From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens arylsulphatase A mRNA, complete cds.
Date: 8 Jan 93 05:47:07 GMT
Distribution: bionet
Checksum: 34801 5

LOCUS       HUMARYA      2022 bp ss-RNA             PRI       07-JAN-1993
DEFINITION  Homo sapiens arylsulphatase A mRNA, complete cds.
ACCESSION   X52151 J04442 J04593
KEYWORDS    arylsulphatase.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Stein,C., Gieselmann,V., Kreysing,J., Schmidt,B., Pohlmann,R.,
            Waheed,A., Meyer,H.E., O'Brien,J.S. and von Figura,K.
  TITLE     Cloning and expression of human arylsulfatase A
  JOURNAL   J. Biol. Chem. 264, 1252-1259 (1989)
  STANDARD  full automatic
COMMENT     [2] revises [1]. Draft entry and computer-readable sequence for [1]
            kindly provided by C.Stein, 19-DEC-1988; for [2] by J.Kreysing,
            16-MAY-1990.
               From EMBL    entry HSARYA;  dated 01-DEC-1992.
FEATURES             Location/Qualifiers
     mRNA            <1..2005
                     /gene="ARSA"
     sig_peptide     364..417
                     /codon_start=1
     mat_peptide     418..1879
                     /product="arylsulfatase"
                     /gene="ARSA"
                     /codon_start=2
     polyA_signal    1977..1982
     CDS             353..1882
                     /gene="ARSA"
                     /product="arylsulfatase precursor"
                     /codon_start=1
                     /translation="MSMGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHP
                     SSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGL
                     PLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQN
                     LTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQD
                     RPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEET
                     LVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELAS
                     SLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVR
                     TGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGA
                     TPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPH
                     A"
BASE COUNT      313 a    705 c    613 g    391 t
ORIGIN      
        1 ccggtaccgg ctcctcctgg gctccctcta gcgccttccc cccggcccga ctgcctggtc
       61 agcgccaagt gacttacgcc cccgaccctg agcccggacc gctaggcgag gaggatcaga
      121 tctccgctcg agaatctgaa ggtgccctgg tcctggagga gttccgtccc agccctgcgg
      181 tctcccggta ctgctcgccc cggccctctg gagcttcagg aggcggccgt cagggtcggg
      241 gagtatttgg gtccggggtc tcagggaagg gcggcgcctg ggtctgcggt atcggaaaga
      301 gcctgctgga gccaagtagc cctccctctc ttgggacaga cccctcggtc ccatgtccat
      361 gggggcaccg cggtccctcc tcctggccct ggctgctggc ctggccgttg cccgtccgcc
      421 caacatcgtg ctgatctttg ccgacgacct cggctatggg gacctgggct gctatgggca
      481 ccccagctct accactccca acctggacca gctggcggcg ggagggctgc ggttcacaga
      541 cttctacgtg cctgtgtctc tgtgcacacc ctctagggcc gccctcctga ccggccggct
      601 cccggttcgg atgggcatgt accctggcgt cctggtgccc agctcccggg ggggcctgcc
      661 cctggaggag gtgaccgtgg ccgaagtcct ggctgcccga ggctacctca caggaatggc
      721 cggcaagtgg caccttgggg tggggcctga gggggccttc ctgccccccc atcagggctt
      781 ccatcgattt ctaggcatcc cgtactccca cgaccagggc ccctgccaga acctgacctg
      841 cttcccgccg gccactcctt gcgacggtgg ctgtgaccag ggcctggtcc ccatcccact
      901 gttggccaac ctgtccgtgg aggcgcagcc cccctggctg cccggactag aggcccgcta
      961 catggctttc gcccatgacc tcatggccga cgcccagcgc caggatcgcc ccttcttcct
     1021 gtactatgcc tctcaccaca cccactaccc tcagttcagt gggcagagct ttgcagagcg
     1081 ttcaggccgc gggccatttg gggactccct gatggagctg gatgcagctg tggggaccct
     1141 gatgacagcc ataggggacc tggggctgct tgaagagacg ctggtcatct tcactgcaga
     1201 caatggacct gagaccatgc gtatgtcccg aggcggctgc tccggtctct tgcggtgtgg
     1261 aaagggaacg acctacgagg gcggtgtccg agagcctgcc ttggccttct ggccaggtca
     1321 tatcgctccc ggcgtgaccc acgagctggc cagctccctg gacctgctgc ctaccctggc
     1381 agccctggct ggggccccac tgcccaatgt caccttggat ggctttgacc tcagccccct
     1441 gctgctgggc acaggcaaga gccctcggca gtctctcttc ttctacccgt cctacccaga
     1501 cgaggtccgt ggggtttttg ctgtgcggac tggaaagtac aaggctcact tcttcaccca
     1561 gggctctgcc cacagtgata ccactgcaga ccctgcctgc cacgcctcca gctctctgac
     1621 tgctcatgag cccccgctgc tctatgacct gtccaaggac cctggtgaga actacaacct
     1681 gctggggggt gtggccgggg ccaccccaga ggtgctgcaa gccctgaaac agcttcagct
     1741 gctcaaggcc cagttagacg cagctgtgac cttcggcccc agccaggtgg cccggggcga
     1801 ggaccccgcc ctgcagatct gctgtcatcc tggctgcacc ccccgcccag cttgctgcca
     1861 ttgcccagat ccccatgcct gagggcccct cggctggcct gggcatgtga tggctcctca
     1921 ctgggagcct gtgggggagg ctcaggtgtc tggagggggt ttgtgcctga taacgtaata
     1981 acaccagtgg agacttgcac atctgaaaaa aaaaaaaaaa aa
//