From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Drosophila melanogaster (strain Oregon R) ecdysone-inducible
Date: 7 Jan 93 05:46:08 GMT
Distribution: bionet
Checksum: 33415 5

LOCUS       DROECDINME   1232 bp ds-DNA             INV       06-JAN-1993
DEFINITION  Drosophila melanogaster (strain Oregon R) ecdysone-inducible
            membrane (IMP-L1) gene, complete cds.
ACCESSION   M97259
KEYWORDS    ecdysone-inducible membrane; secreted protein.
SOURCE      Drosophila melanogaster (strain Oregon R) prepupal imaginal disc
            (mass culture) DNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Natzle,J.E., Fristrom,D.K. and Fristrom,J.W.
  TITLE     Isolation of genes active during hormone-induced morphogenesis in
            Drosophila imaginal discs
  JOURNAL   J. Biol. Chem. 261, 5575-5583 (1986)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1232)
  AUTHORS   Natzle,J.E., Robertson,J.P., Majumdar,A., Vesenka,G.D., Enlow,B.
            and Clark,K.E.
  TITLE     Sequence and expression of IMP-L1, an ecdysone-inducible gene
            expressed during Drosophila imaginal disc morphogenesis
  JOURNAL   Dev. Genet. 13, 331-344 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     join(36..66,141..184)
                     /gene="IMP-L1"
                     /label=signalpeptide
                     /codon_start=1
     5'UTR           1..35
                     /gene="IMP-L1"
                     /label=UTR5'
     exon            1..66
                     /gene="IMP-L1"
                     /label=exon1
     intron          67..140
                     /gene="IMP-L1"
                     /label=intron1
     exon            141..1232
                     /gene="IMP-L1"
                     /label=exon2
     3'UTR           1136..1232
                     /gene="IMP-L1"
                     /label=UTR3'
     misc_signal     1172..1185
                     /gene="IMP-L1"
                     /note="'motif associated with rapid mRNA turnover'"
     polyA_signal    1195..1200
                     /gene="IMP-L1"
     CDS             join(36..66,141..1135)
                     /standard_name="secreted protein"
                     /gene="IMP-L1"
                     /product="ecdysone-inducible membrane"
                     /codon_start=1
                     /translation="MRPYQVVCIVAVAALLLLEAIPADAKRRKHKGSDHHYEKSDPHK
                     TKTKTKWSSSTDLAGNTPISTEEHGYYVKRTFAAPGEIGAAQKRLSPPYLAIPIAWFS
                     CESGQKNCQSSNSAAINSAAQSLSEGYLCDDDCDELYEPICGRTSSEVAVFYNKCKLG
                     VAKCRSHGLWTDFAYAECQAKYPQETAYADKKFRSSPYFRDAAIVEQLKLEEEKRKQE
                     EEQHKLEKEQKKKEKAEKNKNEKDSSESSEEKDDQKENKQKDPLSLMPQKKVESTQKP
                     VPVPIQVAVPKPVSVLEPAKTTEDIAMPPMPLKDTPTPKPLEIAPLHQQTQPKGKDID
                     RLKYQVA"
BASE COUNT      361 a    312 c    309 g    250 t
ORIGIN      
        1 agttgttgtg gagtcgagca gctgaccaga tcaacatgag gccataccaa gtagtttgca
       61 tcgtaggtaa gtctcgcata tcgaagctga ccagttctgg aagtcccata attaactggt
      121 atgcgcccat ttccttttag cagtagcagc tctgctgctt ttggaggcga ttcccgcgga
      181 tgcaaagcgg cgcaagcaca agggctccga tcatcactat gaaaagtctg atccccacaa
      241 gaccaagaca aagaccaagt ggtctagctc cacggatttg gctggaaaca ctccaatttc
      301 caccgaagag cacggctact atgtaaagcg cacctttgcg gctcccggtg agattggagc
      361 cgcacagaag cgtctaagtc ccccctattt ggccattccc atcgcctggt tcagctgtga
      421 gtcgggccag aagaattgcc agtcttccaa ttccgcggct atcaacagtg ccgcgcagtc
      481 cttgagcgag ggctatctgt gcgacgatga ttgcgatgaa ctgtatgagc ccatctgcgg
      541 caggacctcc tcagaggtgg ccgttttcta caacaagtgc aagttgggtg tagccaagtg
      601 ccgatcccac ggtctttgga cggacttcgc ctatgccgag tgccaggcga aatatccgca
      661 ggaaactgcc tatgccgaca agaagttccg gtcatcgcct tatttccggg atgcggccat
      721 cgtggagcaa ttgaagctgg aggaggagaa gcgtaagcag gaggaggaac aacacaagct
      781 ggagaaggag caaaagaaga aggagaaggc tgagaaaaat aagaacgaga aggacagcag
      841 cgaaagcagc gaggagaagg atgaccaaaa ggaaaacaag cagaaggatc ccctttccct
      901 aatgccacag aagaaagtgg aatccaccca gaagccagtg ccagttccta ttcaagtagc
      961 agttccaaaa ccagtttcag ttttggagcc tgcaaagacg accgaggaca tcgctatgcc
     1021 gcctatgcca ctgaaggaca ctcccacgcc caaacctctg gagatcgcgc cccttcacca
     1081 gcagacccaa cccaagggca aggacattga taggctcaag taccaagtag cttagaaagc
     1141 aatggctaca caaatctcac ctaattatag tatttattta atttattaca aacaaataaa
     1201 attctaaaca acgataatca tctatatttg at
//