HDTenEightyP/NetNews huggingface dataset:
From: robison1@husc10.harvard.edu (Keith Robison)
Newsgroups: sci.chem,sci.bio
Subject: Re: Left-handed sugar
Date: 30 Dec 92 14:09:00 GMT
 <72463@cup.portal.com> <1992Dec27.211004.24998@nntpd2.cxo.dec.com>   
 <dexter.725570507@aries> <1992Dec28.231101.13255@nntpd2.cxo.dec.com> <dexter.725655833@aries>

While browsing through SwissProt (a protein database) using the NIH's
Gopher server (gopher.nih.gov) I found the following genes
of interest to this discussion:

organisms:      Escherichia coli and Salmonella typhimurium
		(enteric gram-negative eubacteria)
gene name:	araD 
enzyme:		L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
reaction:	L-ribulose-5-phosphate <-> D-xylose 5-phosphate
pathway:	3rd step of L-arabinose catabolism

		Note that this enzyme both converts D<->L and ketose<->aldose


organisms:	Kluyvermyces lactis and Saccharmyces carlsbergensis 
		(yeasts)
gene name:	galX 
organisms:	Acinetobacter calcoacticus and Streptococcus thermophilus
		(eubacteria)
gene name:	murO
enzyme:		aldose 1-epimerase (EC 5.1.3.3)
reaction:	alpha-D-glucose <-> beta-D-glucose
		also acts on: 
			L-arabinose, 
			D-xylose, D-galactose, maltose, lactose
pathway:	galactose metabolism




Keith Robison
Harvard University
Department of Cellular & Developmental Biology
Department of Genetics / HHMI

robison@biosun.harvard.edu 
Newsgroups: sci.chem,sci.environment
From: bjgaed@bb1t.monsanto.com
Subject: Re: Alternative refrigerants
Organization: Monsanto Company, St. Louis, MO
Date: Tue, 22 Dec 1992 13:41:45 GMT

In article <72070@cup.portal.com>, mmm@cup.portal.com (Mark Robert Thorson) writes:
> With regard to refrigerants and alternatives to fluorocarbons, there
> are many alternatives, though none combine the low flammability,
> low toxicity, and chemical inertness of the various fluorocarbon products
> (such as Freon).
> 
[Discussion of alternative refrigerants deleted]

At the Organic Reactions Catalysis Society meeting last spring a paper 
was presented by Leo Manzer of DuPont on their work on developing an 
alternative to chlorofluorocarbon refrigerants.  Interest centers on 
HFC-134a, CF3CFH2.  Contains no chlorine.  Targeted for the 1994-1996 
time frame for phaseout of chlorofluorocarbons.

-- 
--Electric Monk            (Bruce Gaede); 
                            e-mail: bjgaed@ccmail.monsanto.com

"...and then time started seriously to pass."
--Douglas Adams, _Dirk Gently's Holistic Detective Agency_
Newsgroups: sci.chem
From: ns14@crux2.crux2.cit.cornell.edu (Nathan Otto Siemers)
Subject: Re: Organic Chem Experts, please help me with this!
Organization: Department of Chemistry, Cornell Univ.
	<NS14.92Dec28020829@crux2.crux2.cit.cornell.edu>
	<1992Dec29.175030.14037@ux1.cts.eiu.edu>
Date: 2 Jan 93 23:14:55

>>>>> On Tue, 29 Dec 1992 17:50:30 GMT, cfthb@ux1.cts.eiu.edu (Howard Black) said:

 Howard> In article <NS14.92Dec28020829@crux2.crux2.cit.cornell.edu> ns14@crux2.crux2.cit.cornell.edu (Nathan Otto Siemers) writes:
>
>	These are esters of phthalic acid, which I think are benzene
>rings with two carboxylic acids attached to the ring.  They are often
>ortho, but need not be so.

 Howard> If they're not ortho, it's not phthalic acid.

	The post was patronizing as it is, but I did answer it.

	1,3 benzenedicarboxylic acid is known as m-phthalic acid


	Terephthalic acid is the para, known also as p-phthalic acid.

	[Merck Index]

	Nathan
--
--
/  | / /__|  /  /---/ /__| /  | /    nathan@chemres.tn.cornell.edu
From: ebstokes@maxwell.crd.ge.com (Ed Stokes)
Newsgroups: sci.chem
Subject: phthalimide luminescence
Date: 29 Dec 92 22:42:37 GMT
Organization: GE Corp. Research & Development, Schenectady, NY

We are investigating the optical properties of derivatives of
phthalimide:

                         R
                         |
                         CH2
                         |
                         N
                        / \
                     O=C   C=O
                       |  /
                       C=C
                      /   \
                     C     C
                      \\ //
                       C-C

where R in this case is a halogenated biphenyl. In published
data tables (CRC Atlas of Spect. Data and Phys. Const. for
Org. Comp., #p1391), phalimide shows no uv absorption
above 291nm. However, we have observed a luminescence
with excitation/emission maxima at 350/410 nm.

Is anyone aware of previous luminescence work done with
phalimide and its derivatives ?

Ed Stokes
ebstokes@crd.ge.com
Newsgroups: sci.chem,sci.bio
From: dexter@aries.scs.uiuc.edu (The Gecko)
Subject: Re: Left-handed sugar
Organization: University of Illinois at Urbana
Date: Sun, 3 Jan 1993 17:26:26 GMT

winalski@adserv.enet.dec.com (Paul S. Winalski) writes:

>According to my copy of Lehninger (regrettably quite old), the enzyme that
>catalyzes the reaction fructose-1,6-diphosphate <-> DHAP + G-3-P (aldolase?)
>is absolutely specific for dihydroxyactone phosphate, but will accept a
>variety of aldehyde phosphates, or aldoses, in place of G-3-P.  It will take
>glyceraldehyde as well as its 3-phosphate, for example, to give
>fructose-1-phosphate.  This means that for aldolase at least, the configuration
>about carbon 3 of the aldehyde substrate isn't a critical factor.  It very
>well might be that a D-configuration about this carbon is critical, however.
>That's why I asked the question whether D/L specificity had been studied
>for these enzymes (and the related ones of the Calvin cycle and pentose
>phosphate shunt).

	The 3-carbon of glyceraldehyde does not have four different groups
attached and so is not a contributor to chirality of the molecule.  It is
C-2 which is classified as D or L.  Also, DHAP is not chiral, and so enzyme
specificity here is not an issue of stereochemistry.

	Annette
From: treesh@bach.helios.nd.edu (carey treesh)
Newsgroups: sci.chem
Subject: Organic Chem Experts, please help me with this!
Date: 27 Dec 92 16:17:24 GMT
Article-I.D.: news.1992Dec27.161724.22215
Organization: OUC, University of Notre Dame

There are probabaly only a handfull of people out there who know anything
about this, but I will try to find you guys via Internet in sci.chem.

Question 1: In very laymens terms please define: "Phthalic ester solvent"

Question  In very laymens terms please define: "Phenyl Oxolate ester"

Question 3: Can these be purchased in stable liquid forms, or must they
be synthisized in the lab?  Are they toxic, or hazerdous?

Incase your wondering, these indeed are the MAGIC FORMUL FOR GLOW STICKS.
All other chemicals needed are pretty easy to get ahold of.  Really
the only others needed are floursent dye and hydrogen peroxide.

ctfm
 
Newsgroups: sci.chem
From: hinz@picard.med.ge.com (David Hinz Mfg 4-6987 ~BHOSVWZ#097)
Subject: Re: Home Solvent for Silly Putty
Organization: GE Medical Systems, Magnetic Resonance
X-Newsreader: TIN [version 1.1 PL6]
Date: Wed, 30 Dec 92 07:38:49 GMT

buxton (buxton@whitewater.chem.wisc.edu) wrote:
: My niece managed to rub quite a bit of silly putty into our carpeting this  
: Christmas, and I was wondering if anyone had any experience with removing  
: this stuff from carpeting. 
: Eric

In a less-enlightened age, I would have suggested a can of freon to freeze
it, which would enable you to shatter it.  

In this enlightened age we live in (relatively, allegedly), I would suggest
that you get a thermos-bottle full of liquid nitrogen from the chem department
at UW-Madtown, I'm sure someone has some.  Freeze the silly-putty, & shatter it 
with a hammer, that oughta do it.

Standard textile-type product disclaimer:  Test this product in an inconspicuous
area, to make sure it doesn't A> shatter the carpet fibres as well, B> turn them
purple with green splotches, or C> cause cancer in labaratory animals.

Oh, the liquid nitrogen should keep pretty well in the thermos bottle, if it's
a good one, for a while anyway.  And be careful not to freeze your fingers!

--

Dave Hinz  -  Opinions expressed are mine, not my employer's.  Obviously.
Don't blame me; I voted for Perot!                hinzd@picard.med.ge.com 
SAAB - Because you get what you pay for.             Pherrets are Phun!!!
From: vporguen@unlinfo.unl.edu (victor porguen)
Newsgroups: sci.chem
Subject: Re: Potassium Chloride uses?
Date: 1 Jan 1993 04:23:13 GMT
Organization: University of Nebraska--Lincoln	
Distribution: world
NNTP-Posting-Host: unlinfo.unl.edu

minsky@media.mit.edu (Marvin Minsky) writes:


>In article <19473.2b430f45@ecs.umass.edu> rrooks@ecs.umass.edu (Raymond Rooks) writes:

>>
>>   Some strange woman came by the lab today and said that she was wanting to
>>know if we had some KCl.  I am wondering why she might have wanted this salt.
>>
>>   She didn't look like she would have any class related reason for it,
>>espically since classes are over.  Can someone enlighten me as to what she
>>may have needed it for?
>
>Perhaps she is hypertensive, and heard that KCL is a good salt substitute.


No, no!  She was experimenting with lethal-injection formulas,
having heard that potassium chloride will stop the heartbeat
if injected into the bloodstream. 



V.P.


Newsgroups: sci.chem,sci.bio
From: dexter@aries.scs.uiuc.edu (The Gecko)
Subject: Re: Left-handed sugar
Organization: University of Illinois at Urbana
Date: Wed, 30 Dec 1992 18:45:04 GMT

cfthb@ux1.cts.eiu.edu (Howard Black) writes:

>>	I'm pretty sure that the enantiomer of D-glucose is L-idose, ie. that
>>the named designation of a monosaccharide is absolute, rather than relative 
>>to the D/L carbon.  This would make D- and L-glucose epimers at C-5, all the
>>other stereocentres being fixed.

>    "Epimer" is a pretty generic term, and usually refers to a single
>stereocenter.  Thus, a phrase might be "epimeric at C-5".
>    This has no bearing on the contention that D- and L-glucose are
>epimeric only at C-5, which is just wrong.  D- and L-Glucose are
>enantiomers, meaning that all four chiral centers are inverted.  If only
>one stereocenter is changed, you make a diastereomer = different compound
>with a different name.  Look it up.

	Apologies for the error.  I tried to make it clear I wasn't working
from a text, but from memory.  I'm a few thousand miles from any of my texts
at present.

	I think my use of the term "epimer" was clear, and correct.  Epimers
are diastereomers which vary at only one stereocentre.  (Modern usage avoids
the term "chiral centre", as chirality only exists in the three-dimensional
context of the molecule.) 

	Annette
	dexter@aries.scs.uiuc.edu

Newsgroups: sci.chem
From: ns14@crux2.crux2.cit.cornell.edu (Nathan Otto Siemers)
Subject: Re: Organic Chem Experts, please help me with this!
Organization: Department of Chemistry, Cornell Univ.
Date: 28 Dec 92 02:08:29

>>>>> On Sun, 27 Dec 1992 16:17:24 GMT, treesh@bach.helios.nd.edu (carey treesh) said:

 carey> There are probabaly only a handfull of people out there who
 carey> know anything about this, but I will try to find you guys via
 carey> Internet in sci.chem.

 carey> Question 1: In very laymens terms please define: "Phthalic
 carey> ester solvent"

	These are esters of phthalic acid, which I think are benzene
rings with two carboxylic acids attached to the ring.  They are often
ortho, but need not be so.  Your question seems indeterminate;  there
are many "phthalic esters"  Diethyl phthalate,  dioctyl phthalate,
etc, depending on the other part that attaches to the carbonyl.  

 carey> Question In very laymens terms please define: "Phenyl Oxolate
 carey> ester"

	If you mean "phenyl oxalate ester"  this is the phenyl ester
of oxalic acid, which should be:

	ho-co-co-oh   with o-phenyl instead of oh

 carey> Question 3: Can these be purchased in stable liquid forms, or
 carey> must they be synthisized in the lab?  Are they toxic, or
 carey> hazerdous?

	Phthalates are stable and readily available, used as
plasticisers in the polymer industry.




--
--
/  | / /__|  /  /---/ /__| /  | /    nathan@chemres.tn.cornell.edu
From: jef@netcom.com (Jef Poskanzer)
Newsgroups: sci.chem
Subject: All the World's Solvents?
Date: 23 Dec 92 17:15:12 GMT
Reply-To: Jef Poskanzer <jef@netcom.com>
Organization: Paratheo-Anametamystikhood Of Eris Esoteric
X-Face: uPIE),q]+zmF49L%(pdE;nX/8$/J22&&&C@_)8BouYx42Y--?*,\]*MIeTY#mCM(x>FyD@+0D-Jm]S_8lxop(Q-$L#~b8!ha;eF[b+GOLyu<]4$">NeVymJ@F#M?1O`ue4,h4`2S^KGjmP%no(d,:<Ur:+f6W8$J:'t9BxH

Something I've wanted for a long time is a beginners-level list of
the major classes of solvents, along with the types of things they're
good for and what's dangerous about them.  Something like:

    acetone
	Good for nail polish.
	Don't sniff.
    light saturated hydrocarbons (kerosene, gasoline, peanut oil)
	Good for grease (heavy hydrocarbons).
	Good for adhesive tape residue.
	Don't sniff.
    methyl-ethyl-ketone
	Good for ???.
	Don't get on skin.
    chlorine bleach
	May not actually remove contaminants, but makes them colorless.
	Don't mix with ???, gives off chlorine.
    hydrogen peroxide
	Similar to bleach, but doesn't give off chlorine.
    hydrofluoric acid
	Good for etching glass.
	Avoid all contact.

Has anyone ever come across anything like this?  If not maybe we
should create it.  Feel free to post of mail additions / corrections
and I'll post periodic snapshots.
---
Jef

           Jef Poskanzer  jef@netcom.com  jef@well.sf.ca.us
"No man can know, until he experiences it, what it is like to feel his
life's blood drawn away into the veins of the woman he loves." -- Bram
                                Stoker
From: bco100@cd4680fs.rrze.uni-erlangen.de (N. van Eikema Hommes)
Newsgroups: sci.chem
Subject: Re: Chemistry in the Marketplace
Date: 29 Dec 1992 17:23:33 +0100
Organization: Regionales Rechenzentrum Erlangen
NNTP-Posting-Host: cd4680fs.rrze.uni-erlangen.de

BTCL_LTD@db1.cc.rochester.edu (Brian Connell) writes:

>Several months ago I remember a discussion about various chemicals used in the
>household. One of the books mentioned (I believe) was Chemistry in the
>Marketplace. Could someone please tell me the author and possibly the publisher
>of this book?

The author of this (very nice) book is Ben Selinger. It was published by
Harcourt Brace Jovanovich, Publishers, Sidney, London, Orlando, San Diego,
Toronto. The ISBN number (fourth edition) is 0-7295-0334-8.

Best wishes for 1993!

      Nico van Eikema Hommes

+======================================+=====================================+
|  Dr. N.J.R. van Eikema Hommes        |  hommes@organik.uni-erlangen.de     |
|  Institut fuer Organische Chemie I   |  Tel. : 49/0 - 9131 - 85 - 4096     |
|  Henkestr. 42, D-8520  Erlangen, FRG |  Fax  :                  - 9132     |
+======================================+=====================================+
From: douddy@cnsvax.uwec.edu
Newsgroups: sci.chem
Subject: Glow Cubes
Date: 22 Dec 92 19:20:40 GMT
Organization: University of Wisconsin Eau Claire


	Has anyone ever heard of 'Glow Cubes?'  I remember reading somewhere
that they were tritium isotope incased in a acrylic plastic block with trace
Phosporous.  Decay released beta-radiation that stimulated the phosphorous and
emmited light.  The high speed electrons never penetrated the surface of the
acrylic block. The glow cubes were highly portable light sources with no
external power requirements, putting out few watts of light for years.
	I wish I remember were I read this, could of been in Scientific 
American... but it was some time ago that I read this, prob on the order of
3-6 months.

Dustan Doud
DOUDDY@CNSVAX.UWEC.EDU
'It's not like the universe isn't going to run down anyway'  
Newsgroups: sci.chem
From: lachlan@dmp.csiro.au (Lachlan Cranswick)
Subject: Re: Potassium Chloride uses? - Radiation Poisoning?
Organization: CSIRO Division of Mineral Products, Melbourne, AUSTRALIA
Date: Fri, 1 Jan 1993 08:29:30 GMT

vporguen@unlinfo.unl.edu (victor porguen) writes:

>minsky@media.mit.edu (Marvin Minsky) writes:


>>In article <19473.2b430f45@ecs.umass.edu> rrooks@ecs.umass.edu (Raymond Rooks) writes:

>>>
>>>   Some strange woman came by the lab today and said that she was wanting to
>>>know if we had some KCl.  I am wondering why she might have wanted this salt.
>>>
>>>   She didn't look like she would have any class related reason for it,
>>>espically since classes are over.  Can someone enlighten me as to what she
>>>may have needed it for?
>>
>>Perhaps she is hypertensive, and heard that KCL is a good salt substitute.


>No, no!  She was experimenting with lethal-injection formulas,
>having heard that potassium chloride will stop the heartbeat
>if injected into the bloodstream. 

Could she be trying to give someone rediation poisoning?


__________________________________________________________
One fun use for Potassium Chloride is to give
people who don't realize just how
much background readiation there is
a radiation scare.  I run a Powder X-ray
Diffraction lab with 2 Philips XRD machines - really
safe machines with no detectable leakage.

We have a really good X-ray counts detector out in the open for
anyone to test the machines.  Whenever a new user comes,
its standard to give a talk about safety and show
with the detector that there is nothing beyond
2 counts per second (background).  However, it is not
uncommon to get the question "do you feel safe working
all day near these machines?"  If the lack of response
from the counter doesn't convince them, I just stick
the counter probe into a bottle of Potassium Chloride -
and the counter starts humming happily - thats natuarally occurring
K40 doing its stuff.

All it takes from there is to say " you have "x" grams of this stuff
flowing through you body all the time and you are
worried about my health due to these machines?"

Does the Job.

-- 
  Lachlan Cranswick  -  CSIRO             _--_|\  lachlan@dmp.CSIRO.AU
  Division of Mineral Products           /      \ tel +61 3 647 0367
  PO Box 124, Port Melbourne 3207        \_.--._/ fax +61 3 646 3223
  AUSTRALIA                                    v
From: dsmith@uoft02.utoledo.edu
Newsgroups: sci.chem
Subject: AVS Chemistry Viewer and GAMESS
Date: 23 Dec 92 12:17:32 EST
Organization: University of Toledo, Computer Services

Has anyone written a module or modules to interface the AVS Chemistry Viewer
from Molecular Simulations, Inc. with the ab initio code GAMESS available
from Mark Gordon and Mike Schmidt?

Doug Smith
Assistant Professor of Chemistry
The University of Toledo
Toledo, OH  43606-3390

voice    419-537-2116
fax      419-537-4033
email    dsmith@uoft02.utoledo.edu
From: rrooks@ecs.umass.edu (Raymond Rooks)
Newsgroups: sci.chem
Subject: Potassium Chloride uses?
Date: 31 Dec 92 15:18:28 GMT

   Some strange woman came by the lab today and said that she was wanting to
know if we had some KCl.  I am wondering why she might have wanted this salt.

   She didn't look like she would have any class related reason for it,
espically since classes are over.  Can someone enlighten me as to what she
may have needed it for?

Ray

Newsgroups: sci.chem
From: r0th@ellis.uchicago.edu (Samuel Conway)
Subject: Preparation of C-14 labeled chloral hydrate
Reply-To: r0th@midway.uchicago.edu
Organization: University of Chicago Computing Organizations
Date: Tue, 29 Dec 1992 19:55:35 GMT

My colleagues and I are interested in preparing carbon-14 labeled
chloral (trichloroacetaldehyde) and/or the hydrate thereof.  We seek
a procedure for the preparation of pure material with a specific
activity of approx. 50 mCi/mmole for metabolic studies.  Unfortunately,
our technical library is somewhat lacking in appropriate chemical
literature.

The position of the radiolabel is not critical, though it is preferable
to have it in the C-2 position. 

Ah...and if we can do it without having to use chlorine gas, it would 
be nice!  :)

Should anyone have a workable procedure for the synthesis of chloral, I
would be very happy to hear it.  Many thanks in advance!

----
Dr. Samuel Conway         *  "If the guest isn't singing, 'Oh What a Beautiful
National Center for       *  Morning' I don't immediately think, 'Oh, there's
Toxicological Research,   *  another one snuffed it in the night!'  Another
Jefferson, AR             *  name in the Fawlty Towers book of Remembrance.
r0th@midway.uchicago.edu  *  I mean, this is a hotel, not the Burma Railway!"
From: Stan_Gruszka@mindlink.bc.ca (Stan Gruszka)
Newsgroups: sci.chem
Subject: Re: Glow Cubes
Date: 23 Dec 92 21:08:04 GMT
Organization: MIND LINK! - British Columbia, Canada

> Mark Robert Thorson writes:
>
> Msg-ID: <72240@cup.portal.com>
> Posted: 23 Dec 92 04:04:46 GMT
>
> Org.  : The Portal System (TM)
>
> I remember reading about these things.  I believe the phosphor was
> incorporated into an aerogel, with the tritium applied as a gas
> soaking the block.  Sounded neat to me.  As I recall, the big
> advantage is much higher light output than traditional tritium-based
> light sources.  I remember about 20 years ago Edmund Scientific used
> to sell light sources which were capsules of tritium gas internally
> coated with a phosphor.  I wish I had bought one now, but of course it
> would
> have decayed considerably by now (the half-life of tritium is about 5
> years).


For the sake of accuracy ... the half-life is 12.3 years.
Newsgroups: sci.chem
From: conklin@qucis.queensu.ca (Darrell Conklin)
Subject: Re: Left-handed sugar
Organization: Computing & Information Science, Queen's University at Kingston
Date: Sat, 2 Jan 1993 19:57:42 GMT

With regard to the discussion of sugars and configurations.

Our group has found that the hexopyranose sugars can be classified
into their 16 configurations solely on the basis of van der Waals
contacts between the oxygens on adjacent chiral centers.

The paper is 

	Conklin, Darrell, Suzanne Fortier, Janice Glasgow and Frank Allen.
	1992.  Discovery of Spatial Concepts in crystallographic databases.
	In Proceedings of the ML '92 Workshop on Machine Discovery.

The technique as presented does not distinguish between a configuration 
and its enantiomer, since distances are invariant under reflection.  

Darrell Conklin                                   conklin@qucis.queensu.ca
Department of Computing and Information Science   Tel: (613) 545-6301
Queen's University                                Fax: (613) 545-6513
Kingston, Ontario
Canada K7L 3N6
Newsgroups: sci.chem,sci.bio