From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human peroxisome proliferator activated receptor mRNA, complete
Date: 29 Dec 92 01:28:11 GMT
Distribution: bionet
Checksum: 60896 7

LOCUS       HUMPPARA     3301 bp ss-mRNA            PRI       08-DEC-1992
DEFINITION  Human peroxisome proliferator activated receptor mRNA, complete
            cds.
ACCESSION   L07592
KEYWORDS    nuclear receptor; peroxisome proliferator activated receptor;
            steroid hormone receptor; steroid receptor superfamily;
            xenobiotic responsive element.
SOURCE      Homo sapiens (library: Lambda gt11) cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3301)
  AUTHORS   Schmidt,A., Endo,N., Rutledge,S., Vogel,R., Shinar,D. and
            Rodan,G.A.
  TITLE     Identification of a new member of the steroid hormone receptor
            superfamily that is activated by a peroxisome proliferator and
            fatty acids
  JOURNAL   Mol. Endocrinol. 6, 1634-1641 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             338..1663
                     /standard_name="NucI"
                     /note="member of steroid hormone receptor superfamily;
                     putative"
                     /product="peroxisome proliferator activated receptor"
                     /codon_start=1
                     /translation="MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTD
                     LSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTI
                     RMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGL
                     TANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIET
                     LWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLN
                     DQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEF
                     AVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDA
                     QYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY"
BASE COUNT      705 a   1014 c    879 g    696 t      7 others
ORIGIN      
        1 gaattctgcg gagcctgcgg gacggcggcg ggttggcccg taggcagccg ggacagtgtt
       61 gtacagtgtt ttgggcatgc acgtgatact cacacagtgg cttctgctca ccaacagatg
      121 aagacagatg caccaacgag ggtctggaat ggtctggagt ggtctggaaa gcagggtcag
      181 atacccctgg aaaactgaag cccgtggagc aatgatctct acaggactgc ttcaaggctg
      241 atgggaacca ccctgtagag gtccatctgc gttcagaccc agacgatgcc agagctatga
      301 ctgggcctgc aggtgtggcg ccgaggggag atcagccatg gagcagccac aggaggaagc
      361 ccctgaggtc cgggaagagg aggagaaaga ggaagtggca gaggcagaag gagccccaga
      421 gctcaatggg ggaccacagc atgcacttcc ttccagcagc tacacagacc tctcccggag
      481 ctcctcgcca ccctcactgc tggaccaact gcagatgggc tgtgacgggg cctcatgcgg
      541 cagcctcaac atggagtgcc gggtgtgcgg ggacaaggca tcgggcttcc actacggtgt
      601 tcatgcatgt gaggggtgca agggcttctt ccgtcgtacg atccgcatga agctggagta
      661 cgagaagtgt gagcgcagct gcaagattca gaagaagaac cgcaacaagt gccagtactg
      721 ccgcttccag aagtgcctgg cactgggcat gtcacacaac gctatccgtt ttggtcggat
      781 gccggaggct gagaagagga agctggtggc agggctgact gcaaacgagg ggagccagta
      841 caacccacag gtggccgacc tgaaggcctt ctccaagcac atctacaatg cctacctgaa
      901 aaacttcaac atgaccaaaa agaaggcccg cagcatcctc accggcaaag ccagccacac
      961 ggcgcccttt gtgatccacg acatcgagac attgtggcag gcagagaagg ggctggtgtg
     1021 gaagcagttg gtgaatggcc tgcctcccta caaggagatc agcgtgcacg tcttctaccg
     1081 ctgccagtgc accacagtgg agaccgtgcg ggagctcact gagttcgcca agagcatccc
     1141 cagcttcagc agcctcttcc tcaacgacca ggttaccctt ctcaagtatg gcgtgcacga
     1201 ggccatcttc gccatgctgg cctctatcgt caacaaggac gggctgctgg tagccaacgg
     1261 cagtggcttt gtcacccgtg agttcctgcg cagcctccgc aaacccttca gtgatatcat
     1321 tgagcctaag tttgaatttg ctgtcaagtt caacgccctg gaacttgatg acagtgacct
     1381 ggccctattc attgcggcca tcattctgtg tggagaccgg ccaggcctca tgaacgttcc
     1441 acgggtggag gctatccagg acaccatcct gcgtgccctc gaattccacc tgcaggccaa
     1501 ccaccctgat gcccagtacc tcttccccaa gctgctgcag aagatggctg acctgcggca
     1561 actggtcacc gagcacgccc agatgatgca gcggatcaag aagaccgaaa ccgagacctc
     1621 gctgcaccct ctgctccagg agatctacaa ggacatgtac taacggcggc acccaggcct
     1681 ccctgcagac tccaatgggg ccagcactgg aggggcccac ccacatgact tttccattga
     1741 ccagctctct tcctgtcttt gttgtctccc tctttctcag ttcctctttc ttttctaatt
     1801 cctgttgctc tgtttcttcc tttctgtagg tttctctctt cccttctccc ttctcccttg
     1861 ccctcccttt ctctctccta tccccacgtc tgtcctcctt tcttattctg tgagatgttt
     1921 tgtattattt caccagcagc atagaacagg acctctgctt ttgcacacct tttccccagg
     1981 agcagaagag agtgggcctg ccctctgccc catcattgca cctgcaggct taggtcctca
     2041 cttctgtctc ctgtcttcag agcaaaagac ttgagccatc caaagaaaca ctaagctctc
     2101 tgggcctggg ttccagggaa ggctaagcat ggcctggact gactgcagcc ccctatagtc
     2161 atggggtccc tgctgcaaag gacagtggca gaccccggca gtagagccga gatgcctccc
     2221 caagactgtc attgcccctc cgatcgtgag gccacccact gacccaatga tcctctccag
     2281 cagcacacct cagccccact gacacccagt gtccttccat cttcacactg gtttgccagg
     2341 ccaatgttgc tgatggcccc tccagcacac acacataagc actgaaatca ctttacctgc
     2401 aggcaccatg cacctccctt ccctccctga ggcaggtgag aacccagaga gaggggcctg
     2461 caggtgagca ggcagggctg ggccaggtct ccggggaggc aggggtcctg caggtcctgg
     2521 tgggtcagcc cagcacctcg cccagtggga gcttcccggg ataaactgag cctgttcatt
     2581 ctgatgtcca tttgtcccaa tagctctact gccctcccct tcccctttac tcagcccagc
     2641 tggccaccta gaagtctccc tgcacagcct ctagtgtccg gggaccttgt gggaccagtc
     2701 ccacaccgct ggtccctgcc ctcccctgct cccaggttga ggtgcgctca cctcagagca
     2761 gggccaaagc acagctgggc atgccatgtc tgagcggcgc agagccctcc aggcctgcag
     2821 gggcaagggg ctggctggag tctcagagca cagaggtagg agaactgggg ttcaagccca
     2881 ggcttcctgg gtcctgcctg gtcctccctc ccaaggagcc attctatgtg actctgggtg
     2941 gaagtgccca gcccctgcct gacggnnnnn nngatcactc tctgctggca ggattcttcc
     3001 cgctccccac ctacccagct gatgggggtt ggggtgcttc tttcagccaa ggctatgaag
     3061 ggacagctgc tgggacccac ctcccccctt ccccggccac atgccgcgtc cctgccccca
     3121 cccgggtctg gtgctgagga tacagctctt ctcagtgtct gaacaatctc caaaattgaa
     3181 atgtatattt ttgctaggag ccccagcttc ctgtgttttt aatataaata gtgtacacag
     3241 actgacgaaa ctttaaataa atgggaatta aatatttaaa aaaaaaagcg gccgcgaatt
     3301 c
//