From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human ornithine aminotransferase mRNA, complete cds.
Date: 5 Nov 92 23:12:15 GMT
Distribution: bionet
Checksum: 00273 5

LOCUS       HUMOAT       2013 bp ss-mRNA            PRI       10-NOV-1986
DEFINITION  Human ornithine aminotransferase mRNA, complete cds.
ACCESSION   M12267
KEYWORDS    L-ornithine:2-oxo-acid aminotransferase;
            ornithine aminotransferase; ornithine-oxo-acid aminotransferase.
SOURCE      Human retinoblastoma Y79 cell, cDNA to mRNA, clone lambda-gtRB315.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2013)
  AUTHORS   Inana,G., Totsuka,S., Redmond,M., Dougherty,T., Nagle,J.,
            Shiono,T., Ohura,T., Kominami,E. and Katunuma,N.
  TITLE     Molecular cloning of human ornithine aminotransferase mRNA
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 83, 1203-1207 (1986)
  STANDARD  full automatic
COMMENT     Draft entry and clean copy sequence for [1] kindly provided by
            G.Inana, 30-MAY-1986.
FEATURES             Location/Qualifiers
     mRNA            <1..2013
                     /gene="OAT"
     sig_peptide     55..150
                     /gene="OAT"
                     /codon_start=1
     mat_peptide     151..1371
                     /product="ornithine aminotransferase"
                     /gene="OAT"
                     /codon_start=1
     CDS             55..1374
                     /EC_number="2.6.1.13"
                     /product="ornithine aminotransferase"
                     /codon_start=1
                     /translation="MFSKLAHLQRFAVLSRGVHSSVASATSVATKKTVQGPPTSDDIF
                     EREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSYSAVNQGHCHPKIVNALK
                     SQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTV
                     KGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERA
                     LQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWL
                     AVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAI
                     AALEVLEEENLAENADKLGIILRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWK
                     VCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTILSF"
BASE COUNT      571 a    373 c    445 g    624 t
ORIGIN      EcoRI site.
        1 aattcctgtc ctcaggcgct gtcagatctg tggtttttct acttgaagga cacaatgttt
       61 tccaaactag cacatttgca gaggtttgct gtacttagtc gcggagttca ttcttcagtg
      121 gcttctgcta catctgttgc aactaaaaaa acagtccaag gccctccaac ctctgatgac
      181 atttttgaaa gggaatataa gtatggtgca cacaactacc atcctttacc tgtagccctg
      241 gagagaggaa aaggtattta cttatgggat gtagaaggca gaaaatattt tgacttcctg
      301 agttcttaca gtgctgtcaa ccaagggcat tgtcacccca agattgtgaa tgctctgaag
      361 agtcaagtgg acaaattgac cttaacatct agagctttct ataataacgt acttggtgaa
      421 tatgaggagt atattactaa acttttcaac taccacaaag ttcttcctat gaatacagga
      481 gtggaggctg gagagactgc ctgtaaacta gctcgtaagt ggggctatac cgtgaagggc
      541 attcagaaat acaaagcaaa gattgttttt gcagctggga acttctgggg taggacgttg
      601 tctgctatct ccagttccac agacccaacc agttacgatg gttttggacc atttatgccg
      661 ggattcgaca tcattcccta taatgatctg cccgcactgg agcgtgctct tcaggatcca
      721 aatgtggctg cgttcatggt agaaccaatt cagggtgaag caggcgttgt tgttccggat
      781 ccaggttacc taatgggagt gcgagagctc tgcaccaggc accaggttct ctttattgct
      841 gatgaaatac agacaggatt ggccagaact ggtagatggc tggctgttga ttatgaaaat
      901 gtcagacctg atatagtcct ccttggaaag gccctttctg ggggcttata ccctgtgtct
      961 gcagtgctgt gtgatgatga catcatgctg accattaagc caggggagca tgggtccaca
     1021 tacggtggca atccactagg ctgccgagtg gccatcgcag cccttgaggt tttagaagaa
     1081 gaaaaccttg ctgaaaatgc agacaaattg ggcattatct tgagaaatga actcatgaag
     1141 ctaccttctg atgttgtaac tgccgtaaga ggaaaaggat tattaaacgc tattgtcatt
     1201 aaagaaacca aagattggga tgcttggaag gtgtgtctac gacttcgaga taatggactt
     1261 ctggccaagc caacccatgg cgacattatc aggtttgcgc ctccgctggt gatcaaggag
     1321 gatgagcttc gagagtccat tgaaattatt aacaagacca tcttgtcttt ctgagggtag
     1381 ccagctgttt tcagtggtcc ctgggagcca gctggagaca ggtggtcctg taaaagcttt
     1441 attcctaatg tgggcacatt ccactcccat gagtcttcaa aaactttttt tttgaatata
     1501 tttttttcag ttgatacata atagaacaac gtttatgaac ctgccgtttg ctttgtaacg
     1561 taactaaata atgtaatggc atctatattc agttgaagtg ttttgatgtg catgtgtact
     1621 tcctaaggtg aaatgcatct atatacagac agcctctaaa tcaagtcctt cagtataatt
     1681 gatatatgtt tttataattt cctcactggt ataagtgttt catatttgaa aaagttatct
     1741 ctgggtattg cataaaaggc ttcatcttat aaagtgaaat cattgttatt gaattttagg
     1801 aaggattaat ggttaagtgt atataaaata ctaatattaa gtaaacttca tattggccaa
     1861 caccagggtt gtattctatg gatgtcatta ttttgaatta agaattagtg tttaacattc
     1921 ctaaattgtt ttgagtgctt gattataatt tgtaaaaaat gtttattttc aatacttctt
     1981 taaatttaaa ataaagctta tatttcaaat gtc
//