From: eclark@gauss.math.usf.edu. (Edwin Clark)
Newsgroups: sci.med
Subject: Re: fibromyalgia questions
Date: 5 Jan 93 02:18:30 GMT
Organization: Univ. of South Florida, Math Department

In article <1hqp68INNgpe@gap.caltech.edu> rap@wag.caltech.edu (Rick A. Pinson) writes:
>
>Hello,
>	My mother has been diagnosed as having Fibromyalgia, some
>	people say it's the same thing as chronic fatigue syndrome
>	but I'm not sure.  I'm looking for information about new
>	treatments or any ongoing research.  So far, nothing has
>	helped her much, and any info would be appreciated.
>
>Rick Pinson


Here are a few abstracts I happened to have. If you can search
the medline data base --- try a nearby med school library --you
can find lots more information I'm sure. --Edwin Clark

1/L/15
07146646   90053646
  Treatment of fibrositis with fluoxetine hydrochloride (Prozac).
  Geller SA
  Howard County General Hospital Columbia, Maryland 21044.
  Am J Med (UNITED STATES)   Nov 1989,  87 (5) p594-5,  ISSN 0002-9343
Journal Code: 3JU
  Languages: ENGLISH
  JOURNAL ANNOUNCEMENT: 9002
  Subfile:   AIM; INDEX MEDICUS
  Tags: Case Report; Female; Human
  Descriptors:  *Fibromyalgia--Drug  Therapy--DT;  *Fluoxetine--Therapeutic
Use--TU; Adult
  CAS Registry No.: 54910-89-3   (Fluoxeti


/L/6
  1613221   28-03575
  Fluoxetine and fibromyalgia
  Finestone, D. H.; Ober, S. K.
  East Carolina Univ. Sch. of Med., Greenville, NC, USA
  JAMA 264:2869-2870 (Dec 12) 1990
  Coden: JAMAAP
  Languages: English
  DOC TYPE: Letters
  (5 References)
  The  successful therapy of fibromyalgia in 2 female patients, aged 41 and
49  yr,  who were treated with fluoxetine hydrochloride (Prozac), 20 mg/day
for 3 months and one month, respectively, is reported.
  One   patient   required   additional  therapy  with  50  mg/day  doxepin
hydrochloride   for   nighttime   nervousness   attributed   to  fluoxetine
hydrochloride.
  It  was  suggested  that  the  mechanism  by  which  fluoxetine  acts  in
fibromyalgia  may  be  due to augmentation of serotonin, a neurotransmitter
involved  in  the regulation of mood, restorative sleep, and sensitivity to
pain.
  Peggy L. Ruppel
  Trade Names: Prozac
  Descriptors:    Fluoxetine    hydrochloride   -   fibromyalgia;   Doxepin
hydrochloride   -   anxiety;   Analgesics  and  antipyretics  -  fluoxetine
hydrochloride; Anxiolytics, sedatives and hypnotics - doxepin hydrochloride
;  Toxicity  -  fluoxetine  hydrochloride; Pain - fluoxetine hydrochloride;
Mechanism of action - fluoxetine hydrochloride
  CAS Registry No: 56296-78-7; 1229-29-4
  Section Headings: Drug Evaluations-(06); Toxicity-(04)

 1/L/11
06454380   88099380
  Palindromic rheumatism. A clinical survey of sixty patients.
  Hannonen P; Mottonen T; Oka M
  Department of Medicine, Central Hospital, Jyvaskyla, Finland.
  Scand J Rheumatol   1987,  16 (6) p413-20,  ISSN 0300-9742
Journal Code: UD1
  Languages: ENGLISH
  JOURNAL ANNOUNCEMENT: 8804
  Subfile:   INDEX MEDICUS
  Sixty  patients  with  palindromic rheumatism (PR) with a total follow-up
time  of  598  years  and  295 years prospectively are presented. The study
shows that PR is not a rare condition, but the syndrome is often ignored or
misdiagnosed  by  the  physician.  Most  cases  of PR appear to evolve into
chronic arthritis. PR may precede other kinds of systemic diseases, such as
SLE,  Wegener's granulomatosis, and multiple myeloma. The presence of PR in
patients  with  fibromyalgia  is reported in this paper. Gold appears to be
the  best  drug  for  the treatment of PR. Cases of fibromyalgia and PR are
treated  successfully  with  antimalarial  drugs.  Our  proposed diagnostic
criteria  for  PR are as follows: 1) recurrent attacks of sudden-onset mono
or  polyarthritis  or  of periarticular tissue inflammation, lasting from a
few  hours  to  one  week;  2)  verification  of  at  least one attack by a
physician;  3)  subsequent  attacks  in at least three different joints; 4)
exclusion of other forms of arthritides.
  Tags: Female; Human; Male
  Descriptors:  *Arthritis--Epidemiology--EP;  *Periarthritis--Epidemiology
--EP;  Adult;  Arthritis--Classification--CL;  Arthritis--Drug Therapy--DT;
Follow-Up Studies; Gold--Therapeutic Use--TU; Periarthritis--Classification
--CL;  Periarthritis--Drug Therapy--DT; Prospective Studies; Recurrence
  CAS Registry No.: 7440-57-5   (Gold)


-----end of abstracts-----

PS. If you look around you may also be able to find a support group
for people with fibromyalgia. BTW I'm not pushing any of the above 
medications, these are just abstracts that I found when searching for
articles on prozac and palindromic rheumatism.



--
W. Edwin Clark
Mathematics Department
University of South Florida
Tampa, FL 33620-5700
Newsgroups: sci.med