From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens TCR V-beta 6.10 gene for TCR beta chain variable region
Date: 29 Aug 92 10:01:53 GMT
Distribution: bionet
Checksum: 19919     5

LOCUS       HUMTRVB610   1782 bp ds-DNA             PRI       29-AUG-1992
DEFINITION  H.sapiens TCR V-beta 6.10 gene for TCR beta chain variable region
ACCESSION   X61444
KEYWORDS    T-cell receptor; T-cell receptor beta-chain variable region;
            TCR V-beta 6.10 gene.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1782)
  AUTHORS   Li,Y., Szabo,P. and Posnett,D.N.
  TITLE     Human Tcr V beta 6.10 is a pseudogene with Alu repetitive sequences
            in the promoter region
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
COMMENT     *source: tissue=placental; *source: clone_library=human genomic
            library; *source: clone=#11; *source: isolate=human genomic
            library, Clontech labs., CAT# *source: HL1067J; *source:
            chromosome=7; *source: is_germline=Y;
            From EMBL    entry HSTRVB610;  dated 30-OCT-1991.
FEATURES             Location/Qualifiers
     CDS             join(1135..1183,1324..1621)
                     /partial
                     /gene="TCRB"
                     /codon_start=1
                     /translation="MGTRLLCWAAICLLGADHTGAGVSQSLRHKVAKKGKDVALRYDP
                     ISGHNALYWYRQSLGQGLEFPIYFQGKDAADKSGLPRDRFSAQRSEGSISTLKFQRTQ
                     QGDLAVYLCASSSA"
                     /partial
     promoter        1..1134
     repeat_region   388..936
                     /rpt_family="Alu"
     exon            1135..1183
                     /number=1
                     /note="first leader"
     intron          1184..1323
                     /number=1
     exon            1324..1621
                     /number=2
                     /note="second leader and V region"
BASE COUNT      440 a    414 c    486 g    442 t
ORIGIN
        1 aaaacacgta gttgtcacca aggtatcctt tctgaattat agttaacaaa gatggaagtg
       61 gtcccagaag aggggcatga ggtgccgctc gtgagggaac catgtgatgg gacagcccat
      121 tgggcacgtg tgactggggg gatggaggag gctggggcat caatggggat ggcacagggg
      181 actctgactt gcaggaaaga caatgagctc caccttttgg tgctttgtgt tggcggacgt
      241 gttgacacat cctagagaac atgcccagca gacagaggag cggctgtggg atgaggagat
      301 aaactcagag atgcagcgtg aggcctccgg gtccagacag catgagagcc caaagcgatg
      361 atacatgcat tgatgttgtt aaaaaggatt tttttttttt tttgagacag attctcgctc
      421 tgtcgcccag atctggagta cagtggcgaa tctcggctca ctgcaagctc cgcctcccgg
      481 gttcaagcca ttctcctgcc tcagccctcc caagtagctt ggactagagg cgcccgcaca
      541 acgcctggct cattttttgt atttttagaa gagacagggt ttcaccatat tagccaggat
      601 ggtctcgatc tcctgacctc atgatccact gcctccgcct cccaaggcct gggctcacgc
      661 ctgtatccca gcactttgga gaccaaggtg ggcggatcac ttgaggtcat gagtttgaga
      721 ccagccgggg caatgtggtg aaaccccgtc tctactaaaa tacaaaatta gctggtatgg
      781 tggtgtgagt ctgtaatccc agctactcag gaggctgagg caggaggatc acttgaactt
      841 gggaggcaga gtttgcagtg agccgagatc acactgctgc actcattctg ggcaatggag
      901 caaggctctg tctcaaagaa caaacaagca aaaagcaagg aactcataaa tatttaaagg
      961 aggcatttaa gtaggtccta aaataaatcc tttgttcctg tcattgcgtg gattgagaga
     1021 ggatgtgatg tcactatggg accttctgtg tgggaacaag gacatccctc ctcctctgct
     1081 cctactcaca gtgactctga tctggtaaag ctcccatcct gccctgaccc tgccatgggc
     1141 acaaggctcc tctgctgggc agccatatgt ctcctggggg caggtgattc ctcagatgcc
     1201 aagcagtctc ctgtgtgtgt gtgtgtgtgt gtgtatgtgt gtgagatgtg tgtgtgagag
     1261 agagagagag agagctgact atagttgttt ttctcattca gttcccaatt tctgtctcca
     1321 cagatcacac aggtgctgga gtctcccagt ccctgagaca caaggtagca aagaagggaa
     1381 aggatgtagc tctcagatat gatccaattt caggtcataa tgccctttat tggtaccgac
     1441 agagcctggg gcagggcctg gagtttccaa tttacttcca aggcaaggat gcagcagaca
     1501 aatcggggct tccccgtgat cggttctctg cacagaggtc tgagggatcc atctccactc
     1561 tgaagttcca gcgcacacag cagggggact tggctgtgta tctctgtgcc agcagctcag
     1621 ccacagcact actgctccag tgtcagcttg gttccctagg aaatggggtt tctagaacct
     1681 gaatgctgac aaataagagt tgtatatgtg tataccatgc aacctgcgtt taaaaatgta
     1741 tgtacatagt gcaatgacta aatctagcct agttaacata tc
//