From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus NT-3 gene for neurotrophin-3
Date: 3 Jan 93 22:07:53 GMT
Distribution: bionet
Checksum: 36402 4

LOCUS       MUSNT3       1284 bp ds-DNA             ROD       21-DEC-1992
DEFINITION  M.musculus NT-3 gene for neurotrophin-3
ACCESSION   X53257
KEYWORDS    NT-3 gene; brain-derived neurotrophic factor; nerve growth factor;
            neurotrophin-3.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Hohn,A., Leibrock,J., Bailey,K. and Barde,Y.A.
  TITLE     Identification and characterization of a novel member of the nerve
            growth factor/brain-derived neurotrophic factor family
  JOURNAL   Nature 344, 339-341 (1990)
  STANDARD  full automatic
COMMENT     *source: tissue_library=EMBL3 genominc DNA library; *source:
            sub_clone=HindIII and PstI fragments in Bluescript SK+;
               From EMBL    entry MMNT3;  dated 30-NOV-1992.
FEATURES             Location/Qualifiers
     sig_peptide     181..597
                     /gene="NT-3"
     misc_feature    571..579
                     /note="N-glycosylation site"
     mat_peptide     598..954
                     /product="neurotrophin-3"
                     /gene="NT-3"
     misc_feature    793..810
                     /note="PCR primer"
     misc_feature    892..909
                     /note="PCR primer"
     CDS             181..957
                     /gene="NT-3"
                     /product="neurotrophin-3"
                     /codon_start=1
                     /translation="MSILFYVIFLAYLRGIQGNSMDQRSLPEDSLNSLIIKLIQADIL
                     KNKLSKQMVDVKENYQSTLPKAEAPREPEQGEATRSEFQPMIATDTELLRQQRRYNSP
                     RVLLSDSTPLEPPPLYLMEDYVGNPVVANRTSPRRKRYAEHKSHRGEYSVCDSESLWV
                     TDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQC
                     KTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT"
BASE COUNT      358 a    298 c    293 g    335 t
ORIGIN      
        1 ggaaaccccg cccgctataa ataacaggga ggagtttacc tcatttgtta gactggtggt
       61 accctctcct cactctcaga ttgtcagcct cggtggctga tgccagaatg acaggggctc
      121 ttccggccag ctgttaacac ctgtgtttcc ttttttcaga tcttacaggt gaacaaggtg
      181 atgtccatct tgttttatgt gatatttctt gcttatctcc gtggcatcca aggcaacagc
      241 atggatcaaa ggagtttgcc ggaagactct ctcaattccc tcatcatcaa gctgatccag
      301 gcggatatct tgaaaaacaa gctttccaaa cagatggtgg atgttaagga aaattaccag
      361 agcaccctgc ccaaagcaga ggcacccagg gaaccagagc agggagaggc caccaggtca
      421 gagttccagc caatgattgc aacggacaca gagctactac ggcaacagag acgctacaat
      481 tcgccccggg tcctgctgag tgacagcacc cctttggagc cccctccctt atacctaatg
      541 gaggattatg tgggcaaccc ggtggtagcc aatagaacct caccacggag gaaacgctat
      601 gcagaacata agagtcaccg aggagagtac tcagtgtgtg acagtgagag cctgtgggtg
      661 accgacaagt cctcagccat tgacattcgg ggacaccagg tcacagtgct gggggagatc
      721 aaaaccggta actctcctgt gaaacaatat ttttatgaaa cgagatgtaa agaagccagg
      781 ccggtcaaaa acggttgcag ggggattgat gacaaacact ggaactctca gtgcaaaact
      841 tcgcaaacct atgtccgagc actgacttca gaaaacaaca aactcgtagg ctggcgctgg
      901 atacgaatag acacttcctg tgtgtgtgcc ttgtcgagaa aaattggaag aacatgaatt
      961 ggcatctgtc cccacatata aattattact ttaaattata tgatatgcat gtagcatata
     1021 aatgtttata ttgtttttat atattataag ttgaccttta tttattaaac ttcagcaacc
     1081 cttacagtat ataagctttt ttctcaataa aattcgtgtg cttgcctccc ctcaggcctt
     1141 tcccatctgt taaccttgtt ttgtgattgg gctctcggga acccttctgt aaaacctgtg
     1201 tacaccagta tttggcattc agtattgtca aggccatgac tgtggtttca gtaaactttc
     1261 ttaaaatcgg atgagtcaga gttg
//