From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human tumor necrosis factor 6 (hyaluronate binding protein) TSG-6
Date: 29 Dec 92 20:56:43 GMT
Distribution: bionet
Checksum: 21557 4

LOCUS       HUMPMTRTSG   1342 bp ds-DNA             PRI       11-DEC-1992
DEFINITION  Human tumor necrosis factor 6 (hyaluronate binding protein) TSG-6
            gene, promoter region.
ACCESSION   L07295
KEYWORDS    hyaluronate binding protein; tumor necrosis factor.
SOURCE      Homo sapiens (library: Promega) mature foreskin DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Lee,T., Klampfer,L., Shows,T.B. and Vilcek,J.
  TITLE     Transcriptional regulation of TSG6,a TNF and IL-1 inducible primary
            response gene coding for a secreted hyaluronan binding protein
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     TATA_signal     20..27
                     /evidence="EXPERIMENTAL"
     protein_bind    105..115
                     /bound_moiety="NF-IL6"
                     /standard_name="NF-IL6: transcription factor 5 binding
                     site"
     protein_bind    118..126
                     /bound_moiety="AP-1"
                     /standard_name="AP-1 binding element"
     protein_bind    123..129
                     /bound_moiety="IRF-1"
                     /standard_name="IRF-1 (inteferon regulatory factor)
                     binding element"
     CAAT_signal     131..136
     protein_bind    623..629
                     /bound_moiety="GRE"
                     /standard_name="GRE (glucocorticoid response element)"
     protein_bind    941..947
                     /bound_moiety="IRF-1"
                     /standard_name="IRF-1 (interferon regulatory factor)
                     binding element"
     protein_bind    1010..1016
                     /bound_moiety="IRF-1"
                     /standard_name="IRF-1 (inteferon regulatory factor)
                     binding element"
     protein_bind    1142..1148
                     /bound_moiety="GRE"
                     /standard_name="GRE (glucocorticoid response element)"
     protein_bind    1282..1291
                     /bound_moiety="NF-IL6"
                     /standard_name="NF-IL6; transcription factor 5 binding
                     site"
BASE COUNT      466 a    248 c    240 g    388 t
ORIGIN      
        1 tttgtagacc aaaggtgtag aaaatttatc aaaaaaagtt gacactccag tctcatgaga
       61 ggttaccgta aaaggcgaca tctcaatgtg ttaatagagt cacagacttc gtttaggaga
      121 ctgagtaaac gtaaccgttg gttttgattc ctctatctta ctagtagata caaaatttta
      181 attgaatgat tcttgcctca agtaaataac aatcagtgtt tgtgaaaaga caatctttca
      241 aacacattga actacgtcta aatcgtcact aattttcttt tagcttgaag tcatccttaa
      301 agttctattt aggatttaca gaataaacgt cacagttaat accctatacc ccaatttgtg
      361 attagaaaat aaccattaca acctgaccga aaagatttgt aacagttcgg acacattttt
      421 taaattttgt ttttcatacg tgtcgaacct cttaggatta aaaagaggtc atatatactg
      481 aaggaataag agacggacga aaagaaggtc ccaccccaga caacgtcaga aaccacacaa
      541 taccagtcgt cgatttattt acatagtcga gggtcttttc ataaagttaa agtctcgcag
      601 tcctacaagg tcgtcgaaac cctacaggat atattgtgtc aaaagggtcc ggtgtttaag
      661 aacttcacaa ccctcttcca ccatctgatt gtttcaatta tttttgaaca gggatcgaag
      721 ggatctggtg agattgaaac ttcttctgct agttccatta tctattatta ataatgtcat
      781 ttcagtagta cagaagttta tagggtttga aaggagaagg aaacacatct taggaaccca
      841 ttgtatagac tattatgagg gtgatgcgac tacgattacc gtaaaggata acaagtaact
      901 atcggtaaat aaccgttgaa aactaaaaaa atgttttaac cagtaaaaaa cgatgaatct
      961 aagagatgaa aaccagagtt taacgaaggg taagtgagga taatatcgta agtaaagagg
     1021 gtacgaaaga atcagggagg ttactacaac ctcaagaaac tttttcggtt gaacgatctg
     1081 tacgagacca aacttcaatc gaaacttagg gaatctgtag aaacgaaact tgtagagtcc
     1141 acacaagacc agagtagaga agagttttct cgtcaatacc cctacatccg actctcatgt
     1201 cttaaataac ctacgagtga ctccatatgt atttcaatga tcgtaacttt tagaaataaa
     1261 acctgaccac cgtgtacttt ctactccctt acataggttc aagtgtctat cccaatcact
     1321 taaattcaaa caacgttttc tc
//