From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Bos taurus (clone p17) sodium-calcium exchanger mRNA sequence.
Date: 31 Dec 92 01:30:05 GMT
Distribution: bionet
Checksum: 06347 8

LOCUS       BOVEXCHANG   4087 bp ss-mRNA            MAM       16-DEC-1992
DEFINITION  Bos taurus (clone p17) sodium-calcium exchanger mRNA sequence.
ACCESSION   L06438
KEYWORDS    sodium-calcium exchanger.
SOURCE      Bos taurus (library: lambda-gt10) adult heart cDNA to mRNA.
  ORGANISM  Bos taurus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae;
            Bovini.
REFERENCE   1  (bases 1 to 4087)
  AUTHORS   Aceto,J.F., Condrescu,M., Kroupis,C., Nelson,H., Nelson,N.,
            Nicoll,D.A., Philipson,K.D. and Reeves,J.P.
  TITLE     Cloning and expression of the bovine cardiac sodium-calcium
            exchanger
  JOURNAL   Arch. Biochem. Biophys. 298, 553-560 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     268..363
                     /codon_start=1
     misc_feature    3200..3249
                     /note="AT-rich region"
     CDS             268..3180
                     /codon_start=1
                     /translation="MLQFSLSPTLSMGFHVIAMVALLFSHVDHISAETEMEGEGNETG
                     ECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEV
                     ITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTA
                     GDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYII
                     LSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHE
                     GDRPSSKTEIEMDGKVVNSHVDSFLDGALVLEVDERDQDDEEARREMARILKELKQKH
                     PEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHE
                     VNTEVAENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANA
                     GSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVSLEASEDGILE
                     ASHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGN
                     VIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIG
                     EPRLVEMSEKKALLLNELGGFTITGKYLYGQPVFRKVHAREHPLPSTIITIADEYDDK
                     QPLTSKEEEERRIAEMGRPILGEHTRLEVIIEESYEFKSTVDKLIKKTNLALVVGTNS
                     WREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGW
                     ACFIVSILMIGLLTAFIGDLASHFACTIALKDSVTAVVFVALGTSVPDTFASKVAATQ
                     DQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF
                     AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF"
BASE COUNT     1057 a    950 c   1057 g   1023 t
ORIGIN      
        1 gaattcggga gaagccatca ccccgggtct tttttcacat ccagcccatg cagaccgatc
       61 ggccagctca accagagctg ccactgatct tccacactta agcaaaccac accagtgagt
      121 ggcgaacatc aactcgtgct tgaaaaatac caacttggag cccggtttga gaagctacat
      181 cagagtctcg agatgcgacg ctacaatctg cagttttcac tagcttccca gtaggttggg
      241 acagttggaa ctctgccatt gcccagcatg ctgcagttca gtctgtcacc caccttgtcg
      301 atgggatttc acgtgatagc catggtggct ctcttgtttt cccatgtgga ccatataagt
      361 gctgagacag aaatggaagg agaaggcaac gagactggcg agtgtactgg ctcctattac
      421 tgtaagaagg gggtgatttt acccatttgg gagccccagg acccttcctt tggagacaaa
      481 attgctagag cgactgtgta ttttgtggcc atggtctaca tgtttcttgg agtctcaatc
      541 attgctgacc ggttcatgtc ctctatagaa gtcatcacgt ctcaagagaa agaaatcacc
      601 ataaagaaac ccaatggaga gaccaccaag acaactgtga ggatctggaa tgagacagtg
      661 tccaacctga ccttgatggc cctggggtct tcagctccag agattctcct ttcagtaatc
      721 gaggtgtgtg gccataactt cactgcagga gaccttggcc ctagcaccat cgtggggagt
      781 gctgcattca acatgttcat catcattgcc ctttgtgtgt atgtcgtccc ggatggggag
      841 acaaggaaga tcaagcatct gcgtgtgttc tttgtgacag cagcatggag catctttgcc
      901 tatacctggc tttacatcat tttgtctgtc agctcccctg gggtcgtgga ggtctgggaa
      961 ggtttgctta ctttcttctt cttccccatc tgcgttgtgt ttgcttgggt ggcagacagg
     1021 aggcttctgt tttacaagta tgtctacaag aggtatcggg ctggcaagca gaggggaatg
     1081 attattgaac acgaaggaga caggccatct tccaagacag aaattgaaat ggatgggaaa
     1141 gtggtcaatt cccatgttga cagtttctta gatggagccc tggttctgga ggttgatgag
     1201 agggaccaag atgatgaaga agccaggcga gaaatggcta ggattctgaa ggaactcaag
     1261 cagaagcatc cagagaagga aatagagcaa ttaatagaat tagccaatta ccaagtctta
     1321 agtcagcagc aaaaaagtcg agcgttttac cgtattcaag ctacccgcct gatgaccgga
     1381 gcaggcaaca ttttaaagag gcatgcagca gaccaagcca ggaaagctgt cagcatgcat
     1441 gaggtcaaca cggaagtggc tgaaaatgac cctgtcagta agatcttctt tgaacaaggg
     1501 acatatcagt gtctggagaa ctgtggcaca gtagccctga ccattatccg cagaggtggt
     1561 gatttgacca acactgtgtt tgttgacttc agaacagagg atggcacagc caatgctgga
     1621 tctgattacg aatttaccga aggaactgtg gtctttaagc ctggtgagac ccagaaggaa
     1681 atcagagttg gcatcattga tgatgacatc tttgaggagg atgagaattt ccttgtgcat
     1741 ctcagcaacg tcaaagtatc tttggaagcc tcggaagacg gcatcctgga agccagtcat
     1801 gtctctaccc ttgcttgcct gggatccccc tccactgcca ccgtgactat ttttgatgat
     1861 gaccatgctg gcatctttac ttttgaggaa ccggtgactc atgtgagtga gagcattggc
     1921 atcatggagg tgaaagttct gagaacatct ggagcacgtg gaaatgttat cgttccctat
     1981 aagaccattg aggggaccgc cagaggtgga ggggaggact ttgaggacac atgcggagag
     2041 ctcgagttcc agaatgacga aattgtcaaa acaatatcag tcaaggtaat tgatgatgag
     2101 gagtatgaga aaaacaagac cttcttcctt gagattggag agccccgcct ggtggagatg
     2161 agtgagaaga aagccctgtt attgaatgag cttggtggct tcacaataac agggaaatac
     2221 ctgtatggcc agcctgtctt caggaaagtt catgctagag aacatccact cccctctact
     2281 ataatcacca tcgcagatga atatgatgac aagcagccac tgaccagcaa agaggaggaa
     2341 gagaggcgca ttgcggaaat ggggcgcccc attctgggag agcacaccag actggaggtg
     2401 atcattgaag aatcctacga gttcaagagt accgtggaca aactgattaa gaagacaaac
     2461 ctagccctcg tggttgggac gaacagctgg agagagcagt tcatcgaggc gatcactgtc
     2521 agtgctgggg aagatgacga tgacgacgaa tgtggggagg agaagctgcc ctcctgtttt
     2581 gactacgtga tgcactttct gactgtgttc tggaaggtcc tcttcgcctt tgtccccccg
     2641 acagagtact ggaacggctg ggcgtgtttc atcgtctcca tcctcatgat cggcctactg
     2701 acggctttca ttggagacct cgcttcccac ttcgcctgca ccatcgccct gaaggattcc
     2761 gtgaccgcgg tggtgttcgt tgcgcttgga acctcagtgc cagacacatt tgcaagcaaa
     2821 gtggccgcca cccaggacca gtatgcggat gcatccatag gtaacgtcac aggcagcaac
     2881 gcggtgaacg tcttcctggg catcggtgtg gcctggtcca tcgccgccat ctaccacgcg
     2941 gccaacgggg aacagttcaa agtgtcccct ggcacgctag ctttttctgt cactctcttc
     3001 accatttttg ctttcatcaa tgtgggggtg ctgctgtatc ggcggaggcc agaaattgga
     3061 ggtgagctgg gtgggccccg gactgccaag ctcctcacat cctgcctctt tgtgctcctg
     3121 tggctcttgt acattttctt ctcctccctg gaggcctact gccacataaa aggcttctaa
     3181 aggaacaatc agatgtagta aatttatata tatatacata tatatatata cataaaaatt
     3241 atgtataatg aacagaggaa actggcattt gtcatgtcca cccacctgct gatggaatcc
     3301 agcttcaaga gcagactctg tactagggcc ggagagagaa ggcatcacct cccgtttccc
     3361 aggggcgttc gtcttgttga accaggcatg gaggcagggc catctttacg tcagctcagc
     3421 ccagaagcgg tgtgttctcc ccgggttcat aaatccttaa gttctttgat ttgttttctg
     3481 tttttgcttg ttttgggtcg gggtagggag gtggttgatg ttagggtttg gttttggttt
     3541 tgcaggggga agatcagggt ttgtggtcct cttgtgggag gtgatgtcca atctcaatgg
     3601 taaaaatgga aatcaggaag atgactctcc ctttgcccaa aaactttaaa aattattttg
     3661 gagtaagaaa ggaaacgggc atggaagaag aaagaagcat gtcttcacca tattactaaa
     3721 tttcatgcct tatctctgga gtgggagcag aggtgaagtc ctccctccaa gaagaaacag
     3781 gggagctgga atggagccaa gaagagtcat ggttctagat acagtctgat gtttaaagat
     3841 acatcgctgc ctggcaccct tgttcaacag gtacaaaaac aacatgccta gattcccagg
     3901 aacgcacaaa gtcctttctt atctcttcag cgctggactg tgattagcaa ggccctgatt
     3961 ctgatgttct acacccgctg attccccagc cctcccatcc caaacccctt ctccggaccc
     4021 tttacccctc gtacaaacag gaagaataac tccattcaaa aagcacacca tcctttccat
     4081 tcgcatc
//