From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human rhinovirus type 14 polyprotein gene.
Date: 6 Nov 92 18:28:40 GMT
Distribution: bionet
Checksum: 13695 13

LOCUS       HRV14POL     7212 bp ds-DNA             VRL       02-NOV-1992
DEFINITION  Human rhinovirus type 14 polyprotein gene.
ACCESSION   L05355
KEYWORDS    polyprotein.
SOURCE      Human rhinovirus 14 (strain 1059) DNA.
  ORGANISM  Human rhinovirus 14
            Viridae; ss-RNA nonenveloped viruses; Isometric ss-RNA viruses;
            Picornaviridae; Rhinovirus.
REFERENCE   1  (bases 1 to 7212)
  AUTHORS   Lee,W.-M., Mornoe,S. and Rueckert,R.R.
  TITLE     Role of maturation cleavage on infectivity of picornaviruses:
            Activation of an infectosome
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             629..7168
                     /product="polyprotein"
                     /codon_start=1
                     /translation="MGAQVSTQKSGSHENQNILTNGSNQTFTVINYYKDAASTSSAGQ
                     SLSMDPSKFTEPVKDLMLKGAPALNSPNVEACGYSDRVQQITLGNSTITTQEAANAVV
                     CYAEWPEYLPDVDASDVNKTSKPDTSVCRFYTLDSKTWTTGSKGWCWKLPDALKDMGV
                     FGQNMFFHSLGRSGYTVHVQCNATKFHSGCLLVVVIPEHQLASHEGGNVSVKYTFTHP
                     GERGIDLSSANEVGGPVKDVIYNMNGTLLGNLLIFPHQFINLRTNNTATIVIPYINSV
                     PIDSMTRHNNVSLMVIPIAPLTVPTGATPSLPITVTIAPMCTEFSGIRSKSIVPQGLP
                     TTTLPGSGQFLTTDDRQSPSALPNYEPTPRIHIPGKVHNLLEIIQVDTLIPMNNTHTK
                     DEVNSYLIPLNANRQNEQVFGTNLFIGDGVFKTTLLGEIVQYYTHWSGSLRFSLMYTG
                     PALSSAKLILAYTPPGARGPQDRREAMLGTHVVWDIGLQSTIVMTIPWTSGVQFRYTD
                     PDTYTSAGFLSCWYQTSLILPPETTGQVYLLSFISACPDFKLRLMKDTQTISQTVALT
                     EGLGDELEEVIVEKTKQTVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTTY
                     MHFNGSETDVECFLGRAACVHVTEIQNKDATGIDNHREAKLFNDWKINLSSLVQLRKK
                     LELFTYVRFDSEYTILATASQPDSANYSSNLVVQAMYVPPGAPNPKEWDDYTWQSASN
                     PSVFFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGITVLNHMGSMAFRIVNE
                     HDEHKTLVKIRVYHRAKHVEAWIPRAPRALPYTSIGRTNYPKNTEPVIKKRKGDIKSY
                     GLGPRYGGIYTSNVKIMNYHLMTPEDHHNLIAPYPNRDLAIVSTGGHGAETIPHCNCT
                     SGVYYSTYYRKYYPIICEKPTNIWIEGNPYYPSRFQAGVMKGVGPAEPGDCGGILRCI
                     HGPIGLLTAGGSGYVCFADIRQLECIAEEQGLSDYITGLGRAFGVGFTDQISTKVTEL
                     QEVAKDFLTTKVLSKVVKMVSALVIICRNHDDLVTVTATLALLGCDGSPWRFLKMYIS
                     KHFQVPYIERQANDGWFRKFNDACNAAKGLEWIANKISKLIEWIKNKVLPQAKEKLEF
                     CSKLKQLDILERQITTMHISNPTQEKREQLFNNVLWLEQMSQKFAPHYAVESKRIREL
                     KNKMVNYMQFKSKQRTEPVCVLIHGTPGSGKSLTTSIVGRAIAEHFNSAVYSLPPDPK
                     HFDGYQQQEVVIMDDLNQNPDGQDISMFCQMVSSVDFLPPMASLDNKGMLFTSNFVLA
                     STNSNTLSPPTILNPEALVRRFGFDLDICLHTTYTKNGKLNAGMSTKTCKDCHQPSNF
                     KKCCPLVCGKAISLVDRTTNVRYSVDQLVTAIISDFKSKMQITDSLETLFQGPVYKDL
                     EIDVCNTPPPECINDLLKSVDSEEIREYCKKKKWIIPEIPTNIERAMNQASMIINTIL
                     MFVSTLGIVYVIYKLFAQTQGPYSGNPPHNKLKAPTLRPVVVQGPNTEFALSLLRKNI
                     MTITTSKGEFTGLGIHDRVCVIPTHAQPGDDVLVNGQKIRVKDKYKLVDPENINLELT
                     VLTLDRNEKFRDIRGFISEDLEGVDATLVVHSNNFTNTILEVGPVTMAGLINLSSTPT
                     NRMIRYDYATKTGQCGGVLCATGKIFGIHVGGNGRQGFSAQLKKQYFVEKQGQVIARH
                     KVREFNINPVNTPTKSKLHPSVFYDVFPGDKEPAVLSDNDPRLEVKLTESLFSKYKGN
                     VNTEPTENMLVAVDHYAGQLLSLDIPTSELTLKEALYGVDGLEPIDITTSAGFPYVSL
                     GIKKRDILNKETQDTEKMKFYLDKYGIDLPLVTYIKDELRSVDKVRLGKSRLIEASSL
                     NDSVNMRMKLGNLYKAFHQNPGVLTGSAVGCDPDVFWSVIPCLMDGHLMAFDYSNFDA
                     SLSPVWFVCLEKVLTKLGFAGSSLIQSICNTHHIFRDEIYVVEGGMPSGCSGTSIFNS
                     MINNIIIRTLILDAYKGIDLDKLKILAYGDDLIVSYPYELDPQVLATLGKNYGLTITP
                     PDKSETFTKMTWENLTFLKRYFKPDQQFPFLVHPVMPMKDIHESIRWTKDPKNTQDHV
                     RSLCMLAWHSGEKEYNEFIQKIRTTDIGKCLILPEYSVLRRRWLDLF"
BASE COUNT     2313 a   1460 c   1475 g   1964 t
ORIGIN      
        1 ttaaaacagc ggatgggtat cccaccattc gacccattgg gtgtagtact ctggtactat
       61 gtacctttgt acgcctgttt ctccccaacc acccttcctt aaaattccca cccatgaaac
      121 gttagaagct tgacattaaa gtacaatagg tggcgccata tccaatggtg tctatgtaca
      181 agcacttctg tttccccgga gcgaggtata ggctgtaccc actgccaaaa gcctttaacc
      241 gttatccgcc aaccaactac gtaacagtta gtaccatctt gttcttgact ggacgttcga
      301 tcaggtggat tttccctcca ctagtttggt cgatgaggct aggaattccc cacgggtgac
      361 cgtgtcctag cctgcgtggc ggccaaccca gcttatgctg ggacgccctt ttaaggacat
      421 ggtgtgaaga ctcgcatgtg cttggttgtg agtcctccgg cccctgaatg cggctaacct
      481 taaccctgga gccttatgcc acgatccagt ggttgtaagg tcgtaatgag caactccggg
      541 acgggaccga ctactttggg tgtccgtgtt tctcattttt cttcatattg tcttatggtc
      601 acagcatata tatacatata ctgtgatcat gggcgctcag gtttctacac agaaaagtgg
      661 atctcacgaa aatcaaaaca ttttgaccaa tggatcaaat cagactttca cagttataaa
      721 ttactataag gatgcagcaa gtacatcatc agctggtcaa tcactgtcaa tggacccatc
      781 taagtttaca gaaccagtta aagatctcat gcttaagggt gcaccagcat tgaattcacc
      841 caatgttgag gcctgtggtt atagtgatag agtacaacaa atcacactcg ggaattcaac
      901 aataacaaca caagaagcag ccaacgctgt tgtgtgttat gctgaatggc cagagtacct
      961 tccagatgtg gacgctagtg atgtcaataa aacttcaaaa ccagacactt ctgtctgtag
     1021 gttttacaca ttggatagta agacatggac aacaggttct aaaggctggt gctggaaatt
     1081 accagatgca ctcaaagata tgggtgtgtt cgggcaaaac atgtttttcc actcactagg
     1141 aagatcaggt tacacagtac acgttcagtg caatgccaca aaattccata gcggttgtct
     1201 acttgtagtt gtaataccag aacaccaact ggcttcacat gagggtggca atgtttcagt
     1261 taaatacaca ttcacgcatc caggtgaacg tggtatagat ttatcatctg caaatgaagt
     1321 gggagggcct gtcaaggatg tcatatacaa tatgaatggt actttattag gaaatctgct
     1381 cattttccct caccagttca ttaatctaag aaccaataat acagccacaa tagtgatacc
     1441 atacataaac tcagtaccca ttgattcaat gacacgtcac aacaatgtct cactgatggt
     1501 catccctatt gcccctctta cagtaccaac tggagcaact ccctcactcc ctataacagt
     1561 cacaatagca cctatgtgca ctgagttctc tgggataagg tccaagtcaa ttgtgccaca
     1621 aggtttgcca actacaactt tgccggggtc aggacaattc ttgaccacag atgacaggca
     1681 atcccccagt gcactgccaa attatgagcc aactccaaga atacacatac cagggaaagt
     1741 tcataacttg ctagaaatta tacaggtaga tacactcatt cctatgaaca acacgcatac
     1801 aaaagatgag gttaacagtt acctcatacc actaaatgca aacaggcaaa atgagcaggt
     1861 ttttgggaca aacctgttta ttggtgatgg ggtcttcaaa actactcttc tgggtgaaat
     1921 tgttcagtac tatacacatt ggtctggatc acttagattc tctttgatgt atactggtcc
     1981 tgccttgtcc agtgctaaac tcattctagc atacaccccg cctggtgctc gtggtccaca
     2041 ggacaggaga gaagcaatgc taggtactca tgttgtctgg gatattggtc tgcaatccac
     2101 catagtaatg acaataccat ggacatcagg ggtgcagttt agatatactg atccagatac
     2161 atacaccagt gctggctttc tatcatgttg gtatcaaact tctcttatac ttcccccaga
     2221 aacgaccggc caggtctact tattatcatt cataagtgca tgtccagatt ttaagcttag
     2281 gctgatgaaa gatactcaaa ctatctcaca gactgttgca ctcactgaag gcttaggtga
     2341 tgaattagaa gaagtcatcg ttgagaaaac gaaacagacg gtggcctcaa tctcatctgg
     2401 tccaaaacac acacaaaaag tccccatact aactgcaaac gaaacagggg ccacaatgcc
     2461 tgttcttcca tcagacagca tagaaaccag aactacctac atgcacttta atggttcaga
     2521 aactgatgta gaatgctttt tgggtcgtgc agcttgtgtg catgtaactg aaatacaaaa
     2581 caaagatgct actggaatag ataatcacag agaagcaaaa ttgttcaatg attggaaaat
     2641 caacctgtcc agccttgtcc aacttagaaa gaaactagaa ctcttcactt atgttaggtt
     2701 tgattctgag tataccatac tggccactgc atctcaacct gattcagcaa actattcaag
     2761 caatttggtg gtccaagcca tgtatgttcc acctggtgcc ccgaatccaa aagagtggga
     2821 cgattacaca tggcaaagtg cttcaaaccc cagtgtattc ttcaaggtgg gggatacatc
     2881 caggtttagt gtgccttatg taggattggc atcagcatat aattgttttt atgatggtta
     2941 ctcacatgat gatgcagaaa ctcagtatgg cataactgtt ctaaaccata tgggtagtat
     3001 ggcattcaga atagtaaatg aacatgatga acataaaact cttgtcaaga tcagagttta
     3061 tcacagggca aagcacgttg aagcatggat tccaagagca cccagagcac taccctacac
     3121 atcaataggg cgcacaaatt atcctaagaa tacagaacca gtaattaaga agaggaaagg
     3181 tgacattaaa tcctatggtt taggacctag gtacggtggg atttatacat caaatgttaa
     3241 aataatgaat taccacttga tgacaccaga agaccaccat aatctgatag caccctatcc
     3301 aaatagagat ttagcaatag tctcaacagg aggacatggt gcagaaacaa taccacactg
     3361 taactgtaca tcaggtgttt actattccac atattacaga aagtattacc ccataatttg
     3421 tgaaaagccc accaacatct ggattgaagg aaacccttat tacccaagta ggtttcaagc
     3481 aggagtgatg aaaggggttg ggccagcaga accaggagac tgcggtggga ttttgagatg
     3541 catacatggt cccattggat tgttaacagc tggaggtagt ggatatgttt gttttgctga
     3601 catacgacag ttggagtgta tcgcagagga acaggggctg agtgattaca tcacaggttt
     3661 gggtagagct tttggtgtcg ggttcactga ccaaatctca acaaaagtca cagaactaca
     3721 agaagtggcg aaagatttcc tcaccacaaa agttttgtcc aaagtggtca aaatggtttc
     3781 agctttagtg atcatttgca gaaatcatga tgacttggtc actgttacgg ccactctagc
     3841 actacttgga tgtgatggat ctccctggag atttctgaag atgtacattt ccaaacactt
     3901 tcaggtgcct tacattgaaa gacaagcaaa tgatggatgg ttcagaaagt ttaatgatgc
     3961 atgtaatgct gcaaagggat tggaatggat tgctaataag atttccaaac tgattgaatg
     4021 gataaaaaac aaagtacttc cccaagccaa agaaaaacta gaattttgta gtaaactcaa
     4081 acaacttgat atactagaga gacaaataac caccatgcat atctcgaatc caacacagga
     4141 aaaacgagag cagttgttca acaacgtatt gtggttggaa caaatgtcgc aaaagtttgc
     4201 cccacattat gccgttgaat caaaaagaat cagggaactc aagaacaaaa tggtaaatta
     4261 tatgcaattt aaaagtaaac aaagaactga accagtgtgt gtattaatcc atggtacacc
     4321 cggttctggt aaatcattaa caacatccat tgtgggacgt gcaattgcag aacacttcaa
     4381 ttcagcagta tattcacttc caccagatcc caagcacttt gatggttatc agcaacagga
     4441 agttgtgatt atggatgatc tgaaccaaaa tccagatgga caggatataa gcatgttttg
     4501 tcaaatggtt tcttcagtgg atttcttgcc tccaatggct agtttagata acaagggcat
     4561 gttattcacc agtaattttg ttctagcctc cacaaattct aacacactaa gccccccaac
     4621 aatcttgaat cctgaagctt tagtcaggag atttggtttt gacctggata tatgtttgca
     4681 tactacctac acaaagaatg gaaaactcaa tgcaggcatg tcaaccaaga catgcaaaga
     4741 ttgccatcaa ccatctaatt tcaagaaatg ttgccccctg gtctgtggaa aagctattag
     4801 cttggtagac agaactacca acgttaggta tagtgtggat caactggtca cagctattat
     4861 aagtgatttc aagagcaaaa tgcaaattac agattcccta gaaacactgt ttcaaggacc
     4921 agtgtataaa gatttagaga ttgatgtttg caacacacca cctccagaat gtatcaacga
     4981 tttactgaaa tctgtagatt cagaagagat tagggaatat tgtaagaaga agaaatggat
     5041 tatacctgaa attcctacca acatagaaag ggctatgaat caagccagca tgattattaa
     5101 tactattctg atgtttgtca gtacattagg tattgtttat gtcatttata aattgtttgc
     5161 tcaaactcaa ggaccatatt ctggtaaccc gcctcacaat aaactaaaag ccccaacttt
     5221 acgcccagtt gttgtgcaag gaccaaacac agaatttgca ctatccctgt taaggaaaaa
     5281 cataatgact ataacaacct caaagggaga gttcacaggg ttaggcatac atgatcgtgt
     5341 ctgtgtgata cccacacacg cacagcctgg tgatgatgta ctagtgaatg gtcagaaaat
     5401 tagagttaag gataagtaca aattagtaga tccagagaac attaatctag agcttacagt
     5461 gttgacttta gatagaaatg aaaaattcag agatatcagg ggatttatat cagaagatct
     5521 agaaggtgtg gatgccactt tggtagtaca ttcaaataac tttaccaaca ctatcttaga
     5581 agttggccct gtaacaatgg caggacttat taatttgagt agcaccccca ctaacagaat
     5641 gattcgttat gattatgcaa caaaaactgg gcagtgtgga ggtgtgctgt gtgctactgg
     5701 taagatcttt ggtattcatg ttggcggtaa tggaagacaa ggattttcag ctcaacttaa
     5761 aaaacaatat tttgtagaga aacaaggcca agtaatagct agacataagg ttagggagtt
     5821 taacataaat ccagtcaaca cgccaaccaa gtcaaaatta catcccagtg tattctatga
     5881 tgttttccca ggtgacaagg aacctgctgt attgagtgac aatgatccca gactggaagt
     5941 taaattgact gaatcattat tctctaagta caaggggaat gtaaatacgg aacccactga
     6001 aaatatgctt gtggctgtag accattatgc agggcaacta ttatcactag atatccccac
     6061 ttctgaactt acactaaaag aagcattata tggagtagat ggactagaac ctatagatat
     6121 tacaaccagt gcaggatttc cctatgtgag tcttgggatc aaaaagagag acattctgaa
     6181 caaagagacc caggacacag aaaagatgaa gttttatcta gacaagtatg gcattgactt
     6241 gcctctagtt acatatatta aggatgaatt aagaagtgtt gacaaagtcc gattagggaa
     6301 aagtagatta attgaagcct ccagtttgaa tgattctgtt aacatgagaa tgaaactagg
     6361 caacctttac aaagcattcc atcaaaatcc cggtgttctg actgggtcag cagtgggttg
     6421 tgatcctgat gtgttttggt ctgtcatccc ttgcttaatg gatgggcacc tgatggcatt
     6481 tgattactct aattttgatg cctctttgtc accagtttgg tttgtctgtc tagagaaggt
     6541 tttgaccaag ttaggctttg caggctcttc attaattcaa tcaatttgta atacccatca
     6601 tatctttagg gatgaaatat atgtggttga aggtggcatg ccctcagggt gttcaggaac
     6661 cagcatattc aattccatga tcaacaacat aatcattagg actttgatat tagatgcata
     6721 taaaggaata gatttagaca aacttaaaat cttagcttac ggtgatgatt tgattgtttc
     6781 ttatccttat gaactggatc cacaagtgtt ggcaactctt ggtaaaaatt atggactaac
     6841 catcacaccc ccagacaaat ctgaaacttt tacaaaaatg acatgggaaa acttgacatt
     6901 tttaaagaga tacttcaagc ctgatcaaca atttcccttt ttggttcacc cagttatgcc
     6961 catgaaagat atacatgagt caatcagatg gacaaaggat cctaaaaaca cacaggatca
     7021 cgtccgatca ttatgcatgt tagcatggca ctcaggagaa aaagagtaca atgaattcat
     7081 tcagaagatc agaactactg acattggaaa atgtctaatt ctcccagaat acagcgtact
     7141 taggaggcgc tggttggacc tcttttaggt taacaatata gacacttaat ttgagtagaa
     7201 gtaggagttt at
//