From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens titin gene (subclone hum278+279)
Date: 24 Jul 92 10:07:38 GMT
Distribution: bionet
Checksum: 26510     4

LOCUS       HUMTITIN27   1593 bp ds-DNA             PRI       24-JUL-1992
DEFINITION  H.sapiens titin gene (subclone hum278+279)
ACCESSION   X64699
KEYWORDS    fibronectin type-III repeat; immunoglobulin-C2; myosin-binding;
            titin gene.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1593)
  AUTHORS   Labeit,S., Gautel,M., Lakey,A. and Trinick,J.
  TITLE     Towards a molecular understanding of titin
  JOURNAL   EMBO J. 11, 1711-1716 (1992)
  STANDARD  full automatic
COMMENT     *source: clone_library=PCR of genomic DNA; *source: chromosome=2;
            *source: sub_clone=hum(278+279);
            Related sequence: X17329
            From EMBL    entry HSTITIN27;  dated 12-MAY-1992.
FEATURES             Location/Qualifiers
     CDS             <1..>1593
                     /product="titin"
                     /codon_start=1
                     /translation="AYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQ
                     GYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP
                     GPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDA
                     AIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTE
                     ITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCS
                     YYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGS
                     KIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA
                     VPIVAKDLVIEPDVKPAFSSYSVQVGQDLKMEVPIFGRPKPTITWTKDGLPLKQTTRI
                     NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDD
                     VSAESITLSWNPPLYTGGCQITN"
BASE COUNT      533 a    306 c    342 g    412 t
ORIGIN
        1 gcttaccaaa aggcttgtga tcctatttat aaaccaggac ccccaaacaa ccccaaagtc
       61 atagacataa ccagatcttc agtattcctt tcttggagca aaccaatata tgatggtggc
      121 tgtgaaattc aaggatacat tgttgaaaaa tgtgatgtga gtgttggtga atggacaatg
      181 tgcactccac caacaggaat taataaaaca aacatagaag tagagaagct gttggaaaag
      241 catgaataca acttccgtat ctgtgctatt aataaagctg gagttggaga acatgctgac
      301 gtccctggac ctattatagt tgaagaaaaa ttagaagcac cagacattga tcttgaccta
      361 gaactaagga aaatcataaa tataagggca ggtggctcct taaggttatt tgttcctata
      421 aaaggtcgtc ctacaccaga agttaaatgg ggaaaggtgg atggtgaaat ccgagatgca
      481 gctataattg atgtcactag cagtttcacc tctcttgttc ttgacaatgt caaccgatat
      541 gatagtggaa aatatacgct tacattagaa aacagcagtg gaacaaagtc tgcctttgtt
      601 actgtgagag ttctggacac gccaagtcca cctgttaacc tgaaagtcac agaaatcacc
      661 aaagactcag tatcaattac atgggaacct cctttgttgg atgggggatc caaaataaaa
      721 aattacattg ttgagaaacg tgaagccaca agaaaatcat atgctgctgt tgtaactaac
      781 tgccataaga attcttggaa aatcgatcag ctccaagaag gttgcagtta ttactttaga
      841 gtcacagctg agaatgagta tggtattggc cttcctgccc agactgctga tccaattaag
      901 gttgcagaag tgccacaacc tcctggaaaa ataactgtgg atgatgtcac cagaaacagt
      961 gtctctctga gttggacaaa acctgaacat gatggtggca gtaaaatcat tcagtatatt
     1021 gtggaaatgc aagctaaaca cagtgagaaa tggtcagagt gtgctcgagt aaagtctctt
     1081 caggcagtaa ttaccaacct aactcaaggg gaagaatatc tttttagagt tgttgctgta
     1141 aatgaaaagg ggagaagtga tcctcggtcc cttgcagttc caatagttgc caaagatctg
     1201 gtaattgagc cagatgtaaa acctgcattc agtagttaca gtgtacaggt tggccaagat
     1261 ttgaaaatgg aagtgccaat ttttggacgt cctaagccaa ccattacctg gactaaagat
     1321 ggtctcccac tgaagcagac cacaagaatc aatgttaccg attcactgga tctcaccaca
     1381 ctcagtatta aagaaactca taaggatgat ggtggacaat atggaatcac agttgccaat
     1441 gttgttggtc agaagacagc atccatcgaa attgtaactc tagataaacc tgatcctcca
     1501 aaaggacctg ttaaatttga tgacgtcagt gctgaaagta ttacattatc ttggaaccct
     1561 ccattatata cagggggctg ccaaatcacc aac
//