From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Streptomyces thermotolerans carbomycin-resistance protein (carA)
Date: 12 Sep 92 10:03:52 GMT
Distribution: bionet
Checksum: 02635     5

LOCUS       STMCARA      2393 bp ds-DNA             BCT       12-SEP-1992
DEFINITION  Streptomyces thermotolerans carbomycin-resistance protein (carA)
            gene, complete cds.
ACCESSION   M80346
KEYWORDS    carA gene; carbomycin resistance protein.
SOURCE      Streptomyces thermotolerans DNA.
  ORGANISM  Streptomyces thermotolerans
            Prokaryotae; Firmicutes; Streptomycetaceae.
REFERENCE   1  (bases 1 to 2393)
  AUTHORS   Schoner,B.E., Geistlich,M., Rosteck,P., Rao,R.N., Seno,E.,
            Reynolds,P., Cox,K., Burgett,S. and Hershberger,C.
  TITLE     Sequence similarity between macrolide resistance determinants and
            ATP-binding transport proteins
  JOURNAL   Gene 115, 93-96 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             411..2066
                     /product="carbomycin resistance protein"
                     /gene="carA"
                     /codon_start=1
                     /translation="MSTAQLALHDITKRYQDHVVLDRIGFTIKPGEKVGVIGDNGSGK
                     STLIKLIAGREQPDNGAVTVVAPGGVGYLAQTLELPLEATVQDAVDLALADLRELEEG
                     MRRTEAELAERPYQTGQDPELAGLLESYAALVDRYQARGGYEADSRVEIALHGLGLPG
                     LERGRRLGTLSGGERSRLALAATLASEPELLLLDEPTNDLDDRAVDWLEEHLRKHKGT
                     VVAVTHDRLFLDRLTTTILEIDSGKVMRYGNGYEGYLAAKAAERQRRLLEYEQWRAEL
                     DRSRDLIASNVARLDAIPRKLPFAVFGAGQFRMRGRGHGAMVRIRNAKERVARLTENP
                     VAPPPEPLTFTAEITTEAAQSRETVAELTGVRVGDRLSVDSLHLGPGERLLVTGPNGA
                     GKTTLLRVLSGELEPDSGSLLVSGRVGHLRQEQTPWRPGMTVLQAFSSGRAGDIDEHT
                     EALLSLGLFSPDDLRQRVQDLSYGQRRRIELARLVTEPVDLLLLDEPTNHLSPALVEE
                     LEEALTGYQGTVVVVTHDRRMRSRFNGAHLTLQDGRVAEFTAA"
BASE COUNT      379 a    823 c    878 g    313 t
ORIGIN
        1 aggccggatg tcgccgaccc ggaacgtact ggtcgacggc tgctggccgc ggaaccgaac
       61 tcgatccggt ctccgcgcgc accggagacg gcatcgaggc actgcgggac tacatcgacg
      121 tccttgccgc atcccgaggt ggagatcgag gccatggtgc cctacagcca gggcggcctg
      181 gtctcccggg cccacacgga gggcgaggtg ctgtccgccg agcacaccga acagggcacc
      241 ttgctgaagg cgcgggtggg gccggagctg gcggccgctc tgagggcctg cccccagccg
      301 tgacccgggc gggagggccg caggacggac cggccctccc ttccgggccc ggccggaccg
      361 gttgccgggg gcgcggcgac ttcactcacc cagatcagga ggactcctgc gtgtcgacag
      421 cgcaactagc tctgcatgac atcaccaagc gttaccagga ccacgtcgta ctcgaccgga
      481 tcggcttcac catcaagccg ggcgagaagg tcggtgtcat cggggacaac ggatccggca
      541 agtccacgct gatcaagctc atcgccgggc gggaacagcc ggacaacggt gcggtgacgg
      601 tggtcgcgcc cggtggcgtc ggctatctgg cccagacact ggagctgccg ctggaggcca
      661 cggtccagga cgccgtcgat ctggccctgg ccgacctgcg ggagctggag gagggcatgc
      721 gccggaccga ggccgagctg gccgaacggc cctaccaaac gggccaagac cccgaactcg
      781 ccggcctcct ggagagttac gccgcgctgg tggaccggta tcaggcccgc ggcggctacg
      841 aggccgactc ccgcgtggag atcgcgctgc acgggctcgg gctgcccggg ctggaacgcg
      901 gccggcggct gggcaccctg tccggcggcg agcgctcgcg cctcgccctg gcggcgacgc
      961 tggcctcgga acccgaactg ctgctgttgg acgagccgac caacgacctg gacgaccggg
     1021 ccgtggactg gctggaggaa cacctgcgca agcacaaagg caccgttgtc gccgttaccc
     1081 acgaccggct cttcctcgac cggctcacca ccacgatcct ggagatcgac tccggcaagg
     1141 tgatgcgcta cggcaacggc tacgagggct acctggcagc caaggcggcg gaacggcagc
     1201 gcaggctgct tgagtacgag cagtggcgcg ccgagctgga ccgcagccgc gacctgatcg
     1261 cgtccaacgt ggcgcgtctg gacgccatcc cacgcaagct gcccttcgcc gtcttcggcg
     1321 ccggccagtt ccggatgcgc gggcggggcc atggtgcgat ggtgcggatc cgcaacgcca
     1381 aggaacgcgt cgcgcggctg accgaaaacc cggtcgcgcc gccgcccgag ccgctcacct
     1441 tcaccgcgga gatcaccacc gaggccgcgc agtcccggga gacggtggcc gaactcaccg
     1501 gcgtccgggt cggcgaccgg ctcagcgtcg actccctgca cctcgggccc ggtgaacggc
     1561 tgctggtcac cggccccaac ggggcgggca agacgacgct gctgcgggtg ctctccgggg
     1621 agctggaacc cgacagcgga tccctgctgg tgtcgggccg ggtgggacac ctgaggcagg
     1681 aacagacacc atggcggccg ggtatgacgg tgcttcaggc gttcagcagc ggacgggccg
     1741 gtgacatcga cgagcacacc gaggcgctgc tctccctcgg gctgttcagc ccggacgacc
     1801 tccgccagcg tgtgcaggac ctgtcgtacg ggcagcggcg ccgcatcgag cttgcccggc
     1861 tggtgacgga gccggtcgac ctgctgctgc tggacgaacc caccaaccac ctctcgcccg
     1921 cgctcgtcga ggaactggag gaggcgctga ccggttatca gggcacggtc gtcgtcgtca
     1981 cccacgaccg gcgcatgcgg tcccgcttca acggcgccca tctgacgctg caggacgggc
     2041 gcgtcgccga gttcaccgcc gcctgatcgc cgaagcggta cgaggaggga cgggtgccag
     2101 gggcccgtcc ctccgcacgg tcagagacgg accggcagac tcttcagacg ccacgcaccc
     2161 gggaagggct gccgttccag ggcggacggc ggcacggcga gggcgaggct ggggaagcgg
     2221 tcgaagaggg tgtcgagggc gatcgcggtc tcctggtgtg ccagggcggc gcccaggcag
     2281 tagtgcgggc cgaagccgaa gccgacgtgt gcctcgtgcg gtgcgcggtg gtttccgggt
     2341 gatgtcgaac cgctcggggt cgggggaacc ggtccggatc gtgtccggcg gcg
//