From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus pore-forming calcium channel alpha-1 subunit
Date: 27 Aug 92 10:00:44 GMT
Distribution: bionet
Checksum: 06654     3

LOCUS       RATCCASB      925 bp ss-mRNA            ROD       27-AUG-1992
DEFINITION  Rattus norvegicus pore-forming calcium channel alpha-1 subunit
            mRNA, partial cds.
ACCESSION   M99222
KEYWORDS    calcium channel alpha-1 subunit.
SOURCE      Rattus norvegicus (strain CD) male adult kidney, cortex cDNA to
            mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Yu,A.S., Hebert,S.C., Brenner,B.M. and Lytton,J.
  TITLE     Molecular characterization and nephron distribution of a family of
            transcripts encoding the pore-forming subunit of Ca2+ channels in
            the kidney
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. (1992) In press
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     CDS             <1..>925
                     /note="'PCR amplified splice variant of brain 'class A' or
                     'P-type' calcium channel'"
                     /product="calcium channel alpha-1 subunit"
                     /codon_start=2
                     /translation="FFHCTDESKEFERDCRGKYLLYEKNEVKARDREWKKYDFHYDNV
                     LWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSIFYVVYFVVFPFFFVN
                     IFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMPQNKQSFQYRMWQF
                     VVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLFSLECVLKVMAF
                     GILNYFRDAWNIFDFVTVLGSITDILVTEFGNPNNFINLSFLRLFRAARLIKLLRQGY
                     TIRILLWTFVQSFKALPYVCLLIAMLFFIYAI"
     misc_difference 749..754
                     /note="six bp insertion as compared to 'class A' calcium
                     channel"
BASE COUNT      204 a    266 c    213 g    242 t
ORIGIN
        1 attcttccac tgcacggacg agtccaagga gtttgagaga gactgtcgag gcaaatacct
       61 cctttacgag aagaacgagg taaaggcgcg ggaccgcgag tggaagaaat acgacttcca
      121 ctacgacaac gtgctctggg ccctgctcac gctctttacg gtgtccacgg gagagggctg
      181 gccacaggtc ctcaagcact cagtggatgc cacttttgag aaccagggcc ccagccccgg
      241 gtaccgcatg gaaatgtcca tcttctacgt ggtctacttt gtggtgtttc ccttcttctt
      301 tgtcaatatc tttgtggcct tgatcatcat caccttccag gagcagggag acaagatgat
      361 ggaagaatac agcctagaga aaaatgagag ggcctgcatc gactttgcca tcagtgccaa
      421 gccgctgacc aggcacatgc cccagaacaa gcagagcttc cagtatcgaa tgtggcagtt
      481 cgtggtgtcc ccaccctttg agtacaccat catggccatg atcgctctca acaccatcgt
      541 gctaatgatg aagttctatg gagcctctgt ggcctatgaa aacgcccttc gagtgttcaa
      601 cattgtcttc acctccctct tctctctcga atgtgtgctc aaagtcatgg cttttgggat
      661 tctgaattat ttccgcgatg cctggaacat cttcgacttt gtgactgttc tgggcagcat
      721 cacagacatc ctcgtcaccg agtttgggaa tccgaataac ttcatcaacc tgagctttct
      781 ccgcctcttc cgtgctgccc gactcatcaa actcctccgc cagggttaca ccatccgcat
      841 tctcctctgg actttcgtgc agtctttcaa ggccctacct tatgtctgtc tgctgatcgc
      901 catgctcttc ttcatctatg ccatc
//