From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens alpha-1 strychnine binding subunit of inhibitory glycine
Date: 3 Jan 93 22:06:32 GMT
Distribution: bionet
Checksum: 33230 5

LOCUS       HUMGLYRA1    1857 bp ss-RNA             PRI       21-DEC-1992
DEFINITION  H.sapiens alpha-1 strychnine binding subunit of inhibitory glycine
            receptor mRNA
ACCESSION   X52008
KEYWORDS    glycine receptor; inhibitory glycine receptor; strychnine binding.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Grenningloh,G., Schmieden,V., Schofield,P.R., Seeburg,P.H.,
            Siddique,T., Mohandas,T.K., Becker,C.M. and Betz,H.
  TITLE     Alpha subunit variants of the human glycine receptor: primary
            structures, functional expression and chromosomal localization of
            the corresponding genes
  JOURNAL   EMBO J. 9, 771-776 (1990)
  STANDARD  full automatic
COMMENT     *source: stage=fetal; *source: tissue=brain;
               From EMBL    entry HSGLYRA1;  dated 17-DEC-1992.
FEATURES             Location/Qualifiers
     CDS             388..1746
                     /gene="GLYRA1"
                     /note="strychnine binding alpha-1 subunit"
                     /product="inhibitory glycine receptor"
                     /codon_start=1
                     /translation="MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSP
                     SDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQW
                     NDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKV
                     LYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTL
                     PQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSF
                     WINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLE
                     YAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKAT
                     PANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVH
                     KK"
BASE COUNT      526 a    416 c    417 g    498 t
ORIGIN      
        1 ggctttgcta aacagaaaag atataaaaca aaagccacag ctatctagca tggcattgtc
       61 accaactccc tttgcatggt gatgcgatta aggtagcagc atttttatta ttcaggaaaa
      121 gcagctgggg gattcatcag ttctgaggct ttgtctttct gggttaactg atggtcccaa
      181 gcctcggttt gacctgacca tgatgcccag gactggcact ttttcttttt tctcagcaaa
      241 ctgtacaaaa ccaaatctct ttttgatttt caaggaaact aggttcctgc caaattttga
      301 ttgaatctgg acaataaaca gacactttgt cctagcatct ttctggaatc atttcgggat
      361 atttccacaa gcaacacaga aacaggaatg aaccggcagc tagtgaacat tttgacagcc
      421 ttgtttgcat ttttcttaga gacaaaccac ttcaggacgg ctttctgcaa agaccatgac
      481 tccaggtctg gaaaacaacc ttcacagacc ctatctcctt cagatttctt ggacaagtta
      541 atgggaagga catcaggata tgatgcaaga atcaggccaa attttaaagg tcctccagta
      601 aacgttactt gcaatatttt tatcaacagt tttggatcag tcacagaaac gaccatggac
      661 taccgagtga atatttttct gagacaacag tggaatgatt cacggctggc gtacagtgag
      721 tacccagatg actccctgga cttggaccca tccatgctag actccatttg gaaaccagat
      781 ttgttctttg ccaatgagaa gggtgccaac ttccacgatg tcaccactga caacaaattg
      841 ctacggattt cgaaaaatgg caaagtgctc tacagtatca gactcacctt gaccttatcc
      901 tgtcccatgg acttgaagaa ctttccgatg gatgtccaga cctgtacaat gcagctggag
      961 agttttgggt acacgatgaa tgacctgata tttgagtggt taagtgatgg tccagtgcaa
     1021 gttgctgaag gattgaccct gccccagttt attttgaaag aagagaagga acttggctac
     1081 tgtacaaagc actacaacac tggaaagttt acctgcattg aggtcaagtt tcacctggaa
     1141 cgccaaatgg gatattattt gatccagatg tacatcccaa gcctgcttat agtaattttg
     1201 tcctgggttt ccttttggat aaatatggat gcagcccctg ccagggtcgc actgggcatc
     1261 accacagtct taacgatgac cacccagagt tcaggctcca gggcatctct gccaaaggtc
     1321 tcctatgtaa aagcgattga catctggatg gcggtgtgcc ttctgtttgt gtttgctgcc
     1381 ttactggaat acgcagcggt gaacttcgtc tccaggcaac acaaggagtt cctgcgcctc
     1441 cgaagaagac agaagaggca gaataaggaa gaagacgtta ctcgtgaaag tcgttttaat
     1501 tttagcggtt atgggatggg tcactgcctc caagtgaaag atggaacagc tgtcaaggcc
     1561 acacctgcca acccactccc acaaccgcca aaagatggag atgctatcaa gaagaagttt
     1621 gtggaccggg caaaaaggat tgacacgata tctcgagctg ccttcccatt ggccttcctc
     1681 attttcaaca tcttttactg gatcacatac aagatcattc ggcatgaaga tgtccacaag
     1741 aaatagatgt gccctacaga ccctgggacc ttcttgcctc agtgttgtgc ttgtaaatac
     1801 acagtgaaat tgtctttata tcactttgac agaggagaag attgagggag gggggag
//