From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.norvegicus GHF1 gene, exon 3,4
Date: 30 Jul 92 10:02:21 GMT
Distribution: bionet
Checksum: 26313     8

LOCUS       RATGHF13     4488 bp ds-DNA             ROD       30-JUL-1992
DEFINITION  R.norvegicus GHF1 gene, exon 3,4
ACCESSION   X65367
KEYWORDS    GHF-1 gene; GHF-2 gene; POU-domain protein; pit-1 gene;
            pituitary specific transcription factor.
SOURCE      Rattus norvegicus DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 4488)
  AUTHORS   Theill,L.E.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 2009 to 2253; 4138 to 4314)
  AUTHORS   Theill,L.E., Hattori,K., Lazzaro,D., Castrillo,J.L. and Karin,M.
  TITLE     Differential splicing of the GHF1 primary transcripts gives rise to
            two functionally distinct homeodomain proteins
  JOURNAL   EMBO J. 11, 2261-2269 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=adult; *source: tissue=pituitary tumour; *source:
            chromosome=16; *source: is_germline=Y;
            See also X65364-8, X53660 & Bodner M. et al, Cell 55:505-518(1988)
            From EMBL    entry RNGHF13;  dated 15-JUN-1992.
FEATURES             Location/Qualifiers
     intron          <1..2017
                     /number=2
     exon            2019..2243
                     /number=3
                     /usedin=X65364:ghf1_cds
                     /usedin=X65364:ghf1_mrna
                     /usedin=X65364:ghf2_cds
                     /usedin=X65364:ghf2_mrna
     intron          2244..4138
                     /number=3
     exon            4140..4304
                     /number=4
                     /usedin=X65364:ghf1_cds
                     /usedin=X65364:ghf1_mrna
                     /usedin=X65364:ghf2_cds
                     /usedin=X65364:ghf2_mrna
     intron          4305..>4488
                     /number=4
BASE COUNT     1353 a    830 c    806 g   1377 t    122 others
ORIGIN
        1 gaattcagtt cgtgtgacta ctgtgtactt aagacagctc ctaatctgaa gggaagttaa
       61 tgattacttt ataagagacc tcctaaattg gaatcagggg gaagatatat atcccgtcct
      121 tcctaactca tttagtttta tataaaaagg aggctgacta gcatgaaatt gacactttta
      181 aatggaccta tgtacctcag gcatgtgtgg gctcaaagaa ttgaaaataa tggccaggtt
      241 cttcacaatc agatcatgga gcatcattct tattgaaaga taaccagaaa tctactttac
      301 tggataattt gcatttataa aagcagaggc agagtacatt tttagcaaga aaatagttct
      361 ctcttggggt ggagagatgg ctcagtggtt tatgcatttg ctgttcttgt aaagtaaagg
      421 accaaagaat ggttttccag actcacatgg tggttcacaa ccatctctga ccccagttcc
      481 agaggagcaa cgctctctgc tggcatccac agtgtgagac atgtagtaca tgtgataagc
      541 acacacacac acacacacac acagggcaca cacacacaca cacacaaatc taaagagaaa
      601 aggatagttt ctcttaacct tttatcacac ctgtggagta tgagtttant tcatgctatt
      661 tcatttaaac tcttaaaatt gacatgttta ttttcattag aaaaaataat gtattttatt
      721 ggatagagat gaatttacca tttcttatat aaataagcta ataacttgct gacttacact
      781 acttttatta ttaaatattt atatattgtt ggaagctttt tgcattatat attactaatt
      841 gctttaattt atgggtgaag ttgagggtta ttaatttttt aatatgtttc tgagaataaa
      901 tattgtgtgt aatcaatgaa agttgctttt aagtatttat actcaggaga ctaatcaatt
      961 actcagattt ttgtgataca tgacattaaa atgaacagaa gtgaaatcct caataataaa
     1021 aatagtaatt ggcaatgaag aaaaggtgaa acaaaatatg atgaaggttt tttgtgtgca
     1081 tcctgacatt aagatcctga actgaggtct aatctagttt tcaaataaca ctgaaacttg
     1141 taaaaggtcc acagtagtcc tatttactag gacatactgc agcgaagtca agccaacact
     1201 gcacactaca gatatcccct ctagaattgg ggtctagaat tatcccctcc tttggatttt
     1261 atgtttgctt ttctttacac attacgaaaa aagaaactga ttccatcgta gtgtctactt
     1321 tttaaaaagc ttttcacaaa attttataga gcttctaagc ttaccttttg tttcttgact
     1381 catgaaatca gcttaaaaaa aaagtttgtc tttgttgtgt ttaaaatcat gctcattttc
     1441 actctgaagt taagcattta cgatcaaacc agtgatattt gtagtacttt aaggttaatt
     1501 tcccagttat aagaatttat ctgtgtagca tgcagtccaa ctatgctctt ttcttgactg
     1561 tagccactta ctaacttaga ggacagagat cagtgcacga tatctggtta gccacgtgtc
     1621 agaactcagg actgcatatt gttttacaag aaaatggaat cttatacact cgctatttaa
     1681 gatctttctc ctcctttgac attaactttg gctttgtttt cagggaaagg cggaaggtaa
     1741 tttcatttca ttccacctac tctggcttct actttaggag actgagctta aggtaacttg
     1801 taaaagctaa gaccgaatca gtgttgcaac acaagtgatc ggagtatctg ggagaatgag
     1861 ggatcagagt tagaagctca tgggcagcct gggcatatga ccaagtcctg ccttcagacg
     1921 aaactcggaa ttgttgtcaa gagcactggg atcgaacaca gtgttgttgt ataaacagac
     1981 ataatttcca accatccttt cctctctctt tctgacaggc actttaaccc cttgtcttta
     2041 caagtttcca gaccacaccc tgagtcatgg gtttcctccc ctgcaccaac ctctgctggc
     2101 ggaggaccca acagcctctg aatttaagca ggaactcagg cggaaaagta aattggtgga
     2161 agagccaata gacatggact ccccggaaat ccgagaactg gagcagtttg ccaacgaatt
     2221 taaagtgaga agaattaagt taggtacgcc tttgttgact gtgacgatca aacaatttca
     2281 tctgcaaatc cttactctag ttactgtgaa tttgttctac tttncttcaa agctcgagcc
     2341 atttctcatt ccgtatctct cctgtgcact taatctagtc caagtaggac aactaaaaca
     2401 aacaaattct taacaggata aaagcactga tttttaagtt aatgttactt cctaaaattt
     2461 agcatactca tgattagctt taaagtgctc cttttattta atatctcctt gaacaggaga
     2521 tacttcgtca taggatctga aatgatgaaa tactctaaat cgttacactg tcatcgtcgt
     2581 cgtcttcttc ttctcctcct cctccttccn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnng atatcttaaa cctctataag caactgccta
     2761 ttcttttgtg catgcatatt ttggagcaca ttttaagggc tcacttggtg tatctattaa
     2821 ctgccagctt ataaatataa atacactagt ttttaacttg gccttttaca tccttttaat
     2881 ctcttagtaa taaaaacaac tcacacttgg tgactctaga aatgcatttg tgcactatat
     2941 gaactgtgag aacagaacat gttagtgcca gatcagtgat taaacagtga catgtttaat
     3001 agacactgtc acagtcctct ttactggatt tcaccactac aaacacctct gtttcagccc
     3061 agggaaatga caagacagaa ctaagtaaaa aacactgacg gtcagtggga tcttttgaat
     3121 cctaaaaggc agtgactctg tagtgtggtt cactcaaaat gttaaatttt cactttaaat
     3181 taaattgtta tttgtcccgt tcggtaacca tttgtagttc cttttctctg aactgcctat
     3241 tcaaagtcgc ttttcatttc tactgaaaag tatttttaaa atacaataat cacgacaatt
     3301 actcgtggtt caaattcatg aaaaatgtat tttttaatag gttggaatga aggcaatcct
     3361 ctgaacttgt ggtaatttat agtgacatcc actgatgata ttgtaagcca tcatattata
     3421 catagaggta tatagccgta ggccgacata agatgtaatg acgacatggg gaaaaacagc
     3481 aggaggtgcc atatcacact tatttccagt cctgcttata tccttatgga tgcttaaaat
     3541 tgtgtgttga tggcttatta aactttatag tctagaactc tttgtggcaa tcgataagga
     3601 ccttttgttg ggggacagat gtattaccaa gtatagtaaa tgcatggagt catggactta
     3661 tgcataaaat gtgataccat agacagcctt cgaatgacat gtttgaaggt gaagtaagcc
     3721 tcagtcttag ttttattgtg taacaacata ttgttgagat ttttattctc atataaaacc
     3781 atatggtcta tcactgtgca ttttgccaaa tcgataggtc aaatattttg agcaggtatc
     3841 atatttgata atcataaaaa catcaggaat ttctaggatc attataaagt gttaggtcat
     3901 actcatgact gttcagtgtt actgtcatgt gcacacatag tccctttcac ctgaacagtg
     3961 atgcactaac cggaaggcac agtttatgga ctttgcaaat ccattctaaa tctagatgag
     4021 tctaaattgt caacaaaaga atttttagag agcaattcac aaagatccaa cgtgtgtgaa
     4081 atggaccccc gctgatcttc ctgttgaagt tggagctaat gtctcttccc ctctcacagg
     4141 atacacccag acaaacgtgg gcgaagctct ggccgctgtc cacggctccg aattcagtca
     4201 aacaaccatc tgccgatttg aaaacttgca gctcagtttc aaaaatgctt gcaaactgaa
     4261 agcaatttta tccaagtggc tggaggaagc tgagcaggtc ggaggtactg aagcaccttc
     4321 ctcagcctgt ctgtggtgtg gccactaaca acccaccagg gtgacagaat gtgtgctagc
     4381 cagggggttc agaggcttct taaccctttc aaatgaaaac taaatgtctt ggtgaatagg
     4441 gagaaaacaa tgtagtataa gtaagtatag aaataaatgc atggatcc
//