From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus beta-adrenergic receptor kinase 2 (beta-ARK2)
Date: 3 Jan 93 22:08:34 GMT
Distribution: bionet
Checksum: 32636 6

LOCUS       RATBARK2     2464 bp ss-mRNA            ROD       21-DEC-1992
DEFINITION  Rattus norvegicus beta-adrenergic receptor kinase 2 (beta-ARK2)
            mRNA, complete cds.
ACCESSION   M87855
KEYWORDS    G protein-receptor kinase; beta adrenergic receptor kinase 2.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda-gt11)
            brain cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2464)
  AUTHORS   Arriza,J.L., Dawson,T.M., Simerly,R.B., Martin,L.J., Caron,M.G.,
            Snyder,S.H. and Lefkowitz,R.J.
  TITLE     The G protein-receptor kinases beta-ARK1 and beta-ARK2 are widely
            distributed at synapses in rat brain
  JOURNAL   J. Neurosci. 12, 4045-4055 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             4..2070
                     /gene="beta-ARK2"
                     /product="beta-adrenergic receptor kinase 2"
                     /codon_start=1
                     /translation="MADLEAVLADVSYLMAMEKSKATPAARASKKVVLPEPSIRSVMQ
                     RYLAERNEITFDKIFNQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRL
                     HRSRQMYDAYIMRELLSSTHQFSKQAVEHVQSHLSKKQVTPTLFQPYIEEICESLRGD
                     IFQKFMESEKFTRFCQWKNVELNIHLSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYA
                     MKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNG
                     GDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRIS
                     DLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFR
                     QHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCYGGGARELKEH
                     IFFKGIDWQYVYLRKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQDLYKN
                     FPLMISERWQQEVVETIYDAVNAETDKIEARKKAKNKQLCQEEDYAMGKDCIMHGYML
                     KLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQIMSVEETQIKDRKCILLRV
                     KGGKQFVLQCESDPEFAQWLKELTCTFNEAQRLLRRAPKFLNKPRAAILEFSKPPLCH
                     RNSSGL"
BASE COUNT      668 a    616 c    669 g    511 t
ORIGIN      
        1 gccatggcgg acctggaggc cgtgctggcc gacgtcagct acctgatggc catggagaag
       61 agcaaggcga cgccggccgc gcgcgccagc aagaaggtcg tcctgccgga gcccagtatc
      121 cggagtgtga tgcagaggta tctggcagaa agaaacgaaa taacctttga caagattttc
      181 aatcagaaaa tcggcttcct gctatttaaa gatttctgct tgaatgaaat cggtgaagcg
      241 gtgcctcagg tgaaatttta tgaagagata aaggaatacg agaaactgga caacgaagaa
      301 gaccggctgc accggagtcg gcagatgtac gacgcctaca tcatgaggga gcttctgtcc
      361 agcacacacc aattctcaaa gcaagctgta gaacatgtcc agagccatct ctccaagaag
      421 caggtgacgc ctaccctttt tcagccgtac atagaagaaa tctgcgaaag ccttcgaggc
      481 gacatcttcc aaaagtttat ggaaagcgaa aaattcacta gattctgtca gtggaagaat
      541 gtggaattga atattcatct gagcatgaac gacttcagtg tgcacaggat catcggccga
      601 ggagggtttg gggaagttta cggctgcagg aaagcagaca ccgggaaaat gtatgccatg
      661 aagtgcttag acaagaagag agtgaagatg aaacagggag agacactggc tttgaacgag
      721 aggatcatgt tgtctctcgt cagcactggg gactgtccct tcattgtctg catgacctat
      781 gccttccaca caccagacaa actctgcttc atcctggacc tgatgaacgg gggcgacatg
      841 cactaccacc tctcccagca cggggtgttc tctgagaagg agatgcgatt ttatgccagc
      901 gagatcatcc tgggcctcga gcacatgcac acctgctttg tagtctacag agacctgaag
      961 cctgcgaaca tcctcctgga tgaatatggg catgtgagga tatcggatct tggcctggcc
     1021 tgcgatttct ctaaaaagaa gcctcacgcc agtgtgggca cccatgggta catggctccc
     1081 gaggtgttgc agaaggggac atgctacgac agcagcgccg actggttctc cctgggctgc
     1141 atgctcttca agctcctgcg gggccacagc cctttcaggc agcataaaac caaagacaag
     1201 catgagatag accgcatgac cctgaccgtg aacgtgcagc ttccagatgc cttctcccct
     1261 gagctgaggt ccctcttgga gggtttgctc cagcgggatg tgagccagcg actgggctgc
     1321 tacggaggag gggcacgaga gttgaaggag cacatcttct tcaagggcat cgactggcag
     1381 tatgtgtact tacggaagta cccgccaccc ctaatccctc ctcggggaga ggtcaatgcc
     1441 gcagacgcct ttgatattgg ctcgtttgat gaagaagata ccaaaggcat taagctgttg
     1501 gactgcgacc aggacctcta taagaacttc ccgctgatga tttctgagcg ctggcagcag
     1561 gaagtagtgg agaccatcta cgacgccgtc aatgccgaaa ctgataaaat tgaggccagg
     1621 aagaaggcta aaaataaaca gctttgtcaa gaagaagatt atgccatggg gaaggactgc
     1681 atcatgcacg gatacatgct gaagctgggg aacccctttc tcacacagtg gcaaagacgt
     1741 tatttttacc tgtttcccaa cagactggag tggagaggag agggcgagtc tcggcaaaat
     1801 ctactgacca tggaacagat catgtctgtg gaggagaccc aaattaaaga cagaaaatgc
     1861 attttactca gggtaaaagg agggaagcag tttgttttgc aatgtgagag tgaccccgag
     1921 tttgcacagt ggctgaaaga gctgacgtgc accttcaacg aggcccagag actgctgcgc
     1981 cgcgccccca agttcctcaa caaaccacgt gccgccatcc tggagttctc caagccaccg
     2041 ctgtgtcaca gaaatagcag cggcctctga accacagagc agcagggcct gaaggaggcc
     2101 cccccccccc ggctcttcag ccccagcagt ggaatggagc cacggggaac cgtgtggggc
     2161 tgagacacag tggctctgag cactgggctg ctccaggctg aggaggccca caacaccggg
     2221 tggcccttca ggaactagga catccttggg gctggcctat ccacactcga aattactgaa
     2281 gaagcagagg catttttctg tgcaaccctc tcactttggt atccatggac ccagaacgta
     2341 aaatggttct tacctctcaa gcttttatgt ctgccacatt gttttgtcac aagataacac
     2401 actgaaaaag tattcttaag caaatagaaa caataggaaa aagattcggg agtcatccga
     2461 attc
//