HDTenEightyP/NetNews huggingface dataset:
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human HepG2 3'-directed MboI cDNA, clone kmb01
Date: 29 Dec 92 00:42:06 GMT
Distribution: bionet
Checksum: 48873 2

LOCUS       HUM00KMB01    350 bp ds-DNA             PRI       03-DEC-1992
DEFINITION  Human HepG2 3'-directed MboI cDNA, clone kmb01
ACCESSION   D11907
KEYWORDS    expressed sequence tag.
SOURCE      Homo sapiens Male Liver cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 350)
  AUTHORS   Okubo,K., Hori,N., Matoba,R., Niiyama,T., Fukushima,A., Kojima,Y.
            and Matsubara,K.
  TITLE     Large scale cDNA sequencing for analysis of quantitative aspects of
            gene expression
  JOURNAL   Nature Genet. 2, 173-179 (1992)
  STANDARD  full automatic
BASE COUNT       93 a     75 c     84 g     98 t
ORIGIN      
        1 gatcctctag agtcggtccc ccgcctgtac ccgccggccc tcgtaggggg agccccatcc
       61 tactcctggg gcctggccac accagctggg gctctgggag ataccctcgg cgcggcgggg
      121 ctccaattgg ccatttaagt ttagtagtaa aagactggtt aatgataaca atgcatcgta
      181 aaaccttcag aaggaaagga gaatgttttg tggaccactt tggttttctt ttttgcgtgt
      241 ggcagtttta agttattagt ttttaaaatc agtacttttt aatggaaaca acttgaccaa
      301 aaatttgtca cagaattttg agacccatta aaaaagttta aatggagaaa
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human immunodeficiency virus type 1, sample 6002, clone MA02 from
Date: 29 Dec 92 00:28:46 GMT
Distribution: bionet
Checksum: 39550 2

LOCUS       HIVH6002M2    341 bp ss-DNA             VRL       03-DEC-1992
DEFINITION  Human immunodeficiency virus type 1, sample 6002, clone MA02 from
            Haiti, env V3 region.
ACCESSION   L07197
KEYWORDS    .
SOURCE      Human immunodeficiency virus type 1 (HIV-1), sample 6002MA02 from
            Haiti (PCR amplification and cloning).
  ORGANISM  Human immunodeficiency virus type 2
            Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
            Retroviridae; Lentivirinae.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Ou,C.-. and Kalish,M.
  TITLE     (no title given)
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     Kindly provided prior to publication in computer-readable form by
            CDC (Centers for Disease Control), Public Health Service, Dept. of
            Health and Human Services, Atlanta, GA  30333.  Sequence H6002MA03
            is identical to <HIVH6002M2> except that it substitutes G for A at
            position 170, A for G at 193, G for A at 260, and C for T at 311.
FEATURES             Location/Qualifiers
     CDS             <1..>341
                     /product="envelope polyprotein"
                     /codon_start=1
                     /translation="EEIVIRSENFTDNAKTIIVQLKEPVQINCTRPNNNTRKSIHIGP
                     GRAFYTTGDIIGDIRQAHCNVSRTKWNNTLRQVVDKLKEQFKNKTIVFNHSSGGDPEI
                     VMYSFNCGGEF"
BASE COUNT      147 a     46 c     66 g     82 t
ORIGIN      
        1 gaagagatag taattaggtc tgaaaatttc acggacaatg ctaaaaccat aatagtacag
       61 ctgaaggaac ctgtacaaat taattgtaca agacccaaca ataatacaag aaaaagtata
      121 catataggac cagggagagc attttataca acaggagaca taataggaga tataagacaa
      181 gcacattgta acgttagtag aacaaaatgg aataacactt taagacaggt agttgacaaa
      241 ttaaaagaac aatttaagaa taaaacaata gtctttaatc actcctcagg aggggaccca
      301 gaaattgtaa tgtacagttt taattgtgga ggggaatttt t
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human HepG2 3'-directed MboI cDNA, clone a-22
Date: 21 Dec 92 20:18:20 GMT
Distribution: bionet
Checksum: 03506 2

LOCUS       HUM000AA22    480 bp ds-DNA             PRI       18-NOV-1992
DEFINITION  Human HepG2 3'-directed MboI cDNA, clone a-22
ACCESSION   D11490
KEYWORDS    expressed sequence tag.
SOURCE      Homo sapiens Male Liver cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Okubo,K., Hori,N., Matoba,R., Niiyama,T., Fukushima,A., Kojima,Y.
            and Matsubara,K.
  TITLE     Large scale cDNA sequencing for analysis of quantitative aspects of
            gene expression
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
BASE COUNT      106 a    114 c    121 g     77 t     62 others
ORIGIN      
        1 gatcnggagg aggngaaggc caangtgcag ccctaccnng acgnctnnca gaanaagtng
       61 cangaggaga tcgagctcta ccnccagaag gtggagccgc tgcgcgcaga gctccangag
      121 cngcgcgcgn cagaagctgc acgagctaca ngagaagctn ancccactng ncgagggaga
      181 tgcgcgaccn tnnagnaccc atntngacgc gctgcgcacg atctggcccc ctanagcnac
      241 gnntgngcan catnctgncg ngtncttgag gtctcaagga gaactgcagc cncagactgn
      301 cgagtaccac tgcaangtca ccnagcatct nagcanggtc agngacaagg caagccgggn
      361 tngacagcgt cgtnaggnct catccnntnn tggcatctta aggcagtttt gaagtctttn
      421 acnttgattt gaggtaacac tatanggctt nncgccnntt nntntaaata antttcaatt
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human (clone R6B8H) Ig rearranged H-chain mRNA V-region, 5' end.
Date: 29 Dec 92 19:57:42 GMT
Distribution: bionet
Checksum: 43324 3

LOCUS       HUMIGHRD      426 bp ss-mRNA            PRI       10-DEC-1992
DEFINITION  Human (clone R6B8H) Ig rearranged H-chain mRNA V-region, 5' end.
ACCESSION   M99601
KEYWORDS    complementarity determining region; immunoglobulin heavy chain;
            processed gene; variable region.
SOURCE      Homo sapiens female adult blood cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Weng,N.-P., Yu-Lee,L.Y., Sanz,I., Patten,B.M. and Marcus,D.M.
  TITLE     Structure and specificities of anti-ganglioside autoantibodies
            associated with motor neuropathies
  JOURNAL   J. Immunol. 149, 2518-2529 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     1..57
                     /gene="IGHV@"
                     /codon_start=1
     misc_feature    148..168
                     /standard_name="CDR-1"
                     /gene="IGHV@"
     misc_feature    211..258
                     /standard_name="CDR-2"
                     /gene="IGHV@"
     misc_feature    352..393
                     /standard_name="CDR-3"
                     /gene="IGHV@"
     CDS             1..>426
                     /gene="IGHV@"
                     /product="immunoglobulin heavy chain"
                     /codon_start=1
                     /translation="MKHLWFFLLLVAAPRWVLSQVQLQESGPGLVKPSQTLSLTCTVS
                     GGSISTGGYYWSWIRQHPGKGLEWIGYIFYSGSTYYNPSLKSRVSISVDTSNQFSLKL
                     SSVTAADTAVYFCARGEWGVRGIQPHFDFWGQGTLVTVSS"
BASE COUNT       81 a    123 c    125 g     97 t
ORIGIN      
        1 atgaaacacc tgtggttctt cctcctgctg gtggcagctc ccagatgggt cctgtcccag
       61 gtgcagctgc aggagtcggg cccaggactg gtgaagcctt cacagaccct gtccctcacc
      121 tgcactgtct ctggtggctc catcagcact ggtggttatt actggagctg gatccgccag
      181 cacccaggga agggcctgga gtggattggg tacatctttt acagtgggag cacctactac
      241 aacccgtccc tcaagagtcg agttagcata tcagtagaca cgtctaacca gttctccctg
      301 aagctgagct ctgtgactgc cgcggacacg gccgtgtatt tctgtgcgag aggcgagtgg
      361 ggggttcggg gaatacagcc acactttgac ttctggggcc agggaaccct ggtcaccgtc
      421 tcctca
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: X.laevis U3B gene for U3 small nuclear RNA
Date: 21 Dec 92 20:37:11 GMT
Distribution: bionet
Checksum: 63124 3

LOCUS       XELU3BG      1231 bp ds-DNA             VRT       18-NOV-1992
DEFINITION  X.laevis U3B gene for U3 small nuclear RNA
ACCESSION   Z12612
KEYWORDS    U3 small nuclear RNA; small nuclear RNA.
SOURCE      Xenopus laevis DNA.
  ORGANISM  Xenopus laevis
            Eukaryota; Animalia; Chordata; Vertebrata; Amphibia; Lissamphibia;
            Anura; Archeobatrachia; Pipoidea; Pipidae; Xenopodinae.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Gerbi,S.A.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1231)
  AUTHORS   Genexpress,X.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 1231)
  AUTHORS   Savino,R., Hitti,Y.S. and Gerbi,S.A.
  TITLE     Genes for Xenopus laevis U3 small nuclear RNA
  JOURNAL   Nucleic Acids Res. 20, 5435-5442 (1992)
  STANDARD  full automatic
COMMENT     *source: clone=pXlU3A;
               From EMBL    entry XLU3BG;  dated 13-OCT-1992.
FEATURES             Location/Qualifiers
     snRNA           721..938
                     /standard_name="U3"
BASE COUNT      330 a    251 c    323 g    327 t
ORIGIN      
        1 cactgtgtaa actcagtgaa ttttttgggt gtgaggtgca atcaggtgat cattaagggc
       61 ctatcagctt ctgtcacgtg cccaggagac ctgcatagca agaatctttg gacccacctt
      121 cagcacaagg ctagggtggc cactatgtcc tctacccccc cccaggagaa aacgcttccc
      181 acaatcctct gcatgtcagg ctagtggggt ccctttgccc cgatcctcaa gccacaagga
      241 acataaggga ggggaagtct ttagacccct gaaaggaccc aataaaaggg gcttcacctc
      301 tgaacatgtt cctgtgtctc caacgggtcc catgtgggtg ctcccccaat agttacacca
      361 ctggtcacat gtcaaataag agccgcaagg ctttaggtca catgtcccaa acagccaatc
      421 ccctgaccaa attcagaagt gactgcgaca gatgtttcct cctgattgat tggtgggcgg
      481 gtcaggtggg tgtgacacat gcaaatgagc agctggggga aactgaacac tacaattctg
      541 cactaatcat tgtgtttctg tagctttaca tgttgtagta agttagtaat gttgttgtag
      601 agcaataaat gtgggggtgc agtctctaat ggggggctga gtgtaactat ggatttatgt
      661 cgccttgaga gtaaagaggg tccgtccctg ggtggtgggt gcttgtttca atgtatcagt
      721 aagactatac tttcagggat catttctata ggttgtatct ggtgaaatgt gctcgaaagt
      781 gtctgaactc acaaaccacg aggaagagcg tcagtgttct ctcctgagcg tgaagtgagc
      841 tcacagtgct gcttcattgt ggctgctgtt tgctattgat gaacgttctg ctccccttaa
      901 tattggggag atggagggag agatcacagg ctgagtggtt ttcttataca aaagtagaaa
      961 agcagaataa acaaatatct tcatttatga atctctgtgg attctgaaag aattaccaat
     1021 aaaacaacag gattcttttt actctaccac aatccaaaga tgtagaggga agttaattgg
     1081 ttcctgaatg aactgctcat tgaagatgag agtgatggga atattaaagg gaccttagat
     1141 tgcaagctca ctggggcaag gctggatggg aatgtgatag ggtcaataga ctgtaagctc
     1201 actgggcaga gagtgatggg gaatgtgatc g
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Lamna nasus mitochondrial cytochrome b gene, complete cds.
Date: 31 Dec 92 01:37:55 GMT
Distribution: bionet
Checksum: 37317 3

LOCUS       LMNMTCYTBA   1146 bp ds-DNA             ORG       17-DEC-1992
DEFINITION  Lamna nasus mitochondrial cytochrome b gene, complete cds.
ACCESSION   L08038
KEYWORDS    cytochrome b.
SOURCE      Mitochondrion Lamna nasus (chromosome Mitochondrion Lamna nasus)
            DNA.
  ORGANISM  Mitochondrion Lamna nasus
            Eukaryota; Animalia; Chorqata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Euselachii; Neoselachii; Galeomorphii; Lamniformes;
            Lamnidae.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Martin,A.P. and Palumbi,S.R.
  TITLE     Protein evolution in different cellular environments: cytochrome b
            in sharks and mammals
  JOURNAL   Mol. Biol. Evol. (1993) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             1..1146
                     /product="cytochrome b"
                     /codon_start=1
                     /translation="MAMNIRKTHPLLKIMNHVLIDLPAPSNISIWWNFGSLLGLCLVI
                     QIITGLFLAMHYTADISMAFSSVVHICRDVNYGWLIRNIHANGASLFFVCVYFHIARG
                     LYYGSYLYKETWNIGVILLFLLMATAFVGYVLPWGQMSFWGATVITNLLSAFPYIGDT
                     LVQWIWGGFSVDNATLTRFFAFHFLLPFLIIALMIIHILFLHETGSNNPMGLNSDMDK
                     ISFHPYFSYKDALGFFILLLLLGILTLLLPNLLGDAENFIPANPLVTPPHIKPEWYFL
                     FAYAILRSIPNKLGGVLALLFSILILMLVPLLHTSKQRSSTFRPLTQIFFWTLVANML
                     ILTWIGGQPVEQPFILIGQIASISYFSLFLVVIPLTGWWENKILSLN"
BASE COUNT      300 a    344 c    148 g    354 t
ORIGIN      
        1 atggccataa atatccgaaa aacccatcct ctactaaaaa ttataaacca tgtcctaatt
       61 gaccttccag ccccatcaaa catctccatc tgatgaaact ttggttcact tctaggactg
      121 tgtttagtaa tccaaatcat tacaggtctc ttcttggcaa tacactacac cgcagatatc
      181 tctatagctt tctcttcagt agtccatatt tgtcgtgacg tcaactacgg ctgactcatc
      241 cgtaatattc acgccaacgg agcctctcta ttctttgtct gtgtttactt tcacatcgcc
      301 cgaggactct actatggctc ctacttatat aaagaaacat gaaatatcgg ggtaatccta
      361 ctatttctgc tcatagctac ggccttcgta ggttatgtct taccctgagg ccaaatatcc
      421 ttctgaggcg ctacagtcat cactaacctt ctttccgcct tcccctatat tggagacaca
      481 ctagtccaat gaatctgagg gggcttctca gtagataacg ccaccctcac gcgatttttc
      541 gcatttcact ttctcttgcc cttccttatt attgcactaa taattattca tatcctcttc
      601 ttacacgaaa caggctcaaa caatcctata ggccttaact ccgacataga taaaatctcc
      661 ttccacccct acttctccta caaagacgca cttggattct tcatcctcct cctcctccta
      721 ggaatcctaa ccctattact ccccaacctt ctaggagacg ctgaaaactt catccccgcc
      781 aatcctctcg tcacccctcc tcatattaaa cccgaatgat acttcctatt tgcctatgcc
      841 atcctccgat ccatccccaa taaactagga ggagtcctag cccttctatt ctctatcctc
      901 atcctcatgt tagtccccct tctccacact tccaaacaac gaagcagcac cttccgccca
      961 cttacacaaa ttttcttctg gacccttgtt gccaatatat taattttaac ctgaattggg
     1021 ggtcaaccag ttgaacaacc atttattctt attggacaaa ttgcatctat ttcatacttc
     1081 tctttattcc ttgtcgtaat cccactcaca ggctgatgag aaaataaaat cctcagcctt
     1141 aactag
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human lymphotropic virus type I pol gene, partial cds.
Date: 29 Dec 92 21:26:27 GMT
Distribution: bionet
Checksum: 12532 2

LOCUS       HIVPOLIA      140 bp ds-DNA             VRL       14-DEC-1992
DEFINITION  Human lymphotropic virus type I pol gene, partial cds.
ACCESSION   M99082
KEYWORDS    pol.
SOURCE      Human lymphotropic virus type I (individual_isolate 7ACD) DNA.
  ORGANISM  Human lymphotropic virus type I
            Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
            Retroviridae; Lentivirinae.
REFERENCE   1  (bases 1 to 140)
  AUTHORS   Dube,D.K., Sherman,M.P., Saksena,N.K., Bryz-Gornia,V.,
            Mendelson,J., Arnold,C.B., Spicer,T., Glaser,J.B., Williams,A.E.,
            Nishimura,M., Jacobsen,S. and Poiesz,B.J.
  TITLE     Genetic heterogeneity in human T-cell leukemia/lymphoma virus type
            II
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             <1..>140
                     /gene="pol"
                     /note="putative;  HTLV-I pol gene from base 4779-4918
                     (EMBL numbering system); cloned from PCR product"
                     /codon_start=3
                     /translation="LVERSNGILKTLLYKYFTDKPDLPMDNALSIALWTINHLNVLTN
                     CH"
BASE COUNT       45 a     39 c     19 g     37 t
ORIGIN      
        1 gacttgtaga acgctctaat ggcattctta aaaccctatt atataagtac tttactgaca
       61 aacccgacct acccatggat aatgctctat ccatagccct atggacaatc aaccacctga
      121 atgtgttaac caactgccac
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human germline IgH-chain gene V-region, clone f7.
Date: 21 Dec 92 20:45:05 GMT
Distribution: bionet
Checksum: 02587 3

LOCUS       HUMIGHYAAD    412 bp ds-DNA             PRI       19-NOV-1992
DEFINITION  Human germline IgH-chain gene V-region, clone f7.
ACCESSION   M77300
KEYWORDS    anti-DNA antibody; autoantibody; germline;
            immunoglobulin heavy chain; variable region.
SOURCE      Homo sapiens (individual_isolate Fer) adult DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Olee,T., Yang,P.-M., Siminovitch,K.A., Olsen,N.J., Hillson,J.L.,
            Wu,J., Kozin,F., Carson,D.A. and Chen,P.P.
  TITLE     Molecular basis of an autoantibody-associated restriction fragment
            length polymorphism that confers susceptibility to autoimmune
            diseases
  JOURNAL   J. Clin. Invest. 88, 193-203 (1991)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     intron          <1..100
                     /gene="IGH@"
     iDNA            406..>412
                     /gene="IGH@"
     misc_signal     408..>412
                     /note="7 mer recombination signal"
     CDS             101..405
                     /partial
                     /gene="IGH@"
                     /product="immunoglobulin heavy chain"
                     /codon_start=3
                     /translation="VQCQVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAP
                     GKGLEWVAVISYDGSNKYYADSVKGRFAISRDNSKNTLYLQMNSLRAEDTAVYYCAR"
BASE COUNT      100 a     85 c    128 g     99 t
ORIGIN      
        1 tgattcatgg agaaatagag agactgagtg tgagtgaaca tgagtgagaa aaactggatt
       61 tgtgtggcat tttctgataa cggtgtcctt ctgtttgcag gtgtccagtg tcaggtgcag
      121 ctggtggagt ctgggggagg cgtggtccag cctgggaggt ccctgagact ctcctgtgca
      181 gcctctggat tcaccttcag tagctatgct atgcactggg tccgccaggc tccaggcaag
      241 gggctggagt gggtggcagt tatatcatat gatggaagta ataaatacta cgcagactcc
      301 gtgaagggcc gattcgccat ctccagagac aattccaaga acacgctgta tctgcaaatg
      361 aacagcctga gagctgagga cacggctgtg tattactgtg cgagagacac ag
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens cell division cycle protein 2 (CDC2), 5' flanking
Date: 21 Dec 92 20:44:08 GMT
Distribution: bionet
Checksum: 13377 3

LOCUS       HUMCDC25F    1130 bp ds-DNA             PRI       17-NOV-1992
DEFINITION  Homo sapiens cell division cycle protein 2 (CDC2), 5' flanking
            region.
ACCESSION   L06298
KEYWORDS    cell division cycle protein.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1130)
  AUTHORS   Ku,D.-H., Wen,S.-C., Engelhard,A., Nicolaides,N.C., Lipson,K.E.,
            Marino,T.A. and Calabretta,B.
  TITLE     C-myb transactivates cdc2 expression via Myb binding sites in the
            5' flanking region of the human cdc2 gene
  JOURNAL   J. Biol. Chem. (1992) In press
  STANDARD  full automatic
BASE COUNT      350 a    223 c    252 g    305 t
ORIGIN      
        1 gattgctgga gccaaacaat aaggagacga ttgtctccgc aaacaaacag aaaaaaaaaa
       61 agtaagaaag caagagaggg ggaaggaaag aacaagaaaa aggaaaaaaa aattaactgc
      121 agtaagtgca gaaatctctc tcaaggatat gatggatggc aatgaagaca gagtttttga
      181 cactggatta tttaaagcat aatttaagcc tctttctctc ccctcataga attgtgaatt
      241 tttgtgtttt aattatattt aagccaggcg tggtggcgag tgcctgtagt cgcagctgcg
      301 ctggaggctg aggccgattg cttgagccca ggatttggag gccagcatgc gcaacataat
      361 gagacccagt ctctaaatgc atgcctctct atatattaaa attctgatgt gaaaatattt
      421 taaaatttaa tacatttcaa atgtttttaa ttgtataata aacaaaatgt aaataataaa
      481 ataatttaat attaaattca aaaatgaggt agaaacaaag cacagcgata taaataataa
      541 attttccttt acatttttga ggcggtcttt tgagttttgg atttccttct taaggtcact
      601 gaaatgtgct ccttggagcc agcccgcaaa tcacgcattt agaaaaacat aactatacac
      661 tcctaaccct aagtattaga agtgaaagta atggaatctc gatgtaaaca caatatcact
      721 tttttgatga gctatttaga gtataataaa tttgaactgt gccaatgctg ggagaaaaaa
      781 tttaaaagaa gaacggagcg aacagtagct tcctgctccg ctgactagaa acagcaggac
      841 gacactctcc cgactggagg agagcgcttg cgctcgcact cagttggcgc ccgccctcct
      901 gctttttctc tagccgccct ttcctctttc tttcgcgctc tagccacccg ggaaggccta
      961 cccagcgtag ctgggctctg attggctgct ttgaaagtct acgggctacc cgattggtga
     1021 atccggggcc ctttagcgcg gtgagtttga aactgctcgc acttggcttc aaagctggct
     1081 cttggaaatt gagcggagac gagcggcttg ttgtagctgc cgtgcggccg
//
From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human germline IgH chain gene V-region, clone f1.
Date: 21 Dec 92 20:29:31 GMT
Distribution: bionet
Checksum: 04142 3

LOCUS       HUMIGHYAAA    468 bp ds-DNA             PRI       19-NOV-1992
DEFINITION  Human germline IgH chain gene V-region, clone f1.
ACCESSION   M77297
KEYWORDS    anti-DNA antibody; autoantibody; germline;
            immunoglobulin heavy chain; variable region.
SOURCE      Homo sapiens (individual_isolate Fer) adult peripheral blood
            leukocytes DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Cairns,E., Kwong,P.C., Misener,V., Ip,P., Bell,D.A. and
            Siminovitch,K.A.
  TITLE     Analysis of variable region genes encoding a human anti-dna
            antibody of normal origin: implications for the molecular basis of
            human autoimmune responses
  JOURNAL   J. Immunol. 143, 685-691 (1989)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Olee,T., Yang,P.-M., Siminovitch,K.A., Olsen,N.J., Hillson,J.L.,
            Wu,J., Kozin,F., Carson,D.A. and Chen,P.P.
  TITLE     Molecular basis of an autoantibody-associated restriction fragment
            length polymorphism that confers susceptibility to autoimmune
            diseases
  JOURNAL   J. Clin. Invest. 88, 193-203 (1991)
  STANDARD  full automatic
COMMENT     The IgH variable region 1.9III gene is identical to the Kim4.6 gene
            in Cairns et al. (1989).  Patient had autoimmune disease (lupus or
            rheumatoid arthritis).
FEATURES             Location/Qualifiers
     intron          <1..100
                     /gene="IGH@"
     iDNA            406..>468
                     /gene="IGH@"
     misc_signal     408..414
                     /note="7-mer recombination signal"
                     /gene="IgH"
     misc_signal     438..446
                     /note="9-mer recombination signal"
                     /gene="IgH"
     CDS             101..405
                     /partial
                     /gene="IGH@"
                     /product="immunoglobulin heavy chain"
                     /codon_start=3
                     /translation="VQCQVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAP
                     GKGLEWVAVISYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR"
BASE COUNT      114 a    100 c    147 g    107 t
ORIGIN      chromosome 14
        1 tgattcatgg agaaatagag agactgagtg tgagtgaaca tgagtgagaa aaactggatt
       61 tgtgtggcat tttctgataa cggtgtcctt ctgtttgcag gtgtccagtg tcaggtgcag
      121 ctggtggagt ctgggggagg cgtggtccag cctgggaggt ccctgagact ctcctgtgca
      181 gcctctggat tcaccttcag tagctatgct atgcactggg tccgccaggc tccaggcaag
      241 gggctggagt gggtggcagt tatatcatat gatggaagta ataaatacta cgcagactcc
      301 gtgaagggcc gattcaccat ctccagagac aattccaaga acacgctgta tctgcaaatg
      361 aacagcctga gagctgagga cacggctgtg tattactgtg cgagagacac agtgagggga
      421 agtcattgtg cgcccagaca caaacctccc tgcaggaacg ctgggggg
//