From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Leishmania tarentolae kinetoplast mitochondrial NADH dehydrogenase
Date: 29 Dec 92 19:49:54 GMT
Distribution: bionet
Checksum: 40757 5

LOCUS       LEIKPND7A    1200 bp ss-mRNA            ORG       09-DEC-1992
DEFINITION  Leishmania tarentolae kinetoplast mitochondrial NADH dehydrogenase
            subunit 7 (ND7) edited mRNA, complete cds.
ACCESSION   L07537
KEYWORDS    NADH dehydrogenase.
SOURCE      Kinetoplast Leishmania tarentolae (strain UC, chromosome
            Kinetoplast Leishmania tarentolae) promastigote mRNA.
  ORGANISM  Kinetoplast Leishmania tarentolae
            Eukaryota; Animalia; Protozoa; Sarcomastigophora; Mastigophora;
            Kinetoplastida; Trypanosomatina; Trypanosomatidae.
REFERENCE   1  (bases 1 to 1200)
  AUTHORS   De la Cruz,V.F., Neckelmann,N. and Simpson,L.
  TITLE     Sequences of six genes and several open reading frames in the
            kinetoplast maxicircle DNA of Leishmania tarentolae
  JOURNAL   J. Biol. Chem. 259, 15136-15147 (1984)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Shaw,J.M., Feagin,J.E., Stuart,K.D. and Simpson,L.
  TITLE     Editing of kinetoplastid mitochondrial mRNAs by uridine addition
            and deletion generates conserved amino acid sequences and AUG
            initiation codons
  JOURNAL   Cell 53, 401-411 (1988)
  STANDARD  full automatic
REFERENCE   3  (sites)
  AUTHORS   Shaw,J., Campbell,D. and Simpson,L.
  TITLE     Internal frameshifts within the mitochondrial genes for cytochrome
            oxidase subunit II and maxicircle unidentified reading frame 3 of
            Leishmania tarentolae are corrected by RNA editing: evidence for
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 86, 6220-6224 (1989)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    31..60
                     /note="edited domain II"
     misc_feature    233..241
                     /note="edited domain I"
     CDS             5..1198
                     /gene="ND7"
                     /note="Was previously ORF3/ORF4 and then MURF3. This
                     protein is similar to ORF392 from Marcantia chloroplast
                     and therefore homologous to the iron sulfur 46 kd
                     component of NADH dehydrogenase in complex I of the
                     electron transport chain"
                     /product="NADH dehydrogenase subunit 7"
                     /codon_start=1
                     /translation="ILFSRLHDNYILYLLIVFLHLYRFTFGPQHPAAHGVLCCLLYLS
                     GEFMTYMDVIIGYLHRGTEKLCEYKTVEQCLPYFDRLDYVSVVCNEHLLSLCFEYMLR
                     CCLAMRCAFMRLLMCEFTRCFNGLLCCSCMVMDMGSLSPMLWSFEERDKLMTFFDLCC
                     GCRMHLAFMCLLGLLDDFVFGFMDFLLMLCISCLFVLDLYDLLFVGNRLLYLRLRGLA
                     FFDMFDLCFNSISGCLSRSLGMVWDVRLYSCYELYFMLVFDYCFCYLGDAFDRLFLRL
                     FDMRMSILLCKQCFFVGFFVFGFVCLFDYMYVDVTMETMISLFYSLWCCILPGCSFAN
                     VEHPKGEYSLFLCFLYGFISRLRIRCADFVHICLLDVMMRGFMLHDLVAVIGNVDVVF
                     GSVDR"
BASE COUNT      295 a    115 c    235 g    555 t
ORIGIN      
        1 ttaaatttta tttagccgac tacacgataa ttatatttta tatttattaa ttgttttttt
       61 acacttgtat agatttactt tcggacccca gcatccagca gcccatggcg tattatgttg
      121 tttattatat ctttctggag aatttataac gtatatagat gtaattattg ggtatttaca
      181 tcgaggtaca gaaaagttat gtgaatataa aacagtagag cagtgtttac cgtattttga
      241 tagactggat tatgtaagtg tagtttgtaa tgaacattta ttatctttat gttttgaata
      301 tatgttaaga tgctgtctag caatacgttg tgcatttatg cgtctattaa tgtgtgaatt
      361 tacgcgatgt tttaatgggc ttttatgttg ttcttgcatg gttatggata taggttcatt
      421 atcaccaatg ttgtgatcat ttgaagagcg tgacaagtta atgacttttt ttgatttatg
      481 ttgcggttgc agaatgcatt tagcgtttat gtgtttatta ggtctattag atgattttgt
      541 tttcggattt atagattttt tgttaatgtt atgtatttca tgtttatttg ttttagattt
      601 gtatgatttg ctttttgtag gtaatagact tttgtatttg cgtttacgag gccttgcatt
      661 ttttgatata tttgacttat gctttaatag tattagtggt tgtttatcta gatctttagg
      721 tatggtatga gatgtaagat tatatagttg ctatgaatta tactttatgt tggtttttga
      781 ttattgtttt tgttatttag gtgatgcatt cgaccgtctt tttttacgtt tatttgatat
      841 gcgaatgagt atccttttat gcaagcagtg tttttttgta ggtttttttg tttttggctt
      901 tgtatgttta tttgattata tgtatgtgga tgttactata gaaaccataa ttagtttatt
      961 ttatagttta tgatgttgta ttttaccagg ctgttctttt gcaaatgttg aacatccaaa
     1021 aggtgaatat agcctatttt tatgcttttt atatggattt atctcacgtt tacgtattcg
     1081 ttgtgcagat tttgtacata tttgtttatt agatgtaatg atgcgtggtt tcatgttaca
     1141 tgacttagta gcagttatcg gaaatgttga tgttgttttt ggttctgttg acaggtaaat
//