From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mRNA for Pit-1/GHF-1, complete cds.
Date: 29 Jul 92 10:02:59 GMT
Distribution: bionet
Checksum: 52725     4

LOCUS       HUMPIT1GHF   1262 bp ss-mRNA            PRI       29-JUL-1992
DEFINITION  Human mRNA for Pit-1/GHF-1, complete cds.
ACCESSION   D10216 D01114
KEYWORDS    DNA binding protein; POU-domain; Pit-1/GHF-1; homeo box.
SOURCE      Homo sapiens pituitary cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1262)
  AUTHORS   Tatsumi,K.-., Notomi,T., Amino,N. and Miyai,K.
  TITLE     Nucleotide sequence of the complementary DNA for human Pit-1/GHF-1
  JOURNAL   Biochim. Biophys. Acta 1129, 231-234 (1992)
  STANDARD  full staff_review
COMMENT     Data kindly submitted in computer readable form by:
            Tatsumi Ke-ita
            Dapartment of Laboratory Medicine
            Osaka University Medical School
            Fukushima-ku
            Osaka 553
            Japan
            Phone:  06-451-0051
            Fax:    06-451-8742
FEATURES             Location/Qualifiers
     CDS             126..1001
                     /function="pituitary-specific POU-domain DNA binding
                     factor"
                     /product="Pit-1/GHF-1"
                     /gene="pit-1/GHF-1"
                     /codon_start=1
                     /translation="MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNV
                     MSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDP
                     TAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAV
                     HGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRR
                     TTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSL
                     NQSLFSISKEHLECR"
     polyA_signal    1229..1234
     polyA_signal    1243..1248
BASE COUNT      405 a    246 c    244 g    367 t
ORIGIN
        1 ctcagagcct tcctgatgta tatatgcagg tagtgagaat tgaatcggcc ctttgagaca
       61 gtaatataat aaaactctga tttggggagc agcggttctc cttatttttc tactctcttg
      121 tgggaatgag ttgccaagct tttacttcgg ctgatacctt tatacctctg aattctgacg
      181 cctctgcaac tctgcctctg ataatgcatc acagtgctgc cgagtgtcta ccagtctcca
      241 accatgccac caatgtgatg tctacagcaa caggacttca ttattctgtt ccttcctgtc
      301 attatggaaa ccagccatca acctatggag tgatggcagg tagtttaacc ccttgtcttt
      361 ataaatttcc tgaccacacc ttgagtcatg gatttcctcc tatacaccag cctcttctgg
      421 cagaggaccc cacagctgct gatttcaagc aggaactcag gcggaaaagt aaattggtgg
      481 aagagccaat agacatggat tctccagaaa tcagagaact tgaaaagttt gccaatgaat
      541 ttaaagtgag acgaattaaa ttaggataca cccagacaaa tgttggggag gccctggcag
      601 ctgtgcatgg ctctgaattc agtcaaacaa caatctgccg atttgaaaat ctgcagctca
      661 gctttaaaaa tgcatgcaaa ctgaaagcaa tattatccaa atggctggag gaagctgagc
      721 aagtaggagc tttgtacaat gaaaaagtgg gagcaaatga aaggaaaaga aaacgaagaa
      781 caactataag cattgctgct aaagatgctc tggagagaca ctttggagaa cagaataaac
      841 cttcttctca agagatcatg aggatggctg aagaactgaa tctggagaaa gaagtagtaa
      901 gagtttggtt ttgcaaccgg aggcagagag aaaaacgggt gaaaacaagt ctgaatcaga
      961 gtttattttc tatttctaag gaacatcttg agtgcagata agatttttct attgtataat
     1021 agcctttttc tcccgtttca ttcctttctc ttcctcaaca aaaacagaaa ttacttggtt
     1081 gacttaaaat cattttatat caatagcttt tacagaagct ttacttttcc actttttttt
     1141 aaaaaaaaga aaccaacaat ttaaattata ttgatgttat ttacttaaaa taattattct
     1201 cagaagccac attatctatt ttaagccaaa tatattaaca gtaataaaat gatctctctg
     1261 tc
//