From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus (clone lambda-rat 1-2) heparin-binding EGF-like
Date: 6 Nov 92 18:34:36 GMT
Distribution: bionet
Checksum: 28892 4

LOCUS       RATHEPBIND   1550 bp ss-mRNA            ROD       02-NOV-1992
DEFINITION  Rattus norvegicus (clone lambda-rat 1-2) heparin-binding EGF-like
            growth factor mRNA, complete cds.
ACCESSION   L05389
KEYWORDS    EGF receptor ligand; heparin-binding EGF-like growth factor;
            mitogen; transmembrane precursor.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda-gt10)
            male adult peritoneum cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Abraham,J.A., Damm,D.L., Bajardi,A., Miller,J.A., Klagsbrun,M. and
            Ezekowitz,A.
  TITLE     Characterization of cDNA clones encoding rat and mouse
            heparin-binding EGF-like growth factor, and analysis of transcript
            expression in tissues
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..31
     sig_peptide     32..100
                     /codon_start=1
     mat_peptide     218..475
                     /product="heparin-binding EGF-like growth factor"
                     /codon_start=1
     3'UTR           659..1550
     CDS             32..658
                     /product="heparin-binding EGF-like growth factor"
                     /codon_start=1
                     /translation="MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAATSNPDPPT
                     GTTNQLLPTGADRAQEVQDLEGTDLDLFKVAFSSKPQALATPGKEKNGKKKRKGKGLG
                     KKRDPCLKKYKDYCIHGECRYLKELRIPSCHCLPGYHGQRCHGLTLPVENPLYTYDHT
                     TVLAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDLESEEKVKLGMASSH"
BASE COUNT      389 a    367 c    395 g    399 t
ORIGIN      
        1 gggccccccc gtctccgcca ggctcgggac catgaagctg ctgccgtcgg tggtgctgaa
       61 gctctttctg gccgcagtgt tgtccgcgtt ggtgaccggt gagagtctgg agcggcttcg
      121 gagaggtctg gcggcagcaa ccagcaaccc tgaccctccc actggaacca caaaccagct
      181 gctacccacg ggagctgatc gcgctcagga ggtccaggac ttggaaggga ccgatctgga
      241 ccttttcaaa gttgctttct cctccaagcc acaagccctg gccaccccag gaaaagaaaa
      301 gaacgggaaa aagaagagga aaggcaaggg gttaggaaag aagagagatc catgccttaa
      361 gaaatacaag gactactgca tccacggaga gtgcagatac ctgaaggagc tccgtattcc
      421 ctcgtgccac tgcctccctg gttaccatgg acagaggtgt catgggctga ccctaccggt
      481 agagaacccc ctgtacacat atgaccacac taccgtcttg gctgtggtgg ctgtagtact
      541 gtcatctgtc tgtcttcttg tcatcgtggg acttctcatg ttcaggtacc ataggcgagg
      601 aggttatgac ttggaaagtg aggagaaagt gaagttgggc atggctagct cccactgagg
      661 aggatctgag ctcaaggagc cttcagagga tggctacttc tgagatggcg gttccttaca
      721 agttctacag agggaaaata cttcaccagc agccatgaag acttcttcat tcattcccag
      781 ttgctaccct gactgggcct cctgtaattg ctctgcaaaa atatcagagc ctctaagtgc
      841 caaacagact atgccccgct gggatctgga tcagaagaaa gcaggagcaa gtgagccctt
      901 caggccttcc tgatcctcca ccactgaacc cactggtttg tttaaacact tagcttctgg
      961 attaaagtgt cagctagttt ccatatgctc caggattttt ggctgaaaaa aaaaaaagaa
     1021 gagaggacgg atgagtggtt tatggactgg aagagatcaa cagagttgag aagctaagtg
     1081 ttcaagtagc cacaggggat ctgctgtttg gaccctccag cacgctggat ttgatgagct
     1141 aactgtgaaa tatctcaagc ccgagaactc ttgagttttg ggacttctac ccagagggaa
     1201 aaataacaag tattttgttg ttgttgttgt ttgtttgttt ttaaaatgcc tcttaaatta
     1261 tatatttatt ttattctatg tatgttaata tatttagttt ttaacaatct aacaataata
     1321 tttcaagtgc ctagactgtt actttgccaa tgtcctggcc cgcctctctt gcagctcttc
     1381 cacctggctc aatgccacac tcccatctgc tctgtaaccc atctgtagta atttattgtc
     1441 tgtctacatt tcagaagatg cccctgtagc agagtatccc agggtgggtt gtgtatggtc
     1501 ggagtgcaag gatggatttg ggcagagcca ctctgtgagt tggactgcag
//