From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human pancreatic beta-cell glucokinase mRNA, complete cds.
Date: 22 Jul 92 10:02:51 GMT
Distribution: bionet
Checksum: 37778     5

LOCUS       HUMBGLUKIN   2585 bp ss-mRNA            PRI       22-JUL-1992
DEFINITION  Human pancreatic beta-cell glucokinase mRNA, complete cds.
ACCESSION   M88011
KEYWORDS    glucokinase.
SOURCE      Homo sapiens adult cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2585)
  AUTHORS   Nishi,S., Stoffel,M., Xiang,K.-s., Shows,T.B., Bell,G.I. and
            Takeda,J.
  TITLE     Human pancreatic beta-cell glucokinase: cDNA sequence and
            localization of the polymorphic gene to chromosome 7, band p13
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             330..1727
                     /product="glucokinase"
                     /gene="GCK"
                     /codon_start=1
                     /translation="MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRG
                     LRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVK
                     TKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDID
                     KGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDH
                     QCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRL
                     VDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRF
                     VSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINR
                     MRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAA
                     LVSAVACKKACMLGQ"
BASE COUNT      578 a    740 c    826 g    441 t
ORIGIN
        1 ggacactaag ccccacagct caacacaacc aggagagaaa gcgctgagga cgccacccaa
       61 gcgcccagca atggccctgc ctggagaaca tccaggctca gtgaggaagg gtccagaagg
      121 gaatgcttgc cgactcgttg gagaacaatg aaaaggagga aactgtgact gaacctcaaa
      181 ccccaaacca gcccgaggag aaccacattc tcccagggac ccagggcggg ccgtgacccc
      241 tgcggcggag aagccttgga tatttccact tcagaagcct actggggaag gctgaggggt
      301 cccagctccc cacgctggct gctgtgcaga tgctggacga cagagccagg atggaggccg
      361 ccaagaagga gaaggtagag cagatcctgg cagagttcca gctgcaggag gaggacctga
      421 agaaggtgat gagacggatg cagaaggaga tggaccgcgg cctgaggctg gagacccatg
      481 aagaggccag tgtgaagatg ctgcccacct acgtgcgctc caccccagaa ggctcagaag
      541 tcggggactt cctctccctg gacctgggtg gcactaactt cagggtgatg ctggtgaagg
      601 tgggagaagg tgaggagggg cagtggagcg tgaagaccaa acaccagatg tactccatcc
      661 ccgaggacgc catgaccggc actgctgaga tgctcttcga ctacatctct gagtgcatct
      721 ccgacttcct ggacaagcat cagatgaaac acaagaagct gcccctgggc ttcaccttct
      781 cctttcctgt gaggcacgaa gacatcgata agggcatcct tctcaactgg accaagggct
      841 tcaaggcctc aggagcagaa gggaacaatg tcgtggggct tctgcgagac gctatcaaac
      901 ggagagggga ctttgaaatg gatgtggtgg caatggtgaa tgacacggtg gccacgatga
      961 tctcctgcta ctacgaagac catcagtgcg aggtcggcat gatcgtgggc acgggctgca
     1021 atgcctgcta catggaggag atgcagaatg tggagctggt ggagggggac gagggccgca
     1081 tgtgcgtcaa taccgagtgg ggcgccttcg gggactccgg cgagctggac gagttcctgc
     1141 tggagtatga ccgcctggtg gacgagagct ctgcaaaccc cggtcagcag ctgtatgaga
     1201 agctcatagg tggcaagtac atgggcgagc tggtgcggct tgtgctgctc aggctcgtgg
     1261 acgaaaacct gctcttccac ggggaggcct ccgagcagct gcgcacacgc ggagccttcg
     1321 agacgcgctt cgtgtcgcag gtggagagcg acacgggcga ccgcaagcag atctacaaca
     1381 tcctgagcac gctggggctg cgaccctcga ccaccgactg cgacatcgtg cgccgcgcct
     1441 gcgagagcgt gtctacgcgc gctgcgcaca tgtgctcggc ggggctggcg ggcgtcatca
     1501 accgcatgcg cgagagccgc agcgaggacg taatgcgcat cactgtgggc gtggatggct
     1561 ccgtgtacaa gctgcacccc agcttcaagg agcggttcca tgccagcgtg cgcaggctga
     1621 cgcccagctg cgagatcacc ttcatcgagt cggaggaggg cagtggccgg ggcgcggccc
     1681 tggtctcggc ggtggcctgt aagaaggcct gtatgctggg ccagtgagag cagtggccgc
     1741 aagcgcaggg aggatgccac agccccacag cacccaggct ccatggggaa gtgctcccca
     1801 cacgtgctcg cagcctggcg gggcaggagg cctggccttg tcaggaccca ggccgcctgc
     1861 cataccgctg gggaacagag cgggcctctt ccctcagttt ttcggtggga cagccccagg
     1921 gccctaacgg gggtgcggca ggagcaggaa cagagactct ggaagccccc cacctttctc
     1981 gctggaatca atttcccaga agggagttgc tcactcagga ctttgatgca tttccacact
     2041 gtcagagctg ttggcctcgc ctgggcccag gctctgggaa ggggtgccct ctggatcctg
     2101 ctgtggcctc acttccctgg gaactcatcc tgtgtgggga ggcagctcca acagcttgac
     2161 cagacctaga cctgggccaa aagggcagcc aggggctgct catcacccag tcctggccat
     2221 tttcttgcct gaggctcaag aggcccaggg agcaatggga gggggctcca tggaggaggt
     2281 gtcccaagct ttgaataccc ccagagacct tttctctccc ataccatcac tgagtggctt
     2341 gtgattctgg gatggaccct cgcagcaggt gcaagagaca gagcccccaa gcctctgccc
     2401 caaggggccc acaaagggga gaagggccag ccctacatct tcagctccca tagcgctggc
     2461 tcaggaagaa accccaagca gcattcagca caccccaagg gacaacccca tcatatgaca
     2521 tgccaccctc tccatgccca acctaagatt gtgtgggttt tttaattaaa aatgttaaaa
     2581 gtttt
//