From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse APC mRNA, complete cds.
Date: 21 Jul 92 10:06:58 GMT
Distribution: bionet
Checksum: 60504    21

LOCUS       MUSAPCA      8565 bp ss-mRNA            ROD       21-JUL-1992
DEFINITION  Mouse APC mRNA, complete cds.
ACCESSION   M88127
KEYWORDS    .
SOURCE      Mus musculus (strain C57BL/6J (B6)) brain cDNA to mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 8565)
  AUTHORS   Su,L.-K., Kinzler,K.W., Vogelstein,B., Preisinger,A.C., Moser,A.R.,
            Luongo,C., Gould,K.A. and Dove,W.F.
  TITLE     Multiple intestinal neoplasia caused by a mutation in the murine
            homolog of the APC gene
  JOURNAL   Science 256, 668-670 (1992)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     CDS             1..8538
                     /product="APC"
                     /note="putative"
                     /codon_start=1
                     /translation="MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNM
                     KEVLKQLQGSIEDETMTSGQIDLLERLKEFNLDSNFPGVKLRSKMSLRSYGSREGSVS
                     SRSGECSPVPMGSFPRRTFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQL
                     QNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQRRIAR
                     IQQIEKDILRVRQLLQSQAAEAERSSQSRHDAASHEAGRQHEGHGVAESNTAASSSGQ
                     SPATRVDHETASVLSSSGTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLA
                     MSSSQDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQ
                     PDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCV
                     LMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSVTLRRYAGMALTNLTF
                     GDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGS
                     VKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQT
                     NTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTL
                     WNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANI
                     MSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQNLYGDYA
                     FDANRHDDSRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGI
                     GLSAYHPTTENAGTSSKRGLQITTTAAQIAKVMEEVSAIHTSQDDRSSASTTEFHCVA
                     DDRSAARRSSASHTHSNTYNFTKSENSNRTCSMPYAKVEYKRSSNDSLNSVTSSDGYG
                     KRGQMKPSVESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYS
                     DEQLNSGRQSPSQNERWARPKHVIEDEIKQNEQRQARSQNTSYPVYSENTDDKHLKFQ
                     PHFGQQECVSPYRSRGTSGSETNRMGSSHAINQNVNQSLCQEDDYEDDKPTNYSERYS
                     EEEQHEEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDISSSQKPSFSFSKNSSAQS
                     TKPEHLSPSSENTAVPPSNAKRQNQLRPSSAQRNGQTQKGTTCKVPSINQETIQTYCV
                     EDTPICFSRCSSLSSLSSADDEIGCDQTTQEADSANTLQTAEVKENDVTRSAEDPATE
                     VPAVSQNARAKPSRLQASGLSSESTRHNKAVEFSSGAKSPSKSGAQTPKSPPEHYVQE
                     TPLVFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSK
                     TPPPPPQTVQAKREVPKSKVPAAEKRESGPKQTAVNAAVQRVQVLPDVDTLLHFATES
                     TPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPEESNENQDKEV
                     EKPDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPVARKPSQL
                     PVYKLLPAQNRLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELA
                     TGDGVRAGIQSGEFEKRDTIPTEGRSTDDAQRGKISSIVTPDLDDNKAEEGDILAECI
                     NSAMPKGKSHKPFRVKKIMDQVQQASSTSSGANKNQVDTKKKKPTSPVKPMPQNTEYR
                     TRVRKNTDSKVNVNTEETFSDNKDSKKPSLQTNAKAFNEKLPNNEDRVRGTFALDSPH
                     HYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKESKDSEAKVTCRPEPNS
                     SQQAASKSQASIKHPANRAQSKPVLQKQPTFPQSSKDGPDRGAATDEKLQNLAIENTP
                     VCFSRNSSLSSLSDIDQENNNNKESEPIKEAEPANSQGEPSKPQASGYAPKSFHVEDT
                     PVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKRPSRLKSESEKQSPRKVGGILAED
                     LTLDLKDLQRPDSEHAFSPGSENFDWKAIQEGANSIVSSLHQAAAAAACLSRQASSDS
                     DSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLEAKKIESENKGIKG
                     GKKVYKSLITGKIRSNSEISSQMKQPLPTNMPSISRGRTMIHIPGLRNSSSSTSPVSK
                     KGPPLKTPASKSPSEGPGATTSPRGTKPAGKSELSPITRQTSQISGSNKGSSRSGSRD
                     STPSRPTQQPLSRPMQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKM
                     SYTSPGRQLSQQNLTKQASLSKNASSIPRSESASKGLNQMSNGNGSNKKVELSRMSST
                     KSSGSESDSSERPALVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAQ
                     TPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYNDGRPTKRHDIARSHSESPSR
                     LPINRAGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDERHVSSMP
                     APRQMKENQVPTKGTWRKIKESDISPTGMASQSASSGAASGAESKPLIYQMAPPVSKT
                     EDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGSSSIKDSKDSKDTHGKQSVGSG
                     SPVQTVGLETRLNSFVQVEAPEQKGTEAKPGQSNPVSIAETAETCIAERTPFSSSSSS
                     KHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVSTNTKKRDSKTDITESS
                     GAQSPKRHSGSYLVTSV"
     allele          358
                     /type="castaneous"
                     /note="replace(358,g)"
                     /gene="APC"
     allele          402
                     /type="castaneous"
                     /note="replace(402,a)"
                     /gene="APC"
     allele          714
                     /type="castaneous"
                     /note="replace(714,a)"
                     /gene="APC"
     allele          1477
                     /type="castaneous"
                     /note="replace(1477,a)"
                     /gene="APC"
     allele          2390
                     /type="castaneous"
                     /note="replace(2390,t)"
                     /gene="APC"
     allele          2409
                     /type="castaneous"
                     /note="replace(2409,g)"
                     /gene="APC"
     mutation        2549
                     /phenotype="multiple intestinal neoplasia"
                     /type="Min"
                     /note="replace(2549,a)"
                     /gene="APC"
                     /citation=[1]
     allele          2613
                     /type="castaneous"
                     /note="replace(2613,t)"
                     /gene="APC"
     allele          2718
                     /type="castaneous"
                     /note="replace(2718,c)"
                     /gene="APC"
     allele          3297
                     /type="castaneous"
                     /note="replace(3297,g)"
                     /gene="APC"
     allele          3819
                     /type="castaneous"
                     /note="replace(3819,c)"
                     /gene="APC"
     allele          3988
                     /type="castaneous"
                     /note="replace(3988,a)"
                     /gene="APC"
     allele          4569
                     /type="castaneous"
                     /note="replace(4569,a)"
                     /gene="APC"
     allele          4830
                     /type="castaneous"
                     /note="replace(4830,g)"
                     /gene="APC"
     allele          4852
                     /type="castaneous"
                     /note="replace(4852,t)"
                     /gene="APC"
     allele          4878
                     /type="castaneous"
                     /note="replace(4878,g)"
                     /gene="APC"
     allele          4956
                     /type="castaneous"
                     /note="replace(4956,g)"
                     /gene="APC"
     allele          5475
                     /type="castaneous"
                     /note="replace(5475,g)"
                     /gene="APC"
     allele          6057
                     /type="castaneous"
                     /note="replace(6057,c)"
                     /gene="APC"
     allele          6366
                     /type="castaneous"
                     /note="replace(6366,a)"
                     /gene="APC"
     allele          6369
                     /type="castaneous"
                     /note="replace(6369,t)"
                     /gene="APC"
     allele          6390
                     /type="castaneous"
                     /note="replace(6390,t)"
                     /gene="APC"
     allele          6420
                     /type="castaneous"
                     /note="replace(6420,t)"
                     /gene="APC"
     allele          6753
                     /type="castaneous"
                     /note="replace(6753,g)"
                     /gene="APC"
     allele          6816
                     /type="castaneous"
                     /note="replace(6816,c)"
                     /gene="APC"
     allele          6881
                     /type="castaneous"
                     /note="replace(6881,c)"
                     /gene="APC"
     allele          7188
                     /type="castaneous"
                     /note="replace(7188,a)"
                     /gene="APC"
     allele          7488
                     /type="castaneous"
                     /note="replace(7488,g)"
                     /gene="APC"
     allele          7567
                     /type="castaneous"
                     /note="replace(7567,g)"
                     /gene="APC"
     allele          7632
                     /type="castaneous"
                     /note="replace(7632,a)"
                     /gene="APC"
     allele          8112
                     /type="castaneous"
                     /note="replace(8112,c)"
                     /gene="APC"
     allele          8151
                     /type="castaneous"
                     /note="replace(8151,t)"
                     /gene="APC"
     allele          8438
                     /type="castaneous"
                     /note="replace(8438,g)"
                     /gene="APC"
     allele          8546
                     /type="castaneous"
                     /note="replace(8546,g)"
                     /gene="APC"
BASE COUNT     2767 a   2021 c   1921 g   1856 t
ORIGIN
        1 atggctgcag cttcatatga tcagttgtta aagcaagttg aggcactgaa gatggagaac
       61 tcaaatcttc gacaagagct agaagataat tccaatcatc ttacaaaact ggaaactgag
      121 gcatctaata tgaaggaagt acttaagcag ctacagggaa gtattgaaga tgagactatg
      181 acttctggac agattgactt actagagcgt cttaaagaat ttaacttaga tagtaatttc
      241 cccggagtga aactacgctc aaaaatgtcc cttcgctcct acggaagtcg ggaaggatct
      301 gtatccagcc gttcaggaga atgcagtcct gtccccatgg ggtcattccc aagaagaaca
      361 tttgtaaatg gaagcagaga gagtactggg tatctagaag agcttgaaaa agaaagatca
      421 ttactccttg ctgatcttga caaagaagag aaggaaaagg actggtatta tgctcaactt
      481 cagaacctca caaaaagaat agatagcctg cctttaactg aaaatttttc cttacagaca
      541 gacatgacaa gacggcagct ggagtatgaa gcaaggcaga tcagggctgc aatggaggag
      601 cagcttggca cctgccagga catggagaag cgtgcacagc gaagaatagc caggatccag
      661 caaatagaaa aggacatact gcgcgtgcgc cagcttttac agtcccaggc ggcggaagcg
      721 gagaggtcat ctcagagcag gcatgatgct gcctcccatg aagctggccg gcagcacgaa
      781 ggccacggag tggcagaaag caacaccgca gcctccagta gtggtcagag tccagctaca
      841 cgtgtggatc acgaaacagc cagtgttttg agttctagcg gcacgcactc tgctcctcga
      901 aggttgacaa gtcatctggg gacaaaggtg gaaatggtgt attccttgtt gtcaatgctt
      961 ggtactcatg ataaggacga tatgtcacga actttgctag ctatgtccag ctcccaagac
     1021 agctgtatat ccatgcggca gtctggatgt cttcctctcc tcatccagct tttacatggc
     1081 aatgacaaag actctgtatt gttgggaaat tcccggggca gtaaagaggc tcgggccagg
     1141 gccagtgcag cactccacaa catcattcac tcacagcctg atgacaagag aggcaggcgt
     1201 gaaatccgag tccttcatct tttggaacag atacgagctt actgtgaaac ctgttgggag
     1261 tggcaggaag cccacgaaca aggcatggac caggacaaaa acccaatgcc agctcctgtt
     1321 gagcatcaga tctgtcctgc tgtgtgtgtt ctaatgaagc tttcatttga tgaagagcat
     1381 aggcatgcaa tgaatgaact tgggggactg caggccattg cagagttatt gcaggtggac
     1441 tgtgagatgt atgggcttac taatgaccac tacagtgtta ctttaagacg gtatgctgga
     1501 atggctttga caaacttgac ctttggagat gttgccaaca aggctacgct gtgttctatg
     1561 aaaggctgca tgagagcact tgtggcccag ttaaaatctg agagtgaaga cttacagcag
     1621 gttattgcaa gtgttttgag gaatttgtct tggcgagcag atgtaaatag caaaaagacg
     1681 ttgagagaag ttggaagtgt gaaagcattg atggaatgtg ctttggaagt taaaaaggaa
     1741 tcaaccctca aaagcgtttt gagtgcctta tggaacctgt ctgcacactg cactgagaat
     1801 aaggctgaca tctgtgctgt ggatggagca ctggcatttc tggttggcac cctcacttac
     1861 cggagccaga caaatacttt agccattatt gaaagtggag gtgggatatt acggaatgtg
     1921 tccagcttga tagctacaaa cgaagaccac aggcaaatcc taagagagaa caattgccta
     1981 caaactttat tacagcactt gaaatctcac agcttgacaa tagtcagtaa tgcatgtgga
     2041 actttgtgga atctctcagc aagaaatcct aaagaccagg aagccttgtg ggacatgggg
     2101 gcagtgagca tgctcaagaa cctcattcat tccaagcaca aaatgattgc catgggaagt
     2161 gcagcagctt taaggaatct catggcaaac agacctgcaa agtataagga tgccaatatc
     2221 atgtctcccg gctcaagtct gccatccctt cacgttagga aacagaaagc tctagaagct
     2281 gagctagatg ctcagcattt atcagaaacc ttcgacaaca ttgacaacct aagtcccaag
     2341 gcctctcacc ggagtaagca gagacacaag cagaatcttt atggtgacta tgcttttgac
     2401 gccaatcgac atgatgatag taggtcagac aatttcaata ctggaaacat gactgttctt
     2461 tcaccatatt taaatactac ggtattgccc agctcttctt cctcaagggg aagtttagac
     2521 agttctcgtt ctgagaaaga cagaagtttg gagagagagc gaggtattgg cctcagtgct
     2581 taccatccaa caacagaaaa tgcaggaacc tcatcaaaac gaggtctgca gatcactacc
     2641 actgcagccc agatagccaa agttatggaa gaagtatcag ccattcatac ctcccaggac
     2701 gacagaagtt ctgcttctac caccgagttc cattgtgtgg cagacgacag gagtgcggca
     2761 cgaagaagct ctgcctccca cacacactca aacacataca acttcactaa gtcggaaaat
     2821 tcaaatagga catgctctat gccttatgcc aaagtggaat ataaacgatc ttcaaatgac
     2881 agtttaaata gtgtcactag tagtgatgga tatggtaaaa gaggccaaat gaaaccctca
     2941 gttgaatcct attctgaaga tgatgaaagt aaattttgca gttatggtca gtatccagct
     3001 gacctagccc ataagataca cagtgcaaat catatggatg ataatgatgg agaactggat
     3061 acaccaataa attacagtct taaatattca gatgagcagt tgaactcagg aaggcagagt
     3121 ccctcacaga atgaaaggtg ggcaagacca aagcatgtga tagaagatga aataaagcaa
     3181 aacgagcaaa gacaagcaag aagccagaac accagttatc ctgtctattc tgagaatacc
     3241 gatgacaaac acctcaaatt ccaaccacat tttggacaac aagaatgtgt ttccccatat
     3301 aggtcaaggg gaaccagtgg ttcagaaaca aatcgaatgg gttctagtca tgcaattaat
     3361 caaaatgtaa accagtctct gtgtcaggaa gatgattatg aagatgataa acctaccaac
     3421 tacagtgaac gttattctga ggaagaacaa catgaagaag aagaagagag accgacaaat
     3481 tatagcataa aatataatga agagaaacat catgtggatc agcctattga ttatagttta
     3541 aaatatgcca ctgacatttc ttcctcacaa aaaccatcat tttcattctc aaagaattca
     3601 tcagcacaaa gcactaaacc tgaacatctc tctccaagca gcgagaatac agctgtacct
     3661 ccatctaatg ccaaaaggca gaatcagctg cgtccaagtt cagcacaaag aaatggccag
     3721 actcaaaaag gcactacttg caaagtcccc tccatcaacc aagaaacaat acagacttac
     3781 tgcgtagaag acaccccaat atgtttttca aggtgcagtt cattatcatc actgtcatca
     3841 gctgacgatg aaataggatg tgatcagaca acacaggaag cagattctgc taatactctg
     3901 cagacagcag aagtaaaaga gaatgatgta actcggtcag ctgaagatcc tgcaactgaa
     3961 gttccagcag tgtcccagaa tgctagagcc aaacccagcc gactccaggc ttctggctta
     4021 tcttcagaat caaccaggca taataaagct gttgagtttt cttcaggagc caagtctccc
     4081 tccaaaagtg gtgctcagac acccaaaagt cccccagaac actatgtcca ggagactccg
     4141 ctcgtattca gcaggtgtac ttctgtcagc tcccttgaca gttttgagag tcgctccatt
     4201 gccagctctg ttcagagtga gccatgtagt ggaatggtga gtggcatcat aagccccagt
     4261 gaccttccag atagtcctgg gcagaccatg ccaccaagca gaagcaaaac ccctccacct
     4321 cctccacaga cagtgcaggc caagagagag gtgccaaaaa gtaaagtccc tgctgctgag
     4381 aagagagaga gtgggcctaa gcagactgct gtaaatgctg ccgtgcagag ggtgcaggtc
     4441 cttccagacg tggatacttt gttacacttc gccacagaaa gtactccaga cgggttttct
     4501 tgttcctcca gcctaagtgc tctgagcctg gatgagccat ttatacagaa agatgtagaa
     4561 ttaagaatca tgcctccagt tcaggaaaac gacaatggga atgaaactga atcagaacag
     4621 cctgaggaat caaatgaaaa ccaggataaa gaggtagaaa agcctgactc tgaaaaagac
     4681 ttattagatg attctgatga cgatgatatt gaaatattag aagaatgtat tatttcagcc
     4741 atgccaacaa agtcatcacg caaagccaaa aaactagccc agactgcttc aaaattacct
     4801 ccacctgtgg caaggaaacc aagtcagcta cctgtgtata aacttctgcc agcacagaat
     4861 aggctgcagg cacaaaaaca tgttagcttt acaccagggg atgatgtgcc ccgggtgtac
     4921 tgtgtagaag ggacacctat aaacttttcc acagcaacgt ctctaagtga tctgacaata
     4981 gagtcccctc caaatgaatt ggctactgga gatggggtca gagcgggtat acagtcaggt
     5041 gaatttgaaa aacgagatac cattcctaca gaaggcagaa gtacagatga tgctcagcga
     5101 ggaaaaatct catctatagt tacaccagac ctggatgaca acaaagcaga ggaaggagat
     5161 attcttgcag aatgtatcaa ttctgctatg cccaaaggaa aaagccacaa gcctttccga
     5221 gtgaaaaaga taatggacca agtccaacaa gcatcctcga cttcatctgg agctaacaaa
     5281 aatcaagtag acactaagaa aaagaagcct acttcaccag taaagcccat gccacaaaat
     5341 actgaatata gaacgcgtgt gagaaagaat acagactcaa aagttaatgt aaatactgaa
     5401 gaaactttct cagacaacaa agactcaaag aaaccaagct tacaaaccaa tgccaaggcc
     5461 ttcaatgaaa agctacctaa caatgaagac agagtgcggg ggacgttcgc cttggactca
     5521 ccgcatcact acacccctat tgaggggacg ccgtactgct tttcccgaaa tgactccttg
     5581 agttctctgg attttgatga tgacgatgtt gacctttcca gggaaaaggc cgagttaaga
     5641 aagggcaaag aaagcaagga ttccgaagcc aaagttacct gccgcccaga accaaactca
     5701 agccagcagg cagctagtaa gtcacaagcc agtataaaac atccagcaaa cagagcacag
     5761 tccaaaccag tgctgcagaa acagcccact ttcccccagt cctccaaaga cggaccagat
     5821 agaggggcag caactgacga aaaactgcag aatttagcta ttgaaaatac tccagtttgc
     5881 ttttctcgaa attcctctct gagttccctt agtgacattg accaggaaaa caacaataac
     5941 aaagaaagtg aaccaatcaa agaagctgaa cctgccaact cacaaggaga gcccagtaag
     6001 cctcaggcat ccgggtatgc tcccaagtcc ttccacgtcg aagacacccc tgtctgtttc
     6061 tcaagaaaca gctctctcag ttctcttagc attgactctg aggacgacct gttacaggag
     6121 tgtataagtt ctgccatgcc aaaaaagaaa aggccttcaa gactcaagag tgagagcgaa
     6181 aagcagagcc ctagaaaagt gggtggcata ttagctgaag acctgacgct tgatttgaaa
     6241 gatctacaga ggccagattc agaacacgct ttctcccccg gctcagaaaa ttttgactgg
     6301 aaagctattc aggaaggcgc aaactccata gtaagtagtt tgcaccaagc tgctgcagcc
     6361 gccgcgtgct tatctagaca agcgtcatcc gactcagatt ccattctgtc actaaagtcc
     6421 ggcatttctc tgggatcgcc ttttcatctt acacctgatc aagaggaaaa gccattcaca
     6481 agcaataaag gcccaagaat tctcaaacct ggagagaaaa gcacattaga agcaaaaaaa
     6541 atagaatctg aaaacaaagg aatcaaaggc gggaaaaagg tttataaaag cttgattacg
     6601 ggaaagattc gctccaattc agaaatttcc agccaaatga aacaacccct cccgacaaac
     6661 atgccttcaa tctcaagagg caggacgatg attcacatcc cagggcttcg gaatagctcc
     6721 tctagtacaa gccctgtctc taagaaaggc ccacccctca agactccagc ctctaaaagc
     6781 cccagtgaag ggccgggagc taccacttct cctcgaggaa ctaagccagc aggaaagtca
     6841 gagcttagcc ctatcaccag gcaaacttcc caaatcagtg ggtcaaataa ggggtcttct
     6901 agatcaggat ctagagactc cactccctca agacctacac agcaaccatt aagtaggcca
     6961 atgcagtctc cagggcgaaa ctcaatttcc cctggtagaa atggaataag ccctcctaac
     7021 aaactgtctc agctgcccag aacatcatct cccagtactg cttcaactaa gtcctccggt
     7081 tctgggaaaa tgtcatatac atccccaggt agacagctga gccaacaaaa tcttaccaaa
     7141 caagcaagtt tatccaagaa tgccagcagt atccccagaa gtgagtcggc atctaaagga
     7201 ctgaatcaga tgagtaacgg caatgggtca aataaaaagg tagaactttc tagaatgtct
     7261 tcaactaaat caagtggaag tgaatcagac agctcagaaa ggcctgcatt agtacgccag
     7321 tctactttca tcaaagaagc cccaagccca accctgagga ggaaactgga ggaatctgcc
     7381 tcatttgaat ccctttctcc atcttctaga ccagattctc ccaccaggtc gcaggcacag
     7441 accccagttt taagcccttc ccttcctgat atgtctctgt ccacacatcc atctgttcag
     7501 gcaggtgggt ggcgaaagct cccgcctaat ctcagcccca ctatcgagta taatgacgga
     7561 aggcccacaa aacggcatga tattgcacgc tcccattctg aaagtccttc cagactacca
     7621 atcaaccggg cgggaacctg gaagcgtgaa cacagcaaac attcctcgtc ccttcctcga
     7681 gtgagtactt ggagaagaac tggaagctca tcttctattc tttctgcttc atcagagtcc
     7741 agtgaaaaag caaaaagtga ggatgaaagg catgtgagct ccatgccagc acccagacag
     7801 atgaaggaaa accaggtgcc caccaaagga acatggagga aaatcaagga aagtgacatt
     7861 tctcccacag gcatggcttc tcagagcgct tcctcaggtg ctgccagtgg tgctgaatcc
     7921 aagcctctga tctatcagat ggcacctcct gtctctaaaa cagaggatgt ttgggtgaga
     7981 attgaggact gccccattaa caaccctaga tctggacggt cccccacagg caacaccccc
     8041 ccagtgattg acagtgtttc agagaaggga agttcaagca ttaaagattc aaaagattca
     8101 aaagacaccc atgggaaaca gagtgtgggc agtggcagtc ctgtgcaaac cgtgggtctg
     8161 gaaacccgcc tcaactcctt tgttcaggta gaggccccag aacagaaagg aactgaggca
     8221 aaaccaggac agagtaaccc agtctctata gcagagactg ctgagacgtg tatagcagag
     8281 cgtacccctt tcagttccag tagctccagc aagcacagct cacctagcgg gactgttgct
     8341 gccagagtga caccttttaa ttacaaccct agccctagga agagcagcgc agacagcact
     8401 tcagcccggc cgtctcagat ccctacgcca gtgagcacca acacgaagaa gagagattcg
     8461 aagactgaca tcacagaatc cagtggagcc caaagtccta aacgccattc cgggtcttac
     8521 ctcgtgacgt ctgtttaaaa gagctagaag gacaaacgta gaaaa
//