From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human tumor necrosis factor-inducible (TSG-14) mRNA, complete cds.
Date: 29 Aug 92 10:01:57 GMT
Distribution: bionet
Checksum: 44684     5

LOCUS       HUMTSG14A    1839 bp ss-mRNA            PRI       29-AUG-1992
DEFINITION  Human tumor necrosis factor-inducible (TSG-14) mRNA, complete cds.
ACCESSION   M31166
KEYWORDS    acute phase protein; pentaxin protein;
            tumor necrosis factor inducible gene.
SOURCE      Human foreskin fibroblast cell line FS-4, cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1839)
  AUTHORS   Lee,G.W.
  JOURNAL   Unpublished (1990) Dpt. of Microbiol., NYU 550 1st Ave, NY NY 10016
  STANDARD  simple staff_entry
REFERENCE   2  (sites)
  AUTHORS   Lee,T.H., Lee,G.W., Ziff,E.B. and Vilcek,J.
  TITLE     A novel secretory tumor necrosis factor-inducible protein (TSG-6)
            is a member of the family of hyaluronate binding proteins, closely
            related to the adhesion receptor CD44
  JOURNAL   J. Cell Biol. 116, 545-557 (1992)
  STANDARD  full staff_review
COMMENT
            [1]  sites; for [1].
            Draft entry and computer-readable sequence for [1] kindly submitted
            by T.H.Lee, 09-JAN-1990.
FEATURES             Location/Qualifiers
     mRNA            1..1839
                     /gene="TSG-14"
                     /partial
     CDS             74..1219
                     /note="pentaxin protein homologue"
                     /product="tumor necrosis factor"
                     /gene="TSG-14"
                     /codon_start=1
                     /translation="MHLLAILFCALWSAVLAENSDDYDLMYVNLDNEIDNGLHPTEDP
                     TPCDCGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARP
                     CAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTR
                     ADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPLRLESFSACIWVKATDV
                     LNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNS
                     EEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLT
                     GFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS"
BASE COUNT      496 a    373 c    505 g    465 t
ORIGIN
        1 gaattcgcgc tcaactcagc tcactgagag tctctcccgc cagctgtgga aagaactttg
       61 cgtctctcca gcaatgcatc tccttgcgat tctgttttgt gctctctggt ctgcagtgtt
      121 ggccgagaac tcggatgatt atgatctcat gtatgtgaat ttggacaacg aaatagacaa
      181 tggactccat cccactgagg accccacgcc gtgcgactgc ggtcaggagc actcggaatg
      241 ggacaagctc ttcatcatgc tggagaactc gcagatgaga gagcgcatgc tgctgcaagc
      301 cacggacgac gtcctgcggg gcgagctgca gaggctgcgg gaggagctgg gccggctcgc
      361 ggaaagcctg gcgaggccgt gcgcgccggg ggctcccgca gaggccaggc tgaccagtgc
      421 tctggacgag ctgctgcagg cgacccgcga cgcgggccgc aggctggcgc gtatggaggg
      481 cgcggaggcg cagcgcccag aggaggcggg gcgcgccctg gccgcggtgc tagaggagct
      541 gcggcagacg cgagccgacc tgcacgcggt gcagggctgg gctgcccgga gctggctgcc
      601 ggcaggttgt gaaacagcta ttttattccc aatgcgttcc aagaagattt ttggaagcgt
      661 gcatccagtg agacctttga ggcttgagtc ttttagtgcc tgcatttggg tcaaagccac
      721 agatgtatta aacaaaacca tcctgttttc ctatggcaca aagaggaatc catatgaaat
      781 ccagctgtat ctcagctacc aatccatagt gtttgtggtg ggtggagagg agaacaaact
      841 ggttgctgaa gccatggttt ccctgggaag gtggacccac ctgtgcggca cctggaattc
      901 agaggaaggg ctcacatcct tgtgggtaaa tggtgaactg gcggctacca ctgttgagat
      961 ggccacaggt cacattgttc ctgagggagg aatcctgcag attggccaag aaaagaatgg
     1021 ctgctgtgtg ggtggtggct ttgatgaaac attagccttc tctgggagac tcacaggctt
     1081 caatatctgg gatagtgttc ttagcaatga agagataaga gagaccggag gagcagagtc
     1141 ttgtcacatc cgggggaata ttgttgggtg gggagtcaca gagatccagc cacatggagg
     1201 agctcagtat gtttcataaa tgttgtgaaa ctccacttga agccaaagaa agaaactcac
     1261 acttaaaaca catgccagtt gggaaggtct gaaaactcag tgcataatag gaacacttga
     1321 gactaatgaa agagagagtt gagaccaatc tttatttgta ctggccaaat actgaataaa
     1381 cagttgaagg aaagacattg gaaaaagctt ttgaggataa tgttactaga ctttatgcca
     1441 tggtgctttc agtttaatgc tgtgtctctg tcagataaac tctcaaataa ttaaaaagga
     1501 ctgtattgtt gaacagaggg acaattgttt tacttttctt tggttaattt tgttttggcc
     1561 agagatgaat tttacattgg aagaataaca aaataagatt tgttgtccat tgttcattgt
     1621 tattggtatg taccttatta caaaaaaaat gatgaaaaca tatttatact acaaggtgac
     1681 ttaacaacta taaatgtagt ttatgtgtta taatcgaatg tcacgttttt gagaagatag
     1741 tcatataagt tatattgcaa aagggatttg tattaattta agactatttt tgtaaagctc
     1801 tactgtaaat aaaatatttt ataaaactaa acggaattc
//