From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat S6 protein kinase (Rsk-1) mRNA, complete cds.
Date: 19 Aug 92 10:03:47 GMT
Distribution: bionet
Checksum: 00298     6

LOCUS       RATRSK1X     3131 bp ss-mRNA            ROD       19-AUG-1992
DEFINITION  Rat S6 protein kinase (Rsk-1) mRNA, complete cds.
ACCESSION   M99169
KEYWORDS    S6 protein kinase; Ser/Thr kinase; cytoplasmic protein;
            ribosomal protein kinase.
SOURCE      Rattus norvegicus (library: lambda gt11) cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3131)
  AUTHORS   Grove,J.R., Price,D.J., Banerjee,P., Balasubramanyam,A., Ahmad,M.F.
            and Avruch,J.
  TITLE     Regulation of an epitope-tagged recombinant Rsk-1 S6 kinase by
            phorbol ester and erk/MAP kinase
  JOURNAL   Unpublished (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             142..2349
                     /product="S6 protein kinase"
                     /gene="Rsk-1"
                     /codon_start=1
                     /translation="MPLAQLKEPWPLMELVPLDPENGQASGEEAGLQPSKDEGILKEI
                     SITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLK
                     VRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFT
                     EEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKK
                     AYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK
                     AKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREI
                     KPPFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDSK
                     PRATQAPLHSVVQQLHGKNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVID
                     KSKRDPSEEIEILLRYGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFFS
                     EREASFVLYTISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRA
                     ENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEE
                     ILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLP
                     QSQLSHQDLQLVKGGMAATYSALSSSKPTPQLKPIESSILAQRRVRKLPSTTLS"
BASE COUNT      732 a    891 c    874 g    634 t
ORIGIN
        1 cggcgcggcg gacggcccag ccagagcgcg aggggctggg gggcgtgcgg gggtatcggt
       61 gcagcagcaa ggaccccggg gcccagaggc ggcacagccc ggggccgccc ggaggagcgc
      121 gggcggtccg gcggcggcgc gatgccgctc gcccagctca aggaaccctg gccgctcatg
      181 gagctggtgc cgctggaccc ggagaatgga caggcttcag gggaagaagc tggacttcag
      241 ccatccaagg atgagggcat cctcaaggag atctctatca cacaccacgt caaggcaggc
      301 tctgagaagg ctgatccatc ccattttgag ctcctcaagg ttctgggcca aggatccttt
      361 ggcaaagtct tcctggtacg caaggtcacc cggcctgaca atgggcactt gtatgccatg
      421 aaagtattaa agaaggccac gctgaaagtg cgtgaccgtg ttcggaccaa gatggagaga
      481 gacatcctag ctgacgtgaa ccaccccttc gtagtgaaac tgcactatgc cttccagacc
      541 gagggcaagc tctatcttat tctggacttt ctgcgtggtg gagacctgtt cacacgactc
      601 tcaaaggagg ttatgtttac agaggaggat gtgaagtttt acctggctga gctggcactg
      661 ggcctggacc acctgcacag cttgggcatc atttacagag acctcaagcc tgagaatatc
      721 cttttggatg aggagggcca catcaaactc actgactttg gcctgagcaa ggaggccatt
      781 gaccacgaaa agaaggccta ttccttctgc gggaccgtgg agtacatggc gcccgaggtt
      841 gtcaaccgcc agggccacac ccacagtgca gattggtggt cctatggggt gttgatgttt
      901 gagatgctga cgggctccct gcccttccag gggaaggacc ggaaggagac catgaccttg
      961 attttgaagg caaagctagg catgccccag tttctgagca cggaagccca gagcctcctg
     1021 cgggccctgt tcaagaggaa tcctgccaac cggcttggct caggccccga tggggctgag
     1081 gaaattaaga gacatatctt ctactctacc attgactgga ataagctcta ccgccgtgag
     1141 atcaagccac ctttcaagcc cgctgtggcc cagccggatg acaccttcta ctttgatacc
     1201 gagttcacgt cacgcacacc cagggattcg ccgggcatcc cccccagtgc tggtgcccat
     1261 cagctcttcc gtggcttcag cttcgtggcc accggtctga tggaggatga cagcaagcct
     1321 cgggccaccc aggctccgct gcactcggtg gtacagcaac tccacgggaa gaacttggtt
     1381 ttcagcgatg gctacatagt aaaggagacg atcggcgtgg gctcctactc tgtgtgtaag
     1441 cgctgtgtcc acaaggccac caacatggag tacgcagtca aagtaatcga caaaagcaaa
     1501 agagatccct ccgaagagat cgagattctt ctgcggtatg gacagcaccc caacatcatc
     1561 accctgaaag atgtgtatga cgacagtaag cacgtatacc tggtgacaga gctgatgagg
     1621 ggcggggagc tgctggataa gatcctacgg cagaaattct tctcagagcg ggaggccagc
     1681 ttcgtcctgt acaccatcag caagactgtg gaatacttgc actcccaagg ggtcgtccac
     1741 agggacctca aacccagtaa catcctgtat gtggatgagt ctgggaaccc cgaatgccta
     1801 cgaatatgcg actttggctt tgccaagcag ctacgggctg agaacgggct tctcatgaca
     1861 ccttgctaca cagccaactt tgtggcacct gaggtgctga agcgtcaggg ctacgatgaa
     1921 ggctgtgaca tatggagcct gggcgttctg ctgtacacga tgctggcagg atacactcca
     1981 tttgccaatg ggcccagtga taccccagag gagatcctca cccggatcag cagtgggaag
     2041 ttcaccctca gtgggggaaa ctggaacacg gtttcagaga cagccaagga cttagtatct
     2101 aagatgctgc atgtggaccc ccaccagcgc ctcacagcca aacaggttct gcagcacccg
     2161 tggatcaccc agaaagacaa gctcccccag agccagttgt cccaccaaga cctgcagctt
     2221 gtgaaggggg gcatggcagc tacatattct gcactcagta gctccaaacc caccccccag
     2281 ctcaagccaa tcgagtcgtc catcctggcc cagcggcggg tgaggaagct gccatccacc
     2341 accctgtgaa cgacagtgcg agcaaactcc tctgaggcag agtccttcca gagggagcaa
     2401 gcctgagtca cagaccaagt ggaatggagt cctaaaggaa gcaactagcc cagctcaccc
     2461 gtgcgggtgt gaagtgcctt cctccccagg acgggctctt ctgggctcag gctccattgt
     2521 gtgaaatcca ctcactgtac aaactatttt taagaaagga aaaagaaaaa atgacatcat
     2581 ttaccatgga tttttttttt acaagatcca tttggctttt tggccattgc agtcccagga
     2641 ggaacaccca gtcccatgtg tggccaagac tcccgtgata gctttgggac tccgcccctc
     2701 tgttggtcaa ggagccatct gcacccgcct ccgagcacgt tcggcgttgc ctctcagagt
     2761 tgtcgactgg ctcctcagca gaacttggtg tccccagcca tctctttttc cattctgttc
     2821 tggggttctc gaaccacttt ctgctaagag cccgggactc caccctgtgc agctcttggc
     2881 tcaggcacca gcatccacag cgccccatgc gcagttgggc ccctgcagtc agaacgggca
     2941 gccccgtgga gaggagacgg agagcacttt ttgggagact tcctgttctg ccactggaca
     3001 gagttcacag gagaccaggg aggtagtcca cgggggatga gggctttttc cctttcctcc
     3061 tcagctggta actcagggtt catctgtcca aggcctttct aataaaccta cagtccagtc
     3121 aaaaaaaaaa a
//