From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse histidase locus histidine ammonia-lyase mRNA, complete cds.
Date: 29 Dec 92 19:50:08 GMT
Distribution: bionet
Checksum: 28816 5

LOCUS       MUSHAL       2281 bp ss-mRNA            ROD       09-DEC-1992
DEFINITION  Mouse histidase locus histidine ammonia-lyase mRNA, complete cds.
ACCESSION   L07645
KEYWORDS    histidase; histidine ammonia-lyase.
SOURCE      Mus musculus (strain C57BL/6J, sub_species domesticus) (library:
            lambda ZAP; Stratagene) 6-8 weeks liver cDNA to mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2281)
  AUTHORS   Taylor,R.G., Grieco,D., Clarke,G.A., McInnes,R.R. and Taylor,B.A.
  TITLE     Identification of the mutation in murine histidinemia (his) and
            genetic mapping of the murine histidase locus (Hal)
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            <1..2181
     polyA_signal    2163..2170
     polyA_site      2181
                     /evidence="EXPERIMENTAL"
     CDS             48..2021
                     /EC_number="4.3.1.3"
                     /product="histidine ammonia-lyase"
                     /codon_start=1
                     /translation="MPRYTVHVRGEWLAVPCQDGKLTVGWLGREAVRRYMKNKPDNGG
                     FTSVDEVQFLVHRCKGLGLLDNEDELEVALEDNEFVEVVIEGDVMSPDFIPSQPEGVF
                     LYSKYREPEKYIALDGDSLSTEDLVNLGKGRYKIKLTSIAEKKVQQSREVIDSIIKER
                     TVVYGITTGFGKFARTVIPANKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVL
                     AKGYSGISLETLKQVIEAFNASCLSYVPEKGTVGASGDLAPLSHLALGLIGEGKMWSP
                     KSGWADAKYVLEAHGLKPIVLKPKEGLALINGTQMITSLGCEALERASAIARQADIVA
                     ALTLEVLKGTTKAFDTDIHAVRPHRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQ
                     DAYTLRCCPQVHGVVNDTIAFVKDIITTELNSATDNPMVFASRGETISGGNFHGEYPA
                     KALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVS
                     ESKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVVEHVEQVLAIELLAACQGIEF
                     LRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLLDQKVWEVAAPYIEKYR
                     MEHIPESRPLSPTAFSLESLRKNSATIPESDDL"
BASE COUNT      563 a    564 c    624 g    530 t
ORIGIN      
        1 cttggttaca gtggcctgct gctcagaagg gctatagcat ctgagccatg cctaggtaca
       61 cagtgcacgt gcgtggggaa tggctggcgg tgccctgtca ggatgggaag ctcactgttg
      121 gctggctggg ccgtgaggct gtgcgacgct acatgaagaa caaaccggac aatggtggct
      181 tcacttcggt ggatgaagtg caattccttg tgcatcggtg caagggcctg ggcctgctgg
      241 acaatgagga cgagctggag gtggccttag aggacaatga gttcgtagaa gtggtgattg
      301 aaggtgatgt gatgtctcct gatttcattc cgtcgcagcc agaaggagtt ttcctataca
      361 gcaaataccg ggagcctgaa aaatacattg ccctagatgg ggacagtctg agcacagagg
      421 atctggtcaa cctgggcaag ggacgttaca agataaagct cacttcaatt gctgagaaga
      481 aagtgcagca gtcccgggag gtcatcgaca gcatcatcaa agaaagaaca gttgtttatg
      541 gcatcaccac aggttttgga aaatttgcta gaactgtaat ccctgccaat aagctacagg
      601 agcttcaagt caacttagtc cgttcccatt cttcaggtgt tgggaaacca ctcagtcctg
      661 agaggtgtcg gatgctcttg gctttgagga tcaacgtctt agccaaaggt tacagtggga
      721 tttccttgga gacgctgaaa caagttattg aagcatttaa tgcctcctgc ctgtcctatg
      781 ttccagagaa aggaactgtg ggtgccagcg gagaccttgc cccactctct catcttgctc
      841 tggggctcat cggagaagga aagatgtggt ccccgaagag tggctgggca gatgctaaat
      901 atgttctaga agcccatgga ctgaaaccaa ttgtcttgaa accaaaagaa ggcctggcac
      961 tcatcaatgg gacacagatg atcacttccc tgggctgtga agccctggag cgagccagcg
     1021 ccattgcccg gcaagctgat attgtggctg ccttgaccct ggaggtgctg aagggcacca
     1081 ccaaagcctt cgataccgac atccatgctg tccgacctca ccgtgggcaa attgaagttg
     1141 ctttccgatt ccggtccctc ctggactcgg atcaccaccc atcagaaatc gcagaaagcc
     1201 acaggttctg cgatcgtgtt caggacgcgt acaccttacg ctgctgtcca caggtccacg
     1261 gtgtggtgaa cgacacaata gcctttgtga aggacatcat cactacagaa ctgaacagcg
     1321 ccacagacaa tcctatggtc tttgccagtc gaggggagac aatttcagga ggaaacttcc
     1381 atggtgaata cccagccaaa gccctggact atttggccat tggtgtccat gaacttgcgg
     1441 caattagtga aagaagaatc gaaaggctgt gtaatccttc cctcagcgag ctgcctgcct
     1501 tcctggtggc tgaaggaggt ctcaattctg ggttcatgat agcccactgc accgcagcag
     1561 ccctggtgtc tgagagcaag gctctgtgcc acccttcatc tgtggactca ctctcgacca
     1621 gtgctgctac agaagaccac gtctccatgg gaggatgggc agccaggaaa gccctcaggg
     1681 tcgtcgagca cgtggaacaa gtgctagcca ttgagcttct cgcggcctgc cagggtatag
     1741 agtttctgcg ccccctgaaa acaaccactc cgctggagaa ggtgtacgac ctggtgcgct
     1801 ccgtagtaag gccctggata aaagatcgct tcatggcccc ggacattgag gcagcacaca
     1861 ggttgcttct tgaccaaaag gtttgggagg ttgccgcacc gtacatcgag aaatacagaa
     1921 tggagcacat tccggaatcc agaccgcttt ctccaacagc gttttcacta gaatctctcc
     1981 gaaagaactc agccacaatc ccagagtctg acgatcttta acgggcttcc tcgaggacag
     2041 gcacatcaga tgggcctgag cttagcacag cactggtgtg ttgatggaga gagagtctca
     2101 ggaactgcct gtaatgtgta aaactcatct cttttcaaac atactctgga taggccatgg
     2161 cagcaatgca gtggctgaac ccagagccct gatcttgttt tcttgttact atggtttgag
     2221 gagtactggg tgccttgtgg ttgtggagtt gtctttcttg ataatataaa caggctactt
     2281 a
//