From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Ginglymostoma cirratum MHC class II protein mRNA.
Date: 7 Jan 93 05:46:26 GMT
Distribution: bionet
Checksum: 63361 4

LOCUS       GINMHA       1186 bp ss-mRNA            VRT       06-JAN-1993
DEFINITION  Ginglymostoma cirratum MHC class II protein mRNA.
ACCESSION   M89951
KEYWORDS    alpha chain; cell surface glycoprotein; class II gene;
            integral membrane protein; major histocompatibility complex.
SOURCE      Ginglymostoma cirratum spleen cDNA to mRNA.
  ORGANISM  Ginglymostoma cirratum
            Eukaryota; Animalia; Chordata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Euselachii; Neoselachii; Batoidea;
            Orectolobiformes; Ginglymostomatidae.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Flajnik,M.F., McKinney,E.C., Sato,K., Vazquez,M. and Kasahara,M.
  TITLE     Evolution of the major histocompatibility complex: Isolation of
            class II A cDNA clones from the cartilaginous fish
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 6688-6692 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     75..134
                     /codon_start=1
     mat_peptide     135..815
                     /product="MHC class II protein"
                     /codon_start=1
     polyA_signal    1165..1170
     CDS             75..818
                     /product="MHC class II protein"
                     /codon_start=1
                     /translation="MEARNYFSVLVLVLIQGGWAGKYLYDFTQVYFVQQRSPEKHFDV
                     MEDGDEIFYMDFNLKKEVARIPEFAHLYMQGGEAAISANIAIVKNNLKVDMNLSAGTP
                     EPKVRPEVSVYSEDLVEWGQLNTLICFADGFYPPHITMKWRRNNEPMTDGDNITEFYI
                     KEDFTFRRFSYLSIVPSPGDMYSCHVEHSSLQDPVTVFWDQGVPEEKSGHGTIICALG
                     LTLGIISAVVGIILLIKERQRLQAQQHGI"
BASE COUNT      339 a    235 c    273 g    339 t
ORIGIN      
        1 gagaaacaca gcaatccaag aggagctggc actgggtgaa gactgtcgca tctcagagaa
       61 tcgagaagct cagaatggaa gcgaggaatt acttttccgt gttggtgctg gttttaattc
      121 aaggaggctg ggctggaaaa tatctgtacg atttcaccca ggtgtatttt gtgcagcagc
      181 gcagtcccga gaaacacttt gatgtgatgg aggacggaga tgagattttc tacatggact
      241 tcaacctgaa gaaggaggtg gcccggatcc ccgagtttgc ccatctttac atgcagggag
      301 gagaggcggc gatctcagcc aatatcgcca tcgtcaaaaa caatttgaaa gttgacatga
      361 acctgtccgc cgggaccccg gaaccgaaag ttcgtcctga agtctctgtg tattctgagg
      421 accttgtaga atgggggcag ctgaacacat tgatctgttt cgctgatgga ttctaccctc
      481 cacacatcac catgaagtgg agaagaaaca atgagcccat gactgatggc gataacatca
      541 ctgagttcta tattaaagag gattttacat ttcgtagatt ttcatacctg agcattgtcc
      601 cgagtcctgg agacatgtac tcctgtcatg tggaacattc gagcctacag gatccagtaa
      661 ctgtattctg ggatcaggga gttcctgagg aaaagtctgg acatgggaca ataatctgtg
      721 ctctgggact caccctggga attatcagtg ctgttgtagg aatcatctta ctgatcaaag
      781 agagacagcg gctgcaagct cagcagcatg gcatctaggg gtaccttcat tatgatgtgg
      841 aaagaaaatg cagaaaatca ctgacgttct atgctgaaac tgcaccaagt tagaaattat
      901 ttcttcattg ggttaaaatc accttatgat attatcagac ataaaccgtt tgctcaacaa
      961 tggaaatcta ccttcagatt tgtaatggat attattgtca caagtacaat gtctcttgtt
     1021 tcctaaactt caacattcat gtcatgtctt ataaaaaggc aatttgttaa tttagctgtg
     1081 gaatcctgat tgatttaaac ataatcaggg tttctcagtt tgattttcag tgttctataa
     1141 atcccttttc tatactgttg ttacaataaa tactgttaat ttcttt
//