From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human cathepsin L (CTSL) gene, exon 1, intron 1, and exon 2
Date: 21 Dec 92 20:44:03 GMT
Distribution: bionet
Checksum: 03987 4

LOCUS       HUMCATHLA    1484 bp ds-DNA             PRI       17-NOV-1992
DEFINITION  Human cathepsin L (CTSL) gene, exon 1, intron 1, and exon 2
            including 5' end of cds.
ACCESSION   L06426
KEYWORDS    alternative splicing; cathepsin L.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1484)
  AUTHORS   Chauhan,S.S., Popescu,N.P., Ray,D., Fleischmann,R., Gottesman,M.M.
            and Troen,B.R.
  TITLE     Cloning, genomic organization, and chromosomal localization of
            human cathepsin L
  JOURNAL   J. Biol. Chem. (1993) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            join(1..278,1465..>1484)
                     /standard_name="hCATL-A"
                     /note="alternate"
                     /gene="CTSL"
                     /partial
     exon            1..278
                     /number=1A
                     /gene="CTSL"
     intron          279..1464
                     /number=1
                     /gene="CTSL"
     exon            1281..>1484
                     /number=1B
                     /note="alternate"
                     /gene="CTSL"
                     /note="putative"
     mRNA            1281..>1464
                     /standard_name="hCATL-B"
                     /note="alternate"
                     /gene="CTSL"
                     /note="putative"
     exon            1465..>1484
                     /number=2A
                     /gene="CTSL"
     CDS             1475..>1484
                     /note="pro-peptide"
                     /product="cathepsin L"
                     /codon_start=1
                     /translation="MNP"
BASE COUNT      334 a    391 c    416 g    343 t
ORIGIN      
        1 agaaccgcga cctccgcaac cttgagcggc atccgtggag tgcgcctgca gctacgaccg
       61 cagcaggaaa gcgccgccgg ccaggcccag ctgtggccgg acagggactg gaagagagga
      121 cgcggtcgag taggtgtgca ccagccctgg caacgagagc gtctaccccg aactctgctg
      181 gccttgaggt ggggaagccg gggagggcag ttgaggaccc cgcggaggcg cgtgactggt
      241 tgagcgggca ggccagcctc cgagccgggt ggacacaggt accgcagcca ggccggcgcc
      301 aacgactcag ggcctggccc ggccagacag ggaagctcag tccccgcacg ccagacagcg
      361 gtactcctgc tggcgtcacc gcaaacatcc tctgaccgct acagccagtg tgtgggcagg
      421 cgtcatgtcc ccggccctgc cacgcctgga gccctggaag ctggctgcag ggctctggct
      481 tcccgcgtgc gcccatatga ccccgtccct gatttagggg agcagtttgg ggtgtcggca
      541 gcacaggccc aagtgaatga aggagggaag cagtgcgtgc tctccttccc agtttttcct
      601 gggaaagcat ttcagaaagg tttcatttaa gaagaggttg gggcggccag gtggctcact
      661 cctgtaatcc cagcactttg ggaggctgag gtgggcggat cacctgaggt cagtagttca
      721 gaccagcctg gccaacatgg tgaaaccccg tctctactga aaatacaaaa ttagacgggc
      781 gaggcggcgc acgcctgtag ttccagctat tcaagaggct gaggaagaat ggcttgaacc
      841 cgggaggcag aggttgctgt gagtcgatat cgcgccgttg aactccagcc tgggccacag
      901 agcaagactc catctcaaaa aataaataaa taaataaata aataaataaa taggagagat
      961 tggaaaactt atctcagctt ttggtgtttg ttagtcagga agatgtgtga aggcctccta
     1021 actcttgggg atctctttgt cccctacttg ggaatcccac cttatcatta gtgaggtttt
     1081 gcctgggcac gaaacctgga ttttttgcga ttggtacaaa acctggatca accgtttccc
     1141 ggtttcctag ttgttgcctt aagcttctca cacacaaggt agtttcatac ggttctcata
     1201 acctaaattg tcatcgcata aactgtttca gctcctacag ctctggacag gctgcttttc
     1261 attttggtaa gtccatccag tacctccacg tgccctgttt ttctccaggc acatccttgg
     1321 cctcttccac agtccttggg taaatgcttg ggagaataat ttaaatattt ttattctacc
     1381 atggtggccc taatttttca gggggcagta agatggcttt ttaggattgg tctaatcaga
     1441 tcctcatttt tgttcccttc ctaggtttta aaacatgaat ccta
//