From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus DNA for VSAG1 viral superantigen
Date: 9 Apr 92 10:04:20 GMT
Distribution: bionet
Checksum: 57083     5

LOCUS       MUSVSAG1      977 bp ds-DNA             ROD       09-APR-1992
DEFINITION  M.musculus DNA for VSAG1 viral superantigen
ACCESSION   X63024
KEYWORDS    MHC class II molecule binding; T-cell activation; T-cell receptor;
            V beta 3 binding; VSAG1 gene; deletion;
            mammary tumour virus 1 superantigen; viral superantigen.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 977)
  AUTHORS   Crouse,C. and Pauley,R.J.
  TITLE     Molecular cloning and sequencing of the MTV-1 LTR: Evidence for a
            LTR sequence alteration
  JOURNAL   Virus Res. 12, 123-138 (1989)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 977)
  AUTHORS   Pullen,A.M.
  JOURNAL   Unpublished (1991)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 977)
  AUTHORS   Pullen,A.M., Choi,Y., Kushnir,E., Kappler,J. and Marrack,P.
  TITLE     The open reading frames in the 3' long terminal repeats of several
            mouse mammary tumour virus integrants encode Vbeta3-specific
            superantigens
  JOURNAL   J. Exp. Med. 175, 41-47 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=ssp.Domesticus; strain DBA/2; *source: stage=adult;
            *source: tissue=liver; *source: chromosome=7; *source: is_germline=
            Y;
            Related sequence: Crouse,C.A. and Pauley,R.J., Virus res. 12:
            123-138 (1989)
            From EMBL    entry MMVSAG1;  dated 11-FEB-1992.
FEATURES             Location/Qualifiers
     CDS             1..948
                     /product="mammary tumour virus 1, superantigen"
                     /gene="VSAG1 (viral superantigen)"
                     /translation="MPRLQQKWLNSRECPTLRREAAKGLFPTKDDPSACTRMSPSDKD
                     ILILCCKLGIALLCLGLLGEVAVRARRALTLDSFNNSSVQDYNLNDSENSTFLLGQGP
                     QPTSSYKPHRLCPSEIEIRMLAKNYIFTNETNPIGRLLIMMLRNESLSFSTIFTQIQR
                     LEMGIENRKRRSTSVEEQVQGLRASGLEVKRGKRSALDKIGDRWWQPGTYRGPYIYRP
                     TDAPLPYTGRYDLNFDRWVTVNGYKVLYRSLPFRERLARARPPWCVLSQEEKDDMKQQ
                     VHDYIYLGTGMIHWKVFYNSREEAKRHIIEHIKALPLAF"
     CDS             112..948
                     /product="mammary tumour virus 1, superantigen"
                     /gene="VSAG1 (viral superantigen)"
                     /translation="MSPSDKDILILCCKLGIALLCLGLLGEVAVRARRALTLDSFNNS
                     SVQDYNLNDSENSTFLLGQGPQPTSSYKPHRLCPSEIEIRMLAKNYIFTNETNPIGRL
                     LIMMLRNESLSFSTIFTQIQRLEMGIENRKRRSTSVEEQVQGLRASGLEVKRGKRSAL
                     DKIGDRWWQPGTYRGPYIYRPTDAPLPYTGRYDLNFDRWVTVNGYKVLYRSLPFRERL
                     ARARPPWCVLSQEEKDDMKQQVHDYIYLGTGMIHWKVFYNSREEAKRHIIEHIKALPL
                     AF"
     conflict        934..936
                     /note="replace(934..936,'cc')"
                     /citation=[1]
                     /partial
BASE COUNT      305 a    205 c    223 g    244 t
ORIGIN
        1 atgccgcgcc tgcagcagaa atggttgaac tcccgagagt gtcctacact taggagagaa
       61 gcagccaagg ggttgtttcc caccaaggac gacccgtctg cgtgcacgcg gatgagccca
      121 tcagacaaag acatactcat tctctgctgc aaacttggca tagctctgct ttgcctgggg
      181 ctattggggg aagttgcggt tcgtgctcgc agggctctca cccttgactc ttttaataac
      241 tcttctgtgc aagattacaa tctaaacgat tcggagaact cgaccttcct cctggggcaa
      301 ggaccacagc caacttcctc ttacaagcca caccgacttt gtccttcaga aatagaaata
      361 agaatgcttg ctaaaaacta tatttttacc aatgagacca atccaatagg tcgattatta
      421 atcatgatgt taagaaatga atctttgtct tttagcacta tatttactca aattcaaagg
      481 ttagaaatgg gaatagaaaa tagaaagaga cgctcaacct cagttgaaga acaggtgcaa
      541 ggactaaggg cctcaggcct agaagtaaaa aggggaaaga ggagtgcgct tgacaaaata
      601 ggagacaggt ggtggcaacc agggacttat aggggacctt acatttacag accaacagac
      661 gccccgttac catatacagg aagatatgat ttaaattttg ataggtgggt cacagtcaac
      721 ggctataaag tgttatacag atccctcccc tttcgtgaaa ggctcgccag agctagacct
      781 ccttggtgtg tgttgtctca agaagaaaaa gacgacatga aacaacaggt acatgattat
      841 atttatctag gaacaggaat gatacattgg aaagtatttt ataacagtag agaggaggcc
      901 aaaagacata taatagaaca tattaaggct ttgcccttag ctttctaaag tttgcttgcg
      961 gttcccaagg tttaagt
//