complete cds.
Date: 9 Jan 93 05:47:38 GMT
Distribution: bionet
Checksum: 54704 7

LOCUS       RANTYRS      3511 bp ss-mRNA            VRT       09-JAN-1993
DEFINITION  Frog mRNA for tyrosinase, complete cds.
ACCESSION   D12514
KEYWORDS    tyrosinase.
SOURCE      Rana nigromaculata cDNA to mRNA.
  ORGANISM  Rana nigromaculata
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Amphibia;
            Lissamphibia; Anura; Neobatrachia; Ranoidea; Ranidae.
REFERENCE   1  (bases 1 to 3511)
  AUTHORS   Takase,M., Miura,I., Nakata,A., Takeuchi,T. and Nishioka,M.
  TITLE     Cloning and sequencing of the cDNA encoding tyrosinase of the
            Japanese pond frog Rana nigromaculata
  JOURNAL   Gene 121, 359-363 (1992)
  STANDARD  full automatic
COMMENT     Submitted (01-JUL-1992) to DDBJ by: Atsuo Nakata Research Institute
            for Microbial Diseases Osaka University 3-1 Yamadaoka, Suita Osaka
            565 Japan Phone:  06-875-1606 Fax:    06-875-4327.
FEATURES             Location/Qualifiers
     RBS             43..46
     CDS             55..1653
                     /EC_number="1.14.18.1"
                     /gene="tyrs"
                     /product="tyrosinase"
                     /codon_start=1
                     /translation="MESTTVLLATSTLLLVLHASYGQFPRACSTAQVLLSKECCPVWP
                     GDNSSCGEVSGRGVCQDVVPSNSPVGAQFPFSGIDDRENWPIVFYNRTCQCQGNFMGY
                     NCGECRFGYTGPNCTVRRNMIRKDIFRMTTAEKDKLIAYLNLAKHTISPDYVIATGTY
                     EQMNNGSNPMFADISAYDLFVWIHYYASRDAFLEDGSVWADIDFAHEAPGFLPWHRFY
                     LLLWEREIQKVTGDDNFTIPFWDWRDAQQCELCTDEFFGGTHPTSNNLLSPASFFSSW
                     QIICSRPEEYNSLRIICNGTNEGPLLRSPGRHDRNRTPRLPTSADVEACLSLTDYETG
                     AMDRSANFSFRNTLEGFAVPTSGIANRSQSSMHNSLHVFLNGSMSSVQGSANDPIFVL
                     HHAFVDSLFEQWLRRHQPSLDVYPEANAPVGHNREYNMVPFIPLFTNGEFFVQSRDLG
                     YDYDYLAESGSIEDFLLPYLEQARQIWQWLLGAAVLGGLITAVIATIISLTCRRKRKT
                     KISEETRPLLMEAEDYQATYQSNL"
BASE COUNT      953 a    758 c    770 g   1030 t
ORIGIN      
        1 gggatttttt ttttcccctt ggtttgtttg agaggtctga ggaggatcac taggatggaa
       61 agtactacag tgcttttagc aactagcacc ctgctcctgg tacttcatgc ctcctacgga
      121 cagtttccca gggcttgcag tacagcacag gtcctcttaa gcaaggaatg ttgcccagtc
      181 tggccaggag ataattcttc atgtggagaa gtctccggaa ggggagtgtg ccaagatgta
      241 gtcccctcca actcccctgt gggtgcccag ttccctttct cgggcattga tgaccgagaa
      301 aactggccca ttgttttcta caacaggaca tgccaatgcc agggtaactt tatgggctac
      361 aactgcggtg agtgcaggtt tggctacaca ggaccaaact gcaccgttag acgcaacatg
      421 atcagaaagg acatcttcag gatgaccacg gctgagaagg acaagctcat cgcctatctc
      481 aacttggcca agcataccat cagcccagac tacgttattg ccaccggcac ttacgagcag
      541 atgaacaatg gctccaatcc gatgttcgct gatatcagtg cctatgatct gtttgtgtgg
      601 atacattact atgcctccag agatgctttc ttggaagatg gcagtgtgtg ggccgacata
      661 gactttgccc atgaggctcc gggctttctg ccttggcaca ggttctatct gctgctttgg
      721 gaacgagaaa tccagaaggt gacaggggat gataatttta ctattccctt ttgggactgg
      781 agagatgccc agcaatgtga actctgcact gatgagtttt ttgggggtac gcaccctacc
      841 agcaacaacc tcctcagccc agcttctttc ttctcttcct ggcagattat ttgtagtcgg
      901 cctgaagagt ataacagcct gagaattata tgtaatggta caaatgaagg tcccctactg
      961 cgaagccctg ggcgtcacga caggaaccgg acaccccggt tgcccacttc agccgatgtg
     1021 gaggcctgtt tatccttaac agattatgag accggagcca tggatcgatc tgccaacttc
     1081 agcttcagga acactttaga agggtttgct gttcctactt caggaattgc caacagatca
     1141 caaagcagta tgcacaattc acttcacgtc ttcttgaatg gctccatgtc tagtgttcag
     1201 ggttctgcaa acgaccccat ttttgttctt catcatgcgt ttgttgatag tctctttgaa
     1261 caatggctta gaagacatca gccctcacta gatgtttacc cagaagccaa tgcaccagtt
     1321 ggacacaatc gggaatacaa catggttcca tttattccat tgtttactaa tggagagttc
     1381 tttgtccagt caagagacct ggggtatgat tatgattacc tggcggaatc aggttctatt
     1441 gaagacttcc tgttgcccta tttggagcaa gcaaggcaga tctggcagtg gcttcttgga
     1501 gcggcagtgc ttggagggtt gatcaccgct gtgattgcaa ccatcatcag cttaacgtgc
     1561 cggaggaaac ggaaaacgaa aatctcagag gagacccggc cacttctcat ggaggctgaa
     1621 gactaccagg ccacttacca atccaatcta tgatcatgca tggcagctaa gcagaagttt
     1681 taacatgtac cagggttttt gcttctccac gtgtcagcta atttgaggtc tacaaacaaa
     1741 cctctgggaa attactctac gatcctgcac tgaaagggac atctatgttt gggttacaaa
     1801 atagctgact gcagggttca tgggtaacta aaaaaaaggc tttaatacct tttttatggg
     1861 ttttcattta tctcagtgat aatatatata ttggtacaca tccacagata actatggttg
     1921 tgtaatgctc aacaggcagg aagtgcaggg ggtatcagcc tgaagagaaa accttattgt
     1981 gttgccttta ctaaccacag ttcctttaac agttatctaa aaaattagat tgttgtataa
     2041 gacaaaacct tttcctaatg gaaactataa tgtccatagt gtcctcctag atcgtgtgtt
     2101 gcctctagct ttctaggact ctgtttggca gcttggatgg tttgcattca gatgcttttt
     2161 gatacataag tccataattt ttattggatt ttaggcccca gtatttgtcc cattactaac
     2221 cctttctggt gcagtttcta cttacttttc caataaatag atcggactag tctttgtaag
     2281 aaaaagtttt aaagtaaatc ttccccccaa aaaaatttga gggtttctaa ttatttgcct
     2341 gctatgctgc ttcacttgct tcaatccctg attattcact gcaggtcctt cagcagtctt
     2401 tatctgtata tgtgttcctg aaaataccaa agccaggttt tctgtggaat ggcttaaggc
     2461 taggttcaga gacctttgca tgtacgaaac tgtgcctttc caaacaagct gccattagtg
     2521 gacagtggtg ccattcattt ttaatagtac ctccttgcat ctgcaactgg tagggcgcat
     2581 ttttagaaat gaatcaggga attcacttct gcgtatatca tgaatagggc agcccattaa
     2641 attaaggaaa tgcatgcaag cttgattgca cctgtgggtg tgaaccaatc cataggagga
     2701 gagaacttta atggcagctt ctatgtttaa gtaacagttt tggctggatt tgcaatgttg
     2761 agctgcgttg gtgcatgagc cttatgccat gcattttatt aaggcagtcc attcagttga
     2821 atgagctgcc taacgccaaa agcacaaaac gttgcatgca ctattttttg tgtaatgcag
     2881 tgcacctaaa tgcacatttg tgtgttgatg taccaataca catatctcct tttttttgaa
     2941 gagcaacagt gtgaacccag cttttaatgt ttacctcaaa atgcagtgta ctacattagg
     3001 cagcatattc aaaatgaata ggctgtaaat gcaagagaaa acaggtcctc cacatttttc
     3061 agtacaggtc catgcaattg accgagcata tgtttgtgta caatgcatgt gtgtatgtgt
     3121 attgcagcat tcagatacaa taaacaccac aaccaacttt gcactgcaat gcacatctaa
     3181 attagttcag gtgccacacg ttatgttgtg aatgagccct tggagaaaag caagtaattt
     3241 tgacctgcag ccaaaagtta attttatcta gtgtatcatc aatcatcgat ctgaccagtt
     3301 gctataggca tcaccactat tcctgtgctc cagtatatga agcagaatac ataatatgca
     3361 acagtatgtc cctaaaccat attgtgccat agaatgtaca tgtattgtag cccgtacttt
     3421 tgaaagatat tggtttcata catatagccg gttataaatg gtctgaaatg ggaccaaaaa
     3481 taaaatttta aaaaacttgg gtggaatgga a
//