From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human immunoglobulin germline lambda-chain gene variable region
Date: 29 Dec 92 19:58:07 GMT
Distribution: bionet
Checksum: 60407 4

LOCUS       HUMIGLVIV     836 bp ds-DNA             PRI       10-DEC-1992
DEFINITION  Human immunoglobulin germline lambda-chain gene variable region
            (subgroup IV), 5' end.
ACCESSION   M94113
KEYWORDS    germline; immunoglobulin lambda; immunoglobulin light chain;
            variable region; variable region subgroup lambda-IV.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (sites)
  AUTHORS   Daley,D.M., Peng,H.-q., Misener,V., Liu,X.-Y., Chen,P.P. and
            Siminovitch,K.A.
  TITLE     Molecular analysis of Human immunoglobulin Vlambda germline genes:
            Subgroups Vlambda III and Vlambda IV
  JOURNAL   Mol. Immunol. 29, 1515-1518 (1992)
  STANDARD  full automatic
COMMENT     Reference [Mol. Immunol. (1992) In press] reports bases 41 through
            976.
FEATURES             Location/Qualifiers
     misc_feature    181..671
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="IGLV"
     sig_peptide     join(181..226,373..383)
                     /gene="IGLV"
                     /codon_start=1
     promoter        85..92
     TATA_signal     113..119
     intron          227..372
     mat_peptide     384..>671
                     /standard_name="V_region"
                     /product="immunoglobulin lambda-chain"
                     /gene="IGLV"
                     /codon_start=1
                     /citation=[1]
                     /note="subgroup IV"
     iDNA            672..>836
     misc_recomb     674..680
                     /standard_name="heptamer recombination signal"
                     /citation=[1]
                     /note="putative"
     misc_recomb     704..712
                     /standard_name="nonamer recombination signal"
                     /citation=[1]
                     /note="putative"
BASE COUNT      198 a    243 c    202 g    193 t
ORIGIN      
        1 caaatgtttt agggaatgga gaacagattt gcatccactg ctcaccagag ccacctaacg
       61 acgacacaag aataaaggaa gtagatttgc atgaagagac ttcccttcct atgataagag
      121 aggcctggag gttcctcctt agctgtgggc tcagaagcag agttctgggg tgtctccacc
      181 atggcctgga cccctctctg gctcactctc ctcactcttt gcataggtgc tgcctcccag
      241 ggctcaaccc catattatca tgctagctgt gccaacctgg ccctgagctt cggctcaaca
      301 cagggagtag tgtagggtgt gggactctag gcgtgaaacc cttatcctca cctcttctgt
      361 cctcttttgc aggttctgtg gtttcttctg agctgactca ggaccctgct gtgtctgtgg
      421 ccttgggaca gacagtcagg atcacatgcc aaggagacag cctcagaagc tattatgcaa
      481 gctggtacca gcagaagcca ggacaggccc ctgtacttgt catctatggt aaaaacaacc
      541 ggccctcagg gatcccagac cgattctctg gctccagctc aggaaacaca gcttccttga
      601 ccatcactgg ggctcaggcg gaagatgagg ctgactatta ctgtaactcc cgggacagca
      661 gtggtaacca tctcacagtg acacagacag atggggaagt gagacagaaa ccccttcact
      721 atctgtgtca tcctctctct ccagccccag caggactgtg aacaaagcca taaacagggc
      781 tggcccagtt cacctgcatc tgagacctcc aggctgcctt tccctccatt cctcca
//