From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human AMP deaminase (AMPD3) mRNA, complete cds.
Date: 3 Jan 93 22:06:05 GMT
Distribution: bionet
Checksum: 56736 7

LOCUS       HUMAMPD3B    3680 bp ss-mRNA            PRI       21-DEC-1992
DEFINITION  Human AMP deaminase (AMPD3) mRNA, complete cds.
ACCESSION   M84721
KEYWORDS    AMP deaminase.
SOURCE      Homo sapiens cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Mahnke-Zizelman,D.K. and Sabina,R.L.
  TITLE     Cloning of human AMP deaminase isoform E cDNA: Evidence for a third
            AMPD gene exhibiting alternatively spliced 5'-exons
  JOURNAL   J. Biol. Chem. 267, 20866-20877 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..134
                     /gene="AMPD3"
     3'UTR           2439..3680
                     /gene="AMPD3"
     polyA_signal    3659..3664
                     /gene="AMPD3"
     CDS             135..2438
                     /EC_number="3.5.4.6"
                     /gene="AMPD3"
                     /product="AMP deaminase"
                     /codon_start=1
                     /translation="MPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVP
                     EDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAA
                     SPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALM
                     IREKYARLAYHRFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNL
                     DYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHR
                     RLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIK
                     HTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSK
                     YNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEW
                     PNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQ
                     DHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANI
                     MVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYL
                     AQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIA
                     AQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMA
                     FRYETLCNELSFLSDAMKSEEITALTN"
BASE COUNT      922 a    950 c    896 g    912 t
ORIGIN      
        1 tcaaccctgc ttggttttag aggattgctc ccgtgggtca cttgaggcag gctccacctt
       61 ccccaggagg agtggcagag tccagccagc gctcggagct ggaggcccac gtgggagcag
      121 tgagcggctc tgagatgccg cggcagtttc ccaagctgaa catctctgaa gtggatgagc
      181 aagtccggct cctggcggag aaggtgtttg ctaaagtgct ccgagaagag gacagcaaag
      241 atgccctgtc cctgttcact gtcccagagg actgccccat cgggcaaaag gaagccaagg
      301 agagggagct gcagaaggag ctggcagagc agaagtctgt ggagaccgca aaaagaaaga
      361 aaagtttcaa gatgattcgg tcccagtccc tgtctctgca aatgccgcca cagcaagatt
      421 ggaagggccc cccggcagcc agtccggcca tgtctcccac aacccctgtg gtcactggag
      481 ccacttccct gcccacgcca gcaccctatg ccatgcctga gttccagcgg gtcaccatca
      541 gcggagatta ctgtgccggg atcactttgg aggactatga gcaggcagcc aagagtctgg
      601 ccaaggccct aatgatccgg gagaagtatg cgcggctcgc ctaccaccgc ttcccgcgga
      661 tcacatccca gtacctgggt catccgcggg cggatactgc acctccggaa gagggccttc
      721 cagacttcca ccctcctcca ctgccccagg aagaccccta ctgcctggat gatgcacccc
      781 ccaacctgga ttacttggtc cacatgcagg ggggcatcct ctttgtgtat gataacaaga
      841 agatgctgga gcaccaggag ccgcacagcc taccctaccc cgacctggag acctacacgg
      901 tggacatgag ccacatcctg gctctcatca ccgatggccc cacgaaaacc tattgtcacc
      961 ggcgactgaa ctttctggaa tccaagttca gccttcatga gatgttaaac gaaatgtccg
     1021 agttcaaaga gttgaagagt aacccccacc gggacttcta taacgtgaga aaggtggaca
     1081 cacacatcca tgcggccgcc tgcatgaacc aaaagcatct gctgcgcttc atcaagcaca
     1141 cataccagac ggagcctgac aggactgtgg cagagaagcg gggccggaag atcaccctgc
     1201 ggcaggtgtt tgacggcctg cacatggacc cctacgacct cactgtggac tcactggatg
     1261 tccacgcggg ccggcagaca ttccaccgct ttgacaagtt caactccaaa tacaaccctg
     1321 tgggggccag tgagctgcgt gacctgtatt tgaaaactga aaactatctg ggaggagagt
     1381 actttgctcg gatggtcaag gaggttgccc gggagctgga ggagagcaag taccagtact
     1441 cagagccacg gctctccatc tacggccgca gtcctgagga gtggcccaac ctggcctact
     1501 ggttcatcca gcacaaggtc tactctccca acatgcgctg gatcatccag gtgccccgga
     1561 tttatgacat atttaggtca aagaagctgc tgccaaactt tgggaagatg ctggagaaca
     1621 tcttcctgcc ccttttcaag gccactatca acccccaaga tcatcgagag cttcacctct
     1681 tccttaaata tgtgacgggg tttgacagcg tggatgatga gtccaagcac agcgaccaca
     1741 tgttttccga caagagccca aacccggacg tctggaccag tgagcagaac ccaccctaca
     1801 gctactacct gtactacatg tatgccaaca tcatggtgct caacaacctc cgcagggagc
     1861 gcggcctgag cacgttcctg ttccggccgc actgtgggga agccggctcc atcacccacc
     1921 tggtgtctgc cttcctcact gctgacaaca tttcccacgg gctgctcctc aagaagagtc
     1981 cggtattgca gtatctctac taccttgctc agatccccat tgccatgtct cctcttagca
     2041 acaacagttt gttcctcgaa tattccaaga accctctgag ggaattccta cacaagggac
     2101 tgcatgtttc tctttccacc gatgacccca tgcagttcca ctacacgaag gaagcactta
     2161 tggaagaata tgccattgca gctcaagtgt ggaagctgag cacctgcgac ctgtgtgaga
     2221 tcgccaggaa cagcgtgctg cagagcggcc tctcgcatca ggaaaagcaa aagtttctgg
     2281 gacaaaatta ttataaagaa ggacctgaag gaaatgatat tcgaaagaca aatgtggctc
     2341 agatccggat ggcattccga tatgagacct tatgcaatga gctcagcttc ctgtctgatg
     2401 ctatgaaatc agaagagatc accgccttga ccaactaggt ccagcatttg acatgcattt
     2461 taactttttg gttcaatttc aagtctgctg tggctaatag tggtcaagat tccgaactag
     2521 gactttcctc tgtgaagagg atgcctctga agaaatttta aactggtgat tttggttgca
     2581 ctgctcactt taagagttaa catgctcact tgttagtatt tctgagtaac aagatggtga
     2641 cttctccttg gggatctggg agctgagcac ttgtctatac ttgttcctaa ttttccaagt
     2701 atttctcttg aaactgccag tgcctgaact gttggggcca ggattttccc tggtcagatg
     2761 ccaagtaaca tgtggttttc tgccatactt ttctccattg gcccaggtag gctaattggt
     2821 agttgttcat ttcagcctct ggatggctgg ctggccttaa acacaatcaa tttcaaagct
     2881 ccattttcat aaaggggcta ctttgaagga gttaagatgg aagacttcct tcttgacaaa
     2941 ttgtgttttt agtgaatttc ttaaaccgtt ttatttagcc ctccttccct ctttctagtt
     3001 ggaagccaaa tgtactcatg aaaacagcca ctcctattct gagtcttggt ttcttcacct
     3061 agaaagtgag ggtttggact agatgagtgg ctttcagggt gttctgtgaa tctcctcatg
     3121 aatactttag ggtgggggag ggaagggagt gagtgatgct caggggctgt caaagtgact
     3181 gcgttcatca gttttacact ggggctgcta cataatattt tcatttgaac gaagaacttc
     3241 aaaaagcaca ggactagatg atctctgttc cttttggctc taatatgcta caactgtagg
     3301 ccaattatca ctttaccaat taagagttag gccagataag tgaaatttaa cttaagggca
     3361 cacagctaat aagtaatagg cctaaactgg atttccttat tccaaatcct gtcttttccc
     3421 cactattcca ttagacccca caaatgttag ttgtgtgtgt gtgtgtgtgt gtttttaatc
     3481 actgtaaccg ggtgcatttt tttaaggcaa aatttctccc ttatctactg tgatgacttc
     3541 agaagataca atggtcccag gggccaagta gaaagcattt ttaaagatta atctgaatta
     3601 agctttatca gtgtactctt tatctgtgtt actagtgcct ggtatgtagt aggtgctcaa
     3661 taaatgcata ttgaataact
//