From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse protein disulfide isomerase (ERp59) mRNA, complete cds.
Date: 6 Nov 92 18:31:33 GMT
Distribution: bionet
Checksum: 27912 6

LOCUS       MUSPDIA      2537 bp ss-mRNA            ROD       02-NOV-1992
DEFINITION  Mouse protein disulfide isomerase (ERp59) mRNA, complete cds.
ACCESSION   J05185
KEYWORDS    luminal endoplasmic reticulum protein; protein disulfide isomerase.
SOURCE      Mouse fibroblast, cDNA to mRNA, clone pcD59-11.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2537)
  AUTHORS   Mazzarella,R.A., Srinivasan,M., Haugejorden,S.M. and Green,M.
  TITLE     ERp72, an abundant luminal endoplasmic reticulum protein, contains
            three copies of the active site sequences of protein disulfide
            isomerase
  JOURNAL   J. Biol. Chem. 265, 1094-1101 (1990)
  STANDARD  full automatic
COMMENT     Draft entry and computer-readable sequence for [1] kindly submitted
            by M.Srinivasan, 03-JAN-1990.
FEATURES             Location/Qualifiers
     sig_peptide     130..186
                     /codon_start=1
     mat_peptide     187..1656
                     /product="protein disulfide isomerase"
                     /codon_start=1
     polyA_signal    2518..2523
     CDS             130..1658
                     /EC_number="5.3.4.1"
                     /partial
                     /product="protein disulfide isomerase"
                     /codon_start=1
                     /translation="MLSRALLCLALAWAARVGADALEEEDNVLVLKKSNFEEALAAHK
                     YLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYP
                     TIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVI
                     GFFKDVESDSAKQFLLAAEAIDDIPFGITSNSGVFSKYQLDKDGVVLFKKFDEGRNNF
                     EGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSS
                     FKRAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESD
                     ELTAEKITEFCHRFLEGKIKPHLMSQEVPEDWDKQPVKVLVGANFEEVAFDEKKNVFV
                     EFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPA
                     SADRTVIDYNGERTLDGFKKFLESGGQDGAGDDEDLDLEEALEPDMEEDDDQKAVKDE
                     L"
BASE COUNT      615 a    626 c    699 g    597 t
ORIGIN      
        1 agggggaggc gtgggcgcgt ccccggccca ggatttataa aggcgaggtc tggaccgacg
       61 cgcgctctcg tcgccttggc tgtcccggcg gcgccaaccc aactgccccg cccgctgcag
      121 acgtccgaca tgctgagccg tgctttgctg tgcctagccc tggcctgggc ggctagggtg
      181 ggcgccgacg ccctggagga ggaggacaac gtcctggtgt tgaagaagag caacttcgag
      241 gaggcgctgg cggcgcacaa gtacctgctg gtggagttct atgccccgtg gtgtggccac
      301 tgcaaagctc tggctcccga gtatgccaaa gctgccgcaa aactgaaggc agaaggctct
      361 gagattcgac tagcaaaggt ggatgccaca gaagagtctg acctggctca gcagtatggt
      421 gtccgtggct accccacaat caagttcttc aagaatggag acacagcctc cccaaaggaa
      481 tatacagctg gcagggaagc tgatgacatt gtcaactggc tgaagaaacg cacgggccca
      541 gcagctacaa ccctgtctga cactgcagct gcagagtcct tggtggactc aagcgaagtg
      601 acggtcatcg gtttcttcaa ggacgtagag tcagactctg ccaagcagtt cttgctggca
      661 gcagaggcta ttgatgacat accttttgga atcacgtcca acagtggtgt gttctccaag
      721 taccagctgg acaaagatgg ggtggtcctc tttaagaagt ttgatgaagg ccgcaacaac
      781 tttgagggtg agatcaccaa ggagaagctt ctagacttca tcaagcacaa ccagctgcct
      841 ttggtcatcg agttcactga acagacagct ccgaagattt ttggaggtga gatcaagaca
      901 cacattctgc tgttcctgcc caagagtgta tctgactatg acggcaagct gagcagcttc
      961 aagagagcag ccgagggctt caagggcaag atcctattta tcttcatcga tagcgaccac
     1021 actgataacc agcgcatact tgagttcttt ggcctgaaga aggaggagtg tcccgccgtg
     1081 cggcttatta ccctagagga agagatgacc aagtacaaac cagagtcaga tgagctgacg
     1141 gctgagaaaa tcacagagtt ttgccaccgc ttcttagagg gcaagatcaa gccccacctg
     1201 atgagccagg aagtgcctga agactgggac aaacagccgg taaaagtact ggttggggcg
     1261 aactttgaag aggtcgcttt tgatgagaaa aagaacgtgt ttgttgaatt ctatgcccct
     1321 tggtgtggtc actgcaagca gctagccccc atttgggata aactgggaga gacatacaag
     1381 gatcatgaga atatcatcat tgctaagatg gactcaacag ccaatgaggt ggaagctgtc
     1441 aaagtacata gctttcccac actgaagttc ttcccagcaa gtgcagacag aacggtcatt
     1501 gattacaatg gcgagcggac actggacggt tttaagaaat tcttggagag tggtggccag
     1561 gatggagcag gggacgatga ggacctcgac ctagaagaag ctttagagcc agacatggag
     1621 gaagacgacg atcagaaagc tgtgaaggat gaactgtagt gcagaagcca gatctgggcg
     1681 cctgaaccca aaacctcggt gggccacgct cccagcagcc cacatctccg gagcctgagc
     1741 ctcaccccag gagggagcgc catcagaacc cagggaatct ttctgaagcc acactcatct
     1801 gacacacgta cacttagacc tgtctcttct tttgcttttc aattttggaa agggatctct
     1861 gtccaggtca gcccctcttg aagggctacc ttttgtttta attggtggtg tacttttttg
     1921 tatgtggaat ttgtcccatg tgcttgctaa aatgtttggg gatctcctca cactggtaat
     1981 gtctttcctg ttagagaggt ttatgctacc acttcgcatt tcatctgtga ggcatttcat
     2041 cttttagata tgtcttcatg tccagctact tgtttcacca tggcagacct ccctgagtct
     2101 tcttcctgcc ctgggtagga agtgtggctc tgggtctgtg gtcactctcc accttgtcct
     2161 agtgttgcca tggtagcatg gctttgtagt ttgcatttaa cctggggatc tatgcatcct
     2221 gtcaagaggg tgggtccccg tccccgtgtg tggaaaagag acagtgtggc ttgctgccag
     2281 gctcaggcca ggtctggaca gctctcactc tcctcaagcc aggactaccg accagccggc
     2341 tatgggcaca ttactctgtg gctgctggat tcttttccag catgcctgtg gcctgtgtga
     2401 ggcagaactg ggacccttga ttcccagatt gggagtcagc caaggacact ggggctgaat
     2461 gaaatgccca ttcttcaggc atttctacca taatattgga attgaacaca ttggctaaat
     2521 aaagttgaaa ttttact
//