From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for mitotic kinesin-like protein-1
Date: 29 Dec 92 01:00:46 GMT
Distribution: bionet
Checksum: 41692 7

LOCUS       HUMMKLP1     3258 bp ss-RNA             PRI       04-DEC-1992
DEFINITION  H.sapiens mRNA for mitotic kinesin-like protein-1
ACCESSION   X67155
KEYWORDS    ATPase; MKLP-1 gene; kinesin-like protein;
            microtubule-associated protein; mitotic protein.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3258)
  AUTHORS   Nislow,C.E., Lombillo,V.A., Kuriyama,R. and McIntosh,J.R.
  TITLE     A plus-end-directed motor enzyme that moves antiparallel
            microtubules in vitro localizes to the interzone of mitotic
            spindles
  JOURNAL   Nature 359, 543-547 (1992)
  STANDARD  full automatic
COMMENT     *source: cell_type=HeLa cells;
               From EMBL    entry HSMKLP1;  dated 21-OCT-1992.
FEATURES             Location/Qualifiers
     CDS             77..2959
                     /gene="MKLP-1"
                     /product="mitotic kinase-likeprotein-1"
                     /codon_start=1
                     /translation="MLSARAKTPRKPTVKKGPKRTLKTQLGYCRVRLGFPDQECCIEV
                     INNTTVQLHTPEGYRLNRNGDYKETQYSFKQVFGTHTTQKELFDVVANPLVNDLIHGK
                     NGLLFTYGVTGSGKTHTMTGSPGEGGLLPRCLDMIFNSIGSFQAKRYVFKSNDRNSMD
                     IQCEVDALLERQKREAMPNPKTSSSKRQVDPEFADMITVQEFCKAEEVDEDSVYGVFV
                     SYIEIYNNYIYDLLEEVPFDPINPNLHNLNCFVKIKNHNMYVAGCTEVEVKSTEEAFE
                     VFWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLV
                     DLAGSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTNKMVPYRDSKLT
                     HLFKNYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARPVDKAICGLTPG
                     RRYRNQPRGPVGNEPLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQM
                     MIDEFNKQSNAFKALLQEFDNAVLSKENHMQGKLNEKEKMISGQKLEIERLEKKNKTL
                     EYKIEILEKTTTIYEEDKRNLQQELETQNQKLQRQFSEKRRLEARLQGMVTETTMKWE
                     KECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTEKPERPSRERDREKVTQRSVS
                     PSPVPLLFQPDQNAPPIRLRHRRSRSAGDRWVDHKPASNMQTETVMQPHVPHAITVSV
                     ANEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPN
                     GSRKRRSSTVAPAQPDGAESEWTRCRNKVFCGCEMRAGSQLDLISASRHNPSAKSHET
                     DSPSTERTFSFVWMISRKPCQKQSSRSSCRTPALVENHGPQLHHTLTQNKAFPMVPKT
                     TSIQQTLYSVCFAIFNINSRGRLLFSSLYEFFIMFFLKYISCILIN"
BASE COUNT     1111 a    598 c    702 g    847 t
ORIGIN      
        1 ttcgtgatgg attcagtact cctcaaccac tcttcctaat gattggaaca aaagaaaaaa
       61 aaaagaaaaa aaagccatgt tgtcagcgag agctaagaca ccccggaaac ctaccgtgaa
      121 aaagggtccc aaacgaacct taaagaccca gttgggatac tgtagggtgc gactgggctt
      181 tcctgatcaa gagtgttgca tagaagtgat caataataca actgttcagc ttcatactcc
      241 tgagggctac agactcaacc gaaatggaga ctataaggag actcagtatt catttaaaca
      301 agtatttggc actcacacca cccagaagga actctttgat gttgtggcta atcccttggt
      361 caatgacctc attcatggca aaaatggtct tctttttaca tatggtgtga cgggaagtgg
      421 aaaaactcac acaatgactg gttctccagg ggaaggaggg ctgcttcctc gttgtttgga
      481 catgatcttt aacagtatag ggtcatttca agctaaacga tatgttttca aatctaatga
      541 taggaatagt atggatatac agtgtgaggt tgatgcctta ttagaacgtc agaaaagaga
      601 agctatgccc aatccaaaga cttcttctag caaacgacaa gtagatccag agtttgcaga
      661 tatgataact gtacaagaat tctgcaaagc agaagaggtt gatgaagata gtgtctatgg
      721 tgtatttgtc tcttatattg aaatatataa taattacata tatgatctat tggaagaggt
      781 gccgtttgat cccataaacc caaacctcca caatctaaat tgcttcgtga agattaagaa
      841 ccataacatg tatgttgcag gatgtacaga agttgaagtg aaatctactg aggaggcttt
      901 tgaagttttc tggagaggcc agaaaaagag acgtattgct aatacccatt tgaatcgtga
      961 gtccagccgt tcccatagcg tgttcaacat taaattagtt caggctccct tggatgcaga
     1021 tggagacaat gtcttacagg aaaaagaaca aatcactata agtcagttgt ccttggtaga
     1081 tcttgctgga agtgaaagaa ctaaccggac cagagcagaa gggaacagat tacgtgaagc
     1141 tggtaatatt aatcagtcac taatgacgct aagaacatgt atggatgtcc taagagagaa
     1201 ccaaatgtat ggaactaaca agatggttcc atatcgagat tcaaagttaa cccatctgtt
     1261 caagaactac tttgatgggg aaggaaaagt gcggatgatc gtgtgtgtga accccaaggc
     1321 tgaagattat gaagaaaact tgcaagtcat gagatttgcg gaagtgactc aagaagttga
     1381 agtagcaaga cctgtagaca aggcaatatg tggtttaacg cctgggagga gatacagaaa
     1441 ccagcctcga ggtccagttg gaaatgaacc attggttact gacgtggttt tgcagagttt
     1501 tccacctttg ccgtcatgcg aaattttgga tatcaacgat gagcagacac ttccaaggct
     1561 gattgaagcc ttagagaaac gacataactt acgacaaatg atgattgatg agtttaacaa
     1621 acaatctaat gcttttaaag ctttgttaca agaatttgac aatgctgttt taagtaaaga
     1681 aaaccacatg caagggaaac taaatgaaaa ggagaagatg atctcaggac agaaattgga
     1741 aatagaacga ctggaaaaga aaaacaaaac tttagaatat aagattgaga ttttagagaa
     1801 aacaactact atctatgagg aagataaacg caatttgcaa caggaacttg aaactcagaa
     1861 ccagaaactt cagcgacagt tttctgagaa acgcagatta gaagccaggt tgcaaggcat
     1921 ggtgacagaa acgacaatga agtgggagaa agaatgtgag cgtagagtgg cagccaaaca
     1981 gctggagatg cagaataaac tctgggttaa agatgaaaag ctgaaacaac tgaaggctat
     2041 tgttactgaa cctaaaactg agaagccaga gagaccctct cgggagcgag atcgagaaaa
     2101 agttactcaa agatctgttt ctccatcacc tgtgccttta ctctttcaac ctgatcagaa
     2161 cgcaccacca attcgtctcc gacacagacg atcacgctct gcaggagaca gatgggtaga
     2221 tcataagccc gcctctaaca tgcaaactga aacagtcatg cagccacatg tccctcatgc
     2281 catcacagta tctgttgcaa atgaaaaggc actagctaag tgtgagaagt acatgctgac
     2341 ccaccaggaa ctagcctccg atggggagat tgaaactaaa ctaattaagg gtgatattta
     2401 taaaacaagg ggtggtggac aatctgttca gtttactgat attgagactt taaagcaaga
     2461 atcaccaaat ggtagtcgaa aacgaagatc ttccacagta gcacctgccc aaccagatgg
     2521 tgcagagtct gaatggacgc gatgtagaaa caaggtgttc tgtggctgtg agatgagagc
     2581 aggatcccag ctggacctga tatcagcatc acggcacaac ccaagcgcaa aaagccatga
     2641 aactgacagt cccagtactg aaagaacatt ttcatttgtg tggatgattt ctcgaaagcc
     2701 atgccagaag cagtcttcca ggtcatcttg tagaactcca gctttggttg aaaatcacgg
     2761 acctcagcta catcatacac tgacccagaa taaagctttc cctatggttc caaagacaac
     2821 tagtattcaa caaaccttgt atagtgtatg ttttgccata tttaatatta atagcagagg
     2881 aagactcctt ttttcatcac tgtatgaatt ttttataatg ttttttttaa aatatatttc
     2941 atgtatactt ataaactaat tcacacaagt gtttgtctta gatgattaag gaagactata
     3001 tctagatcat gtctgatttt ttattgtgac ttctccagcc ctggtctgaa tttcttaagg
     3061 ttttataaac aaatgctgct atttattagc tgcaagaatg cactttagaa ctatttgaca
     3121 attcagactt tcaaaataaa gatgtaaatg actggccaat aataaccatt ttaggaaggt
     3181 gttttgaatt ctgtatgtat atattcactt tctgacattt agatatgcca aaagaattaa
     3241 aatcaaaagc actaaggg
//