From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: S.pneumoniae (2039) ponA gene for penicillin-binding protein 1a
Date: 28 Dec 92 21:46:14 GMT
Distribution: bionet
Checksum: 32997 5

LOCUS       STRPONA5     2157 bp ds-DNA             BCT       02-DEC-1992
DEFINITION  S.pneumoniae (2039) ponA gene for penicillin-binding protein 1a
ACCESSION   X67870
KEYWORDS    penicillin-binding protein 1a; ponA gene.
SOURCE      Streptococcus pneumoniae DNA.
  ORGANISM  Streptococcus pneumoniae
            Prokaryotae; Firmicutes; Firmibacteria; Gram-positive cocci;
            Streptococcaceae.
REFERENCE   1  (bases 1 to 2157)
  AUTHORS   Martin,C., Sibold,C. and Hakenbeck,R.
  TITLE     Relatedness of penicillin-binding protein 1a genes from different
            clones of penicillin-resistant Streptococcus pneumoniae isolated in
            South Africa and Spain
  JOURNAL   EMBO J. 11, 3831-3836 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=2039; *source: cell_line=plant cultivar; *source:
            clone=pcMK1-pcMK16;
               From EMBL    entry SPPONA5;  dated 21-OCT-1992.
FEATURES             Location/Qualifiers
     CDS             1..>2157
                     /gene="ponA"
                     /product="penicillin-binding protein1a"
                     /codon_start=1
                     /translation="MNKQTILRIAKYVSICFLTLFITAVMLGGGIFLYYVSKAPALSE
                     SKLVATTSSKIFDSKNELIADLGSERRVNAQANEIPTDLVKAIVSIEDHRFFDHRCVD
                     TIRIIGAFLRNLQNNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLRELSLPQLALLAGMPQRPNQYDP
                     YSHPEAALDRRNLVLSEMKDQGYISAEQYEKAINTPITDGLQSLKSVNSYPAYMDNYL
                     KEVIDQVEQETGYNLLTTGMDVYTNVDQEAQKRLWDIYNSDQYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSTMKPITDYAPALEYGVYDSTAS
                     IVHDVPYNYPGTDTPLYNWDHVYFGNITIQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKQYGASSEKMAAAYAAFANGGIYHKPMYINKIVFS
                     DGSEKEFSDAGTRAMKETTAYMMTEMMKTVLADGIGRGAYLPWLPQAGKTGTSNYTDD
                     EIEKYIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPLVGDGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTDPNNNTQQSNTTPDQQNQNPQPAQP"
BASE COUNT      683 a    503 c    405 g    566 t
ORIGIN      
        1 atgaacaaac aaactatcct gcgaatagct aagtatgtga gtatctgctt cttaacttta
       61 tttatcacag cagttatgct gggaggaggc atatttctct attacgtcag caaagcccca
      121 gccctatctg agagcaaatt agtcgcaacc acgtctagta agattttcga tagtaaaaac
      181 gaactcattg ccgacttggg ctctgaacgc cgagtaaacg ctcaggccaa cgaaattcct
      241 actgatttgg tcaaggctat cgtatcgatt gaagaccatc gttttttcga tcatcgctgt
      301 gtcgatacca tccgaattat aggagctttt ttacgtaact tacaaaacaa ctccctccag
      361 ggaggatcaa cccttaccca acaattaatt aagttgacct atttctcaac ttccacttct
      421 gatcagacta tttcacgtaa agcccaggaa gcttggttgg ctattcaatt agagcaaaaa
      481 gcaaccaagc aagaaatcct gacctactac atcaacaaag tctacatgtc taacggtaac
      541 tatggaatgc aaacggctgc ccaaaactat tatggcaaag atttgcgaga actatcacta
      601 cctcaacttg ccctactagc aggaatgcca cagcgaccga atcaatacga tccctattct
      661 catccagaag ctgcccttga ccgtcgtaac ttggtacttt cagagatgaa ggatcaaggc
      721 tacatttctg ccgaacagta tgagaaggct atcaatactc ctattactga tggactccaa
      781 agtttgaaat cagtcaatag ctacccagca tatatggaca attatctcaa agaggttatc
      841 gaccaagtag aacaagaaac tggctataac cttctaacta ctgggatgga tgtttacaca
      901 aatgtagatc aagaggctca aaaacgtctg tgggatatct acaactccga tcaatacgtc
      961 tcttaccctg acgatgattt gcaagtcgca tctacggtcg tagatgtttc caatggtaaa
     1021 gtcatcgccc aacttggagc tcgtcaccaa gcaagtaacg tttcatttgg taccaaccaa
     1081 gccgttgaaa ccaatcgtga ctggggttct actatgaaac caatcactga ctatgctccc
     1141 gctttagaat atggagtcta tgactctact gcgtctattg tacatgatgt tccttataac
     1201 tatcctggca ctgatactcc gctctacaac tgggatcatg tctactttgg aaacattaca
     1261 atccagtatg ctcttcaaca atcacgaaat gtcacagccg ttgagacttt gaataaggtc
     1321 ggtctagata gagctaaaac ctttcttaat ggtcttggta tcgactatcc aagtatgcat
     1381 tacgcaaacg ccatttcaag taacacaact gaatccaaca aacagtacgg tgcaagtagt
     1441 gaaaaaatgg ctgctgctta tgccgccttt gctaatggtg gtatttacca caaaccaatg
     1501 tatatcaata aaatcgtctt cagtgatggt agtgaaaaag aattttctga tgctggtaca
     1561 cgagctatga aagaaactac tgcctatatg atgaccgaaa tgatgaaaac tgttttagct
     1621 gacggaatcg gacggggtgc ttacctacca tggcttccac aagcaggtaa gacaggtact
     1681 tctaactata ctgatgacga aattgaaaag tatatcaaga acactggcta cgtagctcca
     1741 gatgaaatgt ttgtaggtta tactcgtaag tattctatgg ctgtttggac aggatactca
     1801 aatcgtctga caccacttgt aggcgatggc cttacggtcg ctgctaaagt ttatcgctct
     1861 atgatgacct acctgtctga aggaagcaat ccagaggatt ggaatatacc agaggggctc
     1921 tacagaaatg gagaattcgt atttaaaaat ggtgctcgtt ctacgtggag ctcacctgct
     1981 ccacaacaac ccccatcaac tgaaagttca agctcatcat cagatagttc aacttcacag
     2041 tctagctcaa ccactccaag cacaaataat agtacgacta ccgatcctaa caataatacg
     2101 caacaatcaa atacaacccc tgatcaacaa aatcagaatc ctcaaccagc acaacca
//