From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human high affinity IgE receptor beta chain gene, complete cds.
Date: 28 Jul 92 10:07:18 GMT
Distribution: bionet
Checksum: 02814    18

LOCUS       HUMRIGBCHA  11298 bp ds-DNA             PRI       28-JUL-1992
DEFINITION  Human high affinity IgE receptor beta chain gene, complete cds.
ACCESSION   M89796
KEYWORDS    IgE receptor beta chain.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 11298)
  AUTHORS   Kuester,H., Zhang,L., Brini,A.T., MacGlashan,D.W. and Kinet,J.-P.
  TITLE     The gene and cDNA for the human high affinity IgE receptor beta
            chain and expression of the complete human FcepsilonRI receptor
  JOURNAL   J. Biol. Chem. 267, 12782-12787 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             join(456..511,1381..1510,2026..2160,4475..4531,5079..5237,
                     5640..5738,7224..7322)
                     /product="high affinity IgE receptor beta chain"
                     /codon_start=1
                     /translation="MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASS
                     PPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPF
                     WGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIH
                     IHSCQKFFETKCFMASFSTEIVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRV
                     YEELNIYSATYSELEDPGEMSPPIDL"
     mRNA            join(354..511,1381..1510,2026..2160,4475..4531,5079..5237,
                     5640..5738,7224..10214)
                     /product="high affinity IgE receptor beta chain"
     exon            354..511
                     /number=1
                     /gene="high affinity IgE receptor beta chain"
     intron          512..1380
                     /number=1
                     /gene="high affinity IgE receptor beta chain"
     exon            1381..1510
                     /number=2
                     /gene="high affinity IgE receptor beta chain"
     intron          1511..2025
                     /number=2
                     /gene="high affinity IgE receptor beta chain"
     exon            2026..2160
                     /number=3
                     /gene="high affinity IgE receptor beta chain"
     intron          2161..4474
                     /number=3
                     /gene="high affinity IgE receptor beta chain"
     exon            4475..4531
                     /number=4
                     /gene="high affinity IgE receptor beta chain"
     intron          4532..5078
                     /number=4
                     /gene="high affinity IgE receptor beta chain"
     exon            5079..5237
                     /number=5
                     /gene="high affinity IgE receptor beta chain"
     intron          5238..5639
                     /number=5
                     /gene="high affinity IgE receptor beta chain"
     exon            5640..5738
                     /number=6
                     /gene="high affinity IgE receptor beta chain"
     intron          5739..7223
                     /number=6
                     /gene="high affinity IgE receptor beta chain"
     exon            7224..10214
                     /number=7
                     /gene="high affinity IgE receptor beta chain"
BASE COUNT     3470 a   2113 c   2283 g   3415 t     17 others
ORIGIN
        1 aagcttttca aaggtgcaat tggataactt ctgccatgag aaatggctga attgggacac
       61 aagtggggac aattccagaa gaagggcaca tctctttctt ttctgcagtt ctttctcacc
      121 ttctcaactc ctactaaaat gtctcatttt caggttctgt aaatcctgct agtctcaggc
      181 aaaattatgc tccaggagtc tcaaattttc ttatttcata ttagtcttta tttagtagac
      241 ttctcaattt ttctattcat cacaagtaaa agcctgttga tcttaatcag ccaagaaact
      301 tatctgtctg gcaaatgact tatgtataaa gagaatcatc aatgtcatga ggtaacccat
      361 ttcaactgcc tattcagagc atgcagtaag aggaaatcca ccaagtctca atataataat
      421 attctttatt cctggacagc tcggttaatg aaaaaatgga cacagaaagt aataggagag
      481 caaatcttgc tctcccacag gagccttcca ggtaggtaca aggtattatt tttttctacc
      541 ctcagtcact tgtggcaggg gaagtcatag tcacggtgct taggagatga aactttattg
      601 atttaggcat ggatccatct agtttaatta atatattggg tatgaggaag ctacttgctg
      661 tactttccat gtggttctct ctccctggag aggaacattt ttactcagct tgcaaactgg
      721 aaatagattt tctcacatta gaagctcatt ttctgggtat gagacaggag agttcatact
      781 gtgtatgtag atctctggct tctgggtctg acatgtgctg agggacacat atccttcaca
      841 catgctttta taaatacttg ataaagtaac ctgcttcttg attggtcttt ataatccata
      901 agctgtggga tgcttctctg aagatgaaaa tagtaataga gtcccatcta gctattcaaa
      961 gccattcctt cattgtattc tgtgcacatg aagttggggt ttgttactga caaaatatat
     1021 tcagatacat ttctatgtta aaaggattgt gagatgcata ggtaaatgtg tttattttca
     1081 gttttacttg tcaacataga tgaatgagaa agaacttgaa agtaacactg gattaagaat
     1141 aggaaaattt ggcatggatt ttgctccatt ttgtcccatc taatcacttg gatagtgttc
     1201 aggtgttctt ggtcagttac ttggatgctc tgagctttag tttcttggtg attacaatga
     1261 agatttgaat tacaggatgg ctttgaaaaa ataaacaaaa ctcccctttc tgtctgtcga
     1321 gaatgttgca cagggagtta cagaatgttc tcatgactga attgctttta aatttcacag
     1381 tgtgcctgca tttgaagtct tggaaatatc tccccaggaa gtatcttcag gcagactatt
     1441 gaagtcggcc tcatccccac cactgcatac atggctgaca gttttgaaaa aagagcagga
     1501 gttcctgggg gtgagtgagc ctcctccaac tttgactaga gtaagggttg ggtctagaaa
     1561 agaatattga gttgcatcaa ctgttttccc acttggattc atgagaggtg ttaggtcctt
     1621 taaaaaacat ggtagataaa gagttgacac taactgggtc cttttgggaa gagccagaag
     1681 catttcctca taaagacttt aaattgctag gacgagaatg gccaacagga gtgaaggatt
     1741 cataacttta tctttactta gatgtaaaga acaattactg atgttcaaca tgactacata
     1801 cataaaggcg catggagaaa agtattggcc ttccatgcat taggtagtgc ttgtatcaat
     1861 tcttatagtg gctagggtat cctggaaaat cttacgtgtg gatcatttct caggacagtc
     1921 taggacacta acgcagtttc tcatgtttgg cttctattat taaaaaatga tacaatctcg
     1981 ggaaaatttt tttgattttc atgaaattca tgtgtttttc tataggtaac acaaattctg
     2041 actgctatga tatgcctttg ttttggaaca gttgtctgct ctgtacttga tatttcacac
     2101 attgagggag acattttttc atcatttaaa gcaggttatc cattctgggg agccatattt
     2161 gtgagtatat atctataatt gtttctgaaa taacactgaa cataggtttt tctctttctc
     2221 agatctaacc agttgtttat tcccagtatt aagatgatat ttataattct taattataaa
     2281 tatatgtgag catatataac atagatatgc tcattaacaa caacaaaaga ttctttttac
     2341 aattaacggt gggttaaaca tttagcccac agttttatcc catgagaaac ctgaatctaa
     2401 tacaagttaa atgacttgcc taagggccac ttgactaata gtaattgaac ctaaactttc
     2461 agaatccaac tccaggaaca tacttctagc actattcatc aataaagtta tatgataaat
     2521 acatacaact ttatctgtca actaaaaata acaacagagg ctgggcatgg tggctcacac
     2581 ccgtaatccc agcactttgg gaggctgagg caggtggatc acctgaggtc aggagtttga
     2641 gaccagcctg accaacatgg tgaaacctca tctctactaa atataaaaaa ttagctgagt
     2701 gtgatagtgc atacctgtaa tccagctact taagaggctg aggcaggagg cttgtttgaa
     2761 cctggaaggc agaggttgca gtgagctgag attgtgccat tgcactccag cctgggcaat
     2821 aagtgcgaac tctgtctcaa aataataata ataataatag aaaataaagt tgtcttcatg
     2881 aaaaatgagg aaagagattg ctggggtgag aaacattaag atcaatgggc atatggtgac
     2941 cttctatgcc ctagaaactc ttttanggta ttttctcctg gtatctcttt tacncatcgt
     3001 tctatctgga aaaataggtg gatgagtgag ataataacgg tatatacttt ttaaaggtct
     3061 aattgacata tataaattgc aagtatttca gatgtcaatt tgctaacctt gacacacata
     3121 gacacacatg aaaacatcac cacattaata caatgtatgt atccatcatt ccaaaagctt
     3181 ccctgtgtat ctttgtaact ctttcttcct ccctccactc cttgtcctct cgttcccaag
     3241 aaaacattga tctgcttcct gtgaatataa attaacttac attttttaga gctttatata
     3301 agtatgttct ctttactgtt tgtcttcctt cgctgcacag ttattttgag attcttcaag
     3361 ttttttcttt atatcgatac ttcattcaca agaatatatt ttaattctag actatgtcac
     3421 attgactttg tcgtctgcta aatccttagt gctcagatga cttgttcagg actctccttg
     3481 aacctgtacc tctgttanat tgaaacttgt ctctactgtc tttttatttc aaacacagct
     3541 tattaggtgt ctctcaaccc atcaaacnca caatctgagt ctttaggaga ttgctttgaa
     3601 tttgtgctat tgacttatat ntatatnaaa tntgtaaatg tttggtaaaa atatcatcat
     3661 gtacnttttc ataattacgc tatntncaca tgatatatgt cagactctgg aaatatgcat
     3721 gccacagaca cgtgtttctt gcctaaaggg gctgatggaa gacncacata cnaatagacg
     3781 attgcagtag aatgagagtg gtggtctaan cagtacatgt cctgatgttg ctcggacagt
     3841 tactacncca agagtacccc ctgcattgtc agggttagca tctcctggaa gcctcatgta
     3901 aatgaagaat ttcatgctcc atccaggacc taatgaataa gaatctgcat tttagcaaga
     3961 ccctcatatg attcatatac actttttttt ttttttttta gatggagtct cactcttgtc
     4021 gcccaggctg gagtgcaatg gcatgatctt ggctcactgc aacctctgcc tcccgggttc
     4081 aagtgattct cctgtctcag cctccctagt agctgggact acaggtgcat gccacagtgg
     4141 ctggctaatt tttgtatttt tagtagagac agggtttcac cattttggtc aggctggtct
     4201 tgaactcatg acctccggtg attcccccgc ctcggcttcc caaagtgctg ggattacaga
     4261 catgagccac cacacccgcc ttattcgtat acncatttaa ttctgagaag cactctatag
     4321 aaaataagaa taagaaaata ttgggctcac aggtgacatt aataagtaac tttatcgagt
     4381 accccaaatt ttacctatgt ttggaagatg gggttaaaag gacacattga aaacaagaac
     4441 tcattgtggc ttttttttcc tcctttttga acagttttct atttctggaa tgttgtcaat
     4501 tatatctgaa aggagaaatg caacatatct ggtgagttgc ccgtttctgt ctttgtccat
     4561 ccttgaaaag ataagaagaa cagagtttta agagtcttaa gggaaacaca tctttgtctc
     4621 ctatattact tgtgaatgtg gatatatgat tttgtttcaa tctattttgt gtcctaaggc
     4681 tttttgcaac agaagttgga tatatcatta gaaacataaa ttgtaccatt taacatacat
     4741 gaagtttatg tttaccttga cgttcttcta aaaagtgtcc tacaccggca ttgtccttgt
     4801 aggcatattc acatgatcaa ataaaataat tagttttcaa ttaaggagaa tatttgagga
     4861 aagaccgtac gtgttcatgt ggttcctgaa ggcagtccag tgagaaagta atatatgctt
     4921 cattaaacaa tgcggacatt ttcagggttt ccctttttaa ccaaaatttg gaagcaatgt
     4981 ggaatttact ggatgcatcc agccctgaaa tgaagatagg tttattgaat gtgccagcaa
     5041 gtgcaggccc aggtctgagt gttcttcatt attatcaggt gagaggaagc ctgggagcaa
     5101 acactgccag cagcatagct gggggaacgg gaattaccat cctgatcatc aacctgaaga
     5161 agagcttggc ctatatccac atccacagtt gccagaaatt ttttgagacc aagtgcttta
     5221 tggcttcctt ttccactgta tgtatttttt tttgtgtggg aagactaaga ttctgggtcc
     5281 taatgtaagt aagaagccct cttctcctgt tccatgaaca ccatcctttt ctgtaacttc
     5341 tattacacag tatagtggtt ctgtaagttc acacagccca gggagatgct ggctgcccac
     5401 tcccctcaac ccaggcaaat tcctcggggt taaagttatc tactgcaagt gacgatctct
     5461 gggtttttct gtgcctgtgt ttgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtatgtgtca
     5521 ctttaaaagg actggtcaga tggtagggag atgaaaacag gagatgctat aagaaaataa
     5581 acttttgggg cgaataccaa tgtgactctt tttgtttgtc atttgttgct gttcaatagg
     5641 aaattgtagt gatgatgctg tttctcacca ttctgggact tggtagtgct gtgtcactca
     5701 caatctgtgg agctggggaa gaactcaaag gaaacaaggt agatagaagc ccgatataaa
     5761 atcttgaatg acaggttaac gaattggagc tttattcctt aaaatatggc ctgggttttc
     5821 tgaaacattt cttccagaaa atagtttctc caagttttat tactttggtt tacaaatctc
     5881 acatttaaat cacattttat accataagta gcacacattt cataatattc ctctgaatga
     5941 gggttgggat aataggactg atatgttaga aatgccttaa agtgtgtgga gcatgagaga
     6001 tggatgtaca gaaggcttgt gaggaaacca cccaggtatc tggccttgtt ttctgcccca
     6061 gaactagccg cctattcctg tttctgtttt attcctttgt ttcttgactt ttcctttcca
     6121 acttgctcta aaacctcagt tttctttcct ttctgattca tgactaccaa atgttttcac
     6181 ttgcctcacc cgtccattac acctttgata agaaccacca gaccttgtgc tcatgtactt
     6241 gcccatgtct gatggaagaa acatactctc tccatctgtc cactttcctg aggcattcaa
     6301 gtctagccac cttttaaaat cactctcctc caggctgggc acggtgtcac gcctgtaatc
     6361 tcagcacttt gtgaggctga ggagggcgga tcacttgaag tcaggagttc aaaaccagcc
     6421 tggccaaatg gcaaaaccaa atcttcttca attataacca aatcttaaac caaatctcta
     6481 ctaaaaaata caacaaaaca aaacaacaac aacaaaaaca gaaaaggaaa cattagccca
     6541 gcgtggtggc aggtacctga ggttccagat acttgggagg ctgaagcagg agaatcgctt
     6601 gagcccaaga gatggaggtt gcagtgagcc gagatcatgc cactgcacca cagccagggt
     6661 gacagagcca tacttcccag cacattggga ggccaaagct gaagaataat ttgaggtgag
     6721 gatttggaga ccagcctggc caacatggtg aaactccgtc tgtactaaaa atataaaact
     6781 tagtggggca tgggggcaca cacctgtaat ttcagctact taggaggctg aggcaggaga
     6841 attgcttgaa cccgggaggc ggaagttgca gtgagccaag atcgtggcca ctgcactcca
     6901 gcctgggtga catagtgaga ttctgtctca aaaaaaataa aagaaattta aaaaatcact
     6961 ctcttccaaa gatagataaa taagacagca gatatactaa ggaataacct caccaacttg
     7021 tcattgactg acatgatttc ttttggccca cttggccagc tagtctggtt tggttttctg
     7081 gaaatgaaag aaataatcag agtttaatga cagagagcgt gagacccaga aagacaaaag
     7141 tagatgaggt aagtctcttg agcgagactt ctagggatgg gaaatttgtg gtgattgata
     7201 tgaaatgatt tttcccttat caggttccag aggatcgtgt ttatgaagaa ttaaacatat
     7261 attcagctac ttacagtgag ttggaagacc caggggaaat gtctcctccc attgatttat
     7321 aagaatcacg tgtccagaac actctgattc acagccaagg atccagaagg ccaaggtttt
     7381 gttaaggggc tactggaaaa atttctattc tctccacagc ctgctggttt tacattagat
     7441 ttattcgcct gataagaata ttttgtttct gctgcttctg tccaccttaa tatgctcctt
     7501 ctatttgtag atatgataga ctcctatttt tcttgtttta tattatgacc acacacatct
     7561 ctgctggaaa gtcaacatgt agtaagcaag atttaactgt ttgattataa ctgtgcaaat
     7621 acagaaaaaa agaaggctgg ctgaaagttg agttaaactt tgacagtttg ataatatttg
     7681 gttcttaggg tttttttttt ttttagcatt cttaatagtt acagttgggc atgatttgta
     7741 ccatccaccc atacccacac agtcacagtc acacacacat atgtattact tacactatat
     7801 ataacttcct atgcaaatat tttaccacca gtcaataata catttttgcc aagacatgaa
     7861 gttttataaa gatctgtata attgcctgaa tcaccagcac attcactgac atgatattat
     7921 ttgcagattg acaagtagga agtggggaac ttttattaag ttactcgttg tctggggagg
     7981 taaataggtt aaaaacaggg aaattataag tgcagagatt aacatttcac aaatgtttag
     8041 tgaaacattt gtgaaaaaag aagactaaat taagacctga gctgaaataa agtgacgtgg
     8101 aaatggaaat aatggttata tctaaaacat gtagaaaaag agtaactggt agattttgtt
     8161 aacaaattaa agaataaagt tagacaagca actggttgac taatacatta agcgtttgag
     8221 tctaagatga aaggagaaca ctggttatgt tgatagaatg ataaaaaggg tcgggcgcgg
     8281 aggctcacgc ctgtaatccc agccctttgg gaggccgagg tgggcagatc acgaagtcag
     8341 tagtttgaga ccagcctggc caacatagtg aaaccccgtc tctactaaaa atacaaaaaa
     8401 aaaattagct gggtgtggtg gcagtcacct gtagtcccag ctacttggga ggatgaggca
     8461 ggagaatcgc ttgaacctgg gaggcggagg ttgcagtgag ccgagatcgc accagtgcac
     8521 tccagccttg gtgacaatgg gagactccat ctcaaaaaaa aaaaaaaaaa aaaaaagata
     8581 aaaagtcaga aatctgaaaa gtggaggaag agtacaaata gacctaaatt aagtctcatt
     8641 ttttggcttt gattttgggg agacaaaggg aaatgcagcc atagagggcc tgatgacatc
     8701 caatacatga gttctggtaa agataaaatt tgatacacgg tttggtgtca ttataagaga
     8761 aatcattatt aaatgaagca agttaacact ctaagagaat tattttgaga tagaagtgaa
     8821 gctaagctaa acttcacatg cctataattg gagggaaaaa ctaaggataa aatctagcct
     8881 agaagataca ataattagtc ataaacatgc attgtgaaac tgtagagagc aggtagccca
     8941 aaatagagaa agattagata aagagaaaat aagtatccat cagagacagt atctctaggc
     9001 ttgggcaaga gaaaagtcca cagtgataag caactccacc taaggcatga atatgcggca
     9061 gagaaaacag caatagtgaa tgaatgcaaa aggtgctgag caaattccac acatgagtat
     9121 tgtgcatgag taaatgaata aaacatttgc aaagaccttt agagaaagag aatgggagca
     9181 tatgtgcgaa ataagatagt tgattatgaa tagaaggtag tgaagaaaag caagctaaga
     9241 aaaaattctg tttataaaag aaggaaaaga tagtttatgt ttttagccta agtataagag
     9301 tcctacagat ggactgaaaa aaatcagtct gagagtatta gtcacaatta atgaaataat
     9361 tacattttat gtattgagga tgccaagatt aaaaggtgac aggtagatgt taatttccct
     9421 agattgtgaa agtgatcacg acaatcacac aacaaataat taagtgactt ggtatgcttt
     9481 atttaattgt agggcctgag gttttccatt ctcatttttc taaaatacaa ttttgtttct
     9541 ccaaatttga cagcagaata aaaaccctac cctttcactg tgtatcatgc taagctgcat
     9601 ctctactctt gatcatctgt aggtattaat cacatcactt ccatggcatg gatgttcaca
     9661 tacagactct taaccctggt ttaccaggac ctctaggagt ggatccaatc tatatcttta
     9721 cagttgtata gtatatgata tctcttttat ttcactcaat ttatattttc atcattgact
     9781 acatatttct tatacacaac acacaattta tgaatttttt ctcaagatca ttctgagagt
     9841 tgccccaccc tacctgcctt ttatagtacg cccacctcag gcagacacag agcacaatgc
     9901 tggggttctc ttcacactat cactgcccca aattgtcttt ctaaatttca acttcaatgt
     9961 catcttctcc atgaagacca ctgaatgaac accttttcat ccagccttaa tttcttgctc
    10021 cataactact ctatcccacg atgcagtatt gtatcattaa ttattagtgt gcttgtgacc
    10081 tccttatgta ttctcaatta cctgtatttg tgcaataaat tggaataatg taacttgatt
    10141 tcttatctgt gtttgtgttg gcatgcaaga tttaggtact tatcaagata atggggaatt
    10201 aaggcatcaa taaaatgatg ccaaagacca agagcagttt ctgaagtcct ccttttcatc
    10261 agctctttat caaacagaac actctataaa caacccatag ccagaaaaca ggatgtagga
    10321 acaatcacca gcacactcta taaacaaccc atagccagaa aacagaatgt aaggacaatc
    10381 accagccatc ttttgtcaat aattgatgga atagagttga aaggaactgg agcatgagtc
    10441 atatttgacc agtcagtcct cactcttatt tacttgctat gtaaacttga gaaagctttt
    10501 ttctctttgt gaacctcagg ttttacatct gaaaatgaga aatttggaac aaaagattcc
    10561 taactggtct ttctgttccc atattctgtg atttttcaat atttaggatt tttggtaatc
    10621 acaattactt agtttgtggt tgagatagca acacgaatca gaactatttg gtggacatat
    10681 tttcaaagga gtagctctcc actttgggta aagaagtgat gcnggtcgtg gtggctcacg
    10741 cctgtaatcc cagcacttta gggaggccaa ggcgggtgga tcacgaggtc aggagatcga
    10801 gaccatcctg gctaacacgg tgaaaccccg tctctactaa aaaatacaaa aaattagcca
    10861 ggcgtggtgg cgggcgcctg tagtcccacg tactcgggag gctgaggcag gagaatggca
    10921 tgaaccaggg aggcggagct tgccgtgagc cgagatagcg ccactgcagt ccctcctggg
    10981 caaaagagca agactgcgtc tcaaaaaaaa aaaaaaaaaa aaaaaaagaa gtgtgtggag
    11041 tagcaggaca cctgcaacaa taatattttt ctaaatccct ctgaaaaatg ctaatcaaag
    11101 ggtttttttc ctaaaaattg tcttagaaat aaaatttccc ctttgggaga ccgaggctgg
    11161 cagatcacga ggtcaggaga tagagaccac ggtgaaaccc cgtctctact aaaaatacta
    11221 aaaattagcc ggggngtggt ggtgggtaca cctgtagtcc cagctacttg gaggctgagg
    11281 ctggagaatc acgtgaac
//