From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for kinesin (heavy chain)
Date: 21 Jul 92 10:05:34 GMT
Distribution: bionet
Checksum: 50910     7

LOCUS       HUMKHCMR     3688 bp ss-RNA             PRI       21-JUL-1992
DEFINITION  H.sapiens mRNA for kinesin (heavy chain)
ACCESSION   X65873
KEYWORDS    kinesin; kinesin heavy chain.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 3688)
  AUTHORS   Navone,F., Niclas,J., Hom-Booher,N., Sparks,L., Bernstein,H.,
            McCaffrey,G. and Vale,R.D.
  TITLE     Cloning and expression of a human kinesin heavy chain gene:
            Interaction of the C-terminal domain with cytoplasmic microtubules
            in transfected CV-1 cells
  JOURNAL   J. Cell Biol. (1992) In press
  STANDARD  full automatic
COMMENT     *source: tissue=placenta; *source: clone=HK-3, HK-21, HK-H8;
            From EMBL    entry HSKHCMR;  dated 10-JUN-1992.
FEATURES             Location/Qualifiers
     CDS             314..3205
                     /product="kinesin heavy chain"
                     /codon_start=1
                     /translation="MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASK
                     PYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP
                     EGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKN
                     RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQ
                     TEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVP
                     YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE
                     LTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTV
                     DKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
                     TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQE
                     VEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIG
                     IAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEE
                     NEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHE
                     MEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKM
                     MLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHN
                     LRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADL
                     RCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARR
                     GHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGGKQV"
BASE COUNT     1317 a    694 c    839 g    838 t
ORIGIN
        1 ccagcccccg cagtccgccc agaccgtaaa gggggacgct gaggagccgc ggacgctctc
       61 cccggtgccg ccgccgctgc cgccgccatg gctgccatga tggatcggaa gtgagcatta
      121 gggttaacgg ctgccggcgc cggctcttca agtcccggct ccccggccgc ctccacccgg
      181 ggaacgcgag cgcggcgcag ctgactgctg cctctcacgg ccctcgcgac cacaagccct
      241 caggtccggc gcgttccctg caagactgag cggcggggag tggctcccgg ccgcggcccc
      301 ggctgcgaga aagatggcgg acctggccga gtgcaacatc aaagtgatgt gtcgcttcag
      361 acctctcaac gagtctgaag tgaaccgcgg cgacaagtac atcgccaagt ttcagggaga
      421 agacacggtc gtgatcgcgt ccaagcctta tgcatttgat cgggtgttcc agtcaagcac
      481 atctcaagag caagtgtata atgactgtgc aaagaagatt gttaaagatg tacttgaagg
      541 atataatgga acaatatttg catatggaca aacatcctct gggaagacac acacaatgga
      601 gggtaaactt catgatccag aaggcatggg aattattcca agaatagtgc aagatatttt
      661 taattatatt tactccatgg atgaaaattt ggaatttcat attaaggttt catattttga
      721 aatatatttg gataagataa gggacctgtt agatgtttca aagaccaacc tttcagttca
      781 tgaagacaaa aaccgagttc cctatgtaaa ggggtgcaca gagcgttttg tatgtagtcc
      841 agatgaagtt atggatacca tagatgaagg aaaatccaac agacatgtag cagttacaaa
      901 tatgaatgaa catagctcta ggagtcacag tatatttctt attaatgtca aacaagagaa
      961 cacacaaacg gaacaaaagc tgagtggaaa actttatctg gttgatttag ctggtagtga
     1021 aaaggttagt aaaactggag ctgaaggtgc tgtgctggat gaagctaaaa acatcaacaa
     1081 gtcactttct gctcttggaa atgttatttc tgctttggct gagggtagta catatgttcc
     1141 atatcgagat agtaaaatga caagaatcct tcaagattca ttaggtggca actgtagaac
     1201 cactattgta atttgctgct ctccatcatc atacaatgag tctgaaacaa aatctacact
     1261 cttatttggc caaagggcca aaacaattaa gaacacagtt tgtgtcaatg tggagttaac
     1321 tgcagaacag tggaaaaaga agtatgaaaa agaaaaagaa aaaaataaga tcctgcggaa
     1381 cactattcag tggcttgaaa atgagctcaa cagatggcgt aatggggaga cggtgcctat
     1441 tgatgaacag tttgacaaag agaaagccaa cttggaagct ttcacagtgg ataaagatat
     1501 tactcttacc aatgataaac cagcaaccgc aattggagtt ataggaaatt ttactgatgc
     1561 tgaaagaaga aagtgtgaag aagaaattgc taaattatac aaacagcttg atgacaagga
     1621 tgaagaaatt aaccagcaaa gtcaactggt agagaaactg aagacgcaaa tgttggatca
     1681 ggaggagctt ttggcatcta ccagaaggga tcaagacaat atgcaagctg agctgaatcg
     1741 ccttcaagca gaaaatgatg cctctaaaga agaagtgaaa gaagttttac aggccctaga
     1801 agaacttgct gtcaattatg atcagaagtc tcaggaagtt gaagacaaaa ctaaggaata
     1861 tgaattgctt agtgatgaat tgaatcagaa atcggcaact ttagcgagta tagatgctga
     1921 gcttcagaaa cttaaggaaa tgaccaacca ccagaaaaaa cgagcagctg agatgatggc
     1981 atctttacta aaagaccttg cagaaatagg aattgctgtg ggaaataatg atgtaaagca
     2041 gcctgaggga actggcatga tagatgaaga gttcactgtt gcaagactct acattagcaa
     2101 aatgaagtca gaagtaaaaa ccatggtgaa acgttgcaag cagttagaaa gcacacaaac
     2161 tgagagcaac aaaaaaatgg aagaaaatga aaaggagtta gcagcatgtc agcttcgtat
     2221 ctctcaacat gaagccaaaa tcaagtcatt gactgaatac cttcaaaatg tggaacaaaa
     2281 gaaaagacag ttggaggaat ctgtcgatgc cctcagtgaa gaactagtcc agcttcgagc
     2341 acaagagaaa gtccatgaaa tggaaaagga gcacttaaat aaggttcaga ctgcaaatga
     2401 agttaagcaa gctgttgaac agcagatcca gagccataga gaaactcatc aaaaacagat
     2461 cagtagtttg agagatgaag tagaagcaaa agcaaaactt attactgatc ttcaagacca
     2521 aaaccagaaa atgatgttag agcaggaacg tctaagagta gaacatgaga agttgaaagc
     2581 cacagatcag gaaaagagca gaaaactaca tgaacttacg gttatgcaag atagacgaga
     2641 acaagcaaga caagacttga agggtttgga agagacagtg gcaaaagaac ttcagacttt
     2701 acacaacctg cgcaaactct ttgttcagga cctggctaca agagttaaaa agagtgctga
     2761 gattgattct gatgacaccg gaggcagcgc tgctcagaag caaaaaatct cctttcttga
     2821 aaataatctt gaacagctca ctaaagtgca caaacagttg gtacgtgata atgcagatct
     2881 ccgctgtgaa cttcctaagt tggaaaagcg acttcgagct acagctgaga gagtgaaagc
     2941 tttggaatca gcactgaaag aagctaaaga aaatgcatct cgtgatcgca aacgctatca
     3001 gcaagaagta gatcgcataa aggaagcagt caggtcaaag aatatggcca gaagagggca
     3061 ttctgcacag attgctaaac ctattcgtcc cgggcaacat ccagcagctt ctccaactca
     3121 cccaagtgca attcgtggag gaggtgcatt tgttcagaac agccagccag tggcagtgcg
     3181 aggtggagga ggcaaacaag tgtaatcgtt tatacatacc cacaggtgtt aaaaagtaat
     3241 cgaagtacga agaggacatg gtatcaagca gtcattcaat gactataacc tctactccct
     3301 tgggattgta gaattataac ttttaaaaaa aatgtataaa ttatacctgg cctgtacagc
     3361 tgtttcctac ctactcttct tgtaaactct gctgcttccc aacacaacta gagtgcaatt
     3421 ttggcatctt aggagggaaa aaggacagtt tacaactgtg gccctattta ttacacagtt
     3481 tgtctatcgt gtcttaaatt tagtctttac tgtgccaagc taactctacc ttataggact
     3541 gtactttttg tattttttgt gtatgtttat tttttaatct cagtttaaat tacctagcta
     3601 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3661 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//