From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.norvegicus promoter region of mEH gene for microsomal epoxide
Date: 21 Jul 92 10:08:12 GMT
Distribution: bionet
Checksum: 17023     4

LOCUS       RATPMEH      1298 bp ds-DNA             ROD       21-JUL-1992
DEFINITION  R.norvegicus promoter region of mEH gene for microsomal epoxide
            hydrolase
ACCESSION   X55186
KEYWORDS    epoxide hydrolase.
SOURCE      Rattus norvegicus DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Kondo,S., Carr,B.I., Takagi,K., Huang,T.H., Chou,Y.M., Yokoyama,K.
            and Itakura,K.
  TITLE     Expression of rat microsomal epoxide hydrolase gene during liver
            chemical carcinogenesis.
  JOURNAL   Cancer Res. 50, 6222-6228 (1990)
  STANDARD  full automatic
COMMENT     *source: strain=Sprague-Dawley; *source: stage=adult; *source:
            tissue=regenerating liver; *source: sub_strain=F344; *source: sex=
            M;
            From EMBL    entry RNPMEH;  dated 10-JUN-1992.
FEATURES             Location/Qualifiers
     repeat_region   457..554
                     /rpt_type=tandem
                     /note="regulatory element"
     misc_binding    585..590
                     /bound_moiety="SP1"
     enhancer        646..653
                     /note="HBV enhancer core sequence"
     misc_binding    663..670
                     /bound_moiety="AP-2 protein"
     misc_binding    710..717
                     /bound_moiety="AP-2 protein"
     enhancer        1015..1023
                     /note="core sequence"
     misc_feature    1128
                     /note="transcriptional start site"
BASE COUNT      395 a    270 c    276 g    357 t
ORIGIN
        1 ctgcagaagc aatgcagcgg ctactggagg ctaatcagaa ataacattcc tgcgcgcctt
       61 tattacctgt tattaagtaa taagcagtgg tcaagtgcag tgaaccgaga cattgcagcc
      121 agtcctgttg tgtagtccag gaggccagtg actccaaggc caatgactta tacttgagca
      181 aagtacaaca tcattttaca tagtggataa tactaatatt cttctgacct ggattatcta
      241 agaaacaaag cctttaagtt actcttttgc tctgttgctt gtaccccaac tatatcttga
      301 gctttttgga gaacaatact caagacacca cttagatgct gttactaagt gacacagagt
      361 tacttgaatt caagttcacc attgtgatca ctaggtgccc ctatataact aatggatata
      421 catagtgtat atcatttaaa aaagaataat gaatgaatac atagtgtata catcataatg
      481 gatacatagt gtatacatca taatggatac atagtgtata catcataatg gatacatagt
      541 gtatacatca taattacatt gaacaaaaga atcatttaca acctgggcgg gatggaacag
      601 gacaggggag ataccaccat ttatgtcacc actttggggt ttcgttgttt gcttggagtc
      661 tcttggggat ggagagaatg taaagaggta aaagaacaac cttctagagt tggggatcta
      721 tgtggatccc aagatcaaac atagtctatc agacttagca gcaagtgcct ttactcgctg
      781 agccttctca ccagactaat acacagtttt aaaccaagaa ttatttctaa aaatgtctgt
      841 ttatactttc aggccacagt cgtccatggg taaacaaaac ctcgaataag gaatgggcac
      901 tggggcaaga ccaacatgag tcatcctaat gacctttgcc tatattctgt gggggttttt
      961 tttcttccaa tggagctcca gcactggatc ctccaggtca ctgtcactgt cactgtggtt
     1021 cagtttgctg tctaaagtcc agggtgataa ctgccctgtg tgcacaacag atcatctgag
     1081 tcattggggc tatgaaagca taaaaagtca ggtttggtag gaatcacact cagccactct
     1141 cacttcgtgc tgtgaccagg gaggactcac ggagcctaca cttagccctg gtaaacagca
     1201 gagcatgctg ggataattct tcccagaaaa ggaaaagcag gcacttctgt tcccagggaa
     1261 aacaacagga gcactttgga cctccctgct gcagtcag
//