From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Glutamic acid decarboxylase large isoform [human, frontal cortex,
Date: 27 Jan 93 06:00:55 GMT
Distribution: bionet
Checksum: 40821 7

LOCUS       S119748      3241 bp    mRNA            PRI       19-JAN-1993
DEFINITION  Glutamic acid decarboxylase large isoform [human, frontal cortex,
            mRNA, 3241 nt]
ACCESSION   S49758
KEYWORDS    .
SOURCE      human frontal cortex
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 3241)
  AUTHORS   Kelly,C.D., Edwards,Y., Johnstone,A.P., Harfst,E., Nogradi,A.,
            Nussey,S.S., Povey,S. and Carter,N.D.
  TITLE     Nucleotide sequence and chromosomal assignment of a cDNA encoding
            the large isoform of human glutamate decarboxylase.
  JOURNAL   Ann. Hum. Genet. 56 ( Pt 3), 255-265 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 119748] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 2.  Map location: 2.
FEATURES             Location/Qualifiers
     CDS             184..1965
                     /note="GAD67;  For the protein sequence (NCBI gibbsq
                     119749):  Method: conceptual translation supplied by
                     author.  This sequence comes from Fig. 2."
                     /product="Glutamic acid decarboxylase large isoform"
                     /codon_start=1
                     /translation="MASSTHLSATSSNAEPDPNTTNLRPTTYDTWCGVAHGCTRKLGL
                     KICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDL
                     LPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDH
                     PESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLNSTANTNMFTYEIA
                     PVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMA
                     AVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKG
                     YVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGI
                     ERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDK
                     AIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPE
                     HTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANLFR
                     MVISNPAATQSDIDFLIEEIERLGQDL"
BASE COUNT      916 a    709 c    775 g    841 t
ORIGIN      
        1 tccgcagcag cctggaggtg acgccgggca gattacgcct gtcagggccg agccgaacgg
       61 atcgctgggc gctgtgcaga ggaaaggcgg gagtgcccgg ctcgctgtcg cagagccgag
      121 cctgtttctg cgccggacca gtcgaggact ctggacagta gaggccccgg gacgaccgag
      181 ctgatggcgt cttcgaccca tttgtccgca acctcctcga acgcggaacc ggaccccaat
      241 accactaacc tgcgccccac aacgtacgat acctggtgcg gcgtggccca cggatgcacc
      301 agaaaactgg gcctcaagat ctgcggcttc ttgcaaagga ccaacagcct ggaggagaag
      361 agtcgccttg tgagtgcctt caaggagagg caatcctcca agaacctgct ttcctgtgaa
      421 aacagcgacc gggatgcccg cttccggcgc acagagactg acttctctaa tctgtttgct
      481 agagatctgc ttccggctaa gaacggtgag gagcaaaccg tgcaattcct cctggaagtg
      541 gtggacatac tcctcaacta tgtccgcaag acatttgatc gctccaccaa ggtgctggac
      601 tttcatcacc cacaccagtt gctggaaggc atggagggct tcaacttgga gctctctgac
      661 caccccgagt ctctggagca gatcctggtt gactgcagag acaccttgaa gtatggggtt
      721 cgcacaggtc atcctcgatt tttcaaccag ctctccactg gattggatat tattggccta
      781 gctggagaat ggctgaactc aacggccaat accaacatgt ttacatatga aattgcacca
      841 gtgtttgtcc tcatggaaca aataacactt aagaagatga gagagatagt tggatggtca
      901 agtaaagatg gtgatgggat attttctcct gggggcgcca tatccaacat gtacagcatc
      961 atggctgctc gctacaagta cttcccggaa gttaagacaa agggcatggc ggctgtgcct
     1021 aaactggtcc tcttcacctc agaacagagt cactattcca taaagaaagc tggggctgca
     1081 cttggctttg gaactgacaa tgtgattttg ataaagtgca atgaaagggg gaaaataatt
     1141 ccagctgatt ttgaggcaaa aattcttgaa gccaaacaga agggatatgt tcccttttat
     1201 gtcaatgcaa ctgctggcac gactgtttat ggagcttttg atccgataca agagattgca
     1261 gatatatgtg agaaatataa cctttggttg catgtcgatg ctgcctgggg aggtgggctg
     1321 ctcatgtcca ggaagcaccg ccataaactc aacggcatag aaagggccaa ctcagtcacc
     1381 tggaaccctc acaagatgat gggcgtgctg ttgcagtgct ctgccattct cgtcaaggaa
     1441 aagggtatac tccaaggatg caaccagatg tgtgcaggat acctcttcca gccagacaag
     1501 cagtatgatg tctcctacga caccggggac aaggcaattc agtgtggccg ccacgtggat
     1561 atcttcaagt tctggctgat gtggaaagca aagggcacag tgggatttga aaaccagatc
     1621 aacaaatgcc tggagctggc tgaatacctc tatgccaaga ttaaaaacag agaagaattt
     1681 gagatggttt tcaatggcga gcctgagcac acaaacgtct gtttttggta tattccacaa
     1741 agcctcaggg gtgtgccaga cagccctcaa cgacgggaaa agctacacaa ggtggctcca
     1801 aaaatcaaag ccctgatgat ggagtcaggt acgaccatgg ttggctacca gccccaaggg
     1861 gacaaggcca acttattccg gatggtcatc tccaacccag ccgctaccca gtctgacatt
     1921 gacttcctca ttgaggagat agaaagactg ggccaggatc tgtaatcatt ccttcgcaga
     1981 accataagct ttatgggaat ggccttttcc ctctggcact tccagaacaa acctctatat
     2041 gttgctgaaa cacacaggcc atttatttga gggaaacata atatcttgaa gatatgttaa
     2101 accttactta agcttgtttg ttctagttag caggaaatag tgttcttttt aaaaagttgc
     2161 acattaggaa cagagtatat atgtacagtt atacatacct ctctctatat atacatgtat
     2221 agtgagtgtg gcttagtaat agatcacggc atgtttcccg ctccaagaga attcacttta
     2281 ccttcagcag ttaccgagga gctaaacatg ctgccaacca gcttgtccaa caactccagg
     2341 aaaactgttt ttcaaacgcc atgtcctagg ggccaaggga aatgctgttg gtgagaatcg
     2401 acctcactgt cagcgtttct ccacctgaag gtgatgatgg atgagaaaac acaccaatga
     2461 cagtcacacc tcccattagt atctgttagg ggaaatagta gcagagtcat tgttacaggt
     2521 gtactatggc tgtattttta gagattaatt tgtgtagatt gtgtaaattc ctgttgtctg
     2581 accttggtgg tgggaggggg agactatgtg tcatgatttc aatgattgtt taattgtagg
     2641 tcaatgaaat atttgcttat ttatattcag agatgtacca tgttaaagag gcgtcttgta
     2701 ttttcttccc atttgtaatg tatcttattt atatatgaag taagttctga aaactgttta
     2761 tggtattttc gtgcatttgt gagccaaaga gaaaagatta aaattagtga gatttgtatt
     2821 tatattagag tgcccttaaa taatgattaa gcatttactg tcgttaagag aattctaaga
     2881 tggtacataa agtcatatat atggaaatcc tgttacttaa atagcatctg ctcttctctt
     2941 acgctctctg tctggctgta cgtctggtgt gctcaatgct tttctagcaa ctgttggata
     3001 ataactagat ctcctgtaat tttgtagtag ttgatgacca atctctgtga ctcgcttagc
     3061 tgaaacctaa ggcaacattt ccgaagacct cctgaagatc tcagataaag tgaccaggct
     3121 cacaactgtt tttgaagaag ggaaattcac actgtgcgtt ttagagtatg caagaagaat
     3181 ataaataaat aaaaatattc tccatggaga atttgaacaa aaaaaaaaaa aaaaaaaaaa
     3241 a
//