From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse GABA-A receptor alpha-1 subunit mRNA, complete cds.
Date: 31 Dec 92 01:38:07 GMT
Distribution: bionet
Checksum: 41965 6

LOCUS       MUSGABA1A    1728 bp ss-mRNA            ROD       17-DEC-1992
DEFINITION  Mouse GABA-A receptor alpha-1 subunit mRNA, complete cds.
ACCESSION   M86566 M57519
KEYWORDS    GABA-A receptor alpha-1 subunit.
SOURCE      Mus musculus (strain C57BL/6J, sub_species domesticus) adult brain
            cDNA to mRNA; and Mus musculus (strain DBA/2J) adult brain cDNA to
            mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1728)
  AUTHORS   Wang,J.B., Kofuji,P., Fernando,J.C., Moss,S.J., Huganir,R.L. and
            Burt,D.R.
  TITLE     The alpha 1, alpha 2, and alpha 3 subunits of GABAA receptors:
            comparison in seizure-prone and -resistant mice and during
            development
  JOURNAL   J. Mol. Neurosci. 3, 177-184 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     149..289
                     /gene="GABA-A receptor alpha-1 subunit"
                     /codon_start=1
     mat_peptide     290..1513
                     /product="GABA-A receptor alpha-1 subunit"
                     /gene="GABA-A receptor alpha-1 subunit"
                     /codon_start=1
     allele          770
                     /type="strain DBA/2J"
                     /gene="GABA-A receptor alpha-1 subunit"
                     /note="replace (770..g)"
     allele          926
                     /type="strain DBA/2J"
                     /gene="GABA-A receptor alpha-1 subunit"
                     /note="creates NsiI site; replace (926..a)"
     allele          1055
                     /type="strain DBA/2J"
                     /gene="GABA-A receptor alpha-1 subunit"
                     /note="replace (1055..t)"
     allele          1061
                     /type="strain DBA/2J"
                     /gene="GABA-A receptor alpha-1 subunit"
                     /note="replace (1061..t)"
     allele          1706
                     /type="strain DBA/2J"
                     /gene="GABA-A receptor alpha-1 subunit"
                     /note="replace (1706..g)"
     CDS             149..1516
                     /gene="GABA-A receptor alpha-1 subunit"
                     /product="GABA-A receptor alpha-1 subunit"
                     /codon_start=1
                     /translation="MKKSRGLSDYLWAWTLILSTLSGRSYGQPSQDELKDNTTVFTRI
                     LDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLK
                     FKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLT
                     VRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYD
                     LLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE
                     SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
                     YFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSA
                     TIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKA
                     PTPHQ"
BASE COUNT      478 a    433 c    394 g    423 t
ORIGIN      
        1 gagcgcggcg cgaggacgcc ctccgcccgg cgcgcccgcg tcgcagactc gcgcacgtcc
       61 gactcaccgc gatcctctct cccacacttt tctcccgggt ctggagcgat ccggtgccca
      121 gaggggcccc gagctgtgca agcccgtgat gaagaaaagt cggggtctct ctgactatct
      181 ttgggcctgg accctcattc tgagcacact gtcgggaaga agctatggac agccctccca
      241 agatgaactt aaagacaaca ccactgtctt cacaagaatt ttggaccgac tgctggacgg
      301 ttatgacaat cgtctgagac caggtttggg agagcgtgta actgaagtga agaccgacat
      361 tttcgtcacc agtttcggac cagtttcaga ccacgatatg gagtatacaa tagatgtgtt
      421 tttccgtcaa agttggaagg atgaaagatt aaaattcaaa ggacccatga cagtgctccg
      481 gctaaacaac cttatggcca gtaaaatctg gactccagat acatttttcc acaatggaaa
      541 gaagtctgtg gcccacaaca tgaccatgcc taataagctc ctgcgtatca cagaggatgg
      601 cactctgctg tacaccatga ggttgaccgt gagagctgaa tgcccaatgc acttggaaga
      661 cttccctatg gatgcccatg cctgcccact aaaattcgga agctatgctt atacaagagc
      721 agaagttgtc tatgagtgga ccagagagcc agcccgttca gtggttgtag cagaagatgg
      781 gtcacgttta aaccagtatg accttcttgg acaaacagtt gactctggaa ttgttcagtc
      841 cagtactgga gaatatgtgg ttatgacgac tcacttccac ttgaagagaa aaattggcta
      901 ctttgttatt caaacatatc tgccgtgcat aatgacagtt attctctccc aagtctcctt
      961 ctggctcaac agagagtcag taccagcaag aactgtcttt ggagtgacga ctgttctgac
     1021 tatgacaacc ttgagtatca gtgccagaaa ttccctcccg aaggtggctt atgcaacagc
     1081 tatggactgg tttattgcag tatgctatgc ctttgttttc tcagctctga ttgagtttgc
     1141 cacagtaaac tatttcacca agagagggta tgcgtgggat ggcaaaagcg tggttccaga
     1201 aaagccaaag aaagtaaagg atcctctcat taagaaaaac aacacatatg ctcctacagc
     1261 aaccagctat acccctaact tagccagggg tgaccccggc ttggcaacta ttgctaaaag
     1321 tgcgaccata gaaccgaaag aagtcaagcc tgagacaaaa ccaccagaac ccaagaaaac
     1381 ctttaacagc gtcagcaaaa tcgaccgact gtcaagaata gcctttccgc tgctatttgg
     1441 aatctttaac ttagtctatt gggccacgta tttaaacaga gagcctcagc taaaagcccc
     1501 cacaccccat caataggttc ttttagtcgt attctgttgt tcagtcctct gcaccgagaa
     1561 ttgctttctg ttctcaacgc agtgattcct atctgcttta ctgcctctgt cctaaagaat
     1621 ttgaaggttt ccttatttcc atatttcata caagaacaag agacccctgt ctgacagtcc
     1681 agagcagagc agagtattca gctcagggac aggattctga gaggagca
//