From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA titin (subclone C37)
Date: 24 Jul 92 10:07:40 GMT
Distribution: bionet
Checksum: 33961    17

LOCUS       HUMTITINC3   9300 bp ss-RNA             PRI       24-JUL-1992
DEFINITION  H.sapiens mRNA titin (subclone C37)
ACCESSION   X64697
KEYWORDS    fibronectin type-III repeat; immunoglobulin-C2; myosin-binding;
            titin gene.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 9300)
  AUTHORS   Labeit,S., Gautel,M., Lakey,A. and Trinick,J.
  TITLE     Towards a molecular understanding of titin
  JOURNAL   EMBO J. 11, 1711-1716 (1992)
  STANDARD  full automatic
COMMENT     *source: clone_library=#936208; *source: isolate=AB5
            immuno-positives; *source: chromosome=2; *source: sub_clone=C37;
            From EMBL    entry HSTITINC3;  dated 12-MAY-1992.
FEATURES             Location/Qualifiers
     CDS             <1..>9300
                     /product="titin"
                     /codon_start=1
                     /translation="PNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSS
                     ENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGY
                     WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASERSRPI
                     MAQNPVDAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVVGYIIERTRVSEVGDGRWLKC
                     NYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD
                     ARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVI
                     KFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQ
                     ENGGAEITHYIVERRETSRLNWVIVEGESATLSYVVTRLIKNNEYIFRVRAVNKYGPG
                     VPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREK
                     ESLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPS
                     YTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATI
                     RNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT
                     VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAG
                     KYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINN
                     YIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAV
                     LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTL
                     KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQ
                     KTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTI
                     RDTGEYTLELKNVTGTTLETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGG
                     APLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQ
                     SEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADR
                     WVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGK
                     PQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYT
                     LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG
                     GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVL
                     ENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILER
                     REVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP
                     LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNKTQ
                     ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILS
                     ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEAT
                     EYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIV
                     GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE
                     TSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSE
                     NITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV
                     IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLT
                     ENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKP
                     PASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLG
                     GESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR
                     QGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV
                     PAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVT
                     RSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDS
                     VNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVI
                     AENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETREVSMTKASHSSTKELYEKYMI
                     AEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILHLH
                     ESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSHNIGH
                     FDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTA
                     TDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDFVDRL
                     LVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARI
                     SCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIENYDQSTQVT
                     WYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK
                     GVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHP
                     EPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS
                     CKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQ
                     PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT"
     repeat_region   1..7344
                     /note="alternating class I and class II repeats"
     misc_feature    7345..8160
                     /note="MLCK-like kinase domain"
     repeat_region   8161..9300
                     /note="class II repeats"
BASE COUNT     2914 a   2000 c   2168 g   2218 t
ORIGIN
        1 cctaattaca tagttgaaaa gcgtgaatcg ggtacaacag cttggcagct tgtcaattcc
       61 agtgtcaagc gcactcaaat taaagtcact catctcacaa aatacatgga atattctttc
      121 cgtgtcagtt cagagaacag atttggtgtc agcaaacctc tagaatcagc accaataatt
      181 gctgaacatc catttgtccc accaagcgct cctaccagac ctgaggtcta ccatgtgtct
      241 gccaatgcca tgtctattcg ttgggaagaa ccctaccacg atggtggcag taaaatcatt
      301 ggctactggg ttgagaagaa agaacgtaat acaattcttt gggtgaaaga aaacaaagtg
      361 ccatgcttag agtgcaacta caaagtaact ggtttagtag aaggactgga atatcagttc
      421 agaacttatg cactcaatgc tgcaggtgtt agcaaggcca gcgaacgttc aagacctata
      481 atggctcaaa atccagttga tgcaccaggc agaccagggg tgacagatgt ccaaagatca
      541 acagtatcac tgatttggtc tgccccagcg tatgatggag gcagcaaggt tgtgggctac
      601 atcatagagc gtacacgagt cagtgaggta ggagatggtc gctggctgaa gtgcaactac
      661 accattgtat ctgacaattt cttcaccgtg actgctctca gtgaaggaga cacttatgag
      721 ttccgtgtgt tagccaagaa tgcagcaggc gtaattagca aagggtctga atctacaggc
      781 cctgtcactt gccgagatga atacgctcca cccaaagccg aactggatgc ccgattacac
      841 ggtgatctgg ttaccatcag agcaggttct gatcttgttc tggatgctgc agttggtggc
      901 aaacctgaac ccaaaattat ctggaccaaa ggagacaagg agctagatct ctgtgaaaaa
      961 gtctctttgc agtatactgg caaacgagca actgctgtga tcaagttctg tgacagaagt
     1021 gacagtggaa aatacacttt aacagtgaaa aatgccagcg ggaccaaggc cgtgtctgtc
     1081 atggtcaaag tgcttgattc ccctggccca tgtggaaagc tcaccgtcag cagagtaaca
     1141 caggagaagt gcactttagc ctggagcctt ccgcaggaga acggaggagc agaaatcact
     1201 cactacatcg tggaaagacg cgagactagc aggctcaact gggtgattgt tgaaggcgaa
     1261 tccgcaaccc tatcctatgt cgttaccagg ctcatcaaga acaatgagta catattccga
     1321 gtgagggcag taaacaaata tggccctggt gtgcctgttg aatcagagcc aattgtagcc
     1381 agaaactcat tcactattcc atcaccaccc ggcatacctg aagaagttgg gactggcaaa
     1441 gagcatatca tcattcagtg gacaaaacct gaatctgatg gtggcaatga aatcagcaac
     1501 tacctagtag acaaacgtga gaaggagagc ctgcgctgga cacgtgtcaa caaagactat
     1561 gtggtgtatg ataccaggct gaaggtgacc agcctgatgg agggttgtga ttaccagttc
     1621 cgggtgaccg cagtgaatgc agctggtaac agtgagccca gcgaacgttc caacttcatc
     1681 tcatgcagag aaccatcata tacccctgga ccaccttctg ctccaagagt tgtggatacc
     1741 accaaacaca gcattagttt ggcatggacc aaacccatgt acgatggtgg tactgacatt
     1801 gtaggatatg ttctggaaat gcaagagaag gacactgatc agtggtaccg agtgcatacc
     1861 aatgccacaa taagaaatac tgaattcact gtgccagacc ttaaaatggg ccagaaatat
     1921 tccttcagag ttgctgccgt gaacgtgaag ggtatgagcg aatacagcga atcaattgct
     1981 gaaattgagc ccgtggaaag aatagaaata ccagatcttg agcttgcaga tgatctaaag
     2041 aagactgtga ccatcagggc tggggcctcc ttgcgcttga tggtgtctgt atctggaaga
     2101 ccacctcctg tcataacgtg gagcaagcag ggcattgacc ttgcaagccg ggcaattatt
     2161 gacaccactg agagctactc attgctaata gtggacaaag ttaatcggta cgatgctgga
     2221 aaatacacaa ttgaagctga aaaccaatct ggcaagaaat cagcaacagt ccttgttaaa
     2281 gtctatgata ctcctggtcc ctgtccttca gtgaaagtta aggaagtatc aagagattct
     2341 gtgactataa cttgggaaat tcccacgatt gatggtggag ctccaatcaa caattacatc
     2401 gttgagaagc gtgaagctgc tatgagagca ttcaaaacag taactaccaa atgcagcaag
     2461 acactttaca gaatttctgg acttgtagaa ggaaccatgc actatttcag agtgctgcca
     2521 gaaaatattt atggcattgg agaaccttgt gaaacatctg atgcagtact ggtctcagaa
     2581 gtgcctttgg tgcctgcaaa gctagaagtg gtcgatgtca ccaaatccac tgttaccctt
     2641 gcctgggaaa aaccactcta cgatggtggt agccgactca ctggatatgt tctcgaggcc
     2701 tgcaaagctg gcacagagag atggatgaag gttgtcacct taaaacccac agtcctagag
     2761 cacactgtta cttccttaaa tgaaggtgaa caatacttat ttagaataag ggcacaaaat
     2821 gagaaaggtg tgtcagaacc aagagagact gtcacagccg tgactgtaca agacctcaga
     2881 gtgttgccaa caatcgatct ttctacaatg cctcagaaga ccatccatgt cccagctggc
     2941 agaccagtag agctggtgat acctattgct ggccgtccac ctcctgctgc ttcctggttc
     3001 tttgctggtt ctaaactgag agaatcagag cgtgtcacag ttgaaactca cactaaagta
     3061 gctaaattaa ccatccgtga aaccactatc agagatactg gagaatacac acttgaattg
     3121 aagaatgtta ccggaactac tttagaaacc attaaagtta tcattcttga caagcctggt
     3181 ccaccaacag gacctattaa gattgatgaa attgatgcta catcaattac catttcctgg
     3241 gaaccacctg aattggacgg tggtgctcca ctgagtggtt atgtggtaga acaacgtgac
     3301 gctcatcgtc caggatggct gcccgtttct gaatcagtga ctaggtccac gtttaagttt
     3361 accagactca ccgaaggaaa tgagtatgtg ttccgtgtgg ctgcaacaaa ccgcttcggg
     3421 attggctctt acttgcagtc tgaggtcata gagtgtcgca gcagcatccg tattcctgga
     3481 cccccagaaa cattacagat atttgatgtt tcccgtgatg gcatgacact tacttggtac
     3541 ccaccagagg atgacggtgg ctcccaagtg actggatata ttgtggagcg caaagaagtg
     3601 agagcagatc gatgggtccg tgtaaataaa gtacctgtga caatgacacg gtaccgctcc
     3661 actggcctta ctgaaggctt agaatatgaa caccgtgtca cagccattaa tgcaagaggg
     3721 tctgggaaac caagtcgtcc ttccaaaccc atcgttgcca tggatccaat tgctcctcca
     3781 ggaaagccac aaaacccaag agttactgat acaacaagga catcagtctc cctggcctgg
     3841 agtgttccag aagatgaagg aggatctaaa gtcacaggct acttgattga aatgcaaaaa
     3901 gtagatcaac atgaatggac caagtgtaac accactccaa ccaagattcg agagtatact
     3961 ctaacacacc tacctcaggg tgcagaatac aggttccgcg tcctagcttg taatgctggt
     4021 ggacctggtg agcctgctga ggtaccagga acagtcaaag tcactgaaat gcttgaatat
     4081 cctgattatg aacttgatga aagataccaa gaaggtatct ttgtaaggca aggtggcgtc
     4141 atcagactta ccataccaat caaagggaaa ccattcccaa tatgtaaatg gaccaaggaa
     4201 ggccaggata ttagtaagcg tgccatgatt gcaacatctg aaacacacac tgagcttgtg
     4261 atcaaagaag cagacagggg tgattctggc acttatgacc tggttctgga aaataaatgt
     4321 ggcaagaagg ctgtctacat caaggtcagg gtgataggaa gtcccaacag tccagaaggg
     4381 ccactggaat atgatgacat ccaagtccgc tctgtgaggg tcagctggag acctcctgct
     4441 gatgatggtg gtgctgacat cttaggctac atcctcgaga gacgagaagt gcctaaagcc
     4501 gcctggtata ccattgattc cagagtccga ggtacatctc tggtggtaaa aggcctcaaa
     4561 gagaatgtag aataccattt ccgtgtttca gcagaaaacc agtttggcat aagcaaaccc
     4621 ttgaaatctg aggaaccagt cacaccaaaa acaccattga atcctccaga acctccaagc
     4681 aatcctccag aagtactcga tgtaaccaag agttctgtta gcttgtcctg gtcccggccc
     4741 aaagatgatg gtggttctag agtcacaggc tactacatcg aacgcaaaga gacatccact
     4801 gacaaggtgg tcagacacaa caagactcag atcaccacca caatgtacac tgtcacaggg
     4861 cttgttcccg atgctgagta tcagttccgc atcatcgcac agaatgatgt tggcctgagt
     4921 gagaccagcc ctgcttctga accagttgtt tgcaaagatc catttgataa accaagccaa
     4981 ccaggagaac ttgagattct ttcaatatcc aaagatagtg tcactctaca gtgggagaaa
     5041 cctgaatgtg atggtggtaa agaaattctt ggatactggg ttgaatatag acagtctgga
     5101 gacagtgcct ggaagaagag caataaggaa cgtattaagg acaagcaatt cacaatagga
     5161 ggtttgctgg aagctactga gtatgaattc agggtttttg ctgagaatga gactgggctg
     5221 agcagacctc gcagaactgc tatgtctata aagactaaac tcacatctgg agaggcccca
     5281 ggaatacgca aagaaatgaa ggatgttacc acaaaattgg gtgaagctgc tcaactctca
     5341 tgccagattg ttggaaggcc tcttcctgac attaaatggt acagatttgg taaagagctc
     5401 atacaaagcc ggaaatacaa aatgtcttca gatggacgca cacacactct tacagtaatg
     5461 acagaggaac aggaagatga aggtgtttat acctgcatag ccaccaatga ggttggagaa
     5521 gtagaaacca gtagtaagct tctcctgcaa gcaacaccgc agttccatcc tggttaccca
     5581 ctgaaagaga aatattatgg agctgtgggt tccacacttc ggcttcatgt tatgtacatt
     5641 ggtcgtccag tacctgccat gacttggttc catggtcaga aacttttgca aaactcagaa
     5701 aacattacta ttgaaaacac tgagcactat actcatcttg tcatgaagaa tgtccaacgt
     5761 aagactcatg ctgggaaata caaagtccag ctcagcaatg tttttggaac agttgatgcc
     5821 atccttgatg tggaaataca agataaacca gacaaaccta caggaccaat tgtgatcgaa
     5881 gctctattga agaactccgc agtgatcagc tggaaaccac ccgcagatga cggaggctcc
     5941 tggatcacca actatgtggt ggaaaaatgt gaggccaagg agggggctga atggcaattg
     6001 gtgtcttcag ccatctcagt gacaacctgt agaattgtga acctcacaga aaatgctggc
     6061 tattacttcc gggtttcagc tcagaacact ttcggcatca gtgaccctct agaagtgtcc
     6121 tcagttgtga tcattaagag tccatttgaa aagccaggtg ctcctggcaa accaactatt
     6181 actgctgtca caaaagattc ttgtgttgtg gcctggaagc cacctgccag tgatggaggt
     6241 gcaaagatta gaaattacta ccttgagaag cgtgagaaga agcagaataa atggatttct
     6301 gtgacaacag aagaaattcg agaaactgtc ttttcagtga aaaaccttat tgaaggtctt
     6361 gaatacgagt ttcgtgtgaa atgtgaaaat ctaggtgggg aaagtgaatg gagtgaaata
     6421 tcagaaccca tcactcccaa atctgatgtc ccaattcagg caccacactt taaagaggaa
     6481 ctgagaaatc taaatgtcag atatcagagc aatgctacct tggtctgcaa agtgactggt
     6541 catccaaaac ctatcgtcaa atggtacaga caaggcaaag aaatcattgc agatggatta
     6601 aaatatagga ttcaagaatt taagggtggc taccaccagc tcatcattgc aagtgtcaca
     6661 gatgatgatg ccacagttta ccaagtcaga gctaccaacc aagggggatc tgtgtctggc
     6721 actgcctcct tggaagtgga agttccagct aagatacact tacctaaaac tcttgaaggc
     6781 atgggagcag ttcatgctct ccgaggtgaa gtggtcagca tcaagattcc tttcagtggc
     6841 aaaccagatc ctgtgatcac ctggcagaaa ggacaagatc tcattgacaa taatggccac
     6901 taccaagtta ttgtcacaag atccttcaca tcacttgttt tccccaatgg ggtagagaga
     6961 aaagatgctg gtttctatgt ggtctgtgct aaaaacagat ttggaattga tcagaagaca
     7021 gttgaactgg atgtggctga tgttcctgac ccacccagag gagtcaaagt tagtgatgcc
     7081 tcacgagatt ctgtcaactt aacatggact gagccagcct ctgatggtgg cagcaaaatc
     7141 accaactaca ttgttgaaaa atgtgcaact actgcagaaa gatggctccg tgtaggacag
     7201 gcccgagaaa cacgttatac cgtgatcaac ttatttggaa aaacaagtta ccagttccgg
     7261 gtaatagctg aaaataaatt tggtctgagc aagccttcag agccttcaga accaaccata
     7321 accaaagaag ataagaccag agctatgaac tatgatgaag aggtagatga aaccagggaa
     7381 gtctccatga ctaaagcatc tcactcttca accaaggaac tctatgagaa atatatgatt
     7441 gctgaagatc ttgggcgtgg tgagtttgga attgtccatc gttgtgttga aacatcctca
     7501 aagaagacat acatggccaa atttgttaaa gtcaaaggga ctgatcaggt tttggtaaag
     7561 aaggaaattt ccattctgaa tattgctagg catagaaaca tcttacacct ccatgaatca
     7621 tttgaaagca tggaagaatt agttatgatc tttgagttta tatcaggact tgacatattt
     7681 gagcgcatta acacaagtgc ttttgaactt aatgaaagag aaattgtaag ttatgttcac
     7741 caggtctgtg aagcacttca gtttttacac agtcataata ttggacactt tgacattaga
     7801 ccagaaaata tcatttacca aaccagaaga agctctacca ttaaaatcat agaatttggt
     7861 caagcccgtc agctgaaacc aggggacaac ttcaggcttc tattcactgc cccagaatac
     7921 tatgcacctg aagtccacca gcatgatgtt gtcagcacag ccacagacat gtggtcactt
     7981 ggaacactgg tatatgtgct attgagtggt atcaacccat tcctggctga aactaaccaa
     8041 cagatcattg agaatatcat gaatgctgaa tatactttcg atgaggaagc attcaaagag
     8101 attagcattg aagccatgga ttttgttgac cggttgttag tgaaagagag gaaatctcgc
     8161 atgacagcat cggaggctct ccagcaccca tggttgaagc agaagataga aagagtcagt
     8221 actaaagtta tcagaacatt aaaacaccgg cgttattacc acaccctgat caagaaagac
     8281 ctcaacatgg ttgtgtcagc agcccggatc tcctgtggtg gtgcaattcg atctcagaag
     8341 ggagtgagtg ttgctaaagt taaagtggca tccattgaaa ttggcccagt ttctgggcag
     8401 ataatgcatg cagttggtga agaaggagga catgtcaaat atgtatgcaa aattgaaaat
     8461 tatgatcagt ctacccaagt gacttggtac tttggtgtcc gacagctgga gaacagtgag
     8521 aaatacgaaa tcacctacga agatggagtg gccatcctct atgtcaaaga cattaccaaa
     8581 ttagatgatg gtacctacag atgcaaagta gtcaatgact atggtgaaga cagttcttat
     8641 gcagagctat ttgttaaagg tgtgagagaa gtctatgact attactgccg tagaaccatg
     8701 aagaaaatta agcgcagaac agacacaatg agactcctgg aaaggccacc agaatttacc
     8761 ctgcctctct ataataagac agcttatgta ggtgaaaatg tccggtttgg agtaactata
     8821 actgtccacc cagagcctca tgtaacatgg tataaatcag gtcagaaaat caaaccaggt
     8881 gacaatgaca agaagtacac atttgagtca gacaagggtc tttaccaatt aacaatcaac
     8941 agtgtcacta cagatgatga cgctgaatat actgttgtgg caaggaacaa atatggtgaa
     9001 gacagctgta aagcaaagct gacagtaacc ctacacccac ctccaacaga tagtacctta
     9061 agacccatgt tcaaaaggtt actggcaaat gcagaatgcc aagaaggcca aagtgtctgc
     9121 tttgagatca gagtgtctgg catcccccca ccaacattaa aatgggagaa agatggtcag
     9181 ccactgtccc tcgggcctaa cattgaaatt atccatgaag gcttggatta ttatgctctg
     9241 cacatcaggg acactttgcc tgaagacacg ggttattata gagtcacagc cactaacaca
//