From: calendar@ALMADEN.IBM.COM (IBM Almaden Research Center Calendar)
Newsgroups: ba.seminars
Subject: IBM ARC seminars 29 SEP - 3 OCT 92
Date: 28 Sep 92 15:16:22 GMT


                     IBM Almaden Research Center
                           650 Harry Road
                       San Jose, CA 95120-6099

                              CALENDAR
                    September 28 - October 2, 1992



09/30 - PROGRESS IN RESEARCH ON FUNCTIONAL MATERIALS AND DEVICES
Prof. Z. Shichang, Shanghai Inst.of Metallurgy, Acad.Sinica, Shanghai,
China

Phys. Sci. Sem.    Wednesday, September 30    10:30 a.m.    Room: J2-609

High performance functional materials are of current special interest in
China.  Examples, which will be reported in this paper, include compound
semiconductors, sensing materials, diamond films, magneto-optical
materials, high Tc superconductors and surface modification by ion
implantation.  For compound semiconductor materials, main efforts of
Shanghai Institute of Metallurgy (SIM) are concentrated on the growth of
bulk single crystals, such as GaAs, InP, GaSb, etc., and preparation of
epitaxial layer with MBE and MOCVD techniques.  In recent years solid
state transducers and biological sensors are in rapid progress in SIM.
Since diamond is a potential semiconductor for high power, high
temperature, and high frequency devices, SIM is working on CVD diamond
films for semiconductor applications.  In response to the demand for
high density, large capacity recording media at present, to speed up the
development and commercialization of erasable magneto-optical disk with
large capacity, the Chinese Academy of Sciences operates a Joint
Laboratory of Optical Disk at SIM.  SIM has also developed bulk and thin
film high Tc superconductor materials, last year bulk materials in Jc
over 105A/cm2 at 77K, 8.8T.  Ion beam technologies for surface
modification of materials have been developed in SIM to synthesize new
electronic materials and modify the properties of surface layers.
Host: J. Baglin


10/01 - SCANNING FORCE MICROSCOPY ON LIVING VIRUS-INFECTED CELLS
D. P. E. Smith, IBM Physics Group, Schellingstrasse 4, Munich, Germany

Phys. Sci. Sem.    Thursday, October 1    12:00 p.m.    Room: J2-601

Using scanning force microscopy it has been possible to follow the
process of viral infection on a single living cell.  Living
monkey-kidney cells were imaged under normal growth conditions with a
resolution of 10 nm.  Upon adding a suspension of pox virus, pronounced
changes were observed in the cell membrane.  Two hours after infection,
protrusions appeared which we interpret to be related to viral
metabolism.  After 20 hours, a different type of event occurred which we
interpret as the exocytosis of progeny viruses.
Host:  S. Chiang


10/02 - WHY SHOULD WE SEQUENCE THE WHOLE HUMAN GENOME?
Prof. C. Wills, Department of Biology, UC San Diego

Phys. Sci. Colloq.     Friday, October 2     10:30 a.m.     Room: Aud. A

The goal of the Human Genome Project is to sequence our entire genome,
all the three billion bases of human DNA, by the year 2005.  But less
than ten percent of our genome is made up of genes, stretches of DNA
that actually code for proteins.  Should we concentrate on the genes and
forget about the rest of the DNA?  No, because more and more evidence is
emerging that other parts of our DNA have important functions, ranging
from the maintenance of the structure and integrity of chromosomes to
the regulation of genes during development.  If we are to understand
important cellular processes such as aging and devastating diseases such
as cancer, mental illness and chromosome aberrations, we must understand
the whole genome, not just the genes that are embedded in the rest of
the DNA like tempting raisins in a pudding.  But the goal of the project
will never be met unless ways are found to sequence DNA more quickly and
accurately.  I will suggest ways in which this can be done, by
hybridizing biochemistry and molecular biology with new technologies
such as the scanning tunneling and atomic force microscopes.  Technology
to sequence single molecules will be essential to the success of the
project, and this will require cooperation among physicists, engineers
and biologists.
Host: M.  Philpott

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For further information on individual talks, please contact the host
listed above.

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Center (ARC) is located adjacent to Santa Teresa County Park, between
Almaden Expressway and U.S. 101, about 10 miles south of Interstate
280.  From U.S. 101, exit at Bernal Road, and follow Bernal Road west
past Santa Teresa Blvd. into the hills (ignoring the left turn for
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entrance (about a quarter of a mile later) and go up the hill.  For
more detailed directions, please phone the ARC receptionist at (408)
927-1080.

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