From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human phospholipase A2 mRNA, complete cds.
Date: 21 Jul 92 10:05:39 GMT
Distribution: bionet
Checksum: 20082     6

LOCUS       HUMPHPLA2    2834 bp ss-mRNA            PRI       21-JUL-1992
DEFINITION  Human phospholipase A2 mRNA, complete cds.
ACCESSION   M86400
KEYWORDS    phospholipase A2.
SOURCE      Homo sapiens (library: Lambda gt11) placenta cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2834)
  AUTHORS   Zupan,L.A., Steffens,D.L., Berry,C.A., Landt,M.L. and Gross,R.W.
  TITLE     Cloning and expression of a human 14-3-3 protein mediating
            phospholysis: Identification of an arachidonoyl-enzyme intermediate
            during catalysis
  JOURNAL   J. Biol. Chem. 267, 8707-8710 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     misc_signal     82..88
                     /standard_name="Kozak initiation sequence"
     CDS             85..822
                     /function="transacylation"
                     /EC_number="3.1.1.4"
                     /product="phospholipase A2"
                     /codon_start=1
                     /translation="MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLL
                     SVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLE
                     KFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEM
                     QPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIM
                     QLLRDNLTLWTSDTQGDEAEAGEGGEN"
BASE COUNT      831 a    541 c    550 g    912 t
ORIGIN
        1 gcccactccc accgccagct ggaaccctgg ggactacgac gtccctcaaa ccttgcttct
       61 aggagataaa aagaacatcc agtcatggat aaaaatgagc tggttcagaa ggccaaactg
      121 gccgagcagg ctgagcgata tgatgacatg gcagcctgca tgaagtctgt aactgagcaa
      181 ggagctgaat tatccaatga ggagaggaat cttctctcag ttgcttataa aaatgttgta
      241 ggagcccgta ggtcatcttg gagggtcgtc tcaagtattg aacaaaagac ggaaggtgct
      301 gagaaaaaac agcagatggc tcgagaatac agagagaaaa ttgagacgga gctaagagat
      361 atctgcaatg atgtactgtc tcttttggaa aagttcttga tccccaatgc ttcacaagca
      421 gagagcaaag tcttctattt gaaaatgaaa ggagattact accgttactt ggctgaggtt
      481 gccgctggtg atgacaagaa agggattgtc gatcagtcac aacaagcata ccaagaagct
      541 tttgaaatca gcaaaaagga aatgcaacca acacatccta tcagactggg tctggccctt
      601 aacttctctg tgttctatta tgagattctg aactccccag agaaagcctg ctctcttgca
      661 aagacagctt ttgatgaagc cattgctgaa cttgatacat taagtgaaga gtcatacaaa
      721 gacagcacgc taataatgca attactgaga gacaacttga cattgtggac atcggatacc
      781 caaggagacg aagctgaagc aggagaagga ggggaaaatt aaccggcctt ccaacttttg
      841 tctgcctcat tctaaaattt acacagtaga ccatttgtca tccatgctgt cccacaaata
      901 gttttttgtt tacgatttat gacaggttta tgttacttct atttgaattt ctatatttcc
      961 catgtggttt ttatgtttaa tattagggga gtagagccag ttaacattta gggagttatc
     1021 tgttttcatc ttgaggtggc caatatgggg atgtggaatt tttatacaag ttataagtgt
     1081 ttggcatagt acttttggta cattgtggct tcaaaagggc cagtgtaaaa ctgcttccat
     1141 gtctaagcaa agaaaactgc ctacatactg gtttgtcctg gcggggaata aaagggatca
     1201 ttggttccag tcacaggtgt agtaattgtg ggtactttaa ggtttggagc acttacaagg
     1261 ctgtggtaga atcatacccc atggatacca catattaaac catgtatatc tgtggaatac
     1321 tcaatgtgta cacctttgac tacagctgca gaagtgttcc tttagacaaa gttgtgaccc
     1381 attttactct ggataagggc agaaacggtt cacattccat tatttgtaaa gttacctgct
     1441 gttagctttc attatttttg ctacactcat tttatttgta tttaaatgtt ttaggcaacc
     1501 taagaacaaa tgtaaaagta aagatgcagg aaaaatgaat tgcttggtat tcattacttc
     1561 atgtatatca agcacagcag taaaacaaaa acccatgtat ttaacttttt tttaggattt
     1621 ttgcttttgt gatttttttt tttttttttt gatacttgcc taacatgcat gtgctgtaaa
     1681 aatagttaac agggaaataa cttgagatga tggctagctt tgtttaatgt cttatgaaat
     1741 tttcatgaac aatccaagca taattgttaa gaacacgtgt attaaattca tgtaagtgga
     1801 ataaaagttt tatgaatgga cttttcaact actttctcta cagcttttca tgtaaattag
     1861 tcttggttct gaaacttctc taaaggaaat tgtacattct ttgaaattta ttccttattc
     1921 cctcttggca gctaatgggc tcttaccaag tttaaacaca aaatttatca taacaaaaat
     1981 actactaata taactactgt ttccatgtcc catgatcccc tctcttcctc cccaccctga
     2041 aaaaaatgag ttcctatttt ttctgggaga gggggggatt gattagaaaa aaatgtagtg
     2101 tgttccattt aaaattttgg catatggcat tttctaactt aggaagccac aatgttcttg
     2161 gcccatcatg acattgggta gcattaactg taagttttgt gcttccaaat cactttttgg
     2221 tttttaagaa tttcttgata ctcttatagc ctgccttcaa ttttgatcct ttattctttc
     2281 tatttgtcag gtgcacaaga ttaccttcct gttttagcct tctgtcttgt caccaaccat
     2341 tcttacttgg tggccatgta cttggaaaaa ggccgcatga tctttctggc tccactcagt
     2401 gtctaaggca ccctgcttcc tttgcttgca tcccacagac tatttccctc atcctattta
     2461 ctgcagcaaa tctctcctta gttgatgaga ctgtgtttat ctccctttaa aaccctacct
     2521 atcctgaatg gtctgtcatt gtctgccttt aaaatccttc ctctttcttc ctcctctatt
     2581 ctctaaataa tgatggggct aagttatacc caaagctcac tttacaaaat atttcctcag
     2641 tactttgcag aaaacaccaa acaaaaatgc cattttaaaa aaggtgtatt ttttctttta
     2701 gaatgtaagc tcctcaagag cagggacaat gttttctgta tgttctattg tgcctagtac
     2761 actgtaaatg ctcaataaat attgatgatg ggaggcagtg agtcttgatg ataagggtga
     2821 gaaactgaaa tccc
//