From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: neurocan=chondroitin sulfate proteoglycan [rats, brain, mRNA, 5191
Date: 3 Jan 93 22:20:13 GMT
Distribution: bionet
Checksum: 60501 10

LOCUS       S113931      5191 bp    mRNA            ROD       24-NOV-1992
DEFINITION  neurocan=chondroitin sulfate proteoglycan [rats, brain, mRNA, 5191
            nt]
ACCESSION   S45374 M97161
KEYWORDS    .
SOURCE      rats brain
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 5191)
  AUTHORS   Rauch,U., Karthikeyan,L., Maurel,P., Margolis,R.U. and
            Margolis,R.K.
  TITLE     Cloning and primary structure of neurocan, a developmentally
            regulated, aggregating chondroitin sulfate proteoglycan of brain.
  JOURNAL   J. Biol. Chem. 267, 19536-19547 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 113931] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 4.
FEATURES             Location/Qualifiers
     CDS             77..3850
                     /note="chondroitin sulfate proteoglycan;  For the protein
                     sequence (NCBI gibbsq 113933):  Method: conceptual
                     translation with partial peptide sequencing.  This
                     sequence comes from Fig. 4."
                     /product="neurocan"
                     /codon_start=1
                     /translation="MGAESVWASGLLVLWLLLLVSGDQDTQDTTTTEKGLHMLKSGSG
                     PIQAALAELVALPCFFTLQPRQSPLGDIPRIKWTKVQTASGQRQDLPILVAKDNVVRV
                     AKGWQGRVSLPAYPRHRANATLLLGPLRASDSGLYRCQVVKGIEDEQDLVTLEVTGVV
                     FHYRAARDRYALTFAEAQEACHLSSATIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYP
                     ITQSRPGCYGDRSSLPGVRSYGRRDPQELYDVYCFARELGGEVFYVGPARRLTLAGAR
                     ALCQRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGSAPGVRTV
                     YRFANRTGFPAPGARFDAYCFRAHHHTPQRGDSEIPSSGDEGEIVSAEGPPAPELKPR
                     LGEQEVITPDFQEPLVSSGEDEPLDLTRTQASQETLASTPGGPTLASWLLTGVTSSTG
                     VPSPSSLGVDMEETTPSGTQVAPTPTMRRGRFKGLNGRHFQQQGPEDQLLEAAEASAQ
                     PPTLEVTADHMGPSAATEALESDQSHSPWAILTNEVDVPGAGSLGSRSLPESRKWSPS
                     LISPSTVPSTDSTPGLKPGADEAPGVKSAIHHPPWLPSEPAVPSSIPSEALSAVSLQA
                     SPGDGSPDFPIVAMLRAPKLWLLPHSTLVPNVSPIPLSPASPLPSSVPEEQAVRPVSF
                     GAEDPETPFQTTMAAPGEASHGSPEADSIEIEGISSMQATKHPISGPWASLDSSNVTV
                     NPVPSDAGILGTESGVLDLPGSPTSDGQATVDMVLATWLPLPGHGLDTGSQSTPMEAH
                     GVTMSVEPTVALEGGATKDPMEATMDVVPSTVDATSGSEPKSSISSTHVVVTAAGDQG
                     TPTLTPTSSEGQVVAQESLGTLTSLPSHPWSSLASSMDEVASVSSGEPTRLWDIPSTL
                     IPVSLGLDESDLKVVAESPGLEGFWEEVASGQEDPTDPCENNPCLHGGTCRTNGTMYG
                     CSCDQGYAGENCEIDIDDCLCSPCENGGTCIDEVNGFICLCLPSYGGNLCEKDTEGCD
                     RGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGHENSWIGL
                     NDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHENGRWNDVPCNYNLP
                     YVCKKGTVLCGPPPAVENASLVGVRKVKYNVHATVRYQCDEGFSQHHVATIRCRSNGK
                     WDRPQIVCTKPRRSHRMRRHHHHPHRHHKPRKEHRKHKRHPAEDWEKDEGDFC"
BASE COUNT     1104 a   1533 c   1460 g   1094 t
ORIGIN      
        1 aacaccggag ccaggcgtcg cgtcctttgt gcccggaacc gtggggatgt gtccgcgcta
       61 aggagccagc tccagtatgg gggccgaatc tgtctgggcc tcaggcctcc tggtgctgtg
      121 gctgcttctc ctagtgtctg gggatcagga cacacaggac accaccacca cggaaaaggg
      181 gcttcacatg ctgaagtcgg ggtcaggacc catccaggct gctttggcag agttagtggc
      241 cctgccctgc ttctttaccc ttcaaccacg gcaaagcccc ctgggagaca ttcctcggat
      301 caagtggacg aaagttcaga ctgcatcagg ccagcgacag gatttgccaa tcttggtggc
      361 caaagacaat gtggtgcgtg tggccaaggg ctggcaggga cgggtgtcat tgcctgccta
      421 tccccggcac agagccaatg ctacacttct gttggggcca ctgcgagcca gtgactctgg
      481 gctgtatcgc tgccaagtgg tgaagggtat cgaggatgag caggacctgg taaccctgga
      541 agtgacgggc gtcgtgttcc attatcgggc ggcccgggac cgctatgcgt tgaccttcgc
      601 tgaggcccag gaggcttgtc acctgagctc cgctaccatt gcggctccaa ggcacctgca
      661 ggctgcgttc gaagatggct ttgacaactg cgatgcgggc tggctctcag accgcacggt
      721 ccggtacccg atcactcagt cgcgtcccgg ttgctatggt gatcgcagca gcctgccagg
      781 tgtccggagc tacgggagac gcgacccgca ggaactctac gatgtctact gctttgcccg
      841 cgagctaggg ggtgaagtct tttacgtggg ccccgcccgc cgactgaccc tggcgggggc
      901 gcgggcactg tgtcagcgtc agggtgcagc gctggcctcc gtgggacagt tgcacctggc
      961 ctggcacgag ggcctggacc agtgcgaccc gggctggctg gcagacggca gcgtgcgcta
     1021 cccgatccag actccacggc ggcgttgcgg gggctccgct ccaggtgtgc gcacagtgta
     1081 ccgcttcgcc aaccgcactg gctttcctgc gccaggagcc cgcttcgacg cctactgctt
     1141 ccgagctcat caccatacac cacaacgtgg ggactccgag atcccctcat ctggagatga
     1201 gggggagatt gtgtcagcag aggggccgcc agccccagaa ctaaagccca gattggggga
     1261 gcaggaggtg ataacacctg acttccagga acctctcgta tccagtggag aagatgaacc
     1321 cctagatttg acaaggacac aagcatctca ggagacgctc gcctctaccc cagggggtcc
     1381 cacactggct tcatggctgc ttacaggtgt cacaagctcc acgggtgtcc ccagccccag
     1441 cagcctggga gtagacatgg aagagacaac accctcaggc acacaggtag cccccacccc
     1501 cacaatgagg aggggccgct ttaaagggtt gaatggtcga cacttccagc aacagggccc
     1561 agaagaccag cttctggagg cagcagaggc cagtgcccag cctcccaccc tggaagttac
     1621 tgctgaccac atggggcctt ctgcagccac agaggccttg gagagtgacc agagccacag
     1681 tccttgggcc attctgacca atgaagtgga tgtgccaggg gcaggctctc ttggcagcag
     1741 gagtctccca gagtcccgga agtggtcccc gtcgctgatt tcacccagta ctgtcccgag
     1801 cactgacagt actcctggcc tgaagccagg ggcagatgag gcccctggtg tgaagtcagc
     1861 catccaccac ccaccctggt tgccctcaga acccgctgtc ccatcctcca ttccctcaga
     1921 ggccctaagt gctgtctccc tacaggcatc ccctggtgat ggctctccag acttccccat
     1981 tgtagccatg cttcgagccc ccaaactgtg gcttctgcca cactctacac tcgtcccgaa
     2041 tgtgtcccca atcccactct ccccagcttc tccactcccc tcctcggtcc cagaagaaca
     2101 ggctgtcaga cctgtcagct ttggagcaga agaccccgag accccatttc agaccaccat
     2161 ggctgcccca ggtgaagcca gccacggatc ccctgaggca gactccatag aaatcgaggg
     2221 gatcagctcc atgcaggcta caaagcaccc catctctggc ccatgggctt ctttggactc
     2281 cagtaatgtg acagtgaatc ctgtcccttc tgatgctggc atcctaggga ctgagtctgg
     2341 ggtcttggac ttaccaggga gtcccacatc agacggacag gccactgtgg acatggtgct
     2401 ggccacctgg ctaccactgc ctggccacgg actggacact ggctcccagt ccacacccat
     2461 ggaagcccat ggagtaacca tgagtgtgga acctacagtg gctttggaag gaggtgccac
     2521 caaagaccca atggaggcca ccatggatgt ggtccccagc actgttgatg ccacttcggg
     2581 gtctgaaccc aaaagttcca tttctagcac ccatgtggtt gtgactgcag ctggggacca
     2641 gggcacaccc acactgaccc ctacaagctc tgaaggtcag gtggtggccc aggagtcact
     2701 gggaaccctc accagtctgc cttctcatcc ctggtcatct ctggcctcca gcatggacga
     2761 agtggcctcg gtttcctcag gagaacccac aaggttgtgg gacatcccca gcactctgat
     2821 acctgtgtcc ttgggcttgg atgaatcaga cctgaaggtt gtggctgaga gcccaggctt
     2881 ggagggcttc tgggaagagg tggccagtgg gcaggaagac cccacggatc cctgcgagaa
     2941 caacccttgt ctgcacgggg gcacctgccg cacaaatggc accatgtacg gctgtagttg
     3001 tgatcagggc tatgctgggg agaattgtga aattgacatt gatgactgct tgtgcagccc
     3061 ttgtgagaat gggggtacct gcattgatga ggtgaatggt ttcatctgcc tctgtctccc
     3121 cagctatggg ggcaacctgt gcgagaagga cacagaagga tgcgaccgtg gctggcacaa
     3181 attccagggc cactgctacc gctactttgc tcatcggcgg gcctgggagg acgcagagag
     3241 agactgcagg cgccgagccg gccacctgac aagtgtccac tccccagaag agcacaagtt
     3301 tattaacagt tttggacacg agaattcatg gattggcctg aatgacagga cagtagagag
     3361 ggacttccag tggacagaca acacaggact gcaatatgag aactggagag agaagcagcc
     3421 ggataatttc ttcgcaggtg gggaggattg tgtggtgatg gtggcgcatg agaatggacg
     3481 ctggaatgat gtcccctgta actacaacct cccctacgtc tgcaagaagg gtacagtgct
     3541 gtgtgggccc cctccagcag tggagaatgc ctctcttgtt ggtgtgcgca aggtcaagta
     3601 caatgtccat gccactgtgc gataccagtg tgatgaagga ttctcccagc accatgtggc
     3661 taccatccga tgccgaagca atgggaagtg ggaccggcct cagattgtgt gcaccaagcc
     3721 caggcggtca catcggatgc gtcgacacca ccaccatcca caccggcatc acaagccacg
     3781 caaggagcac agaaaacaca agagacaccc agcggaagac tgggagaaag atgaagggga
     3841 tttctgctaa cgatccagac taatcaagca caagctccca cacctcctcc agagcattcc
     3901 cctggggacc cagaacccag acaaccacca gagagagggt ggggacaccc tggagcccca
     3961 cacccctgca gtcggtcctc tgtacaaagc tcagatcacc ctctccttcc ttactgaggt
     4021 cctcctggca ggggtggcgg gacctgagag gccattctgg tctggctgag cccttaggat
     4081 tacttcccag ctgtcaaagg gagtctcgaa gtctgtatcc atgaggggca aacagtatgt
     4141 ctgtgggcgc tgggtagtga ctttcacacc agagattcag gcttcgtaaa cagcggacta
     4201 tactgaatcc atggcaaacc tttggttaaa gtcactgtat ttgagtggag gaccagcaga
     4261 gcaaacagga tgctctgtgg tcccctggga tcccctaagg gcaggcttcc atccctccgt
     4321 ctttcttttt tccctttctc cttcctccct ctcaattcca acactgtcag gactcaacct
     4381 aggctgggct tgaactgact attgtagaag gatgtccttg aagtctcaat cctcctgccc
     4441 ctgtgccacc atgcctacct ggtttatttg gtgctggaca tggaacccag cgctgggcaa
     4501 gtgctctctc tactaaccag ctctggtctt tggtcttggt gcagaccact aaatctagtg
     4561 tgggaactct tgtatattga attttagtga tgtctcttag cctggcctcc gtggcttcct
     4621 aggggaggtt cctcagagca atgggggtgg ggagggttac tctattgctg actccccacg
     4681 tctagtgcag cgctgagatc tggtggttct attttgggtt gtttttgttt tgagacaggg
     4741 cctcactgtg cagctctagc tggcctggaa cttgctatgt agaccaggct agcctggaac
     4801 tcagcgatct gtctgcctct gcctctctag ttactatgcc cagccttctt ttgttttact
     4861 gacctaggat ctctatagcc caggctgggt ttcagtccac agcgatcaga tcctttctca
     4921 accacctaag agctgaggtg acaggcacac catcacgtgt ggcacttttg tgggtgtgtg
     4981 atggcaaatc tcccacaccc atgtgtccag acgtgagaca gcagagtaga gtgtactgga
     5041 tgctgctgta tccctctcct ccatctctca gggagacaga caaccttctg cccggaccaa
     5101 gatgctgcca tgttttctaa cccagagcct gtctttacta aaaccctctc agcagacctc
     5161 agtaaatctc ctgcctcaga tcccggaatt c
//