From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human insulin receptor gene, last exon
Date: 29 Dec 92 20:56:34 GMT
Distribution: bionet
Checksum: 55801 8

LOCUS       HUMINSRE     5165 bp ds-DNA             PRI       11-DEC-1992
DEFINITION  Human insulin receptor gene, last exon
ACCESSION   L07782
KEYWORDS    insulin receptor.
SOURCE      Homo sapiens (sub_species Caucasian) (library: Stratagene 946703)
            male DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Levy,J.R., Mooney,R.L. and Hug,V.
  TITLE     Sequence and characterization of the terminal exon of the human
            insulin receptor gene
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    1..5164
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="INSR"
     exon            <1..5164
                     /number=last
                     /gene="INSR"
     misc_feature    1..281
                     /note="overlaps with Ullrich's sequence bases 4897-5178
                     (Nature 313, 756-761 (1985))"
     polyA_signal    263..268
                     /gene="INSR"
     stem_loop       877..895
     polyA_signal    1605..1610
                     /gene="INSR"
     stem_loop       2428..2456
     polyA_signal    2591..2596
                     /gene="INSR"
     polyA_signal    4048..4053
                     /gene="INSR"
     polyA_signal    4060..4065
                     /gene="INSR"
BASE COUNT     1370 a   1062 c   1193 g   1531 t      9 others
ORIGIN      
        1 gagctcatcc ccctctctct ccttccttct tattgactgg gagactgtgc tctcgacaga
       61 ttcttcttgt gtcagaagtc tagcctcagg tttctaccct cccttcacat tggtggccaa
      121 gggaggagca tttcatttgg agtgattatg aatcttttca agaccaaacc aagctaggac
      181 attaaaaaaa aaaaaaagaa aaagaaagaa aaaacaaaat ggaaaaagga aaaaaaaaaa
      241 gaactgagat gacagagttt tgagaatata tttgtaccat atttaatttt taaagtctct
      301 ggtattagcc tcataagtta ttgactattc cccggggttg gcggggagtg gggtcatgag
      361 ttggtctgcc tgttgtgggg ccgggaaggg gagggagtca ggcacaagtg gcctctttgt
      421 ttggtctgaa aggcatccat ttctgggaat gaagccatgt tcgctgctaa cacttttgga
      481 tgtgtgaggc cagctgagtg tgtgagagac taggttttat ggatggctcg gttaggtacc
      541 agtctgctga agtctgtcga taagctggta gctacctagc tctgagcctg ccttcaagaa
      601 cacctgtgtt catcctctga ttctctgtgt gtacctcttg tggcgtttcc tctcccgggt
      661 gtgaacatcc taaccgttat tgtgcaaacc caagaacgtc agatcccaaa gcacaacaac
      721 ctggatggac tttgggaaca tctaagcaat ataagagaga ggtgcactga gagtacgtct
      781 tggtcccctc caccctgaga gcatctgacg gtcctcagta ctgaactccc ggaagctgct
      841 ctgagcccgg tgacctcatc tgggccaggt gtggtgcctg agctgaatgc tcaggtgctt
      901 acagtgttgc aatccctaag agagtagagt ctggaggaga aaccgtgaaa aaagacctta
      961 cacaccacca agaacttccg aatgggcgtg aatccaccgt ttcttctctt tgcaaaaaga
     1021 accaccacag ctgctcaaag aacacagtga actcatcact ttggttcatc aaaaaatcat
     1081 cgcccatgcg ttattcctga gtgcattttc ttacaacttt ttgactgctt ccttttcttc
     1141 ttctcttaag agttgtgggc ttaagaatgg gatagagtca taatggcaac ctccaagccc
     1201 tctcaattct tgattaagaa aacaggtaga catgaatccc aattgtctat tgctatctta
     1261 tttatatgat tcgggaaaat gcagcatgta aaaaatattg ctgaggagcc tcagtgattg
     1321 ggtacaagaa gcaagagtac agaaattatt tttgccaaat ttattttgta aatatgaggg
     1381 tctgtaccta aatttaaaaa aaaaaaacac gtagaactag gtatttgttc tcttcttagt
     1441 aaatttgtag tggttgtata ctacactagc tgcaattttc acatttttct aattcagaaa
     1501 ggtttttctt atattagggg aaaaagtatt tattttaata tataaaatca ctctgaaaat
     1561 cactctcata aaaaatggag cgcatgtaaa tttttatcaa agaaaaataa acaggtgaat
     1621 gggggatagt gattttcttt tttcagcaca gtctacctca gtgtattgtt aagatgtgat
     1681 tcaatcatgg acatctttga gatttcagaa ttctacctgg aaccggtctg aatcagggaa
     1741 cgtgtgtatc agactgattc gaatgccagg gaccagtaag aattttgagg gagggagttg
     1801 ggatggagaa ggtatggcct ttatgcgagc atagatcctt ttcttcctgg ctggtaatat
     1861 tcttctctga atttaatctt cctttaaaaa aaaatcctcc atctattgtc actatgttcc
     1921 ccaaacataa actaagttcc aggctgtcat gatgtatctg atatatgggg taacccagca
     1981 aggtgtgcct tcctttggtg agagatggct gccggggcaa agacgggctt tgattcagag
     2041 caagcattcc cacctgttcc atggaatccc cctgaagtga cgacaaaggt gccctgggct
     2101 ccctgatggt ttatgcccac tcctttcagg ctggtgatgc accttacaca caaacaccta
     2161 atgcaatgtc ttttaaattc tccaagtggg aatgggaagc atgtgaggga aattccaatc
     2221 caaaacccat taatgtgctg aacgcttttt tttttttttt tttttttttg caacaacacc
     2281 ttggacctcc gtgttggggt ttgactgacc tcaagctgat attattggac cttgtgcagc
     2341 tttgataacc catgtgagag tctaggcagg accagtgggg cccaaatctt gctgctcttg
     2401 tactttaggc actgcccttg cagactcacc tttctccacc tgccctggag aaaggtaggg
     2461 tgtgctgggc ctgccccttg caaatgggat tcaccagttt catttatttg actctactgc
     2521 cacagtgaaa agagcaaaca gctattgggt tgcaaacctc ctttgacatt aggaaatgtt
     2581 gactttgtaa caataaaact ttggtcctag aaagacacgg ttgtcctggg agtttgtagt
     2641 gttaagttgc aasaacaaca asaaaaagca acaaaaccag gcttaggata acacgttttt
     2701 gttgcttgtt cttaaacatg tctcactatg attaaaaacc cttttcatta atgtagtgaa
     2761 agccacacag gagttccttc ttccaggagg agaataccaa gcacatcact ttctctctgc
     2821 atcagtgatg tcaaatacgc atcagaaaat gttcaggttt taggagctgt cctaggtgct
     2881 gtttcatcat tggaagcagt gagaaagaga agcactgctg cttgtctgga tataggctga
     2941 ggatgattga gagaagctgt gggaactgac acaagggtct gcataggtca tcctgtgacc
     3001 ctggggacta tgttaccaac tgacagacag atctttcact gtatcctagc agggcaggta
     3061 gtccaccaag aaatgtgctt attggattgg gaggtgttta tttgtagtct gctgtaacac
     3121 gtgtgaaaga gcaggagcgt catcagcata tgacttgcgc tggtcatccg gtaaatggat
     3181 gtgctgtagt cccagtgcta atcatttctc tccttcacag tgggtggaag tttagggtta
     3241 aatgtccttt gaatgtcacc tggtgagtcc ttgacacctt aggctcttca gaaacaatgg
     3301 ttttgttgag gatggggaac agggaatgcc gattttatat acatggtaca cagagagggg
     3361 tgtcacttca gaaaatcttc cagcatgttc ttcagaatat taatttatat gcgaggtgag
     3421 gttgggaatg aaaagaacag gtcagcactt ttttttttcc tagaacatac aaaagaacat
     3481 ggtggacttt cagggagtgc aatggaaggt gaatatttcc ttaagggtcc ccgagaaatg
     3541 ggagtgaggg gaggggacac aatggctttt tgagccttac ttttaccttc tgatactagt
     3601 caaggtccag aaccagccac caccaaattt ctatctgggt gcgggccact gaaaatttct
     3661 ttgtttaaaa atccagatca caaatctggg gctcttggtc ccattggaga aggaaggaag
     3721 agcctcaaaa taagtgtgca cccatgcaca tattcaggaa cagcttgttt agtctttaca
     3781 ctttgcctga aagttgcttc tcctcgtccc tttgtgtgcc tgggtgcctc ggccctgtcg
     3841 gttggcaacg caggatcaaa tgtgctgcag cttttcgaga aaacaactca gaaacacaaa
     3901 accccccaac agctcaatta ttattttttc aatgttttcc tacaagagcc aagtagcacc
     3961 atgtacagaa gacgcctttt tttttggaat attgaaatcg ttctgcatgt aaaatatggg
     4021 ataatgacct gtttatatta aaattctgat taaattatct gagaatacgc ttgtttttgt
     4081 gtggtgtccc ggtaaggacc tgtcgtgtgg tcgggggatg tggctatgag ttgggctgtg
     4141 ttaaggaaaa cctcttggaa tatgtaggtg ccttttttta gaggagaaaa acacctagac
     4201 ttcttccaca catgaaaagg gaggttaaat agttgctacc agcagagttg atgactcgta
     4261 gggacatact tgtatggcca aactggtggt ttaaatattg cactatttcc ataccatttg
     4321 gtaagtaagc gcttccccaa gggctcccag acctccccat ggtccaacca ctaaagggtt
     4381 cactccgaga ataccaatga accttcaaga gcttgctcta ttctgacatg cggggaaact
     4441 catatgttaa gtatttcaat gtcatcctgg gagtggagac ctgtcccagg ttggtgacag
     4501 gtgagtgacc atgggttaga ccatgggatt gaaagccttt tgaatartct ttcttgagtg
     4561 gcttaaaaca gcaaatgttt atttattttc awttttttgt ttgtttgttt ttgtttttgt
     4621 tagtttrttt tttgaaatgg artctcaact ctgtcaacca ggctggagga magtggtgaa
     4681 atctcagctc actgcaacgc tgtctccggg ttcaagcggt tctcctgcct cagcctccca
     4741 agtagctggg attacgggcg tgtaccacca ttcccagcta attttgtatt tttagtttca
     4801 tcatgttggc cagactcgtc tcaaactcct gacctcaggt katccgccgc tcanctccaa
     4861 agtgctagat tacaggtgtg agcaccacac cagccttatt attatcatta tgatgattat
     4921 ttttgtattt taggtagaga cgggttttcg ccatgttgcc caggctggtc tcgaactact
     4981 gttctcaacg cgatctcgcc gcctcggcct cccaaagtgc tgggattgca ggcatgagcc
     5041 acggtgcctg gcctatttct tacagttcta tgtgttggtt gggtggttct tccgggaaca
     5101 gcctcactcc tgtgctgagg cctctgctgg gagagccagg attgcttgtc ttctaggagg
     5161 ttcgc
//