From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA MBP-2 for MHC binding protein 2
Date: 31 Dec 92 01:30:33 GMT
Distribution: bionet
Checksum: 48203 17

LOCUS       HUMMBPROT2   9175 bp ss-RNA             PRI       16-DEC-1992
DEFINITION  H.sapiens mRNA MBP-2 for MHC binding protein 2
ACCESSION   X65644
KEYWORDS    MHC binding protein 2.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 9175)
  AUTHORS   van 't Veer,L.J., Lutz,P.M., Isselbacher,K.J. and Bernards,R.
  TITLE     Structure and expression of major histocompatibility
            complex-binding protein 2, a 275-kDa zinc finger protein that binds
            to an enhancer of major histocompatibility complex class I genes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 8971-8975 (1992)
  STANDARD  full automatic
COMMENT     *source: cell_line=adenovirus transformed retinal cells, Nalm-6
            pre-B cell *source: line, HOS osteosarcoma e; *source: chromosome=
            18;
               From EMBL    entry SSMBPROT2;  dated 13-NOV-1992.
FEATURES             Location/Qualifiers
     polyA_site      9154
     CDS             16..7518
                     /product="MBP-2 (MHC Binding Protein-2)"
                     /codon_start=1
                     /translation="MLFLNLATAHQEIEYISPPLEHGSNQALRSTALETLHESALLSG
                     ELALKTLCNKMDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQP
                     QIEPEQIGNTASAQLFGSGKLASPSEVVQQVAEKQYPPHRPSPYSCQHSLSFPQHSLP
                     QGVMHSTKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHSGGYPRKKISSLNPAYSQ
                     YSQKSIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPC
                     GFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTD
                     TDEESSLFAEASDKMSPGPPIPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLP
                     NESSQYIGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGST
                     DSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKG
                     IMEPLPHVNTRLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSI
                     RNEGKLYPANFQGSNPVLLEAPVDSSPLIRSNSVPTSSATNLTIPPSLRGSHSFDERM
                     TGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSLKEKKL
                     SPGDRVGYDYDVCRKPYKKWEDSETPKQNYRDISCLSSLKHGGEYFMDPVVPLQGVPS
                     MFGTTCENRKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQMQEGVRSGFAM
                     AGHENLSHGHTERFDPCRPQLQPGSPSLVSEESPSAIDSDKMSDLGGRKPPGNVISVI
                     QHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPVSPEWAPPGDGAESG
                     GKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAQSKEPEKPVEEF
                     QWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHS
                     SSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQ
                     MPCPHPAEVPEVRSKSFDYGNLSHAPVSGAAASTVSPSRERKKCFLVRQASFSGSPEI
                     SQGEVGMDQSVKQEQLEHLHAGLRSGWHHGPPAVLPPLQQEDPGKQVAGPCPPLSSGP
                     LHLAQPQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQETIPFSPIQNALFQF
                     QYPTVCMVHLPAQQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGK
                     KPAEYAHTKEQTYPCYSGASGLHPKNLLPKFPSDQSSKSTETPSEQVLQEDFASANAG
                     SLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNA
                     AMQGIGFNIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPLCLPSTSDSVATLGGSKR
                     MLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQ
                     GCASEPKDGLQSGSSSFSSLSPSSSQDYPSVSPSSREPFPPSKEMLSGSRAPLPGQKS
                     SGPSESKESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASA
                     PSGNVADSTLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYAS
                     WCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFTQM
                     KPDASFLFGSKLERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDY
                     VYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHM
                     KSKAHMKKCLELGVSMTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESD
                     GEDGDDNDDDDEDEDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHGVPSDSS
                     LGHSSLISYLVTLPSIRVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPS
                     CMDEECMLPSEPSSSPRDFSPSSHHSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSP
                     RRDLSPMRHLSPTKEAALRREMSQRDVSPRRHLSPRRPVSPGKDITARRDLSPRRERR
                     YMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSLYGDQEGAY
                     EHPGSSLFPEGPNDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSMPPALSSLHPSPT
                     LPLPMEGFEEKKGASGESFSKDPYVLSKQHEKRGPHALQSSGPPSTPSSPRLLMKQST
                     SEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGPDQPARVQEPHQNPLGSAHVS
                     IRHFSRPEPGQPCTSATHPDLHDGEKDNFGTSQTPLAHSTFYSKSCVDDKQLDFHSSK
                     ELSSSTEESKDPSSEKSQLH"
BASE COUNT     2635 a   2168 c   2115 g   2257 t
ORIGIN      
        1 tatgtttagt cccatatgct cttcctgaat cttgccactg cccatcaaga gatagaatac
       61 atttcccctc cccttgaaca tggaagcaac caagctttaa gaagcacagc tttggagaca
      121 ctccatgagt ctgcactgct ttcaggggaa ctagcactta agaccttgtg taacaaaatg
      181 gacactgggg acacagctct aggacaaaaa gctacctcaa ggtctggaga aactgataaa
      241 gcatcaggta gatggagaca ggaacaatca gctgttatta agatgagcac ttttggcagt
      301 catgaaggac agcggcaacc acaaatagag cctgagcaaa tcggaaacac agcatcagca
      361 caactgtttg gttctgggaa actggcctcc cctagtgaag tggtgcagca agtcgcagag
      421 aagcaatatc caccgcatcg tccgagtcct tactcatgcc aacactcact ctctttccct
      481 cagcactcat tgccacaggg ggtcatgcac agcaccaagc cacatcagag cctcgaaggt
      541 cctccgtggc ttttccctgg ccctttgcca tccgttgcct ctgaggactt atttcctttt
      601 cctatacatg gccacagtgg tggttatcct agaaaaaaga tttcaagtct gaaccctgct
      661 tatagccaat actcccagaa aagtattgaa caggcagaag aggctcacaa gaaagagcac
      721 aaacccaaaa agcctggcaa gtacatttgc ccttactgca gcagagcgtg tgccaaacct
      781 agtgtactga aaaaacacat caggtcccat actggggagc ggccatatcc atgtatacct
      841 tgtggtttct ctttcaagac aaagagcaat ttgtacaagc acaggaagtc acatgcccat
      901 gcaattaagg caggattagt acctttcaca gagtcagctg tatctaaatt ggacctagag
      961 gctggtttta ttgatgtaga agcagaaata cattcagatg gtgaacagag tacagacaca
     1021 gatgaggaga gttctttatt tgccgaggct tctgacaaaa tgagtcctgg tccacccatc
     1081 ccactggaca ttgccagcag aggcggctat catgggtcat tggaagaatc attgggaggt
     1141 ccaatgaagg tgccgatttt gattatccct aaaagtggga ttcctctccc taatgaaagc
     1201 tctcagtata ttggccctga tatgctacca aatccatctt taaatactaa ggctgatgat
     1261 tcgcacacag tcaaacagaa acttgcacta agactgtcag agaaaaaagg acaagattct
     1321 gagccatcgc tcaaccttct gagcccgcac agtaaaggaa gcactgattc tggttacttt
     1381 tctcgctcag aaagtgctga gcagcaaata agccctccca acacaaatgc aaagtcttat
     1441 gaagaaatca tctttggaaa atactgtcgg cttagtccga gaaatgcact cagtgttaca
     1501 accacaagtc aggagcgtgc cgcaatgggt aggaagggca taatggaacc attacctcac
     1561 gttaacacca ggttagatgt caagatgttt gaagatcctg tttcacagct gatcccaagc
     1621 aagggagatg tcgaccccag tcaaacgagc atgctgaaat ccactaagtt caacagtgag
     1681 tccagacaac cccagattat tccatcatct atcaggaacg aaggaaaact ttatccagca
     1741 aacttccaag gcagcaaccc ggttctctta gaagctcctg tagactcttc accccttatt
     1801 agaagcaact cagtgccaac ttcttcagca actaatctaa ctattcctcc ttctttgaga
     1861 ggaagtcact catttgatga aaggatgact ggttccgacg atgtattcta tccagggacc
     1921 gtgggcatac cccctcagcg catgctaaga agacaagcgg catttgagct gccttcggta
     1981 caggagggcc acgtggaagt cgagcaccat ggcaggatgt tgaagggtat cagcagttca
     2041 tccctgaagg aaaagaaatt gtctcctggg gacagggttg ggtatgacta tgatgtctgt
     2101 cggaaaccct ataagaagtg ggaggactct gaaacaccaa agcaaaacta cagggacatt
     2161 tcctgcttga gttctttaaa gcatggtgga gaatatttca tggatcccgt ggtgccattg
     2221 cagggagtac caagcatgtt tggaactacc tgtgaaaaca ggaaacgccg gaaagagaag
     2281 agcgtagggg atgaagagga cacgcccatg atctgcagca gcattgtaag cactcctgtg
     2341 ggcatcatgg cttccgatta tgaccccaaa ctgcagatgc aggaaggagt caggagtgga
     2401 tttgccatgg ctggacacga aaacctttct catggtcaca cggaacgctt tgacccatgt
     2461 cggccccaac tgcagcctgg aagtccatct cttgtgtcag aggagtcacc ttcagccatt
     2521 gattcagaca agatgtcaga cctagggggc aggaaacctc ctggaaatgt gatttctgtg
     2581 attcagcaca ccaactcact gagccgaccc aattcatttg aaaggtctga gtcagccgaa
     2641 cttgtggctt gcacacagga taaagcccct tccccttcag agacttgtga cagtgagatt
     2701 tcagaagccc cagtgagtcc tgagtgggct ccacctgggg atggtgcaga aagtgggggg
     2761 aaaccctctc catctcagca ggtgcagcag cagtcctatc acacacagcc caggctagtt
     2821 cggcaacaca acatccaggt tcctgagatt cgagtgaccg aggagcctga taaacctgag
     2881 aaggagaagg aagcccagag caaagagcca gagaagcctg tggaagaatt tcagtggccc
     2941 cagagaagtg agaccctttc ccagctcccc gcggagaagt tgcctcccaa aaagaagcgt
     3001 ctgcgacttg cagatatgga gcactcctca ggggagtcca gctttgaatc cacaggcaca
     3061 ggcctctccc gcagccccag ccaagaaagc aacttgtccc acagctccag tttctccatg
     3121 tcttttgaaa gagaagaaac cagtaagctt tctgcacttc ctaagcagga tgagtttggg
     3181 aagcattcag agtttctgac tgtccctgct ggttcatact cattgtctgt cccaggccat
     3241 caccaccaga aagagatgcg acgctgctca tcagagcaga tgccttgtcc tcacccagcg
     3301 gaagtcccag aagttcggag caaatcattt gattatggga atctgtccca tgctcctgtg
     3361 tcgggagcag cagcctccac ggtatcaccg tccagggaga ggaagaaatg ctttctggtg
     3421 cggcaagctt ccttcagtgg ctccccagaa atctcccagg gcgaggttgg catggatcag
     3481 agcgtgaagc aagagcagct ggagcacctg catgctggcc tccggtccgg gtggcaccat
     3541 ggcccgcctg ctgtgctgcc tcctcttcag caagaggacc cagggaagca ggtggcgggt
     3601 ccttgtcccc cgctgagctc ggggccactg cacctggccc agccacagat catgcacatg
     3661 gacagtcagg aatctttgag aaatcccttg atccaaccaa catcctatat gacaagcaag
     3721 cacttacctg aacagccaca cttatttcca catcaagaga caattccatt ttctccaatc
     3781 cagaatgcct tgtttcagtt tcagtatcct acagtttgta tggttcattt accagctcag
     3841 cagcctccct ggtggcaggc acatttccca catccctttg ctcagcaccc tcagaagagc
     3901 tatggcaagc cctcttttca gacagaaatc cattcgagct atcccttaga gcatgtggca
     3961 gagcacactg gaaagaaacc tgctgagtat gcacacacga aagagcagac ctacccatgt
     4021 tattcaggag catcagggct acacccaaag aaccttcttc caaagtttcc atcagaccag
     4081 agcagtaagt caactgaaac gccctctgag caggttcttc aagaagattt tgcctcggca
     4141 aatgctgggt ctttgcagtc cctcccagga acagtggttc ctgttcggat ccagacgcac
     4201 gtaccatcct atggaagtgt catgtacaca agcatttctc agatacttgg gcagaatagc
     4261 cctgccattg tcatatgcaa agtcgatgag aatatgaccc aaaggacact ggtcaccaac
     4321 gcagccatgc aagggatagg attcaacatt gcccaggtgc tggggcagca tgcgggcttg
     4381 gagaagtacc ccatttggaa agcacctcag actttgcccc tcggcttaga atcctccatc
     4441 cccttgtgtt taccttccac ctctgacagc gtggccaccc tgggaggtag caagcgaatg
     4501 ctttctccag ccagtagctt ggagctcttc atggaaacca agcagcagaa aagggtcaaa
     4561 gaagaaaaga tgtacggaca gattgtggag gagcttagtg ctgtggagct gaccaactca
     4621 gacatcaaaa aggacctctc ccgcccccag aaaccccagc tggttcgaca aggatgtgct
     4681 tctgagccaa aagatggctt gcagtcaggg tcatcttcct tctcctcgct gtcgccctcc
     4741 tcatctcaag actatccttc tgttagcccg tcttccaggg agccattccc gcccagcaag
     4801 gagatgcttt ccggttcccg ggcaccactt ccggggcaga agtccagtgg gccttctgaa
     4861 agcaaagaat cttcagatga attagatatc gatgagacgg catcggacat gagcatgagc
     4921 ccacagagtt cttcattacc agcaggagat ggtcagctgg aagaggaagg gaagggccac
     4981 aagcggcctg ttggcatgct ggtccgcatg gcctctgccc ccagcgggaa cgtggcagac
     5041 tcaactcttc ttctcacgga catggcagat ttccagcaga ttcttcagtt ccccagtctg
     5101 cggacaacaa ctactgtgag ttggtgcttc ttgaattata caaaacccaa ttatgtgcaa
     5161 caggccacct tcaaatcctc ggtttatgct tcatggtgca ttagttcctg taatccaaac
     5221 ccatcaggat tgaacaccaa gaccacgctg gctcttctga ggtccaagca aaaaatcact
     5281 gcagaaattt atactctggc tgctatgcat aggcctggaa ccggcaagct tacatcatca
     5341 agtgcttgga agcagtttac tcagatgaaa cctgatgcgt cctttttatt tggcagcaaa
     5401 ctagaaagga aactagtggg aaatatctta aaggaaagag ggaaaggaga tattcatgga
     5461 gataaagata ttggatccaa acaaactgag ccaatccgaa ttaaaatatt tgaaggaggg
     5521 tacaaatcga atgaagatta tgtatatgtc agaggacgtg gccggggaaa gtacatttgt
     5581 gaagaatgtg ggattcgctg taagaagcca agcatgctca aaaaacacat ccgtacccat
     5641 actgatgttc ggccttatgt atgcaagtta tgtaactttg ccttcaaaac gaaaggaaac
     5701 ctaacgaagc atatgaaatc taaagcacac atgaaaaaat gcctggaatt gggagtctca
     5761 atgacatcgg tggatgatac agaaactgag gaagcagaaa atttggaaga tttgcacaaa
     5821 gcagcagaga agcatagcat gtccagcatt tcaactgatc atcagttctc cgatgctgag
     5881 gaatcagatg gtgaggatgg agatgataat gatgatgatg atgaagatga agatgacttt
     5941 gacgaccagg gagatttaac accaaaaaca agatcaagaa gcaccagtcc tcagcctcct
     6001 agattctcct ccttgcctgt gaatgttggc gccgtacccc acggggttcc ttcagatagt
     6061 tccctgggac attcttcgtt gatcagctat ttggttactt tgccaagtat tcgagttact
     6121 cagcttatga cacccagtga ttcatgtgaa gatacccaga tgacagaata ccagaggcta
     6181 ttccagagca aaagtacgga ctcagaacca gacaaagaca gattggacat acctagttgt
     6241 atggatgagg agtgcatgct accttcagag ccaagctcct ctcccaggga cttctcaccc
     6301 tcaagccacc attcctctcc aggatatgat tcttcaccct gtcgagataa ttcaccaaag
     6361 aggtatctga tacccaaagg agatttatct cccaggagac atttatcacc taggagagat
     6421 ctgtcaccca tgagacatct ttcaccaaca aaggaagctg cattgagaag agagatgtcc
     6481 caaagagatg tttcaccaag aaggcatttg tctccaagga ggccagtgtc tcctgggaaa
     6541 gatatcacag caagaagaga cctctcccct agaagagaga gaagatacat gaccacaata
     6601 agagcgccat ctcccagaag ggctttatac cataacccac cattgtccat gggacagtat
     6661 ttgcaagcag agccaattgt attggggcct cctaatttaa gaagaggatt acctcaggtt
     6721 ccttacttca gtctctatgg agaccaagaa ggtgcttatg aacatccagg ctccagcctt
     6781 ttccctgagg gtcctaatga ctatgtcttc agtcatcttc cactccactc tcagcaacaa
     6841 gtgcgagccc ctatccccat ggtgcccgtt ggtgggatcc agatggttca ctccatgccg
     6901 ccagcccttt ccagtttaca tccttcaccc acattgcccc tgccaatgga gggctttgag
     6961 gagaagaaag gcgcgtcagg ggagtccttc tccaaggacc cctatgtgct ttctaagcag
     7021 catgagaagc gaggtcctca cgctttgcag tcatctggtc cgcctagcac tccctcctct
     7081 cctcggctgt tgatgaaaca gagcacttcg gaagacagcc taaacgcaac agagcgggaa
     7141 caggaggaaa atatacagac ttgtacaaaa gccattgcct ctctccggat tgccacggaa
     7201 gaggcagctc tgctcgggcc agatcagcca gcgcgggtgc aggagcccca ccagaacccc
     7261 ctgggaagtg cacatgttag cattagacac tttagtagac ctgagccagg tcagccctgt
     7321 acctcagcca cccaccctga cttgcatgat ggtgaaaagg acaattttgg tacatcacag
     7381 actccattag ctcactccac gttttacagc aagagttgtg tggatgacaa gcagttggac
     7441 tttcacagca gcaaggaatt atcttcaagc acagaggaaa gcaaagatcc ttcatcagaa
     7501 aagagtcagc tacattgatc tatgatgcat ggagactttc atttccacat tttcccattt
     7561 ttttgttttt gtttttctag aaatggaggt aatccagttt atagcatgcc tgtcctaagt
     7621 tacagtagtt tgctattata tatacttttg ttatatcaaa agaattaggt aaattaacaa
     7681 gtcatcatga gcctgaccaa aacaaaattt gaaattaacc tattgggtct ggtactttta
     7741 aaattgtaca gatgtttgtg ccttttcttt actttgctta tattcttata agcatttttt
     7801 agcagtaatt tgtacatatt ttagaatttg tgtatctgct ttgtaataaa tgtaatttct
     7861 ttcctttttt ggacacttgg atctaaatga tgtaaagcaa aacagcatca atatatatgt
     7921 gaggttgcac taaaacatat ttttatatga ttaaaactga acagctttta tgtacagctc
     7981 tgattctgta atactaatat ttatttactt tgtttcataa attgtacatt ttttcttaat
     8041 gttgtggatt gcttttctat gtgaagcatg ggatttactg ttgcgtaact agaacaaaaa
     8101 tgtacattgt aaacaagata tttaaactag agtatcttat tctgcactta tgcattagtt
     8161 aaaaaaagat aaaggatgta tcagtcagtt cttaactctt gtatattttt ttgtctcttg
     8221 tttgctggat tgactataac ttaagtgctg attgtgattt taaaatgata gtaccgtaaa
     8281 gcattaaagt aaacaatgtg ctattgtgag ttttttcaaa gctttataaa tcagttataa
     8341 ataatattaa aagtatttgg tcttatgtga acatgttgat ctatatactc atctaaaaat
     8401 atgggaaaac attccacccc atgtaaatat gtacaagtgc atcactggta caattttatg
     8461 taactcagtt ggacactagg ttgccacaga cctatgctag gtgtctttaa aaaattaagg
     8521 tgacaaagca catgggactg tgtagagctt ggttatcggc cggcccggtg gcttggcagg
     8581 cagtctgtcg ctgctcatgg agaagacctg ggcttagcaa tctccttagt tcttgctaca
     8641 caggatggtg actggaacta aggctacaca gagggtcgca cttggactct gagggttggg
     8701 tgtggaaggg ggaaaagggg atggagacct gctccccagc tcttcctgtc agccggttta
     8761 catgggaaca gggttaacat ctgtgttagg ggaggtcacc ttaccctttt tcatagggga
     8821 agagtgtcac actcctggct atctcagggg gaatggggaa aagaatcttt caagggcaaa
     8881 gaactcgtgg gaggatgtct gttgtatgta atactcacaa tggcttttgg ttagtgttga
     8941 aggtgggaag agcatttgta ggtccagaag agtgaaagag agggaggggt gcagcaacat
     9001 gtgcacaggc acgcacatgt gtgcacgcac acatacaatc tgggttatct ttgtgctata
     9061 tagtggatta taattctgtg aaaccaagtt tgtatattga attacattaa ggagtgttct
     9121 ttaaaaagag aaataaatat acaattacat gcttaaaaaa aaaaaaaaaa aaaaa
//