From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: CYP2B12=cytochrome P-450 [rats, mRNA, 2529 nt]
Date: 22 Jan 93 19:51:14 GMT
Distribution: bionet
Checksum: 39696 6

LOCUS       S117647      2529 bp    mRNA            ROD       21-JAN-1993
DEFINITION  CYP2B12=cytochrome P-450 [rats, mRNA, 2529 nt]
ACCESSION   S48369 X63545
KEYWORDS    .
SOURCE      rats
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 2529)
  AUTHORS   Friedberg,T., Grassow,M.A., Bartlomowicz-Oesch,B., Siegert,P.,
            Arand,M., Adesnik,M. and Oesch,F.
  TITLE     Sequence of a novel cytochrome CYP2B cDNA coding for a protein
            which is expressed in a sebaceous gland, but not in the liver.
  JOURNAL   Biochem. J. 287 ( Pt 3), 775-783 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 117647] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 3.
FEATURES             Location/Qualifiers
     CDS             40..1518
                     /note="mismatches(28[R->H],83[G->D]).  For the protein
                     sequence (NCBI gibbsq 117648):  Method: conceptual
                     translation supplied by author.  This sequence comes from
                     Fig. 4.
                     Author-given protein sequence is in conflict with the
                     conceptual translation"
                     /gene="CYP2B12"
                     /product="cytochrome P-450"
                     /codon_start=1
                     /translation="MEFGVLLLLTLTVGFLLFLVSQSQPKTRGHLPPGPRPLPFLGNL
                     LQMNRRGFLNSFMQLQEKYGDVFTVHLGPRPVVILCGTGTIREALVDQAEAFSGRGTV
                     AVLHPVVQGYGVIFATGERWKTLRRFSLVTMKEFGMGKRSVDERIKEEAQCLVEELKK
                     YKGAPLNPTFLFQSIAANTICSIVFGERFDYKDHQFLHLLDLVYKTSVLMGSLSSQVF
                     ELYSGFLKYFPGAHKQIFKNLQEMLNYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKE
                     KSNHHTEFNHQNLVISVLSLFFAGTETTSTTLRCTFLIMLKYPHVAEKVQKEIDQVIG
                     SHRLPTPDDRTKMPYTDAVIHEIQRFADLTPIGLPHRVTKDTVFRGYLLPKNTEVYPI
                     LSSALHDPRYFEQPDTFNPEHFLDANGALKKSEAFLPFSTGKRICLGEGIARNELFIF
                     FTAILQNFTLASPVAPEDIDLTPINIGVGKIPSPYQINFLSR"
BASE COUNT      662 a    683 c    521 g    663 t
ORIGIN      
        1 ggagtgttca ctgaagtcaa cagtggttag accaggacca tggaattcgg tgtcttgctc
       61 ctcctcactc tcactgtggg cttcttgcta ttcttagtca gccaaagtca gccaaagacc
      121 catgggcact tgccaccagg acctcgtccc ctgcccttct tggggaacct cttacagatg
      181 aacagaagag gctttctgaa ttctttcatg cagcttcaag aaaaatatgg agatgtgttc
      241 acagtacacc tgggaccaag gcccgtggtc atattgtgtg ggacagacac cataagagag
      301 gctctggtgg accaagctga agctttctct ggtcggggaa cagttgctgt gctccatcca
      361 gttgtacagg gatatggtgt gatctttgcc actggggaac gttggaagac ccttcggcga
      421 ttctctctgg tcaccatgaa agaattcgga atgggaaagc ggagtgtaga tgagaggata
      481 aaggaggagg cccagtgttt ggtggaggag ctgaagaaat acaagggagc ccccctgaac
      541 cccaccttcc tcttccaatc catcgcagca aacaccatct gctccattgt ctttggagag
      601 cgctttgact acaaagacca ccagttcctg catctgctgg atctagtcta taagacatct
      661 gtccttatgg gctccttgtc cagccaggtg tttgagcttt actctggctt cctgaaatac
      721 tttcctggtg cccacaaaca aatcttcaaa aacctacagg aaatgctcaa ctacattggc
      781 catattgtgg agaagcacag ggcaaccttg gaccccagtg ctccacgaga tttcatcgat
      841 acttaccttc tgcgcatgga gaaggagaag tccaaccatc acacagagtt caatcaccag
      901 aaccttgtga tctctgtgct ctctctcttc tttgctggca ccgagaccac cagcaccacg
      961 ctccgttgca ccttcctgat catgctcaag tacccccacg ttgcagagaa agtccaaaag
     1021 gagattgatc aggtgattgg ctcacaccgg ctaccaaccc ctgatgatcg taccaaaatg
     1081 ccatatactg atgcagtcat ccatgagatt cagagatttg cagatctgac cccgattggt
     1141 ctaccacaca gagtcaccaa agacaccgtg ttccgagggt acctgcttcc caagaacact
     1201 gaggtgtacc ccatcctgag ttcagctctc catgacccac ggtactttga acaaccagac
     1261 actttcaatc ctgagcactt cctggatgcc aatggggcac tgaagaagag tgaagctttt
     1321 ctgcccttct ctacaggaaa gcgcatttgt cttggagaag gcattgcccg aaatgaattg
     1381 ttcattttct tcaccgccat cctgcagaac ttcactttgg caagccctgt ggctcctgag
     1441 gacattgacc tcactcccat taacattggt gtaggcaaaa taccctctcc ataccagata
     1501 aacttcctgt cccgttgaat aggttgagag agaagagtca atggaatgac gtgtccccat
     1561 tgccgtaccc tatgaatgga atagtaaaac ctaatgaagt ggctttcttg ttacatagac
     1621 agagagactt ctggaggcca cagcttgttg tgagacacct ctctcatgct tgttcacagc
     1681 catagtccct acttgttagg aatctagact ccaggatctg tgggaacaga ccagagatgg
     1741 tttctcttga gttggctcca ttctaatccc atgtggtgtg ttggggggtc atgtttgagg
     1801 acccccttcg tagatgagta acagacccta tgatggcatc acagtgctag tgagtagtgg
     1861 ggaacaaaat tatgctgtga gtctagaaga gcaaccccct ctcctgcttc tgtttcaatt
     1921 cagatgaaat tcatataacg aagctgacaa aatcttttaa ttttgtattc aggccagagg
     1981 ctcatgtagt tcacactgac ctcaaaatcc tatatacatc caaagatgtc ttgaaatctc
     2041 gatctcctga ccagtgctgg catcacagcc acatggacgt atacccagat tttaaagtga
     2101 ctatatcata atgtttatat tttaatctcc tttaatttat ttgcaatatt acaacttcac
     2161 tatctaattc caggtatttt gtcacactta accaacacca cccaaaagcc ccaacctatt
     2221 caaagatcaa tccctcatcc cctctctcca taacctcccc tgcactcaac acccaccgtg
     2281 ccacttttgt cacacttaac caacaccacc aaaagcccca acctattcaa agatcaatcc
     2341 ctcatcccct ctctccataa cctcccctgc actcaacacc caccgtgcca cttttgtctg
     2401 acttttgtgt cattggactg tcctgaattg tgtgtctcat agaaaaacaa cgacatgatg
     2461 tttaatgctg gctgactttt atgccacacc caacttctca ggcccctgac tgtggcctgc
     2521 acagtacag
//