From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus adenylyl cyclase type VI mRNA, complete cds.
Date: 31 Dec 92 01:47:33 GMT
Distribution: bionet
Checksum: 59833 9

LOCUS       RATADCYB     4131 bp ss-mRNA            ROD       18-DEC-1992
DEFINITION  Rattus norvegicus adenylyl cyclase type VI mRNA, complete cds.
ACCESSION   M96160
KEYWORDS    adenylate cyclase; adenylyl cyclase type VI.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) adult liver, kidney,
            heart cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 4131)
  AUTHORS   Premont,R.T.
  TITLE     Multiple mechanisms underlying desensitization of the liver
            adenylyl cyclase system. Structure and cAMP regulation of liver
            adenylyl cyclases
  JOURNAL   Thesis (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 4131)
  AUTHORS   Premont,R.T., Chen,J., Ma,H.-W., Ponnapalli,M. and Iyengar,R.
  TITLE     Two members of a new subfamily of hormone-stimulated adenylyl
            cyclases
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 9809-9813 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             14..3556
                     /EC_number="4.6.1.1"
                     /evidence="EXPERIMENTAL"
                     /citation=[2]
                     /citation=[1]
                     /product="adenylyl cyclase type VI"
                     /codon_start=1
                     /translation="MPLPVARSGSGRSSMSWFSGLLVPKVDERKTAWGERNGQKRPRQ
                     ATRARGFCAPRYMSCLKNVEPPSPTPAARTRCPWQDEAFIRRAGPGRGVELGLRSVAL
                     GFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRLAQVFQSKQFPSAKLERLYQRYFFQMN
                     QSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVALLTCASVLFVVLMVVCNRHSFRQD
                     SMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCPVFFVYITYTLLPIRMRAAVLSG
                     LGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETR
                     GYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSI
                     LFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPE
                     ARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWS
                     NDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQCIETFLILG
                     ASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKENR
                     GAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFG
                     AYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGSFFPNAL
                     QRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPSDVTA
                     CHLRQLNYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMTFV
                     LGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVIL
                     LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF
                     LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEI
                     ISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEH
                     SFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQ
                     VLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS"
BASE COUNT      835 a   1190 c   1182 g    924 t
ORIGIN      
        1 ggcggcacca agaatgcccc tgcccgtggc ccgatccggt tctgggcgca gcagcatgtc
       61 atggtttagc ggcctcctgg ttcccaaagt ggatgaacgg aaaacagcct ggggcgaacg
      121 caatggacag aagcgcccac gccaggcgac ccgagcccgt ggcttctgcg cgccccgcta
      181 catgagctgc ctcaagaatg tggagccacc cagccccact cctgcagctc gcactcggtg
      241 cccctggcag gatgaagcct tcatcaggag ggctggcccg ggaaggggtg tggagctggg
      301 gctgcggtca gtggccttgg gttttgatga cactgaggtg accacaccga tggggacagc
      361 tgaagtggca cccgacacat cgcctcgaag cggtccgtcc tgctggcacc ggctagcgca
      421 ggtgttccag tctaagcagt tcccgtccgc caagctggag cgtctgtacc agcggtactt
      481 cttccagatg aaccagagca gcctcacgct gctcatggcg gtgcttgtgc tcctcatggc
      541 tgtactgttg accttccacg ccgcgcctgc cctgcctcag cctgcttatg tggccctgct
      601 gacctgtgcc tccgtccttt ttgtggtact catggtagtg tgtaaccgac atagcttccg
      661 ccaggactcc atgtgggtag tgagctatgt ggttctgggc atcctagcag ccgtgcaagt
      721 cgggggtgcc ctggcagcca acccacgcag cccctcagca ggcctttggt gccccgtgtt
      781 cttcgtctac atcacctaca cacttcttcc cattcgtatg cgagcggccg tgctcagtgg
      841 cctgggtctt tccaccctgc atttgatttt ggcctggcat ctcaacaatg gtgacccctt
      901 cctttggaag cagctcggtg ctaacgtggt gctcttcctg tgcaccaatg ccatcggtgt
      961 ctgcacgcac taccccgctg aagtgtctca gcgccaagcc tttcaggaga cccgtggtta
     1021 catccaggcc cggctgcact tgcagcatga gaatcgacag caggaacggc tgctgctgtc
     1081 ggtgttgccc cagcatgttg ccatggaaat gaaagaggat atcaacacaa aaaaggaaga
     1141 catgatgttc cacaagattt acatccagaa gcatgacaat gtcagcatcc tgtttgccga
     1201 catcgagggc ttcaccagcc tggcctccca gtgcactgcc caggaactgg tcatgacctt
     1261 gaatgagctc tttgcccggt tcgacaagct ggctgcggag aatcactgtc tgaggatcaa
     1321 gatcttagga gactgttact actgtgtgtc ggggctgccg gaggcccggg cagaccatgc
     1381 ccactgctgt gtggagatgg gggtagacat gatcgaggcc atctcgctgg tgcgtgaggt
     1441 aacgggtgta aatgtgaaca tgcgcgtggg catccacagc gggcgtgtac actgcggtgt
     1501 ccttggtctg cggaaatggc agtttgatgt ctggtccaac gatgtgaccc tggccaacca
     1561 catggaggcg gggggccggg cgggccgcat ccacatcact cgggccacac tgcagtacct
     1621 gaacggggac tatgaggtgg agccaggccg tggcggtgag cgcaacgcgt acctcaagga
     1681 gcagtgcatt gagaccttcc tcatactagg agccagccag aaacggaaag aggagaaggc
     1741 catgctggtc aagctgcagc ggacgcgggc caactccatg gaaggactga tgccccgctg
     1801 ggttcctgac cgtgccttct cccggaccaa ggactctaag gcattccgac agatgggcat
     1861 cgatgactct agcaaagaga accggggtgc ccaagatgct ctgaaccctg aggatgaggt
     1921 ggacgagttt ctgggccgag ccatcgatgc ccgaagcatc gaccagctgc gtaaggacca
     1981 tgtgcgccgg ttcctgctca ccttccagag ggaggatctc gagaagaagt attcacggaa
     2041 agtagaccct cgtttcggag cctacgtcgc ctgtgccctc ctggttttct gcttcatctg
     2101 tttcatccag ttcctcgtat tcccacactc cgccctgata ctcgggattt atgccgggat
     2161 cttccttttg ctgctggtca ccgtgctcat ctgtgctgtg tgctcctgtg ggtctttctt
     2221 ccccaacgcc ctgcagcgcc tgtcccgcag tatcgtccgc tcacgggtgc acagcacggc
     2281 tgttggagtc ttctcggttc tgcttgtgtt catctctgcc attgccaaca tgttcacctg
     2341 cagtcacacc ccactgagga cctgtgcggc ccggatgctg aacttaacac cgtccgatgt
     2401 caccgcctgc cacctacgac agctcaatta ctctctggga ctggaagctc ccctgtgtga
     2461 gggcaccgca cccacctgca gcttccctga gtactttgtc gggagtgtgc tgctgagtct
     2521 cttggccagc tccgtcttcc tccacatcag cagcattggc aagctagtta tgacctttgt
     2581 cttggggttc atctacttgc ttctgctttt gctgggtccc ccagccacca tctttgacaa
     2641 ctatgatcta ctgcttagcg tccatggctt ggcttcctcc aatgagacct tcgatgggct
     2701 ggactgccca gccgtaggga gggtagcgct caaatacatg acccctgtga ttctcctcgt
     2761 gttcgccctg gcactgtatc tacacgcaca acaggtggaa tctaccgccc gcctggactt
     2821 cctgtggaaa ctgcaggcca caggggagaa ggaggagatg gaggagttgc aggcctacaa
     2881 ccggcggctg ctgcataaca tccttcccaa ggacgtggct gcccacttcc tggcccggga
     2941 gcgccgcaac gacgagctgt actaccaatc ctgcgagtgc gtggctgtca tgtttgcctc
     3001 catcgccaac ttctctgagt tctatgtgga actggaggcg aacaatgagg gcgtggagtg
     3061 cctgcgactg ctcaatgaga tcatcgcgga ctttgatgag atcatcagtg aggagaggtt
     3121 ccggcagctg gagaagatca agaccatcgg tagcacttac atggccgcct ccgggctaaa
     3181 tgccagcacc tatgaccagg tcggccgctc gcacatcacc gccctggcag actacgccat
     3241 gcggcttatg gagcaaatga aacacatcaa cgaacactct ttcaacaact tccagatgaa
     3301 gatcgggttg aacatgggtc cggttgtagc aggtgtcatt ggggcccgga agccacagta
     3361 tgacatctgg ggaaacacgg tgaatgtttc cagccgtatg gacagcacag gagttcctga
     3421 ccgaatacag gtgaccacgg atctctacca ggttctagct gccaagggct accaactgga
     3481 gtgtcgaggg gtggtcaagg tgaagggaaa gggggagatg accacctact tcctcaatgg
     3541 gggccccagc agttagcaga gcgcacgagt ggaaattcaa ccaaagggac caaggtgggc
     3601 actgagtgga cttttctgct cactggatgg agctgtggca gggggctctg agccttcagg
     3661 tcttgctgac agcaaaaggg aacaccccag caggctgtgc ttggaccata tccgtctgcc
     3721 ttcagagcag caaaggaagg gacgccgaga ggattattat ccaagtgact ttcttaatca
     3781 gagtaaggct gtttgctttt ttttcccccc ctttggacgc agctgagagc agagcctcct
     3841 gtttgagagt aaaatggcaa cttactctgc ctactgtttc cctgtctggg cgacaggctc
     3901 agggctggga cctttctttc cctatttttc ctgggactat ttttgtacaa gagtggggca
     3961 ggcatgagga atgcttgcct tcactggcct gtgtcagcag catttgtctt gggcactccc
     4021 agtaccagcc aagtctcctt cctagcacaa caaggcagag gaaggaggtg ctgtgggacc
     4081 tagctctgac cagatttcag gggaatgttt ccatttgcca aatcctagtc c
//