From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens DNA for IG kappa JC region
Date: 4 Sep 92 10:04:13 GMT
Distribution: bionet
Checksum: 41048     9

LOCUS       HUMIGKA      5364 bp ds-DNA             PRI       04-SEP-1992
DEFINITION  H.sapiens DNA for IG kappa JC region
ACCESSION   X67858
KEYWORDS    Ig kappa light chain.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5364)
  AUTHORS   Whitehurst,C., Henney,H.R., Max,E.E., Schroeder,H.W., Stuber,F.,
            Siminovitch,K.A. and Garrard,W.T.
  TITLE     Nucleotide sequence of the intron of the Germline Human K
            Immunoglobulin gene connecting the J and C regions reveals a matrix
            association region (MAR) next to the enhancer.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: is_germline=Y;
            From EMBL    entry HSIGKA;  dated 12-AUG-1992.
FEATURES             Location/Qualifiers
     misc_feature    252..290
                     /note="J1 region"
     misc_feature    613..651
                     /note="J2 region"
     misc_feature    917..955
                     /note="J3 region"
     misc_feature    1252..1290
                     /note="J4 region"
     misc_feature    1570..1608
                     /note="J5 region"
     misc_feature    2661..3661
                     /note="matrix association region (MAR)"
     enhancer        3742..3866
     misc_feature    4491..4993
                     /note="constant region"
BASE COUNT     1623 a   1035 c   1114 g   1592 t
ORIGIN
        1 ataaataata agcagtccag atgtggcaag ttgcaaagaa aggaaccatc aggccataga
       61 cgtaaatata ttctcttctt ggattttagg tctcacctaa agaaaataaa cacatgctat
      121 gtcagagaag cctcagggtt tccacacctg ctcgaaaagg gagttgagct tcagcagctg
      181 acccaggact ctgttcccct ttggtgagaa gggtttctgt tcagcaagac aatggagagc
      241 tctcactgtg gtggacgttc ggccaaggga ccaaggtgga aatcaaacgt gagtagaatt
      301 taaactttgc ttcctcagtt gtctgtgtct tctgttccct gtgtctatga agtgatctat
      361 aaggtgactc tgcaatcagc ctctgatatc cttcagggaa aagataaaga taagtctgta
      421 gtcaaactcg agaattgatt gcacattttc tttgaagagc aagcaagatt cagtcattgg
      481 gtgagaataa cttgtctaag taatagcttc agaaatgtcc tggggaacat aacatgttct
      541 ggacagagcc ttggtcaatt gtcagaaagg gagtttttgt ataggaggga agttaagagg
      601 aaccattgtg tgtacacttt tggccagggg accaagctgg agatcaaacg taagtacttt
      661 tttccactga ttcttcactg ttgctaatta gtttactttg tgttcctttg tgtggatttt
      721 cattagtcgg atgccaggga tctaacaaac ttcattccca ggttaggtac agaggagggg
      781 aaattgttcc acaggacgct agcttgtggc taatttttaa gatttctaaa tcaaaataac
      841 ttcattgggg gaaagaggct tgctgagctt tcagggaggt ttttgtaaag ggaaaagtta
      901 agacgaatca ctgtgattca ctttcggccc tgggaccaaa gtggatatca aacgtaagta
      961 catctgtctc aattattcgt gagattttag tgccattgta tcatttgtgc aagttttgtg
     1021 atattttggt tgaataaacc tggtgaccca gaagtaaata gcaggacacc agaaaatgaa
     1081 cttaaaaagc tgagcaaata gacgaatcat tgggtttgag aggagaatag gattcatggg
     1141 ggaaatgggg aagaaatagc tagatttttc tctgaacaag cagcctatct catatgattg
     1201 gcttcaagag aggtttttgt tgaggggaaa gggtgagatc cctcactgtg gctcactttc
     1261 ggcggaggga ccaaggtgga gatcaaacgt aagtgcactt tcctaatgct ttttcttata
     1321 aggttttaaa tttggagcgt ttttgtgttt gagatattag ctcaggtcaa ttccaaagag
     1381 taccagattc tttcaaaaag tcagatgagt aagggataga aaattagttc atcttaagga
     1441 acagccaagc gctagccagt taagtgaggc atctcaattg caagattttc tctgcatcgg
     1501 tcaggttagt gatattaaca gcgaaaagag atttttgtta aggggaaagt aattaagtta
     1561 acactgtgga tcaccttcgg ccaagggaca cgactggaga ttaaacgtaa gtaatttttc
     1621 actattgtct tctgaaattt gggtctgatg gccagtattg acttttagag gcttaaatag
     1681 gagtttggta aagattggta aatgagggca tttaagattt gccatgggtt gcaaaagtta
     1741 aactcagctt caaaaatgga tttggagaaa aaaagattaa attgctctaa actgaatgac
     1801 acaaagtaaa aaaaaaaagt gtaactaaaa aggaaccctt gtatttctaa ggagcaaaag
     1861 taaatttatt tttgttcact cttgccaaat attgtattgg ttgttgctga ttatgcatga
     1921 tacagaaaag tggaaaaata cattttttag tctttctccc ttttgtttga taaattattt
     1981 tgtcagacaa caataaaaat caatagcacg ccctaagaaa aatcagggaa aagtgaagtg
     2041 tacctatttg ctatgtagaa gaggcagctt acttgaaaat cagcagcaat gttgttttta
     2101 gagtctgtaa taagtaataa actcaaaaag acacattcta taggaataag ggcttcacag
     2161 atagagctca ttttttaaaa atccaatttg tacattagac taaacgtgaa attatctctt
     2221 attgtaatgg tggaaaggtg gttattccca aaagctcaat ctcaaagaaa tgtgtttaaa
     2281 tgaaaaaaag taaataattg cattttttaa tgaccgtggg tctgtgaaaa aaataggaaa
     2341 tattttaaag agtatgttct ttcattatcc tctgttatta cttgtctaca tttttattct
     2401 gccaagaagg ccgtggcacc gcgagctgta gacagagccg cggtctttct cgattgagtg
     2461 gctttggtgg ccatgccacc gcgctcttgg ggcagccgcc ttgccgctat gccgtggcca
     2521 ccctgtgtct gcccgattaa tgctgccgta gccagctttc ctgatgcaca gtgatacaaa
     2581 taatgccact aagggaaaga gaacagaaac gtaatgggcg ctgagctggg aaaaccaggg
     2641 agaagactga tttattagag atttcagaaa taaaattcac attcattatg atatctcatt
     2701 agtgaaaatt tccattaggg gattgtaaat aatttaaagc tttttttttt tcagtgctat
     2761 ttaattattt caatatcctc tcatcaaatg tatttaaata acaaaagctc aaccaaaaag
     2821 aaagaaatat gtaattcttt cagagtaaaa atcacaccca tgacctggcc actgagggct
     2881 tgatcaattc actttgaatt tggcattaaa taccattaag gtatattaac tgattttaaa
     2941 ataagatata ttcgtgacca tgtttttaac tttcaaaaat gtagctgcca gtgtgtgatt
     3001 ttatttcagt tgtacaaaat atctaaacct atagcaatgt gattaataaa aacttaaaca
     3061 tattttccag taccttaatt ctgtgatagg aaaattttaa tctgagtatt ttaatttcat
     3121 aatctctaaa atagtttaat gatttgtcat tgtgttgctg tcgtttaccc cagctgatct
     3181 caaaagtgat atttaaggag attattttgg tctgcaacaa cttgatagga ctattttagg
     3241 gcctttttaa agctctatta aaactaactt acaacgattc aaaactgttt taaactattt
     3301 caaaatgatt ttagagcctt ttgaaaactc ttttaaacac tttttaaact ctattaaaac
     3361 taataagata acttgaaata attttcatgt caaatacatt aactgtttaa tgtttaaatg
     3421 ccagatgaaa aatgtaaagc tatcaagaat tcacccagat aggagtatct tcatagcatg
     3481 tttttccctg cttattttcc agtgatcaca ttattttgct accatggtta ttttatacaa
     3541 ttatctgaaa aaaattagtt atgaagatta aaagagaaga aaatattaaa cataagagat
     3601 tcagtctttc atgttgaact gcttggttaa cagtgaagtt agttttaaaa aaaaaaaaaa
     3661 ctatttctgt tatcagctga cttctcccta tctgttgact tctcccagca aaagattctt
     3721 attttacatt ttaacctact gctctcccac ccaacgggtg gaatccccca gagggggatt
     3781 tccaagaggc cacctggcag ttgctgaggg tcagaagtga agctagccac ttcctcttag
     3841 gcaggtggcc aagattacag ttgacctctc ctggtatggc tgaaaattgc tgcatatggt
     3901 tacaggcctt gaggcctttg ggagggctta gagagttgct ggaacagtca gaaggtggag
     3961 gggctgacac cacccaggcg cagaggcagg gctcagggcc tgctctgcag ggaggtttta
     4021 gcccagccca gccaaagtaa cccccgggag cctgttatcc cagcacagtc ctggaagagg
     4081 cacaggggaa ataaaagcgg acggaggctt tccttgactc agccgctgcc tggtcttctt
     4141 cagacctgtt ctgaattcta aactctgagg gggtcggatg acgtggccat tctttgccta
     4201 aagcattgag tttactgcaa ggtcagaaaa gcatgcaaag ccctcagaat ggctgcaaag
     4261 agctccaaca aaacaattta gaactttatt aaggaatagg gggaagctag gaagaaactc
     4321 aaaacatcaa gattttaaat acgcttcttg gtctccttgc tataattatc tgggataagc
     4381 atgctgtttt ctgtctgtcc ctaacatgcc ctgtgattat ccgcaaacaa cacacccaag
     4441 ggcagaactt tgttacttaa acaccatcct gtttgcttct ttcctcagga actgtggctg
     4501 caccatctgt cttcatcttc ccgccatctg atgagcagtt gaaatctgga actgcctctg
     4561 ttgtgtgcct gctgaataac ttctatccca gagaggccaa agtacagtgg aaggtggata
     4621 acgccctcca atcgggtaac tcccaggaga gtgtcacaga gcaggacagc aaggacagca
     4681 cctacagcct cagcagcacc ctgacgctga gcaaagcaga ctacgagaaa cacaaagtct
     4741 acgcctgcga agtcacccat cagggcctga gctcgcccgt cacaaagagc ttcaacaggg
     4801 gagagtgtta gagggagaag tgcccccacc tgctcctcag ttccagcctg accccctccc
     4861 atcctttggc ctctgaccct ttttccacag gggacctacc cctattgcgg tcctccagct
     4921 catctttcac ctcacccccc tcctcctcct tggctttaat tatgctaatg ttggaggaga
     4981 atgaataaat aaagtgaatc tttgcacctg tggtttctct ctttcctcaa tttaataatt
     5041 attatctgtt gtttaccaac tactcaattt ctcttataag ggactaaata tgtagtcatc
     5101 ctaaggcgca taaccattta taaaaatcat ccttcattct attttaccct atcatcctct
     5161 gcaagacagt cctccctcaa acccacaagc cttctgtcct cacagtcccc tgggccgtgg
     5221 taggagagac ttgcttcctt gttttcccct cctcagcaag ccctcatagt cctttttaag
     5281 ggtgacaggt cttacggtca tatatccttt gattcaattc cctgggaatc aaccaaggca
     5341 aatttttcaa aagaagaaac ctgc
//