From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Candida tropicalis aspartic proteinase (ACP) gene, complete cds.
Date: 7 Apr 92 10:06:53 GMT
Distribution: bionet
Checksum: 41158     5

LOCUS       YSAACP       1804 bp ds-DNA             PLN       07-APR-1992
DEFINITION  Candida tropicalis aspartic proteinase (ACP) gene, complete cds.
ACCESSION   X61438 M76126
KEYWORDS    acid protease.
SOURCE      Candida tropicalis DNA.
  ORGANISM  Candida tropicalis
            Eukaryota; Fungi; Eumycota; Deuteromycotina.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Togni,G., Sanglard,D., Falchetto,R. and Monod,M.
  TITLE     Isolation and nucleotide sequence of the extracellular acid
            protease gene (ACP) from the yeast Candida tropicalis
  JOURNAL   FEBS Lett. 286, 181-185 (1991)
  STANDARD  full automatic
COMMENT     *source: strain=ATCC750; *source: clone_library=genomic library in
            lambda DashII; *source: is_macronuclear=N; *source: is_proviral=N;
            *source: is_germline=N;
            From EMBL    entry CTACP;  dated 30-AUG-1991.
            Submitted (20-AUG-1991) on tape to the EMBL Data Library
            by: D. Sanglard, Swiss Federal Inst of Technology,
            Institute of Biotechnology, ETH-Hoenggerberg HPT D71,
            Zuerich 8093, SWITZERLAND
FEATURES             Location/Qualifiers
     TATA_signal     146..151
                     /number=1
                     /note="putative"
                     /gene="ACP"
     TATA_signal     165..171
                     /number=2
                     /note="putative"
                     /gene="ACP"
     TATA_signal     369..375
                     /number=3
                     /note="putative"
                     /gene="ACP"
     sig_peptide     457..636
                     /note="ends with Lys-Arg peptidase cleavage site"
                     /gene="ACP"
     CDS             457..1641
                     /EC_number="3.4.23.6"
                     /note="pro-product"
                     /product="aspartic proteinase"
                     /gene="ACP"
                     /translation="MATIFLFTKNVFIALAFALFAQGLTIPDGIEKRTDKVVSLDFTV
                     IRKPFNATAHRLIQKRSDVPTTLINEGPSYAADIVVGSNQQKQTVVIDTGSSDLWVVD
                     TDAECQVTYSGQTNNFCKQEGTFDPSSSSSAQNLNQDFSIEYGDLTSSQGSFYKDTVG
                     FGGISIKNQQFADVTTTSVDQGIMGIGFTAVEAGYNLYSNVPVTLKKQGIINKNAYSC
                     DLNSEDASTGKIIFGGVDNAKYTGTLTALPVTSSVELRVHLGSINFDGTSVSTNADVV
                     LDSGTTITYFSQSTADKFARIVGATWDSRNEIYRLPSCDLSGDAVVNFDQGVKITVPL
                     SELILKDSDSSICYFGISRNDANILGDNFLRRAYIVYDLDDKTISLAQVKYTSSSDIS
                     AL"
     mat_peptide     637..1638
                     /EC_number="3.4.23.6"
                     /note="mature product"
                     /product="aspartic proteinase"
                     /gene="ACP"
BASE COUNT      518 a    314 c    330 g    642 t
ORIGIN
        1 aagctttatc ttgagtatat tcgtacatta aacatttctc cacgctccaa attgatggtg
       61 ctgtgcctta ccagattttt tttatcattt agaatgcaga tctcctgtat ttgaaattct
      121 ttggattttt ttcaacaaaa cggattatat aattaacgtt catgtataaa atgttaaata
      181 atctgagttt tagtttatgc tttcattgtt tttctttttg acgataagct aaccttgata
      241 tcaaaactag aaccacaatt attcaagtat tgcccataga aatgaacggc tccacttttt
      301 tgttgttatt gtagatggag gactaggagg tgacggaatt aatgaaaaag gaagtcaaag
      361 taaagtaata taaataccca tgtcccaatc atatttcaag gttggatttg gttctaattt
      421 ttattccatt attaactact attactatca caaaaaatgg ctaccatttt cttattcact
      481 aaaaacgttt ttattgctct tgcttttgct ttgtttgctc aaggtcttac tatcccagat
      541 ggtattgaga aaagaaccga caaggttgtt tctttggatt ttactgttat tagaaaaccg
      601 ttcaatgcca ctgctcatag gctcattcaa aagagaagtg atgtgccaac tacattgatc
      661 aatgagggtc catcatatgc tgctgatatt gttgttggtt ccaaccaaca aaagcaaact
      721 gttgtcattg acaccggttc ttctgatttg tgggttgttg ataccgatgc cgagtgccaa
      781 gttacttact ctggacaaac caacaatttt tgcaaacaag aaggaacctt tgatccatct
      841 tcttctagtt ctgctcaaaa cttgaaccaa gatttctcca ttgagtatgg agacttgact
      901 tcgtctcaag gtagttttta caaagacacc gttggttttg gaggtatttc tattaagaat
      961 caacaatttg ctgatgtcac tacaacttct gttgatcaag gtatcatggg gattggtttc
     1021 actgctgtag aagctggata caatctgtat agcaatgtgc cagttacttt gaagaaacaa
     1081 ggtatcatca acaagaatgc ctattcttgt gacttgaact ctgaagatgc ttctactggt
     1141 aagatcatct ttggcggtgt tgataatgcc aaatataccg ggactttgac tgctttacct
     1201 gtgacttcat cagttgaatt aagagttcat ttgggttcca ttaattttga cggaacaagc
     1261 gtttctacca acgctgatgt tgttttggac tctggtacca caattacata cttttcgcaa
     1321 agtactgctg acaagtttgc tagaattgtc ggggccactt gggatagcag aaacgaaatt
     1381 taccgtttgc cttcatgtga cctttctggt gacgcagttg tcaactttga tcaaggtgtt
     1441 aaaattactg ttcccctttc cgaattgatt cttaaagaca gtgacagctc aatttgctat
     1501 tttggaattt ccagaaatga tgctaacatt ttgggagata atttcttaag aagagcttat
     1561 attgtgtatg atttggacga taagaccatt tccttggctc aagtcaagta cacttcttct
     1621 tcagacatct cggctttgta gaaagtataa ttgaatttat tcggtatatt tagtttatct
     1681 tgagtcgttc tgtaattctt cactttgaca tttttcccga atatgtattg aagtatgaaa
     1741 gtaatataga tatatacacg gttcgtttga tattgtcatt atagacatcc atctaaagga
     1801 attc
//