From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus mRNA for Apolipoprotein A-I
Date: 24 Jul 92 10:08:18 GMT
Distribution: bionet
Checksum: 36895     3

LOCUS       MUSAPOAI      924 bp ss-RNA             ROD       24-JUL-1992
DEFINITION  M.musculus mRNA for Apolipoprotein A-I
ACCESSION   X64262
KEYWORDS    apolipoprotein A-I.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Stoffel,W., Mueller,R., Binczek,E. and Hofmann,K.
  TITLE     Mouse apolipoprotein AI: cDNA-derived primary structure, gene
            organisation and complete nucleotide sequence
  JOURNAL   Biol. Chem. Hoppe-Seyler 373, 187-193 (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=liver; *source: clone_library=cDNA;
            See also X64263
            From EMBL    entry MMAPOAI;  dated 21-MAY-1992.
FEATURES             Location/Qualifiers
     sig_peptide     49..120
                     /note="pre-prosequence"
                     /product="Apoprotein A-I"
     CDS             49..843
                     /function="acts as a cofactor for the lecithincholesterol
                     acyltransferase"
                     /product="precursor Apoprotein A-I"
                     /gene="apoAI"
                     /codon_start=1
                     /translation="MKAVVLAVALVFLTGSQAWHVWQQDEPQSQWDKVKDFANVYVDA
                     VKDSGRDYVSQFESSSLGQQLNLNLLENWDTLGSTVSQLQERLGPLTRDFWDNLEKET
                     DWVRQEMNKDLEEVKQKVQPYLDEFQKKWKEDVELYRQKVAPLGAELQESARQKLQEL
                     QGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMRESLAQRLAELKSNPTLNEYHTRAK
                     THLKTLGEKARPALEDLRHSLMPMLETLKTKAQSVIDKASETLTAQ"
     mat_peptide     121..840
                     /product="Apoprotein A-I"
                     /gene="apoAI"
     polyA_signal    886..891
     polyA_site      905
BASE COUNT      251 a    254 c    265 g    154 t
ORIGIN
        1 accccagact gtcggagagc tccggggagg tcacccacac ccttcaggat gaaagctgtg
       61 gtgctggccg tggctctggt cttcctgaca gggagccagg cttggcacgt atggcagcaa
      121 gatgaacccc agtcccaatg ggacaaagtg aaggatttcg ctaatgtgta tgtggatgcg
      181 gtcaaagaca gcggcagaga ctatgtgtcc cagtttgaat cctcctcctt gggccaacag
      241 ctgaacctga atctcctgga aaactgggac actctgggtt caaccgttag tcagctgcag
      301 gaacggctgg gcccattgac tcgggacttc tgggataacc tggagaaaga aacagattgg
      361 gtgagacagg agatgaacaa ggacctagag gaagtgaaac agaaggtgca gccctacctg
      421 gacgaattcc agaagaaatg gaaagaggat gtggagctct accgccagaa ggtggcgcct
      481 ctgggcgccg agctgcagga gagcgcgcgc cagaagctgc aggagctgca agggagactg
      541 tcccctgtgg ctgaggaatt tcgcgaccgc atgcgcacac acgtagactc tctgcgcaca
      601 cagctagcgc cccacagcga acagatgcgc gagagcctgg cccagcgcct ggctgagctc
      661 aagagcaacc ctaccttgaa cgagtaccac accagggcca aaacccacct gaagacactt
      721 ggcgagaaag ccagacctgc gctggaggac ctgcgccata gtctgatgcc catgctggag
      781 acgcttaaga ccaaagccca gagtgtgatc gacaaggcca gcgagactct gactgcccag
      841 tgaggtgccc gcttccactc cccacccccg cattggcttt cttacaataa acctttccaa
      901 aatggaaaaa aaaaaaaaaa aaaa
//