From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens TCR V-beta 6.1 gene for TCR beta chain variable region
Date: 29 Aug 92 10:01:52 GMT
Distribution: bionet
Checksum: 25533     4

LOCUS       HUMTRVB61    1080 bp ds-DNA             PRI       29-AUG-1992
DEFINITION  H.sapiens TCR V-beta 6.1 gene for TCR beta chain variable region
ACCESSION   X61440
KEYWORDS    T-cell receptor; T-cell receptor beta-chain variable region;
            TCR V-beta 6.1 gene.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1080)
  AUTHORS   Li,Y., Szabo,P. and Posnett,D.N.
  TITLE     Human Tcr V beta 6.10 is a pseudogene with Alu repetitive sequences
            in the promoter region
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
COMMENT     *source: tissue=placental; *source: clone_library=human genomic
            library; *source: clone=3, 9, 13; *source: isolate=human genomic
            library, Clontech labs., CAT# *source: HL1067J; *source:
            chromosome=7; *source: is_germline=Y;
            From EMBL    entry HSTRVB61;  dated 30-OCT-1991.
FEATURES             Location/Qualifiers
     CDS             join(581..629,740..1037)
                     /partial
                     /gene="TCRB"
                     /codon_start=1
                     /translation="MGTRLLCWAALCLLGADHTGAGVSQTPSNKVTEKGKYVELRCDP
                     ISGHTALYWYRQSLGQGPEFLIYFQGTGAADDSGLPNDRFFAVRPEGSVSTLKIQRTE
                     RGDSAVYLCASSLT"
                     /partial
     promoter        1..580
                     /gene="TCRB"
     exon            581..629
                     /number=1
                     /note="first leader"
                     /gene="TCRB"
     intron          630..739
                     /number=1
                     /gene="TCRB"
     exon            740..1037
                     /number=2
                     /note="second leader and V region"
                     /gene="TCRB"
BASE COUNT      251 a    261 c    306 g    262 t
ORIGIN
        1 ctatagtttc cataaggtat cttttctgaa ttatagtcaa caaaggtgga agtggtccca
       61 ggaaggaaag gcatgaggtg cagcttgtga gggaacccat gtggttggga cagcccgttg
      121 ggcacgtgtg actgggggat ggaggaggct ggggcatcaa tggggatggc ataggggacc
      181 cctgacttgc agaaaagaca atgagctcat cccttggtgc cttgtgttgg gggcgctgtt
      241 ggcacatcct agagaacatg cccagcagac agaggagcgc ctgtgtggtg aggagataaa
      301 ctcagaaatg cagcatgagg cctgtagctc cagacagctc tagagcacaa agtgaagacc
      361 gatgcattga tgttgtttaa aaggagctaa taaatatcta aagcagtcat ccaagtgtgt
      421 tctaatataa atcctgtgtt cctgaggttg tggggattga gagaggaagt gatgtcactg
      481 tgggtactgt tgtgtgtcag gacaaggacg tccctcctcc tctgctcctg ctcacagtga
      541 ccctgatctg gtaaagctcc catcctgccc tgactctgtc atgggcacca ggctcctctg
      601 ctgggcagcc ctgtgcctcc tgggggcagg tgagtcctca gacaccaacc agtctcattc
      661 tgtgtgtctg tatgtgtgtg tgtgtgtgtg atgagtacaa ctgttttcct catcctgttc
      721 tcaacttgtg tctccgcaga tcacacaggt gctggagtct cccagacccc cagtaacaag
      781 gtcacagaga agggaaaata tgtagagctc aggtgtgatc caatttcagg tcatactgcc
      841 ctttactggt accgacaaag cctggggcag ggcccagagt ttctaattta cttccaaggc
      901 acgggtgcgg cagatgactc agggctgccc aacgatcggt tctttgcagt caggcctgag
      961 ggatccgtct ctactctgaa gatccagcgc acagagcggg gggactcagc cgtgtatctc
     1021 tgtgccagca gcttaaccac agcatgacac aatcgcctcc ttcctgctca taaacctcct
//