From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human hepatic leukemia factor (HLF) mRNA, complete cds.
Date: 18 Aug 92 10:02:30 GMT
Distribution: bionet
Checksum: 56959     7

LOCUS       HUMHLF       3865 bp ss-mRNA            PRI       18-AUG-1992
DEFINITION  Human hepatic leukemia factor (HLF) mRNA, complete cds.
ACCESSION   M95585
KEYWORDS    hepatic leukemia factor.
SOURCE      Homo sapiens hepatoma cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3865)
  AUTHORS   Inaba,T., Roberts,W.M., Shapiro,L.H., Jolly,K.W., Raimondi,S.C.,
            Smith,S.D. and Look,A.T.
  TITLE     Fusion of the leucine zipper gene HLF to the E2A gene in human
            acute B-lineage leukemia
  JOURNAL   Science 257, 531-534 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     5'UTR           <1..322
                     /gene="HLF"
     mRNA            <1..3865
                     /gene="HLF"
                     /note="putative"
     CDS             323..1210
                     /function="Unknown"
                     /product="hepatic leukemia factor"
                     /gene="HLF"
                     /evidence=EXPERIMENTAL
                     /codon_start=1
                     /translation="MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDK
                     DKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPS
                     QHDHSPHPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNT
                     PSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVF
                     IPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRK
                     ELGKCKNILAKYEARHGPL"
     3'UTR           1208..3865
                     /gene="HLF"
                     /partial
     polyA_signal    3842..3847
                     /gene="HLF"
                     /note="putative"
BASE COUNT     1072 a    821 c    805 g   1167 t
ORIGIN
        1 tttttcaatt ttgaacattt tgcaaaacga ggggttcgag gcaggtgaga gcatcctgca
       61 cgtcgccggg gagcccgcgg gcacttggcg cgctctcctg ggaccgtctg cactggaaac
      121 ccgaaagttt ttttttaata tatattttta tgcagatgta tttataaaga tataagtaat
      181 ttttttcttc ccttttctcc accgccttga gagcgagtac ttttggcaaa ggacggagga
      241 aaagctcagc aacattttag ggggcggttg tttctttctt tcttatttct tttttaaggg
      301 gaaaaaattt gagtgcatcg cgatggagaa aatgtcccga ccgctccccc tgaatcccac
      361 ctttatcccg cctccctacg gcgtgctcag gtccctgctg gagaacccgc tgaagctccc
      421 ccttcaccac gaagacgcat ttagtaaaga taaagacaaa gaaaagaagc tggatgatga
      481 gagtaacagc ccgacggtcc cccagtcggc attcctgggg cctaccttat gggacaaaac
      541 ccttccctat gacggagata ctttccagtt ggaatacatg gacctggagg agtttttgtc
      601 agaaaatggc attcccccca gcccatctca gcatgaccac agccctcacc ctcctgggct
      661 gcagccagct tcctcggctg ccccctcggt catggacctc agcagccggg cctctgcacc
      721 ccttcaccct ggcatcccat ctccgaactg tatgcagagc cccatcagac caggtcagct
      781 gttgccagca aaccgcaata caccaagtcc cattgatcct gacaccatcc aggtcccagt
      841 gggttatgag ccagacccag cagatcttgc cctttccagc atccctggcc aggaaatgtt
      901 tgaccctcgc aaacgcaagt tctctgagga agaactgaag ccacagccca tgatcaagaa
      961 agctcgcaaa gtcttcatcc ctgatgacct gaaggatgac aagtactggg caaggcgcag
     1021 aaagaacaac atggcagcca agcgctcccg cgacgcccgg aggctgaaag agaaccagat
     1081 cgccatccgg gcctcgttcc tggagaagga gaactcggcc ctccgccagg aggtggctga
     1141 cttgaggaag gagctgggca aatgcaagaa catacttgcc aagtatgagg ccaggcacgg
     1201 gcccctgtag gatggcattt ttgcaggctg gctttggaat agatggacag tttgtttcct
     1261 gtctgatagc accacacgca aaccaacctt tctgacatca gcactttacc agaggcataa
     1321 acacaactga ctcccatttt ggtgtgcatc tgtgtgtgtg tgcgtgtata tgtgcttgtg
     1381 ctcatgtgtg tggtcagcgg tatgtgcgtg tgcgtgttcc tttgctcttg ccattttaag
     1441 gtagccctct catcgtcttt tagttccaac aaagaaaggt gccatgtctt tactagactg
     1501 aggagccctc tcgcgggtct cccatcccct ccctccttca ctcctgcctc ctcagctttg
     1561 cttcatgttc gagcttacct actcttccag gactctctgc ttggattcac taaaaagggc
     1621 cctggtaaaa tagtggatct cagtttttaa gagtacaagc tcttgtttct gtttagtccg
     1681 taagttacca tgctaatgag gtgcacacaa taacttagca ctactccgca gctctagtcc
     1741 tttataagtt gctttcctct tactttcagt tttggtgata atcgtcttca aattaaagtg
     1801 ctgtttagat ttattagatc ccatatttac ttactgctat ctactaagtt tccttttaat
     1861 tctaccaacc ccagataagt aagagtacta ttaatagaac acagagtgtg tttttgcact
     1921 gtctgtacct aaagcaataa tcctattgta cgctagagca tgctgcctga gtattactag
     1981 tggacgtagg atattttccc tacctaagaa tttcactgtc ttttaaaaaa caaaaagtaa
     2041 agtaatgcat ttgagcatgg ccagactatt ccctaggaca aggaagcaga gggaaatggg
     2101 aggtctaagg atgaggggtt aatttatcag tacatgagcc aaaaactgcg tcttggatta
     2161 gcctttgaca ttgatgtgtt cggttttgtt gttccccttc cctcacaccc tgcctcgccc
     2221 ccacttttct agttaacttt ttccatatcc ctcttgacat tcaaaacagt tacttaagat
     2281 tcagttttcc cactttttgg taatatatat atttttgtga attatacttt gttgttttta
     2341 aaaagaaaat cagttgatta agttaataag ttgatgtttt ctaaggccct ttttcctagt
     2401 ggtgtcattt ttgaatgcct cataaattaa tgattctgaa gcttatgttt cttattctct
     2461 gtttgctttt gaacgtatgt gctcttataa agtggacttc tgaaaaatga atgtaaaaga
     2521 cactggtgta tctcagaagg ggatggtgtt gtcacaaact gtggttaatc caatcaattt
     2581 aaatgtttac tatagaccaa aaggagagat tattaaatcg tttaatgttt atacagagta
     2641 attataggaa gttctttttt gtacagtatt tttcagatat aaatactgac aatgtatttt
     2701 ggaagacata tattatatat agaaaagagg agaggaaaac tattccatgt tttaaaatta
     2761 tatagcaaag atatatattc accaatgttg tacagagaag aagtgcttgg gggtttttga
     2821 agtctttaat attttaagcc ctatcactga cacatcagca tgttttctgc tttaaattaa
     2881 aattttatga cagtatcgag gcttgtgatg acgaatcctg ctctaaaata cacaaggagc
     2941 tttcttgttt cttattaggc ctcagaaaga agtcagttaa cgtcacccaa aagcacaaaa
     3001 tggattttag tcaaatattt attggatgat acagtgtttt ttaggaaaag catctgccac
     3061 aaaaatgttc acttcgaaat tctgagttcc tggaatggca cgttgctgcc agtgccccag
     3121 acagttcttt tctaccctgc gggcccgcac gttttatgag gttgatatcg gtgctatgtg
     3181 tttggtttat aatttgatag atgtttgact ttaaagatga ttgttctttt gtttcattaa
     3241 gttgtaaaat gtcaagaaat tctgctgtta cgacaaagaa acattttacg ctagattaaa
     3301 atatcctttc atcaatggga ttttctagtt tcctgccttc agagtatcta atcctttaat
     3361 gatctggtgg tctcctcgtc aatccatcag caatgcttct ctcatagtgt catagacttg
     3421 ggaaacccaa ccagtaggat atttctacaa ggtgttcatt ttgtcacaag ctgtagataa
     3481 cagcaagaga tgggggtgta ttggaattgc aatacattgt tcaggtgaat aataaaatca
     3541 aaaacttttg caatcttaag cagagataaa taaaagatag caatatgaga cacaggtgga
     3601 cgtagagttg gcctttttac aggcaaagag gcgaattgta gaattgttag atggcaatag
     3661 tcattaaaaa catagaaaaa tgatgtcttt aagtggagaa ttgtggaagg attgtaacat
     3721 ggaccatcca aatttatggc cgtatcaaat ggtagctgaa aaaactatat ttgagcactg
     3781 gtctctcttg gaattagatg tttatatcaa atgagcatct caaatgtttt ctgcagaaaa
     3841 aaataaaaag attctaataa aaaaa
//