From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: P.troglodytes immunoglobulin alpha-2 constant region gene for
Date: 28 Jul 92 10:02:40 GMT
Distribution: bionet
Checksum: 38786     7

LOCUS       CHPIGA2C     2731 bp ds-DNA             PRI       28-JUL-1992
DEFINITION  P.troglodytes immunoglobulin alpha-2 constant region gene for
            alpha-immunoglobulin heavy-chain constant region
ACCESSION   X53706
KEYWORDS    direct repeat; hinge region; immunoglobulin alpha-2;
            immunoglobulin-alpha heavy-chain constant (C) region.
SOURCE      Pan troglodytes DNA.
  ORGANISM  Pan troglodytes
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Pongidae.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Kawamura,S., Tanabe,H., Watanabe,Y., Kurosaki,K., Saitou,N.,
            Omoto,K. and Ueda,S.
  JOURNAL   Mol. Biol. Evol. 8, 793-793 (1991)
  STANDARD  simple staff_entry
COMMENT     *source: cell_type=leucocyte; *source: clone_library=genomic;
            *source: clone=lambda L.P.Ig epsillon.18; *source: is_germline=Y;
            Related sequence: X08040
            From EMBL    entry PTIGA2C;  dated 29-NOV-1991.
FEATURES             Location/Qualifiers
     5'UTR           <1..290
     mRNA            join(291..596,811..1131,1354..1748)
                     /gene="immunoglobulin alpha-2 constant region"
     CDS             join(291..596,811..1131,1354..1748)
                     /product="alpha-immunoglobulin heavy-chain constant
                     region"
                     /gene="immunoglobulin alpha-2 constant region"
                     /codon_start=3
                     /translation="SPTSPKVFPLSLDSNPQDGNVVVACLVQGFFPQEPLSVTWSESG
                     QNVTATNFPPSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVTHYTNPSQDVTVPCRV
                     PPPPPCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGATFTWTPPSGKSAVQGP
                     PERDLCGCYSVSSVLPGCAQPWNHGETFTCTAAHPELKNPLTANITKSGNTFRPEVHL
                     LPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTT
                     TYAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHINVSVVMAEV
                     DGTCY"
                     /partial
     exon            291..596
                     /number=1
                     /note="CH1"
     intron          597..810
                     /number=1
     repeat_region   797..811
                     /rpt_type=direct
                     /note="hinge region"
     exon            811..1131
                     /number=2
                     /note="CH2"
     repeat_region   812..826
                     /rpt_type=direct
                     /note="hinge region"
     intron          1171..1391
                     /number=2
     exon            1354..1748
                     /number=3
                     /note="CH3"
     polyA_signal    1773..1778
BASE COUNT      537 a    914 c    822 g    458 t
ORIGIN
        1 gagctcaggg gactcagcca ctccatggca gagccctgtt taatataact tgtgtctggg
       61 atggcctggg tcagaggccc tatctaagga gcatgttcag aaaccgtgtc gctgggatga
      121 gacagctggg tccaaccgca ggcccatggt gcaggagctg tgtgaccttg gggctgtcac
      181 caggcctctc tgtgctgggt tcctccagta tagaggagag gcaggcacag cctgtcctcc
      241 tggggacatg gcatgatggc cgcgtcctca cagcgcattc tgtgttccag catccccgac
      301 cagccccaag gtcttcccgc tgagcctcga cagcaacccc caagatggga acgtggtcgt
      361 cgcctgcctg gtccagggct tcttccccca ggagccactc agtgtgacct ggagtgaaag
      421 cggacagaac gtgaccgcca caaacttccc acccagccag gatgcctccg gggacctgta
      481 caccacgagc agccagctga ccctgccggc cacacagtgc ctagccggca agtccgtgac
      541 atgccacgtg acgcactaca cgaatcccag ccaggatgtg actgtgccct gccgaggtca
      601 gagggcaggc tggggagtgg ggcggggcca ccccgtcctg ccctgacact gcgcctgcac
      661 ccgtgttccc cacagggagc cgccccttca ctcacaccag agtggactgc gggccgagcc
      721 ccaggaggtg gtggtggaca ggccaggagg ggagaggcgg gggcatgggg aagggcgttc
      781 tgaccagctc aggccatctc tccactccag ttcccccacc tcccccatgc tgccaccccc
      841 gactgtcgct gcaccgaccg gccctcgagg acctgctctt aggttcagaa gcgaacctca
      901 cgtgcacact gaccggcctg agagatgcct ctggtgccac cttcacctgg acgcccccaa
      961 gtgggaagag cgctgttcaa ggaccacctg agcgtgacct ctgtggctgc tatagtgtgt
     1021 ccagtgtcct gcctggttgt gcccagccat ggaaccatgg ggagaccttc acctgcactg
     1081 ctgcccaccc cgagttgaag aacccactaa ccgccaacat cacaaaatcc ggtgggtcca
     1141 gaccctgctc ggggctctgc tcagtgtcct ggtttgcaaa gcatattccc agcctgcctc
     1201 ctccctccca atcctgggct ccagtgctca tgccaagtac agagggaaac tgaggcaggc
     1261 tgaggggcca ggacacagcc cggggtgccc accagagcag aggggctctc tcatcccctg
     1321 cccagccccc tgacctggct ctctaccctc caggaaacac gttccggccc gaggtccacc
     1381 tgctgccgcc gccgtcggag gagctggccc tgaatgagct ggtgacactg acgtgcctgg
     1441 cacgcggctt cagccccaag gacgtgctgg ttcgctggct gcaggggtca caggagctgc
     1501 cccgcgagaa gtacctgact tgggcatccc ggcaggagcc cagccagggc accaccacct
     1561 acgctgtaac cagcatactg cgcgtggcag ctgaggactg gaagaaaggg gacaccttct
     1621 cctgcatggt gggccacgag gccctgccgc tggccttcac acagaagacc atcgaccgcc
     1681 tggcgggtaa acccacccac atcaatgtgt ctgttgtcat ggcggaggtg gacggcacct
     1741 gctactgagc cgcccgcctg tccccacccc tgaataaact ccatgctccc ccaagcagcc
     1801 ccacgcttcc atccggcgcc tgtctgtcca tcctcagggt ctcagcactt gggaaagggc
     1861 cagggcatgg acagggaaga atacaccctg ccctgagcct cggggggccc ctggcacccc
     1921 catgagcctt tccaccctgg tgtgagtgtg agttgtgagt gtgagagtgt gtggtgcagg
     1981 aggcctcgct ggtgtgagat cttaggactg ccgaggcagg cacagtgcag gatgggttct
     2041 gagagacgca catgccccgg agagttctga gtgagcagtg gcacggccgt ttgtccctga
     2101 gagagccacc tctggctgca gctgggaggg aatagggagg gtaaaaggag caggctagcc
     2161 aagaaaggcg caggtagtgg gaggagcagc gagggagtga ggggctggac tccaggaccc
     2221 cactgggagg acaagctcca ggagggcccc accaccctag tgggtgggcc tcaggacgtc
     2281 ccactgacgc atgcaggaag gggcacctcc ccttaaccac actgctctgt acggggcacg
     2341 tgggcacacg tgcacactca cactcacata tacgcctgag ccctgcagga gcggaacatt
     2401 cacagcccag acccagttcc agaaaagcca ggggagtccc ctcccaagcc cccacgctca
     2461 gcctgctccc ccaggctcct ctggcttccc tgtgtttcca ctgtgcacag ctcagggacc
     2521 aactccacag acccctccca ggcagcccct gctccctgcc tggccaagtc tcccatccct
     2581 tcctaagccc aactaggacc caaagtatag acagggaggg gccgcgtggg gtggcatcag
     2641 aagcaggcca gtgagacagg gcctgcccag ggccctctgc atgcctctgg cttctgcctg
     2701 gggctcccag gagtggaaga acagtcccac a
//