From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse Golli-mpb mRNA, complete cds (alternate transcript from clone
Date: 29 Dec 92 01:20:07 GMT
Distribution: bionet
Checksum: 46910 6

LOCUS       MUSGOLLIA    2490 bp ss-mRNA            ROD       07-DEC-1992
DEFINITION  Mouse Golli-mpb mRNA, complete cds (alternate transcript from clone
            J37.)
ACCESSION   L07507
KEYWORDS    alternative splicing; myelin basic protein; overlapping genes.
SOURCE      Mus musculus (strain C57BL/6) (library: gt11) 15 day brain cDNA to
            mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (sites)
  AUTHORS   Takahashi,N., Roach,A., Teplow,D.B., Prusiner,S.B. and Hood,L.E.
  TITLE     Cloning and characterization of the myelin basic protein gene from
            mouse: One gene can encode both 14 and 18.5 kd MBPs by alternate
            use of exons
  JOURNAL   Cell 42, 139-148 (1985)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   de Ferra,F., Engh,H., Hudson,L., Kamholz,J., Puckett,C.,
            Molineaux,S. and Lazzarini,R.A.
  TITLE     Alternative splicing accounts for the four forms of myelin basic
            protein
  JOURNAL   Cell 43, 721-727 (1985)
  STANDARD  full automatic
REFERENCE   3  (sites)
  AUTHORS   Newman,S., Kitamura,K. and Campagnoni,A.T.
  TITLE     Identification of a cDNA coding for a fifth form of myelin basic
            protein in mouse
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 84, 886-890 (1987)
  STANDARD  full automatic
REFERENCE   4  (bases 1 to 2490)
  AUTHORS   Campagnoni,A.T., Pribyl,T., Campagnoni,C., Kampf,K.,
            Amur-Umarjee,S., Landry,C., Handley,V., Newman,S., Garbay,B. and
            Kitamura,K.
  TITLE     Structure and developmental regulation of Golli-mbp, a 105 Kb gene
            that overlaps the myelin basic protein gene and is expressed in
            cells in the oligodendrocyte lineage in the brain
  JOURNAL   J. Biol. Chem. (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             258..1010
                     /standard_name="J37 transcript"
                     /gene="Golli-mbp"
                     /evidence="EXPERIMENTAL"
                     /note="alternate"
                     /codon_start=1
                     /translation="MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSD
                     VFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGR
                     EDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQRSKYLATASTMDHARHGF
                     LPRHRDTGILDSIGRFFSGDRGAPKRGSGKDSHTRTTHYGSLPQKSQHGRTQDENPVV
                     HFFKNIVTPRTPPPSQGKGGRDSRSGSPMARR"
BASE COUNT      581 a    731 c    679 g    497 t      2 others
ORIGIN      
        1 agcactggga ggcggggcgg gagcggggtg cgcgcccgtc cccggagcag ccgctgtcag
       61 tcaccgccgc tgcgcgccag ggaggaccag cctctggctc aggcggcctg agcttcacga
      121 ccccggaaca tagtatccgc gccccagcga cccctagccc agcgttgggt cccatccgcc
      181 gggatcccgg gatcctgggc ccctcttggc ctccgagcag cagccagcac cactcttgaa
      241 caccccattg ggtcgccatg ggaaaccact ctggaaagag agaattatct gctgagaagg
      301 ccagtaagga tggagagatt caccgaggag aggctggaaa gaagagaagc gtgggcaagc
      361 tttctcagac ggcctcagag gacagtgatg tgtttgggga ggcagatgcg atccagaaca
      421 atgggacctc ggctgaggac acggcggtga cagactccaa gcacacagca gacccaaaga
      481 ataactggca aggcgcccac ccagctgacc cagggaaccg cccccacttg atccgcctct
      541 tttcccgaga tgccccggga agggaggaca acaccttcaa agacaggccc tcagagtccg
      601 acgagcttca gaccatccaa gaagacccca cagcagcttc cggaggcctg gatgtgatgg
      661 catcacagaa gagaccctca cagcgatcca agtacctggc cacagcaagt accatggacc
      721 atgccaggca tggcttcctc ccaaggcaca gagacacggg catccttgac tccatcgggc
      781 gcttctttag cggtgacagg ggtgcgccca agcggggctc tggcaaggac tcacacacga
      841 gaactaccca ttatggctcc ctgccccaga agtcgcagca cggccggacc caagatgaaa
      901 acccagtagt ccatttcttc aagaacattg tgacacctcg aacaccacct ccatcccaag
      961 ggaagggagg aagagacagc cgctctggat ctcccatggc gagacgctga gagccctccc
     1021 cgctcagcct tcccgaatcc tgccctcggc ttcttaatat aactgcctta aacttttaat
     1081 tctacttgca ccgattagct agttagagca gaccctctct taatcccgtg gagccgtgat
     1141 cgcggtgggg ccagnncacg gcaccccgac tggttaaaac tattcgtccc ttttcgtttg
     1201 aagattgagt tttctcgggg tcttctcagc cctgacttgt tccccgtgca gcttgttcga
     1261 ctccggaggt tcaggtgcac ggacaccctt ccaagttcac ccctactcca tcctcagact
     1321 tttcacggtg aggcacaccc ctccagcttc cgtgggcact gcggatagac aggcacaccg
     1381 ccaaggagcc agagagcatg gcgcagggga ctgtgtggtc caggcttcct ttgttttctt
     1441 ccccctaaag agctttgttt ttcctaacag gatcagacag tcttggagtg gcttatacaa
     1501 cgggggcttg tggtatgtga gcacaggctg ggcagctgtg agactccaga gtggggtggc
     1561 cccggggaca cttccaggcc agctatcccc tgcaccccac cagctgattt cgagcgtggc
     1621 agagggaagg aaaggggcga gtgggctggg caatggcccc aacaggaaac ggggacttag
     1681 gagaacacgc tggacatatg tgtggccgcc aaatgtcacc atctctcctc agtggctccc
     1741 cagagctggt gcttttaaga accctgtttc ctctcagagc ccagggagag tccaaggaca
     1801 tggcgcatct ggaagtggga ctgcaggagt tctctggtgg cctcgtgctg tccctctggc
     1861 cacttctcat ggtggggtgg tcagcggcag ctcgccatgg cagtgcccat tggtacacac
     1921 taacctcggt ggaaaaataa ccattccctg cctcctagaa aggactcatt cttagcttta
     1981 ggggggttcc tgtcactgaa tcgagtcgct gccctggatg cagggctggc ctgggcgacg
     2041 ctccagggat gaggagctga gaaccccagt ctaataatgt ccatcgacac ctccttatcc
     2101 ctctaacgta ctatgtcttt tgatttagca tgccttctgt agaccttcca aagagcccca
     2161 cactggcacc gtcaccccta ggaaggcagg tgatggttga tgtagcccaa tactgcatct
     2221 tgttaatctg ttctaactcc gagtagagtg tgggtttaag ataacaccga ttaatgtatc
     2281 gccacaataa cgtgagggta agagaaaaag cagggaagaa atttccagaa aaaaaccctc
     2341 cagattgtcc caccggagtg tttgccctcc agtgtgactg actgaacgac cttgcccatg
     2401 gcttcgtcca gacagcgcag ctgcagtatg gctggacaga agcacctact attcttgaat
     2461 attgaaataa aataataaac ttgcaaaaaa
//