From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human lamin B mRNA, complete cds.
Date: 24 Jul 92 10:06:42 GMT
Distribution: bionet
Checksum: 31277     6

LOCUS       HUMLAMBA     2850 bp ss-mRNA            PRI       24-JUL-1992
DEFINITION  Human lamin B mRNA, complete cds.
ACCESSION   M34458
KEYWORDS    intermediate filament; lamin B.
SOURCE      Human T-cell line MOLT-4, cDNA to mRNA, clone LAM-2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2850)
  AUTHORS   Pollard,K.M., Chan,E.K., Grant,B.J., Sullivan,K.F., Tan,E.M. and
            Glass,C.A.
  TITLE     In vitro posttranslational modification of lamin B cloned from a
            human T-cell line
  JOURNAL   Mol. Cell. Biol. 10, 2164-2175 (1990)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     mRNA            <342..2850
                     /note="lamin B mRNA"
     CDS             342..2101
                     /note="lamin B"
                     /codon_start=1
                     /translation="MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLA
                     VYIDKVRSLETENSALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAK
                     LQIELGKCKAEHDQLLLNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLE
                     GDLEDLKDQIAQLEASLAAAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINE
                     TRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENAR
                     LSSEMNTSTVNSAREELMESRMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDN
                     SRRMLTDKEREMAEIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSP
                     SPSSRVTVSRASSSRSVRTTRGKRKRVDVEESEASSSVSISHSASATGNVCIEEIDVD
                     GKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTAS
                     PPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTIPEEEEEEEEAAGVVVE
                     EELFHQQGTPRASNRSCAIM"
                     /partial
     polyA_signal    2834..2839
BASE COUNT      776 a    614 c    748 g    712 t
ORIGIN
        1 cgcgagcagg agacggcggc gggcgaaccc tgctgggcct ccagtcaccc tcgtcttgca
       61 ttttcccgcg tgcgtgtgtg agtgggtgtg tgtgttttct tacaaagggt atttcgcgat
      121 cgatcgattg attcgtagtt cccccccgcg cgcctttgcc ctttgtgctg taatcgagct
      181 cccgccatcc caggtgcttc tccgttcctc taaacgccag cgtctggacg tgagcgcagg
      241 tcgccggttt gtgccttcgg tccccgcttc gccccctgcc gtcccctcct tatcacggtc
      301 ccgctcgcgg cctcgccgcc ccgctgtctc cgccgcccgc catggcgact gcgacccccg
      361 tgccgccgcg gatgggcagc cgcgctggcg gccccaccac gccgctgagc cccacgcgcc
      421 tgtcgcggct ccaggagaag gaggagctgc gcgagctcaa tgaccggctg gcggtgtaca
      481 tcgacaaggt gcgcagcctg gagacggaga acagcgcgct gcagctgcag gtgacggagc
      541 gcgaggaggt gcgcggccgt gagctcaccg gcctcaaggc gctctacgag accgagctgg
      601 ccgacgcgcg acgcgcgctc gacgacacgg cccgcgagcg cgccaagctg cagatcgagc
      661 tgggcaagtg caaggcggaa cacgaccagc tgctcctcaa ctatgctaag aaggaatctg
      721 atcttaatgg cgcccagatc aagcttcgag aatatgaagc agcactgaat tcgaaagatg
      781 cagctcttgc tactgcactt ggtgacaaaa aaagtttaga gggagatttg gaggatctga
      841 aggatcagat tgcccagttg gaagcctcct tagctgcagc caaaaaacag ttagcagatg
      901 aaactttact taaagtagat ttggagaatc gttgtcagag ccttactgag gacttggagt
      961 ttcgcaaaag catgtatgaa gaggagatta acgagaccag aaggaagcat gaaacgcgct
     1021 tggtagaggt ggattctggg cgtcaaattg agtatgagta caagctggcg caagcccttc
     1081 atgagatgag agagcaacat gatgcccaag tgaggctgta taaggaggag ctggagcaga
     1141 cttaccatgc caaacttgag aatgccagac tgtcatcaga gatgaatact tctactgtca
     1201 acagtgccag ggaagaactg atggaaagcc gcatgagaat tgagagcctt tcatcccagc
     1261 tttctaatct acagaaagag tctagagcat gtttggaaag gattcaagaa ttagaggact
     1321 tgcttgctaa agaaaaagac aactctcgtc gcatgctgac agacaaagag agagagatgg
     1381 cggaaataag ggatcaaatg cagcaacagc tgaatgacta tgaacagctt cttgatgtaa
     1441 agttagccct ggacatggaa atcagtgctt acaggaaact cttagaaggc gaagaagaga
     1501 ggttgaagct gtctccaagc ccttcttccc gtgtgacagt atcccgagca tcctcaagtc
     1561 gtagtgtacg tacaactaga ggaaagcgga agagggttga tgtggaagaa tcagaggcga
     1621 gtagtagtgt tagcatctct cattccgcct cagccactgg aaatgtttgc atcgaagaaa
     1681 ttgatgttga tgggaaattt atccgcttga agaacacttc tgaacaggat caaccaatgg
     1741 gaggctggga gatgatcaga aaaattggag acacatcagt cagttataaa tatacctcaa
     1801 gatatgtgct gaaggcaggc cagactgtta caatttgggc tgcaaacgct ggtgtcacag
     1861 ccagcccccc aactgacctc atctggaaga accagaactc gtggggcact ggcgaagatg
     1921 tgaaggttat attgaaaaat tctcagggag aggaggttgc tcaaagaagt acagtcttta
     1981 aaacaaccat acctgaagaa gaggaggagg aggaagaagc agctggagtg gttgttgagg
     2041 aagaactttt ccaccagcag ggaaccccaa gagcatccaa tagaagctgt gcaattatgt
     2101 aaaattttca actgtcttcc tcaaaataaa gaagtatggt aatctttacc tgtatacagt
     2161 gcagagcctt ctcagaagca cagaatattt ttatatttcc tttatgtgaa tttttaagct
     2221 gcaaatctga tggccttaat ttcctttttg acactgaaag ttttgtaaaa gaaatcatgt
     2281 ccatacactt tgttgcaaga tgtgaattat tgacactgaa cttaataact gtgtactgtt
     2341 cggaaggggt tcctcaaatt ttttgacttt ttttgtatgt gtgttttttc ttttttttta
     2401 agttcttatg aggaggggag ggtaaataaa ccactgtgcg tcttggtgta atttgaagat
     2461 tgccccatct agactagcaa tctcttcatt attctctgct atatataaaa cggtgctgtg
     2521 agggagggga aaagcatttt tcaatatatt gaacttttgt actgaatttt tttgtaataa
     2581 gcaatcaagg ttataatttt ttttaaaata gaaattttgt aagaaggcaa tattaaccta
     2641 atcaccatgt aagcactctg gatgatggat tccacaaaac ttggttttat ggttacttct
     2701 tctcttagat tcttaattca tgaggagggt gggggaggga ggtggaggga gggaagggtt
     2761 tctctattaa aatgcattcg ttgtgttttt taagatagtg taacttgctt aaatttctta
     2821 tgtgacatta acaaataaaa aagctctttt
//