From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Sheep MHC class II (OVAR-DQB1) mRNA, complete cds.
Date: 21 Jan 93 05:50:01 GMT
Distribution: bionet
Checksum: 24577 4

LOCUS       SHPMHCIIDQ   1401 bp ss-mRNA            MAM       20-JAN-1993
DEFINITION  Sheep MHC class II (OVAR-DQB1) mRNA, complete cds.
ACCESSION   L08792
KEYWORDS    cell surface glycoprotein; class II gene;
            integral membrane protein.
SOURCE      Ovis aries (strain Merino) (library: lambda gt10) adult mesenteric
            lymph node cDNA to mRNA.
  ORGANISM  Ovis aries
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE   1  (bases 1 to 1401)
  AUTHORS   Fabb,S.A., Gogolin-Ewens,K.J., Smole,C., Maddox,J.F. and
            Brandon,M.R.
  TITLE     Isolation, characterisation and evolution of ovine MHC class II DRB
            and DQB genes
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     87..182
                     /gene="OVAR-DQB1"
                     /codon_start=1
     mat_peptide     183..866
                     /product="major histocompatibility complex class II"
                     /gene="OVAR-DQB1"
                     /codon_start=1
     3'UTR           870..1401
                     /gene="OVAR-DQB1"
     polyA_signal    1382..1387
                     /gene="OVAR-DQB1"
     CDS             87..869
                     /gene="OVAR-DQB1"
                     /product="major histocompatibility complex class II"
                     /codon_start=1
                     /translation="MSGMVALRIPRGLWTAAVMVTLAVLSTPGAEGRDSPQDFVHQFK
                     GLCYFTNGTERVRLVTRYIYNREEYARFDSDWGEYRAVTLGRRQAEYWNSQKDITERV
                     RAEVDTVCRHNYQAELITSLQRRVEPTVTISPTRTEALNHHNLLVCSVTDFYPGRIKV
                     RWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCRVEHPSLQSPIMVE
                     WRAQSESAQSKMLSGVGGFVLGLIFLGLGLIIRHRSQKGLVR"
BASE COUNT      286 a    395 c    391 g    329 t
ORIGIN      
        1 gaagcttgca tgcctgcagg tcgactctag aggatccccg ggtacatggg tgttgactac
       61 cattacttct tgctttgttc tctattatgt ctgggatggt ggctctgcgg atccccagag
      121 gcctttggac ggcagctgtg atggtgaccc tggcggtgct gagcacccca ggggctgagg
      181 gcagagactc gccacaggat ttcgtgcacc agtttaaggg cctgtgttac ttcaccaacg
      241 ggacggagcg ggtgcggctc gtgaccagat acatctacaa ccgggaggag tacgcgcgct
      301 tcgacagcga ctggggcgag taccgggcgg tgacgctggg gcggcggcaa gccgagtact
      361 ggaacagcca gaaggacatc acggagcggg tgcgggccga ggtggacacg gtgtgcagac
      421 acaactacca ggcagagctc atcacctcct tgcagcggcg agtggaacct acagtgacca
      481 tctccccaac caggactgag gctctaaacc accacaacct gctggtctgc tcggtgacag
      541 atttctatcc aggccggatc aaggttcggt ggttccggaa tgaccaggag gagacagccg
      601 gagttgtgtc cacacctctt attaggaacg gggactggac cttccagatc ctcgtgatgc
      661 tggagatgac cccccagcga ggagatgtgt acacctgccg cgtggagcac cccagcctcc
      721 agagccccat catggtggag tggcgggcac agtctgaatc tgcccagagc aagatgctga
      781 gtggtgttgg gggcttcgtg ctggggctga tcttcctcgg gctgggcctc attatccgtc
      841 acaggagcca gaaggggctt gtgcgctgac tcccgaggat actttgatgg agattggact
      901 tcgctcttct gtaatagctg cgtgtcttgc cagaattccc agctgcctgt ctctctgttc
      961 ctctgagatc agatcctata gtgactctga tacagtcact tcctgtgacc acccgcccaa
     1021 cggggatctg gctgtaacga tgctgcttcc tgcaccttcc tgtgtgctgc caaccgcatc
     1081 tactcagacc ctgagaattg tttctgttcc cattttcatt cccatgttca gcctgtcctc
     1141 ctctgagatc agagtctttc ttagattaac tctgacacag tcaccaggtc accccttgtg
     1201 acccctgccc taaggatttg gctgcgatgc tgcttcctgc actggaccct ggagcttctg
     1261 cctgtgcact gccaacagaa tctactcaga ccccaaggga tttctctgtt tccattctcc
     1321 ctctgcagat cgttcaaggg aagcacattg agaccattac ctggttacag agtacatcat
     1381 aattaaacat gaatataaat t
//