From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Pig MHC class II (SLA-DR-alpha) mRNA, partial cds.
Date: 29 Dec 92 21:38:45 GMT
Distribution: bionet
Checksum: 35444 4

LOCUS       PIGMHCIIDC   1300 bp ss-mRNA            MAM       15-DEC-1992
DEFINITION  Pig MHC class II (SLA-DR-alpha) mRNA, partial cds.
ACCESSION   M92445
KEYWORDS    cell surface glycoprotein; class II gene;
            immunoglobulin heavy chain; integral membrane protein;
            major histocompatibility complex.
SOURCE      Sus scrofa (strain Minnesota miniature swine, sub_species
            domesticus) (library: PCDV1 (SLAc)) adult spleen and blood cDNA to
            mRNA.
  ORGANISM  Sus scrofa
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Artiodactyla; Suiformes; Suidae.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Hirsch,F., Germana,S., Gustafsson,K., Pratt,K., Sachs,D.H. and
            Leguern,C.
  TITLE     Structure and expression of class II alpha genes in miniature swine
  JOURNAL   J. Immunol. 149, 841-846 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     74..145
                     /gene="SLA-DR-alpha"
                     /codon_start=1
                     /citation=[1]
     mat_peptide     146..832
                     /product="MHC class II DR-alpha"
                     /gene="SLA-DR-alpha"
                     /codon_start=1
                     /citation=[1]
     CDS             <74..>832
                     /gene="SLA-DR-alpha"
                     /product="MHC class II DR-alpha"
                     /codon_start=1
                     /translation="ALPTLIEASKEKMTILGVPVLGFVITILNLQKSWAIVENHVIIQ
                     AEFYLSPDKSGEFMFDFDGDEIFHVDMEKRETVWRLEEFGHFASFEAQGALANIAVDK
                     ANLEILIKRSNNTPNTNVPPEVTVLSDKPVELGEPNILICFIDKFSPPVVNVTWLRNG
                     SPVTRGVSETVFLPREDHLFRKFHYLPFMPSTEDVYDCQVEHWGLDKPLLKHWEFEAQ
                     TPLPETTENTVCALGLIVALVGIIVGTVLIIKGVR"
BASE COUNT      317 a    338 c    294 g    351 t
ORIGIN      
        1 cgagttgtct tcacggaggt gaacagctgg agtatcgctg ggcttgtatt gctgtccatc
       61 ctgacccacc atagctctac cgaccctcat cgaggcatct aaggagaaaa tgaccatact
      121 tggggtccca gtcctgggat ttgtcatcac catcttgaac cttcagaaat catgggctat
      181 cgtagagaat cacgtgatca tccaggctga gttctatctg agccctgaca aatctggcga
      241 gtttatgttt gactttgacg gtgatgagat tttccacgtg gatatggaaa agagggagac
      301 ggtctggcga cttgaagaat ttggacattt tgccagcttt gaggctcagg gtgcactggc
      361 caacatagct gtggacaaag ccaacctgga aatcctgatc aagcgctcca acaacacccc
      421 gaacaccaat gtacctccag aagtgactgt gctctcagac aagcctgttg aactgggaga
      481 gcccaacatc ctcatctgtt tcatcgacaa gttctccccg ccagtggtca atgtcacctg
      541 gcttcgaaat ggctcccctg tcaccagagg agtgtcagag acagtcttcc tgccccggga
      601 ggaccacctt ttccgcaagt tccactatct ccccttcatg ccctcaaccg aggatgtcta
      661 tgactgccag gtggagcact ggggtttgga caagcctctt ctcaagcact gggagtttga
      721 agctcaaacc cccctcccag agactacaga gaacaccgtg tgtgctctgg gcctgattgt
      781 ggctctggtg ggcatcatcg tcgggaccgt cctcatcatc aagggtgtgc gcaaaggcaa
      841 cgccactgaa caccgagggc ctctgtgagg tgcttgcagg gaatggactt tgttaaagat
      901 caatgaagat atttcctctt gaacagcttt acaaacccag cgatactcca gctgttcacc
      961 tccgtgaaga caactctcct tcagcacttt ccagccctga agccactcta agtgttgatg
     1021 ccttctttaa tcttcaaatt ctaacatctg gttattccct gtttgttacc ccttcttgtg
     1081 ctggctttcc ctccatttcc acagcctttt tattatcacc atgtaatgcc tttggaagag
     1141 atcccatggg atcctttctc tgctatgaaa ccttttgaat gttctatgga ggcatctact
     1201 gtatacttat tacttggagt ttcttccaac tgtgattgtg atttttctga atacaataaa
     1261 ctttgagtgg gccttaggtg gaaaaaaaaa aaaaaaaaaa
//