From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for E-cadherin
Date: 15 Aug 92 10:02:07 GMT
Distribution: bionet
Checksum: 23820     9

LOCUS       HUMECAD      4778 bp ss-RNA             PRI       15-AUG-1992
DEFINITION  H.sapiens mRNA for E-cadherin
ACCESSION   Z13009
KEYWORDS    E-cadherin.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4778)
  AUTHORS   Bussemakers,M.J., Mees,S.G., Van Bokhoven,A., Debruyne,F.M. and
            Schalken,J.A.
  TITLE     Cloning and characterization of the human E-cadherin cDNA
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 4778)
  AUTHORS   Bussemakers,M.J.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT
            From EMBL    entry HSECAD;  dated 06-AUG-1992.
FEATURES             Location/Qualifiers
     mRNA            1..4778
     CDS             95..2743
                     /product="E-cadherin"
                     /codon_start=1
                     /translation="MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRR
                     HLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYA
                     WDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPP
                     ISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTE
                     PLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGAL
                     PGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLD
                     RESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVV
                     ITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQY
                     ILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSY
                     TAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALII
                     ATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTS
                     PFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLE
                     VSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEP
                     LLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYL
                     PRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKD
                     QDYDYLNEWGNRFKKLADMYGGGEDD"
     mat_peptide     557..2740
                     /product="E-cadherin"
BASE COUNT     1237 a   1177 c   1128 g   1236 t
ORIGIN
        1 gcttgcggaa gtcagttcag actccagccc gctccagccc ggcccgaccc gaccgcaccc
       61 ggcgcctgcc ctcgctcggc gtccccggcc agccatgggc ccttggagcc gcagcctctc
      121 ggcgctgctg ctgctgctgc aggtctcctc ttggctctgc caggagccgg agccctgcca
      181 ccctggcttt gacgccgaga gctacacgtt cacggtgccc cggcgccacc tggagagagg
      241 ccgcgtcctg ggcagagtga attttgaaga ttgcaccggt cgacaaagga cagcctattt
      301 ttccctcgac acccgattca aagtgggcac agatggtgtg attacagtca aaaggcctct
      361 acggtttcat aacccacaga tccatttctt ggtctacgcc tgggactcca cctacagaaa
      421 gttttccacc aaagtcacgc tgaatacagt ggggcaccac caccgccccc cgccccatca
      481 ggcctccgtt tctggaatcc aagcagaatt gctcacattt cccaactcct ctcctggcct
      541 cagaagacag aagagagact gggttattcc tcccatcagc tgcccagaaa atgaaaaagg
      601 cccatttcct aaaaacctgg ttcagatcaa atccaacaaa gacaaagaag gcaaggtttt
      661 ctacagcatc actggccaag gagctgacac accccctgtt ggtgtcttta ttattgaaag
      721 agaaacagga tggctgaagg tgacagagcc tctggataga gaacgcattg ccacatacac
      781 tctcttctct cacgctgtgt catccaacgg gaatgcagtt gaggatccaa tggagatttt
      841 gatcacggta accgatcaga atgacaacaa gcccgaattc acccaggagg tctttaaggg
      901 gtctgtcatg gaaggtgctc ttccaggaac ctctgtgatg gaggtcacag ccacagacgc
      961 ggacgatgat gtgaacacct acaatgccgc catcgcttac accatcctca gccaagatcc
     1021 tgagctccct gacaaaaata tgttcaccat taacaggaac acaggagtca tcagtgtggt
     1081 caccactggg ctggaccgag agagtttccc tacgtatacc ctggtggttc aagctgctga
     1141 ccttcaaggt gaggggttaa gcacaacagc aacagctgtg atcacagtca ctgacaccaa
     1201 cgataatcct ccgatcttca atcccaccac gtacaagggt caggtgcctg agaacgaggc
     1261 taacgtcgta atcaccacac tgaaagtgac tgatgctgat gcccccaata ccccagcgtg
     1321 ggaggctgta tacaccatat tgaatgatga tggtggacaa tttgtcgtca ccacaaatcc
     1381 agtgaacaac gatggcattt tgaaaacagc aaagggcttg gattttgagg ccaagcagca
     1441 gtacattcta cacgtagcag tgacgaatgt ggtacctttt gaggtctctc tcaccacctc
     1501 cacagccacc gtcaccgtgg atgtgctgga tgtgaatgaa gcccccatct ttgtgcctcc
     1561 tgaaaagaga gtggaagtgt ccgaggactt tggcgtgggc caggaaatca catcctacac
     1621 tgcccaggag ccagacacat ttatggaaca gaaaataaca tatcggattt ggagagacac
     1681 tgccaactgg ctggagatta atccggacac tggtgccatt tccactcggg ctgagctgga
     1741 cagggaggat tttgagcacg tgaagaacag cacgtacaca gccctaatca tagctacaga
     1801 caatggttct ccagttgcta ctggaacagg gacacttctg ctgatcctgt ctgatgtgaa
     1861 tgacaacgcc cccataccag aacctcgaac tatattcttc tgtgagagga atccaaagcc
     1921 tcaggtcata aacatcattg atgcagacct tcctcccaat acatctccct tcacagcaga
     1981 actaacacac ggggcgagtg ccaactggac cattcagtac aacgacccaa cccaagaatc
     2041 tatcattttg aagccaaaga tggccttaga ggtgggtgac tacaaaatca atctcaagct
     2101 catggataac cagaataaag accaagtgac caccttagag gtcagcgtgt gtgactgtga
     2161 aggggccgcc ggcgtctgta ggaaggcaca gcctgtcgaa gcaggattgc aaattcctgc
     2221 cattctgggg attcttggag gaattcttgc tttgctaatt ctgattctgc tgctcttgct
     2281 gtttcttcgg aggagagcgg tggtcaaaga gcccttactg cccccagagg atgacacccg
     2341 ggacaacgtt tattactatg atgaagaagg aggcggagaa gaggaccagg actttgactt
     2401 gagccagctg cacaggggcc tggacgctcg gcctgaagtg actcgtaacg acgttgcacc
     2461 aaccctcatg agtgtccccc ggtatcttcc ccgccctgcc aatcccgatg aaattggaaa
     2521 ttttattgat gaaaatctga aagcggctga tactgacccc acagccccgc cttatgattc
     2581 tctgctcgtg tttgactatg aaggaagcgg ttccgaagct gctagtctga gctccctgaa
     2641 ctcctcagag tcagacaaag accaggacta tgactacttg aacgaatggg gcaatcgctt
     2701 caagaagctg gctgacatgt acggaggcgg cgaggacgac taggggactc gagagaggcg
     2761 ggccccagac ccatgtgctg ggaaatgcag aaatcacgtt gctggtggtt tttcagctcc
     2821 cttcccttga gatgagtttc tggggaaaaa aaagagactg gttagtgatg cagttagtat
     2881 agctttatac tctctccact ttatagctct aataagtttg tgttagaaaa gtttcgactt
     2941 atttcttaaa gctttttttt ttttcccatc actctttaca tggtggtgat gtccaaaaga
     3001 tacccaaatt ttaatattcc agaagaacaa ctttagcatc agaaggttca cccagcacct
     3061 tgcagatttt cttaaggaat tttgtctcac ttttaaaaag aaggggagaa gtcagctact
     3121 ctagttctgt tgttttgtgt atataatttt ttaaaaaaaa tttgtgtgct tctgctcatt
     3181 actacactgg tgtgtccctc tgcctttttt ttttttttta agacagggtc tcattctatc
     3241 ggccaggctg gagtgcagtg gtgcaatcac agctcactgc agccttgtcc tcccaggctc
     3301 aagctatcct tgcacctcag cctcccaagt agctgggacc acaggcatgc accactacgc
     3361 atgactaatt ttttaaatat ttgagacggg gtctccctgt gttacccagg ctggtctcaa
     3421 actcctgggc tcaagtgatc ctcccatctt ggcctcccag agtattggga ttacagacat
     3481 gagccactgc acctgcccag ctccccaact ccctgccatt ttttaagaga cagtttcgct
     3541 ccatcgccca ggcctgggat gcagtgatgt gatcatagct cactgtaacc tcaaactctg
     3601 gggctcaagc agttctccca ccagcctcct ttttattttt ttgtacagat ggggtcttgc
     3661 tatgttgccc aagctggtct taaactcctg gcctcaagca atccttctgc cttggccccc
     3721 caaagtgctg ggattgtggg catgagctgc tgtgcccagc ctccatgttt taatatcaac
     3781 tctcactcct gaattcagtt gctttgccca agataggagt tctctgatgc agaaattatt
     3841 gggctctttt agggtaagaa gtttgtgtct ttgtctggcc acatcttgac taggtattgt
     3901 ctactctgaa gacctttaat ggcttccctc tttcatctcc tgagtatgta acttgcaatg
     3961 ggcagctatc cagtgacttg ttctgagtaa gtgtgttcat taatgtttat ttagctctga
     4021 agcaagagtg atatactcca ggacttagaa tagtgcctaa agtgctgcag ccaaagacag
     4081 agcggaacta tgaaaagtgg gcttggagat ggcaggagag cttgtcattg agcctggcaa
     4141 tttagcaaac tgatgctgag gatgattgag gtgggtctac ctcatctctg aaaattctgg
     4201 aaggaatgga ggagtctcaa catgtgtttc tgacacaaga tccgtggttt gtactcaaag
     4261 cccagaatcc ccaagtgcct gcttttgatg atgtctacag aaaatgctgg ctgagctgaa
     4321 cacatttgcc caattccagg tgtgcacaga aaaccgagaa tattcaaaat tccaaatttt
     4381 ttcttaggag caagaagaaa atgtggccct aaagggggtt agttgagggg tagggggtag
     4441 tgaggatctt gatttggatc tctttttatt taaatgtgaa tttcaacttt tgacaatcaa
     4501 agaaaagact tttgttgaaa tagctttact gtttctcaag tgttttggag aaaaaaatca
     4561 accctgcaat cactttttgg aattgtcttg atttttcggc agttcaagct atatcgaata
     4621 tagttctgtg tagagaatgt cactgtagtt ttgagtgtat acatgtgtgg gtgctgataa
     4681 ttgtgtattt tctttggggg tggaaaagga aaacaattca agctgagaaa agtattctca
     4741 aagatgcatt tttataaatt ttattaaaca attttgtt
//