From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.norvegicus GHF1 gene, exon 2B and alternative spliced 2A
Date: 24 Jul 92 10:09:30 GMT
Distribution: bionet
Checksum: 58363     6

LOCUS       RATGHF12     3286 bp ds-DNA             ROD       24-JUL-1992
DEFINITION  R.norvegicus GHF1 gene, exon 2B and alternative spliced 2A
ACCESSION   X65365
KEYWORDS    GHF-1 gene; GHF-2 gene; POU-domain protein; pit-1 gene;
            pituitary specific transcription factor.
SOURCE      Rattus norvegicus DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Theill,L.E.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1219 to 1388)
  AUTHORS   Theill,L.E., Hattori,K., Lazzaro,D., Castrillo,J.L. and Karin,M.
  TITLE     Differential splicing of the GHF1 primary transcripts gives rise to
            two functionally distinct homeodomain proteins
  JOURNAL   EMBO J. 11, 2261-2269 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=adult; *source: tissue=pituitary tumour; *source:
            chromosome=16; *source: is_germline=Y;
            See also X65364-8, X53660 & Bodner M. et al, Cell 55:505-518(1988)
            From EMBL    entry RNGHF12;  dated 15-JUN-1992.
FEATURES             Location/Qualifiers
     intron          <1..1307
                     /number=1
                     /note="1A"
     intron          <1..1228
                     /number=1
                     /note="1B"
     exon            1229..1378
                     /number=2
                     /usedin=X65364:ghf2_cds
                     /usedin=X65364:ghf2_mrna
                     /note="2B"
     exon            1308..1378
                     /number=2
                     /usedin=X65364:ghf1_cds
                     /usedin=X65364:ghf1_mrna
                     /note="2A"
     intron          1379..>3286
                     /number=2
BASE COUNT      920 a    519 c    520 g    951 t    376 others
ORIGIN
        1 gaattcaata aatacaaaac agtctacaaa acttccttta aatgattttt aaataattta
       61 taatttccta taaaatcata gctattaaca tatctaatta agtaaggaat tatagttatt
      121 ttaatgaaag cccttgggta ttaaatgtgt ttaagattca ttgaattttg gaaatgaatg
      181 gtgaaattgt tctgtgttac cattacatgg taaaattatt tcatgttgtt cgatatgggt
      241 tacaaactgg aaatttatgc agatatttac aaataatatt atgtatattt agacaaaata
      301 tatttgttcc atgaaaaggc atgccattaa cctctacacc atttgttaat attctcaaat
      361 actcctagtc atgtactctt atgctattta ttcaaaaaca tttgttatgc ttattataat
      421 aacctaccta taatattaat gtactatact acattatatt attatattta gggttagaga
      481 gaaaagtgag taagcaagtc cacagtgaaa ctttttctgg tggatgtttt ggtgaaaaac
      541 cttgttgaaa tgtgtttaaa gcttcctaca cattttataa ttcatatctt attaaatgca
      601 cactaatttt aggaattatt aacgagatta tgaggttcag caataaagaa aagttttgga
      661 ctggctatca attgtgagca tacagaacat ctacaagcca tggtttcaat gtcaacatta
      721 gtgcagtaga cactttcaca gggtcttcgt gaaaccctga aaaccgcagt ccttttagga
      781 ttgtatttaa acgagaagat atttacttat tatctcttta gtagacgaag ttgtaaagaa
      841 aatnagcaga tttatctgct atgacaattc aagagcgaat tacatattca ctttttcaga
      901 gacaagctcc tgattatact gtgatacata tgatgtccag aggctttcca atgactgtgg
      961 tataatatct accctatctg gaatccacag gaatattaca gtccaccatc ctctcatttc
     1021 tcctcatgag atacttatat ccacaacata ggtcacactg caatctagtt tgatgactta
     1081 ggatctcatc acttaagaca acccttggtt gattttattt gcttattcag aaactctcag
     1141 tgaagaaaat acaattttaa aatcatgtaa atgtgtaatc ttgaaatgag atagaatgtg
     1201 tcttgaaccc tcatactttt cttaccagtc ccgtctattt tgtctttgat ccaaacacct
     1261 aaatgtttgc acacatattt ctcgatgaca acgatgggaa atacagcgac aggacttcat
     1321 tattctgtgc cttcctgtca ttatggaaac cagccatcca cctacggagt gatggcaggt
     1381 aagaaacatt acctttacgt gtagtatcac cgggggaaaa cagtgttgag tttcccgggc
     1441 cagagagagt ggagggaaga ctgtgacgcg aaattctgat cttacagctt gaaagttggt
     1501 ggtagatttg tcactttctg gagtgtctga tgttcaataa agcatgaggc tctaagaaat
     1561 atcatgaccc aagatgaccc tgttctagag acttctccac tcctgctcct gaactttgca
     1621 cgagctttat atggttttgc tgttattttt tgttcttcct ctttctttct tttttaaatt
     1681 ttaattatgt taaactgcta gttaccactt gttactgccc ttatgggatt ccctgcagca
     1741 attctatact aactagctag actnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnntttc
     1861 aggagaagtg aagccatacc tctttcaagc ataattctgg cacaccggta ttgtctgtgt
     1921 acacacattc gcagaacggc tgtctacaat tgggaccacc tgcccttcga gttccactca
     1981 tgcacaaatc agtacttaat ctcaggcatg gccaaataca gcattttact gggttaaatg
     2041 aacatggatt gctgttcaca gagttttact cgttagcttg tgctcaagga gatattttag
     2101 tggtctgtat ttgttgttac ggcagcaaaa taactctcat cagagagaaa tcaagaccaa
     2161 gacagaagat agtgtggaaa gtgaaacgga gacagacaga cagacagtgg agattttgga
     2221 gaaaagggtc aaatatgcag gcaatctttg gagctgactt atgtttgtcc tccaagtaaa
     2281 caattacaca cagagaaaca tagaggtgtg cttagaattt tgaaataaaa acggaacaaa
     2341 taatttaatt cattaatcta gannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt ctagagagtt
     2521 tatagttacc ttcagagtcc tataatgtat tccaaattag taatggggcc agggtcccat
     2581 taagacacag ctgacagcac tccacatacc ttttccattt cccgacatcc tgatcttaat
     2641 atagtcaaat agaaaggacc tgagaaggac tctaccaaag tctggtttag tgacatcata
     2701 aacacaattg taataccaag atttagaggc atcattgtag ccttcaaatt aaattatatt
     2761 ttgtcactaa aatgaaacct caccatggtg cagagagact atatttgaat atttctagga
     2821 gagatgtcat taaaatatta tncgctttat aatttgtcag catgtctggg tcttgacata
     2881 tattccactt aacatgctct tcgtggcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntttctgaaa ctgtcagcca
     3061 ctccctcaaa atctacagaa gcatctatgg gcaggctagg tatcttacag tctgagggga
     3121 agctacccaa atactgtttc aaagggcgta gagttgtttt aatatggcta ttatattacc
     3181 tgatgcattc attttagggt tttgttaagt taactcactg gaagggacaa gctacagaga
     3241 tttttttcca ggttgatgtg gaagatttaa atcctgagat gaattc
//