From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.norvegicus mRNA for neuro-D4 protein
Date: 3 Jan 93 22:08:48 GMT
Distribution: bionet
Checksum: 08439 9

LOCUS       RATND4P      3233 bp ss-RNA             ROD       21-DEC-1992
DEFINITION  R.norvegicus mRNA for neuro-D4 protein
ACCESSION   X66022
KEYWORDS    developmentally regulated gene.
SOURCE      Rattus norvegicus RNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3233)
  AUTHORS   Buchman,V.L., Ninkina,N.N., Bogdanov,Y.D., Bortvin,A.L.,
            Akopian,H.N., Kiselev,S.L., Krylova,O.Y., Anokhin,K.V. and
            Georgiev,G.P.
  TITLE     Differential splicing creates a diversity of transcripts from a
            neurospecific developmentally regulated gene encoding a protein
            with new zinc-finger motifs
  JOURNAL   Nucleic Acids Res. 20, 5579-5585 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=Wistar; *source: stage=P7-9 days; *source: tissue=
            cerebral cortex; *source: clone_library=lambda gt10 cDNA; *source:
            clone=pd4;p1-18C;
               From EMBL    entry RNND4P;  dated 30-NOV-1992.
FEATURES             Location/Qualifiers
     mRNA            join(53..81,966..2130)
                     /gene="neuro-d4"
                     /note="most abundant mRNA variant of differentialsplicing"
     mRNA            join(1457..1517,1532..2130)
                     /gene="neuro-d4"
                     /note="variant of differential splicing III"
     exon            1..81
                     /evidence="EXPERIMENTAL"
                     /note="exon 1"
     misc_feature    53..55
                     /product="nuclear DNA-RNA bindingprotein"
                     /gene="neuro-d4"
                     /note="start codon for most abundant mRNAvariant of
                     differential splicing"
     exon            82..965
                     /evidence="EXPERIMENTAL"
                     /note="exon 1a, variant of differential splicingI"
     exon            966..1026
                     /evidence="EXPERIMENTAL"
                     /note="exon 2"
     exon            1027..1234
                     /evidence="EXPERIMENTAL"
                     /note="exon 3"
     misc_feature    1102..1104
                     /product="nuclear DNA-RNA bindingprotein"
                     /gene="neuro-d4"
                     /note="start codon for variant ofdifferential splicing I"
     mRNA            1102..2130
                     /gene="neuro-d4"
                     /note="variant of differential splicing I"
     exon            1235..1362
                     /evidence="EXPERIMENTAL"
                     /note="exon 4"
     exon            1363..1452
                     /evidence="EXPERIMENTAL"
                     /note="exon 5"
     misc_feature    1363..1452
                     /evidence="EXPERIMENTAL"
                     /note="deletion of exon 5 variant of differentialsplicing
                     II"
     exon            1453..1531
                     /evidence="EXPERIMENTAL"
                     /note="exon 6"
     misc_feature    1457..1459
                     /product="nuclear DNA-RNA bindingprotein"
                     /gene="neuro-d4"
                     /note="start codon for variant ofdifferential splicing
                     III"
     misc_feature    1518..1531
                     /evidence="EXPERIMENTAL"
                     /note="deletion, variant of differential splicingIII"
     exon            1532..1563
                     /evidence="EXPERIMENTAL"
                     /note="exon 7"
     exon            1564..1714
                     /evidence="EXPERIMENTAL"
                     /note="exon 8"
     exon            1715..1834
                     /evidence="EXPERIMENTAL"
                     /note="exon 9"
     exon            1835..1947
                     /evidence="EXPERIMENTAL"
                     /note="exon 10"
     misc_feature    1948..1977
                     /evidence="EXPERIMENTAL"
                     /note="insertion, variant of differential splicingIV"
     exon            1978..2059
                     /evidence="EXPERIMENTAL"
                     /note="exon 11"
     variation       2023
                     /partial
                     /note="replace(2023,'c')"
     exon            2060..3233
                     /evidence="EXPERIMENTAL"
                     /note="exon 12"
     variation       2195
                     /partial
                     /note="replace(2195,'c')"
     polyA_signal    3189..3194
     polyA_signal    3207..3212
BASE COUNT      656 a    811 c    994 g    772 t
ORIGIN      
        1 tgggaggacc gacccggcag ggacctgctg ggggcaggac ccggggagca agatggccac
       61 ggtcatcccc agccccctga ggtggtgcgg gcgtgcgcga ggcgggggag tcagcgcggg
      121 cgagtctgtg tggctgcgag tgcgtgtgtg tgtatgtgtg cggccgctgg gggtggggct
      181 ggtggggtgt cagggggctg tcaccgcgtg cgggggtgcg agggtatgtg actgtgggtg
      241 tctggcaaga atggtgtacg acgcgttgct cctggacggg tggagggcgt gggggagggg
      301 tctccaagga tttttagggg aaaggggtca tgtcccctcc cagggatgct agggtttgag
      361 agagggtaaa tgatttagag aagatggggc ctgggtacac tcgagtcgaa cccacgctac
      421 ctttgtcttg gggtgtggag tgtgttgtga gacttataca ttgctttttg ttttgtagct
      481 gaatgtgtgg gtatgtatag gatttctttt attctgcact acctatctga gtatttgggt
      541 ctctaagtgt gtgcacatgt ctggtgaaac tgcaccattt atgttccgtg tctctggata
      601 gggagctgta gggataggtc taaatatttg cacgaacaga ggcagaccgg actgtccctc
      661 tgtttccaag gggtgtacct gtgtttgtga atgtatttta aatttgggtt tgtttttccc
      721 cggagggtgc gaatgtgtgt atgtgtacct gtataaatct ctgtgatgtc tttgtattgt
      781 gtgtttggct gaagtgtctc tggatgaata tgtaagcgca tatgtaaatg attctagggt
      841 ccctatcttt tgacaacgtg tgactgttgg gatgagtgtt gtgtggtgtg tttccatgtt
      901 gtggggcttt gtggataatc ttcctctgga cacatctggg gtctctggat acatggcatt
      961 catagccttg gcgaggactt ctaccgggag gccatcgagc actgccgcag ctacaacgcg
     1021 cgcctgtgtg ccgagcgcag cctgcgcctg cccttcctcg actctcagac cggcgtggct
     1081 cagaacaact gctacatctg gatggagaag acccaccgcg ggcctggttt ggccccagga
     1141 cagatctaca cttaccccgc ccgctgttgg aggaagaaac ggagactcaa catcctggag
     1201 gaccccaggc tccggccctg cgagtacaag atcgattgtg aggcacctct gaagaaggag
     1261 ggtggcctcc cggaagggcc agtccttgag gctctgctgt gcgctgagac tggagagaag
     1321 aaagtggagt tgaaggagga ggagaccatt atggactgtc agaaacagca gttgctggag
     1381 tttccgcatg atctcgaggt agaagacttg gaggaagaca ttcccaggag gaagaacagg
     1441 gccaaaggaa aggcgtatgg cattggaggt ctccggaaac gccaggacaa cgcatccttg
     1501 gaggaccgag acaagccgta cgtctgtgat atctgtggga agaggtataa gaaccggcca
     1561 gggcttagct accactacac ccacacccac ctggctgagg aggaggggga ggagcacact
     1621 gagcgccacg ccctgccttt ccaccggaaa aacaaccata aacagtttta caaagaattg
     1681 gcctgggtcc ccgaggcaca gaggaaacac acagccaaga aagcaccaga tggcactgtc
     1741 atccccaatg gctactgtga cttttgcctg gggggctcca agaagactgg atgtcctgag
     1801 gacctcatct cctgtgcgga ctgcgggcga tcaggacatc cctcgtgttt acagttcacg
     1861 gtgaacatga ccgcagccgt gcggacctac cgctggcagt gtatcgaatg caagtcctgc
     1921 agcctgtgtg gcacctcgga gaatgacggt gccagctggg cgggtctcac cccccaggac
     1981 cagctgctgt tctgtgacga ctgcgatcgg ggttaccaca tgtactgcct gagccctccc
     2041 atggcggagc ccccggaagg gagctggagt tgccacctct gtctccggca cttgaaagaa
     2101 aaggcctccg cttacatcac cctgacttag acctggctct gcttctccag gacctttggg
     2161 tggtgctatc ctcggcctct tggagctcct gacttttccc gcctggtgtc cccagtggaa
     2221 gggatagggt gaagcccaga gaggggccaa ggcggtctcc ctctgcaagt ggaatgttac
     2281 cctgagggag ggtgggtcca gcagggtccc tcctgtcccc catcttcatt ccttgacaag
     2341 tgggcaccag gcttctgctc ccctcaaagc cataccgcct ctgggcgggc atagaggggt
     2401 agtggatgcc agccagtggc acggaaaaag cctttttcta aagaaaaaga caaaacgtga
     2461 aaaaaaaaaa aggaaaaaaa aaaagaaatt aatatataca aagattcctc taagcctggc
     2521 tgggtggggg gccactgagt gtctgctggg acctgacttt accagtttcc tgaatggccc
     2581 ctccccaccc catttctgga gttgcaattg tctcaactcc catctgaggt gggtaccaca
     2641 ccttcctcac agccaggcca ggtgggcatg gtgcccacac actgccccct cccggtaccc
     2701 accgtggata ctgcatgatg tgaaccatgg ttttgaactc ttcctgcccc tcctttgaga
     2761 gccccgccct gcgcccaccc ggtgcctgcc agacctgggg cttgcagctg ggggaggccg
     2821 gtggggtgag gcaggcaggc aggcagccag cccgctgcaa tgagaagaag cacagattgc
     2881 aatggactca gttgtttttt gttttttgtt tttgtttttg tttttttttc tttctttctc
     2941 ccttctcaac cctttccttc cctacccagc caggctgggc tgcctccttc cccccatcgc
     3001 tagccatttt gggggtggca aggaggtgtg gtcgtttctc gtggttgtgt gtgtttgttg
     3061 ttcgggtttt aaaaaaggga aattgagact gcaagtgggg ggaggtggag ggtctggggg
     3121 agtctgcccc ccaacccagg agtacccccc ttgccaccaa gtctccttta ttgcctgcct
     3181 ctgctgtgaa ttaacttgtt ctgtgtatta aactgggccg gacccctctg ccc
//