From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Vaccina virus genomic DNA
Date: 29 Dec 92 20:59:04 GMT
Distribution: bionet
Checksum: 50297 26

LOCUS       VACDNA      14234 bp ds-DNA             VRL       11-DEC-1992
DEFINITION  Vaccina virus genomic DNA
ACCESSION   X57318
KEYWORDS    RNA polymerase.
SOURCE      Vaccinia virus DNA.
  ORGANISM  Vaccinia virus
            Viridae; ds-DNA enveloped viruses; Poxviridae; Chordopoxvirinae.
REFERENCE   1  (bases 1 to 14234)
  AUTHORS   Amegadzie,B.Y., Cole,N.B., Ahn,B.Y. and Moss,B.A.
  TITLE     Identification, sequence, and expression of the gene encoding a Mr
            35,000 subunit of the vaccinia virus DNA-dependent RNA polymerase
  JOURNAL   J. Biochem. (1992) In press
  STANDARD  full automatic
COMMENT     From EMBL    entry VVDNA;  dated 21-OCT-1992.
FEATURES             Location/Qualifiers
     CDS             complement(<1..603)
                     /codon_start=1
                     /translation="MRRLRDRISDIERQLSDCRRNNESNADMEREMQRLRDRIMDLDR
                     QLNECKRNGNGTSSEEVNRLKTRIRNLKRSLEICSKDESELYSAYKTKLGRAREQISN
                     LQESLRRERESDKTDSYYRRELTRERNKIVELEKELNKCFDAKYIDEINSKKTRISDL
                     ERQLAACKSNGGSNGNMDQYKREIESLKRELAECRRGNNGS"
     CDS             complement(590..2764)
                     /codon_start=1
                     /translation="MEVTNLIEKCTKHSKDFATEVKKLWNDELSSESGLSRKTRNVIR
                     NILRDITKSLTTDKKSKCFRILERSTINGEQIKDVYKTIFNNGVDVESRINTTGKYVL
                     FTVMTYVAAELRLIKSDEIFALLSRFFNMICDIHRKYGCGNMFVGIPAALIILLEIDH
                     INKLFSVFSTRYDAKAYLYTEYFLFLNINHYLLSGSDLFINVAYGAVSFSSPISVPDY
                     IMEALTFKACDHIMKSGDLKYTYAFTKKVKDLFNTKSDSIYQYVRLHEMSYDGVSEDT
                     DDDDEVFAILNLSIDSSVDRYRNRVLLLTPEVASLRKEYSDVEPDYKYLMDEEVPAYD
                     KHLPKPITNTGIEEPHATGGDEDQPIKVVHPPNNDKDDAIKPYNPLEDPNYVPTITRT
                     AIGIADYQLVINKLIEWLDKCEEECGNSGEFKTELEEAKRKLTELNAELSDKLSKIRT
                     LERDSVYKTERIDRLTKEIKEHRDIQNGTDDGSDLLEIDKKTIRELRESLDREREMRS
                     ELEKELDTIRNGKVDGSCQRELELSRMWLKQRDDDLRAEIDKRRNVEWELSRLRRDIK
                     ECDKYKEDLDKAKTTISNYVKQISTLESEIAKYQQDRDTLSVVRRELEEERRVRDLES
                     RLDECTRNQEDTQEVDALRSRIRELENKLTDCIESGGGNLTEISRLQSKISDLERQLS
                     ECRENATEISRLQSRISDLERQLNDCRRNNETNAETERDATS"
     CDS             complement(2809..3645)
                     /codon_start=1
                     /translation="MYYLSISGRFLNDFALLKFTYLGESWTFSLSVPEYILYGLGIFC
                     FRILLKKFSNDAILVYIRTNNRNGYDYVEFNKKGIAKVTEDKPDNDKRIHAIRLINDS
                     TDVQHIHFGFRNMVIIDNECANIQSSAENATDTGHHQDSKINIEDDVIDDDDYNPKPT
                     PIPEPHPRPPFPRHEYHKRPKLLPVEEPDPVKKDADRIRLDNHILNTLDHNLNFIGHY
                     CCDTAAVDRLEHHIETLGQYAVILARKINMQTLLFPWPLPTVHPHAIDGSIPPHGRST
                     IL"
     CDS             complement(3667..4308)
                     /codon_start=1
                     /translation="MANIINLWNGIVPTVQDVNVASITAFKSMIDETWDKKIEANTCI
                     SRKHRNIIHEVIRDFMKAYPKMDENRKSPLGAPMQWLTQYYILKNEYYKTMLAYDNGS
                     LNTKFKTLNIYMITNVGQYILYIVFCIISGKNHDGTPYIYDSEITSNDKNFINERIKY
                     ACKQILHGQLTIALRIRNKFMFIGSPMYLWFNVNGSQVYHDIYIVMPVFIIKR"
     CDS             complement(4358..4690)
                     /codon_start=1
                     /translation="MDGTLFPGDDDLAIPATEFFSTKAAKKPDRKREQIVKADEDDNE
                     ETLKQRLTNLEKKITNVTTKFEQIEKCCKRNDEVLFRLENHAETLRAAMISLAKKIDV
                     QTGRRPYE"
     CDS             complement(4691..5131)
                     /codon_start=1
                     /translation="MNSLSIFFIVVATAAVCLLFIQGYSIYENYGNIKEFNATHAAFE
                     YSKSIGGTPALDRRVQDVNDTISDVKQKWRCVVYPGNGFVSASIFGFQAEVGPNNTRS
                     IRKFNTMQQCIDFTFSDVININIYNPCVVPNINNAECQFLKSVL"
     CDS             complement(5132..6049)
                     /gene="RPO35"
                     /evidence="EXPERIMENTAL"
                     /product="RNA polymerase subunit"
                     /codon_start=1
                     /translation="MQHPREENSIVVELEPSLATFIKQGFNNLVKWPLLNIGIVLSNT
                     STAVNEEWLTAVEHIPTMKIFYKHIHKILTREMGFLVYLKRSQSERDNYITLYDFDYY
                     IIDKDTNSVTMVDKPTELKETLLHVFQEYRLKSSQTIELIAFSSGTVINEDIVSKLTF
                     LDVEVFNREYNNVKTIIDPDFVFRSPFIVISPMGKLTFFVEVYSWFDFKSCLKDIIDF
                     LEGALIANIHNHMIKVGNCDETVSSYNPESGMLFVNDLMTMNIVNFFGCNSRLESYHR
                     FDMTKVDVELFIKALSDACKKILSASNRL"
     CDS             complement(6012..6245)
                     /codon_start=1
                     /translation="MEDLNEANFSHLLINLSNNKDIDAQYASTLSVVHELLSAINFKI
                     FNINKKSKKNSKSIEQHPVVHHAASAGREFNRR"
     CDS             6405..6779
                     /codon_start=1
                     /translation="MASILNTLRFLEKTSFYNCNDSITKEKIKIKHKGMSFVFYKPKH
                     STVVKYLSGGGIYHDDLVVLGKVTINNLKMMLFYMDLSYHGVTSSGAIYKLGSSIDRL
                     SLNRTIVTKVNNYDDTFFDDDD"
     CDS             complement(6746..7558)
                     /codon_start=1
                     /translation="MNCFQEKQFSRENLLKMPFRMVLTGGSGSGKTIYLLSLFSTLVK
                     KYKHIFLFTPVYNPDYDGYIWPNHINFVSSQESLEYNLIRTKSNIEKCIAVAQNHKKS
                     AHFLLIFDDVGDKLSKCNTLIEFLNFGRHLNTSIILLCQTYRHVPILGRANITHFCSF
                     NISISDAENMLRSMPVKGKRKDILNMLNMIQTARSNNRLAIIIEDSVFCEGELRICTD
                     TADKDVIEQKLNIDILVNQYSHMKKNLNAILESKKTKLCNSDQSSSSKNVSS"
     CDS             7676..8233
                     /codon_start=1
                     /translation="MMTPENDEEQTSVFSATVYGDKIQGKNKRKRVIGLCIRISMVIS
                     LLSMITMSAFLIVRLNQCMSANEAAITDAAVAVAAASSTHRKVASSTTQYDHKESCNG
                     LYYQGSCYILHSDYQLFSDAKANCTAESSTLPNKSDVLITWLIDYVEDTWGSDGNPIT
                     KTTSDYQDSDVSQEVRKYFCVKTMN"
     CDS             8807..9337
                     /codon_start=1
                     /translation="MDAAFVITPMGVLTITDTLYDDLDISIMDFIGPYIIGNIKTVQI
                     DVRDIKYSDMQKCYFSYKGKIVPQDSNDLARFNIYSICAAYRSKNTIIIACDYDIMLD
                     IEDKHQPFYLFPSIDVFNATIIEAYNLYTAGDYHLIINPSDNLKMKLLFNSSFCISDG
                     NGWIIIDGKCNSNFLS"
     CDS             9404..10069
                     /codon_start=1
                     /translation="MMLVPLITVTVVAGTILVCYILYICRKKIRTVYNDNKIIMTKLK
                     KIKSSNSSKSSKSTDSESDWEDHCSAMEQNNDVDNISRNEILDDDSFAGSLIWDNESN
                     VMAPSTEHIYDSVAGSTLLINNDRNEQTIYQNTTVVINETETVEVLNEDTKQNPNYSS
                     NPFVNYNKTSICSKSNPFITELNNKFSENNPFRRAHSDDYLNKQEQDHEHDDIESSVV
                     SLV"
     CDS             10133..10924
                     /codon_start=1
                     /translation="MEIFPVFGISKISNFIANNDCRYYIDTEHQKIISDEINRQMDET
                     VLLTNILSVEVVNDNEMYHLIPHRLSTIILCISSVGGCVISIDNDINDKNILTFPIDH
                     AVIISPLSKCVVVSKGPTTILVVKADIPSKRLVTSFTNDILYVNNLSLINYLPLSVFI
                     IRRVTDYLDRHICDQIFANNKWYSIITIDDKQYPIPSNCIGMSSAKYINSSIEQDTLI
                     HVCNLEHPFDLVYKKMQSYNSVPIKEQILYGRIDNINMSISISVD"
     CDS             complement(11220..12053)
                     /codon_start=1
                     /translation="MSRVRISLIYLCTFMIITSTKTIEYTACNNTIIIPCTIDNPTKY
                     IRWKLDNHDILTYNKTSKTTILSKWHTSARLHSLSDSDVSLIIEYKDILPGTYTCEDN
                     TGIKSTVKLVQRHTNWFNDYQTMLMFIFTGITLFLLFLEITYTSISVVFSTNLGILQV
                     FGCVIAMIELCGAFLFYPSMFTLRHIIGLLMMTLPSIFLIITKVFSFWLLCKLSCAVH
                     LIIYYQLAGYILTVLGLGLSLKECVDGTLLLSGLGTIMVSEHFSLLFLVCFPSTQRDY
                     Y"
     CDS             11956..13281
                     /codon_start=1
                     /translation="MMVLLHAVYSIVFVDVIIIKVQRYINDILTLDIFYLFKMIPLLF
                     ILFYFANGIEWHKFETSEEIISTYLLDDVLYTGVNGAVYTFSNNKLNKTGLTNNNYIT
                     TSIKVEDADKDTLVCGTNNGNPKCWKIDGSDDPKHRGRGYAPYQNSKVTIISHNGCVL
                     SDINISKEGIKRWRRFDGPCGYDLYTADNVIPKDGLRGAFVDKDGTYDKVYILFTDTI
                     GSKRIVKIPYIAQMCLNDEGGPSSLSSHRWSTFLKVELECDIDGRSYRQIIHSRTIKT
                     DNDTILYVFFDSPYSKSALCTYSMNTIKQSFSTSKLEGYTKQLPSPASGICLPAGKVV
                     PHTTFEVIEKYNVLDDIIKPLSNQPIFEGPSGVKWFDIKEKENEHREYRIYFIKENSI
                     YSFDTKSKQTRSSQVDARLFSVMVTSKPLFIADIGIGVGMPQMKKILKM"
     CDS             13307..13813
                     /codon_start=1
                     /translation="MNKHKTDYAGYACCVICGLIVGIIFTATLLKVVERKLVHTPSID
                     KTIKDAYIREDCPTDWISYNNKCIHLSTDRKTWEEGRNACKALNPNSDLIKIETPNEL
                     SFLRSIRRGYWVGESEILNQTTPYNFIAKNATKNGNIFVAQRILPNCIRVTLYNNYTT
                     FLSYHYFG"
BASE COUNT     4640 a   2477 c   2325 g   4792 t
ORIGIN      
        1 ggatccattg ttaccacgtc tacactcggc gagctcgcgt ttaagagatt caatttcccg
       61 tttgtattgg tccatgtttc cattgctacc accattagat ttacaggctg ctagttgtcg
      121 ttcgagatca gaaatacggg ttttcttgga attgatttcg tcgatgtact tggcatcgaa
      181 acacttatta agttcttttt ccaattctac gattttattt ctttcgcgag tcaattccct
      241 cctgtagtaa ctatctgttt tgtcagattc acgctctcta cgtagacttt cttgcaagtt
      301 actaatttgt tccctagcac gtccgagttt agttttatat gctgaataga gttctgattc
      361 atcctttgag cagatctcta gcgatcgttt aagattcctg attctagtct ttagcctatt
      421 tacctcctca gaagatgttc cgttaccgtt gcgtttacac tcgttaagct gtctatcaag
      481 atccatgatt ctatctctaa gacgttgcat ctctctttcc atatcagcat tgctttcatt
      541 attacgtctg cagtcactca actgtctttc aatatctgag attctatctc taagacgtcg
      601 catctctctc tgtttcggca ttggtttcat tattacgtct acagtcgttc aactgtcttt
      661 caagatctga tattctagat tggagtctgc taatctctgt agcattttca cggcattcac
      721 tcagttgtct ttcaagatct gagattttag attggagtct gctaatctct gtaagatttc
      781 ctcctccgct ctcgatgcag tcggtcaact tattctctag ttctctaata cgcgaacgca
      841 gtgcatcaac ttcttgcgtg tcttcctggt tgcgtgtaca ttcatcgagt ctagattcga
      901 gatctctaac gcgtcgttct tcctcaagtt ctctgcgtac tacagaaagc gtgtccctat
      961 cttgttgata tttagcaatt tctgattcta gagtactgat ttgctttacg tagttactaa
     1021 tagttgtctt ggccttatca agatcctcct tgtatttgtc gcattccttg atatccctac
     1081 gaagtctgga cagttcccat tcgacattac gacgtttatc gatttcagct cggagatcgt
     1141 catcgcgttg ttttagccac atacgactga gttcaagttc tcgttgacaa gatccatcta
     1201 cttttccatt cctaatagta tccagttcct tttctagttc tgaacgcatt tctcgttccc
     1261 tatcaagcga ttctctcaat tctcggatag tcttcttatc aatttctaat aaatctgaac
     1321 catcatctgt cccattttga atatccctgt gttctttgat ctcttttgta agtcggtcga
     1381 ttctttcggt tttataaaca gaatcccttt ccaaagtcct aatcttactg agtttatcac
     1441 taagttctgc attcaattcg gtgagttttc tcttggcttc ttccaactct gttttaaact
     1501 ctccactatt tccgcattct tcctcgcatt tatctaacca ttcaattagt ttattaataa
     1561 ctagttggta atcagcgatt cctatagccg ttcttgtaat tgtgggaaca taattaggat
     1621 cttctaatgg attgtatggc ttgatagcat catctttatc attattaggg ggatggacaa
     1681 ccttaattgg ttggtcctca tctcctccag tagcgtgtgg ttcttcaata ccagtgttag
     1741 taataggctt aggcaaatgc ttgtcgtacg cgggcacttc ctcatccatc aagtatttat
     1801 aatcgggttc tacgtctgaa tattcttttc taagagacgc gacttcggga gttagtagaa
     1861 gaactctgtt tctgtatcta tcaacgctgg aatcaatact caagttaagg atagcgaata
     1921 cctcatcgtc atcatccgta tcttctgaaa caccatcata tgacatttca tgaagtctaa
     1981 cgtattgata aatagaatca gatttagtat taaacagatc cttaaccttt ttagtaaacg
     2041 catatgtata ttttagatct ccagatttca taatatgatc acatgcctta aatgtcagtg
     2101 cttccatgat ataatctgga acactaatgg gtgacgaaaa agatacagca ccatatgcta
     2161 cgttgataaa taaatctgaa ccactaagta gataatgatt aatgttaagg aagaggaaat
     2221 attcagtata tagatatgcc ttagcatcat atcttgtact aaacacgcta aacagtttat
     2281 tgatgtgatc aatttccaac agaataatta gagcagcggg aataccaaca aacatattac
     2341 cacatccgta ttttctatga atatcacata tcatgttaaa aaatcttgat agaagagcga
     2401 atatctcgtc tgacttaatg agtcgtagtt cagcagcaac ataagtcata actgtaaata
     2461 gaacatactt tcctgtagtg ttgattctag actccacatc aacaccatta ttaaaaatag
     2521 ttttatatac atctttaatc tgctctccgt taatcgtcga acgttctagt atacggaaac
     2581 actttgattt cttatctgta gttaatgact tagtgatatc acgaagaata ttacgaatta
     2641 catttcttgt ttttcttgag agacctgatt cagaactcaa ctcatcgttc catagttttt
     2701 ttacctcagt ggcgaaatct ttggagtgct tggtacattt ttcaataagg ttcgtgacct
     2761 ccatttatta taaaaaattt tattcaaaac ttaactacaa tcgggtaatt ataaaatcgt
     2821 agatctccca tgtggtggaa tactaccatc tatcgcatgt ggatggacag taggtaatgg
     2881 ccatgggaac agtaatgttt gcatatttat ctttcttgcc agtattactg catattgtcc
     2941 caatgtttcg atgtgatgtt ctaacctatc aactgccgct gtatcacaac aatagtgtcc
     3001 gatgaaatta agattatgat ccaatgtgtt taatatatga ttatcaagtc ttatacgatc
     3061 cgcgtctttt ttgacaggat caggttcttc tacaggaaga agtttcggcc tcttatgata
     3121 ttcatgtctg ggaaacggtg gtctagggtg aggctccggt atcggagtgg gttttggatt
     3181 ataatcatca tcgtctatga catcatcttc gatatttatt ttgctatctt gatgatgtcc
     3241 tgtatcagtt gcattttcag cactcgactg aatattagcg cattcattgt ctattattac
     3301 catatttcta aacccaaaat gtatgtgttg aacatcagta ctatcgttga tgagtcttat
     3361 agcatgaatt cgcttatcgt tatcgggttt atcttctgtc accttagcaa ttcctttttt
     3421 attaaactct acataatcat atccatttct attgtttgtt ctaatataaa cgagtatagc
     3481 atcattgcta aattttttca atagtatgcg aaaacagaat atacctaaac catataatat
     3541 atattcaggg acactcaaac taaatgtcca ggattctcct aaatacgtaa actttaatag
     3601 tgcgaaatca ttcaaaaatc taccacttat agatagatag tacataaata gcgtatagta
     3661 gtctacctat ctctttatta tgaaaaccgg cattacgata tatatgtcgt gatatacctg
     3721 tgatccgttt acgttaaacc ataaatacat gggtgatcct ataaacatga atttatttct
     3781 aattctcaga gctatagtta attgaccgtg taatatttgc ttacatgcat acttgatacg
     3841 ctcattaata aaatttttat cattgctcgt tatctcagaa tcgtatatat aaggagtacc
     3901 atcgtgattc ttaccagata ttatacaaaa tactatatat aaaatatatt gaccaacgtt
     3961 agtaatcata taaatgttta acgttttaaa ttttgtattc aatgatccat tatcatacgc
     4021 tagcatggtc ttgtaatatt cattctttaa aatataatat tgtgttagcc attgcattgg
     4081 agctcctaat ggagattttc tattctcatc cattttagga taggctttca taaagtccct
     4141 aataacttcg tgaataatgt ttctatgttt tctactgatg catgtatttg cttcgatttt
     4201 tttatcccat gtttcatcta tcatagattt aaacgcagta atgctcgcaa cattaacatc
     4261 ttgaaccgtt ggtacaattc cgttccataa atttataatg ttcgccattt atataactca
     4321 ttttttgaat atacttttaa ttaacaaaag agttaagtta ctcatatggg cgccgtccag
     4381 tctgaacatc aatcttttta gccagagata tcatagccgc tcttagagtt tcagcgtgat
     4441 tttccaacct aaatagaact tcatcgttgc gtttacaaca cttttctatt tgttcaaact
     4501 ttgttgttac attagtaatc tttttttcca aattagttag ccgttgtttg agagtttcct
     4561 cattgtcgtc ttcatcggct ttaacaatct gttcgcgttt ccgatctggc tttttagcag
     4621 cctttgtaga aaaaaattca gttgctggaa ttgcaagatc gtcatctccg gggaaaagag
     4681 ttccgtccat ttaaagtaca gattttagaa actgacactc tgcgttattt atatttggta
     4741 caacacatgg attataaata ttgatgttaa taacatcaga aaatgtaaag tctatacatt
     4801 gttgcatcgt gttaaatttt ctaatggatc tagtattatt gggtccaact tctgcctgaa
     4861 atccaaatat ggaagcggat acaaaaccgt ttcctggata aaccacacat ctccactttt
     4921 gctttacatc agaaattgtg tcgttgacat cttgaactct cctatctaat gccggtgttc
     4981 cacctataga ttttgaatat tcgaatgctg catgagtagc attaaattcc ttaatattgc
     5041 cataattttc atatattgag taaccctgga taaaaagtaa acacaccgca gccgtcgcta
     5101 ccacaataaa aaaaattgat agagagttca tttataatct attagaagct gacaaaattt
     5161 ttttacacgc atcagacaat gctttaataa atagttcaac atctactttt gtcatatcga
     5221 accgatggta tgattctaac ctagaattac atccgaaaaa gttgactatg ttcatagtca
     5281 ttaagtcatt aacaaacaac attccagact ctggattata agacgatact gtttcgtcac
     5341 aattacctac cttaatcatg tgattatgaa tattggctat tagagcacct tctaagaaat
     5401 ctataatatc tttcaaacac gatttaaaat caaaccacga atatacttct acgaagaaag
     5461 ttagtttacc cataggagaa ataactataa atggagatct aaatacaaaa tccggatcta
     5521 tgatagtttt aacattatta tattctctat taaatacctc cacatctaaa aatgttaatt
     5581 ttgaaactat gtcttcgttt attaccgtac ctgaactaaa cgctataagc tctattgttt
     5641 gagaactctt taaacgatat tcttgaaata catgtaacaa agtttccttt aactcggtcg
     5701 gtttatctac catagttaca gaatttgtat ccttatctat aatataataa tcaaaatcgt
     5761 ataaagttat ataattatcg cgttcagatt gggatctttt caaatagact aaaaacccca
     5821 tttctctagt aagtatctta tgtatatgtt tgtaaaatat cttcatggtt ggaatatgct
     5881 ctaccgcagt tagccattcc tcattgacag cggtagatgt attagacaaa actattccaa
     5941 tgtttaacaa gggccatttt acgagattat taaatccttg tttgataaat gtagccaatg
     6001 agggttcgag ttcaacgacg attgaattct cttcccgcgg atgctgcatg atgaacgacg
     6061 ggatgttgtt cgattgattt ggaattcttt ttcgactttt tgtttatatt aaatatttta
     6121 aaatttatag cggatagcaa ttcatgtacc acggataatg tagacgcgta ttgcgcatcg
     6181 atatctttat tattagataa atttatcaat aaatgtgaga agtttgcctc gttaaggtct
     6241 tccatttaaa tattatataa acatttgtgt ttgtaactta ttcgtctttt atggaatagt
     6301 tttttactag taaagctgca attacacact ttgtccgtaa aacataaata taaacaccag
     6361 cttttatcaa tcgttccaaa aagtcgacgg cggacatttt taacatggca tctattttaa
     6421 atacacttag gtttttggaa aaaacatcat tttataattg taacgattca ataactaaag
     6481 aaaagattaa gattaaacat aagggaatgt catttgtatt ttataagcca aagcattcta
     6541 ccgttgttaa atacttgtct ggaggaggta tatatcatga tgatttggtt gtattgggga
     6601 aggtaacaat taataatcta aagatgatgc tattttacat ggatttatca tatcatggag
     6661 tgacaagtag tggagcaatt tacaaattgg gatcgtctat cgatagactt tctctaaata
     6721 ggactattgt tacaaaagtt aataattatg atgatacatt ttttgacgac gatgattgat
     6781 cgctattgca caattttgtt tttttacttt ctaatatagc gtttagattc tttttcatgt
     6841 gcgaatattg atttactaaa atatcgatgt ttaacttttg ttctatgacg tccttatcag
     6901 cggtatcggt acatatacgt aattcacctt cacaaaatac ggagtcttcg ataataatag
     6961 ccaatcgatt attggatcta gctgtctgta tcatattcaa catgtttaat atatcctttc
     7021 gtttcccctt tacaggcatc gatcgtagca tattttccgc gtctgagatg gaaatgttaa
     7081 aactacaaaa atgcgtaatg ttagcccgtc ctaatattgg tacgtgtcta taagtttggc
     7141 atagtagaat aatagacgtg tttaaatgcc ttccaaagtt taagaattct attagagtat
     7201 tgcattttga tagtttatca cctacatcat caaaaataag taaaaagtgt gctgattttt
     7261 tatgattttg tgcgacagca atacattttt ctatgttact tttagttcgt atcagattat
     7321 attctagaga ttcctgacta ctaacgaaat taatatgatt tggccaaatg tatccatcat
     7381 aatctgggtt ataaacgggt gtaaacaaga atatatgttt atatttttta actagtgtag
     7441 aaaacagaga tagtaaatag atagtttttc cagatccaga tcctcccgtt aaaaccattc
     7501 taaacggcat ttttaataaa ttttctcttg aaaattgttt ttcttggaaa caattcataa
     7561 ttatatttac agttactaaa ttaatttgat aataaatcaa aatatggaaa actaaggtcg
     7621 ttagtaggga ggagaacaaa gaaggcacat cgtgacataa ataacattta ttatcatgat
     7681 gacaccagaa aacgacgaag agcagacatc tgtgttctcc gctactgttt acggagacaa
     7741 aattcaagga aagaataaac gcaaacgcgt gattggtcta tgtattagaa tatctatggt
     7801 tatttcacta ctatctatga ttaccatgtc cgcgtttctc atagtgcgcc taaatcaatg
     7861 catgtctgct aacgaggctg ctattactga cgccgctgtt gccgttgctg ctgcatcatc
     7921 tactcataga aaggttgcgt ctagcactac acaatatgat cacaaagaaa gctgtaatgg
     7981 tttatattac cagggttctt gttatatatt acattcagac taccagttat tctcggatgc
     8041 taaagcaaat tgcactgcgg aatcatcaac actacccaat aaatccgatg tcttgattac
     8101 ctggctcatt gattatgttg aggatacatg gggatctgat ggtaatccaa ttacaaaaac
     8161 tacatccgat tatcaagatt ctgatgtatc acaagaagtt agaaagtatt tttgtgttaa
     8221 aacaatgaac taatatttat ttttgtacat taataaatga aatcgcttaa tagacaaact
     8281 gtaagtaggt ttaagaagtt gtcggtgccg gccgctataa tgatgatact ctcaaccatt
     8341 attagtggca taggaacatt tctgcattac aaagaagaac tgatgcctag tgcttgcgcc
     8401 aatggatgga tacaatacga taaacattgt tatttagata ctaacattaa aatgtctaca
     8461 gataatgcgg tttatcagtg tcgtaaatta cgagccagat tgcctagacc ggatactaga
     8521 catctgagag tattgtttag tattttttat aaagattatt gggtaagttt aaaaaagacc
     8581 aatgataaat ggttagatat taataatgat aaagatatag atattagtaa attaacaaat
     8641 tttaaacaac taaacagtac gacggatgct gaagcgtgtt atatatacaa gtctggaaaa
     8701 ctggttaaaa cagtatgtaa aagtactcaa tctgtactat gtgttaaaaa attctacaag
     8761 tgacaacaaa aaatgaatta ataataagtc gttaacgtac gccgccatgg acgccgcgtt
     8821 tgttattact ccaatgggtg tgttgactat aacagataca ttgtatgatg atctcgatat
     8881 ctcaatcatg gactttatag gaccatacat tataggtaac ataaaaactg tccaaataga
     8941 tgtacgggat ataaaatatt ccgacatgca aaaatgctac tttagctata agggtaaaat
     9001 agttcctcag gattctaatg atttggctag attcaacatt tatagcattt gtgccgcata
     9061 cagatcaaaa aataccatca tcatagcatg cgactatgat atcatgttag atatagaaga
     9121 taaacatcag ccattttatc tattcccatc tattgatgtt tttaacgcta caatcataga
     9181 agcgtataac ctgtatacag ctggagatta tcatctaatc atcaatcctt cagataatct
     9241 gaaaatgaaa ttgttgttta attcttcatt ctgcatatca gacggcaatg gatggatcat
     9301 aattgatggg aaatgcaata gtaatttttt atcataaaag ttgtaaagta aataataaaa
     9361 caataaatat tgaactagta gtacgtatat tgagcaatca gaaatgatgc tggtacctct
     9421 tatcacggtg accgtagttg cgggaacaat attagtatgt tatatattat atatttgtag
     9481 gaaaaagata cgtactgtct ataatgacaa taaaattatc atgacaaaat taaaaaagat
     9541 aaagagttct aattccagca aatctagtaa atcaactgat agcgaatcag actgggagga
     9601 tcactgtagt gctatggaac aaaacaatga cgtagataat atttctagga atgagatatt
     9661 ggacgatgat agcttcgctg gtagtttaat atgggataac gaatccaatg tcatggcgcc
     9721 tagcacagaa cacatttacg atagtgttgc tggaagcacg ctgctaataa ataatgatcg
     9781 taatgaacag actatttatc agaacactac agtagtaatt aatgagacgg agactgttga
     9841 agtacttaat gaagatacca aacagaatcc taactattca tccaatcctt tcgtaaatta
     9901 taataaaacc agtatttgta gcaagtcaaa tccgttcatt acagaactta acaataaatt
     9961 tagtgagaat aatccgttta gacgagcaca tagcgatgat tatcttaata agcaagaaca
    10021 agatcatgaa cacgatgata tagaatcatc ggtcgtatca ttggtgtgat tagtttcctt
    10081 tttataaaat tgaagtaata tttagtatta ttgctgccgt cacgttgtac aaatggagat
    10141 attccctgta ttcggcattt ctaaaattag caattttatt gctaataatg actgtagata
    10201 ttatatagat acagaacatc aaaaaattat atctgatgag atcaatagac agatggatga
    10261 aacggtactt cttaccaaca tcttaagcgt agaagttgta aatgacaatg agatgtacca
    10321 tcttattccc catagactat cgactattat actctgtatt agttctgtcg gaggatgtgt
    10381 tatctctata gataatgaca tcaatgacaa aaatattcta acatttccca ttgatcatgc
    10441 tgtaatcata tccccactga gtaaatgtgt cgtagttagc aagggtccta caaccatatt
    10501 ggttgttaaa gcggatatac ccagcaaacg attggtaaca tcgtttacaa acgacatact
    10561 gtatgtaaac aatctgtcac tgattaatta tttgccgttg tctgtattca ttattagacg
    10621 agtcaccgac tatttggata gacacatatg cgatcagata tttgcgaata ataagtggta
    10681 ttccattata accatcgacg ataagcaata tcctattcca tcaaactgta taggtatgtc
    10741 ctctgccaag tacataaatt ctagcatcga gcaagatact ttaatacatg tttgtaacct
    10801 cgagcatcca ttcgacttag tatacaaaaa aatgcagtcg tacaattctg tacctatcaa
    10861 ggaacaaata ttgtacggta gaattgataa tataaatatg agcattagta tttctgtgga
    10921 ttaatagatt tctagtatgg ggatcattaa tcatctctaa tctctaaata cctcataaaa
    10981 cgaaaaaaat actgctacaa atgaaaaaaa agctattatc aaatactgta cggaatggat
    11041 tcattctctt ctctttttat gaaactctgt tgtatatcta ctgataaaac tggaagcaaa
    11101 aaatctgata aaaagaataa gaataagatc aaggattata tggaacacga ttattataaa
    11161 ataacaatag ttcctggttc ctcttccacg tctactagct cgtggtatta tacacatgcc
    11221 tagtaatagt ctctttgcgt tgacggaaag cagactagaa ataacaggct aaaatgttca
    11281 gacaccataa tagttcccaa cccagataat aacagagtac catcaacaca ttcctttaaa
    11341 ctcaatccca aacccaaaac cgttaaaatg tatccggcca attgatagta gataatgagg
    11401 tgtacagcgc atgataattt acacagtaac caaaatgaaa atactttagt aattataaga
    11461 aatatagatg gtaacgtcat catcaacaat ccaataatat gccggagagt aaacattgac
    11521 ggataaaaca aaaatgctcc gcataactct atcatggcaa taacacaacc aaatacttgt
    11581 aagattccta aattagtaga aaatacaacg gatatcgatg tataagtgat ctcgagaaat
    11641 aataagaata aagtaatgcc cgtaaagata aacatcaaca ttgtttggta atcattaaac
    11701 caattagtat gacgttgaac taatttcaca gtagatttta ttccagtgtt atcctcgcat
    11761 gtatacgtac ctggtaagat atctttatat tctataatca atgagacatc actatccgat
    11821 aacgaatgaa gtctagcact agtatgccat ttacttaata tggtcgtctt ggaagtttta
    11881 ttataagtta aaatatcatg gttgtccaat ttccatctaa tatactttgt cggattatct
    11941 atagtacacg gaataatgat ggtattatta catgctgtat actctatagt ctttgtagat
    12001 gttataatca taaaagtaca gaggtatatc aacgatattc taactcttga cattttttat
    12061 ttatttaaaa tgataccttt gttatttatt ttattctatt ttgctaacgg tatcgaatgg
    12121 cataagtttg aaacgagtga agaaataatt tctacttact tattagacga cgtattatac
    12181 acgggtgtta atggggcggt atacacattt tcaaataata aactaaacaa aactggttta
    12241 actaataata attatataac aacatctata aaagtagagg atgcggataa ggatacatta
    12301 gtatgcggaa ccaataacgg aaatcccaaa tgttggaaaa tagacggttc agacgaccca
    12361 aaacatagag gtagaggata cgctccttat caaaatagca aagtaacgat aatcagtcac
    12421 aacggatgtg tactatctga cataaacata tcaaaagaag gaattaaacg atggagaaga
    12481 tttgacggac catgtggtta tgatttatac acggcggata acgtaattcc aaaagatggt
    12541 ttacgaggag cattcgtcga taaagatggt acttatgaca aagtttacat tcttttcact
    12601 gatactatcg gctcaaagag aattgtcaaa attccgtata tagcacaaat gtgcctaaac
    12661 gacgaaggtg gtccatcatc attgtctagt catagatggt cgacgtttct caaagtcgaa
    12721 ttagaatgtg atatcgacgg aagaagttat agacaaatta ttcattctag aactataaaa
    12781 acagataatg atacgatact atatgtattc ttcgatagtc cttattccaa gtccgcatta
    12841 tgtacctatt ctatgaatac cattaaacaa tctttttcta cgtcaaaatt ggaaggatat
    12901 acaaagcaat tgccgtcgcc agcctctggt atatgtctac cagctggaaa agttgttcca
    12961 cataccacgt ttgaagtcat agaaaaatat aatgtactag atgatattat aaagccttta
    13021 tctaaccaac ctatcttcga aggaccgtct ggtgttaaat ggttcgatat aaaggagaag
    13081 gaaaatgaac atcgggaata tagaatatac ttcataaaag aaaattctat atattcgttc
    13141 gatacaaaat ctaaacaaac tcgtagctcg caagtcgatg cgcgactatt ttcagtaatg
    13201 gtaacttcga aaccgttatt tatagcagat atagggatag gagtaggaat gccacaaatg
    13261 aaaaaaatac ttaaaatgta atcttaatcg agtacaccac acgacaatga acaaacataa
    13321 gacagattat gctggttatg cttgctgcgt aatatgcggt ctaattgttg gaattatttt
    13381 tacagcgaca ctattaaaag ttgtagaacg taaattagtt catacaccat caatagataa
    13441 aacgataaaa gatgcatata ttagagaaga ttgtcctact gactggataa gctataataa
    13501 taaatgtatc catttatcta ctgatcgaaa aacctgggag gaaggacgta atgcatgcaa
    13561 agctctaaat ccaaattcgg atctaattaa gatagagact ccaaacgagt taagtttttt
    13621 aagaagcatt agacgcggat attgggtagg agaatccgaa atattaaacc agacaacccc
    13681 atataatttt atagctaaga atgccacgaa gaatggaaat atatttgtag cacaacgaat
    13741 actcccaaac tgcattcgtg ttacactata taacaattac actacatttt tatcatacca
    13801 ctacttcggt tagatgtttt agaaaaaaat aaatatcgcc gtaccgttct tgtttttata
    13861 aaaataacaa ttaacaatta tcaaattttt tctttaatat tttacgtggt tgaccattct
    13921 tggtggtaaa ataatctctt agtgttggaa tggaatgctg tttaatgttt ccacactcat
    13981 cgtatatttt gacgtatgta gttcgtatca catcgtttac ccaatagtca gactgtagtt
    14041 ctatcatgct tcctacatta gaaggaggaa cagttttaaa gtctcttggt tttaatctat
    14101 agccgttagt tttcatgaaa tcctttgttt tatccacttc acattttaaa taaatgtcca
    14161 ctatacattc ttctgttaat tttactagat cgtcatgggt catagaattt ataggttccg
    14221 tagtccatgg atcc
//