From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human carboxylesterase mRNA, complete cds.
Date: 29 Dec 92 21:27:12 GMT
Distribution: bionet
Checksum: 15080 5

LOCUS       HUMCOXYSB    1966 bp ss-mRNA            PRI       14-DEC-1992
DEFINITION  Human carboxylesterase mRNA, complete cds.
ACCESSION   L07765
KEYWORDS    carboxylesterase; glycosylation-dependent.
SOURCE      Homo sapiens (library: K19) liver cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1966)
  AUTHORS   Kroetz,D.L., McBride,O.W. and Gonzalez,F.J.
  TITLE     Glycosylation-Dependent Activity of Baculovirus-Expressed Human
            Liver Carboxylesterases: cDNA Cloning and Characterization of Two
            Highly Similar Enzyme Forms
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     polyA_signal    1942..1947
     CDS             68..1768
                     /citation=[1]
                     /note="putative"
                     /product="carboxylesterase"
                     /codon_start=1
                     /translation="MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFA
                     QPVAIFLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFT
                     NRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAH
                     ENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
                     GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKT
                     TTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEE
                     LQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAK
                     ELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQY
                     RPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNP
                     NGEGLPHWPEYNQKEGYLQIGANTQAGQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL
                     "
BASE COUNT      479 a    491 c    547 g    449 t
ORIGIN      
        1 tctttcttca tccccgcatt cccaatatac ccaggccaca agagccgaga actgtcgccc
       61 ttccacgatg tggctccgtg cctttatcct ggccactctc tctgcttccg cggcttgggg
      121 gcatccgtcc tcgccacctg tggtggacac cgtgcatggc aaagtgctgg ggaagttcgt
      181 cagcttagaa ggatttgcac agcctgtggc cattttcctg ggaatccctt ttggcaagcc
      241 gcctcttgga cccctgaggt ttactccacc gcagcctgca gaaccatgga gctttgtgaa
      301 gaatgccacc tcgtaccctc ctatgtgcac ccaagatccc aaggcggggc agttactctc
      361 agagctattt acaaaccgaa aggagaacat tcctctcaag ctttctgaag actgtcttta
      421 cctcaatatt tacactcctg ctgacttgac caagaaaaac aggctgccgg tgatggtgtg
      481 gatccacgga ggggggctga tggtgggtgc ggcatcaacc tatgatgggc tggcccttgc
      541 tgcccatgaa aacgtggtgg tggtgaccat tcaatatcgc ctgggcatct ggggattctt
      601 cagcacaggg gatgaacaca gccgggggaa ctggggtcac ctggaccagg tggctgccct
      661 gcgctgggtc caggacaaca ttgccagctt tggagggaac ccaggctctg tgaccatctt
      721 tggagagtca gcgggaggag aaagtgtctc tgttcttgtt ttgtctccat tggccaagaa
      781 cctcttccac cgggccattt ctgagagtgg cgtggccctc acttctgttc tggtgaagaa
      841 aggtgatgtc aagcccttgg ctgagcaaat tgctatcact gctgggtgca aaaccaccac
      901 ctctgctgtc atggttcact gcctgcgaca gaagacggaa gaggagctct tggagacgac
      961 attgaaaatg aaattcttat ctctggactt acagggagac cccagagaga gtcaacccct
     1021 tctgggcact gtgattgatg ggatgctgct gctgaaaaca cctgaagagc ttcaagctga
     1081 aaggaatttc cacactgtcc cctacatggt cggaattaac aagcaggagt ttggctggtt
     1141 gattccaatg ttgatgagct atccactctc cgaagggcaa ctggaccaga agacagccat
     1201 gtcactcctg tggaagtcct atccccttgt ttgcattgct aaggaactga ttccagaagc
     1261 cactgagaaa tacttaggag gaacagacga cactgtcaaa aagaaagacc tgttcctgga
     1321 cttgatagca gatgtgatgt ttggtgtccc atctgtgatt gtggcccgga accacagaga
     1381 tgctggagca cccacctaca tgtatgagtt tcagtaccgt ccaagcttct catcagacat
     1441 gaaacccaag acggtgatag gagaccacgg ggatgagctc ttctccgtct ttggggcccc
     1501 atttttaaaa gagggtgcct cagaagagga gatcagactt agcaagatgg tgatgaaatt
     1561 ctgggccaac tttgctcgca atggaaaccc caatggggaa gggctgcccc actggccaga
     1621 gtacaaccag aaggaagggt atctgcagat tggtgccaac acccaggcgg gccagaagct
     1681 gaaggacaaa gaagtagctt tctggaccaa cctctttgcc aagaaggcag tggagaagcc
     1741 accccagaca gaacacatag agctgtgaat gaagatccag ccggccttgg gagcctggag
     1801 gagcaaagac tggggtcttt tgcgaaaggg attgcaggtt cagaaggcat cttaccatgg
     1861 ctggggaatt gtctggtggt ggggggcagg ggacagaggc catgaaggag caagttttgt
     1921 atttgtgacc tcagctttgg gaataaagga tcttttgaag gccaca
//