From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Haemophilus influenzae adhesin (hmw1) gene, complete cds.
Date: 10 Apr 92 10:05:19 GMT
Distribution: bionet
Checksum: 19486    10

LOCUS       HEAHMW1AD    5116 bp ds-DNA             BCT       10-APR-1992
DEFINITION  Haemophilus influenzae adhesin (hmw1) gene, complete cds.
ACCESSION   M84616
KEYWORDS    adhesin; hmw1 gene; surface-associated protein.
SOURCE      Haemophilus influenzae (strain 12) (library: lamda EMBL3) DNA.
  ORGANISM  Haemophilus influenzae
            Prokaryota; Bacteria; Gracilicutes; Scotobacteria;
            Facultatively anaerobic rods; Pasteurellaceae.
REFERENCE   1  (bases 1 to 5116)
  AUTHORS   Leininger,E. and Barenkamp,S.J.
  TITLE     Cloning, expression, and DNA sequence analysis of genes encoding
            nontypable Haemophilus influenzae high molecular weight surface
            exposed proteins related to filamentous hemagglutinin of Bordetella
            pertussis
  JOURNAL   Infect. Immun. 60, 1303-1312 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     repeat_region   129..240
                     /rpt_type=direct tandem repeats
                     /gene="hmw1"
     CDS             351..4961
                     /product="adhesin"
                     /gene="hmw1"
                     /codon_start=1
                     /translation="MNKIYRLKFSKRLNALVAVSELARGCDHSTEKGSEKPARMKVRH
                     LALKPLSAMLLSLGVTSIPQSVLASGLQGMDVVHGTATMQVDGNKTIIRNSVDAIINW
                     KQFNIDQNEMVQFLQENNNSAVFNRVTSNQISQLKGILDSNGQVFLINPNGITIGKDA
                     IINTNGFTASTLDISNENIKARNFTFEQTKDKALAEIVNHGLITVGKDGSVNLIGGKV
                     KNEGVISVNGGSISLLAGQKITISDIINPTITYSIAAPENEAVNLGDIFAKGGNINVR
                     AATIRNQGKLSADSVSKDKSGNIVLSAKEGEAEIGGVISAQNQQAKGGKLMITGDKVT
                     LKTGAVIDLSGKEGGETYLGGDERGEGKNGIQLAKKTSLEKGSTINVSGKEKGGRAIV
                     WGDIALIDGNINAQGSGDIAKTGGFVETSGHDLFIKDNAIVDAKEWLLDPDNVSINAE
                     TAGRSNTSEDDEYTGSGNSASTPKRNKEKTTLTNTTLESILKKGTFVNITANQRIYVN
                     SSINLSNGSLTLWSEGRSGGGVEINNDITTGDDTRGANLTIYSGGWVDVHKNISLGAQ
                     GNINITAKQDIAFEKGSNQVITGQGTITSGNQKGFRFNNVSLNGTGSGLQFTTKRTNK
                     YAITNKFEGTLNISGKVNISMVLPKNESGYDKFKGRTYWNLTSLNVSESGEFNLTIDS
                     RGSDSAGTLTQPYNLNGISFNKDTTFNVERNARVNFDIKAPIGINKYSSLNYASFNGN
                     ISVSGGGSVDFTLLASSSNVQTPGVVINSKYFNVSTGSSLRFKTSGSTKTGFSIEKDL
                     TLNATGGNITLLQVEGTDGMIGKGIVAKKNITFEGGNITFGSRKAVTEIEGNVTINNN
                     ANVTLIGSDFDNHQKPLTIKKDVIINSGNLTAGGNIVNIAGNLTVESNANFKAITNFT
                     FNVGGLFDNKGNSNISIAKGGARFKDIDNSKNLSITTNSSSTYRTIISGNITNKNGDL
                     NITNEGSDTEMQIGGDVSQKEGNLTISSDKINITKQITIKAGVDGENSDSDATNNANL
                     TIKTKELKLTQDLNISGFNKAEITAKDGSDLTIGNTNSADGTNAKKVTFNQVKDSKIS
                     ADGHKVTLHSKVETSGSNNNTEDSSDNNAGLTIDAKNVTVNNNITSHKAVSISATSGE
                     ITTKTGTTINATTGNVEITAQTGSILGGIESSSGSVTLTATEGALAVSNISGNTVTVT
                     ANSGALTTLAGSTIKGTESVTTSSQSGDIGGTISGGTVEVKATESLTTQSNSKIKATT
                     GEANVTSATGTIGGTISGNTVNVTANAGDLTVGNGAEINATEGAATLTTSSGKLTTEA
                     SSHITSAKGQVNLSAQDGSVAGSINAANVTLNTTGTLTTVKGSNINATSGTLVINAKD
                     AELNGAALGNHTVVNATNANGSGSVIATTSSRVNITGDLITINGLNIISKNGINTVLL
                     KGVKIDVKYIQPGIASVDEVIEAKRILEKVKDLSDEEREALAKLGVSAVRFIEPNNTI
                     TVDTQNEFATRPLSRIVISEGRACFSNSDGATVCVNIADNGR"
BASE COUNT     1768 a   1007 c   1036 g   1305 t
ORIGIN
        1 acagcgttct cttaatacta gtacaaaccc acaataaaat atgacaaaca acaattacaa
       61 cacctttttt gcagtctata tgcaaatatt ttaaaaaata gtataaatcc gccatataaa
      121 atggtataat ctttcatctt tcatctttca tctttcatct ttcatctttc atctttcatc
      181 tttcatcttt catctttcat ctttcatctt tcatctttca tctttcatct ttcatctttc
      241 acatgaaatg atgaaccgag ggaagggagg gaggggcaag aatgaagagg gagctgaacg
      301 aacgcaaatg ataaagtaat ttaattgttc aactaacctt aggagaaaat atgaacaaga
      361 tatatcgtct caaattcagc aaacgcctga atgctttggt tgctgtgtct gaattggcac
      421 ggggttgtga ccattccaca gaaaaaggca gcgaaaaacc tgctcgcatg aaagtgcgtc
      481 acttagcgtt aaagccactt tccgctatgt tactatcttt aggtgtaaca tctattccac
      541 aatctgtttt agcaagcggc ttacaaggaa tggatgtagt acacggcaca gccactatgc
      601 aagtagatgg taataaaacc attatccgca acagtgttga cgctatcatt aattggaaac
      661 aatttaacat cgaccaaaat gaaatggtgc agtttttaca agaaaacaac aactccgccg
      721 tattcaaccg tgttacatct aaccaaatct cccaattaaa agggatttta gattctaacg
      781 gacaagtctt tttaatcaac ccaaatggta tcacaatagg taaagacgca attattaaca
      841 ctaatggctt tacggcttct acgctagaca tttctaacga aaacatcaag gcgcgtaatt
      901 tcaccttcga gcaaaccaaa gataaagcgc tcgctgaaat tgtgaatcac ggtttaatta
      961 ctgtcggtaa agacggcagt gtaaatctta ttggtggcaa agtgaaaaac gagggtgtga
     1021 ttagcgtaaa tggtggcagc atttctttac tcgcagggca aaaaatcacc atcagcgata
     1081 taataaaccc aaccattact tacagcattg ccgcgcctga aaatgaagcg gtcaatctgg
     1141 gcgatatttt tgccaaaggc ggtaacatta atgtccgtgc tgccactatt cgaaaccaag
     1201 gtaaactttc tgctgattct gtaagcaaag ataaaagcgg caatattgtt ctttccgcca
     1261 aagagggtga agcggaaatt ggcggtgtaa tttccgctca aaatcagcaa gctaaaggcg
     1321 gcaagctgat gattacaggc gataaagtca cattaaaaac aggtgcagtt atcgaccttt
     1381 caggtaaaga agggggagaa acttaccttg gcggtgacga gcgcggcgaa ggtaaaaacg
     1441 gcattcaatt agcaaagaaa acctctttag aaaaaggctc aaccatcaat gtatcaggca
     1501 aagaaaaagg cggacgcgct attgtgtggg gcgatattgc gttaattgac ggcaatatta
     1561 acgctcaagg tagtggtgat atcgctaaaa ccggtggttt tgtggagacg tcggggcatg
     1621 atttattcat caaagacaat gcaattgttg acgccaaaga gtggttgtta gacccggata
     1681 atgtatctat taatgcagaa acagcaggac gcagcaatac ttcagaagac gatgaataca
     1741 cgggatccgg gaatagtgcc agcaccccaa aacgaaacaa agaaaagaca acattaacaa
     1801 acacaactct tgagagtata ctaaaaaaag gtacctttgt taacatcact gctaatcaac
     1861 gcatctatgt caatagctcc attaatttat ccaatggcag cttaactctt tggagtgagg
     1921 gtcggagcgg tggcggcgtt gagattaaca acgatattac caccggtgat gataccagag
     1981 gtgcaaactt aacaatttac tcaggcggct gggttgatgt tcataaaaat atctcactcg
     2041 gggcgcaagg taacataaac attacagcta aacaagatat cgcctttgag aaaggaagca
     2101 accaagtcat tacaggtcaa gggactatta cctcaggcaa tcaaaaaggt tttagattta
     2161 ataatgtctc tctaaacggc actggcagcg gactgcaatt caccactaaa agaaccaata
     2221 aatacgctat cacaaataaa tttgaaggga ctttaaatat ttcagggaaa gtgaacatct
     2281 caatggtttt acctaaaaat gaaagtggat atgataaatt caaaggacgc acttactgga
     2341 atttaacctc cttaaatgtt tccgagagtg gcgagtttaa cctcactatt gactccagag
     2401 gaagcgatag tgcaggcaca cttacccagc cttataattt aaacggtata tcattcaaca
     2461 aagacactac ctttaatgtt gaacgaaatg caagagtcaa ctttgacatc aaggcaccaa
     2521 tagggataaa taagtattct agtttgaatt acgcatcatt taatggaaac atttcagttt
     2581 cgggaggggg gagtgttgat ttcacacttc tcgcctcatc ctctaacgtc caaacccccg
     2641 gtgtagttat aaattctaaa tactttaatg tttcaacagg gtcaagttta agatttaaaa
     2701 cttcaggctc aacaaaaact ggcttctcaa tagagaaaga tttaacttta aatgccaccg
     2761 gaggcaacat aacacttttg caagttgaag gcaccgatgg aatgattggt aaaggcattg
     2821 tagccaaaaa aaacataacc tttgaaggag gtaacatcac ctttggctcc aggaaagccg
     2881 taacagaaat cgaaggcaat gttactatca ataacaacgc taacgtcact cttatcggtt
     2941 cggattttga caaccatcaa aaacctttaa ctattaaaaa agatgtcatc attaatagcg
     3001 gcaaccttac cgctggaggc aatattgtca atatagccgg aaatcttacc gttgaaagta
     3061 acgctaattt caaagctatc acaaatttca cttttaatgt aggcggcttg tttgacaaca
     3121 aaggcaattc aaatatttcc attgccaaag gaggggctcg ctttaaagac attgataatt
     3181 ccaagaattt aagcatcacc accaactcca gctccactta ccgcactatt ataagcggca
     3241 atataaccaa taaaaacggt gatttaaata ttacgaacga aggtagtgat actgaaatgc
     3301 aaattggcgg cgatgtctcg caaaaagaag gtaatctcac gatttcttct gacaaaatca
     3361 atattaccaa acagataaca atcaaggcag gtgttgatgg ggagaattcc gattcagacg
     3421 cgacaaacaa tgccaatcta accattaaaa ccaaagaatt gaaattaacg caagacctaa
     3481 atatttcagg tttcaataaa gcagagatta cagctaaaga tggtagtgat ttaactattg
     3541 gtaacaccaa tagtgctgat ggtactaatg ccaaaaaagt aacctttaac caggttaaag
     3601 attcaaaaat ctctgctgac ggtcacaagg tgacactaca cagcaaagtg gaaacatccg
     3661 gtagtaataa caacactgaa gatagcagtg acaataatgc cggcttaact atcgatgcaa
     3721 aaaatgtaac agtaaacaac aatattactt ctcacaaagc agtgagcatc tctgcgacaa
     3781 gtggagaaat taccactaaa acaggtacaa ccattaacgc aaccactggt aacgtggaga
     3841 taaccgctca aacaggtagt atcctaggtg gaattgagtc cagctctggc tctgtaacac
     3901 ttactgcaac cgagggcgct cttgctgtaa gcaatatttc gggcaacacc gttactgtta
     3961 ctgcaaatag cggtgcatta accactttgg caggctctac aattaaagga accgagagtg
     4021 taaccacttc aagtcaatca ggcgatatcg gcggtacgat ttctggtggc acagtagagg
     4081 ttaaagcaac cgaaagttta accactcaat ccaattcaaa aattaaagca acaacaggcg
     4141 aggctaacgt aacaagtgca acaggtacaa ttggtggtac gatttccggt aatacggtaa
     4201 atgttacggc aaacgctggc gatttaacag ttgggaatgg cgcagaaatt aatgcgacag
     4261 aaggagctgc aaccttaact acatcatcgg gcaaattaac taccgaagct agttcacaca
     4321 ttacttcagc caagggtcag gtaaatcttt cagctcagga tggtagcgtt gcaggaagta
     4381 ttaatgccgc caatgtgaca ctaaatacta caggcacttt aactaccgtg aagggttcaa
     4441 acattaatgc aaccagcggt accttggtta ttaacgcaaa agacgctgag ctaaatggcg
     4501 cagcattggg taaccacaca gtggtaaatg caaccaacgc aaatggctcc ggcagcgtaa
     4561 tcgcgacaac ctcaagcaga gtgaacatca ctggggattt aatcacaata aatggattaa
     4621 atatcatttc aaaaaacggt ataaacaccg tactgttaaa aggcgttaaa attgatgtga
     4681 aatacattca accgggtata gcaagcgtag atgaagtaat tgaagcgaaa cgcatccttg
     4741 agaaggtaaa agatttatct gatgaagaaa gagaagcgtt agctaaactt ggcgtaagtg
     4801 ctgtacgttt tattgagcca aataatacaa ttacagtcga tacacaaaat gaatttgcaa
     4861 ccagaccatt aagtcgaata gtgatttctg aaggcagggc gtgtttctca aacagtgatg
     4921 gcgcgacggt gtgcgttaat atcgctgata acgggcggta gcggtcagta attgacaagg
     4981 tagatttcat cctgcaatga agtcatttta ttttcgtatt atttactgtg tgggttaaag
     5041 ttcagtacgg gctttaccca tcttgtaaaa aattacggag aatacaataa agtattttta
     5101 acaggttatt attatg
//