From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human cytoplasmic acid phophatase B (ACP1) gene exons 2-3;
Date: 21 Dec 92 20:43:57 GMT
Distribution: bionet
Checksum: 00511 4

LOCUS       HUMACP1BAB    526 bp ds-DNA             PRI       17-NOV-1992
DEFINITION  Human cytoplasmic acid phophatase B (ACP1) gene exons 2-3;
            cytoplasmic acid phophatase A (ACP1) gene.
ACCESSION   L06508
KEYWORDS    acid phosphatase 1; cytoplasmic acid phophatase A;
            cytoplasmic acid phophatase B; glycerophosphatase;
            phosphomonoesterase.
SOURCE      Homo sapiens female blood DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Sensabaugh,G.F., Lazaruk,K.D. and Dissing,J.
  TITLE     Exon Structure at the ACP1 Locus Supports an Alternative Splicing
            Mechanism for the Generation of Izozymes
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     intron          <1..192
                     /number=1
                     /function="cytoplasmic acid phosphatase B"
                     /standard_name="ACP1*B"
                     /note="This intron is approximately 1.8Kb. The entire
                     intron hasnot been sequenced."
                     /gene="ACP1"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
     exon            193..298
                     /number=2
                     /EC_number="3.1.3.2"
                     /standard_name="ACP1*B"
                     /gene="ACP1"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
     allele          replace(216,"a")
                     /frequency=0.35
                     /phenotype="ACP1*A cytoplasmic acid phosphatase isozyme"
                     /standard_name="cytoplasmic acid phosphatase A"
                     /gene="ACP1*A"
                     /label=A-isozyme
                     /citation=[1]
     intron          299..439
                     /number=2
                     /standard_name="ACP1*B"
                     /gene="ACP1"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
     exon            440..514
                     /number=3
                     /standard_name="ACP1*B"
                     /gene="ACP1"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
     3'UTR           515..526
                     /standard_name="ACP1*B"
                     /gene="ACP1"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
BASE COUNT      151 a     95 c    114 g    158 t      8 others
ORIGIN      
        1 cttgcctaga gagagggcag tggcatacag ctgcagaagg ggccacacgg gcctgctgag
       61 tgntccgttt catttcaaat taggtcattc tgncntgatt ttgatatgga tgtttcagaa
      121 gaccctagca gatgnccctg tttaacntga aaccntagat cagaaaacta agttcatatt
      181 tcaattttac agagatttga atagaaaaag taatcaagtt aaaacctgca aagctaaaat
      241 tgaactactt gggagctatg atccacaaaa acaacttatt attgaagatc cctattatgt
      301 aagtacagtt cacgttttag ggctaatatg aagacccaac acatttgtat cctgccatat
      361 taaataacag atgagattgt gttaaggatg tttttgttat gcaggttttg ccattttctt
      421 ctttttcctg tccatttagg ggaatgactc tgactttgag acggtgtacc agcagtgtgt
      481 caggtgctgc agagcgttct tggagaannc ccactgaggc aggttc
//