From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human ADP-ribosylation factor 1 gene, exons 2-5.
Date: 22 Aug 92 10:00:45 GMT
Distribution: bionet
Checksum: 16491     6

LOCUS       HUMADPRF2    2558 bp ds-DNA             PRI       22-AUG-1992
DEFINITION  Human ADP-ribosylation factor 1 gene, exons 2-5.
ACCESSION   M84332
KEYWORDS    ADP-ribosylation factor 1.
SEGMENT     2 of 2
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Lee,C.-M., Haun,R.S., Tsai,S.-C., Moss,J. and Vaughan,M.
  TITLE     Characterization of the human gene encoding ADP-ribosylation factor
            1, a guanine nucleotide-binding activator of cholera toxin
  JOURNAL   J. Biol. Chem. 267, 9028-9034 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     intron          <1..313
                     /number=1
     CDS             join(351..498,578..688,827..951,1088..1249)
                     /product="ADP-ribosylation factor 1"
                     /codon_start=1
                     /translation="MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVT
                     TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNE
                     AREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCA
                     TSGDGLYEGLDWLSNQLRNQK"
     exon            314..498
                     /number=2
     intron          499..577
                     /number=2
     exon            578..688
                     /number=3
     intron          689..826
                     /number=3
     exon            827..951
                     /number=4
     intron          952..1087
     exon            1088..2446
                     /number=5
     polyA_signal    2342..2347
     polyA_site      2359
     polyA_signal    2426..2431
     polyA_site      2445
     polyA_site      2446
BASE COUNT      523 a    731 c    717 g    587 t
ORIGIN
        1 ctggaagcca gtcctcaggc agccagcctc ccctcctgca taggctggga tgaggcagcc
       61 tttctggcca tgcagctgtg gggacagctt cccaagatga gggcaacagt ttctcaattc
      121 ctgactcagc cattttccct cagcccccat cctgaggtgg atttgggggg catgggaggc
      181 agggctcttt ccctgtttcc ctgcaggctt ccaggaggtg gggtgaggca gtggtgcatc
      241 cctgggtggg tgggttctga gcaaccactg ctgggcagca cagaaccaga catggagcac
      301 cttgtctctc caggtgtccc tggccagtgt ccttccacct gtccacaagc atggggaaca
      361 tcttcgccaa cctcttcaag ggcctttttg gcaaaaaaga aatgcgcatc ctcatggtgg
      421 gcctggatgc tgcagggaag accacgatcc tctacaagct taagctgggt gagatcgtga
      481 ccaccattcc caccataggt gaggtggggg ccagcaggga gtgggctggg ctgggctggg
      541 ccaaggtaca aggcctcacc ctgcatcccg cacccaggct tcaacgtgga aaccgtggag
      601 tacaagaaca tcagcttcac tgtgtgggac gtgggtggcc aggacaagat ccggcccctg
      661 tggcgccact acttccagaa cacacaaggt aagtggctgg ggcctggtcc catgggcact
      721 cctgcttcta gagagggggg gccagcccat agatggggca tcgatgccca tagatgcggc
      781 aggggggctg tgttcccatg accatttgac actggctgcc cggcaggcct gatcttcgtg
      841 gtggacagca atgacagaga gcgtgtgaac gaggcccgtg aggagctcat gaggatgctg
      901 gccgaggacg agctccggga tgctgtcctc ctggtgttcg ccaacaagca ggtaggcgcc
      961 cgggccagcc tggggaatgt gaggagccag tgtgggttcc gcctggtggt aggggttact
     1021 ggaggctggt ggggcccctt tctctgtcct gtggacagcc cttcccacca acccttcctt
     1081 cccccaggac ctccccaacg ccatgaatgc ggccgagatc acagacaagc tggggctgca
     1141 ctcactacgc cacaggaact ggtacattca ggccacctgc gccaccagcg gcgacgggct
     1201 ctatgaagga ctggactggc tgtccaatca gctccggaac cagaagtgaa cgcgaccccc
     1261 ctccctctca ctcctcttgc cctctgcttt actctcatgt ggcaaacgtg cggctcgtgg
     1321 tgtgagtgcc agaagctgcc tccgtggttt ggtcaccgtg tgcatcgcac cgtgctgtaa
     1381 atgtggcaga cgcagcctgc ggccaggctt tttatttaat gtaaatagtt tttgtttcca
     1441 atgaggcagt ttctggtact cctatgcaat attactcagc tttttttatt gtaaaaagaa
     1501 aaatcaactc actgttcagt gctgagaggg gatgtaggcc catgggcacc tggcctccag
     1561 gagtcgctgt gttgggagag ccggccacgc ccttggcttt agagctgtgt tgaaatccat
     1621 tttggtggtt ggtttttaac ccaaactcag tgcatttttt aaaatagtta agaatccaag
     1681 tcgagaacac ttgaacacac agaagggaga ccccgcctag catagatttg cagttacggc
     1741 ctggatgcca gtcgccagcc cagctgttcc cctcgggaac atgaggtggt ggtggcgcag
     1801 cagactgcga tcaattctgc atggtcacag tagagatccc cgcaactcgc ttgtccttgg
     1861 gtcaccctgc attccatagc catgtgcttg tccctgtgct cccacggttc ccaggggcca
     1921 ggctgggagc ccacagccac cccactatgc cgcaggccgc cctacccacc ttcaggcagc
     1981 ctatgggacg cagggcccca tctgtccctc ggtcgccgtg tggccagagt gggtccgtcg
     2041 tccccaacac tcgtgctcgc tcagacactt tggcaggatg tctggggcct caccagcagg
     2101 agcgcgtgca agccgggcag gcggtccacc tagacccaca gcccctcggg agcaccccac
     2161 ctctgtgtgt gatgtagctt tctctccctc agcctgcaag ggtccgattt gccatcgaaa
     2221 aagacaacct ctactttttt cttttgtatt ttgataaaca ctgaagctgg agctgttaaa
     2281 tttatcttgg ggaaacctca gaactggtct atttggtgtc gtggaacctc ttactgcttt
     2341 caatacacga ttagtaatca actgttttgt atacttgttt tcagttttca tttcgacaaa
     2401 caagcactgt aattatagct attagaataa aatctcttaa ctatttcacc ggctctccag
     2461 tgcttccaca caggcatgct gcccccagga gatggtgggt gcatcagcca gctttactct
     2521 aggaagtaca ggtgactgcc tagggccgcc acctcagt
//