From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for transketolase
Date: 10 Sep 92 10:33:03 GMT
Distribution: bionet
Checksum: 14067     6

LOCUS       HUMTRANSK    2104 bp ss-RNA             PRI       10-SEP-1992
DEFINITION  H.sapiens mRNA for transketolase
ACCESSION   X67688
KEYWORDS    transketolase.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Singleton,C.K.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 2104)
  AUTHORS   McCool,B.A., Plonk,S.G., Martin,P.R. and Singleton,C.K.
  TITLE     Cloning of human transketolase cDNA and comparison of the
            nucleotide sequence of the coding region in Wernicke-Korsakoff and
            non-Wernicke-Korsakoff individuals
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 2104)
  AUTHORS   Abedina,M.
  TITLE     Nucleotide and predicted amino acid sequence of a cDNA clone
            encoding part of Human transketolase
  JOURNAL   Biochem. Biophys. Res. Commun. 183, 1159-1166 (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=frontal cortex, liver; *source: cell_line=Hela
            (nucleotides residues 1-200 only); *source: clone_library=frontal
            cortex and liver cDNA; *source: clone=pTKa-1, pTKd-1;
            From EMBL    entry HSTRANSK;  dated 21-AUG-1992.
FEATURES             Location/Qualifiers
     CDS             69..1940
                     /EC_number="2.2.1.1"
                     /note="homodimer"
                     /product="transketolase"
                     /evidence=EXPERIMENTAL
                     /codon_start=1
                     /translation="MESYHKPDQQKLQALKDMANRLRISSIQASSAAGSGHPTSCCSA
                     AVIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRK
                     ISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSE
                     GSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDG
                     HSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYS
                     QIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDR
                     IIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAF
                     FTRAFDQIRMAAISESNINLCGSHCGVSIGEDGASQMALEDLAMFRSVPTSTVFYPSD
                     GVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGA
                     GVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEG
                     GIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA"
BASE COUNT      529 a    602 c    590 g    383 t
ORIGIN
        1 gcgctgtact cgcagcagcc actatctctg tgtgtgcgcg tgtgcgcgtg gtccccgcct
       61 gccgcaccat ggagagctac cacaagcctg accagcagaa gctgcaggcc ttgaaggata
      121 tggccaaccg cctacgtatc agctccatcc aggcctcctc tgcggcgggc tctggccacc
      181 ccacgtcatg ctgcagcgcc gcagtgatca tggctgtcct ctttttccac accatgcgct
      241 acaagtccca ggacccccgg aatccgcaca atgaccgctt tgtgctctcc aagggccatg
      301 cagctcccat cctctacgcg gtctgggctg aagctggttt cctggccgag gcggagctgc
      361 tgaacctgag gaagatcagc tccgacttgg acgggcaccc ggtcccgaaa caagctttca
      421 ccgacgtggc cactggctcc ctgggccagg gcctcggggc cgcttgtggg atggcctaca
      481 ccggcaaata cttcgacaag gccagctacc gagtctattg cttgctggga gatggggagc
      541 tgtcagaggg ctctgtatgg gaggccatgg ccttcgccag catctataag ctggacaacc
      601 ttgtggccat tctagacatc aatcgcctgg gccagagtga cccggccccg ctgcagcacc
      661 agatggacat ctaccagaag cggtgcgagg ccttcggttg gcatgccatc atcgtggatg
      721 gacacagcgt ggaggagctg tgcaaggcct ttggccaggc caagcaccag ccaacagcca
      781 tcattgccaa gaccttcaag ggccgaggga tcacgggggt agaagataag gagtcttggc
      841 atgggaagcc cctccccaaa aacatggctg agcagatcat ccaggagatc tacagccaga
      901 tccagagcaa aaagaagatc ctggcaaccc ctccacagga ggacgcaccc tcagtggaca
      961 ttgccaacat ccgcatgccc agcctgccca gctacaaagt tggggacaag atagccaccc
     1021 gcaaggccta cgggcaggca ctggccaagc tgggccatgc cagtgaccgc atcatcgccc
     1081 tggatgggga caccaaaaat tccaccttct cggagatctt caaaaaggag cacccggacc
     1141 gcttcatcga gtgctacatt gccgagcaga acatggtgag catcgcggtg ggctgtgcca
     1201 cccgcaacag gacggtgccc ttctgcagca cttttgcagc cttcttcacg cgggcctttg
     1261 accagattcg catggcggcc atctccgaga gcaacatcaa cctctgcggc tcccactgcg
     1321 gcgtttccat cggggaagac ggggcctccc agatggccct agaagatctg gctatgtttc
     1381 ggtcagtccc cacatcaact gtcttttacc caagtgatgg cgttgctaca gagaaggcag
     1441 tggaactagc cgccaataca aagggtatct gcttcatccg gaccagccgc ccagaaaatg
     1501 ccatcatcta taacaacaat gaggacttcc aggtcggaca agccaaggtg gtcctgaaga
     1561 gcaaggatga ccaggtgacc gttatcgggg ctggggtgac cctgcacgag gccttggccg
     1621 ctgccgaact gctgaagaaa gaaaagatca acatccgcgt gctggacccc ttcaccatca
     1681 agcccctgga cagaaaactc attctcgaca gcgctcgtgc caccaagggc aggatcctca
     1741 ccgtggagga ccattattat gaaggtggca ttggtgaggc tgtgtccagt gcagtagtgg
     1801 gcgagcctgg catcactgtc acccacctgg cagttaaccg ggtaccaaga agtgggaagc
     1861 cagctgagct gctgaagatg tttggtatcg acagggatgc cattgcacaa gctgtgaggg
     1921 gcctcatcac caaggcctag ggcgggtatg aagtgtgggg cgggggtcta tacattcctg
     1981 agattctggg aaaggtgctc aaagatgtac tgagaggagg ggtaaatata tgttttgaga
     2041 aaaatgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2101 aaaa
//