HDTenEightyP/NetNews huggingface dataset:
From: jah@mits.mdata.fi (Jani A. Heinonen)
Subject: Re: Heroin
Organization: Microdata International Telecomm Service, Helsinki, Finland
Date: Wed, 9 Sep 1992 21:10:56 GMT

haba@lesti.hut.fi (Harri "Haba" Suomalainen) writes:

>I'guess it is more like the substance found the brains naturally
>(endorphines). It it very common drugs are modified slightly to get
>different efects. All mechanisms (like with morphine) are not completely
>understood even though reseptors are already found.

   No, it's not any closer to the endorphins than morphine. Endorphins are
proteins (endogenous opioid peptides), morphine is an alkaloid and heroin is
a semisynthetic derivative of it. It has acetyl groups (acetic acid radicals)
on both of the hydroxyls. Perhaps the carbonyls enable it to cross the blood-
brain barrier more readily? Just a wild guess. Anyone ever tried to synthesize
diformylmorphine?
-- 
Jani Heinonen                    "Tonight when I chase the dragon,
jah@mits.mdata.fi                 The water may turn to cherry wine
                                  And the silver will turn to gold
                                  Time out of mind."
Newsgroups: alt.drugs,alt.society.civil-liberty,talk.politics.drugs
From: n9020351@henson.cc.wwu.edu (James Douglas Del-Vecchio)
Subject: Re: JDs (was Re: Clinton in _Rolling Stone_ ...)
Organization: Western Washington University
Date: Fri, 11 Sep 1992 00:24:03 GMT

billn@hpcvaac.cv.hp.com (bill nelson) writes:



>: Trust an Angelino - they do have automatic weapons.  So does
>: everybody else around here; show up on New Years, when everybody
>: gives their arsenal some celebratory exercise...

>OK - maybe I should have been clearer. Please define an automatic weapon.

	An automatic weapon is a firearm which fires continiously so long 
as the trigger remains depressed.  i.e. only one pull of the trigger is
needed to empty a 20 rd clip, for example, rather than 20 seperate 
trigger pulls.

	Rather than the "PopPopPopPopPop" sound of a normal gun being fired 
fast, i.e. distinct shots, one would hear a continous racket for an instant,
(I have no typeable sound effect for this.  8^)

Jim Del Vecchio
From: u8951608@csdvax.csd.unsw.edu.au
Newsgroups: alt.drugs
Subject: Re: Sanity for A.C.T. Drug Laws
Date: 11 Sep 92 06:50:10 GMT
Organization: University of New South Wales

In article <machman.716098704@milton>, machman@milton.u.washington.edu (The Machman) writes:
> rjones@peg.pegasus.oz.au writes:
> 
>>"The ACT Government has taken the eminently sensible and
>>rational step of decriminalising marijuana and is to be
>>congratulated for that," said Democrat Richard Jones, MLC.
> 
> this is very encouraging.  but please tell us ig-nernt 'Muricans:
> what do the initials ACT stand for?

The Australian Capital Territory, a small self-governed area
enclosed by New South Wales, which has one major 'city', Canberra,
which hosts the Federal government. A bit like Washington D.C ?
The government referred to above is the local self-government, not
the Federal government, thus the decriminalisation does not
apply to most of the country (yet:-).

Jeremy
jeremy@rsc3.anu.edu.au
From: ck@iconix.oz.au (Chris Karadaglis)
Newsgroups: alt.drugs
Subject: Re: Pot Talk
Date: 11 Sep 92 03:47:47 GMT
Organization: Iconix Pty Ltd (World Headquarters)

In <j1moody-090992004723@lafmacconsultant.lafortune.lab.nd.edu> j1moody@darwin.cc.nd.edu (Humpty Dumpty) writes:


>What exactly do the phycho-active substances found in ganga do?
>Why do some who smoke have "psychedelic" experiences while others
>simply get sleepy and hungry (off the same joint)?

I was discussing this with my SO last night. I trip almost every time
I have a toke, whereas she just veges out. I think tripping with
mull is something that has to be learned.

Try this whilst having a toke: Hold your breath for at least 1/2 min
(this may take some practise!). Let it out and just relax for a bit.
Close your eyes and visualise a square. See if you can turn it into
a triangle. Play with this shape for a while. Rotate it, translate it,
etc. Open and shut your eyes quickly. You'll be left with a "burnt"
image of the room in your head. Try manipulating this image as you did
with the shape. This will take a bit of practise. Recall images from
memory and play with these. After a while, your thoughts will connect with
the images, and then your thoughts will free-form. Then just sit back and
enjoy the ride (or have another toke...).

Does anyone out there play around like this, or do most people veg out?

Shckwish!
Organization: Carnegie Mellon, Pittsburgh, PA
From: locklin@titan.ucc.umass.edu ()
Subject: Re: Legality of mushroom cultivation
Organization: Campus Crusade for Cthulhu
Date: Mon, 14 Sep 1992 19:52:57 GMT
X-Posted-From: titan.ucc.umass.edu
NNTP-Posting-Host: sol.ctr.columbia.edu


>that it will be a full two months before I have any shrooms in my
>possession (if ever).  I've never heard of any laws regarding the 
>growing/possession of these mushrooms however.  I have to assume that
>growing them is legal, since I bought the spores and kit for them at
>a legitimate store here in town, but does anyone know about US law
>in regard to the possession/consumption of them?  Not that I'm really
>worried, but I don't wanna go around boasting about what a great batch
>of shrooms I have if they're technically illegal.

You better believe they're illigal! (psilocybin mushrooms anyway)

Although, I believe only a couple species are illegal (P.Mexicanus), possession
of psilocin or psilocybin is quite illegal (& they are the active ingreedients)

Newsgroups: alt.drugs,talk.politics.drugs
From: locklin@titan.ucc.umass.edu ()
Subject: Desmanthus question
Organization: Campus Crusade for Cthulhu
Date: Fri, 4 Sep 1992 23:04:25 GMT
X-Posted-From: titan.ucc.umass.edu
X-Posted-Through: sol.ctr.columbia.edu


I've just gotten an "of the jungle..." catalogue. It states that desmanthus
has some indole alkaloids (other than DMT & company) in trace quantities
that inhibits the growth of seedlings. The suggestion was use of the extraction
as a natural herbicide. Anyone (Steve?) have a reference for this?
Do all indole alkaloids have this effect?
The label "herbicide" has rather negative connotations. 
Thanx in adv.

-Scott
From: u8951608@csdvax.csd.unsw.edu.au
Newsgroups: alt.drugs
Subject: Re: Onset Timing of Hallucinogens
Date: 2 Sep 92 16:00:47 GMT
Organization: University of New South Wales

In article <nfjn7=d.bprofane@netcom.com>, bprofane@netcom.com (Gert Niewahr) writes:
> 
> I've been wondering what the relationship of chemical structure and
> method of ingestion is to the onset rate of the various
> hallucinogens.  For instance, DMT has this killer reptutation in
> part because of the rapid onset of effects experienced by most
> users.  Yet isn't this more due to the fact that it is normally
> smoked or snorted than ingested orally, and that when it is
> ingested orally in ayahuasca the onset seems to be delayed and
> gradual as with LSD or psilocybin.  If either of these could be
> ingested in such a way as to rapidly insinuate itself in the
> bloodstream, would you get the same instant slam of hallucinations
> as with DMT?  Or is this rapid onset one of the inherent attributes
> of DMT?

Indeed, if LSD or psiloc(yb)in were taken parenterally, the onset would
be more rapid, and could be more overwhelming. Differences occur         
depending on the rate of diffusion of the substance from the
blood into the brain, and this would be the limiting factor,
determining the lag time. The delay for DMT is extremely small
(a few seconds).

In my opinion, the effect of DMT is qualitatively very different
from LSD and psiloc(yb)in, both in terms of physical and
mental effects, and this probably also contributes to its
reputation. Thus, injected psilocin might hit within a very few
minutes, but the effect would still be quite different from DMT.
Likewise, ayahuasca would probably be a quite different kind
of experience from oral psiloc(yb)in, despite having similar
kinetics. 

  Is there any reason LSD
> wouldn't be active if administered intravenously?

None, and the effective doses are comparable.

  Could you,
> theoretically, ingest LSD nasally as the substituent of an aerosol?

Yes. I have heard rumours of people snorting chopped blotter
to good effect.

> 
> I'd ask the same question of psilocybin except that I know it has
> to be converted into psilocin to be psychoactive and this normally
> occurs in your gut when you ingest it orally.  Yet if you had
> isolated psilocin, theoretically, would you get a rapid onset of
> effects if you administered it intravenously?

See above. I don't have the data on hand for the onset time of
injected psilocybin, but I suspect it is probably slightly longer
than that of DMT. The duration is, of course, much longer.
I would guess that psilocybin and psilocin would be equivalent
when injected, as when taken orally.

Jeremy
jeremy@rsc3.anu.edu.au
Newsgroups: alt.drugs
From: rlb@plex-1.ann-arbor.mi.us (Robin Billings)
Subject: Re: MAOI & shrooms
Organization: Plex-1, Michigan's Public Access Usenet Gateway  (Ann Arbor).
Date: Thu, 10 Sep 1992 23:03:13 GMT

There is a very powerful synergistic effect when dimethyltryptamine is
combined with MAO inhibitors in the traditional South American visionary
brew, ayahuasca, which contains harmine, tetrahydroharmine, and harmaline.
These same alkaloids are in the seeds and roots of Peganum harmala, which
has been used in conjunction with the roots of Desmanthus illinoensis (which
contain DMT) to produce a sort of North American ayahuasca.  Psilocybin is
4-phosphoryloxy-DMT and is also potentiated by an MAO inhibitor.  Chocolate
is typically consumed with psilocybin mushrooms as they not only cut the taste,
but also render a 2 gram dosage quite powerful through a mild MAO inhibition.

If one combines harmine/harmaline alkaloids, which are quite potent MAO
inhibitors, with psilocybin, the experience is greatly potentiated and
may result in a temporary psychosis that can last up to two weeks.  I have
observed this firsthand in a client who ingested 15 grams of Stropharia
cubensis (dry weight), which is a very substantial dose, and two grams of
powdered Peganum harmala seed.  In Terence McKenna's book, True Hallucinations,
he describes a similar incident in his brother, Dennis, after eating one
fresh Stropharia cubensis mushroom and drinking an ayahuasca mixture.
Unless one is prepared for such a journey, and has very patient and
supportive friends who will watch over one for a few weeks, I would strongly
recommend avoiding experimentation with this combination.
 
One can safely potentiate 1 to 2 grams of the mushroom with a tiny pinch
(and I mean quite literally a TINY pinch) of Peganum harmala seed to
produce a very intense, kundalini type psychedelic experience.  But even
at this dosage level, unless one has practiced some type of meditation 
technique to cultivate a calm, clear centeredness, it is quite easy to
find oneself being pulled off center by one's psychotic tendencies.
 
The problem with making authoritative statements regarding the interaction
of tryptamine psychedelics is that there is only anecdotal or case study
data to base one's theories upon.  No active research has ever been done
using more sophisticated methodology, such as radioactive tagging or
PET scans, to gather data on the nature of the metabolic processes these
compounds trigger in the brain/body.  This is one area that may reveal
a great deal about temporary psychoses on a biochemical level.  Anyone
out there interested in conducting such a study with lab animals?

Xref: sparky alt.drugs:15803 talk.politics.drugs:6310
From: brrian04@uctvax.uct.ac.za
Newsgroups: alt.drugs,talk.politics.drugs
Subject: Re: 900thousand babies born addicts in US
Date: 15 Sep 92 10:42:15 +0200
Organization: University of Cape Town

In article <1992Sep11.183843.780@csc.canterbury.ac.nz>, civl097@csc.canterbury.ac.nz writes:
> I'm sure I heard this on the TVNZ "News" tonight.
> 
> A US Senate report just released claims that 900000 babies have been
> born addicts, in the last three years!
> 
> Does anybody know anything about this. Have I heard these figures wrong?
> What are they addicted to?
> 
> Brandon Hutchison,University of Canterbury,Christchurch
>                   New Zealand
Probably Mother's milk.  Without proper documented evidence these reports can
be assumed to be nonsense.  What happened to the 375 000 'crack' babies per
year?

Swan Wulfgur			I turned silences and nights into words.
				What was unutterable, I wrote down.
brrian04@uctvax.uct.ac.za	I made the whirling world stand still.
ibarrett@casper.cs.uct.ac.za		- Arthur Rimbaud
						A Season in Hell

				Swans fly silently to the burning sky.

	Alcohol is a Drug	Caffeine is a Drug 	Nicotine is a Drug

				Are you Anti-Drugs?
From: shirriff@sprite.berkeley.edu (Ken Shirriff)
Newsgroups: alt.drugs
Subject: Re: Heroin
Date: 7 Sep 1992 20:32:48 GMT
Organization: University of California, Berkeley
NNTP-Posting-Host: hijack.berkeley.edu

In article <BAGCHI.92Sep6224054@quip.eecs.umich.edu> bagchi@eecs.umich.edu (Ranjan Drzzzzt!  Bagchi) writes:
>	The New York Times had an article this summer (either July
>or August) on the front page about a high-powered Manhattan
>executive who's been on and off heroin for the last 20 years.

The article is:
 "Executive's secret struggle with heroin's powerful grip. (many heroin users
	are not debilitated by using the drug)"
 New York Times v141 (Wed, July 22, 1992):A1(N), A1(L), col 1, 37 col in.

Ken Shirriff			shirriff@sprite.Berkeley.EDU
Newsgroups: alt.drugs
From: ctorres@cco.caltech.edu (Chon David Torres)
Subject: Re: THE HIDDEN STORY OF THE L.A. REBELLION
Organization: California Institute of Technology, Pasadena
Date: Sat, 12 Sep 1992 11:32:58 GMT

what the hell does this have to with DRUGS? Keep this crap off this 
group. I'd rather read about strychneine than see another post like that
one.
-chon
-- 
*******************************************************************************
ctorres@cco.caltech.edu                  	     ctorres@juliet.caltech.edu 
*******************************************************************************
Newsgroups: alt.drugs
From: hagerp@moose.cs.indiana.edu (Paul Hager)
Newsgroups: alt.drugs
Subject: Re: Idea for new drug - uses no chemicals.
Keywords: electric magnetic non-chemical
Date: 8 Sep 92 04:16:01 GMT
Organization: Computer Science, Indiana University

I didn't comment on the original post which suggesting using high
intensity magnetic fields to induce altered states of consciousness
because I expected someone else more knowledgeable in biomagnetics
to comment.  However, in the absense of of such comment I would
point out that high intensity, high frequency magnetic fields have
been suggested to be carcinogenic.  Also, I've never heard of such
fields being able to affect a persons brain in any way perceptible
to the person subjected to the field.  If such a thing were possible,
there'd be a lot of magnetic "heads" in the major nuclear and 
high-energy physics labs where such electromagnets abound.


-- 
paul hager		hagerp@moose.cs.indiana.edu

"I would give the Devil benefit of the law for my own safety's sake."
                       --from _A_Man_for_All_Seasons_ by Robert Bolt
Newsgroups: alt.drugs
From: j1moody@darwin.cc.nd.edu (Humpty Dumpty)
Subject: Re: Pot Talk
Followup-To: alt.drugs
Organization: The Wall
Date: Mon, 14 Sep 1992 06:09:45 GMT

The new High Times briefly addresses this issue, stating it has something
to do with the sensitivity of the receptors in the brain.

I've noticed there is a certain distinction between the people I know who
react hyper-sensitively and the people who "vegetablize" under the herb's 
influence.

Has anyone else noticed this?
Newsgroups: alt.drugs,talk.politics.drugs
From: feustel@netcom.com (David Feustel)
Subject: Re: "War Against Drugs a Failure"
Date: Sat, 12 Sep 92 00:30:18 GMT
Organization: DAFCO: OS/2 Software Support & Consulting
Keywords: interesting facts

The best way for the US to win the War on Drugs is to unconditionally
surrender and sue for peace.
-- 
Dave Feustel N9MYI <feustel@netcom.com>
 
RE Drug Warriors who enjoy making a "good" bust: I'm sure the Salem
Witch Hunters enjoyed their law enforcement achievements too.
From: "tom betz" <tom.betz@execnet.com>
Newsgroups: alt.drugs
Subject: holland drug classificati
Date: 7 Sep 92 02:22:17 EST
Reply-To: "tom betz" <tom.betz@execnet.com>
Distribution: alt
Organization: Executive Networks Information

Quoth I G Barrett regarding HOLLAND DRUG CLASSIFICATI on 09-06-92:

IG>The natural forms are NOT necessarily less potent.  Even if that was t
IG>true you could just take more!  Besides the damage caused by smoking 
IG>it, is itreally more harmful than a similar quantity of cocaine 
IG>consumed in cocaine?

Absolutely.  When taken as tea, or in the form of chewed coca leaves, 
consumption is self-limiting... it is practically impossible for one to 
consume a lethal dose, because the concentration of cocaine in the carrier 
is so small.

IG>There is very little factual information available on cocaine and 
IG>crack.

It is the same all over the world.  Once the Big Lie takes hold, it is a 
Herculean task to dislodge it.


---
  WinQwk 2.0 a#299  Half-idealism, Charlie, is the peritonitis of the soul.
--
Executive Network Information System  (914) 667-4567
International ILink Host
Newsgroups: alt.drugs,alt.psychoactives
From: eesnyder@boulder.Colorado.EDU (Eric E. Snyder)
Subject: Re: TIHKAL?
Organization: University of Colorado, Boulder
Date:  8 Sep 92 19:37:16 GMT

aankrom@nyx.cs.du.edu (Anthony Ankrom) writes:

>In article <1992Sep7.200102.6807@mits.mdata.fi> jah@mits.mdata.fi (Jani A
> Heinonen) writes:
>>   Has the book come out yet? If it has, where could it be ordered from?
>>If not, does anyone have any idea when it might?

> It's not out yet. It should be soon. How soon is soon I don't know...

Have I missed something here?  Does Shulgin have a new one on the rails?
_Tryptamines I Have Known And Loved_, perhaps?


---------------------------------------------------------------------------
TTGATTGCTAAACACTGGGCGGCGAATCAGGGTTGGGATCTGAACAAAGACGGTCAGATTCAGTTCGTACTGCTG
Eric E. Snyder                            
Department of MCD Biology              ...making feet for childrens' shoes.
University of Colorado, Boulder   
Boulder, Colorado 80309-0347
LeuIleAlaLysHisTrpAlaAlaAsnGlnGlyTrpAspLeuAsnLysAspGlyGlnIleGlnPheValLeuLeu
---------------------------------------------------------------------------


Newsgroups: alt.drugs
From: lamontg@carson.u.washington.edu (Lamont Granquist)
Subject: Re: [anonymous] I hope this finally works...
Organization: 'Operation: Mindcrime'
Date: Tue, 15 Sep 1992 21:21:33 GMT

billn@hpcvaac.cv.hp.com (bill nelson) writes:

>somesite@somewhere (Mr. Anonymous) writes:
>: 
>: 
>: Provided this test message works, alt.drugs now has an automatic anonymous
>: posting facility...
>
>Depends on what you mean by working. It shows as having been posted by
>you, Lamont.
>
>We will see what the header looks like, when someone else does a posting.

Actually, its not quite working.  There should be a signature, and 
somesite@somewhere should be replaced by the anonymous reply address.

Newsgroups: alt.drugs,alt.society.civil-liberty,talk.politics.drugs,talk.politics.guns,talk.politics.misc
From: llama@pooh.cc.utexas.edu (sine nomine)
Newsgroups: alt.drugs,talk.politics.drugs
Subject: Re: 900thousand babies born addicts in US
Date: 15 Sep 92 01:57:18 GMT
Followup-To: alt.drugs
X-Newsreader: Tin 1.1 PL5

civl097@csc.canterbury.ac.nz wrote:
: I'm sure I heard this on the TVNZ "News" tonight.
: 
: A US Senate report just released claims that 900000 babies have been
: born addicts, in the last three years!

this number sounds suspiciously high. does anyone know how many babies
total were born in the us in the last three years?  hmmmm... a reason
to drop by the library on the way home...

--
sine nomine
debbie martinson
"glass jaw, alcohol whore, cardboard cutout lying on the floor. lame-
brain's drunk again, stupid dumdum plumb cold insane... it makes me
feel so bad, so nice" -- pwei, "wake up, time to die"
Newsgroups: alt.drugs
From: aankrom@nyx.cs.du.edu (Anthony Ankrom)
Subject: Re: New designer drug
X-Disclaimer: Nyx is a public access Unix system run by the University
	of Denver for the Denver community.  The University has neither
	control over nor responsibility for the opinions of users.
Organization: Nyx, Public Access Unix at U. of Denver Math/CS dept.
Distribution: usa
Date: Fri, 11 Sep 92 16:56:25 GMT

In article <65643@cup.portal.com> tetra@cup.portal.com (daniel TetraHedon
willits) writes:
>Alan Harder writes:
>   > ...ingredients include acetone, toluene, muriatic or hydrochloric a
                     ^^^^^^^  (Key word here...)
id
>   > officials said."
>
>   > Coming soon to a dealer near your!
>
>Coming soon to a dealer near your favorite mortuary it sounds like!  I c
n't
>imagine what one could really concoct out of those ingredients except pe
haps
>some rather nasty, vaporous solvent.


 Chances are this is just what they FOUND in the lab. And of course they
don't want to give away the _secret_ ingredient! :-) Cathinone and
methcathinone are made from propiophenone which is brominated then reacted
with methylamine (or ammonia). This are the first steps in synthesizing
ephedrine except you just don't follow up with the final oxidation of the
ketone. SO what you have is an ehpedrine analaog that has an oxo instead
of a hydroxyl on the beta carbon (a ketone instead of an alcohol). How
potent this substance is I don't know. 
 Try doing a CARL search on cathinone. I did and got several references,
but the ones that interested me I couldn't get because none of the
libraries on campus subscribed to them. (If any of you wouldn't mind
sending me articles that I will reimburse you for, I would appreciate it.
Just e-mail me and we can discuss it then...)

St. Anthony


--
        CH3  O            CH(CH3)2        |      dadaMatrix
           >-P-S-CH2CH2-N<            VX  |                       
    CH3CH2O               CH(CH3)2        |     aankrom@nyx.cs.du.edu
                                          | A kinder gentler lobotomy...
From: 34AEJ7D@CMUVM.CSV.CMICH.EDU
Newsgroups: alt.drugs
Subject: DEA seeks "shoot-down" authority
Date: 4 Sep 92 21:10:08 GMT
Reply-To: bj496%Cleveland.Freenet.Edu@CMUVM.CSV.CMICH.EDU

I just saw this goodies on rec.aviation:

The  DEA  is seeking  authority  from  Congress  to  shoot down  any  aircraft
"suspected  of  being involved  in  drug  traffiking".  So far,  they  haven't
received it, but they have the borrowed F-16's ready... just in case.

Wonder if that includes passenger airliners? Probably - it wouldn't be the
first time for that one.

W. K. Gorman
Xref: sparky alt.drugs:15602 alt.society.civil-liberty:5732 talk.politics.drugs:6233
From: frazier@kona.cs.ucla.edu (Gregory Frazier)
Newsgroups: alt.drugs,alt.society.civil-liberty,talk.politics.drugs
Subject: Re: JDs (was Re: Clinton in _Rolling Stone_ ...)
Date: 10 Sep 92 22:16:14 GMT
Organization: UCLA, Computer Science Department
X-Newsreader: Tin 1.1 PL5

bill nelson (billn@hpcvaac.cv.hp.com) wrote:
: frazier@kona.cs.ucla.edu (Gregory Frazier) writes:
: : Trust an Angelino - they do have automatic weapons.  So does
: : everybody else around here; show up on New Years, when everybody
: : gives their arsenal some celebratory exercise...
: 
: OK - maybe I should have been clearer. Please define an automatic weapon.

One that goes rat-a-tat-tat much quicker than I think they
can move their trigger fingers.

--
"They thought to use and shame me but I win out by nature, because a true
freak cannot be made.  A true freak must be born." - Geek Love

Greg Frazier	frazier@CS.UCLA.EDU	!{ucbvax,rutgers}!ucla-cs!frazier
Newsgroups: alt.drugs