From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for adenylosuccinate lyase
Date: 21 Jul 92 10:05:18 GMT
Distribution: bionet
Checksum: 30518     5

LOCUS       HUMASUCL     1692 bp ss-RNA             PRI       21-JUL-1992
DEFINITION  H.sapiens mRNA for adenylosuccinate lyase
ACCESSION   X65867
KEYWORDS    adenylosuccinate lyase.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1692)
  AUTHORS   Fon,E.A. and Rouleau,G.A.
  TITLE     Characterization of the human adenylosuccinate lyase gene
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: stage=fetal; *source: tissue=brain; *source:
            clone_library=lambda zapII; *source: clone=Z9.2; *source:
            chromosome=22;
            See also Stone R.L., Nature Genetics 1:59-63(1992)
            From EMBL    entry HSASUCL;  dated 11-JUN-1992.
FEATURES             Location/Qualifiers
     CDS             3..1457
                     /EC_number="4.3.2.2"
                     /note="ORF-1"
                     /product="adenylosuccinate lyase"
                     /codon_start=1
                     /translation="MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWL
                     WLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKA
                     AGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHF
                     QPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHK
                     VEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLK
                     EMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDS
                     ANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKA
                     GGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFT
                     GRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL"
     CDS             78..1457
                     /EC_number="4.3.2.2"
                     /note="ORF-2"
                     /product="adenylosuccinate lyase"
                     /codon_start=1
                     /translation="MCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNL
                     ENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNA
                     LDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQN
                     LKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTY
                     TRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRS
                     ERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNIS
                     EGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQE
                     GGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESV
                     MKVKAELCL"
BASE COUNT      449 a    390 c    422 g    431 t
ORIGIN
        1 ccatggcggc tggaggcgat catggttcgc ccgacagcta ccgctcacct cttgcctccc
       61 gctatgccag cccggagatg tgcttcgtgt ttagcgacag gtataaattc cggacatggc
      121 ggcagctgtg gctgtggctg gcggaggccg agcagacatt gggtttgcct atcacagatg
      181 aacaaatcca ggagatgaaa tcaaacctgg agaacataga cttcaagatg gcagctgagg
      241 aagagaaacg tttacgacat gatgtgatgg ctcacgtgca cacatttggc cactgctgtc
      301 caaaagctgc aggcattatt caccttggtg ctacttcttg ctatgttgga gacaatactg
      361 acttgattat tcttagaaat gcacttgacc tgcttttgcc aaagcttgcc agagtgatct
      421 ctcggcttgc cgactttgct aaggaacgag ccagtctacc cacattaggt ttcacacatt
      481 tccagcctgc acagctgacc acagttggga aacgttgctg tctttggatt caggatcttt
      541 gcatggatct ccagaacttg aagcgtgtcc gagatgacct gcgcttccgg ggagtaaagg
      601 gtaccactgg cactcaggcc agtttcctgc agctctttga gggagatgac cataaggtag
      661 agcagcttga caagatggtg acagaaaagg caggatttaa gagagctttc atcatcacag
      721 ggcagacata tacacgaaaa gtggatattg aagtactgtc tgtgctggct agcttggggg
      781 catcagtgca caagatttgc accgacatac gcctcctggc aaacctcaag gagatggagg
      841 aaccctttga aaaacagcag attggctcaa gtgcgatgcc atataagcgg aatcccatgc
      901 gttcagaacg ttgctgcagt cttgcccgcc acctgatgac ccttgtcatg gacccgctac
      961 agacagcatc tgtccagtgg tttgaacgca cactggatga tagtgccaac cgacggatct
     1021 gtttggccga ggcatttctt accgcagata ctatattgaa tacgctgcag aacatttctg
     1081 aaggattggt cgtgtacccc aaagtaattg aacggcgcat tcggcaagag ctgcctttca
     1141 tggccacaga gaacatcatc atggccatgg tcaaagctgg aggtagccgc caggattgcc
     1201 atgagaaaat cagagtgctt tctcagcagg cagcttctgt ggttaagcag gaagggggtg
     1261 acaatgacct catagagcgt atccaggttg atgcctactt cagtcccatt cactcccagt
     1321 tggatcattt actggatcct tcttctttca ctggtcgtgc ctcccagcag gtgcagagat
     1381 tcttagaaga ggaggtgtat cccctgttaa aaccatatga aagcgtgatg aaggtgaaag
     1441 cagaattatg tctgtagagt tggaagagaa ttaaacgaaa atcattgtta attgctgagg
     1501 catgaaaatt gtgttactat aacgccttat tttacctcga gaattgttac cttaaattag
     1561 tacagcactt tcttcttccc atggtgcttt cctgtttctc agtctcacat ttctcaacaa
     1621 ggcaaaaaca aagagcgttg aagttgactc tgctcttgca tagtaaatgt agttcatact
     1681 tgaaaaaaaa aa
//