HDTenEightyP/NetNews huggingface dataset:
From: rlb@plex-1.ann-arbor.mi.us (Robin Billings)
Subject: Re: MAOI & shrooms
Organization: Plex-1, Michigan's Public Access Usenet Gateway  (Ann Arbor).
Date: Fri, 11 Sep 1992 15:13:55 GMT

In article <HABA.92Sep9005916@lesti.hut.fi> haba@lesti.hut.fi (Harri "Haba" Suomalainen) writes:
>In article <1992Sep6.223054.3041@csdvax.csd.unsw.edu.au> u8951608@csdvax.csd.unsw.edu.au writes:
>
>   1) substances metabolised rapidly (e.g. by MAO) before a significant 
>      concentration in the brain can develop (e.g. DMT)
>
>   I am not aware of any tryptamines in commonly used Psilocybe
>   species which would fall into category (1). MAOI could
>   possibly effect the metabolism of psilocin, and thus
>   potentiate it. 
>
>The effective substance in the shrooms is psilocin. Psilocin, however, is
>only mildly effective. Psilocin is metabolized into more potent psilocybin
>Using MAOI would slow/stop metabolism of the effective substance. Therefore,
>using MAOI would make psilocin *less* potent. 
>--

You have it backwards, psilocybin containing mushrooms generally have a
preponderance of the more stable 4-phosphoryloxy-N,N-dimethyltryptamine
(psilocybin), which the body metabolizes into 4-hydroxy-N,N-dimethyltryptamine
(psilocin) through dephosphorylation.  Psilocin is far less stable than
psilocybin, with much of the former being lost upon drying of the mushroom.
In addition, like simple N,N-dimethyltryptamine, metabolism appears to 
be carried out by deamination through the MAO system.  Thus, like DMT, 
psilocybin/psilocin are greatly potentiated by an MAO inhibitor, such
as harmine/harmaline/tetrahydroharmine, etc.  Although there are no
such inhibiting beta-carbolines in the simple mushroom, one can obtain
them from other plants, such as the stems/leaves of Banisteriopsis cappi,
the seeds/roots of Peganum harmala, and so on.  Even the mild MAO
inhibition of chocolate will potentiate the mushroom psilocybin/psilocin
resulting in a more powerful experience from a lesser dosage, as the
Mazatecan people of Oaxaca, Mexico know.  For a review of these issues,
see:

McKenna, D. J., Towers, G.H.N., & Abbott, F. (1984). Monoamine oxidase
   inhibitors in South American hallucinogenic plants: Tryptamine and
   beta-carboline constituents of ayahuasca.  _Journal_of_Ethnopharmacology_,
   10, 195-223.

McKenna, D.J., Towers, G.H.N., & Abbott, F.S. (1984). Monoamine oxidase
   inhibitors in South American hallucinogenic plants part 2: constituents
   of orally active myristicaceous hallucinogens. _Journal_of_
   Ethnopharmacology, 12, 179-211.

McKenna, D.J. & Towers, G.H.N. (1984). Biochemistry and pharmacology
   of tryptamines and beta-carbolines: A minireview.  _Journal_of_
   Psychoactive_Drugs_, 16, 347-358.

Schultes, R.E. (1982). The beta-carboline hallucinogens of South America.
   _Journal_of_Psychoactive_Drugs_, 14, 205-220.


Newsgroups: alt.drugs
From: dmh@world.std.com (David M Harmon)
Subject: New drug -- Serendipity?  What is it?
Summary:   Extra-long lasting Ecstasy?  Chemistry?  Problems?
Organization: The World Public Access UNIX, Brookline, MA
Distribution: net
Date: Sat, 12 Sep 1992 20:28:10 GMT

I have recently heard (in most unsavory connection) of a new drug
called Serendipity.  Reputedly, it produces an Ecstasy-like high
lasting several days.  Anyone know anything about what this drug
might be?  Or what problems to expect from it, over-and-above the
social problems caused by Esctasy effects?

	Dave H.

-- 
-----------------------------------------------------------------
Bad things happen to bad people, too. But we don't care as much.
					Nico of Elbows

Newsgroups: alt.drugs,talk.politics.drugs,alt.politics.usa.constitution
From: jkp@cs.HUT.FI (Jyrki Kuoppala)
Subject: Re: "War Against Drugs a Failure"
Keywords: interesting facts
Reply-To: jkp@cs.HUT.FI (Jyrki Kuoppala)
Organization: Helsinki University of Technology, Finland
Date: Tue, 15 Sep 1992 16:47:36 GMT

>     The "War on Drugs" was contrived to be a failure.

Failure?  I'm afraid you're totally mistaken here.  It's a big
success, best invention since the idea of throwing suspected witches
to water to see if they float.

//Jyrki
Newsgroups: alt.drugs
From: aankrom@nyx.cs.du.edu (Anthony Ankrom)
Subject: Re: Heroin
X-Disclaimer: Nyx is a public access Unix system run by the University
	of Denver for the Denver community.  The University has neither
	control over nor responsibility for the opinions of users.
Organization: Nyx, Public Access Unix at U. of Denver Math/CS dept.
Date: Fri, 11 Sep 92 15:53:22 GMT

In article <HABA.92Sep11011057@lesti.hut.fi> haba@lesti.hut.fi (Harri "Ha
a" Suomalainen) writes:
>In article <1992Sep9.211056.8935@mits.mdata.fi> jah@mits.mdata.fi (Jani 
. Heinonen) writes:
>
>      No, it's not any closer to the endorphins than morphine. Endorphin
 are
>   proteins (endogenous opioid peptides), morphine is an alkaloid and he
oin is
>
>In case of morphine the relevant thing to look at is distance from the
>nitrogen atom to the oxygen atom not in either -OH group. That stucture
>occurs both in methadone and in mepiridine, therefor the somewhat simila

>efects. That has been tried to copy for a new synthetic drug a long time
.
>
>Changing morphines stereochemilal structrure slighly acetylation makes
>the relevant distance different slightly. That sure has something to do
>with the change in efects!
>
>BTW, synthetic morphine would be rather easy to me, though I've not done
>it. Check out Chemical Abstacts for info on how it may be done. Not a tw

>step synthesis though..
>--
>--
>Harri Suomalainen        Harri.Suomalainen@hut.fi       haba@vipunen.hut
fi


 What? Synthetic morphine from what I have read is rather difficult to
make and probably not even worth it. If someone wants to make a synthetic
heroin then ketobemidone (an analog of meperidine, but not the one that
was tainted with MPTP). I have read that it produces one of the most
intense euphorias of the opioids. I'll have to check my reference on that.
It was somewhat dated...

St. Anthony

--
        CH3  O            CH(CH3)2        |      dadaMatrix
           >-P-S-CH2CH2-N<            VX  |                       
    CH3CH2O               CH(CH3)2        |     aankrom@nyx.cs.du.edu
                                          | A kinder gentler lobotomy...
Newsgroups: alt.drugs
From: despair@netcom.com (Scott Hanson)
Subject: Re: Heroin
Date: Tue, 08 Sep 92 20:55:22 GMT
Organization: Netcom - Online Communication Services  (408 241-9760 guest) 

In article <something> locklin@titan.ucc.umass.edu () writes:
>
>I think you are referring to something noted with respect to "speed freaks". 
>Amphetamine junkies (supposedly) have some strong BO from constant use of their
>drug of choice. Never heard of a similar effect from herion
>

It seems either the drug or a by-product is disposed of through the sweat
glands.  The smell is similar enough to the smell of speed for this to be the
case.  It does not seem to be standard "BO" but the drug itself.  This happens
quickly, one does not have to be a junkie.  There is a considerable effect on
the skin -- photosensitivity, change in complexion, prone to clogged pores,
change in odor, etc.  Any non-folklore information would be interesting.

Regards.
-- 
Scott Hanson		This has been a recording.
despair@netcom.com
From: tcederqu@sdcc13.ucsd.edu (Trevor Cederquist)
Newsgroups: alt.drugs
Subject: Re: Idea for new drug - uses no chemicals.
Keywords: electric magnetic non-chemical
Date: 4 Sep 92 22:50:34 GMT
Organization: University of California, San Diego

A Professor Donald MacCloud here at UCSD taught a perception
class I had last year.  During a lecture he took off on one 
of his trademark digressions, telling us a horrific story of 
his experimentations with this type of drugless altered state.

	He applied saline solution to the ends of his stereo
	speaker leads and PUT THEM ON HIS HEAD! (Yes, you heard
	right folks but DON'T TRY THIS AT HOME.)  He then 
	cranked the volume until he could "see" the music with
	his eyes closed.

	He did another crazy experiment with artificial sound.
	He filled his EAR with saline and then...

	Please, if you silly enough to try this at home... blame him.
 	
Trevor C. Cederquist

	
Newsgroups: alt.drugs
From: jah@mits.mdata.fi (Jani A. Heinonen)
Subject: Re: china white
Organization: Microdata International Telecomm Service, Helsinki, Finland
Distribution: alt
Date: Tue, 15 Sep 1992 06:49:34 GMT

ken.campbell@canrem.com (ken campbell) writes:

>Question: is heroin becoming "chic" again?

   Sure. One of the greatest achievements of the WoD seems to be that heroin
is getting back the glamour it lost to cocaine in the mid-1970's. Hallelujah.
-- 
Jani Heinonen                    "Tonight when I chase the dragon,
jah@mits.mdata.fi                 The water may turn to cherry wine
Finger for public PGP key         And the silver will turn to gold
E-mailed upon request             Time out of mind."
Newsgroups: alt.drugs
From: billie@camelot.bradley.edu (Eliot Frick)
Subject: Marijuana and Impotence Question
Organization: Bradley University
Date:  9 Sep 92 03:52:50 GMT


I've read the various FAQs as well as the info at the ftp site at
ftp.u.washington.edu, and I can't find anything on the relationship of
Marijuana and impotence.  I was wondering if someone could post some
information as to this subject.  Thank you.
--
"Hampton, this is the 90's.  Take out a loan and buy a clue."  -Plucky
"Rock band auditions today: Must be able to play 3 chords and grimace
musically.  See Steve Dallas."
billie@camelot.bradley.edu
Xref: sparky alt.drugs:15461 misc.legal:16981 talk.politics.drugs:6182
From: RR04@bunny.gte.com (Rob Robertson)
Newsgroups: alt.drugs,misc.legal,talk.politics.drugs
Subject: Re: Fort Wayne: Landlords Must Evict Drug-Dealing Tenants
Date: 8 Sep 92 17:56:53 GMT
Followup-To: alt.drugs
Organization: GTE Laboratories


In article <1992Sep5.154915.17558@athena.mit.edu> wdstarr@athena.mit.edu 
(William December Starr) writes:

> In article <1525@ceylon.gte.com>, 
> RR04@bunny.gte.com (Rob Robertson) said:
> 
> > What will I tell my daughter when she asks me 'how could you just
> > sit there and let it happen'? 'Well, gee honey, we tried, ya know.
> > We wrote letters to our leaders, we protested, we spoke out to
> > neighbors and friends,... I really don't know how it all happened,
> > it just kinda happened all at once, from a million different
> > directions, and by the time enough people saw it, it was too late to
> > stop it.".
> 
> Try telling her this:
> 
> "It happened because the majority wanted it.  There were a lot of us
> who saw what was happening and tried to protest, but we were
> outnumbered by the 'honest law-abiding' voters and outgunned by the
> government that they elected and supported.  Let us only hope that
> history has taught the people a lesson and that words and phrases like
> 'democracy' and 'the will of the people' and 'everybody knows that...'
> will never again carry the same terrible persuasive power that they
> did back in the dark ages."
> 
> Of course, odds are that you'll be competing for your daughter's heart
> and mind with a state-run educational system which will give as much
> mention to the atrocities of the War on Drugs as most American schools
> today give to the internment of Japanese-Americans during WWII, sigh.
> 
> -- 
> William December Starr <wdstarr@athena.mit.edu>

Or, I could tell her that democracy was just unworkable as communism, that 
if left to there own devices people will not choose to seek the truth no 
matter how uncomfortable and distasteful they may find it, but will 
instead opt for a simple, mindless life, being fed a constant stream of 
Valium, Froot Loops, and reruns of Speed Racer and Kimba... which is why, 
thankfully, the world has reverted to feudalism. Now go out there and be 
the best little serf you can be!

More likely she'll be asking someone else why I was shipped off to the 
Gulag just for writing some weird stuff and having a bunch of goofy books 
in the house.

No, this will never happen. Excuse me, I have to go now, my Froot Loops 
are getting soggy.

Rob

Rob Robertson
GTE Laboratories          (617)466-4144 vox
40 Sylvan Rd.                (617)890-9320 fax
Waltham, Mass. 02254
Would you take advice from a manic-depressive polemicist with reluctant messiah tendencies? Me neither!
Xref: sparky alt.drugs:15396 alt.suicide.holiday:2017
From: jos@and.nl (Jos Horsmeier)
Newsgroups: alt.drugs,alt.suicide.holiday
Subject: Re: A Desperate Attempt
Date: 6 Sep 92 15:52:47 GMT
Followup-To: alt.drugs
Organization: AND Software BV Rotterdam

In article <1992Sep4.070744.13921@pegasus.com> alto@pegasus.com (Andrea Ostensoe) writes:
|Well..not that desperate..it's just that there were not articles
|on ASH and well..I didni't know how else to post one.
|
|-- 
|**************************************************************************
|"I don't ask for much..just your heart on a silver platter;-)"
|						-Kali
|**************************************************************************

This is silly! Whining here on ASH. ;-) Maybe we're all just too involved
in finally _doing_ it! Planning a _real_ original way to go. No piano wires, 
no acid, no poison, no nuffin' ... just a new way to go. How 'bout this
one: eat as much chilli con carne as possible, get yourself a gasmask,
put it on, and use a lot of tape to get it firmly fixed to your face. 
Lengthen the inhale tube and stick it in an appropriate place. Tie your
hands behind your back (use hand-cuffs) and start farting. 

Do you think it'll work?

BTW what's wrong with me .sig then eh? ;-)

			Jos aka jos@and.nl
				       |
				   _-_ |
				  /_  \|
				  |    /|
				   \_-/  \
				     | | ||
				     | | ||
				   _ | | ||
				   \\ || ||
				    \\|| ||
				     \| || |
				      | |||
				      |  |
				      |  |
				      | |
				      | |
				      | |
				      | /
				      ||
				      ||

Newsgroups: alt.drugs,talk.politics.drugs
From: app45293@uxa.cso.uiuc.edu (ZUSS)
Subject: Re: "War Against Drugs a Failure"
Organization: University of Illinois at Urbana
Date: Sat, 12 Sep 1992 19:56:32 GMT
Keywords: interesting facts

hoey@husc8.harvard.edu (Steven Hoey) writes:

>[I found the article interesting, and typical of the US Government.  The
>legislature criticizes the executive, saying "no, no, no, you're doing this
>War on Drugs thing all wrong," which I agree with.  The legislature proceeds
>to tell the executive, "here, what you need to do is stop the scourge of drugs
>THIS way, with more police, and more brainwashing..."  Exchanging the devil
>we know for the devil we don't know (as well).  It's too bad the nobody in
>this brain trust can think of any other alternatives, many of which have
>been discussed here at great length.]

   It's fortunate for them that by leading the crusade of cops and guns,
the problem won't be solved.  If political problems were to be solved, they 
wouldn't have anything to accuse the other side of messing up.

-- 
 --  Tony Pulokas
     University of Illinois, Urbana/Champaign
     College of Engineering
From: atossava@kruuna.Helsinki.FI (Atro S Tossavainen)
Newsgroups: alt.drugs
Subject: 15 Reasons Why...
Date: 12 Sep 92 19:08:30 GMT
Distribution: alt
Organization: University of Helsinki

Take this with a grain of salt.. these aren't supposed to be serious.
;->

---
		15 Reasons Why Heroin Is Better Than Women

1. A heroin habit is relatively easy to kick.
2. You can stow your heroin and related paraphernalia in a locked compartment.
3. The needle vending machine usually works and doesn't require coins.
4. The heroin itself doesn't pose a risk of HIV infection.
5. Heroin is the same among all cultures.
6. When travelling with heroin, you don't have to pay its ticket.
7. You can define the purity of heroin by its colour.
8. You can go out with your heroin in your pocket.
9. You may get free samples of heroin from professionals.
10. Heroin doesn't resist when you press the bulb.
11. Heroin always comes with a rush.
12. Heroin doesn't care about your looks, as long as you have good veins.
13. You can use heroin any way you like.
14. High grade heroin is, after all, much cheaper than high grade women.
15. Heroin doesn't mind being abused.

--
Atro Tossavainen			E-mail: atossava@cc.helsinki.fi
@ University of Helsinki, Finland	Snail:	1 D 18 Sarvastonkaari
majoring in English...				SF-00840 Helsinki, Finland
at least for the time being		Voice:	+358 0 698 5043
"One can only love like a fool" - (c) Tero Valkonen
Newsgroups: alt.drugs
From: admiralq@csd4.csd.uwm.edu (Samuel Castro)
Subject: Re: When is Madison's Harvest Fest???
Organization: Computing Services Division, University of Wisconsin - Milwaukee
Date: Tue, 8 Sep 1992 05:09:32 GMT









Oops!  I gave the wrong phone number.  Dont know where I got THAT number from.  
The correct number is     608-257-HEMP

Sorry about that!

admiralq@csd4.csd.uwm.edu
Xref: sparky alt.drugs:15534 alt.society.civil-liberty:5706 talk.politics.drugs:6204
From: frazier@kona.cs.ucla.edu (Gregory Frazier)
Newsgroups: alt.drugs,alt.society.civil-liberty,talk.politics.drugs
Subject: Re: JDs (was Re: Clinton in _Rolling Stone_ ...)
Date: 9 Sep 92 19:41:05 GMT
Organization: UCLA, Computer Science Department
X-Newsreader: Tin 1.1 PL5

bill nelson (billn@hpcvaac.cv.hp.com) wrote:
: starr@genie.slhs.udel.edu (Tim Starr) writes:
: : 
: : I've excerpted the paragraph I object to in an otherwise agreeable post.
: : 
: : Absent drug prohibition, would youth gangs be able to afford automatic weapons?
: 
: Possibly. There would always be something else illegal that they could sell.
: Do they have automatic weapons, or is it a bunch of WOD hype?

Trust an Angelino - they do have automatic weapons.  So does
everybody else around here; show up on New Years, when everybody
gives their arsenal some celebratory exercise...

--
"They thought to use and shame me but I win out by nature, because a true
freak cannot be made.  A true freak must be born." - Geek Love

Greg Frazier	frazier@CS.UCLA.EDU	!{ucbvax,rutgers}!ucla-cs!frazier
From: j1moody@darwin.cc.nd.edu (Humpty Dumpty)
Newsgroups: alt.drugs
Subject: Pot Talk
Date: 9 Sep 92 05:47:44 GMT
Followup-To: alt.drugs
Organization: The Wall


What exactly do the phycho-active substances found in ganga do?

Why do some who smoke have "psychedelic" experiences while others

simply get sleepy and hungry (off the same joint)?
Xref: sparky alt.drugs:15609 talk.politics.drugs:6238
From: aankrom@nyx.cs.du.edu (Anthony Ankrom)
Subject: Re: TIHKAL?
X-Disclaimer: Nyx is a public access Unix system run by the University
	of Denver for the Denver community.  The University has neither
	control over nor responsibility for the opinions of users.
Organization: Nyx, Public Access Unix at U. of Denver Math/CS dept.
Date: Tue, 8 Sep 92 18:42:25 GMT

In article <1992Sep7.200102.6807@mits.mdata.fi> jah@mits.mdata.fi (Jani A
 Heinonen) writes:
>   Has the book come out yet? If it has, where could it be ordered from?
>If not, does anyone have any idea when it might?
>-- 
>Jani Heinonen
>jah@mits.mdata.fi
>


 It's not out yet. It should be soon. How soon is soon I don't know...

St. Anthony

--
 If mail barfs, send it to the ip #: aankrom@130.253.192.68   

                       dAdaMatriX
      I've lost my memories to all my fears...
From: jcollier@ariel.its.unimelb.EDU.AU (John Donald Collier)
Newsgroups: alt.drugs
Subject: Re: Onset Timing of Hallucinogens
Date: 11 Sep 92 08:36:53 GMT
Organization: University of Melbourne, Australia

In <1992Sep3.020047.3007@csdvax.csd.unsw.edu.au> u8951608@csdvax.csd.unsw.edu.au writes:

>Indeed, if LSD or psiloc(yb)in were taken parenterally, the onset would
>be more rapid, and could be more overwhelming. Differences occur         
>depending on the rate of diffusion of the substance from the
>blood into the brain, and this would be the limiting factor,
>determining the lag time. 

Yes, no doubt this is important, but there may be something else at
work too. LSD takes about 15 minutes to build up even when injected, 
so I hear (and I hear quite well in this case). It also takes about
15 minutes when absorbed through the skin via DMSO (again, my hearing
is good). There seems to be a 15 minute latency for some reason.

I also agree that DMT and LSD are subjectively quite distinct to the
experienced user, quite aside ffrom speed of onset.
-- 
John Collier 			Email: jcollier@ariel.ucs.unimelb.edu.au
HPS -- U. of Melbourne		  	Fax:   61+3 344 7959
Parkville, Victoria, AUSTRALIA 3052
From: u8951608@csdvax.csd.unsw.edu.au
Newsgroups: alt.drugs
Subject: Re: codeine over-the-counter
Date: 2 Sep 92 14:25:15 GMT
Organization: University of New South Wales

In article <1992Aug29.161753.27940@spdcc.com>, dyer@spdcc.com (Steve Dyer) writes:
> In article <6523@sniff.wfo.dec.com> jdw@sniff.wfo.dec.com.UUCP (Joe Whittemore) writes:
>>    In conversation the other night I was told that 'codeine' is an 'over
>>    the counter' drug in Canada. I suspect that this was in referance to
>>    some sort of codeine and aspirin. If there's someone who could clearify
>>    this for me and, if true, tell me in what province(s)/stores I'd
>>    appreciate it if they'd drop me a note via e-mail at
>>    whittemore@wfodev.enet.dec.com
> 
> 8mg of codeine with 325mg of aspirin.  Two of these might suppress
> your cough somewhat.  It is much too low a dose to be an effective
> pain reliever or to be a drug of abuse (a 150# male would require at
> least 60mg codeine for any kind of pain relief distinguishable from
> placebo.)  The aspirin in the preparation prevents too much of
> it from being taken at once.

In .au there is an OTC prep. which is 9mg codeine to 250 mg asprin.
Thus, it is possible with this to obtain a reasonable dose of
the codeine without trashing your stomach. A very commonly
prescribed pain killer is 30 mg codeine and 325 mg asprin,
which is obviously much better. Both of the above are also
sold with paracetamol instead of asprin. I have noticed useful pain
relief from 20mg of codeine up. Conversely, for severe pain,
120mg of codeine may have little effect on me (as opposed to
pethidine, etc.)

Jeremy
jeremy@rsc3.anu.edu.au
Newsgroups: alt.drugs
From: cb@wixer.cactus.org (Cyberspace Buddha)
Subject: Re: ...
Organization: Real/Time Communications
Date: Sun, 13 Sep 92 02:14:28 GMT

In article <1992Sep10.081316.29074@neptune.inf.ethz.ch> gaspar@inf.ethz.ch (gaspo) writes:
>In article <1992Sep9.163808.2673@nntp.hut.fi> jkp@cs.HUT.FI (Jyrki Kuoppala) writes:
>>In article <ADm3WhgaT6@exinco.msk.su>, ulja@exinco (ulja) writes:
>>> . 095 252-09-28,:095 255-69-82
>>
>>Hmm - Is this an ad selling Russian oregano ;-)?
>
>nah, looks like a posting from the strychnine universe got garbled on
>the downlink.  Did you try rot13'ng it? :-).
>
>--gaspo.
>

As you can see, my editor <vi> didn't like those high-ascii chars much.
I've a hunch that if you strip the high bit from that stuff, it'll be more
intelligible...  of course, considering some of the stuff I've seen on the
net, you can't be too sure...  ;)

boing,
cb

Organization: Senior, Chemistry, Carnegie Mellon, Pittsburgh, PA