From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human MHC class II lymphocyte antigen (HLA-DNA) gene, complete cds.
Date: 29 Sep 92 10:07:11 GMT
Distribution: bionet
Checksum: 49172     4

LOCUS       HUMPGDZ1     1106 bp ss-mRNA            PRI       29-SEP-1992
DEFINITION  Human MHC class II lymphocyte antigen (HLA-DNA) gene, complete cds.
ACCESSION   M31525 M35125
KEYWORDS    cell surface glycoprotein; class II gene; lymphocyte antigen;
            major histocompatibility complex.
SOURCE      Human B-cell cell line PGF, cDNA to mRNA, clone PGDZ1.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Young,J.A. and Trowsdale,J.
  TITLE     The HLA-DNA (DZA) gene is correctly expressed as a 1.1kb mature
            mRNA transcript
  JOURNAL   Immunogenetics 31, 386-388 (1990)
  STANDARD  full staff_review
COMMENT     Draft entry and computer-readable sequence for [1] kindly submitted
            by J.A.T.Young, 22-JAN-1990.
FEATURES             Location/Qualifiers
     mRNA            1..1106
                     /note="MHC HLA-DNA mRNA"
     sig_peptide     77..151
                     /note="MHC HLA-DNA signal peptide"
                     /codon_start=1
     CDS             77..829
                     /note="MHC HLA-DNA precursor"
                     /gene="HLA-DNA"
                     /codon_start=1
                     /translation="MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGA
                     SGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVER
                     SNRSRAINVPPRVTVLPKSRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQ
                     TSFYSQPDHLFRKFHYLPFVPSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMET
                     LVCALGLAIGLVGFLVGTVLIIMGTYVSSVPR"
     mat_peptide     152..826
                     /note="MHC HLA-DNA"
                     /codon_start=1
BASE COUNT      204 a    354 c    289 g    259 t
ORIGIN
        1 cttcttcttt acctccgcct tgttcctgtc ctcaccacac ggactgagac tgatttgatt
       61 aaagcaccag agtgtaatgg ccctcagagc agggctggtc ctggggttcc acaccctgat
      121 gaccctcctg agcccgcagg aggcaggggc caccaaggct gaccacatgg gctcctacgg
      181 acccgccttc taccagtctt acggcgcctc gggccagttc acccatgaat ttgatgagga
      241 acagctgttc tctgtggacc tgaagaaaag cgaggccgtg tggcgtctgc ctgagtttgg
      301 tgactttgcc cgctttgacc cgcagggcgg gctggccggc atcgccgcaa tcaaagccca
      361 tctggacatc ctggtggagc gctccaaccg cagcagagcc atcaacgtgc ctccacgggt
      421 gaccgtgctc cccaagtctc gggtggagct gggccagccc aacatcctca tctgcatcgt
      481 ggacaacatc ttcccccctg tgatcaatat cacctggctg cgcaacggcc aaactgtcac
      541 tgagggagtg gcccagacca gcttctattc ccagcctgac catttgttcc gcaagttcca
      601 ctacctgccc ttcgtgccct cagccgagga cgtctatgac tgccaggtgg agcactgggg
      661 cctggatgcg ccactcctca ggcattggga gctccaggtg cctattccac caccagatgc
      721 catggagacc ctggtctgtg ccctgggcct ggccatcggc ctggtgggct tcctcgtggg
      781 caccgtcctc atcatcatgg gcacatatgt gtccagtgtc cccaggtaat gatccttctg
      841 agagaaatga cttgtgggag acaccctgca gatcctcatg ggtttgtgac agcccctgcg
      901 tgctcagtgc cctttaagtg catcccgctg tgctgacttt gagtgggatc aacatctgtc
      961 ctacgggtcc cctctttttt ggccccagta ttcatggcag ggtttgttgg acacctacta
     1021 gcttcccttc ccattcaaca cacacacaca ttcttgctct acccaaagct ctggctggca
     1081 gcactaaatg ctttggtggt gtttgc
//