From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Transcriptional enhancer factor DNA, complete CDS.
Date: 29 Jul 92 10:03:13 GMT
Distribution: bionet
Checksum: 25892     9

LOCUS       HUMTEF1      4443 bp ds-DNA             PRI       29-JUL-1992
DEFINITION  Transcriptional enhancer factor DNA, complete CDS.
ACCESSION   M63896
KEYWORDS    trans-acting transcriptional activator;
            transcriptional enhancer factor.
SOURCE      Homo sapiens (library: ZAP-II random primed cDNA) DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4443)
  AUTHORS   Xiao,J., Davidson,I., Matthes,H., Garnier,J.-M. and Chambon,P.
  TITLE     Cloning, expression, and transcriptional properties of the human
            enhancer factor TEF-1
  JOURNAL   Cell 65, 551-568 (1991)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     5'UTR           541..585
                     /product="transcriptional enhancer factor"
                     /gene="TEF-1"
     CDS             586..1821
                     /product="transcriptional enhancer factor"
                     /gene="TEF-1"
                     /evidence=EXPERIMENTAL
                     /codon_start=1
                     /translation="MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKII
                     LSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDK
                     ALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPF
                     VQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDS
                     YNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFW
                     ADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRF
                     VYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVF
                     EVSNSEHGAQHHIYRLVKD"
     polyA_signal    2262..2268
                     /note="potential"
                     /gene="TEF-1"
                     /note="putative"
     polyA_signal    2514..2519
                     /note="potential"
                     /gene="TEF-1"
                     /note="putative"
     polyA_signal    2581..2586
                     /note="potential"
                     /gene="TEF-1"
                     /note="putative"
     polyA_signal    2759..2764
                     /note="potential"
                     /gene="TEF-1"
                     /note="putative"
     polyA_signal    2884..2890
                     /note="potential"
                     /gene="TEF-1"
                     /note="putative"
     polyA_signal    3523..3528
                     /note="potential"
                     /gene="TEF-1"
                     /note="putative"
BASE COUNT     1226 a   1040 c    969 g   1208 t
ORIGIN
        1 cgccgcccgc cgcgggcgcc caccaagcac tttgcagact cgcttccacc ctgcgggcca
       61 ttccgcgcgg cggggcccgg gcccggggcg gccgcgtcca ggcacaggcc atgcagtgac
      121 gcccccccac ccctccacct ttgcccggac ggcgggcagc agcccagcgc gccagccggc
      181 cccggggcag gagcggtgct aggcaggggt ggggtggccg ggcccaggga ccgggagccg
      241 gggagggagc cgggcaccga gcagagggcg ggggaagcgg cgccgaagtt tgcctcggac
      301 tcgccgggcg ctgcggtggc tccctgggcc gaggactgtt gctgccgctg ccgccgccgc
      361 ttcattgcac attcaagtgg aaaattttca ggagtcagca gaaacattgt gtccaaaaaa
      421 gactgagtcg cagttaccac caaacccagg aggagactct ccctggaaaa cttcccttcc
      481 ctttcggttt attttcttga aaaggctcca ggcttcggct tggaaaatcc caccgccaaa
      541 attgagccca gcagctggag cggcagtgag agccctgccg aaaacatgga aaggatgagt
      601 gactctgcag ataagccaat tgacaatgat gcagaagggg tctggagccc cgacatcgag
      661 caaagctttc aggaggccct ggctatctat ccaccatgtg ggaggaggaa aatcatctta
      721 tcagacgaag gcaaaatgta tggtaggaat gaattgatag ccagatacat caaactcagg
      781 acaggcaaga cgaggaccag aaaacaggtg tctagtcaca ttcaggttct tgccagaagg
      841 aaatctcgtg attttcattc caagctaaag gatcagactg caaaggataa ggccctgcag
      901 cacatggcgg ccatgtcctc agcccagatc gtctcggcca ctgccattca taacaagctg
      961 gggctgcctg ggattccacg cccgaccttc ccaggggcgc cggggttctg gccgggaatg
     1021 attcaaacag ggcagccagg atcctcacaa gacgtcaagc cttttgtgca gcaggcctac
     1081 cccatccagc cagcggtcac agcccccatt ccagggtttg agcctgcatc ggccccagct
     1141 ccctcagtcc ctgcctggca aggtcgctcc attggcacaa ccaagcttcg cctggtggaa
     1201 ttttcagctt ttctcgagca gcagcgagac ccagactcgt acaacaaaca cctcttcgtg
     1261 cacattgggc atgccaacca ttcttacagt gacccattgc ttgaatcagt ggacattcgt
     1321 cagatttatg acaaatttcc tgaaaagaaa ggtggcttaa aggaactgtt tggaaagggc
     1381 cctcaaaatg ccttcttcct cgtaaaattc tgggctgatt taaactgcaa tattcaagat
     1441 gatgctgggg ctttttatgg tgtaaccagt cagtacgaga gttctgaaaa tatgacagtc
     1501 acctgttcca ccaaagtttg ctcctttggg aagcaagtag tagaaaaagt agagacggag
     1561 tatgcaaggt ttgagaatgg ccgatttgta taccgaataa accgctcccc aatgtgtgaa
     1621 tatatgatca acttcatcca caagctcaaa cacttaccag agaaatatat gatgaacagt
     1681 gttttggaaa acttcacaat tttattggtg gtaacaaaca gggatacaca agaaactcta
     1741 ctctgcatgg cctgtgtgtt tgaagtttca aatagtgaac acggagcaca acatcatatt
     1801 tacaggcttg taaaggactg aacatggtta tttatatata tagatatctg tatatacaca
     1861 cacacatatg tgcacacaca cactctctct ccattatcga acgactgact gtaaacctca
     1921 ccacacaggg tggtgccctg gccccgaggt caccccgact tttctaaatc ttgtttgagt
     1981 gaagtcattt tttcatgtgt tcatactatc attgtagctg tgaagttctg gtacagttgt
     2041 aaaaagagaa attgagttgt ttctctatgt tcttcagatg tgcagcccac aattcctcgg
     2101 gaaaggtgaa cctgaacaac ccaagtctct ctctgcagag ccctgtttct aattgtggta
     2161 gaaaatattg agacagagca tttgccatgg gacatttaca gcctttatac aaatgtattt
     2221 agttctcttt tttccaacat aaaattcttg ttttaagata caagtaaaat taatctttaa
     2281 atataaatgt aaattagtac acaaaactaa gaatctttag acttatcttt gtaactaatt
     2341 agggtggaag ttatgaaaga atgtaattca ctaaattatt ttttaaatga aacctttttt
     2401 tttctttttg aaaccaaatg ttaaactata gccttaagaa atgcttggta gaagtgtcct
     2461 aatgagacaa atttgtactt ttatcctcaa ggttaacact aatctcctaa tccattaaac
     2521 tcttgaacag gtattacaaa ggaagaaaac ttcacccctt atccttaaca tatatagtat
     2581 atttaaaaaa tataaaattg tattgtacta atgtgatgat ggattattta atgaaaaaga
     2641 aaaaatggct ctttttgcaa taagtagata catactgaaa aaatctaaac ttacaatgtt
     2701 tatagtcttg tgtgtgcagt tatattttat atggacgacc aaatttttta ttaagatgag
     2761 taaatatttg aaccactgaa ttttaataac aaaattttaa aattggcatg aatacggaat
     2821 actgcactgt gagatgcaaa gtatacagaa tctgtggctg ggagaaaatt tcatcaaata
     2881 gacaagtaaa aggctcatca gttttagcat ctctgctccc cagaaaattg taagcatcct
     2941 caccagcctg tggatacatt ctttatttct agtgacccaa tatgcatatt aacctgctat
     3001 aactagggct atatgtgtag gtatgtgtat acatatacac aaatgcacat atagagttaa
     3061 cacatttagt gaacacttgt ttagtgtcac tcagtttgct aggtgctgat atgtacgtat
     3121 atctcaatgt gtctgtagac ttagatacat cctcttgaag cacatccatt tctttagcgt
     3181 ctctcagtaa gttacagtac ttgtttgact taggtttaag aggcccagct acctatctct
     3241 gaccttttca aataggctca tttgggagat tcttttgcca ggagagattc aactttccaa
     3301 tctaagtatt ccagagcatt gcccaggcag agttggtttg atgtggccag atgttttgag
     3361 ttatttccct taagtgtttc actggggaga gaacagggag tgctcctcca gcttcccaaa
     3421 gaaatatgtt tttgtaagtg gtaggaacat gtgcacacaa tagaacatga aataagtttt
     3481 ttaacttgta aaacatgtca agatttttcc accaagctag aaaataaaaa acttagttct
     3541 accacatcca attaacttac acaccccctt ccctgtctca acacctgctt tgaccctgct
     3601 tttctattat tacatcagtc agcatcttgt ggtccctaac atgaggatgt ggctggctcg
     3661 tgggaaacag caaaacacta agcctgacct ctcccaaatt gggaagacca gaggagaaag
     3721 tgcaaaactg tccccatttg gaatgcccat tccttctaga aaccagttgg acagtgctcc
     3781 tctgcccttc ataaacagac tactgttggg tccctgattc caggctggcc tgtgaaggat
     3841 tgccccaggt gtcccctttc acggttgtca catttacagt gacttctgtt gaacacccct
     3901 cttagggatg tttcttttgc tcttatttcc tgcatctttc caattgggaa gccccatcct
     3961 ctcccaggac caggagttta tgaccaggcg agcacaaatg gctaaaagca agctgtccta
     4021 gaacttcagt gggagagctg tctggttcat attctaccca ggaatggtac ttttcagtgc
     4081 agccaggagg gctcttggga tttcctttcc aaagcacaaa aatactggga cccaagaaga
     4141 acagctagag gacaactctg ttggcacaga gacggggaca gcccagtctg ctgacctcac
     4201 agggtcagtg ggcccccctg gtgcttcacc acctgcatcc tcttgctcag aatgcctttg
     4261 cagttgagtt ttctgggttt ctatgattga ccttgaggtt tactccttgc tcttacaaca
     4321 tttctaagga tttttaaaag tttacttctt gtcttgttct tctaaagctt tctccaggac
     4381 agatattttc cctgtcttaa ccactggtcc agtcatccca gtgggcttct ctttgtctct
     4441 ccc
//