From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus MMCP-1 gene for mast cell protease 1
Date: 28 Dec 92 21:30:30 GMT
Distribution: bionet
Checksum: 25488 9

LOCUS       MUSMMCP1A    4338 bp ds-DNA             ROD       01-DEC-1992
DEFINITION  M.musculus MMCP-1 gene for mast cell protease 1
ACCESSION   X68803 X62803
KEYWORDS    mast cell serine protease; serine protease.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Huang,R., Blom,T. and Hellman,L.
  TITLE     Cloning and structural analysis of MMCP-1 MMCP-4 and MMCP-5, three
            mouse mast cell-specific serine proteases
  JOURNAL   Eur. J. Immunol. 21, 1611-1621 (1991)
  STANDARD  full automatic
COMMENT     *source: strain=Balb/c; *source: tissue=liver; *source:
            clone_library=pWE15 Cosmid;
               From EMBL    entry MMMMCP1A;  dated 19-OCT-1992.
FEATURES             Location/Qualifiers
     mRNA            join(1344..1433,1941..2091,2395..2530,2729..2983,
                     3376..3771)
                     /gene="MMCP-1"
     mat_peptide     join(1946..2091,2395..2530,2729..2983,3376..3516)
                     /product="serine protease"
                     /gene="MMCP-1"
                     /codon_start=1
     TATA_signal     1316..1322
                     /gene="MMCP-1"
     exon            1344..1433
                     /number=1
                     /gene="MMCP-1"
     sig_peptide     1379..1432
                     /gene="MMCP-1"
     intron          1434..1940
                     /number=1
                     /gene="MMCP-1"
     exon            1941..2091
                     /number=2
                     /gene="MMCP-1"
     intron          2092..2394
                     /number=2
                     /gene="MMCP-1"
     exon            2395..2530
                     /number=3
                     /gene="MMCP-1"
     intron          2531..2728
                     /number=3
                     /gene="MMCP-1"
     exon            2729..2983
                     /number=4
                     /gene="MMCP-1"
     intron          2984..3375
                     /number=4
                     /gene="MMCP-1"
     exon            3376..3771
                     /number=5
                     /gene="MMCP-1"
     CDS             join(1379..1433,1941..2091,2395..2530,2729..2983,
                     3376..3519)
                     /gene="MMCP-1"
                     /product="serine protease"
                     /codon_start=1
                     /translation="MQALLFLMALLLPSGAGAEEIIGGVEARPHSRPYMAHLKIITDR
                     GSEDRCGGFLIAPQFVLTAAHCKGREITVTLGAHDVSKSESTQQRIKVEKQIIHKNYN
                     VSFNLYDIMLLKLEEKAELTPTVDVIPLPGPSDFIDPGKMCWTAGWGKTGEKEPTSET
                     LREVELRIMDKEACKMYKHYDYNFQVCVGSSTKLKTAYMGDSGGPLLCAGVAHGIVSY
                     GDSHGKPPAVFTRISAYVPWIKTVINGK"
BASE COUNT     1142 a   1044 c    913 g   1239 t
ORIGIN      
        1 tctgagctgt ctggtccaag catgggaact agctgaggct tcataagata gtcaatgcct
       61 ctagaaattt tctgcaaagc ttcatgattc tagaacatca agtccaatta tatggttcat
      121 tgagatgcac agtctttgag tgtgaacaag tgcttgtgtg ggttactaca ttactctagc
      181 tgcataatat ctttttcttt gaaatttcat cctaataaat tgtttttatt catagaaaat
      241 ttttcattct catattgaac caaaaataat gtccaaaaca atcaccttct tcgactctgt
      301 tttgagtact tgaacacaat gagccaatca ctgtgcactc ttatgatctc tggctatgaa
      361 tacttaatcc cccaaagcct cgtgttgcat tgcagattcc caagatcttt tattttgtga
      421 tattctgaaa ttccattgaa tcctccctca atatgtatta caatgtctac caaagagact
      481 attcgtatga ttaaatcagg acatttactt atagtagctg ttctcaacct gtgggtcatt
      541 gaccccttta ggggtcaaat atcagatatc ctgcatatta cgaatttcct gttaaaattc
      601 ataaccatag caatattaaa gttataaagt agcaatgaat taattttgtt ggtggggtta
      661 ccataatatg atcagtactg gccatattgg caccacaatg gctccattta ataactgtat
      721 taaaaggtca gaccattagg aatgttggga accactgact taattaaggt gttggtcatg
      781 ccttacatgc tgtgtattca atacactctc cccacacctt catccctcac agccacattc
      841 tatcatgtcc tacttatttg aataaggatg agatgccctc aaagtgttca acagaaacaa
      901 tggcctgcag gctaaattag ccctccatca gtttttgttt tttaaataaa atatatgtcc
      961 tctcctccat gtgctcatac actacagatg cccgtgtttg tgtttaagca gcagaggtga
     1021 gacttcacac gtatgcagca tgggtctcaa agctgacaaa aatacctgga tgcttagaag
     1081 aaccattcca tgatccctga tcaaggtccc cctccctttg tgttgctgcc ctgcttcctg
     1141 ggagccactt tgaaggatgc acttaccacg tcattgtggg atccaggagt gtcaagacct
     1201 agccacagac tcagaaccac cagtggtcag agtatgagaa tttctgataa ggaaaataag
     1261 gcttgtccaa gccagatctg tggttcccag ccctgccttt ctcccacgtt ggatctataa
     1321 aagcaggaac caggacagcc acaccctaga agctcaccaa ggctgcacca ctggcaaaat
     1381 gcaggcccta ctattcctga tggcacttct cttgccttct ggagctggag ctggtgagtt
     1441 tcgtcctcat ttccctagct tccgagtttc agccgggaac cataatctgt tagctttggt
     1501 aaaagagacc ctaagataag gcagggtcct aaattgaggt agtccagggg aaatctctag
     1561 atcaaagaag aatgaaaaac taactcttct tcacaccatt tcatcaaaat actctctgtt
     1621 ctgataggca gctcttctct ggccttcctt tagtgttgag ggagaccaga tgagtgtgtg
     1681 gagaaaagtc taatgatgtt gaaagtcaga aacaagaatg gtcattgtgt tctgaatgaa
     1741 ggatgatggt ggacatggag acctggggag gaaatatcaa caggggagaa aagaccaaag
     1801 gacatgtgga agttcctgat ccccactcga ggtgggatgg gcttagagta gtcgctcagt
     1861 tttaccgcat cttcccttgc tggtgctgtg ttggggtgtt ccacatgttt gtgaccaggg
     1921 actggggttc tttgttccag aggagattat tggtggtgtt gaggctagac cacactcccg
     1981 tccttacatg gcccatctga agatcatcac ggacagaggt tctgaggaca gatgtggtgg
     2041 gtttctcata gccccccaat ttgtgttgac tgctgcacac tgtaaaggaa ggtaagaggt
     2101 ttctctttct gtgaggaaat gcaggagcca gagtcccaga gcagcagagg cctgaggaag
     2161 tctctgagcc ctgctcatct gcagatgggc tctccttaca cagagaggaa aaggtgtggg
     2221 gagagttctc attcctatgt tttcctgagt cctgtcgttc taggcacgct gtggtccatc
     2281 tcaagagtga ccaggggctc tactctgggc tcaagaagaa agaccctggt gcccctcacc
     2341 ttggaatgag tcctcctcat aagacttttc actgcctctt ttctctttca acagagaaat
     2401 cactgtcacc cttggagctc atgatgtgag caagagtgaa tccacacaac agaggataaa
     2461 agtcgaaaaa caaatcattc acaaaaatta caacgtctct ttcaatctct atgacatcat
     2521 gttactgaag gtgcctttct ttttctggct ctgcttaagc ctcccctctt taactctctc
     2581 ccggcttagg actttgaaca ctctcttgtc caatcctttt cctcagaacc taatcctgaa
     2641 ttctatgcca ttatagaccc actgggaaag gatccatgtc caagcatcct tctctggttt
     2701 gccatctctt ctttctttct cccaacagct tgaagagaaa gctgagttga ctcctactgt
     2761 ggatgtaatt cccttgcctg gtccctctga ctttatcgac cctgggaaga tgtgctggac
     2821 agctggctgg gggaaaactg gagagaaaga acctacctca gaaaccctga gagaggttga
     2881 actgagaatc atggataaag aggcctgtaa aatgtataag cattatgact ataacttcca
     2941 ggtctgtgtg ggaagttcca caaagttaaa aacagcatac atggtgagta cacacttgtg
     3001 tttcctcact acatcatgag acagcatcag tgggggaagt gtgccaaaca gctctccatg
     3061 gcagtgacta atacctgtgt tcttaggctt ctactctcga gactctggga actgatattc
     3121 tcccttcttt ctcaactccc tatgcccaag ccctgctcac aaccttccca tgaggttcca
     3181 gaagagaaag gatgggagta aagggagaca tgttagcact gggacaagga cagtgggtag
     3241 ggaatcaggc agtaaatctc taacttcaga ctctagacag acaggacctc atacaccatt
     3301 ccatgttaga tttttttgag ctcatattta ggggaaagaa atttttgttc atattctgat
     3361 ttttcttact tacagggaga ctctggggga cctcttctgt gtgctggtgt ggcccatggt
     3421 attgtatctt atggggattc acatggaaag ccccctgcag tcttcaccag aatctctgca
     3481 tatgtgccct ggattaaaac agtcataaat ggcaagtagc tgagaagtct gaccagcctg
     3541 agacagattc tccaagccag agctctctgg tactctttgt gttcaacaaa gcttgtcccc
     3601 agactatccc cagtctgccc ccagcctcac cccagcctat gtgcagcctg cctttagctt
     3661 gcccccattc tgtccccagc tgtccctttg aggatctcaa agatacagga gtctgtgatg
     3721 atggtttgtt ccctgtaatg cacctcaata aagacctaac ctccagcagc tgtgtgactc
     3781 cactctgggc tctaaacacc ccatcccttt tctaagcaca ataaagaatt gatttgagct
     3841 actatttttc catgttaact aacttgactc ctgacatcct ggtacagggt gtgtcacttt
     3901 ggattattga atattatcta acacgcacgg ctgtgaacag taagatttaa cacccagggt
     3961 aatatgcact gttttgttct tccctccact gtcctgcctt ctcatcttct ccctcctcgt
     4021 ctctcagctc ttctgcccac aaaccccatg ccttagccac tttccacaca tcatagcaga
     4081 ctctatgcct aggtcagaca tggctgctga tccttgtgtc ctcaccacct accctgccat
     4141 caccatcctc tcagtattgc acctgcagct agagcagagc ctgccttcag aagtccttgg
     4201 agcatgactg tggctgtagc agtcttaaca ggagagcatc agaactttct gaaccaaaca
     4261 cagggcagaa ctagcccatg atgggaagag accctctagt acttagcatg tactagtatt
     4321 tagcatggtg gctctaga
//