From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human dipeptidyl peptidase IV (CD26) mRNA, complete cds.
Date: 31 Jul 92 10:01:03 GMT
Distribution: bionet
Checksum: 58184     6

LOCUS       HUMCD26A     2924 bp ss-mRNA            PRI       31-JUL-1992
DEFINITION  Human dipeptidyl peptidase IV (CD26) mRNA, complete cds.
ACCESSION   M74777
KEYWORDS    T-cell activation antigen; cell surface antigen;
            dipeptidyl peptidase IV; transmembrane protein.
SOURCE      Homo sapiens (library: CDM7 expression library) peripheral blood
            cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2924)
  AUTHORS   Tanaka,T., Camerini,D., Seed,B., Torimoto,Y., Dang,N.H.,
            Kameoka,J., Dahlberg,H.N., Schlossman,S.F. and Morimoto,C.
  TITLE     Cloning and functional expression of the T cell activation antigen
            CD26
  JOURNAL   J. Immunol. 149, 481-486 (1992)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     CDS             11..2311
                     /EC_number="3.4.14.5"
                     /product="dipeptidyl peptidase IV"
                     /gene="CD26"
                     /codon_start=1
                     /translation="MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYT
                     LTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSI
                     NDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPV
                     GHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSP
                     NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL
                     SSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESS
                     GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKK
                     DCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELN
                     PERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQ
                     MPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATY
                     LASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI
                     AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDH
                     YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDH
                     GIASSTAHQHIYTHMSHFIKQCFSLP"
BASE COUNT      912 a    587 c    622 g    803 t
ORIGIN
        1 gacgccgacg atgaagacac cgtggaaggt tcttctggga ctgctgggtg ctgctgcgct
       61 tgtcaccatc atcaccgtgc ccgtggttct gctgaacaaa ggcacagatg atgctacagc
      121 tgacagtcgc aaaacttaca ctctaactga ttacttaaaa aatacttata gactgaagtt
      181 atactcctta agatggattt cagatcatga atatctctac aaacaagaaa ataatatctt
      241 ggtattcaat gctgaatatg gaaacagctc agttttcttg gagaacagta catttgatga
      301 gtttggacat tctatcaatg attattcaat atctcctgat gggcagttta ttctcttaga
      361 atacaactac gtgaagcaat ggaggcattc ctacacagct tcatatgaca tttatgattt
      421 aaataaaagg cagctgatta cagaagagag gattccaaac aacacacagt gggtcacatg
      481 gtcaccagtg ggtcataaat tggcatatgt ttggaacaat gacatttatg ttaaaattga
      541 accaaattta ccaagttaca gaatcacatg gacggggaaa gaagatataa tatataatgg
      601 aataactgac tgggtttatg aagaggaagt cttcagtgcc tactctgctc tgtggtggtc
      661 tccaaacggc acttttttag catatgccca atttaacgac acagaagtcc cacttattga
      721 atactccttc tactctgatg agtcactgca gtacccaaag actgtacggg ttccatatcc
      781 aaaggcagga gctgtgaatc caactgtaaa gttctttgtt gtaaatacag actctctcag
      841 ctcagtcacc aatgcaactt ccatacaaat cactgctcct gcttctatgt tgatagggga
      901 tcactacttg tgtgatgtga catgggcaac acaagaaaga atttctttgc agtggctcag
      961 gaggattcag aactattcgg tcatggatat ttgtgactat gatgaatcca gtggaagatg
     1021 gaactgctta gtggcacggc aacacattga aatgagtact actggctggg ttggaagatt
     1081 taggccttca gaacctcatt ttacccttga tggtaatagc ttctacaaga tcatcagcaa
     1141 tgaagaaggt tacagacaca tttgctattt ccaaatagat aaaaaagact gcacatttat
     1201 tacaaaaggc acctgggaag tcatcgggat agaagctcta accagtgatt atctatacta
     1261 cattagtaat gaatataaag gaatgccagg aggaaggaat ctttataaaa tccaacttag
     1321 tgactataca aaagtgacat gcctcagttg tgagctgaat ccggaaaggt gtcagtacta
     1381 ttctgtgtca ttcagtaaag aggcgaagta ttatcagctg agatgttccg gtcctggtct
     1441 gcccctctat actctacaca gcagcgtgaa tgataaaggg ctgagagtcc tggaagacaa
     1501 ttcagctttg gataaaatgc tgcagaatgt ccagatgccc tccaaaaaac tggacttcat
     1561 tattttgaat gaaacaaaat tttggtatca gatgatcttg cctcctcatt ttgataaatc
     1621 caagaaatat cctctactat tagatgtgta tgcaggccca tgtagtcaaa aagcagacac
     1681 tgtcttcaga ctgaactggg ccacttacct tgcaagcaca gaaaacatta tagtagctag
     1741 ctttgatggc agaggaagtg gttaccaagg agataagatc atgcatgcaa tcaacagaag
     1801 actgggaaca tttgaagttg aagatcaaat tgaagcagcc agacaatttt caaaaatggg
     1861 atttgtggac aacaaacgaa ttgcaatttg gggctggtca tatggagggt acgtaacctc
     1921 aatggtcctg ggatcaggaa gtggcgtgtt caagtgtgga atagccgtgg cgcctgtatc
     1981 ccggtgggag tactatgact cagtgtacac agaacgttac atgggtctcc caactccaga
     2041 agacaacctt gaccattaca gaaattcaac agtcatgagc agagctgaaa attttaaaca
     2101 agttgagtac ctccttattc atggaacagc agatgataac gttcactttc agcagtcagc
     2161 tcagatctcc aaagccctgg tcgatgttgg agtggatttc caggcaatgt ggtatactga
     2221 tgaagaccat ggaatagcta gcagcacagc acaccaacat atatataccc acatgagcca
     2281 cttcataaaa caatgtttct ctttacctta gcacctcaaa ataccatgcc atttaaagct
     2341 tattaaaact catttttgtt ttcattatct caaaactgca ctgtcaagat gatgatgatc
     2401 tttaaaatac acactcaaat caagaaactt aaggttacct ttgttcccaa atttcatacc
     2461 tatcatctta agtagggact tctgtcttca caacagatta ttaccttaca gaagtttgaa
     2521 ttatccggtc gggttttatt gtttaaaatc atttctgcat cagctgctga aacaacaaat
     2581 aggaattgtt tttatggagg ctttgcatag attccctgag caggatttta atctttttct
     2641 aactggactg gttcaaatgt tgttctcttc tttaaaggga tggcaagatg tgggcagtga
     2701 tgtcactagg gcagggacag gataagaggg attagggaga gaagatagca gggcatggct
     2761 gggaacccaa gtccaagcat accaacacga ccaggctact gtcagctccc ctcggagaaa
     2821 actgtgcagt ctgcgtgtga acagctcttc tcctttagag cacaatggat ctcgagggat
     2881 cttccatacc taccagttct gcgcctcgag gccgcgactc taga
//