From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human T-cell receptor germline gamma-chain gene V-region (V3;
Date: 7 Jan 93 05:51:44 GMT
Distribution: bionet
Checksum: 38833 4

LOCUS       HUMTCGVA3     507 bp ds-DNA             PRI       06-JAN-1993
DEFINITION  Human T-cell receptor germline gamma-chain gene V-region (V3;
            subgroup I).
ACCESSION   M13430
KEYWORDS    T-cell antigen receptor; T-cell receptor gamma-chain; germline;
            variable region.
SEGMENT     3 of 7
SOURCE      Human B-lymphoblastoid cell line SH DNA, clone lambda-SH4.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Lefranc,M.-P., Forster,A., Baer,R.J., Stinson,M.A. and
            Rabbitts,T.H.
  TITLE     Diversity and rearrangement of the human T cell rearranging gamma
            genes: Nine germ-line variable genes belonging to two subgroups
  JOURNAL   Cell 45, 237-246 (1986)
  STANDARD  full automatic
COMMENT     Printed copy of the sequence in [1] was kindly provided by
            M.-P.Lefranc, 01-AUG-1986.  Entry revisions for [1] also kindly
            provided by M.-P. Lefranc, 22-JUN-1988.
FEATURES             Location/Qualifiers
     exon            <1..43
                     /number=1
                     /product="T-cell receptor gamma-chain"
                     /gene="TCRGV3"
                     /note="V3 region"
     intron          44..157
                     /number=1
                     /gene="TCRGV3"
     exon            158..468
                     /number=2
                     /product="T-cell receptor gamma-chain"
                     /gene="TCRGV3"
                     /note="V3 region"
     iDNA            (467.469)..>507
                     /gene="TCRGV3"
                     /note="V-J intervening DNA"
     misc_signal     469..475
                     /gene="TCRGV3"
                     /note="heptamer recombination signal; putative"
     misc_signal     499..507
                     /gene="TCRGV3"
                     /note="nonamer recombination signal; putative"
     CDS             join(<1..43,158..468)
                     /partial
                     /gene="TCRGV3"
                     /partial
                     /note="T-cell receptor gamma-chain;  (V3)"
                     /codon_start=1
                     /translation="MRWALAVLLAFLSPASQKSSNLEGRTKSVTRQTGSSAEITCDLT
                     VTNTFYIHWYLHQEGKAPQRLLYYDVSTARDVLESGLSPGKYYTHTPRRWSWILRLQN
                     LIENDSGVYYCATWDR"
BASE COUNT      128 a    120 c    124 g    135 t
ORIGIN      About 3.3 kb after segment 2; chromosome 7.
        1 atgcggtggg ccctagcggt gcttctagct ttcctgtctc ctggtgagta cgctgcctac
       61 agagaggctc acaggttggg ttttgttttg ttttcttctt gaaaggggtg ccatacaaag
      121 gaatacctca ttgtattttg tgttgttccc attgcagcca gtcagaaatc ttccaacttg
      181 gaagggagaa cgaagtcagt caccaggcag actgggtcat ctgctgaaat cacttgcgat
      241 cttactgtaa caaatacctt ctacatccac tggtacctac accaggaggg gaaggcccca
      301 cagcgtcttc tgtactatga cgtctccacc gcaagggatg tgttggaatc aggactcagt
      361 ccaggaaagt attatactca tacacccagg aggtggagct ggatattgag actgcaaaat
      421 ctaattgaaa atgattctgg ggtctattac tgtgccacct gggacaggca cagtgattca
      481 gacctgtcct acaccacact gaaaatc
//