From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens erythropoietin gene 5' flank including Alu repeats.
Date: 5 Jan 93 06:46:42 GMT
Distribution: bionet
Checksum: 00026 10

LOCUS       HUMERPALU    5169 bp ds-DNA             PRI       04-JAN-1993
DEFINITION  Homo sapiens erythropoietin gene 5' flank including Alu repeats.
ACCESSION   M97764
KEYWORDS    Alu repeat; erythropoietin.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Lin,F.-K., Suggs,S., Lin,C.-H., Browne,J.K., Smalling,R.,
            Egrie,J.C., Chen,K.K., Fox,G.M., Martin,F., Stabinsky,Z.,
            Badrawi,S.M., Lai,P.-H. and Goldwasser,E.
  TITLE     Cloning and expression of the human erythropoietin gene
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 82, 7580-7584 (1985)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 5169)
  AUTHORS   Blanchard,K.L., Acquaviva,A.M., Galson,D.L. and Bunn,H.F.
  TITLE     Hypoxic induction of the human erythropoietin gene: Cooperation
            between the promoter and enhancer, each containing steroid receptor
            response elements
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     repeat_region   one-of(3532..3555,3555..3578)
                     /rpt_type=direct
     repeat_region   one-of(4678..4697,4989..5008)
                     /note="'direct repeat flanking Alu5'"
     repeat_region   complement(one-of(4019..4030,4334..4345))
                     /note="'direct repeat flanking Alu4'"
     repeat_region   complement(one-of(2315..2330,2650..2665))
                     /note="'direct repeat flanking Alu3'"
     repeat_region   complement(one-of(1819..1830,2162..2173))
                     /note="'direct repeat flanking Alu2'"
     repeat_region   one-of(5164..5169,1240..1256)
                     /note="'direct repeat flanking Alu1'"
     repeat_region   949..1239
                     /rpt_family="'Alu'"
                     /label=Alu1
                     /partial
                     /note="Alu homology from bp 953-1252"
     repeat_region   complement(1831..2161)
                     /rpt_family="'Alu'"
                     /label=Alu2
                     /partial
                     /note="Alu homology from bp 1854-2153"
     repeat_region   complement(2331..2649)
                     /rpt_family="'Alu'"
                     /label=Alu3
                     /note="Alu homology from bp 2346-2654"
     repeat_region   complement(4031..4333)
                     /rpt_family="'Alu'"
                     /label=Alu4
                     /note="Alu homology from bp 4029-4328"
     repeat_region   4698..4988
                     /rpt_family="'Alu'"
                     /label=Alu5
                     /note="Alu homology from bp 4704-5003"
     misc_feature    5164..5169
                     /citation=[1]
                     /note="Overlap with positions 1-6 in GenBank entry M11319"
BASE COUNT     1224 a   1339 c   1300 g   1305 t      1 others
ORIGIN      
        1 ggatcccagg gagctgggtt gaccggggga tggctcagtg ccccctctag gttgggttct
       61 tctctgagca tgtagtggag ggaccacata atgcaatcca cacttgggtg gttaccacag
      121 aaaagggaca tgctggacgc ttggtagaca gaaaaatgca tcagaacttc catacgtcag
      181 cccttcgctc tcttcgatga ctagggcacc tgcactacgt gactccagac ggtaccattc
      241 ccttcagagt ctctatggat gcccctggga gttgggcagt gctcagcttt gacggctgtc
      301 catggcggtc ctgccagtga gatgcctaag acatgtacat aaatgacggc agtgccaggg
      361 aaggagacga tttcctgctg ggagatcaag aaaggcttca tggaggaggc gatgcacaga
      421 tttgggcttt aaagaaaacg aggagatggt gtgggagggt aatccaggat gagccaaggg
      481 caggaaggca caaaccatct cctgtggtgg agggagtggg agtgagcaaa gcggngagaa
      541 cagcctggaa catgaagtga atggtagacc ttggagggtc tcagttctga ggcaatagga
      601 agccgtggca ggttcctgct cagggaatta gcacaaatga ggctgttcag tgggaaagtt
      661 aattgagcag cagggttagg gattaactgg aggggtcaat gaggagatgc tctgcagtgg
      721 tcctgggcct gtgggtcagc atctgctaga agatgaagag caggcagatg acgggggtgg
      781 ggggcactgg gcagggggat ggtgggcatt ggtcggggag ccccatggag cttcttgttt
      841 tcttcctgtt cctcaaggac agatgaatgg accctgcatt gctcagtatc caagaggctc
      901 tgggctccaa accagcctct cccctcttag cagaattact atggcttcaa gccggttgtg
      961 gtggctcacg cctgtaatcc cagcactttg ggaggccgag gcgggcggat cacttgaggt
     1021 tgggagttcg agaccagcct ggccaacatg gcgaaacccc atctctactg aaaatacaaa
     1081 aattaccggg cgtggtggca catgcctgta attccagcta ctcgggaggc tgaggcagga
     1141 gaattgcttg aacccgggag gtggaggttg cagtgagctg agataatggc accactgcac
     1201 tccagcctgg gcaatagagt gagactccat ctcaaaaaga gaattactat ggcttcggat
     1261 tgggtatggg gtggaccaag atcctctcct ccctcccaag ctgcaatcac agctctctct
     1321 ccagaagccc caggggacaa ggcagtcact actcctatcc agcaggctac agcatttaga
     1381 ggctggtgcc cctggcccat ctctcactcc tcttcaactg cagacaagga tgcagggacc
     1441 cccgagaagc tgtgtgaggg gaggggcagg tcccacagcc caaaaggctc ctcctcctcc
     1501 agctgtgtcc accccaccca tctgtctccg gccccctctc catggttagg tcagggcatt
     1561 gacgcaggag tcagggtcct gggagagcag aggctgggga aggggagcag ccaagacaga
     1621 acgcacgtgc ggccatgtgt ggatgtgagt gtgatggtgc acgtcccagg actctggaag
     1681 ggatcagaac caggagccga gtggggctgg gggagctgga cagcagtttt gggaaggctc
     1741 aaggtgagca gaggatgcag gggagcaggg tctgagggaa ttaggccagc cagaagcata
     1801 ccagcctctg tctcctgacc cccacccaac catcttgcca aaccactcat tttttctttt
     1861 ttttttttga gacagggtct ccctttgttg cccagtctag agtgcagtgg cgtgatcata
     1921 gctcactgca gcctcaacct cccgggctca agagatcctc tgacctcagc ctcctgagta
     1981 gctgggacta cagatgtgca ccaccatgcc cagctagcta aacaaaaata aaaattatag
     2041 actatgggat ctcactatgt tgcccaggct ggtctcaaac tcctggcctc aagcaatcct
     2101 cctgcctcag cctcccaaaa tgttgggatt acaggtgtga gccactacac ttggcccaaa
     2161 tccccctccc atcaagctct tcacctcacc acaccctcat ggtccctcac ccccaacagg
     2221 tctttattca agtcagtttc tcagcctagt gtctctgact accttatttt agataaccct
     2281 gcctgtgcct tttctcctta gttctggcta tttgaaatcc tctatctttt cttttctttt
     2341 ctttcttttt tttttttttt tttgagacag ggtctcattc tgttgcccag ggtggagtgc
     2401 agtagcaaaa ccacagctca ctgcagcctc aacttcctgg gctcaagtga tcctcccacc
     2461 tcagcctccc aagtagctgg gactataggc acatgccatc atgcccagct aatttttgta
     2521 tttttttgta aagatggggt ttcaccatgt tgcccaggct ggtcaagcca actccagggc
     2581 tcaagtgatc ctcttgcctt ggcctcccga agtgctggga ttacaggcat gagccacctc
     2641 acccagccaa aatcctctgt cttgtaccca tttttgtgtt catcattggc aaccccacta
     2701 gaacgtcagc tccaccaggg caggcattcc tggctgtatc attcactgct ctatccccag
     2761 gtccttggcc aggggtaggt aggaaatcca taaatatctt ttgaatgaat gagtgaatgt
     2821 ttcccactct ttccaaacaa aatccaaatt cttcagagag gcattcaagg ccatagacag
     2881 cctgactcct ccctaagcag caccctggcc tcatcttcca cctctctctt ctccatcttc
     2941 ccttctgctc acctgtaggg agaccccctg aaactactgc tacggaataa aagatgaaat
     3001 gctcctgatt attgtaaata caaaattgca tgcaggattg tgtacaaaca atgccaggtt
     3061 ggactgccag aatgagccaa cagcctgtga tgtgcttccg cctgcggaga gcctatgaac
     3121 ggacctgcag tcagggaggt ttcacatcac caagatttct atcccagaaa agcagatgtt
     3181 catagctctg ggaatggaat gcgacccttg tggagagcct ataaacggac gcatggcggg
     3241 ggggcacctg tccatatgga taagataggg ctataaacgc cctcatcttg ccatggctct
     3301 tctaggcctc tttagggtta aggcatactc ccttctgaga atttctggtc taactggttg
     3361 tctagcttca tgtcctgttt ccatggattg tctgtaacca gcttttgttg caattgttac
     3421 tgctgattag tatcttgcta atcataggtt atggaaagat tgtgtttctg ttttaaggct
     3481 ctgttagaaa ttactgatgc acacactata ttgtaaattc ttatctctgt atactgtact
     3541 tctgcataca aaggtactgt acttctacat ataaatgtta tgttaaagaa ttaattcatc
     3601 cccatgtgac catctcacct cataatcaaa tgaccctaaa tccctcacta acctaccccc
     3661 gccctcacta aacttaataa taaatgatgg tacatctggt gcattgttga caccacggga
     3721 ccagaaggcg gtgacccccc tggaccagct ttcactatct tgtgtgtgtc tattatttct
     3781 caacctgctg atccgcctgg gaacaaagag agagccctgt tgcattgcgg gctgctggcc
     3841 agatcccgca atactcacct gactctccat tcactttgct gaatcgacaa tcccccaccc
     3901 acctcatacc tcttcccatt gatgtcctac cccccttcaa ggctgaggtc attgtcacct
     3961 cctccctcaa atctttcttg atttctcccg gctaactctt acagctcaga tctacacatt
     4021 ccagtctttt tttgtttttg agacaggctc tcactctgac gcccaggctg cagtgcagtg
     4081 gcacgatcat ggctcactac ggcctcgaac tcctgggctc aggtgatcct cctgccttag
     4141 cctcctgcat atttgggact ataggcgtga gccaccacac ctgactaatt attttttatt
     4201 tatttattta ttttagagac aaggtcttgc catgttgtcc gggctggtct cgaactcctg
     4261 ggctcaaagg atcttcctgc cttggtctcc caaagtgctg ggattatagg tgtcagctgc
     4321 ggcgcctgga cctttcctgt cttttatgaa acctgaatgg gataggctgg tagtttcacc
     4381 acacccattt gacagatgag gacattgagg gctcaaggac gaggccactt tctaaggtgt
     4441 gagagaccag ctagtcttgg tctcctgctc tgggaatctc actcatctgg ctcagggttt
     4501 ccagaagcca taaaacctta gctgtaaatc ccagccccca tcactcttgg tgttagctgt
     4561 atttcagtgt tcttaagaac tcagcaatgc agcctagcta acctacacca caggtcaaat
     4621 aaacagatgt caaggtgcat gtgtgtcctg cacaatggac tgtgtgctct gtgcactaaa
     4681 agttaagtgt ctggggtggg ggctgggtgc ggtggctcac gcctgcaatc ccagcacttt
     4741 gagaggccga ggagggtgga tcacctgagg tcaggagttc aagaccggta tggcaatatg
     4801 caacacccca tctctactaa aaatacagaa catagccggg tgtaaaggtg tgcctgtagt
     4861 cccagctgct ccagaggctg aagcaggaga attgcttgaa cccaggaggc agaggttgta
     4921 gtgaacggga gatggcacca ctgcactgcc tgggcaacat agggaggcta catctccaga
     4981 aaaaaaaaaa aagttaagtg tctgggtttg cagagtacta gagggtgagg agtgaggtgg
     5041 ggaggaagaa ccccaaattt cttgccctat ttgcccccat caaattcctc aacatggtca
     5101 acattgtttc tagaacatgt cctgggattg tgggaaggga gaccactcat ttgcccctcc
     5161 ctaaagctt
//