From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: T.brucei gene for variant surface glycoprotein
Date: 15 Aug 92 10:03:28 GMT
Distribution: bionet
Checksum: 46801     6

LOCUS       TRBVSGLYP    2874 bp ds-DNA             INV       15-AUG-1992
DEFINITION  T.brucei gene for variant surface glycoprotein
ACCESSION   Z11674
KEYWORDS    surface glycoprotein.
SOURCE      Trypanosoma brucei DNA.
  ORGANISM  Trypanosoma brucei
            Eukaryota; Animalia; Protozoa; Sarcomastigophora; Mastigophora;
            Kinetoplastida; Trypanosomatina; Trypanosomatidae.
REFERENCE   1  (bases 1 to 2874)
  AUTHORS   Beals,T.P.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 2874)
  AUTHORS   Beals,T.P. and Boothroyd,J.C.
  TITLE     Sequence Divergence Among Members of a Trypanosome Variant Surface
            Glycoprotein Gene Family
  JOURNAL   J. Mol. Biol. 225, 973-983 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=Mitat 1.5;
            From EMBL    entry TBVSGLYP;  dated 03-AUG-1992.
FEATURES             Location/Qualifiers
     CDS             1234..2820
                     /product="variant surface glycoprotein"
                     /codon_start=1
                     /translation="MDCQNRAAIALVKWKAATAASVALLYVAVTASGSYEALEYTTWS
                     THCGLAATPRKVHGGILAKLESQITYRNKLEEMEAKLRIYGLKRAGGDEQTTVDMLAS
                     TAALMRMASLKEEKTNMQTALIAVGFASEGAAAVSSYLMTIGSLTHNTQTYCLSNTAK
                     SGNGKAELSTAGCRHGKTSDYKAGIGPDEQEVDASGFTKITGKTGAANTGETSKCGLF
                     THQGNPESAAGIFITAASSKPSFGYGMLKISAQDQTAAQKLSDIKGKTEDDDQTFWSS
                     CHAAVKAGQDMQAEPPLKVDQTLLTVLVASTEMQYILKLEAEASEQKGPEEVTIDLAS
                     AKKTYFGSDNNKLEPPWTKIKGENVVDLTKAKGSTKELGTVTDTTELHKLLSYYYTVR
                     KEKQKKTAEQVEKLETELAAQKGKSPEAECNKIFEEPKCNEDKICSWHKDVKAGEENC
                     QFNSTKAKEKGVSVTQTQTVGGTETTTDKCKGKGEKDCKSPDWKWEGETCKGSSFLVT
                     KVLAVIFCCFYGFDSILNFF"
     sig_peptide     1234..1332
     mat_peptide     1333..2817
                     /product="variant surface glycoprotein"
BASE COUNT     1043 a    617 c    645 g    569 t
ORIGIN
        1 aatgatgcac actgacgcag gatttgtgga gcatagaaag aagctacaca ataaaaacat
       61 gcatacatga tcgcaggtgc agaacgagag acgaattatc tcgacaataa agaagaatag
      121 atctatgaaa tgctcaaagt catgcgtacg agcgaacaag cagcgttata tcgtcatctc
      181 ataaacatcc acgaaacaga agttatagtg tagtagaagc aatgaaagac tctaaatgac
      241 agatgtgata tatacagcaa actggcttgg aatcaaaatt gtaattttca tggataaact
      301 gagtgctttt tacaatatta caacgaccgg agtcgcctat aacagctaaa aactcataac
      361 gttcaaggtc gactatccta acgactgtat gtctaaatgc agaatttaga agaagaaaaa
      421 gaagaaggtt gttaacaaat aaaaagaaag caaaaagtta gaggacgcac gtttttctca
      481 aaacttgcgc ttttagagca gtattgattc tgattaaaca aggttttgca ttataagata
      541 cgacttttta atgtcaaact gcacttaaag gaggcttagc acataaatca attgcagaag
      601 cgtactttcg acatccaatt atttccagaa aacagtaaaa cgttttttgg tgtgtcgcga
      661 cagcaacaag aaaaacttta ctaggaagca gcgtgttaaa tttattttcg atacagcaaa
      721 cgacttcttt cgattcaaaa tgagaaaaaa tacctcaaag caggcatttt cctttaccac
      781 taaacagcgg agcagcaaaa taattaaaac gtttttctta tcaccaaccg tatggcggca
      841 agaggatcga agcggctcgg tattttacat ttttttgcag aaaacaggct gtatggcgga
      901 ctaaaaccgt cagcagacga gtgttcttaa tcggaacaga aaacgaacct ggcgaaccga
      961 aggcataact tgtcctcata cctcctctgg gaatgtaacc aatccgaaca agtacaacca
     1021 ggtcaataaa ctctacattt cgtaaaagag gccagcgcgc cagaagctaa gcaggagcac
     1081 ctccgcaaac aaagccggat gacgcaaggc acggacacgt atttgacatt caccccgaac
     1141 atccacctcc aacataagca gcaaaagact agaagcaacc aacacatata ccaaagagaa
     1201 acggggtttc aacaaaaacg aatacgctcg cgaatggatt gccagaaccg cgcagcaata
     1261 gcactggtaa agtggaaagc agccacagca gcgtcagtgg cgttgctcta cgtggccgtg
     1321 acagcatcag gaagctacga agccctcgaa tacacaactt ggtcaaccca ctgcggtcta
     1381 gcggcgaccc cgagaaaggt acacggaggc atattagcga aactggaaag tcaaattacg
     1441 taccgcaaca aactggaaga aatggaggca aagctacgaa tctacggact aaaaagagca
     1501 ggaggcgacg agcagactac agtcgatatg ctagcatcaa ccgcagcgct catgcgaatg
     1561 gctagcctca aagaagaaaa aaccaatatg caaaccgcgc ttatagccgt gggctttgcg
     1621 agcgaaggag cggctgcggt cagcagctac ctcatgacga tcggttcgct gacccacaac
     1681 acacagacgt actgcttatc taatacagca aaatctggca acgggaaagc agagctatca
     1741 acagccggct gccggcatgg aaaaacaagc gactacaagg ctggaatagg gccagatgag
     1801 caggaagtgg acgccagcgg cttcacaaaa ataactggga aaactggcgc agcaaacacc
     1861 ggggagacgt cgaagtgcgg cttattcacc catcaaggca acccagaatc agcagccggc
     1921 attttcatca cagcggcaag ctccaagcct tccttcggat acggaatgct gaagattagc
     1981 gcacaggacc aaaccgctgc acaaaagctg tcagacataa aaggaaaaac tgaagacgac
     2041 gaccagacat tctggagcag ctgccacgcc gcagtcaagg ccgggcaaga tatgcaggca
     2101 gaaccacccc taaaagtcga ccaaacactc ctaactgttc ttgtggcgtc gacagagatg
     2161 cagtacatac tgaaactaga agcggaagca tcagagcaaa aaggaccaga ggaagtaacg
     2221 atcgacctag ccagcgccaa aaaaacttat ttcggcagcg acaacaacaa actagagccg
     2281 ccctggacta aaatcaaagg agagaatgta gttgacctga ccaaggccaa aggtagcacg
     2341 aaagagttag gaacggtcac agacacgacc gagctccata aacttttaag ttattattac
     2401 acggtcagaa aagaaaagca gaaaaaaaca gcggagcagg tagaaaaact agaaaccgaa
     2461 ctagcagctc aaaaaggcaa atcccctgaa gcagaatgca ataaaatatt tgaggaaccc
     2521 aaatgcaacg aggacaagat ttgcagttgg cataaggatg ttaaagcggg agaagagaac
     2581 tgccaattta actcaacaaa agcaaaagaa aaaggggttt ctgtaacaca aactcaaact
     2641 gtaggaggaa cagaaacaac aacagataag tgtaaaggga aaggagagaa agactgcaaa
     2701 tctccggatt ggaaatggga gggtgaaact tgcaagggtt ccagttttct tgtcactaaa
     2761 gtattggctg taattttctg ctgcttttat gggtttgata gcattttaaa ttttttctaa
     2821 ttgagcataa tttgaaaatt tactaaagtt tgaaatattt taacacttta tgaa
//