From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus myogenic regulatory factor (MyoD) gene, complete
Date: 19 Aug 92 10:03:44 GMT
Distribution: bionet
Checksum: 41070    11

LOCUS       RATMYOD      6490 bp ds-DNA             ROD       19-AUG-1992
DEFINITION  Rattus norvegicus myogenic regulatory factor (MyoD) gene, complete
            cds.
ACCESSION   M84176
KEYWORDS    myogenic regulatory factor; transcription factor.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda Charon
            4A) female adult liver DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 6490)
  AUTHORS   Vaidya,T.B., Rhodes,S.J., Moore,J.L., Sherman,D.A., Konieczny,S.F.
            and Taparowsky,E.J.
  TITLE     Isolation and structural analysis of the rat MyoD gene
  JOURNAL   Gene 116, 223-230 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             join(2591..3217,3667..3745,4060..4310)
                     /product="myogenic regulatory factor"
                     /gene="MyoD"
                     /codon_start=1
                     /translation="MELLSPPLRDTDLLGPDGSLCSFATRDDFYDDPCFDSPDLRFFE
                     DLDPRLVHVGALLKPEEHAHFPTTVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACK
                     RKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGL
                     QALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSG
                     PRRQNGYDAAYYSEASSEPRPGKSAAVSSLDCLSSIVERISTDSPAAPSLLLPDAPPE
                     SPPGPPEETSSSDAEQGTQTPSPDSTPQCPAGSKPNPIYQVL"
     mRNA            join(2381..3217,3667..3745,4060..5090)
                     /gene="MyoD"
     TATA_signal     2356..2361
                     /gene="MyoD"
     exon            2381..3217
                     /number=1
                     /gene="MyoD"
     intron          3218..3666
                     /number=1
                     /gene="MyoD"
     exon            3667..3745
                     /number=2
                     /gene="MyoD"
     intron          3746..4059
                     /number=2
                     /gene="MyoD"
     exon            4060..5090
                     /number=3
                     /gene="MyoD"
     polyA_signal    5053..5058
                     /gene="MyoD"
BASE COUNT     1526 a   1811 c   1659 g   1494 t
ORIGIN
        1 gaattcagct acttttcacc agattcactt tgcctcccaa aagtaagcag ccgcctgagt
       61 ggccatgagc actcgttcag actgtggcag tgtcctctga ctgggccacc ttttatgtcc
      121 tcacctccca cctacttgta gagcactgag ccgagacccg attcagccaa tcccagggaa
      181 agaccaggga acagaactaa agttgagagt agcgagaata actctgagga tggatccctg
      241 ttcagtatta gaggaaaggg gtgggggagg aagaggagga cgagaaagaa ggggaagagg
      301 aggagaactg gaagaataaa actagaacag agccattaag aagaatggtg gctcccagtc
      361 aagttgggga cacaagctga gttcgagcct gcttgctatg cattaaacct atcgagcagt
      421 gctgccccag gacctttaca catgtttgtc cctctctcta accctaaata tctgctaata
      481 gtagcttctg tctcccttca tccagggcac tacacaaaca cagctatccc agaggatcct
      541 tccctgatcg ctggaataaa gattacttct tgctttattt taatttttat tttattttgt
      601 ggagttggta aacccctgat accacaaaca cccttgcttg attgacttcc ctataattca
      661 actacgtgaa taggaccttg gttgtgttta ctgctgggtc ccccataccc cgaccagtag
      721 ctattgtgtg ctagataagc cacagtgaat gctggatgaa caaacaaagg cgaaaccatg
      781 gggtaagtgt gagcacttca tgatggagac catcagcccc cctggtgtcg gagacatgaa
      841 aacctttgga ctccaaaaga ggttcctggc ttggtctgct gggtagagag ggctttccag
      901 tctgtacgat gggccagtta agatgacttc cagaagtttg tgggaaagac acctacataa
      961 cccttgctta ggtttctggc atccaggaga gaagacatag ccaaggaaga cttctagcca
     1021 gaaccctcaa aagcatgagc atcccagggt tggggtgtgt tgggttgtgt aggagagaca
     1081 gagatcccac aaggtgcccc ttccttttga tcctacctcc ccagtgaacc tgctggaaga
     1141 gactcagcta cagtctccag agaaacagag ccagagcctc caggggcctc tgccagggct
     1201 cagtgtccca ggcagtctga gaagcttgct ggttatacta tgcaactggg tgctggagac
     1261 agaagcaaga agatggcaga gtcatgcacc tccactgaca tttccacatc cttccctgat
     1321 ttggattctc aatcatcacc acagttactc ctggacattg tcattgttcc tgggtatgta
     1381 gtggacacgg acttgggaag agcgtcatct caacaaaatt gtgtggactc tactgtaggt
     1441 gagatcctca gccaagtcct ggccatcacg acccttaaga aaggcatttc ccattgctcc
     1501 cctcggagca aaaacggttt tcttcttctc tgtagaaaca gatcaaccta gacacccccc
     1561 ccgcatcccc ctccccacct tgggtctcta gacacttcca gaaggaatcc tgttcacaga
     1621 acagacccat aagttgggta gagcctccct ctccctccct cttttccttg ggctgtccac
     1681 cccagtttga atagaatggc ttgaagtttt gatgatgatt cccactacac atagataagc
     1741 cgggattcta agcttcctgt gaaagatcag atgttctctg agccattccc aggtggagaa
     1801 tgaccagata acactgtcag taaatcattt ttgtctccgg tttgcccacc tagacatttt
     1861 gagtctcact gtctcttgcc cacttcgtcc ttggctcaac ttctctgggt gtcaccattt
     1921 ctccgatctt ctctagaggt ctttgccccg tggccctgag tctctctctg aaccacctga
     1981 aatctgattt ctaactccta tgctgtgcct ggtatcccta caaatcacaa gacagagtgg
     2041 agtccgaggt cagctccgaa gtgaacactg aagtcagcac acagaggctg gaggagtagg
     2101 cactggagag acttgggcag gctgcaccgg atagccaacg tgctatcgcg cttctatcgc
     2161 gcttctgact gccagtctct gccctcctcc ctggttaggc agctgcccca gcacagagtt
     2221 gcgggagggg gcagttcctg gccccagtgg ctaccctggg gaccccaagc tccgccctac
     2281 tacactccta ttggcttgag gcgcccccgc ccccagcctc cctttccagc tcccgggctt
     2341 ttaggctagc ctggataaat agccccgggg ggcctggctc taagctaggg gccaggacac
     2401 cccaggacgc gactgctttc ttcaccacac ctctgacagg acaggacagg gagggaaggt
     2461 agaggacagc aggtgtgcat tccaaccgtc agaaccattg tcattgtact attggggttc
     2521 aggagtgaca gaaagttaag acgactcttc aggcttgggt tgagcgagaa gcaggaccca
     2581 gaactgggac atggagctac tatcgccgcc actccgggac acagacttgc taggccccga
     2641 cggctctctc tgctcctttg cgacacgcga tgacttctat gatgatccgt gtttcgactc
     2701 accagacctg cgcttttttg aggacctgga cccgcgcctg gtgcacgtgg gagccctcct
     2761 gaagccggag gagcacgcac acttccccac tacggtgcac ccaggcccag gcgctcgcga
     2821 ggatgagcat gtgcgcgcgc ccagcgggca ccaccaggcg ggtcgctgct tgctgtgggc
     2881 ctgcaaggcg tgcaagcgca agaccactaa cgctgatcgc cgcaaggcag ccaccatgcg
     2941 tgagcggcgc cgcctgagca aagtgaacga ggccttcgag acccttaagc gctgcacgtc
     3001 cagcaacccg aaccagcggc tacccaaggt ggagatcctg cgcaacgcca tccgctacat
     3061 tgaaggtctg caggctctgc tgcgcgacca ggacgccgct ccccctggcg ccgctgcctt
     3121 ctacgcacct ggcccgctgc ccccaggccg tggcagtgag cactacagcg gcgactcaga
     3181 cgcgtccagc ccgcgctcca actgctctga tggcatggta aggctgtgac caaggaggat
     3241 gacaagtgga ggcagcgcta gagtatctgc aaaacatttc caaggccctt ggggtggggg
     3301 tgtctttatg cccagatgct catggtatct gtcactggag tgtttggaga cccagggcat
     3361 ctatgattct gccaattaaa ggtgttatta gaaccctgct gcgcagaccc tgggatacgc
     3421 ttttcctcct caaatcctta ttaccctaat gcagattatt gttcttgggt gactgtccac
     3481 tctcagtttg gctctgcatg ggacagcttc caatgagtgc tggctcctac ctcctaaatg
     3541 gggctgcacc agtcctggac ccggcagcta acactaaggg agtgagggag gggtgatgac
     3601 aaggagtctt gcttgagacc cactcgggcc ctataggctg acttcgtccg tccttgctat
     3661 tcgcagatgg attacagcgg ccccccaagc ggcccccggc ggcagaatgg ctacgacgcc
     3721 gcctactaca gtgaggcgtc cagcggtgcg tattctcagc tgttcccaac tagcgggctc
     3781 tcatcggcct tccgtgtccc ccttgaaatt tttctctgtc cctaagcttg gtaccctctt
     3841 cccacctcca ccacataagc acccatatct tggggtgact gagggaagcg ttggggggtg
     3901 ggggagggga agaacctatg atatgcgcct ttcctctccc ttttcccttg cagtctagca
     3961 agtcctcagt ttcacttcta cctcaaagtt ccgtgcctag gggcaagaaa cttgagaaga
     4021 gacttaagtt ggattattaa ccttcccctc ccttcacaga gcccagacca gggaagagtg
     4081 cggccgtgtc gagcctcgac tgcctgtcca gcatagtgga gcgcatctcc acagacagcc
     4141 ccgctgcgcc ttcgctgctt ttgccagatg cgccaccaga gtcgcctccg ggtccgccag
     4201 aggagacatc ctcaagcgat gcagaacagg ggacccagac cccgtctccc gactccaccc
     4261 ctcagtgtcc tgcaggctca aagcccaatc cgatttacca ggtgctctga gaggttggct
     4321 gcagcagcag agggcgcccg gtctgcactc atggggatgg tgcccctggg tccttcatgc
     4381 ccccccaaaa atgaagctta aatgacactc ctcccaattg tcctttcaaa gccattcttc
     4441 cagagggaag ggaagagcag aagtttgttg tcctacatcc ggccccaagg aaaagacgaa
     4501 gtctggttgt tgttgctgct gctgttgttg ttgttgttgt tgttgttgtt gtagtcatgg
     4561 ggttttttgt ttgtttgttt tgtttttcat gcgactcaca gcgaaggcca cttgctgtcc
     4621 ctcactgggc cagagctgat ctttgagtgg ccaggacctc tttcctttcc tcacagtccc
     4681 tagcacaggg tgagcctcgc acacttaagc cctgccttcc acatccctgt tgtttgtgga
     4741 gacactgttc ccactttctg gagccccccc ccgacaccca ctctttccca cagcttgcga
     4801 ggccactcag atctcgggtg taacaggtgt aacaaccata ccccactctc tcccttccca
     4861 tgttcaggac cacttatttt ttttatatta agacttttgt aatctattcg tgtaaataag
     4921 agttgcttgg ccagagctgg agccccgtgg gctgtattta tctccgaggc atgctgtgta
     4981 gtgcaacaaa atctttgtat gtttattcct caagcgggcg aagcctcgag gctcattcgc
     5041 tcaggtgttg gaaataaaga tgctaattta tacaacagtg gctctggctt ttcctagggg
     5101 gatcagaaag aaactccaca aactgagcag actgtctccc agcgacccct gtaggtggta
     5161 gaagggtagc acagagactg ggtgctgctg ggtaatgaag gactaggcag acctccagct
     5221 gtaggagatt cctgaggcct tgctgctcct ccaaggaaac cagtgattgc agtggaaagg
     5281 tcgcagtagg ctgatgttag tttaaggata aaaaaggcgg acatgctggc tcatccctgc
     5341 aatctcagca cattcaagag gttgaggcag gaggatggct gcgagctgga ggccaccctg
     5401 gctagaaagt agaaaccctg ccctcaaaac aaatactctc tttaaaataa aaatgaaaac
     5461 tgagtgccga ggaggctcag ttgatagcgc actggcctag catgcacaaa atcccgcggc
     5521 gcgctcagtc cccagcacca tatagacctg ttatggcgga cacagctgca gtgtcaaagc
     5581 ccaggaggta gtacaggaaa atcagaagta catggtcatg ctcagctaca cagcaagttc
     5641 caggccagtc tgggatacat gaatccctgc caatagatgg attaattaat taagattccg
     5701 caagaatgaa tctgtccaga accagttatt gttgctttcc aaagatctcc ttttagggac
     5761 tctgaagtgt gtgctgagtt gagaatggtt cccgtccatg atgtgtgcag aaggcactgt
     5821 gggagctttt ggccctggag ccacacaata ccctcccaag ggtggagaag ggtgagatgc
     5881 tccagtgcaa gaagagacac ctacagggcc ctggggatgg gttctgaacc gtgtggtgca
     5941 tgcaagctct taagaatagt ggaactgcac agagacagca ccgtcagagc caacccttag
     6001 aatatctgcc actgtctcag ctcatcagaa ggtggaggct cagagcctgt ggggggaggg
     6061 aggggcgcct gggaccagcg tatctctaga gctgtggggc ttccctcagg ctgtgtagag
     6121 ggcaggggga ggccattggt gcagccggag tgcaaggcag gctttctgga caaagtgcta
     6181 tttcagatgt gtcgggggag acaagtgtag gcaatgtaca atggctgtga gggacacaca
     6241 cacacacaca cactacacac acacataaca caccacacac acacacacat acagacaccc
     6301 acagacacca cacacacaca cacacacaca cacacacact acagacacca cagacaccac
     6361 acacacacac acacacaggg acctctattc ttccctggaa tggcctggca caaattctct
     6421 gtccctttca cacttgtccc tagggcctca gtacctcctg tattccattt gtatagatct
     6481 ccttgaattc
//