From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human monoamine oxidase A (MAOA) gene, 5' end.
Date: 7 Jan 93 05:48:59 GMT
Distribution: bionet
Checksum: 61668 5

LOCUS       HUMMAOAB     1542 bp ds-DNA             PRI       06-JAN-1993
DEFINITION  Human monoamine oxidase A (MAOA) gene, 5' end.
ACCESSION   M89636
KEYWORDS    monoamine oxidase A.
SOURCE      Homo sapiens (library: Charon 35 library from ATCC) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Shih,J.C., Grimsby,J.S. and Zhu,Q.-s.
  TITLE     Promoter organization of human monoamine oxidase (MAO) A and B
            genes
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     GC_signal       complement(46..52)
     GC_signal       complement(138..145)
     repeat_region   208..237
                     /rpt_type=tandem
                     /note="putative"
     repeat_region   238..267
                     /rpt_type=tandem
                     /note="putative"
     repeat_region   268..297
                     /rpt_type=tandem
                     /note="putative"
     repeat_region   298..327
                     /rpt_type=tandem
                     /note="putative"
     repeat_region   328..342
                     /rpt_type=tandem
                     /note="This repeat contains the first (5'end) 12 bp of the
                     30 bprepeats located at 208-237, 238-267, 268-297 and
                     298-327.; putative"
     CAAT_signal     546..550
     CAAT_signal     689..693
     GC_signal       complement(735..741)
     misc_signal     795..799
                     /note="CACCC element; putative"
     misc_signal     845..852
                     /note="cAMP response element like sequence; putative"
     CAAT_signal     896..900
     misc_signal     935..939
                     /note="CACCC element; putative"
     misc_signal     945..949
                     /note="CACCC element; putative"
     CAAT_signal     1023..1027
     misc_signal     1062..1066
                     /note="CACCC element; putative"
     misc_signal     1150..1154
                     /note="CACCC element; putative"
     TATA_signal     1196..1201
     repeat_region   1211..1300
                     /rpt_type=tandem
                     /note="There is 83% homology with sequences 1301-1390.;
                     putative"
     GC_signal       complement(1227..1233)
     GC_signal       complement(1279..1286)
     repeat_region   1301..1390
                     /note="There is 83% homology with sequences 1211-1300.;
                     putative"
     GC_signal       complement(1322..1328)
                     /note="site 2"
     GC_signal       complement(1369..1376)
     CDS             1470..1542
                     /EC_number="1.4.3.4"
                     /gene="MAOA"
                     /note="exon 1 coding region; putative"
                     /product="monoamine oxidase A"
                     /codon_start=1
                     /translation="MENQEKASIAGHMFDVVVIGGGIS"
BASE COUNT      329 a    561 c    398 g    254 t
ORIGIN      
        1 ctgcagcgag cgcgggaagc gggacagggc ctagagtcac ttctccccgc ccctgactgg
       61 cccgggagcc ggggctggtc tctaagagtg ggtaccgtga acagcctgac cgtggagaag
      121 ggctgcggga agcgaaacac cgcccccagc gcccaggctg ctccagaaac atgagcacaa
      181 actgcctcag cctccttccc cggcggcacc ggcaccggca ccagtacccg caccagtacc
      241 ggcaccggca ccagtacccg caccagtacc ggcaccggca ccagtacccg caccagtacc
      301 ggcaccggca ccagtacccg caccagtacc ggcaccggca ccgagcgcaa gggcagggcc
      361 gccgaagccg gggcacaact gcccaggtcc cgaacccgga ctccagcttg gacgacacct
      421 cctacagcct gtccgaatgg agcgtccgtt ctgagtggcg gtccgtctcg gatccgctag
      481 ccagttccca gtggagcacg tcctcaactg ccgaggccgc ctcctggagc tccagcatac
      541 actccccaat cagcactacc ggtcttagcg agagtactga ctccagctgc caagagtggc
      601 ctccggggtt tcagcgctta caacccgagc agtcggatcc ccaagtctac caccagctcg
      661 aactcctccg atggggccgt cacagcctcc aatcaggaca ccggcattcc ctgggtatta
      721 gtaacaggac ctaccccgcc cgtaaactcc cccgtagagt cattgcaagg gtctgccttc
      781 tcctcagggt tcagcacccc acggggtttg gtaaaaggac cgaccctgcc cccggattcc
      841 aacctgacct cagtgtccga ctacacttgg atatttgtac ggggacctcc tatacccaat
      901 gacctttcgc aagtgtcaat acaagcacct cctacaccca gtaacacccc gagtgtagta
      961 caagggtctg cgcatcctca gtgtccagtt cccctggggt ttggtaccag gaccacctct
     1021 acccaataac agggccccag tgtcgccaca agcacctcct gcacccataa catcccccag
     1081 tgtcaaggca ggggtctacc cccacctcag tgcctgacac tccgcggggt tcaatacaag
     1141 aacctcctgc acccagtaat cctttccagc tgccgacaca aggacattct aaacctaata
     1201 actctcgccg agtgtcagta caagggtccg ccccgctctc agtgcccagc tccccccggg
     1261 tatcagctga aacatcagct ccgcccctgg gcgctcccgg agtatcagca aaagggttcg
     1321 ccccgcccac agtgcccggc tccccccggg tatcaaaaga aggatcggct ccgcccccgg
     1381 gctccccggg ggagttgata gaagggtcct tcccaccctt tgccgtcccc actcctgtgc
     1441 ctacgaccca ggagcgtgtc agccaaagca tggagaatca agagaaggcg agtatcgcgg
     1501 gccacatgtt cgacgtagtc gtgatcggag gtggcatttc ag
//