From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Cryprococcus neoformans phosphoribosyl anthranilate isomerase
Date: 28 Jan 93 05:46:42 GMT
Distribution: bionet
Checksum: 38276 4

LOCUS       CPCTRP1      1708 bp ds-DNA             PLN       27-JAN-1993
DEFINITION  Cryprococcus neoformans phosphoribosyl anthranilate isomerase
            (TRP1) gene, complete cds.
ACCESSION   M74901
KEYWORDS    phosphoribosyl anthranilate isomerase.
SOURCE      Cryptococcus neoformans alpha DNA.
  ORGANISM  Cryptococcus neoformans
            Eukaryota; Fungi; Eumycota; Basidiomycotina; Filobasidiales.
REFERENCE   1  (bases 1 to 1708)
  AUTHORS   Perfect,J.R., Rude,T.H., Penning,L.M. and Johnston,S.A.
  TITLE     Cloning of the Cryptococcus neoformans TRP 1 gene by expression in
            Saccharomyces cerevisiae
  JOURNAL   Gene 122, 213-217 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             421..1359
                     /gene="TRP1"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
                     /note="Functionally this gene complements the TRP1
                     auxotroph of S.cerevisiae and has 39% identity and 62%
                     similarity to S.cerevisiae TRP1"
                     /product="phosphoribosyl anthranilate isomerase"
                     /codon_start=1
                     /translation="MSTTSRVNAALNGRDVVLCALSGISSHEDVEKYVKEGVKGVLVG
                     EALMRASDTKAFLRSLIGLPPLEVVSKPRPLVKICGIRSTNDAKLAINAGADLLGVIL
                     VPGTKRCISTSTAREISALVQSARSQSSSKPLEPSLSSPWFTSQSALLSSRRKPLLVG
                     VFQNQSLSDILSAVDEIGLDLVQLHGDEPQAWAKFIPVPVVKVFRVSPEGIVRGGEIR
                     RPGLNQAILLDAGGASGGGGEGKAFPWEHAKRLIQSGEVGSEGHVPLPVILAGGLTPE
                     NVGQALNRLVKAFGVWMSAVGSKEREGRSRRRLRRS"
BASE COUNT      378 a    451 c    411 g    468 t
ORIGIN      
        1 ttccaagggc gtaatgctcc tacgcttctg ctcctcagaa gcactaagta tgctcttgcc
       61 ggtgcttccg tcatctcggt actcacataa cctacgtggt tcaagggcag cttgcttgac
      121 atgctcgctg tacgcaacgc tgttgacagt cttcccaacc gtcctgccat cttgcggaag
      181 gactttgttt tgtccaaata catgattgat gaggctagat tgtatggtgc cgatactgtg
      241 cttctcattg tcgccatgct cgagcctcag caacttaagg aattgtacga ttactctgtc
      301 tctcttggca tggaacccct cgtcgaggtc aacaacccta ccgagctctc actcgcactt
      361 gaaattggat ccaaggtcat tggtgtgaat aaccgtaatc tacacgactt taacgttgac
      421 atgtccacca cttctcgagt caacgctgct ctcaacggac gggacgttgt tctctgcgct
      481 ttgagcggta tttcgagcca cgaggatgtt gagaaatatg tcaaggaagg tgtcaagggt
      541 gtgcttgttg gtgaggcttt gatgcgagcg agcgacacca aggctttcct ccggtcactt
      601 attggcttac cgcctctaga agtcgtttct aagcccagac cgctcgtcaa gatttgcggt
      661 atccgttcta caaacgacgc taagcttgca atcaatgccg gtgccgatct cctcggtgta
      721 atccttgtcc ccggtacaaa acgttgcata tctacttcta ccgcccgcga aatttccgct
      781 cttgtccaat ccgcccgatc tcaatcttct tccaagccat tagaaccttc tctttcctct
      841 ccttggttta ccagccaatc cgccctcctc tcatcccggc gaaaacccct tctagttggt
      901 gtcttccaaa atcagtccct ctccgacatc ctgtcagccg tcgacgagat tggcctcgac
      961 cttgttcagt tacacggtga tgaaccccaa gcctgggcca agttcatccc cgtgcctgtg
     1021 gtcaaggtgt tccgggtttc acccgaagga atagttagag gtggtgagat taggcgacca
     1081 ggtttgaacc aagcaatttt gctcgacgcg ggtggtgcgt ctggcggtgg cggggaagga
     1141 aaagccttcc catgggaaca tgccaagcgg ctcatccaat ctggcgaggt gggatctgaa
     1201 ggtcatgtgc ctctccctgt catcctcgct ggtgggttga cgcctgagaa tgtgggccag
     1261 gcattgaaca ggctggtgaa ggcgtttggt gtgtggatgt cagcagtggg gtcgaaggag
     1321 agggagggaa ggtcaaggag aaggttgagg cgttcgtgaa ggcggtaagg ggttaatttt
     1381 ccttagaggg tgtatatata catattagag aagtgataca attttagcac actgcgaatc
     1441 cgagacagac atcgtgtcaa tcatcttttt tgacattata tgcccattaa tctatctaca
     1501 gacaacaata ccatccttcc caccctcagc aacgccgttg aatcctcagg atcttcatgg
     1561 ctccttgtct ctgaaaccag gaagctagtt tctacatctc ttctccatat cttttcccgc
     1621 cttagcgttt ccaattccac atgttcggat gaataaggct tttcaccatt tctcttctgt
     1681 cgcaaaagga tttcaaaaga acaagctt
//