Newsgroups: bionet.molbio.genbank.updates
Subject: Human major histocompatibility class II antigen gamma chain mRNA,
From: GenBank-Updates@net.bio.net
Date: 6 Nov 92 18:29:56 GMT
Distribution: bionet
Checksum: 21072 4

LOCUS       HUMMHGM      1287 bp ss-mRNA            PRI       02-NOV-1992
DEFINITION  Human major histocompatibility class II antigen gamma chain mRNA,
            complete cds.
ACCESSION   K01144
KEYWORDS    antigen; histocompatibility antigen.
SOURCE      Human cDNA to mRNA, clone p-gamma-2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1287)
  AUTHORS   Claesson,L., Larhammar,D.G., Rask,L. and Peterson,P.A.
  TITLE     cDNA clone for the human invariant gamma chain of class II
            histocompatibility antigens and its implications for the protein
            structure
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 80, 7395-7399 (1983)
  STANDARD  full automatic
COMMENT     There is another initiation codon located 45 bp upstream of the
            gamma chain start (see sites table). The authors [1] think that
            this may be due to a 28 bp inverted repeat of the 3' end of the
            sequence.
FEATURES             Location/Qualifiers
     mRNA            <1..>1287
                     /note="gamma chain mRNA"
     CDS             100..750
                     /product="class II antigen gamma chain"
                     /codon_start=1
                     /translation="MDDQRDLISNNEQLPMLGRRPGAPESKCSRGALYTGFSILVTLL
                     LAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQAL
                     PMGALPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKGSFPENLRHLKNTMETI
                     DWKVFESWMHHWLLFEMSRHSLEQKPTDAPPKESLELEDPSSGLGVTKQDLGPVPM"
BASE COUNT      287 a    438 c    338 g    224 t
ORIGIN      156 bp upstream from NarI site
        1 ctgcaggggg gggggggggg gggggggaca ttggctcttc cttggggagt gatgcacagg
       61 aggagaagca ggagctgtcg ggaagatcag aagccagtca tggatgacca gcgcgacctt
      121 atctccaaca atgagcaact gcccatgctg ggccggcgcc ctggggcccc ggagagcaag
      181 tgcagccgcg gagccctgta cacaggcttt tccatcctgg tgactctgct cctcgctggc
      241 caggccacca ccgcctactt cctgtaccag cagcagggcc ggctggacaa actgacagtc
      301 acctcccaga acctgcagct ggagaacctg cgcatgaagc ttcccaagcc tcccaagcct
      361 gtgagcaaga tgcgcatggc caccccgctg ctgatgcagg cgctgcccat gggagccctg
      421 ccccaggggc ccatgcagaa tgccaccaag tatggcaaca tgacagagga ccatgtgatg
      481 cacctgctcc agaatgctga ccccctgaag gtgtacccgc cactgaaggg gagcttcccg
      541 gagaacctga gacaccttaa gaacaccatg gagaccatag actggaaggt ctttgagagc
      601 tggatgcacc attggctcct gtttgaaatg agcaggcact ccttggagca aaagcccact
      661 gacgctccac cgaaagagtc actggaactg gaggacccgt cttctgggct gggtgtgacc
      721 aagcaggatc tgggcccagt ccccatgtga gagcagcaga ggcggtcttc aacatcctgc
      781 cagccccaca cagctacagc tttcttgctc ccttcagccc ccagcccctc ccccatctcc
      841 caccctgtac ctcatcccat gagaccctgg tgcctggctc tttcgtcacc cttggacaag
      901 acaaaccaag tcggaacagc agataacaat gcagcaaggc cctgctgccc aatctccatc
      961 tgtcaacagg ggcgtgaggt cccaggaagt ggccaaaagc tagacagatc cccgttcctg
     1021 acatcacagc agcctccaac acaaggctcc aagacctagg ctcatggacg agatgggaag
     1081 gcacagggag aagggataac cctacaccca gaccccaggc tggacatgct gactgtcctc
     1141 tcccctccag cctttggcct tggcttttct agcctattta cctgcaggct gagccactct
     1201 cttccctttc cccagcatca ctccccaagg aagagccaat gttttccacc catccctccc
     1261 cccccccccc cccccccccc cctgcag
//