From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human Bullous pemphigoid autoantigen BP180 gene, 3' end.
Date: 21 Dec 92 20:18:57 GMT
Distribution: bionet
Checksum: 20248 10

LOCUS       HUMBP180AA   4669 bp ss-mRNA            PRI       17-NOV-1992
DEFINITION  Human Bullous pemphigoid autoantigen BP180 gene, 3' end.
ACCESSION   M91669
KEYWORDS    BP180 autoantigen; autoantigen.
SOURCE      Homo sapiens (library: lambda gt11, Clonetech Lab., Inc.,) neonatal
            foreskin cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4669)
  AUTHORS   Giudice,G.J., Emery,D.J. and Diaz,L.A.
  TITLE     Cloning and primary structural analysis of the Bullous pemphigoid
            autoantigen, BP180
  JOURNAL   J. Invest. Dermatol. 99, 243-250 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             <1..4599
                     /standard_name="BP180 autoantigen"
                     /note="(1504..1572) transmembrane domain; (1804..4550)
                     collagenous domain"
                     /gene="BP180"
                     /product="autoantigen"
                     /codon_start=1
                     /translation="PLQISRRKHQEKKERGGFIQSCFQFLQNLKPGGYGMDVTKKNKR
                     DGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHGSSGYINS
                     TGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPEYPRKE
                     FASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSSNTL
                     PIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTTQ
                     SSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTT
                     TTSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKE
                     MELLIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVST
                     KGKTTTADIHSYSSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLL
                     TWLLLLGLLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAA
                     GADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGT
                     PGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERG
                     AAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGP
                     PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMP
                     GIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPG
                     PPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPR
                     GPPGEGLPGPPGPPGSFLSNSETFLFGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGF
                     STSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPP
                     GPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGE
                     TFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPP
                     GPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLR
                     GSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRG
                     PPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTD
                     ASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGP
                     GGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPP
                     GQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAG
                     PPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP"
BASE COUNT     1072 a   1402 c   1350 g    845 t
ORIGIN      
        1 ccgctgcaaa tttctagaag aaaacatcag gagaagaaag agagaggggg atttattcaa
       61 agttgtttcc aattccttca aaacctcaaa ccaggtggct atggtatgga tgtaaccaag
      121 aaaaacaaac gagatggaac tgaagtcact gagagaattg tcactgaaac agtaaccaca
      181 agacttacat ccttaccacc aaaaggcggg accagcaatg gctatgctaa aacagcctct
      241 cttggtggag ggagccggct ggagaaacaa agcctgactc atggcagcag cggctacata
      301 aactcaactg gaagcacacg aggccatgcc tccacctcta gttacaggag ggctcactca
      361 cctgcctcca ctctgcccaa ctccccaggc tcaacctttg aaaggaaaac tcacgttacc
      421 cgccatgcgt atgaagggag ctccagtggc aactcttctc cggagtaccc tcggaaggaa
      481 tttgcatctt cttcaaccag aggacggagt caaacacgag agagtgaaat tcgagttcga
      541 ctgcagagtg cgtccccatc cacccgatgg acagaattgg atgatgttaa gcgtttgctc
      601 aaggggagtc gatcggcaag tgtgagcccc acccggaatt cctccaacac actccccatc
      661 cccaagaaag gcactgtgga gaccaaaatt gtgacagcga gctcccagtc ggtgtcaggc
      721 acctacgatg caacgatcct ggatgccaac cttccctccc atgtgtggtc ctccaccctg
      781 cccgcggggt cctccatggg gacctatcac aacaacatga caacccagag ctcatccctc
      841 ctcaacacca atgcctactc tgcgggatca gtcttcggag ttccaaacaa catggcgtcc
      901 tgctcaccca ctttgcaccc tggactcagc acatcctcct cagtgtttgg catgcagaac
      961 aatctggccc ccagcttgac caccctgtcc catggcacca ccaccacttc cacagcatat
     1021 ggggtgaaga aaaacatgcc ccagagtcct gcggctgtga acactggcgt ttccacctcc
     1081 gccgcctgca ccacaagtgt gcagagcgat gaccttttgc acaaggactg caagttcctg
     1141 atcctagaga aagacaacac acctgctaag aaggagatgg agctgctcat catgaccaag
     1201 gacagcggga aggtctttac agcctcccct gccagcatcg ctgcaacttc tttttcagaa
     1261 gacaccctaa aaaaagaaaa gcaagctgcc tacaatgctg actcaggcct aaaagccgaa
     1321 gctaatggag acctgaagac tgtgtccaca aagggcaaga ccaccactgc agatatccac
     1381 agctacagca gcagtggtgg tggtggcagt ggaggaggtg gcggtgttgg tggcgctggc
     1441 ggcggccctt ggggaccagc gccagcctgg tgcccctgcg gctcctgctg cagctggtgg
     1501 aagtggctgc tgggcctgct gctcacctgg ctgctactcc tggggctgct cttcggcctc
     1561 attgctctgg cggaggaggt gaggaagctg aaggcgcgtg tggatgagct ggagaggatc
     1621 aggaggagca tactgcccta tggggacagc atggatagaa tagaaaagga ccgcctccag
     1681 ggcatggcac ccgcggcggg agcagacctg gacaaaattg ggctgcacag tgacagccag
     1741 gaggagctct ggatgttcgt gaggaagaag ctaatgatgg aacaggaaaa tggaaatctc
     1801 cgaggaagcc ctggccctaa aggtgacatg ggaagtccag gccctaaagg agatcgaggg
     1861 ttccctggga ctccaggtat ccctgggccc ttgggccacc caggtccaca aggaccaaag
     1921 ggtcaaaaag gcagcgtggg agatcctggc atggaaggcc ccatgggcca gagagggcga
     1981 gaaggcccca tgggacctcg tggtgaggca gggcctcctg gatctggaga gaaaggggaa
     2041 agaggggctg ctggtgaacc aggtcctcat ggcccacctg gtgtcccagg ttctgtgggt
     2101 cccaaaggtt ccagcggctc tcctggccca cagggccctc caggtcctgt aggtctccaa
     2161 gggctccgag gtgaagtagg acttcctggt gtcaaaggtg acaaaggacc aatgggacca
     2221 ccaggaccca aaggtgacca gggtgagaaa ggacctcgag gcctcacagg cgagcctggc
     2281 atgagaggtt tgcctggtgc tgttggtgag cccggggcta aaggagcaat gggtcctgct
     2341 ggcccagacg gacaccaagg cccaagaggt gaacaaggtc ttactgggat gcctggaatc
     2401 cgtggcccac caggaccttc tggagaccca ggaaagccag gtctcacagg accccaggga
     2461 cctcagggac ttcccggtac ccctggccga ccaggaataa aaggtgaacc aggagctcca
     2521 ggcaagatcg tgacttcgga ggggtcatcg atgctcactg tcccaggccc cccaggacct
     2581 cctggagcca tgggaccccc aggacctcca ggtgccccag gccctgccgg cccagctggt
     2641 ctcccaggac atcaagaagt tcttaattta caaggtcccc caggcccacc cggcccacgt
     2701 gggccaccag ggccttccat tccaggccca ccaggacccc gaggcccacc aggggagggt
     2761 ttgccaggcc caccaggccc accaggatcg ttcctgtcca actcagaaac cttcctcttc
     2821 ggccccccag gcccacctgg ccccccaggt cccaagggag accaaggtcc cccaggcccc
     2881 agaggacacc aaggcgagca aggcctccca ggtttctcaa cctcagggtc cagttctttc
     2941 ggactcaacc ttcagggacc accaggccca cctggccccc agggaccaaa aggtgacaaa
     3001 ggtgatccgg gtgttccagg ggctcttggc attcctagtg gtccttctga agggggatca
     3061 tcaagtacca tgtacgtgtc aggcccgcca gggccccctg ggccccctgg gcctccgggc
     3121 tctatcagca gctctggcca ggagattcag cagtacatct ctgagtacat gcagagtgac
     3181 agtattagat cttacctatc cggagttcag ggtcccccag gcccacctgg tcccccagga
     3241 cctgtcacca ccatcacagg cgagactttc gactactcag agctggcaag ccacgttgtg
     3301 agctacttac ggacttcggg gtacggtgtc agcttgttct cgtcctccat ctcttctgaa
     3361 gacatcctgg ctgtgctgca gcgggatgac gtgcgtcagt acctacgtca gtacttgatg
     3421 ggccctcggg gtccgccagg gccaccagga gccagtggag atgggtccct cctgtctttg
     3481 gactatgcag agctgagtag tcgcattctc agctacatgt cgagttctgg gatcagcatt
     3541 gggcttcctg gtcccccggg gccccctggc ttgccgggaa cctcctatga ggagctcctc
     3601 tccttgctgc gagggtctga attcagaggc atcgttggac ccccaggtcc cccgggtcca
     3661 ccagggatcc caggcaatgt gtggtccagc atcagcgtgg aggacctctc gtcttactta
     3721 catactgccg gcttgtcatt catcccaggc cctccaggac ctcctggtcc cccagggcct
     3781 cgagggcccc cgggtgtctc aggagccctg gcaacctatg cagctgaaaa cagcgacagc
     3841 ttccggagcg agctgatcag ctacctcaca agtcctgatg tgcgcagctt cattgttggc
     3901 cccccaggcc ctcctgggcc gcagggaccc cctggggaca gccgcctcct gtccacggat
     3961 gcctcccaca gtcggggtag cagctcctcc tcacacagct catctgtcag gcggggcagc
     4021 tcctacagct cttccatgag cacaggagga ggtggtgcag gctccctggg tgcaggcggt
     4081 gcctttggtg aagctgcagg agacaggggt ccctatggca ctgacatcgg cccaggcgga
     4141 ggctatgggg cagcagcaga aggcggcatg tatgctggca atggcggact attgggagct
     4201 gactttgctg gagatctgga ttacaatgag ctggctgtga gggtgtcaga gagcatgcag
     4261 cgtcagggcc tactgcaagg gatggcctac actgtccagg gcccaccagg ccagcctggg
     4321 ccacaggggc cacccggcat cagcaaggtc ttctctgcct acagcaacgt gactgcggac
     4381 ctcatggact tcttccaaac ttatggagcc attcaaggac cccctgggca aaaaggagag
     4441 atgggcactc caggacccaa aggtgacagg ggccctgctg ggccaccagg tcatcctggg
     4501 ccacctggcc ctcgaggaca caagggagaa aaaggagaca aaggtgacca agtctatgct
     4561 gggcggagaa ggagaagaag tattgctgtc aagccgtgag ctagccatgg caggacagct
     4621 cctggaccag gtctcataat gcatgtggca cttaggtcca aggtctcca
//