From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat mRNA for tissue factor pathway inhibitor, complete cds.
Date: 31 Dec 92 01:48:01 GMT
Distribution: bionet
Checksum: 27172 4

LOCUS       RATTFPI      1226 bp ss-mRNA            ROD       18-DEC-1992
DEFINITION  Rat mRNA for tissue factor pathway inhibitor, complete cds.
ACCESSION   D10926
KEYWORDS    TFPI; tissue factor pathway inhibitor.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda gt10 )
            liver cDNA to mRNA, clones lambda RL3 and pR3NC.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1226)
  AUTHORS   Enjyoji,K., Emi,M., Mukai,T. and Kato,H.
  TITLE     cDNA cloning and expression of rat tissue factor pathway inhibitor
            (TFPI)
  JOURNAL   J. Biochem. 111, 681-687 (1992)
  STANDARD  full automatic
COMMENT     Submitted (13-Apr-1992) to DDBJ by: Kei-ichi Enjyoji National
            Cardiovascular Center Research Institute 5 Fujishiro-dai, Suita
            Osaka 565 Japan Phone:  06-833-5012 x2472 Fax:    06-872-7485.
FEATURES             Location/Qualifiers
     sig_peptide     89..172
                     /codon_start=1
     mat_peptide     173..994
                     /product="tissue factor pathway inhibitor"
                     /codon_start=1
     polyA_signal    1205..1210
     polyA_site      1226
     CDS             89..997
                     /product="tissue factor pathway inhibitor precursor"
                     /codon_start=1
                     /translation="MTNKLKKDHAFWAAVCLLLSIVPELLNALPEEDDDTINTDSELR
                     PMKPLHTFCAMKAEDGPCKAMIRSYYFNMNSHQCEEFIYGGCRGNKNRFDTLEECRKT
                     CIPGYKKTTIKTTSGAEKPDFCFLEEDPGICRGFMTRYFYNNQSKQCEQFKYGGCLGN
                     SNNFETLEECRNTCEDPVNEVQKGDYVTNQITVTDRTTVNNVVIPQATKAPSQWDYDG
                     PSWCLEPADSGLCKASEKRFYYNPAIGKCRQFNYTGCGGNNNNFTTKQDCNRACKKDS
                     SKKSSKRAKTQRRRKSFVKVMYENIH"
BASE COUNT      402 a    242 c    256 g    326 t
ORIGIN      
        1 ggacctgtct ccggatttct tctgaagacc gtataatttt gggatctcat ctccagatct
       61 cttttgagga cgactgactc atcaagaaat gactaacaaa ctgaagaaag accacgcctt
      121 ctgggcggct gtgtgtctgc tgcttagcat tgttcctgag cttcttaatg ctctgcccga
      181 ggaagacgat gatacaataa acacagattc cgagctgcgg ccaatgaaac cgttgcatac
      241 attctgtgca atgaaggcgg aagacgggcc ctgcaaagca atgatacgga gttattattt
      301 caatatgaac agtcaccagt gtgaagaatt tatatacggg ggatgcagag gaaacaagaa
      361 ccgatttgat actctggaag agtgtaggaa aacatgcata ccaggttata aaaagacaac
      421 tataaagaca acatctggag cagaaaagcc agatttctgc ttcttggaag aggatcctgg
      481 aatctgccga ggtttcatga ccaggtattt ttataacaac cagtcaaagc agtgtgaaca
      541 attcaagtac ggcggttgcc tgggcaacag caacaacttt gagaccttgg aggagtgcag
      601 gaacacctgt gaggatccag tgaatgaggt acagaagggt gactacgtaa ctaatcaaat
      661 tactgtaact gatcgcacta ctgtaaataa cgtggtgatt cctcaggcta ccaaagcgcc
      721 cagccaatgg gactatgatg gcccttcatg gtgtcttgaa ccagcagaca gtggattatg
      781 taaagccagt gagaaaagat tctactacaa cccagccatt gggaaatgcc gtcaatttaa
      841 ctacactgga tgtgggggaa ataataataa ttttactacc aaacaagatt gtaatagagc
      901 atgtaaaaaa gattcctcca aaaaaagctc aaaaagagca aagacccaaa gaagaaggaa
      961 gtctttcgtg aaagtcatgt acgaaaatat tcattagtgc taagatataa gcacatgaca
     1021 tttttacatt agtttcacta aatattccta taaggtgttt tcactatgat ttctactctt
     1081 ctacaaacca gtttcttgtt tccattggtg accatctact ggaagatata ttttcatcgg
     1141 ttatgatcac aaacattaca tacccttgac agtctaaatc ttctctaatg attttatttt
     1201 taacaataaa atcttttatc ctgagc
//