From: zhilkin@peter.ibd.nrc.ca (Peter Zhilkin)
Newsgroups: bionet.jobs
Subject: Comp. Biol./Protein analysis/Looking for a job
Date: 21 Dec 92 20:26:28 GMT
Distribution: bionet
Original-To: biojobs@uk.ac.daresbury, zhilkin@ca.nrc.ibd.zeno

Dear Respective Employer,

   I am looking for an opportunity to do basic or applied research
in the fields of theoretical analysis of structure-function
relationships in proteins, protein engineering or related areas.

   I'm MSc in chemical physics. I dealt and participated in develop-
ment of application of various theoretical methods for analysis of
amino acid sequences (7 years of experience).

   I took part in next research projects :

- Theoretical analysis of structure-function
  relationships and thermostability for complement C5a.

- The search for functionally important regions of
  proteins and peptide on the base of amino acid
  sequences.

- Some principles of protein engineering of vaccines.

- Theoretical construction of helix-bundle vaccine
  against HIV and hepatitis B viruses.

- Determination of the unknown recognition sequences
  of restriction endonucleases on the base of lengths
  cleavage fragments.


   I have extensive experience (9 years) in programming as well.
I dealt with IBM Mainframe (4 years), IBM PC (DOS, 6 years),
Silicon Graphics (UNIX, 1.5 years), programming languages -
C (6 years), Fortran (5 years), Assembler 8086 (4 years)
and IBM-370 (2 years).

   I am currently working in the Informatics group of the Institute
for Biodiagnostics, National Research Council of Canada. My duties
include programming and development of algorithms and methods to
analyze multidimensional data, support of PC computers, including
networking, and consulting of PC users.

 Thank you for your consideration.

		Yours sincerely, Peter Zhilkin

------------------------------------------------------------------------

                        Curriculum Vitae

Name:			Peter Zhilkin

Date of birth:		April 18, 1962

Citizenship: 		Russia

Marital status:		Married, 2 children

Present address:	435 Ellice Ave. Winnipeg Manitoba R3B 1Y6
			tel:   (204)-984-4540
			fax:   (204)-984-5472
			email: zhilkin@zeno.ibd.nrc.ca

Education:		Novosibirsk State University		1979-1984
			Physics department, MSc in
			Chemical Physics

			Advanced Physics-Mathematics
			school at Novosibirsk University	1978-1979

Employment history:	Research Officer, Institute for Bio-
			diagnostics, NRC Canada			1992-present

			Research Officer, Institute for Bio-
			logical Sciences, NRC, Canada		1991-1992

			Research Officer			1987-1991
			All-Union Institute of Molecular
			Biology (IMB), Koltsovo, Novosibirsk
			region, Russia

			Engineer, IMB				1985-1987

			Research fellow, IMB			1984-1985

Experience:		Application of mathematical methods and programming
			for sequence analysis. Theoretical analysis of
			structure-function relationships in proteins.

Research projects:	Theoretical analysis of structure-function
			relationships and thermostability for complement C5a.

			The search for functionally important regions of
			proteins and peptide on the base of amino acid
			sequences.

			Some principles of protein engineering of vaccines.

			Theoretical construction of helix-bundle vaccine
			against HIV and hepatitis B viruses.

			Determination of the unknown recognition sequences
			of restriction endonucleases on the base of lengths
			of cleavage fragments.

			The modelling of the internal dynamics of cyclo-
			sporin A on the base of NMR relaxation data.

Current project:	Application of mathematical methods and programming
			for multidimensional data analysis.

Computer experience:	9 years of programming experience
			7 years of programming applied to molecular biology.
			Hardware:  IBM Mainframe    (4 years)
				   IBM PC           (6 years)
				   Silicon Graphics (1.5 year)
			Operating systems:
				   MVT              (IBM Mainframe)
				   MSDOS            (IBM PC)
				   UNIX             (Silicon Graphics)
			Languages: C                (6 years)
				   Fortran          (5 years)
				   Assembler for IBM Mainframe (2 years)
				   Assembler for IBM PC   (4 years).

Invited Symposia:	International Symposium "Modelling and Computer Methods
			in Molecular Biology & Genetics", Novosibirsk, Russia,
			1990

			International Congress "Peptides", Leningrad, Russia,
			1988, report "Prediction of functionally important
			regions of proteins and peptides on the base of amino
			acid sequence".

			Symposiums on Theoretical Investigations and Data Bases
			in Molecular Biology & Genetics, Novosibirsk, Russia,
			1988, 1986.

			Symposiums on Theoretical Investigations and Data Bases
			in Molecular Biology & Genetics, Moscow, Russia,
			1985, 1987.


				Some publications

1. A. M. Eroshkin, V. I. Fomin, P. A. Zhilkin, V. A. Kulichkov
   "Protein fragment variability analysis and some principles of protein
   engineerig of vaccines"
   Protein Engineering, 1990, vol.3, no.5, pp.425-431

2. S. Kh. Degtyarev, N. I. Rechkunova, A. A. Kolyhalov, V. S. Dedkov,
   P. A. Zhilkin
   "II-Q restriction endonucleases - new class of type II enzymes"
   Nucleic Acids Research, 1990, vol.18, no.19, pp.5807-5810

3. Eroshkin A. M., Zhilkin P. A., Nikulin A. E.
   "Identification of function and functionally important regions of
   polypeptides coded by vaccinia virus"
   Abstr. of All-Union Conference "Theor. investigations and data bases in
   molec. biol. and genetics", ed. N.A. Kolchanov, 1988, Novosibirsk, 44-45.
   (in Russian)

4. Fomin V. I., Eroshkin A. M., Zhilkin P. A., Nikulin A. E..
   "Variable fragments data base and its use in design of chimeric proteins"
   In "Modelling and computer methods in molecular biology and genetics".-
   ed. N.A. Kolchanov - Abstr. of Intern. Conf., Novosibirsk, 1990, p.235 

5. Eroshkin A. M., Zhilkin P. A.
   "Using of profile of resemblance to host serum proteins for detection
   of immunodominant regions of protein and peptides"
   In "Mathematical modelling of immune system and infections process".-
   All-Union Conference, Koltsovo, Novosibirsk region, 1989, p.19-20
   (in Russian)

6. Eroshkin A. M., Zhilkin P. A., Popkov I. K., Kulichkov V. A.
   "Structural and physico-chemical properties of amino acids of
   functionally important regions of proteins"
   Biophysics (USSR), 1987, vol.32, p.972-980 (in Russian)

7. Eroshkin A. M., Zhilkin P. A., Shamin V.V.
   "Fully artificial proteins with predetermined tertiary structure -
   a novel approach to vaccine design. Anti-HIV vaccine development"
   Abstract, VII International Conference on AIDS, Florence, 
   16-21 June 1991, Abstract M.A.1319. 

8. Zhilkin P. A. and  Eroshkin A. M.
   "Protein and peptide functionally  important regions search method from
   amino acid sequence"
   Biopolymers and Cells (USSR), 1990, 6,36-42 (in Russian)

9. Eroshkin A. M., Zhilkin P.A., Shamin V.V.
   "Artificial protein-vaccines with predetermined tertiary structure - a 
   novel object for protein engineering. Application to anti HIV-1 vaccine
   design"
   Submitted to Protein Engineering. 

10.Fomin V. I., Eroshkin A. M., Zhilkin P. A., Nikulin A. E.  
   "Protein variable fragments data base and its use in chimeric 
   protein design planning"
   Submitted to CABIOS. 

11.Eroshkin A. M., Zhilkin P. A., Fomin V. I.
   "Algorithm and computer  program  Pro_Anal  for  analysis  of relationship 
   between structure and activity in  a  family of proteins or 
   peptides"
   Submitted to CABIOS.   

---
Peter Zhilkin
IBD NRC					Tel:   +1-204-984-4540
435 Ellice Ave. Winnipeg		Fax:   +1-204-984-5472
Manitoba R3B 1Y6 Canada			Email: zhilkin@zeno.ibd.nrc.ca