From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: G.gorilla immunoglobulin alpha-1 constant region gene for
Date: 28 Jul 92 10:02:55 GMT
Distribution: bionet
Checksum: 03998     7

LOCUS       GORIGA1CR    2872 bp ds-DNA             PRI       28-JUL-1992
DEFINITION  G.gorilla immunoglobulin alpha-1 constant region gene for
            alpha-immunoglobulin heavy-chain constant region
ACCESSION   X53703
KEYWORDS    IgA heavy-chain constant region;
            immunoglobulin alpha-1 constant region gene.
SOURCE      Gorilla gorilla DNA.
  ORGANISM  Gorilla gorilla
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Pongidae.
REFERENCE   1  (bases 1 to 2872)
  AUTHORS   Kawamura,S., Tanabe,H., Watanabe,Y., Kurosaki,K., Saitou,N.,
            Omoto,K. and Ueda,S.
  JOURNAL   Mol. Biol. Evol. 8, 793-793 (1991)
  STANDARD  simple staff_entry
COMMENT     *source: tissue=lymph node; *source: clone_library=genomic;
            *source: clone=lambda L.G.Ig epsillon.25; *source: is_germline=Y;
            Related sequence; X15045 (bp 1-2037 are the same; bp 2038-2872
            represent a non-coding region additional to X15045)
            From EMBL    entry GGIGA1CR;  dated 28-NOV-1991.
FEATURES             Location/Qualifiers
     mRNA            join(290..594,807..1165,1394..1783)
                     /gene="Ig alpha-1"
     CDS             290..594
                     /note="Ig alpha-1 (102 AA) (290 is 2nd base incodon) (595
                     is 1st base in codon)"
                     /codon_start=2
                     /translation="IPDQPQGLPAEPLQHPARWGRGRRLPGPGLLPPGATQCDLERKR
                     TGCDCQKLPTQPGCLRGPVHHEQPADPAGHTVPRRQVRDMPRESLHESQPGCDCALP"
                     /partial
     exon            290..595
                     /number=1
     misc_feature    290..595
                     /note="constant region"
     intron          596..806
                     /number=1
     repeat_region   793..807
                     /note="direct repeat of hinge region"
     CDS             807..1165
                     /note="Ig alpha-1 (120 AA) (807 is 2nd base incodon) (1166
                     is 1st base in codon)"
                     /codon_start=3
                     /translation="PSTPPTPSPSTPPTPSPPCCHPRLSLHRPALEDLLLGSEANLTC
                     TLTGLRDASGVTFTWTPSSGKSAVEGPPERDLCGCYSVSSVLPGCAEPWNHGKTFTCT
                     AAYPESKTPLTATLSKS"
                     /partial
     exon            807..1166
                     /number=2
     misc_feature    807..1166
                     /note="constant region"
     repeat_region   808..822
                     /note="direct repeat of hinge region"
     repeat_region   823..837
                     /note="direct repeat of hinge region"
     repeat_region   832..846
                     /note="direct repeat of hinge region"
     repeat_region   847..861
                     /note="direct repeat of hinge region"
     intron          1167..1388
                     /number=2
     exon            1389..1780
                     /number=3
     misc_feature    1389..1780
                     /note="constant region"
     CDS             1394..1783
                     /note="Ig alpha-1 (131 AA) (1389 is 2nd base incodon)"
                     /codon_start=1
                     /translation="MFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGS
                     QELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQ
                     KTIDRLAGKPTHVNVSVVMAEVDGTCY"
     polyA_signal    1808..1813
                     /note="potential"
BASE COUNT      547 a    973 c    866 g    486 t
ORIGIN
        1 gagctcaggg gactcagcca ctccatggca gagccctgtt taatataact tgtgtctggg
       61 atggcctggg tcagaggccc tatctaggga gcatgttcag aaaccgtgtc gctgggatga
      121 gacacctggg tccaaccgca ggcccgtggt gcaggagctg tgtgaccttg gggctgtcac
      181 caggctgtct gtgctgggtt cctccagtat agaggagagg caggcacaga ctgccctcct
      241 ggggacatgg catgagggcc gcgtcctcac agcgcattct gtgttccagc atccccgacc
      301 agccccaagg tcttcccgct gagcctctgc agcacccagc cagatgggga cgtggtcgtc
      361 gcctgcctgg tccagggctt cttcccccag gagccactca gtgtgacctg gagcgaaagc
      421 ggacagggtg tgactgccag aaacttccca cccagccagg atgcctccgg ggacctgtac
      481 accacgagca gccagctgac cctgccggcc acacagtgcc cagacggcaa gtccgtgaca
      541 tgccacgtga atcactacac gaatcccagc caggatgtga ctgtgccctg ccgaggtcag
      601 agggcaggct ggggagtggg gcggggccac cccgtcctgc cctgacactg cgcctgcacc
      661 cgtgttcccc acagggagcc gccccgtcac tcacaccaga gtggaccatg ggccgagccc
      721 caggaggtgg tggacaggcc aggaggggcg aggcgggggc atggggaagg gtgttctgac
      781 cagctcaggc catctctcta ctccagttcc ctcaactcca cctaccccat ctccctcaac
      841 tccacctacc ccatctcccc catgctgcca cccccgactg tcgctgcacc gaccggccct
      901 cgaggacctg ctcttaggtt cagaagcgaa cctcacgtgc acactgaccg gcctgagaga
      961 tgcctcaggt gtcaccttca cctggacgcc ctcaagtggg aagagcgctg ttgaaggacc
     1021 acctgagcgt gacctctgtg gctgctacag cgtgtccagt gtcctgcctg gctgtgctga
     1081 gccatggaac catgggaaga ccttcacctg cactgctgcc taccccgagt ccaagacccc
     1141 actaaccgcc accctctcaa aatccggtgg gtccagaccc tgctcggggc cctgctcagt
     1201 gtcctggttt gcaaagcata ttcccagcct gcctcctccc tcccaatcct gggctccagt
     1261 gctcatgcca agtacagagg gaaactgagg caggctgagg ggccaggaca cagcccgggg
     1321 tgcccaccag agcagagggg ctctctcatc ccctgcccag ccccctgacc tggctctcta
     1381 ccctccagga aacatgttcc ggcccgaggt ccacctgcta ccgccgccgt cggaggagct
     1441 ggccctgaac gagctggtga cgctgacgtg cctggcacgt ggcttcagcc ccaaggacgt
     1501 gctggttcgc tggctgcagg ggtcacagga gctgccccgt gagaagtacc tgacttgggc
     1561 atcccggcag gagcccagcc agggcaccac caccttcgct gtgaccagca tactgcgcgt
     1621 ggcagccgag gactggaaga agggggacac cttctcctgc atggtgggcc atgaggccct
     1681 gccgctggcc ttcacacaga agaccatcga ccgcctggcg ggtaaaccca cccacgtcaa
     1741 tgtgtctgtt gtcatggcgg aggtggacgg cacctgctac tgagccgccc gcctgtcccc
     1801 acccctgaat aaactccatg ctcccccaag cagccccacg cttccatccg gcgcctgtct
     1861 gtccatcctc agggtctcag cacttgggaa agggccagag catggacagg gaagaatacc
     1921 ccctgccctg agcctcgggg ggcccctggc acccccatga gcctttccac cctggtgtga
     1981 gtgtgagttg tgagtgtgag agtgtgtggt gcaggaggcc tcgctggtgt gagatcttag
     2041 gtctgccgag gcaggcacag cccagggtgg gttctgagag acgcacatgc cccggagagt
     2101 tctgagtgag cagtggcacg gccgtttgtc cctgagagag ccgcctctgg ctgcagctgg
     2161 gagggaatag ggagggtaaa aggagcaggc tagccaagaa aggcgcaggt agtgggagga
     2221 gcggcgaggg agtgaggggc tggattccag ggccccactg ggaggacaag ctccaggagg
     2281 gccccaccac cctagtgggt gggcctcagg acgtcccact gacgcatgca ggaaggggca
     2341 cctcccacac tcacactcac gtatacgcct gagccctgca ggagcagaat gttcacagcc
     2401 cagacccagt tccagaaaag ccaggggagt cccctcccaa gaccccaagc tcagcctgct
     2461 cccccaggcc cctctggctt ccctgtgttt ccactgtgca cagctcaggg accaactcca
     2521 cagacccctc ccaggcagcc cctgctccct gcctggccaa gtctcccatc ccttcctaag
     2581 cccaactagg acccaaagca tagacaggga ggggccacgt ggggtggcat cagaagcagg
     2641 ccagtgagag agggcctgcc cagggccctc tgcatgcctc tggcttctgc ctggggctcc
     2701 caggagtgaa agaacagtcc cacaaccact gtggggacac ctggcaccca gactcccaca
     2761 agggggcagt ggggcccctg ctcgtgcctt agacatcttc cgggcctccc caggggcccc
     2821 cgccttctgg ctgcctccct ctgctctcag ggccaaggtg aggtggaggc ca
//