From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: D.pseudoobscura Adh gene for alcohol dehydrogenase
Date: 28 Dec 92 21:26:20 GMT
Distribution: bionet
Checksum: 11659 8

LOCUS       DROADHGN07   3444 bp ds-DNA             INV       01-DEC-1992
DEFINITION  D.pseudoobscura Adh gene for alcohol dehydrogenase
ACCESSION   X62187
KEYWORDS    ADH gene; alcohol dehydrogenase.
SOURCE      Drosophila pseudoobscura DNA.
  ORGANISM  Drosophila pseudoobscura
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 3444)
  AUTHORS   Schaeffer,S.W. and Miller,E.L.
  TITLE     Estimates of gene flow in Drosophila pseudoobscura determined from
            nucleotide sequence analysis of the alcohol dehydrogenase region
  JOURNAL   Genetics 132, 471-480 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=BR3F; *source: isolate=Bryce Canyon, Utah; *source:
            chromosome=IV section 88;
               From EMBL    entry DPADHGN07;  dated 16-OCT-1992.
FEATURES             Location/Qualifiers
     mRNA            join(40..119,915..1020,1083..1487,1550..1965)
                     /note="adult mRNA (Adh)"
     mRNA            join(882..1020,1083..1487,1550..1965)
                     /note="larval mRNA (Adh)"
     promoter        8..14
                     /note="adult promoter (Adh)"
     prim_transcript 40..1965
                     /note="adult primary transcript (Adh)"
     exon            40..119
                     /note="adult exon 1a"
     intron          120..914
                     /note="adult intron"
     promoter        846..853
                     /note="larval promoter (Adh)"
     prim_transcript 882..1965
                     /note="larval primary transcript (Adh)"
     exon            882..1020
                     /note="larval exon 1"
     exon            915..1020
                     /note="adult exon 1b"
     intron          1021..1082
                     /number=1
     exon            1083..1487
                     /number=2
     intron          1488..1549
                     /number=2
     exon            1550..1965
                     /number=3
     polyA_signal    1942..1947
     polyA_site      1965
     CDS             join(928..1020,1083..1487,1550..1816)
                     /EC_number="1.1.1.1"
                     /gene="Adh"
                     /product="alcoholdehydrogenase"
                     /codon_start=1
                     /translation="MSLTNKNVVFVAGLGGIGLDTSRELVKRNLKNLVILDRIDNPAA
                     IAELKAINPKVTITFYPYDVTVPVAETTKLLKTIFAQVKTIDVLINGAGILDDHQIER
                     TIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGSKAAVVN
                     FTSSLAKLAPITGVTAYTVNPGITKTTLVHKFNSWLDVEPRVAEKLLEHPTQTSQQCA
                     ENFVKAIELNKNGAIWKLDLGTLEPITWTQHWDSGI"
BASE COUNT      964 a    789 c    788 g    903 t
ORIGIN      
        1 cctagtgtat ttaaggcact gcacatgtcg aggaccacga ttattgtcta cagtgcagtc
       61 agtagttgtc aggtgcagca ggcggaccag catttcttta aatctactca atcgatcaag
      121 taagtaactg taatccaagt acagtcggcc catcccactc ggttctgccg taactcaaga
      181 aatttcttga tagcgcagtt ccagttgtag aacgtcgttt aaaaaaacat ctcgttggag
      241 cttgggttga aaaacgttcg agttgggcgt agaaaagtta aaatataaaa tatcaaaaaa
      301 gagaaaatat cttcccaaag cagctgtcca ttttttgtta aagtgataga tcaaaaattc
      361 gtatgacgta tttcccaagt gctctttatg caaataattt cctcaattct aattctacaa
      421 gaagcacttt tggctcttgt ccagaaaaaa caatttgttt acacttgtcg gatgataaca
      481 taagcggacc gacggctaag taacataaca gtcgcctgtt aagtaatgcc ctcactcgct
      541 gttagatggc cgcgcgtgtc gactccgata gaccagcaga cacgcagtag ttttcctcaa
      601 gaacctgaac tctaaacata gacataattt acgatacctt gagactcaaa taaaaataca
      661 agtatgagtg gtattctatt cctgattaga ctcgcacaca cacacgtacg agtattaaca
      721 taaatttgcc ggcaaataac caaaacaaaa cgaacgcaaa cgatccgaac acgtaatgcg
      781 agagataaga aacagaaaag ctcgacgtga aagaagcttc tggcggaagc tcttgccgaa
      841 ctccctataa atacgagaca gaaaaccaga ataaatataa taacaaactg ttgaattgtc
      901 ccatcgattc ccagatcaaa agacagaatg tctctcacca acaagaacgt cgttttcgtg
      961 gccggtctgg gcggcattgg cctggacacc agccgggagt tggtcaagcg taatctgaag
     1021 gtaagagaga acgaattcca tggaatctat ggaatcctaa attaaaaatt tatatttttt
     1081 agaacctggt catcctggat cgcattgaca atccggctgc cattgccgaa ctgaaggcaa
     1141 tcaatcccaa ggtgaccatc accttctatc cctacgatgt gactgtgccc gtcgctgaga
     1201 ccaccaagct cctgaagacc atctttgccc aggtgaagac catcgatgtc ctgatcaacg
     1261 gtgctggcat cctggacgat catcagatcg agcgcaccat tgccgttaac tacacgggcc
     1321 tggtcaacac caccacagcc attctggact tctgggacaa gcgcaagggc ggcccaggcg
     1381 gcatcatttg caacattggc tccgtcaccg gtttcaatgc catctaccag gtgcccgttt
     1441 actccggctc caaggcggcg gtggttaact ttacctcctc cctggcggta agaaatccta
     1501 caactatcct aactatccca aaactaaata tttctttgaa attccataga aactggctcc
     1561 cattactggt gtcactgctt acactgtcaa tcctggcatc actaagacca ctctggtcca
     1621 caaattcaac tcgtggctgg atgtggagcc ccgtgtggcg gagaagctgc tcgagcatcc
     1681 cacccagacc tctcagcagt gcgccgagaa ctttgtgaag gccattgagc tgaacaagaa
     1741 cggtgccatc tggaagttgg atttgggcac cttggagccc atcacatgga cccagcactg
     1801 ggactcgggc atctaaacca tcccagagac tctatgggac atggcgtttt agcttttagt
     1861 ttcttttttt ccactcaatt gttacgtata tacatacaca tatggcaata aggctgattt
     1921 gaaccccgtt ttgaatatga taatacaaaa ttatatttga gaaatttcaa caaaatcgat
     1981 aagagctata gctctctttt aattaaaaaa aaactagata aaaagagcaa tggtcgtcag
     2041 tggtggtcag tggtcgttgt ggcctctatc gatttccaca caaaaacttt actgtttagt
     2101 aatagaaaag aacttgagaa aggcagccaa aagaatgtac gatctgacgg gtaagcatgt
     2161 ctgctatgtg gctgactgcg gtggcattgc actggagacc agcaaggttc tcatgaccaa
     2221 gaatatagcg gtgagtggta gagtggtgta gagagtggag agtgttccga agtgattctg
     2281 gttcttaaac aagtctctag tctctagtct ctagtctctt ggctgctgct ggtagctgtc
     2341 gaaactaatt aagttaatga ctttttcatg ttttgttttt gtccgctgac ttttgctgtt
     2401 caaagctaca attaagttta tgttttgagt ttgatctact tttgcttaag ggaaggaatg
     2461 tgcatcatat catattgatt ccatcttgat tctttgccca gaaactggcc atccttcaga
     2521 gcgtggaaaa ccccccggcc atcgctcagt tacaatcgat taagcacagc acacagatct
     2581 tcttctggac cttcgatgtg accatggccc gcgaggagat gaagaagtac ttcgatgagg
     2641 tcatggtcca gatggactac atcgatgtac tgatcaatgg ggccaccctg tgcgatgagc
     2701 ggaacattga tgccaccatc aatacgaatc tgaccggcat gatgaacacc gtggccactg
     2761 tgctgcccta tatggaccgt aagatgggcg gttcgggtgg actgattgtg aatgtcacct
     2821 ccgtcatagg actggatcca tcgccggtct tttgtgcgta cagtgcctca aagtttggtg
     2881 tgattgggtt cacccgaagt ctagcggtga gtgggcgaga tcttaacttg aaaatcctct
     2941 ctaatgtctt ccattctttc gcaggatccc ctgtattaca cccaaaatgg tgtggctgtc
     3001 atggccgtct gctgtggtcc caccaaagtg tttgtcgatc gggaactgac tgccttcctg
     3061 gaatacggcc agtcctttgc cgatcgcctg cgtcgtgccc cctgccaatc gacggccgtc
     3121 tgcggccaga atatagtaaa tgccatcgag agatcggaga acggacagat atggattgcc
     3181 gacaagggcg gcctggagtc ggtggccctc cactggtatt ggcatatggc cgatcagttt
     3241 gtgaactata tgcagagcac tgacgatgag gatcaggagt tttttttggg ccagcgatga
     3301 ggcatgcctt gatccacgga ataaaacatc aaatgtgcca caaaaagtag gcaacttgtt
     3361 tgtgggtctg gaaatagatt tgaaatattt tgaggtcata tgaataatga cataaatgag
     3421 ggtgcctgaa agtatgccaa gttt
//