From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Marek's disease virus, thymidine kinase gene, complete cds.
Date: 5 Jan 93 06:46:36 GMT
Distribution: bionet
Checksum: 11246 4

LOCUS       HSMTK        1437 bp ds-DNA             VRL       05-JAN-1993
DEFINITION  Marek's disease virus, thymidine kinase gene, complete cds.
ACCESSION   D13956 D00561
KEYWORDS    thymidine kinase.
SOURCE      Marek's disease virus, 3.5kbp BamHI fragment.
  ORGANISM  Gallid herpesvirus type 1
            Viridae; ds-DNA enveloped viruses; Herpesviridae;
            Gammaherpesviridae.
REFERENCE   1  (bases 1 to 1437)
  AUTHORS   Scott,S.D., Ross,N.L. and Binns,M.M.
  TITLE     Nucleotide and predicted amino acid sequence of the Marek's disease
            virus and turkey herpesvirus thymidine kinase genes; comparison
            with thymidine kinase genes of other herpesviruses
  JOURNAL   J. Gen. Virol. 70, 3055-3065 (1989)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CAAT_signal     50..57
     TATA_signal     162..167
     polyA_signal    1404..1409
     misc_signal     1428..1435
                     /note="termination element of mRNA"
     CDS             243..1301
                     /product="thymidine kinase"
                     /codon_start=1
                     /translation="MSEPQSWSVMASQMTSAQLIRVYLDGSMGIGKTSMLNEIPTHSL
                     MGVPVLKVFEPMKYWRYYFTDLVTTVNDTCDRRRRGEFSLFQSSMIVTALQSKFADPY
                     LVFHERLSSKCHRITGTRGNPSLILILDRHPISATVCFPIARHLTGDCSLEMLISMII
                     RLPQEPPGCNLVIVDLHDEKEHVSRLSSRNRTGEKTDLLMLRALNAVYSCLVDTIMYA
                     NHICPYSKDEWESEWLDLPWFDTSLATTFINEPRTDYRGSRVSLHHTLLAIFKRRELC
                     AEDGSLSTTHAWILWGLLMKLRNINVERFNITGLSTTKCVESFMDTMSERLVTHSSWN
                     DAFEIEADVLAYNKEMAM"
BASE COUNT      414 a    295 c    299 g    429 t
ORIGIN      51 bp upstream of HaeIII site.
        1 tacatctaat accatgacct tcccaaaaat tttggcaaag cttctccccg gccaatcata
       61 cacctgagat cctagacaca tcgcttctgc ataaagccgt ttgtaaaagc gatcgtgaca
      121 tcgaacacca gccgctaaac gtcgctttct aaggacattc gtatttacat gccgtttgaa
      181 atttcgagtg ctactaacct gtctgcgata tcttttgagt acgttcttct ctcccattga
      241 acatgtcgga gccacaatcg tggtcggtaa tggcatctca gatgacatct gcacagctca
      301 tacgtgtata cctcgatgga tcaatgggta taggtaaaac gtcaatgttg aatgagatac
      361 cgacgcactc tttaatggga gtacccgtac taaaggtttt cgaacctatg aaatactggc
      421 ggtattattt tactgatttg gtcacgaccg taaatgatac atgtgatcgt cgtcgcaggg
      481 gagagttttc tttatttcaa tctagcatga ttgtaacagc tttacaatca aagtttgcag
      541 atccctatct tgtatttcat gagcgcttat cgtcgaagtg tcatcgcata acaggaacac
      601 gtggcaatcc atcgcttata ttaattctag atcgacatcc catatccgct accgtatgtt
      661 ttcccattgc tcgacattta actggagatt gttccttgga gatgctaatt agtatgataa
      721 taaggttgcc ccaggaaccg ccaggatgca acttggtgat tgtcgatcta catgacgaaa
      781 aggagcatgt tagccgtcta tcttcacgga ataggaccgg cgagaaaaca gatctactaa
      841 tgctcagggc acttaatgca gtgtattcct gtttagtaga cactattatg tacgcaaatc
      901 atatttgtcc ctacagtaag gatgaatggg aatctgaatg gttggatcta ccatggtttg
      961 atacatcttt ggccacaacg tttataaacg aacctcgtac tgattatcgc ggtagtaggg
     1021 tgtcattaca ccatacgctt ttagcgatat ttaagcggcg agaattatgt gccgaagatg
     1081 gtagcttatc aacaacgcat gcatggatat tgtggggatt attaatgaaa ctgcggaaca
     1141 ttaacgtcga acgatttaat attactggcc tgtccacaac aaagtgtgta gaatcgttca
     1201 tggatactat gtcggagaga ttggtaacac atagtagctg gaatgatgcc ttcgagattg
     1261 aagctgatgt actagcctat aataaagaga tggctatgta aaactaccca ttcatatcgc
     1321 gcttctataa ttagcttgcc cacatcacaa tgatgcggca atattgactt atattaagat
     1381 agtaatttgg cgtccttaga tccaataaat atctatgatt tagtaagtgt gttcata
//