From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: C.elegans ced-4 gene
Date: 3 Jan 93 22:12:19 GMT
Distribution: bionet
Checksum: 61929 9

LOCUS       CELCED4A     4407 bp ds-DNA             INV       23-DEC-1992
DEFINITION  C.elegans ced-4 gene
ACCESSION   X69016
KEYWORDS    ced-4 gene; cell death.
SOURCE      Caenorhabditis elegans DNA.
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Animalia; Eumetazoa; Nematoda; Secernentea; Rhabditida;
            Rhabditina; Rhabditoidea; Rhabditidae.
REFERENCE   1  (bases 1 to 4407)
  AUTHORS   Yuan,J. and Horvitz,H.R.
  TITLE     The Caenorhabditis elegans cell death gene ced-4 encodes a novel
            protein and is expressed during the period of extensive programmed
            cell death
  JOURNAL   Development 116, 309-320 (1992)
  STANDARD  full automatic
COMMENT     From EMBL    entry CECED4A;  dated 14-DEC-1992.
FEATURES             Location/Qualifiers
     mRNA            join(968..1464,1516..1609,1654..1743,1930..1996,
                     2047..2384,2942..3217,3266..3371,3418..>3645)
                     /gene="ced-4"
                     /partial
     exon            968..1464
                     /number=1
                     /gene="ced-4"
     intron          1465..1515
                     /number=1
                     /gene="ced-4"
     exon            1516..1609
                     /number=2
                     /gene="ced-4"
     intron          1610..1653
                     /number=2
                     /gene="ced-4"
     exon            1654..1743
                     /number=3
                     /gene="ced-4"
     intron          1744..1929
                     /number=3
                     /gene="ced-4"
     exon            1930..1996
                     /number=4
                     /gene="ced-4"
     intron          1997..2046
                     /number=4
                     /gene="ced-4"
     exon            2047..2384
                     /number=5
                     /gene="ced-4"
     intron          2385..2941
                     /number=5
                     /gene="ced-4"
     exon            2942..3217
                     /number=6
                     /gene="ced-4"
     intron          3218..3265
                     /number=6
                     /gene="ced-4"
     exon            3266..3371
                     /number=7
                     /gene="ced-4"
     intron          3372..3417
                     /number=7
                     /gene="ced-4"
     exon            3418..>3645
                     /number=8
                     /gene="ced-4"
     CDS             join(1014..1464,1516..1609,1654..1743,1930..1996,
                     2047..2384,2942..3217,3266..3371,3418..3645)
                     /gene="ced-4"
                     /codon_start=1
                     /translation="MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELI
                     SKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLR
                     PVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGR
                     AGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLKSEDDLL
                     NFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVE
                     ISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLM
                     MFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSA
                     LAFAVVMPPGVDIPVKLWSCVIPVDICSNEEEQLDDEVADRLKRLSKRGALLSGKRMP
                     VLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNVSVPERHIPSHFQKFRR
                     SSASEMYPKTTEETVIRPEDFPKFMQLHQKFYDSLKNFACC"
BASE COUNT     1344 a    793 c    744 g   1524 t      2 others
ORIGIN      
        1 gaattcgcgt cgaatcattg tctgttcggt atcgattcag aaaccgaaac ttgtgatcga
       61 taacaagtca ttcaaacacg gcgaagatgt ctatgcgtat aacagaatat ttggagaaat
      121 gctcgcaaaa ctcgaaattg tcaccgataa aatgattaac ttgaaggggc taatgtaagt
      181 tatctgatgt ttctacaatt aaaaaaattg tttttttttc caaattaatt ttcgaagatt
      241 aacgaaaaac gattaaaaat caataaaacg caataaagag ggcttggctt tctttttaat
      301 ttaaattata atttttctga ttgttgtatg aagctacaaa atgtactgtt tttgtatttg
      361 aatattgtat tacagggttg ggattctcgg caaatatcag cgacagtgga agatttagaa
      421 gaaggacgtg tgacaatcac taagtcaaag agggaaagga taaaggattg tgatatttca
      481 ctgttttact cattcgcttt ttaaataaga actatatgcc gatttgccga tatatttttg
      541 tttattaggc ctctcacatt cctgtacaat gtttctacca aataaactgc atttttatct
      601 gaaaattcga atttattttt gtctactttt tactcgttgc attcgagatc agcatatctt
      661 ccggtctatt tatattcaac gatttttata aattagtact ccttcatgtt taatttcatt
      721 ttatctgtaa gctttactgt atttttttaa aatctttctt gcttctatct gattatacaa
      781 tgttctttac tcattttcaa ggtattttta tgcctcacaa tttatgcaca tttcgggctt
      841 ggagatttat cctctatatt acatgcctgt ttttttaaag gatataatgt ttaacaaata
      901 attttttatc aatgctattg tatattctcc agctaaccgt tgtttcgaaa acatcaccta
      961 gcattttaaa attcacaaaa tcttgcttcc ttataatcaa gaagattttt cagatgctct
     1021 gcgaaatcga atgccgcgct ttgagcacgg cacacacgag gctcatccac gactttgaac
     1081 cacgtgacgc attgacttat ttagaaggca aaaacatttt cacagaagat cattctgaac
     1141 ttatcagtaa aatgtcaact cgcctcgaga ggatcgccaa ttttcttcga atctatcgac
     1201 gtcaagcttc tgaacttgga ccactcatcg actttttcaa ctacaacaat caaagtcacc
     1261 ttgctgattt cctcgaagac tacatcgatt ttgcgataaa tgagccagat ctacttcgtc
     1321 cagtagtgat tgctccacaa ttttcccgac aaatgctcga taggaaacta ttgcttggga
     1381 atgttccaaa acaaatgaca tgctatattc gagagtatca cgtggatcga gtgatcaaaa
     1441 agctcgacga gatgtgtgat ttaggtgaga aaactggaag ctctcgtgtt tattataatc
     1501 ttgcttaaac ttcagactcc ttttttctgt ttctacacgg ccgagctgga tccggaaaat
     1561 cagtaattgc atcacaagct ctttcgaaat ctgaccaact tattggaatg tgagtggtat
     1621 tatctgaatc tacggatctt cattctatta cagaaattat gattcaatcg tttggctcaa
     1681 agatagtgga acagctccaa aatctacatt cgatttattt acggatattt tgctgatgct
     1741 aaagtgagtg aatagagtgc atgtaacatt cagcatgatt ttgaaattat gaaaatttga
     1801 cctggttagc ttttaatttg atatttcgtg acgcttgcat gttttgtgtg tttgaagacg
     1861 agcccgtgtt gtgagcgaca cggatgactc gcattcgatc accgacttca ttaaccgtgt
     1921 tctttcaaga agcgaagacg atcttctcaa tttcccatcg gtggagcatg tcacgtcagt
     1981 tgtactcaaa aggatggtaa gttgcttgcc gattctggta caatatctta aattattggt
     2041 ttttagatct gcaacgcact cattgatcgt ccaaatactt tattcgtatt tgatgacgta
     2101 gttcaagaag aaacaattcg ttgggctcag gagctacgtc ttcgatgtct tgtaactact
     2161 cgtgacgtgg aaatatcaaa tgctgcttct caaacatgcg aattcattga agtgacatca
     2221 ttggaaatcg atgaatgtta tgattttcta gaagcttatg gaatgccgat gcctgttgga
     2281 gaaaaagaag aagatgtgct taataaaaca atcgaactaa gcagtggaaa tccagcaacg
     2341 cttatgatgt ttttcaagtc ttgtgaaccg aaaacatttg aaaagtgagt gggacatacc
     2401 aatttgagac ttttaaaata atttattcta caataaaagt taatcaaaaa gtttcatagc
     2461 tgattgtctt taaattttac gaattgagga tcaaaatcaa gaattaggat cctggcacga
     2521 gagaaaactg tgtagctacc gtacccgaga gattttcttg atatttgcca tcgatttaat
     2581 tttttaagaa aattatcgtt ttacataatt gaacaagaga tacacggtct cgacccgacg
     2641 gaaatttttt aaatgaaagc gagtatgagc ctgttttcat tatttttcga ttttctcttg
     2701 ttgtttcttt ttatttaaag ccttttattt tgaaacaagt ctaaaaatat taaaaactga
     2761 ataaaatatt taaaaaaaat caagtaaaat agaaaaacag caaggctgga gactactgta
     2821 cttcttaaat ccgcatactc tttttattta atcattttcc ggaatgtcga aacgaaataa
     2881 tacattttta gtccaaaatc gctaggtata ttcttaaaat tatcaaacat tttgcattca
     2941 gaatggcaca gcttaataac aaattggaaa gtcgaggatt agtcggtgtt gaatgtatca
     3001 ccccttactc gtacaagtca ctcgcaatgg ctcttcaaag atgtgttgaa gttttgtcag
     3061 atgaggatcg aagtgctctt gctttcgcag ttgtgatgcc tcctggagtt gatatacccg
     3121 tcaagctatg gtcatgtgtt attccagttg atatttgttc aaatgaagaa gaacaattgg
     3181 atgatgaagt tgcggatcgg ttgaaaagac tcagcaagta tgagtcttga aatttgaaga
     3241 tttaaattaa cacttaaaat ttcagacgtg gagctcttct cagtggaaaa cgaatgcccg
     3301 ttttgacatt caaaattgat catattatcc atatgttctt gaaacacgtc gttgatgcac
     3361 aaactatcgc cgtatgctga aaatgtctca actttcaatt aaattttaaa ttttcagaat
     3421 ggaatctcaa ttctcgagca gcgtcttctt gaaataggaa acaataatgt atcagtaccg
     3481 gagcgacata taccatcaca tttccaaaaa ttccgtcgtt catcagccag tgagatgtat
     3541 ccaaaaacta cagaagaaac tgtgatccgt cctgaagact tcccaaagtt catgcaattg
     3601 caccagaaat tctatgactc cctcaaaaat tttgcatgct gttaaaacct atcgtgtaca
     3661 atattgcctg tatattcccc tcgaaatacg tttatacttt ttcgcacgag ttttctcatt
     3721 ttttcatttg tacttgtttt atttctctcc aaaatttcag atctatccca aatgttctta
     3781 aatttaatgt tttctacaga tactcaacac atcttgtttc atctcatcct tgcttttttt
     3841 tttcaaatat attcagtttc ttttataatt ttaattaatc gaattaatac attcacgtaa
     3901 agaatttcgt ggactattat tttatcgcat ccaaatgatt tattccctat tgttcgaaac
     3961 ttccaaattg atcattttta aacacgcctc attaaattga aagtcgtact tttagtctcg
     4021 aacatgaagt aagttatttt ctgtgttcta aattcaaagt gcattccaaa aggacatttg
     4081 atgagttttc acgaaaaccg taatttttac aatttccttt cagttttgaa gatgttcgat
     4141 ttctttcctc tgttggcgtc attactacat ttgctttgct gcttcacttt atcgagattc
     4201 ttgccatcaa tggagttcca tctagaccga tagcagtctt catatcatta tccctgtata
     4261 ttgtactgtt tcagtatttt aacttatcga ttacgtacta tattcagtgg ttcactgttt
     4321 tcggtcaatg ggtgacacgt gctcgacgan naattttcaa cgaacgcaat ctcctagtca
     4381 cttatcaacc aagagccctc acccatg
//