From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: A.californica mRNA for BiP/GRP78 homologue
Date: 11 Sep 92 10:02:13 GMT
Distribution: bionet
Checksum: 16486     6

LOCUS       APLBIP       2483 bp ss-RNA             INV       11-SEP-1992
DEFINITION  A.californica mRNA for BiP/GRP78 homologue
ACCESSION   Z15041
KEYWORDS    BiP/GRP78 homologue; heat shock protein 70;
            major protein chaperon of the endoplasmic reticulum.
SOURCE      Aplysia californica RNA.
  ORGANISM  Aplysia californica
            Eukaryota; Animalia; Eumetazoa; Mollusca; Gastropoda;
            Opisthobranchia; Anaspidea; Aplysiidae.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Kuhl,D.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 2483)
  AUTHORS   Kuhl,D., Kennedy,T., Barzilai,A. and Kandel,E.R.
  TITLE     Long-Term Sensitization Training in Aplysia Leads to an Increase in
            the Expression of BiP, the Major Protein Chaperon of the
            Endoplasmic Reticulum
  JOURNAL   J. Cell Biol. (1992) In press
  STANDARD  full automatic
COMMENT     From EMBL    entry ACBIP;  dated 02-SEP-1992.
FEATURES             Location/Qualifiers
     CDS             132..2135
                     /product="BiP/GRP78"
                     /codon_start=1
                     /translation="MDRFTPFFLLVILFSSNLLVRADGDEEDEGDKKKSEVGTVIGID
                     LGTTYSCVGVFKNGRVDIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTSNPENTI
                     FDVKRLIGRTFDDKSVQHDIKFYPFKVTNANNKPHIQAATGEGDRSFAPEEISAMVLS
                     KMRDIAEEYLGKKITNAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAY
                     GLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVSTNGDTHLGGEDFDQRVMEHFI
                     KLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSSAHQVRLEIESFFDGEDFSESLTRA
                     KFEELNMDLFRSTMKPVKQVLEDADLKTDDIDEIVLVGGSTRIPKVQQLVKEYFNGKE
                     PSRGINPDEAVAYGAAVQAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNT
                     VIPTKKSQIFSTAADNQPTVTIQVYEGERSMTKDNHLLGKFDLTGIPPAPRGVPQIEV
                     TFEIDVNGILKVTAEDKGTGSKNQIVIQNDQNRLSPEDIERMINDAEKYADEDKKVKE
                     KVDAKNELESYAYSLKNQIGDKEKLGAKLSDEDKEKITEAVDEAIKWLESNAEAESEA
                     FNEKKTELEGIVQPIMTKLYEQSGGAPPPSGEEESEEAEKDEL"
BASE COUNT      701 a    497 c    633 g    652 t
ORIGIN
        1 gaagcagtaa ctgtagcagg tcacatagtt cgggaacaca aaattgttgt tccattgcat
       61 tttgaaggca cccgaagtgg ttaagacatc gttttcggtt ggaagttttc cttgcctttg
      121 gtaaaatcaa aatggatcgg ttcacaccct tctttttgct tgtcatactg ttcagctcaa
      181 accttttggt acgggcagat ggtgatgaag aagatgaagg agataaaaag aagtcagaag
      241 ttggcactgt aattggcatt gatcttggaa caacatactc ttgtgttggt gttttcaaaa
      301 atggcagagt tgacatcatt gcaaacgacc agggaaatcg tatcacacca tcgtatgttg
      361 cctttaccgc tgatggtgaa cgtctgatcg gagacgctgc caagaatcag ttgacatcca
      421 atcctgagaa cacaattttt gatgtgaaac gtttgattgg gcgcactttt gatgacaagt
      481 ctgttcagca tgatatcaag ttttaccctt tcaaggtcac taatgcaaac aacaaacctc
      541 acattcaagc agctactggt gagggtgata gatcttttgc cccagaggaa atttcggcta
      601 tggtcctttc caaaatgaga gatattgctg aggagtactt gggaaaaaag attaccaacg
      661 ctgttgtcac tgtcccagcc tacttcaacg atgctcagcg tcaggctacc aaggatgccg
      721 gaacaattgc tggtctcaat gtgatgagaa tcatcaatga gccaactgct gctgccattg
      781 cctatggttt ggacaagaaa gagggagaaa agaacatctt ggtgtttgac cttggtggtg
      841 gaacttttga tgtgtctctg ctcaccattg acaatggtgt gtttgaggtg gtttctacaa
      901 acggtgacac tcacttgggt ggtgaggact ttgatcagcg tgtcatggaa cacttcatca
      961 agctgtacaa gaaaaagaag ggcaaggaca tcaggaagga caaccgtgct gtgcagaaac
     1021 tgcgtcgtga ggttgagaag gcaaagcgtg ctctctcttc tgcccatcaa gtccgtctgg
     1081 agattgagtc tttcttcgat ggcgaggact tctctgaatc tcttacccgt gccaaatttg
     1141 aggaattgaa catggatctg ttccgttcta ccatgaagcc agtgaaacag gtgttggaag
     1201 atgctgactt gaagactgat gacattgatg aaattgtgtt ggttggtggt tctactcgta
     1261 tccctaaggt ccaacagctt gtgaaggagt acttcaatgg caaggagcca agccgaggca
     1321 tcaaccccga cgaagctgtg gcttacggag ctgccgtgca ggctggcgtg ctgagtggtg
     1381 aggaggacac tggcgatctt gtgttgttgg acgtcaaccc tctgaccatg ggtattgaga
     1441 ctgttggagg cgtcatgacc aagctcattc ccaggaacac tgtcatcccc accaagaagt
     1501 cccagatctt ctccacggct gctgacaacc agcccactgt caccattcag gtttacgagg
     1561 gagaacgttc catgacaaag gataaccatc tccttggaaa gtttgatctg accggaatcc
     1621 ccccagctcc tcgtggtgtg ccccagattg aggtcacttt cgaaattgac gtcaacggta
     1681 tcctcaaggt gacagcagaa gacaaaggca ctggcagcaa gaaccaaatt gtcatccaaa
     1741 atgaccagaa cagattgtcg ccagaggaca ttgagcgtat gatcaacgat gctgaaaagt
     1801 atgctgatga ggataagaaa gttaaggaga aggtggatgc caagaacgag ttggaaagct
     1861 atgcctattc tttgaagaac cagatcggag ataaggaaaa attgggagcc aagttgagcg
     1921 acgaggacaa ggaaaaaatc acagaggctg tcgatgaggc cattaagtgg ttggagagca
     1981 acgcagaggc agaatctgag gctttcaatg agaagaaaac agaattggaa ggtattgtgc
     2041 agcctatcat gacaaaactg tatgaacagt ccggcggtgc cccaccacca tcaggagaag
     2101 aggaatcgga ggaagccgag aaggacgagt tatgagtgtt cctgttagtt attagcattt
     2161 atcatctgta tttctcgctt cagtacgtcc aagatccttt atttggcaca aaaaaaaaga
     2221 caaacttttt tctgggatct cttttattca acttagctga aaaagataaa cttttgtttg
     2281 gtttgagtca aagatactgc tgaattctgt gtcagtgacc tggtggggga tgaactgatt
     2341 cacgaacttt ccatagatca aattatggac tcatttccat tgtcagaagt attgtttact
     2401 atacaaatcc tgttgttact ttatcggtat gaagtatgaa tggccgtgag tgattgcatg
     2461 gtgggtgttt cagtgaccat tgg
//