From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase
Date: 3 Jan 93 22:21:39 GMT
Distribution: bionet
Checksum: 44429 5

LOCUS       S115387      1665 bp    mRNA            PRI       24-NOV-1992
DEFINITION  3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase
            [human, skin, mRNA, 1665 nt]
ACCESSION   S45679
KEYWORDS    .
SOURCE      human skin
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Dumont,M., Van,L.T., Dupont,E., Pelletier,G. and Labrie,F.
  TITLE     Characterization, expression, and immunohistochemical localization
            of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in
            human skin.
  JOURNAL   J. Invest. Dermatol. 99, 415-421 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 115387] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 1.  The authors begin their numbering
            at -131.  Zero is not present in the numbering.
FEATURES             Location/Qualifiers
     CDS             132..1253
                     /note="3 beta-HSD;  For the protein sequence (NCBI gibbsq
                     115388):  Method: conceptual translation supplied by
                     author.  This sequence comes from Fig. 1."
                     /product="3 beta-hydroxysteroid dehydrogenase/delta
                     5-delta 4 isomerase"
                     /codon_start=1
                     /translation="MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELR
                     EEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNV
                     KGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKK
                     LAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKF
                     STVNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEF
                     GLRLDSRWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKA
                     QRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ"
BASE COUNT      442 a    415 c    388 g    420 t
ORIGIN      
        1 actcttctgt ccagctttta acaatctaac taatgccctc tccagggtca ccctagggtc
       61 accctagaat cagatctgct ccccagcatc ttctgtttcc tggtgagtga ttcctgctac
      121 tttggatggc catgacgggc tggagctgcc ttgtgacagg agcaggaggg tttctgggac
      181 agaggatcat ccgcctcttg gtgaaggaga aggagctgaa ggagatcagg gtcttggaca
      241 aggccttcgg accagaattg agagaggaat tttctaaact ccagaacaag accaagctga
      301 cagtgctgga aggagacatt ctggatgagc cattcctgaa gagagcctgc caggacgtct
      361 cggtcatcat ccacaccgcc tgtatcattg atgtcttcgg tgtcactcac agagagtcta
      421 tcatgaatgt caatgtgaaa ggtacccagc tcctgttaga ggcctgtgtc caagctagtg
      481 tgccagtctt catctacacc agtagcatag aggtagccgg gcccaactcc tacaaggaaa
      541 tcatccagaa tggccatgaa gaagagcctc tggaaaacac atggcccgct ccatacccac
      601 acagcaaaaa gcttgctgag aaggctgtac tggcggctaa cgggtggaat ctgaaaaacg
      661 gcggcaccct gtacacttgt gccttacgac ccatgtatat ctatggggaa ggaagccgat
      721 tcctttctgc tagtataaac gaggccctga acaacaatgg gatcctgtca agtgttggaa
      781 agttctccac tgttaaccca gtctatgttg gcaatgtggc ctgggcccac attctggcct
      841 tgagggccct gcaggacccc aagaaggccc caagcatccg aggacagttc tactatatct
      901 cagatgacac gcctcaccaa agctatgata accttaatta caccctgagc aaagagttcg
      961 gcctccgcct tgattccaga tggagctttc ctttatccct gatgtattgg attggcttcc
     1021 tgctggaaat agtgagcttc ctactcaggc caatttacac ctatcgaccg cccttcaacc
     1081 gccacatagt cacattgtca aatagcgtat tcaccttctc ttataagaag gctcagcgag
     1141 atctggcgta taagccactc tacagctggg aggaagccaa gcagaaaacg gtggagtggg
     1201 ttggttccct tgtggaccgg cacaaggaga ccctgaagtc caagactcag tgatttaagg
     1261 atgacagaga tgtgcatgtg ggtattgtta ggagatgtca tcaagctcca ccctcctggc
     1321 ctcatacaga aagtgacaag ggcacaagct caggtcctgc tgcctccctt tcatacaatg
     1381 gccaacttat tgtattcctc atgtcatcaa aacctgcgca gtcattggcc caacaagaag
     1441 gtttctgtcc taatcatata ccagaggaaa gaccatgtgg tttgctgtta ccaaatctca
     1501 gtagctgatt ctgaacaatt tagggactct tttaacttga gggtcgtttt gactactaga
     1561 gctccatttc tactcttaaa tgagaaagga tttcctttct ttttaatctt ccattccttc
     1621 acatagtttg ataaaaagat caataaatgt ttgaatgtta aaaaa
//