From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human neurotrophin-4 (NT-4) gene, complete cds.
Date: 7 Apr 92 10:05:43 GMT
Distribution: bionet
Checksum: 05239     4

LOCUS       HUMPPNT4P    1404 bp ds-DNA             PRI       07-APR-1992
DEFINITION  Human neurotrophin-4 (NT-4) gene, complete cds.
ACCESSION   M86528
KEYWORDS    nerve growth factor; neurotrophin-4 protein.
SOURCE      Homo sapiens placenta DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Ip,N.Y., Ibanez,C.F., Nye,S.H., McClain,J., Jones,P.F., Gies,D.R.,
            Belluscio,L., Le Beau,M.M., Espinosa,R., Squinto,S.P., Persson,H.
            and Yancopoulos,G.D.
  TITLE     Mammalian neurotrophin-4: Structure, chromosomal localization,
            tissue distribution, and receptor specificity
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 3060-3064 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             475..1107
                     /product="pre-pro neurotrophin-4 protein"
                     /gene="NT-4"
                     /codon_start=1
                     /translation="MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSP
                     RVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSG
                     WVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRG
                     VDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA"
     mat_peptide     715..1104
                     /function="nerve growth factor-related neurotrophic
                     factor"
                     /product="neurotrophin-4"
                     /gene="NT-4"
                     /codon_start=1
BASE COUNT      273 a    405 c    386 g    340 t
ORIGIN
        1 cttgtcaccc aggtggcagg ggagtggtgc actctctgct cactgcaacc tcggcctcct
       61 gggttcgagt gattctccta cctcagccta ctgagtagct gggattacag gcgtgcagca
      121 ctatgcccgg ttaattttgg tatttttggt agagatgagg tttcaccatg ttgaccagct
      181 gctctggaac tcctgacctc aagtcatcca cctgcctcag cctcccagag tgctgggatt
      241 agaggtgtgg ggcacagtgc ctggcctgta gtagttgaat atttattatt aatctacaag
      301 ttgcgcatta cgcaagccct agatataggg tcccccaaac ttctagaaca agggcttccc
      361 cacaatcctg gcaggcaagc ctcccctggg gttcccaact tctttcccca ctgaagtttt
      421 tacccccttc tctaatccca gcctccctct ttctgtctcc aggtgctccg agagatgctc
      481 cctctcccct catgctccct ccccatcctc ctccttttcc tcctccccag tgtgccaatt
      541 gagtcccaac ccccaccctc aacattgccc ccttttctgg cccctgagtg ggaccttctc
      601 tccccccgag tagtcctgtc taggggtgcc cctgctgggc cccctctgct cttcctgctg
      661 gaggctgggg cctttcggga gtcagcaggt gccccggcca accgcagccg gcgtggggtg
      721 agcgaaactg caccagcgag tcgtcggggt gagctggctg tgtgcgatgc agtcagtggc
      781 tgggtgacag accgccggac cgctgtggac ttgcgtgggc gcgaggtgga ggtgttgggc
      841 gaggtgcctg cagctggcgg cagtcccctc cgccagtact tctttgaaac ccgctgcaag
      901 gctgataacg ctgaggaagg tggcccgggg gcaggtggag ggggctgccg gggagtggac
      961 aggaggcact gggtatctga gtgcaaggcc aagcagtcct atgtgcgggc attgaccgct
     1021 gatgcccagg gccgtgtggg ctggcgatgg attcgaattg acactgcctg cgtctgcaca
     1081 ctcctcagcc ggactggccg ggcctgagac ccatgcccag gaaaataaca gagctggatg
     1141 ctgagagacc tcagggatgg cccagctgat ctaaggaccc cagtttggga actcatcaaa
     1201 taatcacaaa atcacaattc tctgattttg agctcaatct ctgcaggatg ggtgaaacca
     1261 catggggttt tggaggttga ataggagttc tcctggagca acttgagggt aataatgatg
     1321 atgatataat aataatagcc actatttact gagtgtttac tgtttcttat ccctaataca
     1381 taactcctca gatcaactct catg
//