From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mRNA for HLA-Cw12, complete cds.
Date: 3 Jan 93 22:06:35 GMT
Distribution: bionet
Checksum: 21705 5

LOCUS       HUMHLACW12   1427 bp ss-mRNA            PRI       21-DEC-1992
DEFINITION  Human mRNA for HLA-Cw12, complete cds.
ACCESSION   D12471
KEYWORDS    HLA-Cw12; HLA-class I; beta-2 microglobulin; transmembrane protein.
SOURCE      Homo sapiens (haplotype A24,B52,Cw12,DR2,DQ1,DPw9) lymphocyte B
            cell cell line AKIBA cDNA to mRNA, clone pC68.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Takata,H., Inoko,H., Ando,A., Haranaka,M., Watanabe,B., Tsuji,K.
            and Iri,H.
  TITLE     Cloning and analysis of HLA class I cDNA encoding a new HLA-C
            specificity Cx52
  JOURNAL   Immunogenetics 28, 265-270 (1988)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1427)
  AUTHORS   Takata,H., Sonoda,A., Beck,S., Heyes,J.M., Bodmer,J.G. and Inoko,H.
  TITLE     Full nucleotide sequence of an HLA allele Cw*1201 and production of
            monoclonal antibodies recognizing the serological 'blank'
            specificity, namely Cw12 by a transfectant system
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     Submitted (24-JUN-1992) on tape to DDBJ by: Hajime Takata Dept. of
            Molecular Life Science Tokai Univ. School of Medicine Bohseidai,
            Isehara Kanagawa 259-11 Japan Phone:  0463-93-1121 Fax:
            0463-92-4750

               [1]  sites.
FEATURES             Location/Qualifiers
     CDS             1..1101
                     /gene="Cw*1201"
                     /product="HLA-Cw12"
                     /codon_start=1
                     /translation="MRVMAPRTLILLLSGALALTETWAGSHSMRYFYTAVSRPGRGEP
                     RFIAVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSL
                     RNLRGYYNQSEAGSHTLQRMYGCDLGPDGRLLRGYDQVAYDGKDYIALNEDLRSWTAA
                     DTAAQITQRKWEAAREAEQWRAYLEGTCVEWLRRYLENGKETLQRAEHPKTHVTHHPV
                     SDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSG
                     EEQRYTCHVQHEGLPEPLTLRWEPSSQPTIPIVGIVAGLAVLAVLAVLGAVMAVVMCR
                     RKSSGGKGGSCSQAASSNSAQGSDESLIACKA"
BASE COUNT      283 a    430 c    444 g    270 t
ORIGIN      Map position 6p21.3.
        1 atgcgggtca tggcgccccg aaccctcatc ctgctgctct cgggagccct ggccctgacc
       61 gagacctggg ccggctccca ctccatgagg tatttctaca ccgccgtgtc ccggcccggc
      121 cgcggagagc cccgcttcat cgcagtgggc tacgtggacg acacgcagtt cgtgcggttc
      181 gacagcgacg ccgcgagtcc aagaggggag ccgcgggcgc cgtgggtgga gcaggagggg
      241 ccggagtatt gggaccggga gacacagaag tacaagcgcc aggcacaggc tgaccgagtg
      301 agcctgcgga acctgcgcgg ctactacaac cagagcgagg ccgggtctca caccctccag
      361 aggatgtacg gctgcgacct ggggcccgac gggcgcctcc tccgcgggta tgaccaggtc
      421 gcctacgacg gcaaggatta catcgccctg aacgaggacc tgcgctcctg gaccgctgcg
      481 gacacggcgg ctcagatcac ccagcgcaag tgggaggcgg cccgtgaggc ggagcagtgg
      541 agagcctacc tggagggcac gtgcgtggag tggctccgca gatacctgga gaacgggaag
      601 gagacgctgc agcgcgcgga acacccaaag acacacgtga cccaccatcc cgtctctgac
      661 catgaggcca ccctgaggtg ctgggccctg ggcttctacc ctgcggagat cacactgacc
      721 tggcagcggg atggcgagga ccaaactcag gacaccgagc ttgtggagac caggccagca
      781 ggagatggaa ccttccagaa gtgggcagct gtggtggtgc cttctggaga agagcagaga
      841 tacacgtgcc atgtgcagca cgaggggctg ccagagcccc tcaccctgag atgggagcca
      901 tcttcccagc ccaccatccc catcgtgggc atcgttgctg gcctggctgt cctggctgtc
      961 ctagctgtcc taggagctgt gatggctgtt gtgatgtgta ggaggaagag ctcaggtgga
     1021 aaaggaggga gctgctctca ggctgcgtcc agcaacagtg cccagggctc tgatgagtct
     1081 ctcatcgctt gtaaagcctg agacagctgc ctgtgtggga ctgagatgca ggatttcttc
     1141 acacctctcc tttgtgactt caagagcctc tggcatctct ttctgcaaag gcatctgaat
     1201 gtgtctgcgt tcctgttagc ataatgtgag gaggtggaga gacagcccac cccctgtcca
     1261 ccgtgacccc tgtccccaca ctgacctgtg ttccctcccc gatcatcttt cctgttccag
     1321 agaagtgggc tggatgtctc catctctgtc tcaactttac gtgtactgag ctgcaacttc
     1381 ttacttccct actgaaaata agaatctgaa tataaatttg ttttctc
//