From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human DNA for endothelin-A receptor, 5' flanking region and exon 1.
Date: 29 Dec 92 20:55:40 GMT
Distribution: bionet
Checksum: 28504 4

LOCUS       HUMETAR1     1309 bp ds-DNA             PRI       11-DEC-1992
DEFINITION  Human DNA for endothelin-A receptor, 5' flanking region and exon 1.
ACCESSION   D11144
KEYWORDS    ET-A receptor; ET-AR; endothelin-A receptor.
SEGMENT     1 of 8
SOURCE      Homo sapiens (library: lambda EMBL3 and lambda EMBL3SP6/T7) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1309)
  AUTHORS   Hosoda,K., Nakao,K., Tamura,N., Arai,H., Ogawa,Y., Suga,S.-.,
            Nakanishi,S. and Imura,H.
  TITLE     Organization, structure, chromosomal assignment, and expression of
            the gene encoding the human endothelin-A receptor
  JOURNAL   J. Biol. Chem. 267, 18797-18804 (1992)
  STANDARD  full automatic
COMMENT     Submitted (18-May-1992) to DDBJ by: Kiminori Hosoda Second Division
            Department of Medicine Kyoto University School of Medicine 54
            Shogoin, Kawahara-cho Sakyo-ku Kyoto 606 Japan Phone:  075-751-3170
            Fax:    075-771-9452.
FEATURES             Location/Qualifiers
     misc_signal     41..46
                     /note="inverted APRRE(acute phase reactant regulatory
                     element"
     misc_signal     71..76
                     /note="GATA motif"
     misc_signal     141..146
                     /note="GATA motif"
     protein_bind    198..205
                     /bound_moiety="MyoD-E2A"
                     /note="inverted binding site"
     misc_signal     318..327
                     /note="CArG box"
     misc_signal     343..348
                     /note="GATA motif"
     misc_signal     510..515
                     /note="GATA motif"
     protein_bind    832..837
                     /bound_moiety="SP-1"
     exon            859..1289
                     /number=1
     intron          1290..>1309
                     /number=1
BASE COUNT      272 a    383 c    358 g    296 t
ORIGIN      Chromosome 4.
        1 ggatcctcca gcccctgcta catggagcaa aaacgagctg tcccagacag gctctgccca
       61 aactgcagac tgataagcag agtaaatgag tgttgttatt ttaagccact acgttttata
      121 gtaatttgtt tagctgcagc agatagccgg aacagcatgg gatataacat gaccagtgct
      181 ccaacctcac acttctacca tgtgctgact ctagcagtgc actgaaggac tccaaggcag
      241 gccttccctg aggagacccc agtttttact cacatgtcac aggcagtggc ctttgtccct
      301 catctcctct cccaccccca atttaggata aagtatctgc cgtgataaag acgttgagac
      361 ccactttctg taaggtcggc ttcttcattg tttgaatttc ttgaggtttc acggagccac
      421 gcgctggaac cttccatagt ctctcctgag gctccttctt tgccctgggc tggaggtctg
      481 tagccgtggg atgctggcta caagggacaa gatagaagca aaccacctga tccagtaaac
      541 tgctgtccac ttcggctcct caacggcctc taagcttaag agggagcacg caagccaagc
      601 aaaggcggca gggaagacgg agaagaaacc acccgtgggc cctggctctg tgtccagttg
      661 ttccgtcaca gatcaaatct gcctgcacta agaggatggg ttcctctgca aggcctttcg
      721 gaattctgag tcttgtctgt caaactctac cctctctcct ccacatcccc caccttttct
      781 ttcaggaagg aaatagttaa aaaagactcc tgcccttcag ggcctggaag ggggcggcag
      841 ctttgtgctt tttagtggcc gcgtcccagg atagctggaa ggttaggacg ctcttgcggt
      901 cccagagtgg agtggaaggt ctggagcttt gggaggagac ggggaggaca gactggaggc
      961 gtgttcctcc ggagttttct ttttcgtgcg agccctcgcg cgcgcgtaca gtcatcccgc
     1021 tggtctgacg attgtggaga ggcggtggag aggcttcatc catcccaccc ggtcgtcgcc
     1081 ggggattggg gtcccagcga cacctccccg ggagaagcag tgcccaggaa gttttctgaa
     1141 gccggggaag ctgtgcagcc gaagccgccg ccgcgccgga gcccgggaca ccggccaccc
     1201 tccgcgccac ccaccctcgc tttctccggc ttcctctggc ccaggcgccg cgcggacccg
     1261 gcagctgtct gcgcacgccg agctccacgg tcggtgcaag tctttctta
//