From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human proteolipid protein (PLP) gene, exon 1.
Date: 31 Jul 92 10:01:30 GMT
Distribution: bionet
Checksum: 54840     3

LOCUS       HUMPLP        397 bp ds-DNA             PRI       31-JUL-1992
DEFINITION  Human proteolipid protein (PLP) gene, exon 1.
ACCESSION   M95057
KEYWORDS    myelin proteolipid protein; proteolipid protein.
SOURCE      Homo sapiens (library: EMBL3 lambda-52) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Diehl,H.-J., Schaich,M., Budzinski,R.-M. and Stoffel,W.
  TITLE     Individual exons encode the integral membrane domains of human
            myelin proteolipid protein
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 83, 9807-9811 (1986)
  STANDARD  full staff_review
REFERENCE   2  (bases 1 to 397)
  AUTHORS   Berndt,J., Kim,J.G. and Hudson,L.D.
  TITLE     Identification of CIS-regulatory elements in the myelin proteolipid
            protein (PLP) gene
  JOURNAL   J. Biol. Chem. 267, 14730-14737 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     protein_bind    40..65
                     /bound_moiety="unspecified"
                     /note="fourth"
                     /gene="PLP"
                     /evidence=EXPERIMENTAL
                     /partial
     protein_bind    67..99
                     /bound_moiety="unspecified"
                     /note="fifth"
                     /gene="PLP"
                     /evidence=EXPERIMENTAL
                     /partial
     protein_bind    186..209
                     /bound_moiety="unspecified"
                     /note="third"
                     /gene="PLP"
                     /evidence=EXPERIMENTAL
                     /partial
     misc_feature    232..275
                     /note="purine-rich stretch"
                     /gene="PLP"
                     /note="putative"
     protein_bind    236..264
                     /bound_moiety="unspecified"
                     /note="second"
                     /gene="PLP"
                     /evidence=EXPERIMENTAL
                     /partial
     TATA_signal     289..292
                     /gene="PLP"
     protein_bind    293..315
                     /bound_moiety="unspecified"
                     /note="first"
                     /gene="PLP"
                     /evidence=EXPERIMENTAL
                     /partial
     exon            313..>397
                     /number=1
                     /gene="PLP"
BASE COUNT      141 a     71 c    116 g     69 t
ORIGIN
        1 gcttgtgctg catatcccac accaattaga cccaaggatc agttggaagt ttccaggaca
       61 tcttcatttt atttccaccc tcaatccaca tttccagatg tctctgcagc aaagcgaaat
      121 tccaggcaag ccttagggaa aaaaggaaaa acaaagaaaa tgaaacaatt ggcagtgaaa
      181 ggcagaaaga gaagatggag cccttagaga agggagtatc cctgagtagg tggggaaaag
      241 gggaggagaa ggggaggagg agaggaggag gaaagcaggc ctgtcccttt aagggggttg
      301 gctgtcaatc agaaagccct tttcattgca ggagaagagg acaaagatac tcagagagaa
      361 aaagtaaaag accgaagaag gaggctggag agaccag
//