HDTenEightyP/NetNews huggingface dataset:
From: cyao@sal-sun95.usc.edu (Miles Yao)
Newsgroups: sci.med,sci.engr.biomed
Subject: Re: HELP NEEDED: lookin' for a physiological model of heart rhythms
Date: 13 Apr 1992 16:17:48 -0700
Organization: University of Southern California, Los Angeles, CA
Distribution: world
NNTP-Posting-Host: sal-sun95.usc.edu


Some clarifications on my request last time:

Specifically, I need a model that embodies the schematic below.  It does not
even need to model any arrhythmia: all that's necessary is the ability to 
"disconnect" the normal sinus rhythm from heart rate.  Although it does need
to be a dynamic system that can sustain itself autonomously, varying its
behaviour as perturbations(exercise) are presented.


			physical/mental exercise
			  or postural change
                         (in what parameter?)
		       /                      \
		      /                        \
                     |                          |
		     V                          V
	  hemodynamic indicators        normal sinus rhythm
         (EKG - QT interval, VDG,        (for comparison)
	 activity, minute ventilation,         
         d(V systolic pressure), etc.)          |
          .                                    /
          .          ^                        /
          .          |                       /
          .           \                     /
          .            \                   /
          .             \___ heart rate < ----------- pacemaker stimuli
          .                                             ^
          .                                             .
	  .........> (PACEMAKER SYSTEM) .................



The only remotely close model I've got is Plonsey, J Electrocardiology
12(4): 337, 1979, in which he modeled ventricular depolarization gradient
(QRS area) as:

       QRS                          _  _
      A    = V   * integral(C/theta*am*l dv)
              max

                    Ai/Ae
and   C = ---------------------------
 	    1/rhoi + (Ai/Ae)(1/rhoe)


where rhoi, rhoe are the intracellular and extracellular conductivity, Ai, Ae
the intracellular and interstitial cross-sectional areas of each fiber, Vmax
the magnitude of ventricular action potential (= height of QRS?), theta the
propagation velocity, am a "unit vector in the direction of -grad(Vm)"(?),
and l the lead vector field.  It seems exercise enters the equation through
theta, although I do not know the exact relationship (linear?).

Presently this model is useless as it is not a self-contained dynamical 
system, and I have no data to set the initial values.  Any advice on putting
together the rest of the pieces?





(*) M I L E S   Y A O  =============================<cyao@pollux.usc.edu>


	      "Sometimes you take a false-first picture.  You
	       pretend to take the picture, the subject relaxes.
	       _Then_ you take the real picture."
	      				      - W. S. Burroughs

	      "I just think any picture you take is a good picture."
					      - Andy Warhol
From: cjm@naucse.cse.nau.edu (Chris McConnell)
Newsgroups: sci.med
Subject: NEED ADVICE:  Over production of sweat under arms
Date: 14 Apr 92 16:30:43 GMT

I have a friend (woman) who can't control her sweat.  No, the 
over-the-counter anti-persperants do not work.  She is into 
wearing layers of clothing to hide this affliction, but she wants
to "fix" it somehow.  Does anyone have any advice?

Thanks,
Chris
From: georgec@eng.umd.edu (George B. Clark)
Newsgroups: sci.med
Subject: Re: Is baloon angioplasty safe?
Date: 9 Apr 92 22:35:07 GMT
Article-I.D.: eng.1992Apr09.223507.23150
Distribution: na
Organization: College of Engineering, University of Maryland, College Park



"Bypassing Bypass" by Dr. Elmer Cranton is a paperback book that
provides the layman with an excellent source of information about
EDTA chelation therapy.

For a list of physicians who use chelation therapy, send a self-
addressed, stamped envelope (58 cents) to:

      American College for the Advancement of Medicine
      23121 Verdugo Drive, Suite 204
      Laguna Hills, CA 92653

Physicians who care to learn more about EDTA chelation therapy for
atherosclerotic diseases can write to the same address, and request
copies of published clinical data. Much of this data is from studies
presently being sponsored by the Food and Drug Administration. In
addition, physicians will be provided a copy of the classic study
published in 1988 by James Carter, M.D. and Efrain Olszewer, M.D.

Chelation therapy has been administered to over one million patients
with cardiovascular disease. It has caused not one single fatality.

Health-care professionals who discredit chelation therapy as a viable
alternative to surgery should:

      (1) demonstrate that the published clinical data favoring
          chelation therapy has been misinterpreted;

      (2) cite a published study that discredits chelation therapy.
From: geb@dsl.pitt.edu (gordon e. banks)
Newsgroups: sci.med
Subject: Re: Suicide prevention; what next?
Date: 9 Apr 92 17:35:36 GMT
Organization: Decision Systems Laboratory, Univ. of Pittsburgh, PA.

In article <4260042@hpnmdla.sr.hp.com> kurts@hpnmdla.sr.hp.com (Kurt Strain) writes:

>
>Sorry, but a mentally ill person cannot make these decisions with a sound
>mind.  Instead, his instincts are to fight it in a paranoid state.  I and
>my twin brother both had to be dragged in against our will for treatment.
>I was told twice by my father to go in and I still refused, thinking "I
>ain't crazy, I'm just getting over some nerves here. It'll go away." Wrong!
>My dad knew better, he's seen it before with my brother.
>
If Herman had actually worked with psychotic patients rather than just
getting his information from "One Flew Over the Cuckoo's Nest" and
Thomas Szasz's books, he'd know that most psychotic patients are
very glad you treated them once they've regained their senses.  I've
also had to drag a manic friend in kicking and screaming.  Two weeks
and much lithium later, he was his old self and thanked me profusely,
while at the time he was sure I was in league with the devil for
essentially strong-arming him into the car and driving him to the
psychiatric hospital.  Many schizophrenics will recognize when they
are getting crazy and present for treatment.  But if they go too
far, they have to be coerced.  That's what I would want for myself
in the same situation, and that's what I will do for my friends.

I fail to see the difference between that and letting a patient
with a head injury who is not in his right mind walk out of the
ER.  I've had to restrain patients in that situation also.

-- 
----------------------------------------------------------------------------
Gordon Banks  N3JXP      | "I have given you an argument; I am not obliged
geb@cadre.dsl.pitt.edu   |  to supply you with an understanding." -S.Johnson
----------------------------------------------------------------------------
From: kingsley@hpwrce.HP.COM (Kingsley Morse)
Date: Tue, 14 Apr 1992 20:30:25 GMT
Subject: Re: Class action against FDA
Organization: HP Western Response Center
Newsgroups: sci.med

I got a message from Bill at the Life Extension Foundation saying that over
100 people have signed the affidavit so far. The LEF can be reached at their
800 number. Call 800-555-1212 to get their 800 phone number.
From: geb@dsl.pitt.edu (gordon e. banks)
Newsgroups: sci.med
Subject: Re: Brainless legal decisions about newborns.
Date: 8 Apr 92 22:50:01 GMT
Organization: Decision Systems Laboratory, Univ. of Pittsburgh, PA.

In article <19255@suned1.Nswses.Navy.MIL> laura@TASVAX.NSWSES.NAVY.MIL writes:
>In article <14230@pitt.UUCP>, geb@dsl.pitt.edu (gordon e. banks) writes:
>
>>the main argument against (or at least my perception of it)
>>is that this practice would be the first instance of actually
>>killing something in order to get organs for transplant.
>
>What is the status of a brain dead patient?  Is it alright to take out
>organs?  Can't these babies be classified as brain dead?  I thought 
>brain dead pretty much meant "dead".  Could it really be classified as
>"killing something in order to get organs"?
>
Brain dead means legally dead.  The heart is still beating, however.
The legal definition of brain dead in most states includes death
of the brain stem.  The brain stem is not dead in anencephalic
infants, who have a brain stem that works.  The brain stem controls
reflexes, but not cognition (thinking).  Organs can be removed
from brain dead patients if their relatives agree or if they have
a donor card signed.  Brain dead patients provide most of the
livers and all of the hearts for transplants.
If the heart stops, the patient is dead in the traditional way,
but you almost have to have the patient prepped for donor
surgery in the OR at the time or the liver  will spoil.  They've
done that in a few cases here, but it is kind of controversial.
-- 
----------------------------------------------------------------------------
Gordon Banks  N3JXP      | "I have given you an argument; I am not obliged
geb@cadre.dsl.pitt.edu   |  to supply you with an understanding." -S.Johnson
----------------------------------------------------------------------------
Newsgroups: sci.med
From: ME.DMG@forsythe.stanford.edu (David Gaba M.D.)
Subject: Re: Bernie S. Siegel
Organization: Stanford University, California, USA
Distribution: usa
Date: Tue, 7 Apr 1992 03:58:01 GMT

In article <1992Apr6.163409.11753@cc.umontreal.ca>,
gaumondp@ERE.UMontreal.CA (Gaumond Pierre) writes:
>Have you read the last book of Bernie S. Siegel: "Peace, Love and Health".
>
>He claims that while under anesthesia, the unconscious mind remains "awake",
>that is, it can respond to the suggestion of the surgeon. For example, he cited
>a case where a person having an organ transplant needed only 3 units of blood
>while about 200 units are usually needed. He said he suggested to the patient
>under anesthesia not to bleed.
>Has anyone worked with Bernie or see what he claims? Has anyone else tried the

Well, I am an anesthesiologist and yes, 14 years ago while a med.
student I did see Dr. Siegel work.  He and I did a hernia together
and he didn't make any suggestions to the patient then.

I do not believe the story of the hyponotic suggestion not to
bleed.  Sounds like a big fish story to me.

There is some evidence that parts of the brain are functioning
during anesthesia.  Of course the simplest parts controlling
basic functions are operative except in the very deepest (and
probably nearly lethal) levels of anesthesia or coma.  But it
does appear that higher functions MIGHT be somewhat intact.
  Most of this data relates to what is called  "implicit memory."
That is, if you read a list of words to a patient under anesthesia
they may not be able to remember any of them afterwards.  However,
if given a list of 40 words to pick 10 from which they "like" they
may be more likely to pick the words they heard during anesthesia.

There was recently a large review article on this topic in
ANESTHESIOLOGY (last couple of months I think).

There has been some evidence of successful post-anesthesia
suggestions being given during anesthesia.  Usually these are things
like not having nausea or pain.  There have been studies where
patients were suggested to scratch their nose or whatever.  To the
best of my knowledge, these studies have been equivocal.  It
sometimes seems to work but not always, and as I recall, it is always
a statistically valid, but not very impresssive effect (p<0.05
but maybe 6/20 in suggestion group vs. 2/20 in control group or
whatever).

So, no one can say "it never works" but I wouldn't bet the
farm on it either.

I don't have time to comment on anesthetics for psychotherapy,
but unless you are prepared to intubate and ventilate the
patient you might, once in a while, get into serious trouble!

**** THE ABOVE IS FOR INFORMATION ONLY AND DOES NOT CONSTITUTE
MEDICAL ADVICE *******************

David M. Gaba, M.D.  Asst.. Prof of Anesthesia,  Stanford Univ.
From: george@ibmpcug.co.uk (Michael Veltman)
Newsgroups: sci.med,connect.audit
Subject: Re: Input section of an EKG
Date: 16 Apr 92 15:14:38 GMT
Organization: The IBM PC User Group, UK.

12 Lead ECG

Actually has 10 leads (!)

Right arm, Right Leg, Left arm, Left leg
six chest leads (V1-V6) and may have others as well in unusual
configurations.

six tracings are taken using the other four leads as a common 
ground to get the "V" or chest leads: V1,V2,V3,V4,V5,V6

Then, Three "Bipolar" readings are taken:
"I" (roman numeral) right arm to left arm
"II"		    right arm to left leg
"III"		    left arm to left leg

Then, Three "augmented" leads are recorded,
aVL (Left arm compared to combined ground of right arm and left leg)
aVR (Right arm compared to combined ground of left arm and leg)
aVF (left leg compared to combined ground of left and right arm)

Hope this helps,

Michael

-- 
Automatic Disclaimer:
The views expressed above are those of the author alone and may not
represent the views of the IBM PC User Group.
-- 
The above opinion is not that of the IBMPCUG.
In fact, it may not be my opinion, either.

Michael Veltman         George@ibmpcug.co.uk 
Newsgroups: sci.med
From: tsf@CS.CMU.EDU (Timothy Freeman)
Subject: Re: Dentists & Doctors slaves to people with AIDS?
Date: Fri, 17 Apr 92 19:26:00 GMT
Organization: School of Computer Science, Carnegie Mellon University
	<1992Mar29.120458.12784@nmrdc1.nmrdc.nnmc.navy.mil>
	<1992Apr12.222913.28180@acsu.buffalo.edu>
	<1992Apr17.113014.2782@nmrdc1.nmrdc.nnmc.navy.mil>
Originator: tsf@U.ERGO.CS.CMU.EDU

In article <1992Apr17.113014.2782@nmrdc1.nmrdc.nnmc.navy.mil> rdc401@nmrdc1.nmrdc.nnmc.navy.mil (CDR Peter Kent) writes:

   Unfortunately, anyone who has
   studied epidemiology will immediately appreciate that there has never been a
   disease as prevalent as AIDS where the disease has been eradicated by natural
   burnout.  The only diseases that have been either totally eradicated (smallpox)
   or well controlled (tetanus) have been in cases where there was a massive
   intervention by the population at risk.

I haven't studied epidemiology.  Can you give me a reference?  (I'd
actually prefer an argument that AIDS won't go away by natural
burnout, which you didn't quite say.)

Tim

Newsgroups: sci.med
From: caf@omen.UUCP (Chuck Forsberg WA7KGX)
Subject: Re: Is cycle dieting safe?
Organization: Omen Technology INC, Portland Rain Forest
Date: Fri, 17 Apr 1992 08:30:41 GMT

In article <14392@pitt.UUCP> geb@dsl.pitt.edu (gordon e. banks) writes:
>
>We've seen it claimed by Chuch Forsberg (Adiposity 101) and others
>that dieting is dangerous, and more specifically, leads to reduced
>lean body mass and metabolism.  Rena Wing's latest paper in Am J
>Clin Nutr (55:641) has contrary evidence.  In a study (in which I
>was a participant) of 202 obese people, subjects were separated into
>quartiles with respect to cycle dieting.  Those in the 4th quartile,
>for example, had cycled an average of more than 8 times with a 
>total cumulative weight loss/gain of more than 117 kg (men) and
>14 times with weight loss/gain of more than 138 kg (women).
>In the first quartile, she had those who had never cycled,
>for the men, or only once for the women, with a loss/gain of 15 kg or
>less.  Measurements of fatness, lean body mass, blood pressure,
>cholesterol, percentage of diet from fat, and other parameters
>showed no significant differences between those who cycled and
>those who didn't for either sex. ...

Um, to quote from the paper published in the American Journal of
Clinical Nutrition 1992;55; page 642, about an inch up from
the bottom of the right hand column: "all three measures [of
diet cycling] were significantly related to BMI (P < 0.01)."

Adiposity 101 discusses the diet cycling and weight gain.
Rena's paper confirms the association between diet cycling and
weight gain with a very high confidence level.

In "Variability of Body Weight and Health Outcomes in the
Framingham Population", subjects with larger weight fluctuations
also had markedly higher BMIs and, what's worse, higher slope of
BMI (BMI/year).  (N Engl J Med 1991; 324; 1839-44)

(BMI = Body Mass Index, a measure of fatness)

If anything, these papers reinforce Adiposity 101's concerns 
about the fattening effects of diet cycling.

A National Institutes of Health conference that concluded this
month called for increased study of bad effects of dieting.

-- 
Chuck Forsberg WA7KGX          ...!tektronix!reed!omen!caf 
Author of YMODEM, ZMODEM, Professional-YAM, ZCOMM, and DSZ
  Omen Technology Inc    "The High Reliability Software"
17505-V NW Sauvie IS RD   Portland OR 97231   503-621-3406
From: eang42@castle.ed.ac.uk (L Bootland)
Newsgroups: sci.med
Subject: Re: Causing breasts to lactate
Date: 13 Apr 92 09:59:58 GMT
Distribution: sci.med
Organization: Edinburgh University


Yes a woman can lactate without having a child. Hormone treatment will
work. So will suckling. A woman who applies a breast pump to her breasts
frequently will start to lactate, as will a woman who suckles a child.
There is apparatus available which enables the child to get food during
the process. Basically, it is a container with a tube which is fixed to
the breast so that the child takes the end of the tube into its mouth
when it takes the nipple in.  Can't remember where I saw the info on
this, or where you'd get it, try mother and baby magazines.


PS. I tried mailing this but every way I tried it just bounced, unknown
address or unknown user.

L.Bootland
-- 
============================================================================
Standard disclaimer applies:   L. Bootland    eang42@castle.ed.ac.uk
                               University of Edinburgh, Genetics.



-- 
============================================================================
Standard disclaimer applies:   L. Bootland    eang42@castle.ed.ac.uk
                               University of Edinburgh, Genetics.
From: suhre@meltami.dsd.trw.com (Maurice E. Suhre)
Newsgroups: sci.med
Subject: Re: Suicide prevention; what next?
Date: 11 Apr 92 01:29:04 GMT
Organization: TRW, INC.

In article <44802@mentor.cc.purdue.edu> hrubin@pop.stat.purdue.edu (Herman Rubin) writes:
>He was a reformed alcoholic,
          ^^^^^^^^

It's not a political correctness issue, but the term should be
"recovered" or "recovering".  Remember, alcoholics aren't sinners who
need to reform (even though there may have been some very bad behavior
and they may owe a lot of emends), they are just sick people who need
to get well.

If you get super technical, the alcoholic is never "recovered" in the
sense that he/she can drink normally.  While I accept this, I don't have
any problem with recovered meaning "apparently not in danger of
drinking" and recovering meaning either "just starting out in AA" or
"being in some sort of substance abuse program, either in-patient or
out-patient".

I've unclenched my teeth :-)
-- 
Maurice Suhre
suhre@trwrb.dsd.trw.com
Newsgroups: sci.med
From: linda@frcs.Alt.ZA (Linda Jacobson)
Subject: Re: Toxoplasmosis
Organization: Onderstepoort School of Veterinary Science, University of Pretoria
Date: Fri, 17 Apr 92 11:49:54 GMT

Thus spake laura@TASVAX.NSWSES.NAVY.MIL:

> I am 5 months pregnant, and my husband and I want to get a kitten.

If you *are* going to come in contact with toxoplasmosis, the *worst* time
you could choose is during pregnancy. Many people come into contact with
toxo and develop immunity without ever developing symptoms; but the time to
do this is long before (or after) a pregnancy. 

> I intend to ask my doctor this same question, but if I take the kitten
> directly to a vet, can the vet test the kitten for toxoplasmosis?

There are tests available, but they tend to be difficult to interpret. The
best one is the Sabin Feldman, which is technicially difficult and tends
not to be done all that much. The antibody tests, commonly done, are not
reliable. A positive result may mean previous, rather than active infection;
a negative result is difficult to interpret. Oocysts in faeces are very
rarely found, so this is also not a good diagnostic test. For more details
about antibody tests, there's a recent article in Journal of Veterinary
Internal Medicine 5:299, 1992. It wasn't impressed with commercially
available tests (Toxo-Test and TPM-Test).

>  Also,
> if we keep the kitten exclusively in the house, what are the chances of the
> kitten contracting toxoplasmosis? 

The cat needs to eat an infected non-feline (almost any vertebrate can harbour
toxo) to become infected, so the chances are small if you have no mice
etc.)

> Also, what are the real dangers to
> me and my child if the cat *does* have toxoplasmosis?

Blindness in the baby is the commonest result of infection before birth.
There's not much chance you yourself will develop any clinical signs if you
are immunocompetent.

The chances of your picking up toxo from any cat are relatively small.
Personally, though, I would avoid new kittens or cats during pregnancy. It's
not worth taking the risk.

Linda
From: tas@pegasus.com (Len Howard)
Newsgroups: sci.med
Subject: Re: HPV
Date: 10 Apr 92 00:43:03 GMT
Article-I.D.: pegasus.1992Apr10.004303.24931
Followup-To: sci.med
Organization: Pegasus,  Honolulu

In article <167BE84A2.M20614@mwvm.mitre.org> M20614@mwvm.mitre.org (Hugh Pritchard) writes:
>In article <1992Apr2.194358.10172@pegasus.com>
>tas@pegasus.com (Len Howard) writes:
> 
>> ...  We only treat the localized manifestations....the papilloma or
>> wart.
> 
>Are we speaking of condylomata acumunata ("venereal warts") here?
> 
>**  Hugh Pritchard,  hapritch@mitre.org,  703/883-6616

Yes, and also the manifestation of condyloma planum that we often see
on the cervix at colposcopy.  Most people associate venereal warts
with the filiform warts on the penis or perineum, or in the vagina,
but the HPV can also cause the flat wart on the cervix which also may
be associated with an increased incidence of cervical cancer.

Len Howard,  tas@pegasus.com