From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human alpha-N-acetylgalactosaminidase mRNA, complete cds.
Date: 29 Jul 92 10:02:45 GMT
Distribution: bionet
Checksum: 03403     5

LOCUS       HUMNAGB      1821 bp ss-mRNA            PRI       29-JUL-1992
DEFINITION  Human alpha-N-acetylgalactosaminidase mRNA, complete cds.
ACCESSION   M38083
KEYWORDS    alpha-N-acetylgalactosaminidase; lysosomal hydrolase.
SOURCE      Human fibroblast, cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1821)
  AUTHORS   Yamauchi,T., Hiraiwa,M., Kobayashi,H., Uda,Y., Miyatake,T. and
            Tsuji,S.
  TITLE     Molecular cloning of two species of cDNAs for human
            alpha-N-acetylgalactosaminidase and expression in mammalian cells
  JOURNAL   Biochem. Biophys. Res. Commun. 170, 231-237 (1990)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     CDS             73..1308
                     /EC_number="3.2.1.49"
                     /product="alpha-N-acetylgalactosaminidase"
                     /codon_start=1
                     /translation="MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDE
                     DPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGI
                     PFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFS
                     TPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDI
                     QDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVL
                     AAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNK
                     ASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINP
                     SGVVMWYLYPIKNLEMSQQ"
     sig_peptide     73..123
                     /EC_number="3.2.1.49"
                     /product="alpha-N-acetylgalactosaminidase"
                     /codon_start=1
     mat_peptide     124..1305
                     /EC_number="3.2.1.39"
                     /product="alpha-N-acetylgalactosaminidase"
                     /codon_start=1
BASE COUNT      398 a    539 c    485 g    399 t
ORIGIN
        1 cagagcccaa cacatacagc tgatacacgc agaccagatc tggtcaggtc ctcggaagct
       61 gagtccagag cgatgctgct gaagacagtg ctcttgctgg gacatgtggc ccaggtgctg
      121 atgctggaca atgggctcct gcagacacca cccatgggct ggctggcctg ggaacgcttc
      181 cgctgcaaca ttaactgtga tgaggaccca aagaactgca taagtgaaca gctcttcatg
      241 gagatggctg accggatggc acaggatgga tggcgggaca tgggctacac atacctcaac
      301 attgatgact gctggatcgg tggtcgcgat gccagtggcc gcctgatgcc ggatcccaag
      361 cgcttccctc atggcattcc tttcctggct gactacgttc actccctggg cctgaagttg
      421 ggtatctacg cggacatggg caacttcacc tgcatgggtt acccaggcac cacactggac
      481 aaggtggtcc aggatgctca gaccttcgcc gagtggaagg tagacatgct caagctggat
      541 ggctgcttct ccacccccga ggagcgggcc caggggtacc ccaagatggc tgctgccctg
      601 aatgccacag gccgccccat cgccttctcc tgcagctggc cagcctatga aggcggcctc
      661 cccccaaggg tgaactacag tctgctggcg gacatctgca acctctggcg taactatgat
      721 gacatccagg actcctggtg gagcgtgctc tccatcctga attggttcgt ggagcaccag
      781 gacatactgc agccagtggc cggccctggg cactggaatg accctgacat gctgctcatt
      841 gggaactttg gtctcagctt agagcaatcc cgggcccaga tggccctgtg gacggtgctg
      901 gcagcccccc tcttgatgtc cacagacctg cgtaccatct ccgcccagaa catggacatt
      961 ctgcagaatc cactcatgat caaaatcaac caggatccct taggcatcca gggacgcagg
     1021 attcacaagg aaaaatctct catcgaagtg tacatgcggc ctctgtccaa caaggctagc
     1081 gccttagtct tcttcagctg caggaccgat atgccttatc gctaccactc ctcccttggc
     1141 cagctgaact tcaccgggtc tgtgatatat gaggcccagg acgtctactc aggtgacatc
     1201 atcagtggcc tccgagatga aaccaacttc acagtgatca tcaacccttc aggggtagtg
     1261 atgtggtacc tgtatcccat caagaacctg gagatgtccc agcagtgagg agctgggaca
     1321 tgtgacaggc tgtggtggca ccactgagcc tagaccatgg agccttggca tgcccagggc
     1381 aagtggggag gttctctgct ccccaggcct gctcggtgac tgaccccatc atacccaaag
     1441 tgcaatctca cggccaggtt ctatgccctg tccaagcgta aaccctcttg gaaacttctt
     1501 ttggggcaat tttcctgtgg ccttcctggc ctctacttcc atgtgcgcag ccccacagac
     1561 gttgctgagc aactcgccag cctcctgagc tccatgccca tcaggactct agcctctgac
     1621 cttgctgttg actctgaaat caggatttgg aagttttcga attaggagta gagagatctg
     1681 acctcttgcc aggaatgccc atggatcatg tgattggctt ttctacccat agagggcctt
     1741 gcagcctgat accacctggg agtgagggtc acaaaggaga ccttggctcc ctcaggtcac
     1801 caataaacct gttctttaat c
//