From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus c-kit mRNA for truncated tyrosine-kinase
Date: 15 Aug 92 10:02:27 GMT
Distribution: bionet
Checksum: 30650     6

LOCUS       MUSCKITM     3166 bp ss-RNA             ROD       15-AUG-1992
DEFINITION  M.musculus c-kit mRNA for truncated tyrosine-kinase
ACCESSION   X65997
KEYWORDS    c-kit gene; proto-oncogene; protooncogene c-kit;
            tyrosine kinase receptor.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3166)
  AUTHORS   Rossi,P., Marziali,G., Albanese,C., Charlesworth,A., Geremia,R. and
            Sorrentino,V.
  TITLE     A novel c-Kit transcript, potentially encoding a truncated
            receptor, originates within a kit gene intron in mouse spermatids.
  JOURNAL   Dev. Biol. (1992) In press
  STANDARD  full automatic
COMMENT     *source: strain=ICR;
            From EMBL    entry MMCKITM;  dated 06-AUG-1992.
FEATURES             Location/Qualifiers
     prim_transcript 1..3166
     CDS             416..1024
                     /note="germ cell specific c-kittranscript 3.2kb"
                     /product="truncated tyrosinekinase receptor"
                     /gene="c-kit"
                     /codon_start=1
                     /translation="MAVAVFPFLPQQCIHRDLAARNILLTHGRITKICDFGLARDIRN
                     DSNYVVKGNARLPVKWMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDS
                     KFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISDSTKHI
                     YSNLANCNPNPENPVVVDHSVRVNSVGSSASSTQPLLVHEDA"
BASE COUNT      800 a    712 c    727 g    927 t
ORIGIN
        1 attcccaggt aactaccaag ctaaaagaca ggctgaaatg aaagaccctc ttccttgtgt
       61 ccttgggaga agacgtcaag ttgaagctgt gaaacttttt tttttttttt ttttggagaa
      121 aacgttcaaa gagatgcata caaaatgaac tttcatttta gaaatgggat ttgactattt
      181 ataatgcatt ttcctgtgaa tggaaggaag ggagaaagac gtttattaaa attgggttgg
      241 aaagcaatta tagtcattag agccccgatc ctgtgaaaca caaaacggga atatcacttg
      301 caccataatt tttattttcg gtgtgctaaa tactttaaaa cgaaagtttc tttttttttt
      361 tcatgtaaac accattgtag tattaaaatc atcttctctc ggagagctga aatgaatggc
      421 tgttgctgtc tttccttttc tcccccaaca gtgtattcac agagatttgg cagccaggaa
      481 tatcctcctc actcacgggc ggatcacaaa gatttgcgat ttcgggctag ccagagacat
      541 caggaatgat tcgaattacg tggtcaaagg aaatgcacga ctgcccgtga agtggatggc
      601 accagagagc attttcagct gcgtgtacac atttgaaagt gatgtctggt cctatgggat
      661 tttcctctgg gagctcttct ccttaggaag cagcccctac ccagggatgc cggtcgactc
      721 caagttctac aagatgatca aggaaggctt ccggatggtc agcccggagc acgcgcctgc
      781 cgaaatgtat gacgtcatga agacttgctg ggacgctgac cccttgaaaa ggccaacatt
      841 caagcaggtt gtccaactta ttgagaagca gatctcggac agcaccaagc acatttactc
      901 caacttggca aactgcaacc ccaacccaga gaaccccgtg gtggtggacc attccgtgag
      961 ggtcaactcg gtgggcagca gcgcctcttc tacgcagccc ctgctcgtgc acgaagatgc
     1021 ctgagcagaa acccaagtcc aacaggcttt gctgctgtct ccgaccccgt ccttctggct
     1081 tctgtgatgg ttacttggtt tccctttgac ttgcatccta ttccagggta gcgagttccc
     1141 caccccacct ccaaccccac tgtgattccg cctttacgag cacacacttt agtggccgat
     1201 ggcttttctt ttctgccatc agccaccgtc ccgctgcgaa ggtccgaact gtatgtatat
     1261 attttcccaa tagcaaagta gctcctactg taaacagaag gactcctcct gctttagagg
     1321 agaagggaag ggcggggtga aactggatgc ccagagttct tcccccagtg ctcccctgag
     1381 tgtatttgaa aagtatggcc agtagttcac ttgaagaata gatgtagtcc catttggccc
     1441 tgagagccat ccttaatgat gggagatata tgtagcaaga ctagaaagcc aagccctttg
     1501 tgtagaaagc agaccattct tagaacagag ggcaacgggg catcggaagt ctggtcacgc
     1561 taagaagacc gaggctgaga aggaacaagc caggggaagc gtgaacaatg atgctctgct
     1621 ctgggctgcc gctcgggctt ctgtacaact gacctggttt ctcagtactt tgctgtctgg
     1681 gagtagcatt ggaatcaagg cctcctccct agtcagcctt tgtatatact catctatacg
     1741 ttgtatgcgt tcatactttg gaggagggat ttcccacaag ctttcgtttc tgtgtacagc
     1801 cctggattag acctactgtg tgtaagaata gattaagagc catacatatt tgaaggaaac
     1861 agttaaatgt tttttggttg tggttgttgt tgttgttgtt ttaaagaaaa aaatgtatat
     1921 gctaagcaca atctttataa gacctcttag ccaacatact tgctctgtct acacttcgga
     1981 acaagccttc catgtcagag tggctttgca ggcaggagaa ctgaggctgt ttgaaaaggt
     2041 taccacagga tggagaaaac agtgcagtcc tggtttggat tctcacatag cagggagcac
     2101 aagttaaact cgacctttta taggcacgtc ccggacatcg ggcctgtatc tattcaagtg
     2161 tgtatgtgtg tgcatgcgtg tgtctatgcg tgtgggtgag ttgtgttggg aaacttgccc
     2221 tgcatccctg agggtcctcc ttcaggaccc aagacgtaac agcttctgtc accgctcctg
     2281 tctctccagt ttccctgcat gtcgctcact gtctagaatt tactcaaagc cgccacagag
     2341 gcttagcgga gtgaagtgcc gaaggacctc tttatttgga gtcctcctgt atttaacaac
     2401 actcttatcg tagacccatt cattagacct tatgtaatgc tgccaatcca gggaaacaga
     2461 tttaaagtgt accccgtaga cagggcccag aggttccctt gtccttgccc tcccccacac
     2521 cacccatgat cactgtccaa cataaagggt tcagtgtgtt acgtggtcat gtgttgtcct
     2581 tacaggattc aggtatgttg ccttcacggt tttccccacc ccctcctgcc ctttatcctt
     2641 taggccgtgt ggccatgaac ctggaagaag tgatcgtttc gacttgagtg ctacactctt
     2701 gcacctttcc aaagtaagct ggtttggagg tcctgtggtc atgtacgaga ctgtcaccag
     2761 ttaccgcgct ctgtttgaaa catgtctttg tattcctaat gacttcagtt agagtaagga
     2821 gaatagctgt taatatggat gtcaggtact taaggggcca caccattgag aattttgtct
     2881 tggatattct tgaaagttta tatttttata atttttttta catcagatgt cagatgtttc
     2941 tttcagttgc ttgatgtttg gaattattat gtggcttttt ttgtaaatat tgaaatgtag
     3001 caataatgtc ttttgaatat tcctgagccc atgagtccct gaaaatattt tttatatata
     3061 cagtaacttt atgtgtaaat aatacgctgt gcaagtttaa acatgtcacg ttacatgtgg
     3121 gttttttctg atatgttgtc caactgttga cagttctgaa gaattc
//