From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human estrogen receptor-related protein (variant ER from breast
Date: 11 Sep 92 10:04:26 GMT
Distribution: bionet
Checksum: 32036     5

LOCUS       HUMERVBCB    2315 bp ss-mRNA            PRI       11-SEP-1992
DEFINITION  Human estrogen receptor-related protein (variant ER from breast
            cancer) mRNA, complete cds.
ACCESSION   M69297
KEYWORDS    LINE1 (L1) repetitive sequence; estrogen receptor-related protein.
SOURCE      Homo sapiens (library: lambda ZAP-II) breast cancer cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2315)
  AUTHORS   Dotzlaw,H., Alkhalaf,M. and Murphy,L.C.
  TITLE     Characterization of estrogen receptor variant mRNAs from human
            breast cancers
  JOURNAL   Mol. Endocrinol. 6, 773-785 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     misc_feature    1..883
                     /note="estrogen receptor-related sequence"
     CDS             241..903
                     /gene="estrogen receptor-related protein"
                     /codon_start=1
                     /translation="MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYL
                     DSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNS
                     VSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQG
                     GRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQELPT
                     LC"
     repeat_region   901..2315
                     /rpt_family="LINE I related"
     CDS             1216..1494
                     /note="ORF 2"
                     /codon_start=1
                     /translation="MGKDFMSKTPKAMATKAKIDKWDLIKLKSFCSLLGYLKTENTAK
                     ETTIRLNRQPTEWEKIFAIYSSDKGLISRIYKELKQIYKKKGTPSTSG"
     CDS             1500..1931
                     /note="ORF 3"
                     /codon_start=1
                     /translation="MNRHFSKEDIYAANRHMKKCSSSLAIREMQIKTTMRYHLTPVRM
                     VIIRKSGNDRCWRGCGEIGTLLHCWWDCKLVQPLWKTVWRFLRDLQLEIPFDPAIPLL
                     GIYPKDYKSCCYKDTCTRMFIAALFTIAKTWNQPKYPTTIG"
     polyA_signal    2302..2307
     polyA_site      2315
BASE COUNT      716 a    578 c    559 g    462 t
ORIGIN
        1 gagcccagga gctggcggag ggcgttcgtc ctgggactgc acttgctccc gtcgggtcgc
       61 ccggcttcac cggacccgca ggctcccggg gcagggccgg ggccagagct cgcgtgtcgg
      121 cgggacatgc gctgcgtcgc ctctaacctc gggctgtgct ctttttccag gtggcccgcc
      181 ggtttctgag ccttctgccc tgcggggaca cggtctgcac cctgcccgcg gccacggacc
      241 atgaccatga ccctccacac caaagcatcc gggatggccc tactgcatca gatccaaggg
      301 aacgagctgg agcccctgaa ccgtccgcag ctcaagatcc ccctggagcg gcccctgggc
      361 gaggtgtacc tggacagcag caagcccgcc gtgtacaact accccgaggg cgccgcctac
      421 gagttcaacg ccgcggccgc cgccaacgcg caggtctacg gtcagaccgg cctcccctac
      481 ggccccgggt ctgaggctgc ggcgttcggc tccaacggcc tggggggttt ccccccactc
      541 aacagcgtgt ctccgagccc gctgatgcta ctgcacccgc cgccgcagct gtcgcctttc
      601 ctgcagcccc acggccagca ggtgccctac tacctggaga acgagcccag cggctacacg
      661 gtgcgcgagg ccggcccgcc ggcattctac aggccaaatt cagataatcg acgccagggt
      721 ggcagagaaa gattggccag taccaatgac aagggaagta tggctatgga atctgccaag
      781 gagactcgct actgtgcagt gtgcaatgac tatgcttcag gctaccatta tggagtctgg
      841 tcctgtgagg gctgcaaggc cttcttcaag agaagtattc aagaacttcc aacactatgt
      901 tgaataggat ggtactggta ccaaaacaga gatatagacc aatggaacag aacagagccc
      961 tcagaaataa taccacacat ctacaaccat ctgatctttg acaaacgtga caaaaacaag
     1021 aaatggggaa aggattccct atttaataaa tagtgctggg aaaactggct agccatatgt
     1081 agaaagctga aactggatca cttccttaca ccttatacaa aaattaattc aagatggatt
     1141 aaagacttaa atgttagaac taaaaccata aaaaccctag aagaaaacct aggcaatacc
     1201 attcaggaca taggcatggg caaggacttc atgtctaaaa caccaaaagc aatggcaaca
     1261 aaagccaaaa ttgacaaatg ggatctaatt aaactaaaga gcttctgttc tttgctgggg
     1321 tatctgaaga ctgaaaacac agcaaaagaa actaccatca gactgaacag gcaacctaca
     1381 gaatgggaga aaatttttgc aatctactca tctgacaaag ggctaatatc cagaatctac
     1441 aaagaactca aacaaattta caagaaaaaa ggaaccccat caacaagtgg gtgaaggata
     1501 tgaacagaca cttctcaaaa gaagacattt atgcagccaa cagacacatg aaaaaatgct
     1561 catcatcatt ggccatcaga gaaatgcaaa tcaaaaccac aatgagatac catctcacac
     1621 cagttagaat ggtgatcatt agaaagtcag gaaacgacag gtgctggaga ggatgtggag
     1681 aaataggaac acttttacac tgttggtggg actgtaaact ggttcaacca ttgtggaaga
     1741 cagtgtggcg attcctcagg gatctacaac tagaaatacc atttgaccca gccatcccat
     1801 tactgggtat atacccaaag gattataaat catgctgcta taaagacaca tgcacacgta
     1861 tgtttattgc ggcactattc acaatagcaa agacttggaa ccaacctaaa tatccaacaa
     1921 caataggcta gattaagaaa atgtggcaca tatacaccat ggaatactat gcagccataa
     1981 aaaaggatga gttcatatac ttgtagggac atggatgaag ctggaaacca tcattctcag
     2041 caaactattg caaggacaaa aaaccaaaca tgcatgttct cactcatagg tgggaattga
     2101 acaataagaa cacttggaca cagggtgggg aacattacac actggggcct gttgtggggt
     2161 ggggggaggg gggagggata gcattaggag atataactaa tgtaaatgat gagttaatgg
     2221 gtgcagcaca ccaacatggc acatgtatac atatgtaaca aacctgcaca ttgtgcacat
     2281 gtaccctaga acttaaagta taataaaaaa tattt
//