From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus Camk-2 mRNA for Ca2+/calmodulin dependent protein kinase
Date: 30 Jul 92 10:02:05 GMT
Distribution: bionet
Checksum: 30069     7

LOCUS       MUSCAMK2     3830 bp ss-mRNA            ROD       30-JUL-1992
DEFINITION  M.musculus Camk-2 mRNA for Ca2+/calmodulin dependent protein kinase
            II beta subunit
ACCESSION   X63615
KEYWORDS    Camk-2 gene; Ser and Thr phosphorylating;
            calcium/calmodulin-dependent protein kinase II-beta; calmodulin;
            protein kinase.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Karls,U., Mueller,U., Gilbert,D.J., Copeland,N.G., Jenkins,N.A. and
            Harbers,K.
  TITLE     Structure, expression, and chromosome location of the gene for the
            beta subunit of brain-specific Ca-2+/calmodulin-dependent protein
            kinase II identified by transgene integraiton in an embryonic
            lethal mouse mutant
  JOURNAL   Mol. Cell. Biol. 12, 3644-3652 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=BALB/c; *source: tissue=brain; *source:
            clone_library=brain cDNA library; *source: chromosome=II;
            From EMBL    entry MMCAMK2;  dated 10-JAN-1992.
FEATURES             Location/Qualifiers
     CDS             26..1654
                     /product="calcium/calmodulin dependent protein kinase
                     II-beta"
                     /gene="Camk-2"
                     /codon_start=1
                     /translation="MATTVTCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKI
                     INTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDI
                     VAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGL
                     AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDED
                     QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRS
                     TVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTT
                     MGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIK
                     ESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALG
                     NLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRP
                     RTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ"
BASE COUNT      890 a   1049 c   1059 g    832 t
ORIGIN
        1 cacgccgagc ccaatcgcca ccgccatggc caccacggtg acctgcaccc gtttcaccga
       61 cgagtaccag ctatacgagg agattggcaa gggggctttc tctgtggtcc gacgctgtgt
      121 caagctctgt accggccatg agtatgcagc caagatcatt aataccaaga agctgtcggc
      181 cagagatcac cagaaactgg agagagaggc tcggatctgc cgcctgctga agcattccaa
      241 cattgtacgc ctccatgaca gcatctctga agagggcttc cactacctgg tcttcgacct
      301 ggtcactggt ggggagctct ttgaagacat cgtggcaaga gagtactaca gtgaagctga
      361 tgccagtcac tgcatccagc agatcctgga agctgttctc cattgtcacc aaatgggggt
      421 cgtccacaga gacctcaagc ctgagaacct gcttctggcc agcaaatgca aaggcgccgc
      481 agtgaagctg gcagacttcg gcctggccat cgaggttcag ggagaccagc aggcatggtt
      541 tggatttgcg ggaacgccag gctacctgtc tcccgaggtc cttcggaagg aggcctacgg
      601 caaacctgtg gacatctggg catgtggggt gatcctgtat atcctgctgg tgggctaccc
      661 acctttctgg gatgaggacc aacacaagct gtaccagcag atcaaggctg gggcgtatga
      721 tttcccatcc cctgagtggg acaccgttac tcctgaagcc aaaaacctca tcaaccagat
      781 gctgaccatc aaccctgcca agcgcatcac ggcccatgag gccctgaagc acccatgggt
      841 ctgccaacgt tccaccgtgg cctctatgat gcacagacag gagactgtgg aatgtctgaa
      901 gaagttcaat gcaaggagga agctcaaggg agccatcctc accactatgc tggccacacg
      961 gaatttctca gtgggcagac agaccaccgc tccggccaca atgtccaccg cggcctccgg
     1021 caccaccatg gggctggtgg aacaagccaa gagtttactc aacaagaaag cagatggagt
     1081 caagccccag acaaacagca ccaaaaacag ctcggccatc accagcccca aaggatctct
     1141 ccctcctgct gccctggagc ctcaaaccac cgttatccat aacccagtgg acgggattaa
     1201 ggaatcttcc gacagcacca acacaaccat agaggatgaa gatgccaaag cccggaagca
     1261 ggaaatcatc aagaccacag agcagctcat tgaggccgtc aacaatgggg actttgaggc
     1321 ctatgcgaaa atctgtgacc caggcctgac ctcatttgag cctgaagctc tgggcaacct
     1381 ggtcgaaggg atggatttcc acagattcta ctttgagaac ctgctggcca agaacagcaa
     1441 gccgatccac accaccatcc tgaacccgca cgtgcacgtc attggcgagg atgcggcatg
     1501 catcgcctac atccgcctca cacagtacat cgatggccag ggcagacccc gtaccagcca
     1561 gtccgaagag acccgtgtgt ggcaccgccg cgacggcaag tggcagaatg tacatttcca
     1621 ctgctcgggc gctccagtgg ccccgctgca gtgagagctg cgcctggttt cgccggacag
     1681 agttggtgtt tggagcccag ccgccctcgg gcgcacggcc tgcctgtcgc atgtttgtgt
     1741 ctgcctcgtc ccctcccctg gtgcctgtgt ctgcagaaaa acaagaccag atgtgatttg
     1801 tttttaaaaa taagatgatg acaacgacaa ccacacgcaa accaacaaac aaaattttgg
     1861 catcggatga aatggaaaac aagcaaacaa acaaaaacct aaagaaagga aaaagctgta
     1921 aaaatctggc atttgtgggg ccaccccacc cccaagctcc actgtgtctg ttgtgctcct
     1981 ggctttgggg accctcaggg cgtgaatgtg cccatgccga ccgtgttagt ctgtaggtac
     2041 cgcactcacc ccataccttg ggcgtctgca tcctccctcc catgcatggg ccccacgtgc
     2101 taacctggct gttgtggtgt caggtgtctt gggaagggct gggggctgcc tcctttcctg
     2161 ctagttgtgc ctgagagttg ctgctgctcc tgctttcccc tacctgtccc ttgtcccgtc
     2221 ctgtgaaggg ctgggagggt gctcctctag ccaaggacct acctttgccc catggagtgt
     2281 gtagaagctt gtccccgagg tcatcagaaa agaacctggg ctctcagccc cggttctttg
     2341 gggagtgagg tatggaggta cggatcttgc ctccagacct cctgcctggc aggggttggt
     2401 taagaaggcc tgctggctgc agtgcctacc catgtagcta tgaagagagg actgggcaga
     2461 ggatggcctc cttcctgttt ggggtacttg tcccttccct gccaccagca gctgagcaac
     2521 agtggcccac ccctggcctg ggaagttcct ctctgaagtt ggcagcagac cctaatgaag
     2581 atggagaacc tgagatactg gacggatact gggaacaggc caggctgcgt ctagggtgtt
     2641 tgtccactca gcttggagcc tgggtgttcg agacttggtt aaatgttgca gaatgtggta
     2701 aagaggggcc agaagttggg ttctagactt ctgggcaatg caggtccata caagtgtttg
     2761 atgaaatggg agtgctttct tgacctgggc ctagagaaga gcatatgcca cctagaggca
     2821 tgtggaaggc caaaattggt tagggctgta ttgtgtgggg ctcttccagg taggccagag
     2881 acacagctta gagagaaggc aggctggggg cagagatata tgctgtgggg cctggatacc
     2941 agtgggtggg tggagggccc atcaggacag tgtggcacct ccaagggccc agtggtgctc
     3001 ctaggtgccg gctgcctgga ctcgttgtgg gtggccctgg cccttggtga ctgagggaat
     3061 cattaaggct ggacatgtta caaagtcagg ctagggagat ataggtctga agccgggttg
     3121 ggtgggggtg gtcagaggct ttgactgcag aggttcatgg gcctccaccc caacgctgcc
     3181 cactttaaat tcatgtcatt ttcaaccagg attttcttta tcttttacta caaatcaagc
     3241 caagggaggg gcacgaagtg gggaacggga cacaggatcc taaactccaa ggggactgtc
     3301 cacctacaga cactcagtgg ataccacctt tcatccacac tgtgcccagg acagctgttc
     3361 cctacccatg gacacagggt aaacatctgc caggctccac ttgagtggcc caaggccatg
     3421 gaacagtggc agggcttgcc atggacagtg tgaggccctg tggcctgcca ccctggcatc
     3481 ctggggtctc ctttcctctc ccacccacct tgttatctcc acaaagctgc ctgtctggga
     3541 taatttgggg attttttttt tctgggggac aattcttttg catgaccctc taaagagcag
     3601 gacactcctg ctctaactgg ctaggtgttc gcaggtggtg gcgtcgaccg ctggccagtg
     3661 ctgtagtgtg ttactgcctg cagtactggt ggccctcctc tcttctctct ttttgctgag
     3721 ttccactgtc ttttctttct gagccttgta ggtgtacaaa acttattctt attttgttct
     3781 gtctcgggaa actgcaaata aaaaaaaaaa aaaaaaaaaa aaaggaaaaa
//