From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human carboxylesterase mRNA, complete cds.
Date: 29 Dec 92 21:27:11 GMT
Distribution: bionet
Checksum: 61040 5

LOCUS       HUMCOXYSA    1950 bp ss-mRNA            PRI       14-DEC-1992
DEFINITION  Human carboxylesterase mRNA, complete cds.
ACCESSION   L07764
KEYWORDS    carboxylesterase; glycosylation-dependent.
SOURCE      Homo sapiens (library: K19) liver cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1950)
  AUTHORS   Kroetz,D.L., McBride,O.W. and Gonzalez,F.J.
  TITLE     Glycosylation-Dependent Activity of Baculovirus-Expressed Human
            Liver Carboxylesterases: cDNA Cloning and Characterization of Two
            Highly Similar Enzyme Forms
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     polyA_signal    1926..1931
     CDS             46..1752
                     /citation=[1]
                     /note="putative"
                     /product="carboxylesterase"
                     /codon_start=1
                     /translation="MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGF
                     AQPVAIFLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELF
                     TNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAA
                     HENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTI
                     FGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCK
                     TTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPE
                     ELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCI
                     AKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEF
                     QYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNG
                     NPNGEGLPHWPEYNQKEGYLQIGANTQAGQKLKDKEVAFWTNLFAKKAVEKPPQTEHI
                     EL"
BASE COUNT      475 a    485 c    550 g    440 t
ORIGIN      
        1 ctgcacagag acctcgcagg ccccgagaac tgtcgccctt ccacgatgtg gctccgtgcc
       61 tttatcctgg ccactctctc tgcttccgcg gcttgggcag ggcatccgtc ctcgccacct
      121 gtggtggaca ccgtgcatgg caaagtgctg gggaagttcg tcagcttaga aggatttgca
      181 cagcctgtgg ccattttcct gggaatccct tttggcaagc cgcctcttgg acccctgagg
      241 tttactccac cgcagcctgc agaaccatgg agctttgtga agaatgccac ctcgtaccct
      301 cctatgtgca cccaagatcc caaggcgggg cagttactct cagagctatt tacaaaccga
      361 aaggagaaca ttcctctcaa gctttctgaa gactgtcttt acctcaatat ttacactcct
      421 gctgacttga ccaagaaaaa caggctgccg gtgatggtgt ggatccacgg aggggggctg
      481 atggtgggtg cggcatcaac ctatgatggg ctggcccttg ctgcccatga aaacgtggtg
      541 gtggtgacca ttcaatatcg cctgggcatc tggggattct tcagcacagg ggatgaacac
      601 agccggggga actggggtca cctggaccag gtggctgccc tgcgctgggt ccaggacaac
      661 attgccagct ttggagggaa cccaggctct gtgaccatct ttggagagtc agcgggagga
      721 gaaagtgtct ctgttcttgt tttgtctcca ttggccaaga acctcttcca ccgggccatt
      781 tctgagagtg gcgtggccct cacttctgtt ctggtgaaga aaggtgatgt caagcccttg
      841 gctgagcaaa ttgctatcac tgctgggtgc aaaaccacca cctctgctgt catggttcac
      901 tgcctgcgac agaagacgga agaggagctc ttggagacga cattgaaaat gaaattctta
      961 tctctggact tacagggaga ccccagagag agtcaacccc ttctgggcac tgtgattgat
     1021 gggatgctgc tgctgaaaac acctgaagag cttcaagctg aaaggaattt ccacactgtc
     1081 ccctacatgg tcggaattaa caagcaggag tttggctggt tgattccaat gcagttgatg
     1141 agctatccac tctccgaagg gcaactggac cagaagacag ccatgtcact cctgtggaag
     1201 tcctatcccc ttgtttgcat tgctaaggaa ctgattccag aagccactga gaaatactta
     1261 ggaggaacag acgacactgt caaaaagaaa gacctgttcc tggacttgat agcagatgtg
     1321 atgtttggtg tcccatctgt gattgtggcc cggaaccaca gagatgctgg agcacccacc
     1381 tacatgtatg agtttcagta ccgtccaagc ttctcatcag acatgaaacc caagacggtg
     1441 ataggagacc acggggatga gctcttctcc gtctttgggg ccccattttt aaaagagggt
     1501 gcctcagaag aggagatcag acttagcaag atggtgatga aattctgggc caactttgct
     1561 cgcaatggaa accccaatgg ggaagggctg ccccactggc cagagtacaa ccagaaggaa
     1621 gggtatctgc agattggtgc caacacccag gcgggccaga agctgaagga caaagaagta
     1681 gctttctgga ccaacctctt tgccaagaag gcagtggaga agccacccca gacagaacac
     1741 atagagctgt gaatgaagat ccagccggcc ttgggagcct ggaggagcaa agactggggt
     1801 cttttgcgaa agggattgca ggttcagaag gcatcttacc atggctgggg aattgtctgg
     1861 tggtgggggg caggggacag aggccatgaa ggagcaagtt ttgtatttgt gacctcagct
     1921 ttgggaataa aggatctttt gaaggccaca
//