From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: pro-hormone convertase PC2 [swine, pituitary neurointermediate
Date: 3 Jan 93 22:20:43 GMT
Distribution: bionet
Checksum: 55021 6

LOCUS       S114156      2140 bp    mRNA            MAM       25-NOV-1992
DEFINITION  pro-hormone convertase PC2 [swine, pituitary neurointermediate
            lobes, mRNA, 2140 nt]
ACCESSION   S45536
KEYWORDS    .
SOURCE      swine pituitary neurointermediate lobes
  ORGANISM  Unclassified.
            Unclassified.
REFERENCE   1  (bases 1 to 2140)
  AUTHORS   Seidah,N.G., Fournier,H., Boileau,G., Benjannet,S., Rondeau,N. and
            Chretien,M.
  TITLE     The cDNA structure of the porcine pro-hormone convertase PC2 and
            the comparative processing by PC1 and PC2 of the N-terminal
            glycopeptide segment of porcine POMC.
  JOURNAL   FEBS Lett. 310, 235-239 (1992)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 114156] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 1.
FEATURES             Location/Qualifiers
     CDS             28..1944
                     /note="pPC2;  For the protein sequence (NCBI gibbsq
                     114158):  Method: conceptual translation supplied by
                     author.  This sequence comes from Fig. 1.  The authors
                     begin their numbering at -25.  Zero is not present in the
                     numbering."
                     /product="pro-hormone convertase PC2"
                     /codon_start=1
                     /translation="MKGGCVSQWKAAAGLLFCVTVFASAERPVFTNHFLVELHKGGEE
                     EARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQRLERDPRVKRALQQE
                     GFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKG
                     VTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSA
                     AANNNICGVGVAYSSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGK
                     TVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSA
                     INDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAG
                     VFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAG
                     AMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQ
                     AVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARG
                     TWTLELGFVGSAPQKGAVKEWTLMLHGSQSAPYIDQVVRDYQSKLAMSKKEELEEELD
                     EAVERSLKSILGKH"
BASE COUNT      513 a    607 c    609 g    411 t
ORIGIN      
        1 aacaccactt ttcactccca aagaaagatg aaaggtggct gtgtctccca gtggaaggcg
       61 gccgccgggc tcctcttctg tgtcacggtt tttgcgtctg ccgaaagacc ggtcttcaca
      121 aatcattttc ttgtggagtt gcataaaggg ggagaggaag aagctcgcca agttgcagca
      181 gaacacggct ttggagtccg aaagcttcct tttgctgaag gcctgtacca tttttatcac
      241 aatggcctgg caaaggccaa gagaagacgc agcctacacc ataagcagcg gctggagaga
      301 gaccccaggg taaagagagc tttgcaacag gaagggttcg atcggaaaaa gcgagggtat
      361 agagacatca atgaaatcga catcaacatg aatgaccctc tttttacgaa gcagtggtat
      421 ctgatcaata ctggacaagc tgatggtacc cctggccttg acttgaatgt ggcagaagcc
      481 tgggagctgg gatacactgg gaaaggtgtt accattggaa ttatggacga tggaatcgac
      541 tatctccacc cggacctggc ctcgaactac aatgcggaag cgagctacga ctttagcagc
      601 aacgacccct acccttaccc tcgctacaca gacgactggt ttaacagcca cgggacccga
      661 tgtgccgggg aggtttctgc cgcagccaac aacaatatct gcggggttgg agtggcctac
      721 agctccaagg ttgcaggtat ccggatgctg gaccagccct tcatgacgga catcatcgag
      781 gcctcttcca tcagccacat gcctcagcta attgacatct acagcgccag ctggggcccc
      841 accgacaacg ggaagacggt ggacgggccg cgggagctca cgcttcaggc gatggccgac
      901 ggtgtgaaca agggccgagg gggcaaaggc agcatctacg tgtgggcctc cggggacggt
      961 ggcagctacg acgactgcaa ctgtgacggc tatgcctcca gcatgtggac catctccatc
     1021 aactctgcca tcaacgacgg caggaccgcc ctgtacgacg agagctgctc ctccaccttg
     1081 gcctccacct tcagcaatgg gaggaagagg aaccccgagg ccggcgtggc aaccacagat
     1141 ttgtacggca actgcactct gaggcattct gggacatccg cggctgctcc tgaggcagct
     1201 ggagtgtttg cactggcttt agaggctaac ctgggtctga cctggagaga catgcagcat
     1261 ctgaccgtgc tcacttccaa acggaaccaa cttcatgatg aggtccatca gtggcggaga
     1321 aacggagtcg gcctagagtt taatcacctc tttggctatg gagtccttga cgcaggggcc
     1381 atggtgaaaa tggctaaaga ctggaaaacc gtgcctgaga gattccactg tgtgggaggc
     1441 tccgtacagg accctgaaaa aataccatcc actggcaagc tggtgctgac gctcaccacc
     1501 gatgcatgtg aggggaagga aaatttcgtc cgctacctgg agcacgtcca agctgtcatc
     1561 acggtcaatg cgacccggag aggagacctg aacattaaca tgacatcccc catgggcacc
     1621 aagtccatcc tgctgagccg gcgcccgagg gacgacgact ccaaggtggg cttcgacaag
     1681 tggcctttca tgaccaccca cacgtggggg gaggatgccc gaggcacctg gaccctggag
     1741 ctaggctttg tggggagcgc accccagaag ggggctgtga aggagtggac gctgatgctg
     1801 cacggcagcc agagcgcccc ttacatcgac caggtggtga gggattacca gtccaagctg
     1861 gccatgtcca agaaggagga gctggaggaa gagctggacg aagcagtgga gagaagcctg
     1921 aagagcatcc tgggcaagca ctagcgccac ctcctggccg ccgccgccgc cctgcccgac
     1981 tctgcctctg tcctcgctcc acatcccacc catcgcctcg caatcactgt cccccgaccc
     2041 acgattcctg atccgccttc gctcactgtc ggtgattatt ttcattacca tgaaagcaag
     2101 cttttttatt ctgtgcccca aatacagtgt tcccacccac
//