From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse germline alpha-chain gene constant (C) region, exon 1 and 5'
Date: 6 Nov 92 18:08:02 GMT
Distribution: bionet
Checksum: 42780 4

LOCUS       MUSIGCATF    1384 bp ds-DNA             ROD       28-OCT-1992
DEFINITION  Mouse germline alpha-chain gene constant (C) region, exon 1 and 5'
            flank including 5' end of cds.
ACCESSION   L04145
KEYWORDS    alpha-immunoglobulin; beta 1-responsive element; constant region;
            germline; immunoglobulin heavy chain; transforming growth factor;
            transforming growth factor responsive element.
SOURCE      Mus musculus (strain I/St) DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (sites)
  AUTHORS   Radcliffe,G., Lin,Y.-C.A., Julius,M., Marcu,K.B. and Stavnezer,J.
  TITLE     Structure of germ line immunoglobulin alpha heavy-chain RNA and its
            location on polysomes
  JOURNAL   Mol. Cell. Biol. 10, 382-386 (1990)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   Lin,Y.-C.A. and Stavnezer,J.
  TITLE     Regulation of transcription of the germ-line immunoglobulin alpha
            constant region gene by an ATF element and by novel transforming
            growth factor beta 1-responsive elements
  JOURNAL   J. Immunol. (1992) In press
  STANDARD  full automatic
COMMENT     reference [1] reports bases 70 to 1301;reference [2] reports bases
            1 to 927.
FEATURES             Location/Qualifiers
     exon            827..1286
                     /number=1
                     /gene="IGHA"
     CDS             932..>964
                     /function="unknown"
                     /standard_name="C region"
                     /note="putative"
                     /citation=[1]
                     /gene="IGHA"
                     /product="immunoglobulin alpha-chain"
                     /codon_start=1
                     /translation="MRMDLQCGTTW"
BASE COUNT      356 a    356 c    381 g    291 t
ORIGIN      
        1 ggatccagag tcttattatc atataaatga agctcagtgg cagaggcagc ctacaaagag
       61 ggacattgtg gggaggggac agtaggatgt gtagaggatc aagtgaagag tggaacacct
      121 accctgacag tttttgaggg gccctgtagg gcaaagttcc atcctgggaa agctgtgata
      181 aggtagatgg attcaaatga gggtagcacc taactgtgac ctgcgggcct ccatgttggc
      241 cctcaggctg gggcacctac tttctgatgg aactagccat ggaggtagcc acagctcatg
      301 gccaaccatt cgagacactt gccctaccct gatgtcaacc ctgtgacctc aaagctcttc
      361 tttggggcct ccttggctta ggggcccctc tggagtagcc ctgttgctat gaagtagccc
      421 tgttgctctg gagtagccct gttgctctgg agtagccctg ttgctctgga gtagccctgt
      481 tgctctggct ccttggcaac aagctctcag gtctccctct acccttaatt gtcctctctc
      541 cctccgcatc tctgtctcag ggtctctgag caactagata gagatagatg tttatttcat
      601 tccctttctt gcatctcagg ccccaagcta cccctgtggc catgcatgtg gagtcctggc
      661 cccatcaagg cccatgtggt cagacacacc tgtctccacc acagccagac cacaggccag
      721 acatgacgtg gaggcaagcg gccacaacgt ggaggtggaa caggaagtgg gtgagggacc
      781 ccacctaggg gccagacaca cagtcatgca gccccctcag cgctcagtct gacccatcca
      841 caggcaatca cacacagaga aaaacagctt ccagccaagg cttcgcccag tcctaagctc
      901 tctaccatag ggaagatagc ctttagctat tatgagaatg gatcttcagt gtgggaccac
      961 ctggccacag gaggcctggc tgttccccta tgaaggacac tcaacagcat tgagcaggtg
     1021 ggtcccggta ccatctggac tcctctgctc attggtacac tgaggagcct caaccaggcc
     1081 aggcatggtt gagatagaga tagagataag atagaaagca ttaacaagaa ggagaaggtg
     1141 attcagggag caagagccag aggaatacag gacatgatca caggcacaag gcggtgtcgt
     1201 ctgagctgca gagaagagaa aaaaaaaaac ggatgaaacc cagcttcctg gaaagcagca
     1261 acaggagact cccaggctag acagaggcaa ggattattag gagacaacaa caaaggatgg
     1321 gggtgactca ggctgttgtg gctgagttga gctggattta gccaggctga gccgaactaa
     1381 gctt
//