From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Schistosoma japonicum (clone C32) 22.6kd tegumental associated
Date: 3 Jan 93 22:26:01 GMT
Distribution: bionet
Checksum: 51703 4

LOCUS       SCMTEGUMEN    777 bp ss-mRNA            INV       24-DEC-1992
DEFINITION  Schistosoma japonicum (clone C32) 22.6kd tegumental associated
            antigen mRNA, complete cds.
ACCESSION   L08198
KEYWORDS    22.6kd tegumental associated antigen.
SOURCE      Schistosoma japonicum (strain Chinese) (library: lambda-ZAPII)
            adult cDNA to mRNA.
  ORGANISM  Schistosoma japonicum
            Eukaryota; Animalia; Eumetazoa; Platyhelminthes; Trematoda;
            Digenea; Strigeidida; Strigeata; Schistosomatoidea;
            Schistosomatidae.
REFERENCE   1  (sites)
  AUTHORS   Jeffs,S.A., Hagan,P., Allen,R., Correa-Oliveira,R., Smithers,S.R.
            and Simpson,A.J.
  TITLE     Molecular cloning and characterisation of the Mr22k adult
            Schistosoma mansoni antigen recognised by anitbodies from mice
            protectively vaccinated with isolated tegumental surface membranes
  JOURNAL   Mol. Biochem. Parasitol. 46, 159-168 (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 777)
  AUTHORS   Waine,G.J., Becker,M., Kalinna,B., Yang,W. and Mcmanus,D.P.
  TITLE     Cloning and full cDNA sequence of a 22.6kd antigen of Schistosoma
            japonicum: a potential vaccine candidate against schistosomiasis
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             10..585
                     /citation=[1]
                     /note="sequence exhibits 71% homology to 22.6kd tegumental
                     associated antigen of Schistosoma mansoni (assession
                     number M37003) but encodes a proteinone amino acid longer;
                     putative"
                     /product="22.6kd tegumental associated antigen"
                     /codon_start=1
                     /translation="MATTEYRLSLMEQFIRAFIEIDKDNNELIDKQELTKYCQQNQMD
                     MKQIDPWIARFDTDKDGKVSLEEFCRGFGLKVWEVRREKEELKRDKEGKVSTLPLDIQ
                     IIAATMSKAKQYNICCKFKELLDKTSRTGDEVRALANDLKAFLDSEYGRVWQVIILTG
                     SYWMNFSHEPFLSMQFKYSNYVCLLWRTPSS"
BASE COUNT      289 a    102 c    141 g    245 t
ORIGIN      
        1 cttgttatta tggcaactac tgagtacaga ttaagtttaa tggaacaatt tattagagca
       61 ttcatagaaa tagataaaga taataatgaa ttgattgata aacaagaact aacgaaatat
      121 tgtcaacaga atcaaatgga tatgaaacaa atagatccat ggattgcaag gtttgatact
      181 gataaagatg gtaaagtcag tttagaggag ttttgtcgtg gattcggtct aaaggtttgg
      241 gaagtccgtc gtgaaaagga agaattaaag agagacaagg aaggcaaagt atccacactt
      301 ccactggata ttcaaattat cgcggcaacc atgtcaaaag ctaagcaata taacatatgt
      361 tgtaaattta aagaacttct tgataaaact agtcgaactg gtgatgaagt aagagcgttg
      421 gcaaatgact taaaagcatt tttggattct gaatatggcc gtgtatggca agtgattata
      481 ctaactggtt catattggat gaatttttca catgaaccat ttttatcaat gcagtttaag
      541 tacagtaatt atgtttgtct attgtggcga acaccgtctt cgtaaagttt aatgaatagt
      601 acaaatgaat atacattcat acacaataaa gcgacagtat gctaatctac tattcataac
      661 tgcaataata atgacaattt ttacataact ttgaatttgt tcaatgatta attactagtg
      721 ctttaactaa ctcaaattct aatcattttg ttatgaatga caaaacagta cattatt
//