HDTenEightyP/NetNews huggingface dataset:
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.announce
Subject: CALL FOR DISCUSSION: BNFNET-L transfer to BIOSCI.
Date: 27 Jan 93 23:44:42 GMT
Distribution: bionet

We have received a proposal to assume adminstrative responsibility for
an existing mailing list called BNFNET-L.  The current list maintainer
will retain his position as discussion leader of BNFNET-L.

Proposed USENET name: bionet.biology.n2-fixation
E-mail address: BNFNET-L

Discussion will now be open through 7 February on
BIOFORUM/bionet.general (*not* on BIONEWS/bionet.announce).

Please do not post one-line messages saying only "I am in favor of
such a newsgroup".  We will collect votes later.  The discussion
period is an opportunity for anyone to bring up reservations about the
proposed charter and to propose modifications prior to the vote.  The
discussion leader may submit a revised proposal in light of the
discussion, and the new charter would be included in the call for votes
which will go out on 8 February.

Please be aware that only one vote is counted per e-mail address, so
it is necessary to have your own account in order to vote.  Multiple
votes from the same address are not accepted.  If you are interested
in the following newsgroup, but do not have an e-mail address of your
own, please obtain one from your computer center before the call for
votes is issued.

----------------------------------------------------------------------
Proposal to establish BNFNET-L/bionet.biology.n2-fixation

Discussion leader:  Eng-leong Foo
                    Director, Unesco Microbial Resources Center
                    Karolinska Institute, 10401 Stockholm, Sweden
                    Phone: 46-8-7287145    Fax: 46-8-331547
                    email: eng-leong_foo_mircen-ki%micforum@mica.mic.ki.se

BNFNET-L aims
(a) to provide a forum for the exchange of information and
    discussions on scientific research, activities and
    experiences on biological nitrogen fixation.
(b) to serve as a bulletin board for announcements of forthcoming
    conferences, reviews of publications, profiles of
    organizations, etc.
(c) to act as the general list for the Biological Nitrogen
    Fixation Electronic Network.

Biological Nitrogen Fixation Electronic Network (BNFNET) was
established in 1990 by UNESCO's MIRCEN (Microbial Resources
Center) Network for Environmental, Applied Microbiological and
Biotechnological Research. BNFNET aims to (i) foster better
communication and cooperation among MIRCENs and between MIRCENs
and other organizations, (ii) encourage and help laboratories and
individuals to use e-mail for communications in BNF (iii) help
researchers to identify resources of culture collections.
----------------------------------------------------------------------
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.announce
Subject: BIOSCI at net.bio.net offline this Saturday!
Date: 26 Jan 93 21:04:02 GMT
Distribution: bionet
Organization: BIOSCI International Newsgroups for Biology

* Notice * Notice * Notice * Notice * Notice * Notice * Notice *
*                                                              *
*    All IntelliGenetics fileservers will be down from 2pm     *
*    until midnight on January 25, the last Saturday of this   *
*    month, for semiannual permanent full backup.  All of      *
*    our shared computers will be unusable during this time.   *
*                                                              *
* Notice * Notice * Notice * Notice * Notice * Notice * Notice *

This means that the BIOSCI node at net.bio.net will be offline during
this time.  Mail will be queued until the system comes back on-line.
News distribution will also resume then and no messages should be
lost.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				kristoff@net.bio.net
From: kristoff@net.bio.net (David Kristofferson)
Newsgroups: bionet.announce
Subject: Re: BIOSCI at net.bio.net offline this Saturday!
Date: 26 Jan 93 21:09:37 GMT
Distribution: bionet
Organization: BIOSCI International Newsgroups for Biology

Sorry!  The downtime notice had an error in it.  Next Saturday is
obviously the 30th!


Newsgroups: bionet.neuroscience
From: cohen@cmu.unige.ch
Subject: Looking: stereotaxic atlas mouse brain
Organization: University of Geneva, Switzerland
Date: Mon, 25 Jan 1993 09:21:05 GMT

Which and where can I find a good stereotaxic atlas of the mouse
brain ?
Thanks,

Emmanuel-S. Cohen-Laroque
Dept of Pathology
Unviersity of Geneva
Switzerland
From: reynolds@park.bu.edu (John Reynolds)
Newsgroups: bionet.neuroscience
Subject: urgent request
Date: 29 Jan 93 00:18:06 GMT
Distribution: bionet.neuroscience
Organization: Boston University Center for Adaptive Systems


To anyone who can help,

I am writing from Vancouver, where my wife and I are trying
to help family friends whose son was in a severe car accident.  I
am writing in the hope that you may be able to give me some idea 
about what sorts of questions I should be asking the doctor in charge,
or possibly give me the name of a neurosurgeon who could give us help 
or advice.

The patient was admitted to Vancouver General hospital Saturday night with 
shear brain hemorrhaging and a "basal" skull fracture.    The damage
appears to be diffuse, affecting many areas of the brain.  He 
described it as the worst head injury they have had in the hopital.
The doctor tells us that CAT scans have revealed
that the hemorrhaging has stopped.  However, the brain is swollen, and
the doctor has been draining fluid to keep the swelling as low as 
possible.  One thing that concerns me is that I have heard that it 
is common to use steroids to keep brain swelling down, especially 
immediately after a trauma, when swelling causes great damage.  The
doctor in charge told me that no steroids were used, and that they
are typically only used for chronic swelling.  He says that the patient
is not in mortal danger, but that the likelihood of his ever regaining
conciousness is very slim.

As you can understand, the parents, who speak no English (they are 
from Taiwan), are terrified, and I have to do anything I can to 
see that their son gets the best treatment possible, and that 
I am able to keep them informed as best I can.  Any advice you can 
offer would be deeply appreciated.  I will check my email frequently.  

Sincerely, John Reynolds
From: anderson@CSHL.ORG (John Anderson)
Newsgroups: bionet.neuroscience
Subject: SNNS simulator
Date: 21 Jan 93 19:30:46 GMT
Distribution: bionet

>   I have obtained the SNNS (Stuttgart Neural Net Simulator) from 
>   Stuttgart University via anon ftp and compiled it on an IBM RS6000

What is the Stuttgart Neural Net Simulator?  How does it compare with,
e.g., GENESIS?

Thanks

John
-------
John E. Anderson
W. M. Keck Structural Biology Laboratory
Cold Spring Harbor Laboratory
From: oivind@pons.uio.no
Newsgroups: bionet.neuroscience
Subject: Temperature gradient in rat brain
Date: 28 Jan 93 12:27:00 GMT
Reply-To: oivind@pons.uio.no
Organization: Universitetet i Oslo


 Hi there!
I am a grad student at the University of Oslo and I am working on synaptic
mechanisms of learning and memory.
 Does anybody know about publications/results about temperature gradients in
rat brain in the awake and/or anesthetized state? Any pointers would be 
appreciated!

Iacob Mathiesen
From: anderson@CSHL.ORG (John Anderson)
Newsgroups: bionet.neuroscience
Subject: primary afferent depolarization
Date: 25 Jan 93 12:54:59 GMT
Distribution: bionet

I have been reading 

  Sykova E. (1991) "Activity-related ionic and volume changes in
  neuronal microenvironment" in _Volume Transmission in the Brain_ (K.
  Fuxe, L.F. Agnati, Eds.), pp 317-336, Raven Press, New York.

In that article, the following statement is made:

  "[Extracellular] K+ accumulation has been accepted as one of two
  causal factors (together with GABA) in primary afferent
  depolarization, which is the mechanism underlying presynaptic
  inhibition.  It is assumed that the increase in [K+]e that is
  associated with repetitive neuronal activity reduces transmitter
  release by curtailing the presynaptic spike amplitude by presynaptic
  depolarization."

Could someone please explain this statement?  How does presynaptic
depolarization reduce the presynaptic spike amplitude?  Seems like it
should enhance it.

Please reply to the neuroscience@net.bio.net list or email me
directly, as my site doesn't receive every bionet.neuroscience posting
for some reason.

Thanks

John
-------
John E. Anderson
W. M. Keck Structural Biology Laboratory
Cold Spring Harbor Laboratory
From: falex@coue.loria.fr (Frederic Alexandre)
Newsgroups: bionet.neuroscience
Subject: Re: Neural Columns
Date: 25 Jan 93 13:55:34 GMT
Organization: Crin-Inria-Lorraine

We have been working for 6 years on a modelization of the cortical
column as a basic unit of connectionist networks. The basic idea is to
define a functional micro-circuit of neurons (cortical column) as
a basic unit with specific input/output, learning and functioning 
rules. These rules and architecture have been defined with
neurobiological consideration.

From a computer science point of view, we have applied this model
to speech processing, image interpretation and robotics.

If you are interested, you may have a look to:

Alexandre, F., Burnod, Y., Guyot, F., Haton, J.P. (1991) "The
  Cortical Column: a new processing unit for multilayered networks",
  Neural Networks, Vol 4, n 1, pp. 15-25, 1991. 

Guyot, F., Alexandre, F., Haton, J.P. (1990) "Principles and
 applications of the cortical column symbolic neural model", IJCNN'90,
 San Diego. 

Alexandre, F., Guyot, F., Haton, J.P. (1990) "A connectionist
network with two complementary visual processing systems for x-ray
image interpretation", INNC'90, Paris.
 
I hope this can help

 alex

E-mail: falex@loria.fr
From: jxj24@po.CWRU.Edu (Jonathan Jacobs)
Newsgroups: bionet.neuroscience
Subject: Re: Biofeedback and Attention Deficit Disorder
Date: 23 Jan 1993 05:02:57 GMT
Organization: Case Western Reserve University, Cleveland, OH (USA)
Reply-To: jxj24@po.CWRU.Edu (Jonathan Jacobs)
NNTP-Posting-Host: slc12.ins.cwru.edu


In a previous article, ah190@cleveland.Freenet.Edu (Stuart Pearl) says:

>
>Does anyone know if biofeedback techniques can be used in treating
>attention deficit disorders (ADD)?  Has there been any research done
>in this area?  Thanks.
>
>-stu
>-- 
>                   ---===<<< Stuart Pearl >>>===---
>                           Cleveland, Ohio
>                      ah190@cleveland.freenet.edu
>                         --------------------
>

That's a good question.  I may just try to find an answer, as I am
blessed with ADD.  I was not formally diagnosed until I was 26, however.
I guess I have a comparatively milder manifestation of it than many, however.
Believe it or not, in the past few years, studies have shown that even
adults can benefit from Ritalin.  You can find an article in Am-J-Psych
of May '85, if you are interested, but it is pretty dry reading.

On a less scientific note, subjectively I think that Ritalin, when it works,
is amazing.  I have a couple of _minor_ side effects and find that the 
optimal dose varies with many factors such as phase of moon.  But it is
very definitely worth it.  But it would be even better if other techniques
can be employed in conjunction to reduce the need for the drug.

Jon Jacobs
Dept. of Biomedical Engineeeeeeeering
Case Western Reserve University
Right in your back yard.
From: jxj24@po.CWRU.Edu (Jonathan Jacobs)
Newsgroups: bionet.neuroscience
Subject: Re: Schizophrenia and the immune system
Date: 23 Jan 1993 04:52:03 GMT
Organization: Case Western Reserve University, Cleveland, OH (USA)
Reply-To: jxj24@po.CWRU.Edu (Jonathan Jacobs)
NNTP-Posting-Host: slc12.ins.cwru.edu


In a previous article, mitchm@casbah.acns.nwu.edu (Mitchell Maltenfort) says:

>
>	I was recently watching a PBS "Frontline" on schizophrenia, and was
>struck by an idea when it was mentioned that schizophrenics have certain
>white blood cell abnormalities.  Is it possible that schizophrenia is an
>autoimmune disease?
>
>	There is some precedent for this: myasthenia gravis is an autoimmune
>disease in which the immune system targets the neurotransmitters that activate
>muscle.  Might schizophrenia be the result of the immune system interfering
>with the brain functions? 
>
>	Although I have some basic knowledge of the nervous system, I don't
>know as much about the specific condition of schizophrenia or the immune
>system as I should to be able to evaluate this possibility.  I'm just posting
>it to get some discussion going.  
>
>
>Mitchell Maltenfort	Northwestern Unversity	Chicago, Illinois
>
>mgm@nwu.edu		|:* Studying simulations or simulating studies *:|
>
>
Mitchell,

Not to be pedantic, but in myasthenia gravis the _receptors_ for the 
neurotransmitter (acetylcholine) are attacked by the immune system, not
the neurotransmitter itself.

But it is an interesting question alright.  It certainly seems plausible
enough, and god knows that there are about a zillion ways your immune
system can turn on you when you least expect it.  And there are about
a zillion more ways that your brain can unravel on you when you least 
realize it.  Actually, that sounds very depressing when I reread it, but
it's absolutely fantastic how something so complex as an entire organism
can actually exist.  Even when it doesn't work quite right.

Just remember: "It's not how well the bear dances, but that it dances at all."

Jon Jacobs
Dept. of Biomedical Engineerin' and stuff
Case Western Reserve University
Accept no substitutes.
Newsgroups: bionet.neuroscience
From: knowled@ccsmtp.ccf.org (Doug Knowles)
Subject: Re: Looking: stereotaxic atlas mouse brain
Organization: Cleveland Clinic Foundation
Date: Mon, 25 Jan 1993 16:01:36 GMT

In article <1993Jan25.112105.1@cmu.unige.ch> cohen@cmu.unige.ch writes:
>From: cohen@cmu.unige.ch
>Subject: Looking: stereotaxic atlas mouse brain
>Date: Mon, 25 Jan 1993 09:21:05 GMT
>Which and where can I find a good stereotaxic atlas of the mouse
>brain ?
>Thanks,
>
>Emmanuel-S. Cohen-Laroque
>Dept of Pathology
>Unviersity of Geneva
>Switzerland
>

A Stereotaxic Atlas of the Albino Mouse Forebrain
Burton M. Slotnick and Christiana M. Leonard 1975
US Department of Health, Education, and Welfare 
                 Publication Number (ADM) 75-100
Out of Print, but a few copies may be available from the second
author, C.M. Leonard, at University of Florida Center for Neurobiological
Sciences, Box J244, J.H.M. Health Center, Gainsville, Florida 32610.


Atlas of the Mouse Brain and Spinal Cord
Richard L. Sidman, Jay B. Angevine, Elizabeth Taber Peirce 1971
Harvard University Press, Cambridge, Massachusetts
Not Stereotaxic, but a nice atlas.

W. Douglas Knowles, Ph.D.      knowled@ccsmtp.ccf.org
Cleveland Clinic Foundation
9500 Euclid Ave., Cleveland, OH
W. Douglas Knowles, Ph.D.            E-mail: knowled@ccsmtp.ri.ccf.org
Department of Neurosciences          voice:  (216) 444-3870
Cleveland Clinic Foundation          FAX:    (216) 444-7927
9500 Euclid Avenue                   
Cleveland, OH 44195 USA              other:   hey, you!
 
quote: "We need not all give our whole time to the currently more glamorous
"molecular biology"; it will doubtless come soon enough."  I.H. Page 1962
   
Newsgroups: bionet.neuroscience
From: knowled@ccsmtp.ccf.org (Doug Knowles)
Subject: Re: primary afferent depolarization
Organization: Cleveland Clinic Foundation
Distribution: bionet
Date: Mon, 25 Jan 1993 16:52:34 GMT

In article <9301251254.AA21883@xray1.cshl.org> anderson@CSHL.ORG (John Anderson) writes:
>From: anderson@CSHL.ORG (John Anderson)
>Subject: primary afferent depolarization
>Date: 25 Jan 93 12:54:59 GMT
> 
....
 
>Could someone please explain this statement?  How does presynaptic
>depolarization reduce the presynaptic spike amplitude?  Seems like it
>should enhance it.
>
>-------
>John E. Anderson
>W. M. Keck Structural Biology Laboratory
>Cold Spring Harbor Laboratory


The amount of transmitter released is dependent on the amount of
calcium which enters the presynaptic terminal, which is dependent 
on the amplitude of the action potential in the presynaptic
terminal.  Prior depolarization of the terminal (e.g. by inceased
extracellular K+) reduces the difference between the (depolarized)
resting potential and the peak of the action potential, thus 
reducing the action potential amplitude.  This causes less calcium
entry, less transmitter release, and a smaller postsynaptic 
potential.

I'm not sure why the calcium entry is dependent on the amplitude
of the action potential, rather than absolute membrane potential
difference.  Probably because of the time and voltage dependence
of the calcium channels.  I'll have to defer to my more informed
biophysics colleagues  (Bill?).

W. Douglas Knowles, Ph.D.            E-mail: knowled@ccsmtp.ri.ccf.org
Department of Neurosciences          voice:  (216) 444-3870
Cleveland Clinic Foundation          FAX:    (216) 444-7927
9500 Euclid Avenue                   
Cleveland, OH 44195 USA              other:   hey, you!
 
quote: "We need not all give our whole time to the currently more glamorous
"molecular biology"; it will doubtless come soon enough."  I.H. Page 1962
   
Newsgroups: bionet.neuroscience,comp.sys.mac.misc,sci.psychology
From: davis@pacific.mps.ohio-state.edu ("John E. Davis")
Subject: MACs for psychophysics
Reply-To: davis@pacific.mps.ohio-state.edu  (John E. Davis)
Organization: "Dept. of Physics, The Ohio State University"
Date: Mon, 25 Jan 1993 03:17:10 GMT


I am posting this for a friend.  I have no idea of the proper group in which
to post this article. 

                        ------------------------------
Our laboratory is interested using a Mac to display simple and complex 
images as stimuli in human psychophysical experimentation.  We would need 
control of the timing and need synch pulses to control auxiliary equipment. 
 Is anyone aware of commercial hardware/software packages to do this?  
Please respond directly to duffyfr@a1.tch.harvard.edu.  Thank you.
Frank H. Duffy




--
     _____________
#___/John E. Davis\_________________________________________________________
#
# internet: davis@amy.tch.harvard.edu
#   bitnet: davis@ohstpy
#   office: 617-735-6746
#
From: hurh@fnal.fnal.gov (Patrick Hurh)
Newsgroups: bionet.neuroscience
Subject: Re: MACs for psychophysics
Date: 25 Jan 93 18:34:56 GMT
Followup-To: bionet.neuroscience,comp.sys.mac.misc,sci.psychology
Organization: fnal

In article <DAVIS.93Jan24221710@pacific.mps.ohio-state.edu>,
davis@pacific.mps.ohio-state.edu ("John E. Davis") wrote:
> 
> 
> I am posting this for a friend.  I have no idea of the proper group in which
> to post this article. 
> 
>                         ------------------------------
> Our laboratory is interested using a Mac to display simple and complex 
> images as stimuli in human psychophysical experimentation.  We would need 
> control of the timing and need synch pulses to control auxiliary equipment. 
>  Is anyone aware of commercial hardware/software packages to do this?  
> Please respond directly to duffyfr@a1.tch.harvard.edu.  Thank you.
> Frank H. Duffy
> 
> 

Not sure if this would work for your app, but a project I design for uses
LabView to display and analyze synchrotron light (from protons ie ultra
violet) plus send pulses to stepper motors and the like.  It is a very
flexible package which you program yourself to interact through NuBus
boards to your various pieces of equipment.
> 
> 
> --
>      _____________
> #___/John E. Davis\_________________________________________________________
> #
> # internet: davis@amy.tch.harvard.edu
> #   bitnet: davis@ohstpy
> #   office: 617-735-6746
> #

Patrick      HURH@FNAL.FNAL.GOV
From: anderson@CSHL.ORG (John Anderson)
Newsgroups: bionet.neuroscience
Subject: primary afferent depolarization
Date: 25 Jan 93 21:36:23 GMT
Distribution: bionet

>   From: knowled@ccsmtp.ccf.org (Doug Knowles)
>   Date: 25 Jan 93 16:52:34 GMT
>
>   The amount of transmitter released is dependent on the amount of
>   calcium which enters the presynaptic terminal, which is dependent 
>   on the amplitude of the action potential in the presynaptic
>   terminal.  Prior depolarization of the terminal (e.g. by inceased
>   extracellular K+) reduces the difference between the (depolarized)
>   resting potential and the peak of the action potential, thus 
>   reducing the action potential amplitude.  This causes less calcium
>   entry, less transmitter release, and a smaller postsynaptic 
>   potential.
>
>   I'm not sure why the calcium entry is dependent on the amplitude
>   of the action potential, rather than absolute membrane potential
>   difference.  

This is exactly what bothers me.

>Probably because of the time and voltage dependence
>   of the calcium channels.  I'll have to defer to my more informed
>   biophysics colleagues  (Bill?).

Does anybody know?

Thanks

John
-------
John E. Anderson
W. M. Keck Structural Biology Laboratory
Cold Spring Harbor Laboratory
From: wcalvin@stein.u.washington.edu (William Calvin)
Newsgroups: bionet.neuroscience
Subject: Re: primary afferent depolarization
Date: 25 Jan 93 17:10:40 GMT
Distribution: bionet
Organization: University of Washington
NNTP-Posting-Host: stein.u.washington.edu

anderson@CSHL.ORG (John Anderson) writes:

>I have been reading 
>  Sykova E. (1991) "Activity-related ionic and volume changes in
>  neuronal microenvironment" in _Volume Transmission in the Brain_ (K.
>  Fuxe, L.F. Agnati, Eds.), pp 317-336, Raven Press, New York.
>In that article, the following statement is made:
>  "[Extracellular] K+ accumulation has been accepted as one of two
>  causal factors (together with GABA) in primary afferent
>  depolarization, which is the mechanism underlying presynaptic
>  inhibition.  It is assumed that the increase in [K+]e that is
>  associated with repetitive neuronal activity reduces transmitter
>  release by curtailing the presynaptic spike amplitude by presynaptic
>  depolarization."

>Could someone please explain this statement?  How does presynaptic
>depolarization reduce the presynaptic spike amplitude?  Seems like it
>should enhance it.

Repetitive activation of neurons dumps some K outside the cell; like a
local hormone, it *may* reduce membrane potentials of other neurons.  What
this does to transmitter release by spikes depends on accomodation-like
factors such as sodium inactivation and such.  The invading spike may stop
*actively* propagating upstream and only passively invade the terminal, so
that the spike height stimulating transmitter release is smaller.
There are other factors as well, both on that hypothesis and on other
causes of presynaptic inhibition.
    William H. Calvin   WCalvin@U.Washington.edu
    University of Washington  NJ-15
    Seattle, Washington 98195 FAX:1-206-720-1989
Xref: sparky bionet.neuroscience:703 comp.ai.neural-nets:5011
From: Shiv Kaul
Newsgroups: bionet.neuroscience,comp.ai.neural-nets
Subject: Re: glitches compiling SNNS on RS6000
Date: 28 Jan 93 17:29:24 GMT
Organization: Bloomsbury Computing Consortium
Organisation: University College London

mitchm@casbah.acns.nwu.edu (Mitchell Maltenfort) writes:


>	I've FTP'd and unarchived the Stuttgart NN simulator successfully, but
>I keep having an error compiling the xgui interface: compiling funcdispl.c, it
>told me that "printf" cannot be redeclared.  Now the RS6000 has some odd ways
>of doing things, so I expect there's a simple, fixable bug.  Could someone
>please tell me what it is?  Thanks.

Mitchell,

This isn't the simple way, this is the cheap dirty way, but it seems to
work.  If Michael Vogt of Stuttgart reads this, please comment if you
think this shortcut causes problems.

Go to the xgui/sources directory.

type 'make list'

then

type 'make xgui'

I think that will produce the xgui file in the right place (for us, the
RS6000 directory).  Then I think I typed 'make install' to do some final
copying and you can then link the xgui file to 'snns' in the SNNSv2.1 
directory.

--
-------------------------------------------------------------------------------
Department of Physiology       : Tel: (071) 387 7050 x3248 : 
University College London      : Fax: (071) 383 7005       :  
Gower Street, London WC1E 6BT  : Email: s.kaul@ucl.ac.uk   :