From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human prothymosin-alpha gene, complete cds.
Date: 24 Jul 92 10:07:13 GMT
Distribution: bionet
Checksum: 41419     6

LOCUS       HUMPROAA2    2308 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  Human prothymosin-alpha gene, complete cds.
ACCESSION   M67480
KEYWORDS    prothymosin-alpha.
SEGMENT     2 of 2
SOURCE      Human lymphocyte cell line RPMI 8226 DNA, clone p3.28.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2308)
  AUTHORS   Eschenfeldt,W.H., Manrow,R.E., Krug,M.S. and Berger,S.L.
  TITLE     Isolation and partial sequencing of the human prothymosin alpha
            gene family: Evidence against export of the gene products
  JOURNAL   J. Biol. Chem. 264, 7546-7555 (1989)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             join(J04797:453..497,45..116,582..678,1138..1211,
                     1497..1544)
                     /product="prothymosin-alpha"
                     /gene="PTMA"
                     /codon_start=1
                     /translation="MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAENEEN
                     GEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDT
                     KKQKTDEDD"
     CDS             join(J04797:453..497,45..116,585..678,1138..1211,
                     1497..1544)
                     /product="prothymosin-alpha"
                     /gene="PTMA"
                     /codon_start=1
                     /translation="MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNANEENG
                     EQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTK
                     KQKTDEDD"
     exon            45..116
                     /number=2
                     /product="prothymosin-alpha"
                     /gene="PTMA"
     exon            582..678
                     /number=3
                     /product="prothymosin-alpha"
                     /gene="PTMA"
     exon            585..678
                     /number=3
                     /note="alternative start for"
                     /product="prothymosin-alpha"
                     /gene="PTMA"
     exon            1138..1211
                     /number=4
                     /product="prothymosin-alpha"
                     /gene="PTMA"
     exon            1497..2228
                     /number=5
                     /product="prothymosin-alpha"
                     /gene="PTMA"
     polyA_signal    2254..2259
                     /gene="PTMA"
BASE COUNT      563 a    475 c    660 g    610 t
ORIGIN
        1 ctcagaagac ttactggtta ctggttcctt cttccctttt gaaggactta aaggagaaga
       61 aggaagttgt ggaagaggca gaaaatggaa gagacgcccc tgctaacggg aatgctgtga
      121 gtgtctgctt tgctcctgag ccctggcagc taccgcccca caaaattttt cctgttctac
      181 tttaaacata cctatatatg tgtgtgtatg tgtatatgta tagctttgca cagtggcagt
      241 atcgtagcca atgagcttta cccgaggcgc gattattgct agttaaatat ttataaaaac
      301 ctttcgagca gcgcctgaac aagaataggt tcagaggaga ctccggtatc tgagtttggg
      361 cttggccagg gtggggaaaa gcccttgttc ctgggcagtt aatgtgcagg tttcatgatg
      421 gagcctggag ggtgttgact ggagaagggt ctctggggtg ggcttggctt ggctgggctg
      481 tagatgcagc cgccagcctc tggtgggagg ccgggcatca ggagcaacgc tctgtccagc
      541 ctggggccag ctggtaatga catggcctgt tttctgtcga ggagaatgag gaaaatgggg
      601 agcaggaggc tgacaatgag gtagacgaag aagaggaaga aggtggggag gaagaggagg
      661 aggaagaaga aggtgatggt gagtagcctt gtctatcttc cccttttcag gtactttttc
      721 ctggccttgt ctggcagaag gggaaggaag gaattggggc tcctgggagt gggacaatgg
      781 tacttggggc cagtggacca catggccctg ggcacccacc tgtagagtca gggaaggtct
      841 ccctgacatg gagttgtgcc catgcccact cacactcact cgcacacctg aaagtttctt
      901 tcgtgcagct ctgaaagcca ctgatctatt gggctggcct tttggggtgc agctgcttgg
      961 gcctctctcc tctggagagt cccacctgtg tagtgggcgt gggtgccctg attgggccca
     1021 gttgcaggca gtagaggcag ggcagggacc ttgcagtcca ctacatgttc ctcgggattt
     1081 ccccaggagc cacagtagga gggaagtgtg gtttacctgg cctttgattc tctccaggtg
     1141 aggaagagga tggagatgaa gatgaggaag ctgagtcagc tacgggcaag cgggcagctg
     1201 aagatgatga ggtgggttct ggcttgagaa gaaggggggt ttggcatctg ggtctcccca
     1261 cctgccttta gctgaggtgc tcaagctgcg gagggactgt ttctgacttt gtaggtggcc
     1321 atgtgtgtcc tgaatcttaa gaacaggaag gaaacagggc tgggctcaac ttcccagagg
     1381 ccttgggctg tggagctggg ggtccctggt tcttgctctg ccagcaggag ctgaggcagt
     1441 gggctggata gggctcctgg ggttggaggg gcctttgaca gtctttctct gcttaggatg
     1501 acgatgtcga taccaagaag cagaagaccg acgaggatga ctagacagca aaaaaggaaa
     1561 agttaaacta aaaaaaaaaa ggccgccgtg acctattcac cctccacttc ccgtctcaga
     1621 atctaaacgt ggtcaccttc gagtagagag gcccgcccgc ccaccgtggg cagtgccacc
     1681 cgcagatgac acgcgctctc caccacccaa cccaaaccat gagaatttgc aacaggggag
     1741 gaaaaaagaa ccaaaacttc caaggccctg ctttttttct taaaagtact ttaaaaagga
     1801 aatttgtttg tattttttat ttacatttta tatttttgta catattgtta gggtcagcca
     1861 tttttaatga tctcggatgg ccaaaccagc cttcggagcg ttctctgtcc tacttctgac
     1921 tttacttgtg gtgtgacatg ttcattataa tctcaaagga gaaaaaaaac cttgtaaaaa
     1981 aagcaaaaat gacaacagaa aaacaatctt attccgagca ttccagtaac ttttttgtgt
     2041 atgtacttag ctgtactata agtagttggt ttgtatgaga tggttaaaaa ggccaaagat
     2101 aaaaggtttc tttttttttc cttttttgtc tatgaagttg ctgtttattt tttttggcct
     2161 gtttgatgta tgtgtgaaac aatgttgtcc aacaataaac aggaatttta ttttgctgag
     2221 ttgttctaac aaagctgtct caagcctggt ttttctgttt cagtttcttc agaccttcca
     2281 gggcacaagg ataggagggg gaggatcc
//