From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat peptidylglycine alpha-amidating monooxygenase (PAM) gene, exon
Date: 28 Dec 92 21:45:15 GMT
Distribution: bionet
Checksum: 64063 21

LOCUS       RATPAM26      979 bp ds-DNA             ROD       01-DEC-1992
DEFINITION  Rat peptidylglycine alpha-amidating monooxygenase (PAM) gene, exon
            27.
ACCESSION   L01693
KEYWORDS    alternative splicing;
            peptidylglycine alpha-amidating monooxygenase.
SEGMENT     26 of 26
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda Fix)
            male adult liver DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (sites)
  AUTHORS   Stoffers,D.A., Ouafik,L. and Eipper,B.A.
  TITLE     Characterization of novel mRNAs encoding enzymes involved in
            peptide alpha-amidation
  JOURNAL   J. Biol. Chem. 266, 1701-1707 (1991)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Eipper,B.A., Green,C.B., Campbell,T.A., Stoffers,D.A.,
            Keutmann,H.T., Mains,R.E. and Ouafik,L.
  TITLE     Alternative splicing and endoproteolytic processing generate
            tissue-specific forms of peptidylglycine alpha-amidating
            monooxygenase (PAM)
  JOURNAL   J. Biol. Chem. 267, 4008-4015 (1992)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 979)
  AUTHORS   Ouafik,L., Stoffers,D.A., Campbell,T.A., Johnson,R.C.,
            Bloomquist,B.T., Mains,R.E. and Eipper,B.A.
  TITLE     The multifunctional peptidylglycine alpha-amidating monooxygenase
            gene: Exon/intron organization of catalytic, processing and routing
            domains
  JOURNAL   Mol. Endocrinol. 6, 1571-1584 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            61..898
                     /number=27
                     /gene="PAM"
     polyA_signal    882..887
                     /gene="PAM"
     polyA_site      905
     intron          order(L01692:273..312,1..60)
                     /number=26
                     /gene="PAM"
                     /note=".8 kb gap"
     mRNA            join(L01668:114..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01682:51..365,L01683:65..194,
                     L01684:183..299,L01685:140..212,L01686:52..262,
                     L01687:53..253,L01688:89..204,L01689:60..159,
                     L01690:11..64,L01691:160..363,L01692:219..272,61..898)
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /partial
                     /note="alternatively spliced PAM1 mRNA"
     mat_peptide     join(L01669:24..143,L01670:71..128,L01671:187..274,
                     L01672:89..174,L01673:162..245,L01674:77..125,
                     L01675:163..230,L01676:227..307,L01677:67..143,
                     L01678:186..289,L01680:308..492,L01681:253..324,
                     L01682:51..365,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01691:160..363,L01692:219..272,61..236)
                     /EC_number="1.14.17.3"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /codon_start=1
                     /note="alternatively spliced PAM1 protein"
     mat_peptide     join(L01669:24..143,L01670:71..128,L01671:187..274,
                     L01672:89..174,L01673:162..245,L01674:77..125,
                     L01675:163..230,L01676:227..307,L01677:67..143,
                     L01678:186..289,L01680:308..492,L01681:253..324,
                     L01683:65..194,L01684:183..299,L01685:140..212,
                     L01686:52..262,L01687:53..253,L01688:89..204,
                     L01689:60..159,L01690:11..64,L01691:160..363,
                     L01692:219..272,61..236)
                     /EC_number="1.14.17.3"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /codon_start=1
                     /note="alternatively spliced PAM2 protein"
     mRNA            join(L01668:114..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01691:160..363,L01692:219..272,61..898)
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /partial
                     /note="alternatively spliced PAM2 mRNA"
     mRNA            join(L01668:114..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01692:219..272,61..898)
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /partial
                     /note="alternatively spliced PAM3a mRNA"
     mRNA            join(L01668:114..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01691:160..363,61..898)
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /partial
                     /note="alternatively spliced PAM3b mRNA"
     mRNA            join(L01668:114..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,61..898)
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /partial
                     /note="alternatively spliced PAM3 mRNA"
     mat_peptide     join(L01669:24..143,L01670:71..128,L01671:187..274,
                     L01672:89..174,L01673:162..245,L01674:77..125,
                     L01675:163..230,L01676:227..307,L01677:67..143,
                     L01678:186..289,L01680:308..492,L01681:253..324,
                     L01683:65..194,L01684:183..299,L01685:140..212,
                     L01686:52..262,L01687:53..253,L01688:89..204,
                     L01689:60..159,L01690:11..64,L01692:219..272,61..236)
                     /EC_number="1.14.17.3"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /codon_start=1
                     /note="alternatively spliced PAM3a protein"
     mat_peptide     join(L01669:24..143,L01670:71..128,L01671:187..274,
                     L01672:89..174,L01673:162..245,L01674:77..125,
                     L01675:163..230,L01676:227..307,L01677:67..143,
                     L01678:186..289,L01680:308..492,L01681:253..324,
                     L01683:65..194,L01684:183..299,L01685:140..212,
                     L01686:52..262,L01687:53..253,L01688:89..204,
                     L01689:60..159,L01690:11..64,L01691:160..363,61..236)
                     /EC_number="1.14.17.3"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /codon_start=1
                     /note="alternatively spliced PAM3b protein"
     mat_peptide     join(L01669:24..143,L01670:71..128,L01671:187..274,
                     L01672:89..174,L01673:162..245,L01674:77..125,
                     L01675:163..230,L01676:227..307,L01677:67..143,
                     L01678:186..289,L01680:308..492,L01681:253..324,
                     L01683:65..194,L01684:183..299,L01685:140..212,
                     L01686:52..262,L01687:53..253,L01688:89..204,
                     L01689:60..159,L01690:11..64,61..236)
                     /EC_number="1.14.17.3"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /gene="PAM"
                     /codon_start=1
                     /note="alternatively spliced PAM3 protein"
     CDS             join(L01668:415..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01682:51..365,L01683:65..194,
                     L01684:183..299,L01685:140..212,L01686:52..262,
                     L01687:53..253,L01688:89..204,L01689:60..159,
                     L01690:11..64,L01691:160..363,L01692:219..272,61..239)
                     /EC_number="1.14.17.3"
                     /gene="PAM"
                     /note="alternatively spliced PAM1 protein"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /codon_start=1
                     /translation="MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFS
                     NECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRAS
                     MDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGG
                     ETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGE
                     KVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYP
                     VEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTC
                     TKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQ
                     GDFYSLLSKLLGEREDVHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEH
                     EEWGNAILVRDRIHRFHQLESTLRPAESRAFSFQQPGEGPWEPEPSGDFHVEEELDWP
                     GVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVID
                     PNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSKEGPLLILGRSM
                     QPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQWGEESSGSSPR
                     PGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYI
                     PGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHDIVASEDGTVYI
                     GDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPKVENKPTSSELQKMQEK
                     QKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGDHDRKLESSSGRVLG
                     RFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTESEEEYSAPLPKP
                     APSS"
     CDS             join(L01668:415..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01691:160..363,L01692:219..272,61..239)
                     /EC_number="1.14.17.3"
                     /gene="PAM"
                     /note="alternatively spliced PAM2 protein"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /codon_start=1
                     /translation="MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFS
                     NECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRAS
                     MDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGG
                     ETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGE
                     KVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYP
                     VEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTC
                     TKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQ
                     DFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLG
                     PIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSK
                     EGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQ
                     WGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHAS
                     FGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHD
                     IVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPKVENKP
                     TSSELQKMQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGDHDR
                     KLESSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTES
                     EEEYSAPLPKPAPSS"
     CDS             join(L01668:415..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01692:219..272,61..239)
                     /EC_number="1.14.17.3"
                     /gene="PAM"
                     /note="alternatively spliced PAM3a protein"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /codon_start=1
                     /translation="MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFS
                     NECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRAS
                     MDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGG
                     ETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGE
                     KVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYP
                     VEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTC
                     TKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQ
                     DFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLG
                     PIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSK
                     EGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQ
                     WGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHAS
                     FGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHD
                     IVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKDHDRKLESSSGRVL
                     GRFRGKGSGGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTESEEEYSAPLPK
                     PAPSS"
     CDS             join(L01668:415..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,
                     L01691:160..363,61..239)
                     /EC_number="1.14.17.3"
                     /gene="PAM"
                     /note="alternatively spliced PAM3b protein"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /codon_start=1
                     /translation="MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFS
                     NECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRAS
                     MDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGG
                     ETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGE
                     KVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYP
                     VEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTC
                     TKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQ
                     DFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLG
                     PIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSK
                     EGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQ
                     WGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHAS
                     FGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHD
                     IVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKEAEAVVEPKVENKP
                     TSSELQKMQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRWKKSRAFGGKGS
                     GGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGTESEEEYSAPLPKPAPSS"
     CDS             join(L01668:415..518,L01669:23..143,L01670:71..128,
                     L01671:187..274,L01672:89..174,L01673:162..245,
                     L01674:77..125,L01675:163..230,L01676:227..307,
                     L01677:67..143,L01678:186..289,L01680:308..492,
                     L01681:253..324,L01683:65..194,L01684:183..299,
                     L01685:140..212,L01686:52..262,L01687:53..253,
                     L01688:89..204,L01689:60..159,L01690:11..64,61..239)
                     /EC_number="1.14.17.3"
                     /gene="PAM"
                     /note="alternatively spliced PAM3 protein"
                     /product="peptidylglycine alpha-amidating monooxygenase"
                     /codon_start=1
                     /translation="MAGRARSGLLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFS
                     NECLGTIGPVTPLDASDFALDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRAS
                     MDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGG
                     ETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGE
                     KVVNADISCQYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYP
                     VEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKYALSFMTC
                     TKNVAPDMFRTIPAEANIPIPVKPDMVMMHGHHKEAENKEKSALMQQPKQGEEEVLEQ
                     DFHVEEELDWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLG
                     PIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLDPHSK
                     EGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQ
                     WGEESSGSSPRPGQFSVPHSLALVPHLDQLCVADRENGRIQCFKTDTKEFVREIKHAS
                     FGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHD
                     IVASEDGTVYIGDAHTNTVWKFTLTEKMEHRSVKKAGIEVQEIKGKGSGGLNLGNFFA
                     SRKGYSRKGFDRVSTEGSDQEKDEDDGTESEEEYSAPLPKPAPSS"
BASE COUNT      244 a    220 c    209 g    306 t
ORIGIN      
        1 aaacagactt gtttgtgcaa acttttaact ccactgtgga actgatttct ttccccccag
       61 gaaagggaag cggcggctta aatctgggaa atttctttgc aagtcgaaaa ggctacagca
      121 gaaaagggtt tgaccgagtg agcacagagg ggagtgacca agagaaagat gaggacgacg
      181 gaactgagtc tgaagaggag tactcggccc cgctgcccaa gcctgcacct tcctcctgag
      241 ctccagcctt cgcccgggta gctggactga ggtttaccag gatgcccaga ctccttcccc
      301 tttagcgcgt gtaaagttct gtgcatttga ttgtaaactg tactcgtcag tgtgggactg
      361 tacacacctt atttacttca tttggctccg ttggcttctg ttctctaggt gaggagttcc
      421 ccaccagttc actccagtgc cattgtcttt atatgaactt agcgtagaga agccgccctc
      481 ctcttccaag gtagcgctcc aacccccgag ggaagtttag ctcattcaca tttggagacg
      541 ttttagttgg tggatgtaaa tagccctatt ctctgcttga acacagtatt ctcccagtcc
      601 acacccatcg ccagtgtctt tctttggtgc ctttcctgtt cagcattctc agcctgtggc
      661 agtgaagaga accaacctgc cacacgacga aaagctgcta aatctccttc tattttttta
      721 aaatcactaa cattatattg caatgagaga aattttaaaa agtctctatt taaattcttt
      781 ttttaaattt ctcctcagtt ggtgtgtttc cgggatgtct tatttttaga tggttacact
      841 gttagaacac tatttttcag aatctgaatg taatttgtgt aataaagtgt tttcagagca
      901 ttagcaagtc agtgtatttt gtgatttttt tggcatgtgt acatatttat acacatcttt
      961 agtaattaac acagtcagt
//