From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus PD-1 mRNA
Date: 28 Dec 92 21:30:35 GMT
Distribution: bionet
Checksum: 04063 5

LOCUS       MUSPD1MR     1973 bp ss-RNA             ROD       01-DEC-1992
DEFINITION  M.musculus PD-1 mRNA
ACCESSION   X67914
KEYWORDS    immunoglobulin superfamily.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1973)
  AUTHORS   Ishida,Y., Agata,Y., Shibahara,K. and Honjo,T.
  TITLE     Induced expression of PD-1 a novel member of the immunoglobulin
            gene superfamily upon programmed cell death
  JOURNAL   EMBO J. 11, 3887-3895 (1992)
  STANDARD  full automatic
COMMENT     *source: cell_line=2B4.11; *source: clone_library=lambda gt10;
            *source: clone=7;
               From EMBL    entry MMPD1MR;  dated 21-OCT-1992.
FEATURES             Location/Qualifiers
     sig_peptide     64..123
     misc_feature    124..564
                     /note="extracellular domain"
     misc_feature    565..645
                     /note="transmembrane domain"
     misc_feature    646..927
                     /note="cytoplasmic domain"
     CDS             64..930
                     /gene="PD-1"
                     /codon_start=1
                     /translation="MWVRQVPWSFTWAVLQLSWQSGWLLEVPNGPWRSLTFYPAWLTV
                     SEGANATFTCSLSNWSEDLMLNWNRLSPSNQTEKQAAFCNGLSQPVQDARFQIIQLPN
                     RHDFHMNILDTRRNDSGIYLCGAISLHPKAKIEESPGAELVVTERILETSTRYPSPSP
                     KPEGRFQGMVIGIMSALVGIPVLLLLAWALAVFCSTSMSEARGAGSKDDTLKEEPSAA
                     PVPSVAYEELDFQGREKTPELPTACVHTEYATIVFTEGLGASAMGRRGSADGLQGPRP
                     PRHEDGHCSWPL"
BASE COUNT      510 a    524 c    531 g    408 t
ORIGIN      
        1 tgagcagcgg ggaggaggaa gaggagactg ctactgaagg cgacactgcc aggggctctg
       61 ggcatgtggg tccggcaggt accctggtca ttcacttggg ctgtgctgca gttgagctgg
      121 caatcagggt ggcttctaga ggtccccaat gggccctgga ggtccctcac cttctaccca
      181 gcctggctca cagtgtcaga gggagcaaat gccaccttca cctgcagctt gtccaactgg
      241 tcggaggatc ttatgctgaa ctggaaccgc ctgagtccca gcaaccagac tgaaaaacag
      301 gccgccttct gtaatggttt gagccaaccc gtccaggatg cccgcttcca gatcatacag
      361 ctgcccaaca ggcatgactt ccacatgaac atccttgaca cacggcgcaa tgacagtggc
      421 atctacctct gtggggccat ctccctgcac cccaaggcaa aaatcgagga gagccctgga
      481 gcagagctcg tggtaacaga gagaatcctg gagacctcaa caagatatcc cagcccctcg
      541 cccaaaccag aaggccggtt tcaaggcatg gtcattggta tcatgagtgc cctagtgggt
      601 atccctgtat tgctgctgct ggcctgggcc ctagctgtct tctgctcaac aagtatgtca
      661 gaggccagag gagctggaag caaggacgac actctgaagg aggagccttc agcagcacct
      721 gtccctagtg tggcctatga ggagctggac ttccagggac gagagaagac accagagctc
      781 cctaccgcct gtgtgcacac agaatatgcc accattgtct tcactgaagg gctgggtgcc
      841 tcggccatgg gacgtagggg ctcagctgat ggcctgcagg gtcctcggcc tccaagacat
      901 gaggatggac attgttcttg gcctctttga ccagattctt cagccattag catgctgcag
      961 accctccaca gagagcaccg gtccgtccct cagtcaagag gagcatgcag gctacagttc
     1021 agccaaggct cccagggtct gagctagctg gagtgacagc ccagcgcctg caccaattcc
     1081 agcacatgca ctgttgagtg agagctcact tcaggtttac cacaagctgg gagcagcagg
     1141 cttcccggtt tcctattgtc acaaggtgca gagctggggc ctaagcctat gtctcctgaa
     1201 tcctactgtt gggcacttct agggacttga gacactatag ccaatggcct ctgtgggttc
     1261 tgtgcctgga aatggagaga tctgagtaca gcctgctttg aatggccctg tgaggcaacc
     1321 ccaaagcaag ggggtccagg tatactatgg gcccagcacc taaagccacc cttgggagat
     1381 gatactcagg tgggaaattc gtagactggg ggactgaacc aatcccaaga tctggaaaag
     1441 ttttgatgaa gacttgaaaa gctcctagct tcgggggtct gggaagcatg agcacttacc
     1501 aggcaaaagc tccgtgagcg tatctgctgt ccttctgcat gcccaggtac ctcagttttt
     1561 ttcaacagca aggaaactag ggcaataaag ggaaccagca gagctagagc cacccacaca
     1621 tccagggggg cacttgactc tccctactcc tcctaggaac caaaaggaca aagtccatgt
     1681 tgacagcagg gaaggaaagg gggatataac cttgacgcaa accaacactg gggtgttaga
     1741 atctcctcat tcactctgtc ctggagttgg gttctggctc tccttcacac ctaggactct
     1801 gaaatgagca agcacttcag acagtcaggg tagcaagagt ctagctgtct ggtgggcacc
     1861 caaaatgacc agggcttaag tccctttcct ttggtttaag cccgttataa ttaaatggta
     1921 ccaaaagctt taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//