From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus gene for insulin-like growth factor binding protein-1
Date: 4 Sep 92 10:04:56 GMT
Distribution: bionet
Checksum: 22705     4

LOCUS       MUSILGF      1363 bp ds-DNA             ROD       04-SEP-1992
DEFINITION  M.musculus gene for insulin-like growth factor binding protein-1
ACCESSION   X67493
KEYWORDS    insulin-like growth factor binding protein-1.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Mohn,K.L., Waddle,J.R. and Taub,R.
  TITLE     Comparison of mouse and human IGFBP-1 genes reveals a potential
            insulin-responsive sequence and conservation of all intron/exon
            boundaries
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: strain=NIH Swiss; *source: stage=embryo; *source:
            cell_type=fibroblast; *source: cell_line=NIH 3T3; *source:
            clone_library=genomic, lambda FIX II; *source: clone=JW2.1;
            From EMBL    entry MMILGF;  dated 31-JUL-1992.
FEATURES             Location/Qualifiers
     misc_feature    500..508
                     /note="AP-2 consensus site"
     misc_feature    692..706
                     /note="insulin-responsive element"
     CAAT_signal     720..741
                     /note="Caat box with APF,HNF and NF-E1 consensussequences"
     TATA_signal     764..768
     misc_feature    792
                     /note="mRNA cap site"
     CDS             964..1336
                     /partial
                     /product="insulin-like growth factor bindingprotein-1"
                     /codon_start=1
                     /translation="MPEFLTVVSWPFLILLSFQIGVAAGAPQPWHCAPCTAERLGLCP
                     PVPASCPEISRPAGCGCCPTCALPMGAACGVATARCAQGLSCRALPGEPRPLHALTRG
                     QGASLPEPAAPATSTLFSSQHE"
                     /partial
     exon            964..1336
                     /number=1
BASE COUNT      285 a    398 c    340 g    340 t
ORIGIN
        1 tctagacctg gggacttaga agatattcac aggcaaggag gggggggggg tggtccatga
       61 tcagttttct ctgggaagtt ttggtgagat tccaaggtga gtcctatttc agattgccct
      121 taaacatttc tgaagttttc cttgtgatat aaaagaatga aaaaatgatg cagaaaaagc
      181 tgtcagactt gatcgttgat aagcatctca attacactag accattagac tgtcagagac
      241 agcttgggta tggcgatata gaccaagtgc ccggagtcct agcactttct ctctttgaag
      301 gcacaactgt tcttttggaa tttatagcca ggagccagga ggtgaactac ggatttcttc
      361 ctttgatggc tagaggcttc ctggggaggg agaaacaact gtgggcattg tcacggagag
      421 ccccactctt cccttccctt tgggcctgaa gccttcttgg tctaatctgt tctttcttta
      481 gtcgcttagg ttttctgtga gcctggccgg ctaggtcttt gatttcccct gaacaaaagc
      541 aagtgccctc ccccatctgg ctagcagctt gctgacagag ttggacttta gctcctgtcc
      601 cagtccatca ccacgggaca aacatagtag aaaacctgat ccctttaccc ccttccaccc
      661 acggtttgtg tagagctcac aagcaaaaca aacttatttt gaacactggg gtcctagcac
      721 gctgccctga caatcattaa cctgtgccgc acagccagcc cttcataagg ctctgggtac
      781 gaccagccag catggtccac tgcccgcgga gacacacacc cagcgagcat tgaacactgc
      841 acacggccgt ctgcccagag agctgtgacc accattgcca ctactatcta ctcagaaagt
      901 cgtgaccact gagcaactgc tgcctgtcca gagtctcatc cacagcctgc tgaaccagtt
      961 gcgatgcccg agttcctaac tgttgtttct tggccgttcc tgattctcct gtccttccag
     1021 attggcgtgg ccgctggagc cccccagcca tggcactgtg ctccctgcac tgctgagagg
     1081 ctggggctct gtccacccgt gcccgcttcg tgccccgaga tttctcggcc tgcaggctgt
     1141 ggctgctgcc cgacatgtgc cttgccgatg ggtgctgcct gcggtgtggc cactgctcgc
     1201 tgcgcccagg gactcagctg ccgtgcgttg ccaggagagc ctcgtcccct gcatgccctc
     1261 acccgtggtc agggagcctc tctaccagaa cctgctgcac ccgccacgag caccttgttc
     1321 agctcccagc atgaaggtac tgcagtccat ctctgcctct aga
//