From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human pancreatic lipase related protein 1 (PLRP1) mRNA, complete
Date: 4 Sep 92 10:04:16 GMT
Distribution: bionet
Checksum: 56921     4

LOCUS       HUMLRP1P     1481 bp ss-mRNA            PRI       04-SEP-1992
DEFINITION  Human pancreatic lipase related protein 1 (PLRP1) mRNA, complete
            cds.
ACCESSION   M93283
KEYWORDS    lipase related protein 1.
SOURCE      Homo sapiens pancreas cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1481)
  AUTHORS   Giller,T., Buchwald,P., Blum-Kaelin,D. and Hunziker,W.
  TITLE     Two novel human pancreatic lipase related proteins, hPLRP1 and
            hPLRP2: Differences in colipase dependence and in lipase activity
  JOURNAL   J. Biol. Chem. 267, 16509-16516 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     20..70
                     /gene="PLRP1"
                     /codon_start=1
     CDS             20..1423
                     /product="lipase related protein 1"
                     /gene="PLRP1"
                     /codon_start=1
                     /translation="MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKI
                     LPWSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDE
                     SWVTDMCKKLFEVEEVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSY
                     PPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVD
                     VIHTDAAPLIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDF
                     VACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAG
                     RTSEEQQKFFLNTGEASNFARWRYGVSITLSGRTATGQIKVALFGNKGNTHQYSIFRG
                     ILKPGSTHSYEFDAKLDVGTIEKVKFLWNNNVINPTLPKVGATKITVQKGEEKTVYNF
                     CSEDTVREDTLLTLTPC"
     mat_peptide     71..1420
                     /product="lipase related protein 1"
                     /gene="PLRP1"
                     /codon_start=1
     polyA_signal    1458..1464
                     /gene="PLRP1"
     polyA_site      1481
                     /gene="PLRP1"
BASE COUNT      399 a    371 c    379 g    332 t
ORIGIN
        1 ctctggaaca ttagacagga tgctgatctt ctggacaatc acacttttcc tgctgggagc
       61 agccaaagga aaagaagttt gctatgagga cctcgggtgc ttttctgaca ctgagccctg
      121 gggcgggaca gcaatcaggc ccctgaaaat tctcccctgg agccctgaga agatcggcac
      181 ccgcttcctg ctgtacacca atgaaaaccc aaacaacttt caaattctcc tcctctctga
      241 tccatcaaca attgaggcat caaattttca aatggacaga aagacccggt tcatcatcca
      301 tggcttcata gacaaaggag atgagagctg ggtgacagac atgtgcaaga aactgttcga
      361 ggtggaggag gtgaactgca tctgcgtgga ctggaagaag ggctcccaag ccacctacac
      421 acaggctgcc aacaacgtgc gagtggtggg cgcccaggtg gcccagatgc tcgacatcct
      481 cttgacagag tatagctacc ccccttccaa agttcacctc attggccaca gcctgggagc
      541 ccacgtggct ggagaggcag gaagcaagac tccaggcctg agcaggatta cagggttgga
      601 tcctgtagaa gcaagtttcg agagtactcc tgaagaggtg cgacttgatc cctctgatgc
      661 tgactttgtt gatgtgattc acacggatgc agctcccctg atcccattct tgggttttgg
      721 aacgaaccaa cagatgggtc atcttgactt cttccccaat ggaggagaga gcatgccggg
      781 atgcaagaag aatgccctgt ctcagatcgt ggatctagat ggcatctggg cgggaacccg
      841 ggactttgtg gcttgcaatc acctaagaag ctacaagtat tacttggaaa gcatcctcaa
      901 tcccgatggg tttgctgcat atccctgcac ttcctacaag tcctttgagt ctgacaagtg
      961 cttcccgtgt ccagatcaag gatgcccaca gatgggtcac tatgctgata aatttgctgg
     1021 caggacaagt gaagagcagc agaaattctt cttgaacaca ggagaggcta gcaatttcgc
     1081 tcgctggaga tatggggttt ccatcacact gtctggaaga acagccactg gtcagatcaa
     1141 agttgctttg tttggaaata agggaaacac tcaccagtac agcatcttca gggggattct
     1201 caaaccaggc tcaacccatt cctatgagtt tgatgcaaag ctggatgttg gaacaattga
     1261 gaaagtcaag tttctttgga ataacaatgt gataaatcca accctcccca aagtgggtgc
     1321 caccaagatc actgtgcaaa agggagaaga gaagacagtg tacaacttct gtagcgaaga
     1381 cacagtgcgg gaagacacgc tgctcaccct cacgccctgc taagctcccg gggcgacgag
     1441 gctgctgcgt tcacactaat aaaatccact ggtgcatctg t
//