From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for laminin
Date: 21 Dec 92 20:46:43 GMT
Distribution: bionet
Checksum: 08998 9

LOCUS       HUMLAMB2TB   4316 bp ss-RNA             PRI       17-NOV-1992
DEFINITION  H.sapiens mRNA for laminin
ACCESSION   Z15009
KEYWORDS    laminin.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4316)
  AUTHORS   Kallunki,P., Sainio,K., Eddy,R., Byers,M., Kallunki,T., Sariola,H.,
            Beck,K.F., Hirvonen,H., Shows,T.B. and Tryggvason,K.
  TITLE     A truncated laminin chain homologous to the B2 chain: Structure,
            spatial expression and chromosomal assignment.
  JOURNAL   J. Cell Biol. 119, 679-693 (1992)
  STANDARD  full automatic
COMMENT     *source: cell_type=Fibrosarcoma; *source: cell_line=HT-1080;
            *source: chromosome=1;
               From EMBL    entry HSLAMB2TB;  dated 09-NOV-1992.
FEATURES             Location/Qualifiers
     sig_peptide     118..183
     repeat_unit     4021..4316
                     /rpt_family="Human Alu"
                     /rpt_type=other
     polyA_site      4296
     CDS             118..3453
                     /product="Laminin"
                     /codon_start=1
                     /translation="MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELH
                     RQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC
                     SCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPA
                     VTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGW
                     KAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVD
                     RGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYF
                     EYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQF
                     CQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFY
                     NDPHDPRSCKPCPCHNGFSCSVIPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH
                     GPVRPCQPCQCNSNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP
                     ADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFM
                     QQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLA
                     KVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNT
                     NIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALH
                     EGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVS
                     PLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGK
                     SGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEA
                     MKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNL
                     EANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRA
                     KNAGVTIQDTLNTLDGLLHLMGM"
BASE COUNT     1158 a   1033 c   1226 g    899 t
ORIGIN      
        1 gaccacctga tcgaaggaaa aggaaggcac agcggagcgc agagtgagaa ccaccaaccg
       61 aggcgccggg cagcgacccc tgcagcggag acagagactg agcggcccgg caccgccatg
      121 cctgcgctct ggctgggctg ctgcctctgc ttctcgctcc tcctgcccgc agcccgggcc
      181 acctccagga gggaagtctg tgattgcaat gggaagtcca ggcagtgtat ctttgatcgg
      241 gaacttcaca gacaaactgg taatggattc cgctgcctca actgcaatga caacactgat
      301 ggcattcact gcgagaagtg caagaatggc ttttaccggc acagagaaag ggaccgctgt
      361 ttgccctgca attgtaactc caaaggttct cttagtgctc gatgtgacaa ctctggacgg
      421 tgcagctgta aaccaggtgt gacaggagcc agatgcgacc gatgtctgcc aggcttccac
      481 atgctcacgg atgcggggtg cacccaagac cagagactgc tagactccaa gtgtgactgt
      541 gacccagctg gcatcgcagg gccctgtgac gcgggccgct gtgtctgcaa gccagctgtt
      601 actggagaac gctgtgatag gtgtcgatca ggttactata atctggatgg ggggaaccct
      661 gagggctgta cccagtgttt ctgctatggg cattcagcca gctgccgcag ctctgcagaa
      721 tacagtgtcc ataagatcac ctctaccttt catcaagatg ttgatggctg gaaggctgtc
      781 caacgaaatg ggtctcctgc aaagctccaa tggtcacagc gccatcaaga tgtgtttagc
      841 tcagcccaac gactagatcc tgtctatttt gtggctcctg ccaaatttct tgggaatcaa
      901 caggtgagct atgggcaaag cctgtccttt gactaccgtg tggacagagg aggcagacac
      961 ccatctgccc atgatgtgat cctggaaggt gctggtctac ggatcacagc tcccttgatg
     1021 ccacttggca agacactgcc ttgtgggctc accaagactt acacattcag gttaaatgag
     1081 catccaagca ataattggag cccccagctg agttactttg agtatcgaag gttactgcgg
     1141 aatctcacag ccctccgcat ccgagctaca tatggagaat acagtactgg gtacattgac
     1201 aatgtgaccc tgatttcagc ccgccctgtc tctggagccc cagcaccctg ggttgaacag
     1261 tgtatatgtc ctgttgggta caaggggcaa ttctgccagg attgtgcttc tggctacaag
     1321 agagattcag cgagactggg gccttttggc acctgtattc cttgtaactg tcaaggggga
     1381 ggggcctgtg atccagacac aggagattgt tattcagggg atgagaatcc tgacattgag
     1441 tgtgctgact gcccaattgg tttctacaac gatccgcacg acccccgcag ctgcaagcca
     1501 tgtccctgtc ataacgggtt cagctgctca gtgattccgg agacggagga ggtggtgtgc
     1561 aataactgcc ctcccggggt caccggtgcc cgctgtgagc tctgtgctga tggctacttt
     1621 ggggacccct ttggtgaaca tggcccagtg aggccttgtc agccctgtca atgcaacagc
     1681 aatgtggacc ccagtgcctc tgggaattgt gaccggctga caggcaggtg tttgaagtgt
     1741 atccacaaca cagccggcat ctactgcgac cagtgcaaag caggctactt cggggaccca
     1801 ttggctccca acccagcaga caagtgtcga gcttgcaact gtaaccccat gggctcagag
     1861 cctgtaggat gtcgaagtga tggcacctgt gtttgcaagc caggatttgg tggccccaac
     1921 tgtgagcatg gagcattcag ctgtccagct tgctataatc aagtgaagat tcagatggat
     1981 cagtttatgc agcagcttca gagaatggag gccctgattt caaaggctca gggtggtgat
     2041 ggagtagtac ctgatacaga gctggaaggc aggatgcagc aggctgagca ggcccttcag
     2101 gacattctga gagatgccca gatttcagaa ggtgctagca gatcccttgg tctccagttg
     2161 gccaaggtga ggagccaaga gaacagctac cagagccgcc tggatgacct caagatgact
     2221 gtggaaagag ttcgggctct gggaagtcag taccagaacc gagttcggga tactcacagg
     2281 ctcatcactc agatgcagct gagcctggca gaaagtgaag cttccttggg aaacactaac
     2341 attcctgcct cagaccacta cgtggggcca aatggcttta aaagtctggc tcaggaggcc
     2401 acaagattag cagaaagcca cgttgagtca gccagtaaca tggagcaact gacaagggaa
     2461 actgaggact attccaaaca agccctctca ctggtgcgca aggccctgca tgaaggagtc
     2521 ggaagcggaa gcggtagccc ggacggtgct gtggtgcaag ggcttgtgga aaaattggag
     2581 aaaaccaagt ccctggccca gcagttgaca agggaggcca ctcaagcgga aattgaagca
     2641 gataggtctt atcagcacag tctccgcctc ctggattcag tgtctccgct tcagggagtc
     2701 agtgatcagt cctttcaggt ggaagaagca aagaggatca aacaaaaagc ggattcactc
     2761 tcaagcctgg taaccaggca tatggatgag ttcaagcgta cacaaaagaa tctgggaaac
     2821 tggaaagaag aagcacagca gctcttacag aatggaaaaa gtgggagaga gaaatcagat
     2881 cagctgcttt cccgtgccaa tcttgctaaa agcagagcac aagaagcact gagtatgggc
     2941 aatgccactt tttatgaagt tgagagcatc cttaaaaacc tcagagagtt tgacctgcag
     3001 gtggacaaca gaaaagcaga agctgaagaa gccatgaaga gactctccta catcagccag
     3061 aaggtttcag atgccagtga caagacccag caagcagaaa gagccctggg gagcgctgct
     3121 gctgatgcac agagggcaaa gaatggggcc ggggaggccc tggaaatctc cagtgagatt
     3181 gaacaggaga ttgggagtct gaacttggaa gccaatgtga cagcagatgg agccttggcc
     3241 atggaaaagg gactggcctc tctgaagagt gagatgaggg aagtggaagg agagctggaa
     3301 aggaaggagc tggagtttga cacgaatatg gatgcagtac agatggtgat tacagaagcc
     3361 cagaaggttg ataccagagc caagaacgct ggggttacaa tccaagacac actcaacaca
     3421 ttagacggcc tcctgcatct gatgggtatg tgaacccaca acccacaacc ttccagctcc
     3481 atgctccagg gctttgctcc agaacactca ctatacctag ccccagcaaa ggggagtctc
     3541 agctttcctt aaggatatca gtaaatgtgc tttgtttcca ggcccagata actttcggca
     3601 ggttccctta catttactgg accctgtttt accgttgcta agatgggtca ctgaacacct
     3661 attgcacttg ggggtaaagg tctgtgggcc aaagaacagg tgtatataag caacttcaca
     3721 gaacacgaga cagcttggga atcctgctaa agagtctggc ctggaccctg agaagccagt
     3781 ggacagtttt aagcagagga ataacatcac cactgtatat ttcagaaaga tcactagggc
     3841 agccgagtgg aggaaagctt gaagaggggg ttagagagaa ggcaggttga gactacttaa
     3901 gatattgttg aaataattga agagagaaat gacaggagcc tgctctaagg cagtagaatg
     3961 gtggctggga agatgtgaag gaagattttc ccagtctgtg aagtcaagaa tcacttgccg
     4021 gccgggtgtg gtggctcacg cctgtaattc tagcactttg ggagactgaa gcgggtggat
     4081 cacccgaggt caggagttga agaccagcct ggccaacatg gtgaaaccct gtctctacta
     4141 aaagtacaaa aattagctgg atgatggtgg tgggcgcctg taattccagc tactcaggag
     4201 tctgaggcag gagaatcgct tgaacccagg aggcgaggtt acagtgagcc aagattgcac
     4261 cactgctctt ccagcctggg aacagagaga ctgcctaaaa aaaaaaaaaa aaaaaa
//