From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat potassium channel (Kv2.2; CDRK) mRNA, complete cds.
Date: 22 Dec 92 22:47:01 GMT
Distribution: bionet
Checksum: 58421 7

LOCUS       RATCDRK      3232 bp ss-mRNA            ROD       23-NOV-1992
DEFINITION  Rat potassium channel (Kv2.2; CDRK) mRNA, complete cds.
ACCESSION   M77482
KEYWORDS    potassium channel protein; transmembrane protein.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) brain cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3232)
  AUTHORS   Hwang,P.M., Glatt,C.E., Bredt,D.S., Yellen,G. and Snyder,S.H.
  TITLE     A novel potassium channel with unique localization in mammalian
            brain: molecular cloning and characterization
  JOURNAL   Neuron 8, 473-481 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            <1..>3232
                     /gene="Kv2.2"
     CDS             327..2735
                     /gene="Kv2.2"
                     /product="potassium channel"
                     /codon_start=1
                     /translation="MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGL
                     NHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNF
                     YRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMR
                     DGEGEEFDNTCCPEKRKKLWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPEL
                     QENDEFGQPSDNRKLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILP
                     YYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNE
                     LGLLILFLAMGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTL
                     LGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIV
                     SMNLKDAFARSMELIDVAVEKAGESANIKDSVDDNHLSPSRWKWARKALSETSSNKSY
                     ENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKLEMLYNEITKTQTHSHPNPDCQEQPER
                     PSAYEEEIEMEEVVCPQEQLAVAQTEVIVDMKSTSSIDSFTSCATDFTETERSPLPPP
                     SASHLQMKFPTDLPGMDEHQRVRAPPFLTLSRDKGPAAREAALDYAPIDITVNLDAGA
                     SHGPLQPDSASDSPKSSLKGSNPLKSRSLKVNFQENRGSAPQTPPSTARPLPVTTADF
                     PLTTPQHMSTILLEEALPQGQRPCRGLMFQHTVRDHPKVYPHEFPSKNCFLSLLEKGG
                     ASLK"
BASE COUNT      911 a    833 c    808 g    680 t
ORIGIN      
        1 acgtggcaga accggagtga gggatgtaaa gaagggagga ggaaagctgc caggagctcc
       61 agccagtcgg ggagaccctc ctctctgtgg aggggagggg gatttccagc gacacatcat
      121 tggcgaaagg gacctttgca ggagaggagt cctctgaggg aacagggaat cccacagccc
      181 cctgtggcac aggagccaga gctgctgccc gagcggagct gggtccgtgg gagctagctg
      241 atgtggcaat gcctgttcca gtggaatcct gcttcaggtg acctcctttc taaggaccct
      301 agctctgtgg ctctgtccag ttcaaaatgg cagaaaaggc acctcctggc ttgaacagaa
      361 aaacatccag gtcaacactt tctcttcctc cagaaccagt ggacattatc cgaagcaaaa
      421 catgctctcg gagagttaag atcaacgtag ggggccttaa ccacgaagtc ctgtggagaa
      481 ctctggacag gctacccagg acgcgcctgg ggaagctccg agactgtaac acgcacgaga
      541 gtctcctgga ggtgtgcgat gactacaacc ttaatgagaa tgagtatttc ttcgaccgcc
      601 atcctggagc cttcacatct attctgaact tctaccggac gggaaagctc cacatgatgg
      661 aagaaatgtg tgccctctcc tttggccaag agcttgatta ctggggcatc gatgagatct
      721 acctagagtc ctgctgccaa gccagatacc atcagaagaa ggagcagatg aacgaagaac
      781 ttagaaggga ggcagagacc atgcgtgacg gcgaggggga ggagtttgat aacacctgct
      841 gcccagagaa aaggaagaaa ctttgggact tgctggagaa gccgaactca tccgtggcgg
      901 caaagatcct ggccatcgtg tctatcctgt tcatcgtcct ttccaccatt gctctgtctc
      961 tcaacacact tccggagctg caagaaaacg atgaatttgg gcaacccagt gacaaccgga
     1021 agttggcgca cgtagaggct gtgtgcattg cttggtttac catggagtac cttttacgat
     1081 tcctgtcctc accaaataaa tggaaattct ttaaaggccc actgaatgtc attgacctcc
     1141 tggccatctt gccatactat gtaaccatct tcctcaccga gtccaacaaa agtgtgctgc
     1201 agttccagaa tgtgagacgc gtggtccaga tctttcgaat catgcgcatc ctcaggatcc
     1261 tgaaactcgc cagacactcg acgggcctgc agtctctggg tttcaccctc aggcggagtt
     1321 acaatgagtt gggtttatta atactgtttc tggccatggg aataatgata ttttccagtt
     1381 tggtgttttt cgctgagaaa gatgaagatg ctacaaagtt caccagtatc cctgcatcat
     1441 tttggtgggc taccatcacc atgaccactg tgggctatgg tgacatttac cctaaaacac
     1501 tgttagggaa aattgtgggt ggcctttgct gcattgcagg agtcctggtt attgcccttc
     1561 ctatccccat cattgtgaac aatttctctg agttctataa ggaacaaaaa cgccaggaga
     1621 aagctattaa aaggagagag gctcttgaaa gagccaaaag aaatggaagc atcgtttcta
     1681 tgaacttaaa ggatgccttt gctagaagta tggaactgat cgacgtggcc gtggagaagg
     1741 ctggagagtc ggccaatatc aaggactccg tggatgataa ccacctgtct ccaagccggt
     1801 ggaagtgggc cagaaaggcg ctgtcggaaa caagctccaa caagtcttac gagaataagt
     1861 accaggaggt tagccaaaaa gactcccacg aacagctgaa caacacttct tcctccagcc
     1921 cacagcatct gagcgcccag aagctggaga tgctatacaa tgaaatcacc aagacacaga
     1981 ctcattccca cccgaaccca gactgccaag aacagccaga gaggccatct gcctatgagg
     2041 aggagataga aatggaagag gtggtctgcc cacaggagca gctggctgtg gcacagaccg
     2101 aggtcatcgt ggacatgaag agcacctcca gcattgacag cttcaccagc tgtgccactg
     2161 acttcacgga gactgagagg tcacccctgc caccaccctc tgcctctcac ttgcagatga
     2221 agttccccac cgacctccca ggaatggatg agcaccaaag agtcagggca cctccattcc
     2281 taacactaag cagagataag gggcctgctg ccagggaggc tgcactggat tatgccccaa
     2341 ttgacataac tgtgaacctc gatgctgggg cttcccatgg tcctttgcaa cctgacagtg
     2401 ccagcgacag ccccaagagc tcgctgaaag ggagcaaccc cctcaagtct agatccctaa
     2461 aagtgaactt tcaggaaaac agaggcagtg caccccagac cccacccagc acagccaggc
     2521 cactgccagt aaccacagct gactttccgc tcaccacccc ccagcacatg agtaccattc
     2581 ttctagaaga agccctcccc cagggacaga gaccttgccg ggggctgatg tttcagcaca
     2641 ctgtcaggga ccatccaaag gtctatcccc acgagttccc aagcaaaaac tgtttccttt
     2701 ctcttctaga gaaaggagga gcttcactga aatagacact ggagaagacg aagacttctt
     2761 ggacctccaa aggccaagac cagacaagca agcagatccc agccccaact gcttagcaga
     2821 taagcctgga gaggccagag accctttaag agaagagggc tgtgtgggtt cctcctctcc
     2881 ccagaacaca gaccacaact gtaggcaaga catttaccag gctgtgggtg aagtcaaaaa
     2941 ggacagtagt caagaagggt acaagatgga gaaccacttg tttgccccag aaattcattc
     3001 taacccagga gacacaggtt attgccccac tcgtgagacc agcatgtgac tagttataaa
     3061 agcaataaaa gaaaaagact catttcttaa aaatgcatta aaatgccgtg aactaaaata
     3121 tgagaaaccc cgccccctaa taccagtgca taaaatgtta tttttgcatg gcatgaacag
     3181 cttagtttaa ggattgttta aataaagagt tgagactgca ttttgtaaca aa
//