From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Simian immunodeficiency virus (32H reisolate of SIVmac251 from
Date: 26 Jan 93 05:51:29 GMT
Distribution: bionet
Checksum: 55208 5

LOCUS       SIV2256MO    1122 bp ss-RNA             VRL       25-JAN-1993
DEFINITION  Simian immunodeficiency virus (32H reisolate of SIVmac251 from
            I225) gp120 (V2, V4) RNA, partial cds's.
ACCESSION   M92725
KEYWORDS    .
SOURCE      Simian immunodeficiency virus 6 months post infection cDNA to
            genomic RNA.
  ORGANISM  Simian immunodeficiency virus
            Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
            Retroviridae.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Almond,N.M., Jenkins,A.R., Slade,A., Heath,A.B., Cranage,M. and
            Kitchin,P.A.
  TITLE     Population sequence analysis of a simian immunodeficiency virus
            (32H re-isolate of SIVmac251): A virus stock used for international
            vaccine studies
  JOURNAL   AIDS Res. Hum. Retroviruses 8, 77-88 (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1122)
  AUTHORS   Almond,N.M., Jenkins,A.R., Heath,A.B., Taffs,F. and Kitchin,P.A.
  TITLE     The genetic evolution of the envelope gene of simian
            immunodeficiency virus in cynomolgus macaques infected with a
            complex virus pool
  JOURNAL   Virology 191, 996-1002 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     variation       replace(123,"")
                     /citation=[2]
                     /note="'a' in variation"
     misc_feature    1122
                     /note="end of gp120"
     CDS             1..1122
                     /partial
                     /note="Partial sequence of the PCR product of SIV gp120
                     obtained bydirect sequence analysis. The region of
                     sequence extendsfrom the end of the V1 region to the
                     gp120:gp41 junction"
                     /product="gp120"
                     /codon_start=1
                     /translation="KIDMVNETSSCIAQNNCTGLEQEQMISCKFNMTGLKRDKTKEYN
                     ETWYSTDLVCEQGNSTDNESRCYMNHCNTSVIQESCDKHYWDTIRFRYCAPPGYALLR
                     CNDTNYSGFMPKCSKVVVSSCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIIS
                     LNKYYNLTMKCRRPGNKTVLPVTIMSGLVFHSQPINDRPKQAWCWFGGKWKDAIKEVK
                     QTIVKHPRYTGTNNTDKINLTAPGGGDPEVTFMWTNCRGEFLYCKMNWFLNWVEDRNT
                     TNQKPKEQHKRNYVPCHIRQIINTWHKVGKNVYLPPREGDLTCNSTVTSLIANIDWTD
                     GNQTNITMSAEVAELYRLELGDYKLVEITPIGLAPTDVKR"
     CDS             49..277
                     /gene="V2"
                     /partial
                     /product="gp120"
                     /codon_start=1
                     /translation="CTGLEQEQMISCKFNMTGLKRDKTKEYNETWYSTDLVCEQGNST
                     DNESRCYMNHCNTSVIQESCDKHYWDTIRFRY"
     CDS             784..874
                     /gene="V4"
                     /partial
                     /product="gp120"
                     /codon_start=1
                     /translation="CKMNWFLNWVEDRNTTNQKPKEQHKRNYVP"
BASE COUNT      398 a    179 c    252 g    293 t
ORIGIN      
        1 aaaatagaca tggtcaatga gactagttct tgtatagctc agaataattg cacaggcttg
       61 gaacaagagc aaatgataag ctgtaaattc aacatgacag ggttaaaaag agacaagaca
      121 aaggagtaca atgaaacttg gtactctaca gatttggttt gtgaacaagg gaatagcact
      181 gataatgaaa gtagatgcta catgaatcac tgtaacactt ctgttatcca agagtcttgt
      241 gacaaacatt attgggatac tattagattt aggtattgtg cacctccagg ttatgctttg
      301 cttagatgta atgacacaaa ttattcaggc tttatgccta aatgttctaa ggtggtggtc
      361 tcttcatgca caaggatgat ggagacacag acttctactt ggtttggctt taatggaact
      421 agagcagaaa atagaactta tatttactgg catggtaggg ataataggac tataattagt
      481 ttaaataagt attataatct aacaatgaaa tgtagaagac caggaaataa gacagtttta
      541 ccagtcacca ttatgtctgg attggttttc cactcacaac caatcaatga taggccaaag
      601 caggcatggt gttggtttgg aggaaaatgg aaggatgcaa taaaagaggt gaagcagacc
      661 attgtcaaac atcccaggta tactggaact aacaatactg ataaaatcaa tttgacggct
      721 cctggaggag gagatccgga agttaccttc atgtggacaa attgcagagg agagttcctc
      781 tactgtaaaa tgaattggtt tctaaattgg gtagaagata ggaatacaac taaccagaag
      841 ccaaaggaac agcataaaag gaattacgtg ccatgtcata ttagacaaat aatcaacact
      901 tggcataaag taggcaaaaa tgtttatttg cctccaagag agggagacct cacgtgtaac
      961 tccacagtga ccagtctcat agcaaacata gattggactg atggaaatca aactaatatc
     1021 accatgagtg cagaggtggc agaactgtat cgattggaat tgggagatta taaattagta
     1081 gagatcactc caattggctt ggcccccaca gatgtgaaga gg
//