From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: PSD-95=dlg tumor suppressor homolog [rats, postsynaptic density
Date: 27 Jan 93 05:57:52 GMT
Distribution: bionet
Checksum: 52609 7

LOCUS       S118782      3083 bp    mRNA            ROD       14-JAN-1993
DEFINITION  PSD-95=dlg tumor suppressor homolog [rats, postsynaptic density
            fraction, mRNA, 3083 nt]
ACCESSION   S49464 M96853
KEYWORDS    .
SOURCE      rats postsynaptic density fraction
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 3083)
  AUTHORS   Cho,K.O., Hunt,C.A. and Kennedy,M.B.
  TITLE     The rat brain postsynaptic density fraction contains a homolog of
            the Drosophila discs-large tumor suppressor protein.
  JOURNAL   Neuron 9, 929-942 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 118782] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 2.  The authors begin their numbering
            at -57.  Zero is not present in the numbering.
FEATURES             Location/Qualifiers
     CDS             58..2232
                     /note="dlg tumor suppressor homolog;  For the protein
                     sequence (NCBI gibbsq 118783):  Method: conceptual
                     translation with partial peptide sequencing.  This
                     sequence comes from Fig. 2."
                     /product="PSD-95"
                     /codon_start=1
                     /translation="MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDT
                     LEAPGYELQVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPG
                     GAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVME
                     IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV
                     GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSS
                     YLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE
                     GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQY
                     KPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQ
                     ALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWG
                     SSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHT
                     TRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGK
                     HCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQ
                     EFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPARERL"
BASE COUNT      709 a    865 c    857 g    652 t
ORIGIN      
        1 gcaaaactcc aatgaagtca gagcccccta ctcgccgccg cggccaggcc ccccaacatg
       61 gactgtctct gtatagtgac aaccaagaaa taccgctacc aagatgaaga cacgccccct
      121 ctggaacaca gcccggccca cctccccaac caggccaatt ctccccctgt gattgtcaac
      181 acggacaccc tagaagcccc aggatatgag ttgcaggtga atggaacaga gggggagatg
      241 gagtatgagg agatcacatt ggaaaggggt aactcaggtc tgggcttcag catcgcaggt
      301 ggcactgaca acccgcacat cggtgacgac ccgtccattt ttatcaccaa gatcattcct
      361 ggtggggctg cagcccagga tggccgcctc agggtcaatg acagcatcct gtttgtaaat
      421 gaagtggatg ttcgggaggt gacccattca gctgcggtgg aggccctcaa agaggcaggt
      481 tccatcgttc gcctctatgt catgcgccgg aaacccccag ccgaaaaggt catggagatc
      541 aaactcatca aagggcctaa aggacttggc ttcagcattg cggggggcgt tgggaaccag
      601 cacatccctg gagataacag catctatgta acgaagatca tcgaaggagg tgctgcccac
      661 aaggatggca ggttgcagat tggagacaag atcctggcgg tcaacagtgt ggggctggag
      721 gacgtcatgc acgaggatgc cgtggcagcc ctgaagaaca catatgacgt tgtgtaccta
      781 aaggtggcca agcccagcaa tgcctacctg agtgacagct atgctccccc agacatcaca
      841 acctcgtatt ctcagcacct ggacaatgag atcagtcata gcagctactt gggcactgac
      901 taccccacag ccatgacccc cacttcccct cggcgctact cccctgtggc caaggacctg
      961 ctgggggagg aagacattcc ccgggaacca aggcggatcg tgatccatcg gggctccacc
     1021 ggcctgggct tcaacatcgt gggcggcgag gatggtgaag gcatcttcat ctccttcatc
     1081 cttgctgggg gtccagccga cctcagtggg gagctacgga agggggacca gatcctgtcg
     1141 gtcaatggtg ttgacctccg caatgccagt cacgaacagg ctgccattgc cctgaagaat
     1201 gcgggtcaga cggtcacgat catcgctcag tataaaccag aagagtatag tcgattcgag
     1261 gccaagatcc atgatcttcg ggaacagctc atgaatagta gcctaggctc agggactgca
     1321 tccttgcgaa gcaaccccaa gaggggcttc tacattaggg ccctgtttga ttacgacaag
     1381 accaaggact gcggtttctt gagccaggcc ctgagcttcc gcttcgggga tgtgcttcat
     1441 gtcattgacg ctggtgacga agagtggtgg caagcacggc gggtccactc cgacagtgag
     1501 accgacgaca ttggcttcat tcccagcaaa cggcgggtcg agcgacgaga gtggtcaagg
     1561 ttaaaggcca aggactgggg ctccagctct ggatcacagg gtcgagaaga ctcggttctg
     1621 agctatgaga cggtgaccca gatggaagtg cactatgctc gtcccatcat catccttgga
     1681 cccaccaaag accgtgccaa cgatgatctt ctctccgagt tccccgacaa gtttggatcc
     1741 tgtgtccctc atacgacacg tcctaagcgg gaatatgaga tagacggccg ggattaccac
     1801 tttgtctcct cccgggagaa aatggagaag gacatccagg cacacaagtt cattgaggct
     1861 ggccagtaca acagccacct ctatgggacc agcgtccagt ctgtgcgaga ggtagcagag
     1921 caggggaagc actgcatcct cgatgtctcg gccaatgccg tgcggcggct gcaggcggcc
     1981 cacctgcacc ccatcgccat cttcatccgt ccccgctccc tggagaatgt gctagagatc
     2041 aataagcgga tcacagagga gcaagcccgg aaagccttcg acagagccac gaagctggag
     2101 caggagttca cagagtgctt ctcagccatc gtagagggcg acagctttga agagatctat
     2161 cacaaagtga aacgtgtcat tgaagacctc tcaggcccct acatctgggt cccagcccga
     2221 gagagactct gattcctgcc ctggcttggc ctggactcac cctgcctcca ccacatgggc
     2281 ccttggtgtg gactgaatag cccaagtcct ttgtacccca gcctcccttc ccacccttct
     2341 tatttatttc ctttctaact ggatcgagcc cactggaggg gggacactcc tctgcatgta
     2401 tccctgcaac ccagatcagg gcccctggac cccaagaacc tggggtctgg gggaggggag
     2461 ctgggctcct ggttccgagc ccttgctcct taggacccct acccccgccc gcccccatgc
     2521 acacatagac ccactggggg cctctgccct ccccattttc tcccacacac attccagaag
     2581 tcagggcccc tctcaaggag tacccgctgt agggatgcag ggccacaggc ttccgcgctc
     2641 tcctgaggca ggggctgggg tcacccctgc cccatcataa ctccccatgc catttgagtt
     2701 ctcatttatt ttctccattt ttttcttctc aaaggtggtt tttgggggga gacgcatggg
     2761 ggctctcctg agggtcccct gtctttcaca cacctcccac cttttttctt tgctggtttg
     2821 catgagtgga aggtctaact gtgggctttt ttttttcctg ggattttatt ttattttatt
     2881 tcattttatt tttttgggaa aaggggaggg atgggtctag ggagtgggga atatgggagg
     2941 ggggtggggg ggcaaggggt caggggttgg gtgtccggga gccaggggag gacaggaaat
     3001 gctgccgcct tctgcaattt atttattttt tcttttgaga gagtgaaagg aagagacaga
     3061 cacttgaaaa aaaaaaaaaa aaa
//