From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for somatotropin receptor 5' upstream region
Date: 10 Apr 92 10:06:38 GMT
Distribution: bionet
Checksum: 15431     4

LOCUS       HUMSRECV3     154 bp ss-mRNA            PRI       10-APR-1992
DEFINITION  H.sapiens mRNA for somatotropin receptor 5' upstream region
ACCESSION   Z11851
KEYWORDS    growth hormone receptor; somatotropin receptor.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Leung,D.W., Spencer,S.A., Cachianes,G., Hammonds,R.G., Collins,C.,
            Henzel,W.J., Barnard,R., Waters,M.J. and Wood,W.I.
  TITLE     Growth hormone receptor and serum binding protein: purification,
            cloning and expression
  JOURNAL   Nature 330, 537-543 (1987)
  STANDARD  full staff_review
REFERENCE   2  (sites)
  AUTHORS   Godowski,P.J., Leung,D.W., Meacham,L.R., Galgani,J.P., Hellmiss,R.,
            Keret,R., Rotwein,P.S., Parks,J.S., Laron,Z. and Wood,W.I.
  TITLE     Characterization of the human growth hormone receptor gene and the
            demonstration of a partial gene deletion in two patients with
            Laron-type dwarfism
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 86, 8083-8087 (1989)
  STANDARD  full staff_review
REFERENCE   3  (bases 1 to 154)
  AUTHORS   Pekhletsky,R.I.
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_review
REFERENCE   4  (bases 1 to 154)
  AUTHORS   Pekhletsky,R.I. and Rubtsov,P.M.
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_review
COMMENT     *source: clone=V3;
            From EMBL    entry HSSRECV3;  dated 21-MAR-1992.
FEATURES             Location/Qualifiers
     misc_difference 1..20
                     /standard_name="growth hormone receptor"
                     /note="replace(1..20,
                     'tgtctgtaatcccaactaattgggaggcagacgcaggagaattgctaactagtt')"
                     /citation=[4]
                     /citation=[3]
                     /citation=[1]
                     /citation=[2]
                     /partial
     misc_difference 48..140
                     /standard_name="growth hormone receptor"
                     /note="replace(48..140,'')"
                     /citation=[4]
                     /citation=[3]
                     /citation=[1]
                     /citation=[2]
                     /partial
     exon            140..>154
                     /partial
                     /standard_name="growth hormone receptor"
                     /product="somatotropin receptor"
                     /citation=[3]
                     /citation=[1]
                     /citation=[2]
     CDS             152..>154
                     /partial
                     /standard_name="growth hormone receptor"
                     /product="somatotropin receptor"
                     /translation="M"
                     /citation=[3]
                     /citation=[1]
BASE COUNT       34 a     41 c     44 g     35 t
ORIGIN
        1 gcctgtctgt ttgtgccgcc aggagacctt ggaagggaca gagaaagagc tggggttttg
       61 ccatgttgcc caggctgatc tccaacacct gggatcaagc agtctgccca ccttggcctc
      121 ccaaagtgct gaaattacag gtcctacagg tatg
//