From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.norvegicus CYP3A1 gene for cytochrome P450 PCN1
Date: 4 Sep 92 10:06:29 GMT
Distribution: bionet
Checksum: 02149     5

LOCUS       RATCYP3A1    2073 bp ds-DNA             ROD       04-SEP-1992
DEFINITION  R.norvegicus CYP3A1 gene for cytochrome P450 PCN1
ACCESSION   X62086
KEYWORDS    CYP3A1 gene; Cytochrome P450 PCN1;
            NADP dependent cytochrome P450 reductase;
            dexamethosone-induced cytochrome P450; monoxygenase;
            phenobarbital-induced cytochrome P-450.
SOURCE      Rattus norvegicus DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2073)
  AUTHORS   Telhada,M.B., Pereira,T.M. and Lechner,M.C.
  TITLE     Effect of dexamethasone and phenobarbital on run-on transcription
            rate and CYP3A mRNA concentration in rat liver: changes during
            development
  JOURNAL   Arch. Biochem. Biophys. (1992) In press
  STANDARD  full automatic
COMMENT     *source: strain=Wistar; *source: stage=adult; *source: tissue=
            liver; *source: clone_library=genomic: EMBL3cosW; *source: clone=
            pBluescript II SK +/- CYP3A1;
            For related sequences see X62087, M10161, Gonzalez F.J.; Mol.Cell
            Biol 6:2969-2976 (1986) & Yanagida A.; Mol.Cell Biol. 10:
            1470-1475(1990).
            From EMBL    entry RNCYP3A1;  dated 10-AUG-1992.
FEATURES             Location/Qualifiers
     misc_feature    complement(551..562)
                     /note="Basic transcription element"
     TATA_signal     1367..1371
     exon            1398..1557
                     /number=1
     mRNA            1398..1557
                     /partial
                     /note="product EC numberis 1.14.14.1"
                     /gene="CYP3A1"
BASE COUNT      471 a    500 c    474 g    628 t
ORIGIN
        1 ccaaaaaaag cccgctcatt aggcggcgtg gcctcgatgg ccatttaggt gacactatag
       61 aagggacgac actcgaggga tcttgtgcac ttttctcctc tggtttacaa ccgtcatctt
      121 tctctgactt tctttgtttc ttccccgttg ctttagtctt tgcagaagac gtgctcggtt
      181 ggctagacat ctggcattcc acttcttccc ttggctcctc tgcacgcccc ttcttgcttc
      241 cagacggctc catcttgaat ttagatgaga cctccgaaag aaagttctcc taagcttccc
      301 ttccacagga gtcttagagc ttccctgatg tttgactgtg gctctctgta tgtcagttcc
      361 cccacctctc tctgtgtgga atgaatttcg cccccctctt atcccacccc cgtaaacctc
      421 agttcttccc tgcaaatctt cttcccacat tcacgacttg tttcatgtcc taaggacatt
      481 atctagtgcc atgtgcgtga ctgtgagttt ggaagcctgc gggtcaccag tgggttcaca
      541 actgagtaca attcctcctt ctctcattag gcagcaatga gtgtcaggcc ctgtctcttt
      601 ctcactggca ccaaagggtg gcaggtgttg aattttggtg gatagatata gtagaggaat
      661 atttctttgt gagtctgtgt cttccatatc ccaggcttgt ctcaaacact ctatgttgct
      721 ttgaactttg tctttgaact tctgatgccc ctgcctctgc tctgtaagtg caggattgca
      781 gaagtctatt acttatgata gtacactggg gatagagcca gagttctgtg actgctaagc
      841 agaatgtctc tccaccaact gatccttatc attactccta gcgtttcttt ttcttttttc
      901 acaaagaagc actcatcatg agtgctggac agtgcctcag gggttgagtg ggcttttgca
      961 cttctggaga actggtgctt gattcctaga cattacagtg gagatatagg tccttgagca
     1021 gctccagtat ttttcagtga aggagaaagt ccttctgtaa tggtgtgcag atgacacagt
     1081 tttggcttaa tttcatgaag atttgaatga agtcagcctt ggtgagagat tattttatat
     1141 tatcgaattt gcttgaattt ctgatagaaa caatctaaga aactttggtc ttacttatat
     1201 ggcactgttg ttcactgacg ccacccacaa tgttaactca aaggaggtca aaataggctg
     1261 tagatgaact tcatgaactg tctaggggaa gagagtacca aagtccacgt gaggcagagg
     1321 tgatccatct actggctgga tcctggtgcc acccatcttt ccagcatata agtactgcag
     1381 gctggcctca gtgcagcggt gtgggcagaa aggaagccct gcagagcatc agaggcccag
     1441 ctagagggac aacacagagg agtaatttgc tgacagacct gcagggatgg acctgctttc
     1501 agctctcaca ctggaaacct gggtcctcct ggcagtcgtc ctggtgctcc tctacgggtg
     1561 agtgacttca gaagttcccc ctgcgaccag gttcttgggt ttgaagttat attcagacct
     1621 gaactttttt attattgggt ggctcaaact ggtaccagaa tcaggctgga gtgatgatgg
     1681 ctccgtgttt aaggccagtg gctgctcttc agaggatcac tatttgaacc ccaacatcca
     1741 catgcaactc acagtcatct gtaactatgg ctaaaggtga tctgacacct tccacaggca
     1801 agctaggatg ggactgaaag gcggcagttt tctaatctgg ctaactccta aataattaaa
     1861 agagaggact attaagttta ttagcaagct ttaaggacta tgacggggca ggttctaagc
     1921 tattcttacc cacaaagctc tctcaaccat agtccccaaa tacttgcagt gtgacttttt
     1981 ccctgggttg ctctgttccg tgtgtgtcct catggtaagc tcccttggtg aatccttctc
     2041 atgcctgctt ttgtggtgtc cttgttcttc ctc
//