From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: SP-A=pulmonary surfactant-associated protein [mice, DBA/2J,
Date: 27 Jan 93 05:57:47 GMT
Distribution: bionet
Checksum: 65222 8

LOCUS       S118740      4942 bp    DNA             ROD       14-JAN-1993
DEFINITION  SP-A=pulmonary surfactant-associated protein [mice, DBA/2J,
            Genomic, 4942 nt]
ACCESSION   S48768
KEYWORDS    .
SOURCE      mice DBA/2J
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 4942)
  AUTHORS   Korfhagen,T.R., Bruno,M.D., Glasser,S.W., Ciraolo,P.J.,
            Whitsett,J.A., Lattier,D.L., Wikenheiser,K.A. and Clark,J.C.
  TITLE     Murine pulmonary surfactant SP-A gene: cloning, sequence, and
            transcriptional activity.
  JOURNAL   American Journal of Physiology 263, L546-54 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 118740] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 1.  The authors begin their numbering
            at -1402.  Zero is not present in the numbering.
FEATURES             Location/Qualifiers
     mRNA            join(1403..2250,2443..2562,3256..3333,3686..4092)
     CDS             join(2079..2250,2443..2562,3256..3333,3686..4062)
                     /note="pulmonary surfactant-associated protein;  For the
                     protein sequence (NCBI gibbsq 118741):  Method: conceptual
                     translation supplied by author.  This sequence comes from
                     Fig. 1."
                     /product="SP-A"
                     /codon_start=1
                     /translation="MSLGSLAFTLFLTVVAGIKCNGTEVCAGSPGIPGTPGNHGLPGR
                     DGRDGIKGDPGPPGPMGPPGGMPGLPGRDGLPGAPGAPGEHGDKGEPGERGLPGFPAY
                     LDEELQTASYEIKHQILQTMGVLSLQGSMLSVGDKVFSTNGQSVNFDTIREMCTRAGG
                     HIAAPRNPEENEAIASITKKYNTYPYLGVIEGQTPGDFHYLDGASVNYTNWYPGEPRG
                     RGKEKCVEMYTDGKWNDKGCLQYRLAICEF"
BASE COUNT     1193 a   1132 c   1209 g   1408 t
ORIGIN      
        1 aagctttcca gggtctttct ttgtgtgctc agcattgccg ctcttccctc tgcttgttag
       61 ttgcagccat ctgagtggct ggatagcggc atcctattag agtgttggtt tgtatttccc
      121 tagttgatgg tgttgttgaa cccctttgga tgtgtcagtt tgtatatctc ccttgcatgt
      181 ttgtgtgaat acggacatgc ctgtgaccct gcacacgtac ggaagccgga gacaaccttg
      241 aatgtcactc ctcaccgccc accttgtttc acgtggggtc tgcattgcca ctgagcaccg
      301 cagctgggtg acaggagatt caggaggttc tccagggtcc atttcttgtc tggacagagg
      361 acagctggga cacaaggtgc cttcttcatg tcctgggggg caaatctcag gccctcacac
      421 ttgcatggca aattgcttta ctcactgaac cagctctttg ggcccgtttt cacactttat
      481 tttattctga aaaatatttt taattctttt gttcctcttt ttacctttat ttgattttgt
      541 ttgtttttat tttgtaaaca gatttttttt tgtgggtgtt tttgctctgt tttcttcctc
      601 ttttctcctc ctctttgttc cccccccccc ccccgcttta ttattattat tattgttttt
      661 tttttcagtc catttgttac ccacctcctg gtctaccctc ccacagttcc tcactcctct
      721 tgccctcctg atgtccctcc cctcgctgcc atcccccttc ccctgccagg cctcccattc
      781 cctggggcct cacgtctctc aagggataga catgtcttct ctcactgagg ccagatcagg
      841 cagtcctttg ctttatatgt gtcgggtggg ggtgggggtg gggatcccca tgctttttaa
      901 tttaatcttg cttctttatc tttttctttt ccctgatctc cctttattta atcttcttgt
      961 tattattccc agtattttta atccattttc aacgttatta tctcctttct gcttctttcc
     1021 tatggccgtt ggtaatagag ttatgacaga gctatagttt tggttgttct gatgttttgc
     1081 tttcttttct gaatggcagt gcatcttcac caggacctcg gaaaggcttt cattttgtgc
     1141 tgctggccac aagtgttaat ttagaataga gggtgacctt gacaagagag agattccctt
     1201 cccacacact tgggagtttg ccttctgtgg ttctgtgcca ccctcaaggt tctaagtgct
     1261 cttcttgtta agtgctctga aggaacctga gctgtgtaca cacgatggct gcttcctgtc
     1321 cggccctcct ttgtgatagg ggctctgagg gtggggaaag ctgtcagctt acatatctat
     1381 aaaggatgcc gtccacttgt ccactttgac tcggaggcag acatccacac agcttgcagg
     1441 ctctgtgtgc gggtgagctt agccaccagt ccctgggtat ccaccagtgt atgggtttct
     1501 ggcagtaaga gccacacact aattgagggc tgactgggta gaaaggtact gcgtacgact
     1561 aacagtttag caggactacg tacccttctc gtttctgttt atctgagaac ccaaaacaga
     1621 ataacttaaa atattgaggg acaggtagag taacctggtg actgtacatc tcctaacaga
     1681 caaccctgtt aagattgtct acagagcaca gcaggattag ctaaggtcag agaggtacag
     1741 tagattccct ggggtgacac agctaagtta taatagataa gaatctcctg aggactcagg
     1801 cctctgactc acctgagctc tcctcctcta ttcagggatc tgaagttgga ggcctgcagt
     1861 gtgattgggt aagacaccag agatgctggg gatttctgac tggggatagt ttaggtcttc
     1921 ttagtattct cggctgtacc tgcctgtcat gttcttctgt ggttcctggg tcctgcaaag
     1981 tgtagcagga atgggggtgt caaaggagag ctatgttaat gctacagatt ggctggtggc
     2041 ccttctgtcc tgcaggagaa accactggta cagtagccat gtcactaggc tctttggcct
     2101 tcaccctctt cttgactgtt gttgctggca tcaagtgcaa tgggacagaa gtttgtgccg
     2161 gaagccctgg gatccctggc actcccggaa accatggttt gcccggcaga gatgggagag
     2221 atggtatcaa aggagaccct ggacctccag gtactgtatg ggagaaccca tccttagctc
     2281 agggataggg acctgttttc tgggtgacca tctgtctagc tgaagggatt tttctggagt
     2341 cctcgggcta gagcatgtgt cttcaaagtt cctgtggatg gacaagagag tctcccacat
     2401 gctaatggag gtccatatat ctgtgttctc ttcactcggt aggtcccatg ggccctcctg
     2461 gaggaatgcc aggtcttcct gggcgcgatg ggctgcctgg agcccctggt gcacctggag
     2521 aacatggaga caagggagag cctggagaaa gggggcttcc aggtgagcag gaccagagtc
     2581 agtagaaagt agtgatgtca catgagggat ggaaggaagg gttcaagaca cactgctaag
     2641 cctaagtaag aaagtatgaa tttgaaaaga aaaaccacaa gcatttgaac ttatttcaga
     2701 gattgacaag catcgtggct actgattggg agacacatat tgtcctgtag gggaacagaa
     2761 ttagcattgg gaagcctagg gttccttctt agggttgagg ctgtggtcat cctaaaaagt
     2821 agacagggct atatggactg gaatccaggc agacagttgt gatcaggaat cccacacgat
     2881 gacagaagtt ccagggtatg aataagtcta gtggcctatc tggagagttc agaggtcatc
     2941 attgttgatc ttggtagagt acgtgggagg gggtcttttt cataggcaag aataacacat
     3001 atatatggac acgaagggcc agtcaaagga tacggaagag tagagcagga aagctgagca
     3061 ggttcaagct acactaagag atgggtgtgt atgagtacag taggtcgctt tctgggctct
     3121 tgaaactggc gtgtgggctc tcagtacagc attagacgac agaactccag cctggcagct
     3181 ggcagaatac ctgtctggta gcaagtagag ctctttggtg gattgtccca tcctggacgt
     3241 gtatgttctc tacagggttt ccagcttacc tggatgagga gcttcagact gcatcctacg
     3301 agatcaaaca tcagattctg caaacaatgg gaggtaaggg gactgcttgg ggagggggga
     3361 tctcaccaag cacacatctc tcagtactcc cctctcacag tcagtaccag gatccagaac
     3421 ataaatggct agcaaatgag tgtgacatag ggctggagaa ggatttcctc ccgatgtcac
     3481 tgggaagcat gaaagtgagg atgcctgcaa taagtaattg ttaggtgaat gagaacagag
     3541 agatggattt taaaactggg cttggaacag gaagggaaaa cactgagaaa agcagagatg
     3601 gagagattgt gtggagaaag cttaagtcag tggagtaaga tggagaaaga ggggtccatg
     3661 gcctaaccca gactcctttg cttagtcctc agcttgcaag gatccatgct gtcagtgggg
     3721 gataaagtct tttccaccaa tgggcagtca gtcaactttg ataccattag agagatgtgt
     3781 accagagccg gtggccacat tgctgccccg aggaatcctg aggagaacga ggccatcgca
     3841 agcattacaa agaagtacaa cacctatccc tacttaggtg tgattgaagg ccagactcct
     3901 ggagacttcc actacctgga tggggcttct gtgaactaca ccaactggta cccaggagag
     3961 cccaggggtc ggggcaaaga gaaatgtgta gaaatgtata cagatgggaa atggaatgat
     4021 aagggctgcc tgcagtaccg gctggccatt tgtgaatttt gatcaagcaa ttagatgaaa
     4081 agataaaact tcacactgtc tttaagcctc tatcttgatg atccatctgg tctgtaagac
     4141 ctgtaactac ctttcaagca aatttacttg tggccatcag aattataagc atccttagtt
     4201 acgccatctc ccacatggct tctaaactct tctccatatt cattagtaat cctgagtgtc
     4261 ccctagagtc ccatctgagc attcaactca aggcagccac tgtcaacctt gattttcatc
     4321 aggagatcga tggagactcc tttttcctca ctttgtccag tcttcactta taaattgtgg
     4381 ccatggaaga accctctaaa ttacatagaa agtgcctgct cctggaccct tcaacccttc
     4441 ttctgcagct catggtccca agatttaaaa gtccaggtta aatataaaag atagccatag
     4501 ggaatttctg ggaaatacct agtatatgga tgtaggccac attgagtgtc ctctgtatac
     4561 ctgctttcaa ggcaaacacg gtgtctaaga agccagagaa ccaggtaggg ccacagcaca
     4621 gtactgggga aacataacct ccctggttgg catatatggc ctcttccttg gatctggatc
     4681 ttgacctaat agcagccacc ctgagtttag agagaatcac ctttccagcc cagaccctaa
     4741 ctcaagtaat ttcctgctaa caaacataac cttcgtccac tttacatcac tgaggcatac
     4801 caactgctct cttttcgcct ctcatgaact caatcaacta ttccattaaa gtcagcttca
     4861 tcccagatgt tagtctgtct tccggtaagc tttgagctaa cttttctttg agcttatttc
     4921 tttactatgg tatgcaaata aa
//