From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Xenopus laevis DNA for IgM VH-II region
Date: 22 Dec 92 22:47:43 GMT
Distribution: bionet
Checksum: 03415 4

LOCUS       XELIMVHII     620 bp ds-DNA             VRT       23-NOV-1992
DEFINITION  Xenopus laevis DNA for IgM VH-II region
ACCESSION   X14922 M37534 X12551
KEYWORDS    constant region.
SOURCE      Xenopus laevis DNA.
  ORGANISM  Xenopus laevis
            Eukaryota; Animalia; Chordata; Vertebrata; Amphibia; Lissamphibia;
            Anura; Archeobatrachia; Pipoidea; Pipidae; Xenopodinae.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Schwager,J., Grossberger,D. and Du Pasquier,L.
  TITLE     Organisation and rearrangement of immunoglobulin M genes in the
            amphibian Xenopus
  JOURNAL   EMBO J. 7, 2409-2415 (1988)
  STANDARD  full automatic
COMMENT     *source: tissue=blood; cell type=erythrocyte; library=lambda EMBL3;

               From EMBL 27   entry XLIMVHII;  dated 30-JAN-1990.
FEATURES             Location/Qualifiers
     mRNA            <144..144
     promoter        19..26
                     /note="CAAT-box"
     promoter        46..50
                     /note="TATA-box"
     intron          145..240
                     /note="Intron I"
     mRNA            241..540
     intron          541..>620
                     /note="Intron II"
     precursor_RNA   620..>620
                     /note="primary transcript"
     CDS             100..141
                     /note="(AA -19 to -4)"
                     /partial
                     /note="pre-IgM VH-II region"
                     /codon_start=1
                     /translation="MESVILLVLLVFAP"
     CDS             100..141
                     /note="(AA -19 to -4)"
                     /partial
                     /note="signal peptide"
                     /codon_start=1
                     /translation="MESVILLVLLVFAP"
     CDS             241..537
                     /note="(AA -3 to 97)"
                     /partial
                     /note="pre-Igm VH-II region"
                     /codon_start=1
                     /translation="ILSQTLQESGPGTVKPSESLRLTCTVSGFELSSYKMHWVRQPPG
                     KGLEWIVVIATGGSTAIADSLKNRVTITKDNGKKQVYLQMTGMEVKDTAMYYCAR"
     CDS             241..246
                     /note="(AA -3 to -1)"
                     /partial
                     /note="signal peptide"
                     /codon_start=1
                     /translation="IL"
     CDS             250..537
                     /note="(AA 1 - 97)"
                     /partial
                     /note="IgM VH-II region"
                     /codon_start=1
                     /translation="QTLQESGPGTVKPSESLRLTCTVSGFELSSYKMHWVRQPPGKGL
                     EWIVVIATGGSTAIADSLKNRVTITKDNGKKQVYLQMTGMEVKDTAMYYCAR"
BASE COUNT      204 a    108 c    132 g    176 t
ORIGIN      
        1 atatttggca gatcccctat gcaaatacta actttttttc agcactataa agaggatatg
       61 tatccttcgt aaagcacttt atccaaattt tttgctaaca tggaaagtgt tattctttta
      121 gttttgctgg tgtttgcccc attatgtaag gaatttgtga catattttag ctgtttaata
      181 tgaatgaaga aaatgaagaa aatgaaatat ttcatgctaa tctcactctt atttgcaggt
      241 atcctctctc agacattaca agagtctggt cctggaactg tgaaaccctc agagtcactc
      301 agactaacct gcacagtttc tgggtttgag ctaagtagct ataagatgca ctgggtcagg
      361 cagcctcctg ggaagggact ggaatggatt gtagttatag cgactggtgg gagcacagct
      421 attgctgatt cacttaaaaa cagagttaca attactaaag acaatgggaa gaagcaggtc
      481 tacctccaaa tgactgggat ggaagttaaa gacactgcca tgtattactg tgcaagagag
      541 acacagtgac agaaaaaatt aggaagtcag acaatatcac aatgtaggat tgcagtgcac
      601 agaaacaagc aacaaaatga
//