From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Aplysia californica (clone pApNPY10 and pApNPY32) neuropeptide Y
Date: 29 Dec 92 19:56:37 GMT
Distribution: bionet
Checksum: 32443 5

LOCUS       APLPPNPY     1497 bp ss-mRNA            INV       10-DEC-1992
DEFINITION  Aplysia californica (clone pApNPY10 and pApNPY32) neuropeptide Y
            mRNA, complete cds.
ACCESSION   M98854
KEYWORDS    neuropeptide Y.
SOURCE      Aplysia californica (library: P.J. Pfaffinger and E.R. Kandel's
            Bluescript library) central nervous system cDNA to mRNA.
  ORGANISM  Aplysia californica
            Eukaryota; Animalia; Eumetazoa; Mollusca; Gastropoda;
            Opisthobranchia; Anaspidea; Aplysiidae.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Rajpara,S.M., Garcia,P.D., Roberts,R., Eliassen,J.C., Owens,D.F.,
            Maltby,D., Myers,R.M. and Mayeri,E.
  TITLE     Identification and molecular cloning of a neuropeptide Y homolog
            that produces rolonged inhibition in Aplysia neurons
  JOURNAL   Neuron 9, 505-513 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     repeat_unit     1..151
                     /rpt_type=direct
     repeat_region   152..187
                     /rpt_family="CT repeat"
                     /rpt_unit=152..153
     sig_peptide     507..569
                     /codon_start=1
     mat_peptide     570..689
                     /function="produces prolonged inhibition of identified
                     neurons L3 and L6"
                     /product="neuropeptide Y"
                     /codon_start=1
     mat_peptide     690..782
                     /standard_name="C-terminal peptide"
                     /codon_start=1
                     /note="putative"
     misc_signal     690..692
                     /note="C-terminal amidation signal"
     misc_signal     693..698
                     /note="Lys-Arg cleavage site"
     misc_signal     711..719
                     /note="Arg-Lys-Arg potential cleavage site"
     repeat_region   929..988
                     /rpt_family="ATA repeat"
                     /rpt_unit=929..931
     repeat_unit     1104..1256
                     /rpt_type=direct
     repeat_region   1256..1325
                     /rpt_family="CT repeat"
                     /rpt_unit=1256..1257
     CDS             507..785
                     /product="neuropeptide Y"
                     /codon_start=1
                     /translation="MQRVILVVLLLSCMAVLSVRADNSEMLAPPPRPEEFTSAQQLRQ
                     YLAALNEYYSIMGRPRFGKRGDSFRKREFFRTNGERYPEDAAAWTEFQ"
BASE COUNT      433 a    388 c    269 g    407 t
ORIGIN      
        1 aggctgtaag cgacgcgact tgatagaatc gagccgtaag agtgctgtaa aagtgaaact
       61 agcttcaatg tcctgaagaa attgagcttt gaaatgacag gcagaatctc ccgttctctg
      121 ttccctgtat attctttgac ccatctgttt tctctctctc tctctctctc tccctctctc
      181 tctctctcac acacacacaa acgtgtggac acgggctggt ggtcttggtg aaatctcgag
      241 aaaacaacag agcaacagga aatagaacaa caagaagaag aaaaacaaag aagaagaagt
      301 aaaaagaaga agaaaaagaa gaagaaaaaa gaagaacagc ggacgaacat cgaccacaaa
      361 acaacaagca acattttcaa gagtctgcga gcgatagaaa attacttcaa gtcaacggaa
      421 aaagccttta ttcgagatta tcagctctct gtcaagttgt tacgaatttc taccgaaagt
      481 aacaaatcta gatcccaagg cccactatgc agagagtgat cctggtagtg ttgttgctgt
      541 cctgcatggc cgttctcagc gtgcgtgctg acaacagcga gatgttggcc ccgcccccac
      601 gacccgagga gttcacttcc gcccaacagt tgagacagta cctggcagcc ctcaacgagt
      661 actactccat catgggccga cccaggtttg gcaaaagagg tgactctttc agaaaaaggg
      721 aattcttcag aactaatggc gagagatacc ccgaagacgc cgcggcgtgg actgagttcc
      781 agtgagatcg tccccccacc gctgacgtca tcgagtggtc aagctttgat gtgaccgcca
      841 gcgaccatcc tcctgtccaa ctgttccacc actgttgact taaacttctt accatatcgt
      901 ttgggatcaa cttgtcaaaa gtttactgat aataataata ataataataa taataataat
      961 aataataata ataataataa taataataca acaaatagta tgttcaaaag tataaatgat
     1021 gataataaca gctttagtga aaaaaggcat atcaaaaata tagttcccgt ttatcttact
     1081 cttgggtagg attttgagag agaaggctgt aagcgacgcg acttgataga atcgagccgt
     1141 aagagtgctg taaaagtgaa actagcttca atgtcctgaa gaaattgagc tttgaaatga
     1201 caggcagaat ctcccgttct ctgttccctg tatattcttt gtacccatct gttttctctc
     1261 tctctctctc tctctctctc tctctctctc tctctctctc tctctctctc tctctctctc
     1321 tctctacttt tccttattcc tatctttgga tttagttctg tttcttttca ccttgttctc
     1381 tctatccctc gctccccctc cccacacgca cacacaccca accaaccacc ctctctcaca
     1441 cgctctttct ctcaactccc tctgtctcac tatctctctc ccctcactct ctctccc
//