From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Drosophila melanogaster corkscrew protein (csw) mRNA, complete cds.
Date: 18 Aug 92 10:00:37 GMT
Distribution: bionet
Checksum: 57452     9

LOCUS       DROCSW       4543 bp ss-mRNA            INV       18-AUG-1992
DEFINITION  Drosophila melanogaster corkscrew protein (csw) mRNA, complete cds.
ACCESSION   M94730
KEYWORDS    corkscrew protein; protein tyrosine phosphatase.
SOURCE      Drosophila melanogaster 0-4 hour-old embryo cDNA to mRNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 4543)
  AUTHORS   Perkins,L.A., Larsen,I. and Perrimon,N.
  TITLE     The Drosophila corkscrew gene encodes a putative protein tyrosine
            phosphatase thatppfunctions to translate the terminal signal from
            the receptor tyrosine kinase torso
  JOURNAL   Cell 70, 225-236 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     misc_feature    complement(6..84)
                     /note="SH2 domain (N terminal)"
     misc_feature    complement(111..189)
                     /note="SH2 domain (C terminal)"
     CDS             141..2666
                     /product="corkscrew protein"
                     /gene="csw"
                     /codon_start=1
                     /translation="MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLS
                     VRRGNEVTHIKIQNNGDFFDLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLI
                     CAEPTTERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVM
                     IRWQDKKYDVGGGESFGTLSELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINAR
                     VEQLVKGGFWEEFESLQQDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDVEH
                     SVAGAEYINANYIRLPTDGDLYNMSSSSESLNSSVPSCPACTAAQTQRNCSNCQLQNK
                     TCVQCAVKSAILPYSNCATCSRKSDSLSKHKRSESSASSSPSSGSGSGPGSSGTSGVS
                     SVNGPGTPTNLTSGTAGCLVGLLKRHSNDSSGAVSISMAEREREREREMFKTYIATQG
                     CLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGRSEQFGHARIQ
                     CVSENSTSDYTLREFLVSWRDQPARRIFHYHFQVWPDHGVPADPGCVLNFLQDVNTRQ
                     SHLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQ
                     RSGLVQTEAQYKFVYYAVQHYIQTLIARKRAEEQSLQVGREYTNIKYTGEIGNDSQRS
                     PLPPAISSISLVPSKTPLTPTSADLGTGMGLSMGVGMGVGNKHASKQQPPLPVVNCNN
                     NNNGIGNSGCSNGGGSSTTSSSNGSSNGNINALLGGIGLGLGGNMRKSNFYSDSLKQQ
                     QQREEQAPAGAAKFKNIPKDMIGLRPPSHAPALPPPPTPPRKT"
     misc_feature    complement(247..651)
                     /note="core PTPase domain"
                     /gene="csw"
     misc_feature    complement(290..444)
                     /note="PTPase insert"
                     /gene="csw"
BASE COUNT     1324 a   1118 c   1053 g   1048 t
ORIGIN
        1 ggtaaaaaaa taggtttttt ttttgtatcc aaccaaccaa ctgtaaaaat aagtttaaac
       61 aaagcatcta ctcataagtt tcattttttt ccgttaagtg tcaacattat ttatttttta
      121 agtgtgcatt caataagaaa atgtcatcgc gaagatggtt ccacccaacg atatctggca
      181 tcgaagctga gaaactgctg caggagcagg gattcgacgg ctccttcctc gcccgcctct
      241 cctcctcgaa tccgggcgcc ttcacgctct ccgtgcgccg cggcaacgag gtgacccaca
      301 tcaaaatcca aaacaatggc gacttctttg atctctacgg tggtgaaaag ttcgccacac
      361 tgccggaact ggtacaatac tacatggaga atggcgagct aaaggagaag aacggccagg
      421 ccatcgaact caagcagccg ctgatctgcg ccgagcccac cacggaaaga tggtttcatg
      481 gcaatctttc cggaaaggaa gcggaaaaat tgatcctgga gcggggcaag aatggttcgt
      541 ttctcgtccg tgaatctcag agcaagcctg gcgacttcgt cctttccgtg cgcacggacg
      601 acaaagtaac gcatgtcatg attcgatggc aggacaagaa gtacgacgtc ggcggcgggg
      661 aatcctttgg caccttgtcg gaactgatcg atcactacaa gcgtaatccc atggtggaga
      721 cgtgcggaac cgtggtgcat ctgcgacagc cattcaacgc cacacgaatc acggcggccg
      781 gcatcaatgc ccgggtggaa cagctggtca agggaggttt ctgggaggaa ttcgaatcgc
      841 tgcaacagga cagtcgggac acattctcgc gcaacgaggg ctacaaacag gagaaccgcc
      901 tcaagaatcg ctaccgcaac atattgccat acgaccacac gcgcgtcaag ctgctggacg
      961 tggagcatag cgtggccgga gccgagtaca tcaatgccaa ctacatacgg ctgcccaccg
     1021 acggcgacct gtacaacatg agcagctcgt cggagagcct gaacagctcg gtgccctcgt
     1081 gccccgcctg cacggctgcc cagacacagc ggaactgctc caactgccag ctgcaaaaca
     1141 agacgtgcgt gcagtgcgcc gtgaagagcg ccattctgcc gtatagcaac tgtgccacct
     1201 gcagccgcaa gtcagactcc ctgagcaagc acaagcggag cgaatcctcg gcctcttcat
     1261 cgccctcctc cggctctggg tccggaccag gatcgtcggg caccagcgga gtgagcagcg
     1321 tcaatggacc cggcacaccc accaatctca cgagcggcac agccggatgt ctggtcggcc
     1381 tgctgaagag acactcgaac gactcgtccg gagctgtttc tatatcgatg gccgaacggg
     1441 aacgcgagag ggagcgcgag atgtttaaga cctacatcgc cacccagggc tgtctgctca
     1501 cccagcaagt gaacacggtg acggacttct ggaacatggt ctggcaggag aacacgcggg
     1561 tgatcgtcat gaccaccaag gagtacgagc gcggcaaaga aaagtgcgcc cgctactggc
     1621 cggacgaggg tagatcggag cagttcggcc acgcgcggat acagtgcgtc tcggagaact
     1681 cgaccagtga ctatacgctg cgcgagttcc tcgtctcgtg gcgggatcag ccggcgcgcc
     1741 ggatctttca ctaccatttc caggtgtggc cggatcacgg agtgcccgcc gatccgggct
     1801 gtgtgctcaa cttcctgcaa gatgtcaaca cgcgtcagag tcacctggct caagcgggcg
     1861 agaagccggg tccgatctgc gtgcactgct ctgcgggcat cggtcgcact ggcaccttta
     1921 ttgtgatcga tatgattctc gatcagattg tgcgcaatgg attggatact gaaatcgaca
     1981 tccagcgcac cattcagatg gtccgatcgc agcgttccgg tcttgtgcaa accgaggcgc
     2041 aatacaagtt cgtctactat gcggtgcagc actatataca gaccctgatc gcccggaaac
     2101 gagctgagga gcagagcctg caggttggcc gcgagtacac caatataaag tacacgggcg
     2161 aaattggaaa cgattcacaa agatctccat taccaccagc aatttctagc ataagtttag
     2221 ttccgagtaa gacgccactg acgccgacat cggcggattt gggcactggg atgggcctaa
     2281 gcatgggcgt gggcatgggc gtcggcaaca agcacgcatc gaagcagcag ccgccgttgc
     2341 cggtggtcaa ctgcaacaat aataacaacg gcattggcaa tagcggctgc agcaacggcg
     2401 gcgggagcag caccaccagc agcagcaacg gcagcagcaa cggtaacatc aacgccctac
     2461 tgggcggcat cggcttgggg ctgggcggca atatgcgcaa gtcgaacttt tacagcgact
     2521 cgctgaagca gcaacagcag cgcgaggagc aggctccggc gggagcagca aaattcaaaa
     2581 acattcccaa agacatgatc ggcttgcgac cgccaagcca tgcgcctgcg ttgccgccgc
     2641 caccgacacc gccgcgcaaa acatgacaaa tgaatttcta agtcgcgacg cccccttgac
     2701 acgccccctt gacacgcccc cctgacaccc acctccctcc acacgcacac agaccacata
     2761 tggttttcat tttaaatgtc acccagccgc cgccccaaac ccaaaaccca atccctcgac
     2821 tatgttttac tgttgtacca cgttctacgt tttttttttt tttttataat tgtaatctat
     2881 atactttttt gtaattgtgt gtaatgtaat gtttagtttt atgttattgt ctcgctttat
     2941 gttgtaagtg ttccctgcac acgaaaagca gtaaccccac caccacccca aaacccaaaa
     3001 cccagcatat ttatgtagta gtattgtaag aatccccgaa ccggtagttg aggatacaat
     3061 ctgggcggaa ctgcagcaga tccgccaaaa aaacaaaaac acatttttaa gcagaatcgc
     3121 agcaacaaaa tataacaccc gttccctgtt ccaaaccgct tgaatttggt ggaatcggcc
     3181 ttgatagtat ttcactttct tgaaaatatt cgctttagat aagaaaattg acttgtgaca
     3241 aatatttaca tgtattgcgc tggttacaaa ccacaaaagt tgcttaactt taaattttac
     3301 gaatcgacat ttatgatatt tcgcatgctt gaaaatagtt gtagtttcct atttgggaat
     3361 cattgaaaaa tccatttata aagcgaaatc cagttctggc acgttcaatt tgaatcggtt
     3421 aatttctaat ctagttggcg aaaaagtgaa gaaaagtgaa gtccacctcc tccaaattca
     3481 acttgaaacg gaaacgggtt accggttgga gtgcaaataa agtttttagt gtagtaagtg
     3541 ttgacaaaat cgatagagaa gaaattagag gagtaactga ggcagtaagc acgtaacgat
     3601 aatgatacaa aaagcgttga ttgtgattcg agtgacagcg agaacagaaa ctgaaacagt
     3661 aacagtaaca gtaacagatg agaacagatg cgaatgggat cagtacagaa cagaacagaa
     3721 cagcggagac gccaaccgaa cagaacagaa atgaacagaa gagaagagaa cagattagag
     3781 gtaaaagaaa aagctaagaa gcgcttaagc gtgtcgtccc tagaataaga aaactaatat
     3841 tacagctcca cagatccaga ttcagatcca gatctatatc tctagcagcc aatttctgat
     3901 ttccccttcc ctcttagttt tcccattaat ttagtgattg tgtgtatatt tttaattgta
     3961 tattgaagat tatttatagc gattgtccat tgtgttacat ttcaaatgtt cgaaagaatt
     4021 gtatttagaa agtttgtact ttagaaatta tgcattaatt gtgtgtctgt gtctctctac
     4081 ccagtctccc tatctctgtc tctctctctc tctctccctc actgtctatg cacgagtgtt
     4141 ttcttaacta agtttattat ttcaacgctg aagcgtaatc aaactatata tgcaatattt
     4201 aagcacagta ccttgggcgc tgcaaagaaa ttaaaaaatt ttaaaataaa aacaaactgc
     4261 taaatcataa atacaaaata tatacaggaa ggaataatag cagcgaaatg taaatcaatt
     4321 agattattgt gcaaatttga gtaatatatt taaaacatac ccttatttta tcttatttaa
     4381 ctttatgctt ttgtaagtgc tttaaattgt tattcatctt gatcttgcaa aaaaatgaaa
     4441 aaaccacaaa actgaaaaac gaatacaaaa ctaaaaaaca acacaaatta tatttgtatt
     4501 tatacagaaa aataaaacat tttatatgcg aaaaaaaaaa aaa
//