From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Paracoccus denitrificans NADH dehydrogenase (URF4), (NQO8), (NQO9),
Date: 5 Sep 92 10:02:10 GMT
Distribution: bionet
Checksum: 02068    23

LOCUS       PDENQOURF   10425 bp ds-DNA             BCT       05-SEP-1992
DEFINITION  Paracoccus denitrificans NADH dehydrogenase (URF4), (NQO8), (NQO9),
            (URF5), (URF6), (NQO10), (NQO11), (NQO12), (NQO13), and (NQO14)
            genes, complete cds, biotin [acetyl-CoA carboxyl] ligase (birA)
            gene, complete cds.
ACCESSION   L02354
KEYWORDS    Complex I dehydrogenase; NADH dehydrogenase (ubiquinone);
            NQO10 gene; NQO11 gene; NQO12 gene; NQO13 gene; NQO14 gene;
            NQO8 gene; NQO9 gene; Type I dehydrogenase; URF4 gene; URF5 gene;
            URF6 gene; biotin [acetyl-CoA carboxylase] ligase; birA gene;
            flavoprotein; ubiquinone reductase.
SOURCE      Paracoccus denitrificans DNA.
  ORGANISM  Paracoccus denitrificans
            Prokaryotae; Gracilicutes; Scotobacteria; Neisseriaceae.
REFERENCE   1  (bases 1 to 10425)
  AUTHORS   Yagi,T., Xu,X. and Matsuno-Yagi,A.
  TITLE     Complete DNA Sequence of the Gene Cluster of the Energy-Transducing
            NADH-Quinone Oxidoreductase of Paracoccus denitrificans:
            Characterization of the seven structural gene products
  JOURNAL   Unpublished (1993)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     CDS             57..824
                     /number=1
                     /function="unknown"
                     /EC_number="1.6.5.3"
                     /product="NADH dehydrogenase"
                     /gene="URF4"
                     /note="putative"
                     /codon_start=1
                     /translation="MRPRLALLSGIGALALLAGCAETKDARPRPKPAELGVAVLQSDA
                     GAPDKKTLTRGRISTKSGEILILEPDGSVSEMALDSPEGRDAFAVTEAELMALNANLE
                     LDLSGLPNMAPVRKREPTAQEKALAAFSARSRPLRLNLPVSFEADPQDFQGAQVAALA
                     SSRKGADSLVEVTANLRGGVDADTAFAYATCALASWADAKGASYARHIRTLRDKRNGK
                     MVVGSVFTLSEKKPMGLTVMTTKQTLQECKARGIPAA"
                     /citation=[1]
     CDS             843..1880
                     /number=2
                     /EC_number="1.6.5.3"
                     /note="ND1 homologue of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO8"
                     /note="putative"
                     /codon_start=1
                     /translation="MAEFWASPYGFALSMLLQGLAVIAFVMGSLIFMVYGDRKIWAAV
                     QMRRGPNVVGPWGLLQTFADALKYIVKEIVIPAGADKFVYFLAPFLSMMLALFAFVVI
                     PFDEGWVMANINVGILFIFAASSLEVYGVIMGGWASNSKYPFLASLRSAAQMISYEVS
                     LGLIIIGIIISTGSMNLTAIVEAHGGDYGLLNWYWLPHLPMVVLFFVSALAECNRPPF
                     DLVEAESELVAGFMTEYSSTPYLLFMAGEYIAMYLMCALLSLLFFGGWLSPVPFIADG
                     WWWMVIKMWFWFYMFAMVKAIVPRYRYDQLMRIGWKVFLPLSLGWVVLVAILARYEIL
                     GGFWARFAVGG"
                     /citation=[1]
     CDS             2066..2557
                     /number=3
                     /EC_number="1.6.5.3"
                     /note="20K subunit of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO9"
                     /note="putative"
                     /codon_start=1
                     /translation="MAFDFARATKYFLMWDFIKGFGLGMRYFVSPKPTLNYPHEKGPL
                     SPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIDAERREDGSRRTTRYDIDMTK
                     CIYCGFCQEACPVDAIVEGPNFEYATETREELFYDKQKLLANGERWEAEIARNLQLDA
                     PYR"
                     /citation=[1]
     CDS             2554..2946
                     /number=4
                     /EC_number="1.6.5.3"
                     /note="URF5 gene product of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="URF5"
                     /note="putative"
                     /codon_start=1
                     /translation="MTADAAYQRGRALAEHLNPGMEVALRDRYGRWLPDAVAETVVGH
                     GMGEVYAREGLDLKTRLLVTVGALAAMGGQTRPQLKVNVASALRAGASAREICEAIFQ
                     MHLYGGMPAAINALNAAIEVFEAEGTSP"
                     /citation=[1]
     CDS             2943..3347
                     /number=5
                     /EC_number="1.6.5.3"
                     /note="URF6 gene product of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="URF6"
                     /note="putative"
                     /codon_start=1
                     /translation="MTDAFQKLFQQMLQSGQEMARAFNPALEHFDMRAMEKLVPTIPA
                     DMLEMWFGKTFNREGLDAKTRLLLTIGAITVQGALAEPQLRMTVRQALAAGATKREIA
                     ETIFQMSMFGGLPAMQKALEIAQSVYAEEDEE"
                     /citation=[1]
     CDS             3344..3946
                     /number=6
                     /EC_number="1.6.5.3"
                     /note="ND6 homologue of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO10"
                     /note="putative"
                     /codon_start=1
                     /translation="MMTFAFYLFAISACVAGFMVVIGRNPVHSVLWLILAFLSAAGLF
                     VLQGAEFVAMLLVVVYVGAVAVLFLFVVMMLDVDFAELKGELARYLPLALVIGVVLLA
                     QLGIAFSGWTPSDQAESLRAAPVDAAVENTLGLGLVLYDRYVLMFQLAGLVLLVAMIG
                     AIVLTMRHRKDVKRQNVLEQMWRDPAKTMELKDVKPGQGL"
                     /citation=[1]
     CDS             4046..4351
                     /number=7
                     /EC_number="1.6.5.3"
                     /note="ND4l homologue of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO11"
                     /note="putative"
                     /codon_start=1
                     /translation="MIGLTHYLVVGAILFVTGIFGIFVNRKNVIVILMSIELMLLAVN
                     INFVAFSTHLGDLAGQVFTMFVLTVAAAEAAIGLAILVVFFRNRGTIAVEDVNVMKG"
                     /citation=[1]
     CDS             4358..6469
                     /number=8
                     /EC_number="1.6.5.3"
                     /note="ND5 homologue of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO12"
                     /note="putative"
                     /codon_start=1
                     /translation="MEKFVLFAPLIASLIAGLGWRAIGEKAAQYLTTGVLFLSCLISW
                     YLFLSFDGVPRHIPVLDWVVTGDFHAEWAIRLDRLTAIMLIVVTTVSALVHMYSLGYM
                     AHDDNWTHDEHYKARFFAYLSFFTFAMLMLVTADNLLQMFFGWEGVGVASYLLIGFYY
                     KKASANAAAMKAFIVNRVGDFGFLLGIFGIYWLTGSVQFDEIFRQVPQLAQTEIDFLW
                     RDWNAANLLGFLLFVGAMGKSAQLLLHTWLPDAMEGPTPVSALIHAATMVTAGVFLVC
                     RMSPLYEFAPDAKNFIVIIGATTAFFAATVGLVQNDIKRVIAYSTCSQLGYMFVAAGV
                     GVYSAAMFHLLTHAFFKAMLFLGAGSVIHAMHHEQDMRNYGGLRKKIPLTFWAMMIGT
                     FAITGVGIPLTHLGFAGFLSKDAIIESAYAGSGYAFWLLVIAACFTSFYSWRLIFLTF
                     YGKPRGDHHAHDHAHESPPVMTIPLGVLAIGAVFAGMVWYGPFFGDHHKVTEYFHIAG
                     AHHEAAEGEEAEHATAEAPVEHAVADTATAEGEAAAEAEHAEIAAPVGGAIYMHPDNH
                     IMDEAHHAPAWVKVSPFVAMVLGLITAWTFYIANPSLPRRLAAHEPALYRFLLNKWYF
                     DEIYEFIFVRPAKWLGRVLWKGGDGAVIDGTINGVAMGLIPRLTRAAVRVQSGYLFHY
                     AFAMVLGIVGLLIWVMMRGAH"
                     /citation=[1]
     CDS             6471..8012
                     /number=9
                     /EC_number="1.6.5.3"
                     /note="ND4 homologue of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO13"
                     /note="putative"
                     /codon_start=1
                     /translation="MTNLLSIITFLPIVAAIIMALFLRGQDEAAARNAKWLALLTTTA
                     TFVISLFVLFRFDPANTGFQFVEDHAWIMGVCYKMGVDGISVLFVLLTTFMMPLTILS
                     TWQVQDKVKEYMIAFLVLEGLMIGVFTALDLVLFYLFFEAGLIPMFLIIGIWGGKDRI
                     YASFKFFLYTFLGSVLMLVAMIAMYRMAGTTDIPTLLTFDFPSENFRLLGMTVVGGMQ
                     MLLFLAFFASFAVKMPMWPVHTWLPDAHVQAPTAGSVLLAAVLLKMGGYGFLRFSLPM
                     FPVASGVAQPYVFWLSAIAIVYTSLVALAQSDMKKVIAYSSVAHMGYVTMGVFAANQI
                     GVDGAIFQMLSHGFISGALFLCVGVIYDRMHTREIDAYGGLVNRMPAYAAVFMFFTMA
                     NVGLPGTSGFVGEFLTLMGVFRVDTWVALVATSGVILSAAYALWLYRRVTLGQLIKES
                     LKSITDMTPRERWVFIPLIAMTLILGVYPRLVTDVTGPAVAALVQDYNQSQPAAPVAT
                     AQASH"
                     /citation=[1]
     CDS             8022..9521
                     /number=10
                     /EC_number="1.6.5.3"
                     /note="ND2 homologue of Paracoccus NDH-1"
                     /product="NADH dehydrogenase"
                     /gene="NQO14"
                     /note="putative"
                     /codon_start=1
                     /translation="MTSLDFSTILPEVVLAGYALAALMAGAYLGKDRLARTLLWVTVA
                     AFLVVAAMVGLGNHVDGAAFHGMFIDDGFSRFAKVVTLVAAAGVLAMSADYMQRRNML
                     RFEFPIIVALAVLGMMFMVSAGDLLTLYMGLELQSLALYVVAAMRRDSVRSSEAGLKY
                     FVLGSLSSGLLLYGASLVYGFAGTTGFEGIISTIEAGHLSLGVLFGLVFMLVGLSFKV
                     SAVPFHMWTPDVYEGSPTPVTAFFATAPKVAAMALIARLVFDAFGHVIGDWSQIVAAL
                     AVMSMFLGSIAGIGQTNIKRLMAYSSIAHMGFALVGLAAGTAIGVQNMLLYMTIYAVM
                     NIGTFAFILSMERDGVPVTDLAALNRFAWTDPVKALAMLVLMFSLAGVPPTLGFFAKF
                     GVLTAAVDAGMGWLAVLGVIASVIGAFYYLRIVYYMYFGGESEGMTSRMGAVQYLALM
                     VPALAMLVGAISMFGVDSAAGRAAETLVGPVAAIEQPAEAAQAEPVQGE"
                     /citation=[1]
     CDS             9550..10272
                     /number=11
                     /product="biotin [acetyl-CoA carboxylase] ligase"
                     /gene="birA"
                     /note="putative"
                     /codon_start=1
                     /translation="MLARTDSTNAEALKLAPGLSGSAWVLAREQFAGRGRRGREWVMP
                     AGNFAGTLVLRPQGGALAAAQLSFVAALALYDALGLACGPAARLAIKWPNDVLLNGGK
                     VAGILLESSGSGPGVQAVAVGIGVNLAGAPDAGAVEPGATPPVSVQGETGHAVDPEEF
                     LDLLAPAFARWQAQLDTYGFAPIRNAWLARAARLGEPIIARTGTAESHGIFEGIDDSG
                     ALILRGPAGRQVIPAAEVFFGG"
                     /citation=[1]
BASE COUNT     1593 a   3345 c   3418 g   2069 t
ORIGIN
        1 tcggcgatgg ccgcggcccg caaggccccg gcgccgttgg cggcggagtg acggggatgc
       61 ggccccgcct tgcccttctg agcggtatcg gcgccctggc cctgctggcc ggctgcgccg
      121 agaccaagga tgcgcgcccg cggcccaagc cggccgaact gggcgtggcg gtgctgcaaa
      181 gtgacgcagg cgcgccggac aagaagacgc tgaccagggg ccggatctcg accaaatccg
      241 gcgagatcct gattctcgaa cccgacggtt cggtcagcga gatggcgctg gacagccccg
      301 agggccgcga cgccttcgcg gtgaccgagg ccgagttgat ggctctgaac gcgaatctgg
      361 agctggacct gtccggcctg ccaaacatgg ccccggtgcg caagcgcgag cccacggcgc
      421 aggaaaaggc gctggctgca ttctcggccc gttcccgccc gttgcggctg aacctgcccg
      481 tgagtttcga ggccgatccc caggatttcc agggcgcgca ggtcgccgcg ctggccagtt
      541 cgcgcaaggg ggcggacagc ctggtggaag ttacggcaaa cctgcgcggc ggggtggacg
      601 ccgacaccgc cttcgcctat gccacatgcg cgctggccag ctgggccgat gcgaaagggg
      661 cgtcctacgc ccggcacatc cgcacgctcc gggacaagcg caacggcaag atggtcgtcg
      721 gttcggtatt cacgctttcc gagaaaaaac cgatgggcct gacggtgatg acaacgaaac
      781 agaccttgca ggaatgcaag gcacgcggca ttcccgcggc gtgatgagag ggacgaaaga
      841 tcatggctga attctgggcc tcgccctacg gtttcgcgct cagcatgctc ttgcagggtc
      901 tggcggtcat cgccttcgtc atgggttcgc tgatcttcat ggtctatggc gaccgcaaga
      961 tctgggcggc ggtgcagatg cgccgcggcc cgaacgtggt cggcccctgg ggcttgttgc
     1021 agaccttcgc cgacgcgctg aaatacatcg tcaaggaaat cgtcattccg gccggcgcgg
     1081 acaagttcgt ctatttcctg gcgcccttcc tgtcgatgat gctggcgctg ttcgcctttg
     1141 tggtcatccc cttcgacgaa ggctgggtga tggcgaacat caacgtgggc atcctgttca
     1201 tctttgccgc ctcctctctc gaggtctacg gcgtcatcat gggcggctgg gcctcgaact
     1261 cgaaatatcc gttcctcgcc tcgttgcggt cggcggcgca gatgatctcc tacgaggtgt
     1321 cgctggggct gatcatcatc gggatcatca tctcgaccgg ctcgatgaac ctgaccgcca
     1381 tcgtcgaggc gcacggcggc gattacgggt tgctgaactg gtattggctg ccgcacctgc
     1441 cgatggtggt gctgttcttc gtctcggcgc tcgccgagtg caaccgccca cccttcgacc
     1501 tggtcgaggc cgagtccgaa ctggtcgcgg gcttcatgac cgaatattcg tccacgccct
     1561 acctgctgtt catggcgggc gaatatatcg ccatgtatct gatgtgcgcg ctcctgtcgc
     1621 tgctgttctt cggcggctgg ctgtcgccgg tgccgttcat cgccgacggc tggtggtgga
     1681 tggtcatcaa gatgtggttc tggttctaca tgttcgccat ggtcaaggcg atcgtgccgc
     1741 gctaccgcta cgaccagctg atgcgcatcg gctggaaggt gttcctgccc ctgtcgctgg
     1801 gctgggtggt gctggtggcg atcctggccc gctacgaaat cctgggcggc ttctgggccc
     1861 gctttgcggt cggaggataa gccatgtatt ccaacaagct agccgaggca tttgccaaag
     1921 ccagtgagac cgacaaggtg gagctggcgc atttcctcgc caacaatctg gacagtgcgg
     1981 aacaagcgca ggacggcgcc cgcattcggg attatgtcgc cgcgttcgac cgtttcgcgg
     2041 cccccaggga aggggagcgt ttctgatggc cttcgatttc gcccgtgcga ccaaatattt
     2101 cctgatgtgg gatttcatca agggcttcgg cctggggatg cgctatttcg tgtcgcccaa
     2161 gccgacgctg aactacccgc atgaaaaggg cccgctgtcg ccgcgcttcc ggggcgaaca
     2221 cgcactgcgc cgctatccca acggcgagga acgctgcatc gcctgcaagc tgtgcgaggc
     2281 ggtctgcccg gcacaggcca tcaccatcga cgccgaacgc cgcgaggacg gctcgcgccg
     2341 gaccacgcgc tacgacatcg acatgacgaa atgcatctat tgcggcttct gccaggaagc
     2401 ctgcccggtc gatgccatcg tcgagggtcc gaacttcgaa tatgcgaccg aaacccgcga
     2461 ggagctgttc tacgacaagc agaagctgct tgcgaacggc gaacgctggg aggccgagat
     2521 cgcccgcaac ctgcaactgg atgcgcccta cagatgaccg ctgacgccgc atatcagcgc
     2581 ggccgcgccc tggccgagca tctcaatccg gggatggagg tggccctgcg cgaccgctat
     2641 ggccgctggc tgcccgatgc ggtggccgaa acggtcgtgg gtcacgggat gggcgaggtc
     2701 tatgcgcgcg aggggctgga tctgaagacc cggctgctgg tcaccgtcgg cgcattggcg
     2761 gcgatgggcg ggcagacccg gccgcagctc aaggtgaacg tggcctcggc cctgcgcgcg
     2821 ggcgcaagcg cgcgggaaat ctgcgaggcg atcttccaga tgcacctcta tggcgggatg
     2881 ccggcggcga tcaacgcgtt gaacgccgcc atcgaggttt tcgaagcgga aggaacaagt
     2941 ccatgaccga tgccttccag aagctgttcc agcagatgct gcaatccggc caggagatgg
     3001 cgcgcgcctt caacccggcg ctcgagcatt tcgacatgcg cgccatggaa aagctggtgc
     3061 cgaccattcc tgccgacatg ctggaaatgt ggttcggcaa gaccttcaac cgcgaggggc
     3121 tggacgccaa gacgcgcctg cttctcacca tcggcgcgat caccgttcag ggcgcgctgg
     3181 ccgagccgca actgcgcatg accgtccgtc aggcgctggc ggccggcgcc accaaacgcg
     3241 agatcgccga gacgatcttt cagatgagca tgttcggcgg gctgcccgcg atgcagaagg
     3301 cgctggaaat cgcccagagc gtctatgccg aggaggacga ggaatgatga ccttcgcttt
     3361 ctacctgttc gcgatcagcg cctgcgtcgc cgggttcatg gtcgtgatcg gccgcaaccc
     3421 ggtgcattcg gtgttgtggc tgatcctggc cttcctgtcc gcggcggggc tgttcgtgct
     3481 gcaaggcgcg gagttcgtcg ccatgctgct ggtcgtggtc tatgtcggcg ccgtggcggt
     3541 gctgttcctg ttcgtcgtca tgatgctgga cgtggatttc gccgagctga agggcgaact
     3601 ggcgcgctac ctgccgctgg cgctggtgat tggcgtcgtg ctgctggcgc aactgggcat
     3661 cgccttctcg ggctggacgc cctcggacca ggccgaaagc ctgcgcgccg ctccggtgga
     3721 tgcggcggtc gagaacaccc tgggcctcgg cctcgtgctt tacgaccgct atgtgctgat
     3781 gttccagctt gccggcctgg tgctgctggt ggcgatgatc ggggcgatcg tgctgaccat
     3841 gcgccaccgc aaggacgtca agcgccagaa cgtgctggaa cagatgtggc gcgacccggc
     3901 caagacgatg gaattgaagg acgtgaagcc ggggcagggg ctttgaacgc ggcaggctgg
     3961 accgcgatag ccatcgggat cgtcacggcg gtcctagtag caaacggata tttcaacggg
     4021 tgaacgaccc ggagggacca ggacgatgat cggattgact cattatcttg ttgtgggggc
     4081 gatattgttc gtcaccggca ttttcgggat cttcgtgaac cgaaagaacg tcatcgtcat
     4141 cctgatgtcg atcgaactga tgctgctggc ggtgaacatc aacttcgtcg ccttctcgac
     4201 ccatctgggc gatctggccg ggcaggtctt caccatgttc gtgctgaccg tcgccgccgc
     4261 cgaggccgcc atcggcctgg cgatcctggt ggtcttcttc cgcaaccgcg gcaccatcgc
     4321 ggtggaagac gtcaacgtga tgaagggata agcggccatg gaaaaattcg tcctctttgc
     4381 gccgctcatc gcgtcgctga tcgccgggct gggctggcgg gcgatcggcg agaaggcagc
     4441 gcaatacctg accacgggcg tgctgttcct cagctgcctg atcagctggt acctgtttct
     4501 gtccttcgac ggcgtgccgc ggcatatccc ggtgctcgac tgggtcgtga ccggcgattt
     4561 ccatgccgaa tgggcgatcc ggctggaccg gctgaccgcg atcatgctga tcgtcgtgac
     4621 caccgtttcg gcgctcgtgc acatgtattc gctgggctac atggcccatg acgacaactg
     4681 gacgcatgac gagcactaca aggcccgctt cttcgcctat ctctcgttct tcaccttcgc
     4741 catgctgatg ctggtgacgg cggacaacct gttgcagatg ttcttcggct gggagggcgt
     4801 gggcgtcgcc tcctacctac tgatcggatt ctactacaag aaggccagcg ccaatgccgc
     4861 ggcgatgaag gcgttcatcg tcaaccgggt cggcgacttc ggcttcctgc tgggtatctt
     4921 cggcatctac tggctgaccg gctcggtcca gttcgacgag atcttccgcc aggtgccgca
     4981 gctcgcgcag accgagatcg atttcctgtg gcgcgactgg aacgccgcga acctgctggg
     5041 tttcctgctg ttcgtcggcg ccatgggcaa gtcggcgcag ctcttgctgc acacctggct
     5101 gccggacgcg atggaaggcc cgaccccggt ttcggcgctg atccatgccg cgaccatggt
     5161 gacggccggc gtgttcctgg tctgccgcat gtcgccgctt tacgaattcg cgccggatgc
     5221 caagaacttc atcgtcatca tcggcgccac caccgccttc ttcgccgcga ccgtcggcct
     5281 ggtgcagaac gacatcaagc gcgtcatcgc ctattcgacc tgttcgcagt tgggctacat
     5341 gttcgtggcg gcgggtgtcg gcgtctattc ggcggccatg ttccacctgc tgacgcacgc
     5401 tttcttcaag gccatgctgt tcctgggcgc cggctcggtg atccatgcca tgcaccatga
     5461 acaggacatg cggaactatg gcgggctgcg gaagaagatc ccgctgacct tctgggcgat
     5521 gatgatcggc accttcgcca tcaccggcgt cggcattccg ctgacccacc tgggctttgc
     5581 cggtttcctg tccaaggacg cgatcatcga aagcgcctat gcgggcagcg gctatgcctt
     5641 ctggctgctg gtcatcgcgg cctgtttcac cagcttctac agctggcggc tgatcttcct
     5701 gaccttctac ggcaagccgc gcggcgacca tcacgcccat gatcatgcgc atgaaagccc
     5761 gccggtgatg acgatcccgc tgggcgtgct ggccatcggc gcggtctttg ccggcatggt
     5821 ctggtatggt cccttcttcg gcgaccatca caaggtcacg gaatatttcc acatcgccgg
     5881 cgcgcatcac gaagcggccg agggcgaaga agcagagcac gcgaccgccg aggctccggt
     5941 ggagcacgcc gtcgccgata ccgcgaccgc cgagggcgaa gcggccgccg aggccgaaca
     6001 tgccgagatc gccgcgccgg tcggcggtgc gatctacatg catcccgaca accacatcat
     6061 ggacgaggcg caccatgcgc cggcctgggt gaaggtctcg cccttcgtcg ccatggtgct
     6121 ggggctgatc accgcctgga cattctacat cgccaacccg tcgctgccgc ggcggctggc
     6181 ggcgcacgag ccggcgctgt atcggttcct gctcaacaaa tggtatttcg acgagatcta
     6241 cgagttcatc ttcgtccgcc cggcgaaatg gcttggccgc gtgctgtgga agggcggcga
     6301 cggcgccgtc atcgacggca ccatcaacgg ggtggccatg ggcttgatcc cgcggctgac
     6361 ccgcgcggcg gtccgggtgc aatcgggcta tctgttccac tacgccttcg cgatggttct
     6421 gggcatcgtg ggcttgctga tctgggtgat gatgcggggc gcgcactgac atgacgaacc
     6481 ttctttccat catcaccttc ctgccgatcg tcgccgccat catcatggcg ctgttcctgc
     6541 gcggccagga cgaggccgcg gcgcgcaacg ccaaatggct ggcgctgctg accaccacgg
     6601 cgaccttcgt gatctcgctt ttcgtgctgt tccgcttcga cccggcgaac accggcttcc
     6661 agttcgtcga ggatcacgcc tggatcatgg gcgtctgcta caagatgggc gtggacggca
     6721 tctcggtgct gttcgtgctg ctgaccacct tcatgatgcc gctgaccatc ctttcgacct
     6781 ggcaggtcca ggacaaggtc aaggaataca tgatcgcctt cctggtgctg gaagggctga
     6841 tgatcggcgt cttcaccgcg ctcgatctgg tgctgttcta cctgttcttc gaggcggggc
     6901 tgatcccgat gttcctgatc atcggcatct ggggcggcaa ggaccgcatc tatgcgtcct
     6961 tcaagttctt cctctacacc ttcctcggct cggtgctgat gctggtggcg atgatcgcca
     7021 tgtatcgcat ggcgggcacc accgacatcc cgacgctgct gaccttcgac ttcccgtccg
     7081 agaacttccg cctcttgggc atgaccgtgg tcggcggcat gcagatgctg ctgttcctgg
     7141 ccttctttgc cagcttcgcg gtcaagatgc cgatgtggcc ggtccatacc tggctgcccg
     7201 acgcgcacgt ccaggcgccg accgccggct cggtcctgct ggccgcggtg ctgctgaaga
     7261 tgggcggcta cggcttcctg cgcttctcgc tgccgatgtt cccggtcgcc agcggcgtgg
     7321 cccagcccta tgtcttctgg ctgtcggcca tcgccatcgt ctacacttcg ctggtggcgc
     7381 tggcgcagtc ggacatgaag aaggtcatcg cctattcctc ggtcgcccat atgggctacg
     7441 tgaccatggg cgtctttgcc gcgaaccaga tcggcgtcga cggcgcgatc ttccagatgc
     7501 tgtcgcacgg ctttatctcg ggcgcgctgt tcctgtgcgt cggcgtgatc tacgaccgca
     7561 tgcacacgcg cgagatcgac gcctatggcg ggttggtgaa ccggatgccg gcctatgcgg
     7621 cggtgttcat gttcttcacc atggcgaacg tgggcctgcc gggcacctcg ggtttcgtgg
     7681 gcgagttcct gacgctgatg ggggtcttcc gcgtcgatac ctgggtggcg ctggtcgcga
     7741 cctcgggggt gatcctgtcg gcggcctatg cgctctggct gtatcgccgg gtgacgctgg
     7801 gccagctcat caaggaaagc ctcaagtcga tcaccgacat gaccccgcgc gaacgctggg
     7861 tgttcatccc gctgatcgcc atgacgctga tcctgggcgt ctatccgcgg ctcgtcaccg
     7921 acgtgaccgg cccggcggtc gcagcactcg tgcaagacta caaccagagc cagccggcgg
     7981 cacccgtcgc cacggcccaa gccagccact aggggacgga catgacctcg ctcgatttct
     8041 cgaccattct gcccgaggtg gtgctggccg gttacgccct tgccgccctg atggcggggg
     8101 cctatctcgg caaggacagg ctggcccgga cgctgctttg ggtcacggtc gcggccttcc
     8161 tggtcgtcgc ggccatggtg ggcctcggca accatgtcga cggcgccgcc ttccacggca
     8221 tgttcatcga cgacggcttc tcgcgctttg ccaaggtggt gacgctggtc gccgccgccg
     8281 gcgtgctggc gatgagcgcc gattacatgc agcgccgcaa catgctgcgc ttcgagttcc
     8341 cgatcatcgt tgcactggcg gtgctgggca tgatgttcat ggtctcggcc ggcgacctgc
     8401 tgacgctcta catggggctg gagttgcaat cgctggcgct ttacgtcgtc gccgccatgc
     8461 gccgcgactc ggtgcgctcg tccgaggcgg ggttgaaata cttcgtgctg ggatcgcttt
     8521 cctcgggcct gctgctctat ggcgcctcgc tggtctacgg ttttgccggc accaccgggt
     8581 tcgagggcat catctcgacc atcgaggccg gccacctgtc cctgggcgtg ctgttcggcc
     8641 tggtgttcat gctggtgggc ctgtcgttca aggtttcggc cgtgcccttc cacatgtgga
     8701 cgcccgacgt ctacgagggc tcgccgacgc cggtcaccgc cttcttcgcc accgcgccca
     8761 aggtcgcggc catggcgctg atcgcgcggc tggtcttcga cgccttcggc catgtcatcg
     8821 gcgactggag ccagatcgtc gcggcgctgg cggtgatgtc gatgttcctg ggctcgatcg
     8881 ccgggatcgg ccagaccaac atcaagcggc tgatggccta ttcctcgatc gcgcatatgg
     8941 gctttgccct tgtcggcctt gccgccggca ccgccatcgg cgtgcagaac atgctgcttt
     9001 acatgaccat ctatgcggtg atgaacatcg gcaccttcgc cttcatcctg tcgatggagc
     9061 gcgacggcgt gccggtgacc gaccttgccg cgctgaaccg ctttgcctgg accgatccgg
     9121 tcaaggcgct ggcgatgctg gtcctgatgt tcagccttgc aggcgtgccg ccgacgctgg
     9181 gcttctttgc caagttcggc gtgctgacgg cggcggtcga tgccggcatg ggctggctgg
     9241 cggtgctggg cgtgatcgcc tcggtcatcg gcgccttcta ttacctgcgc atcgtctatt
     9301 acatgtattt cggcggcgag tccgagggca tgacctcgcg catgggcgcg gtgcaatacc
     9361 tggcgctgat ggtgccggcg ctggcgatgc tggtgggtgc gatcagcatg ttcggcgtcg
     9421 attccgccgc cggccgcgcc gccgagaccc tggtcggtcc ggtggccgcc atcgagcagc
     9481 ccgccgaagc cgcgcaagcc gagcccgtgc aaggtgagtg acgcctggcc cgagggcgtg
     9541 gcccgccatg tgctggcccg caccgacagc accaatgccg aggcgctgaa gctggcgccc
     9601 ggcctttccg gttctgcctg ggtgctggcc cgcgagcaat tcgcgggccg tggccgtcgc
     9661 gggcgcgaat gggtcatgcc ggccggaaac tttgccggca cgctggttct gcggccccag
     9721 ggaggggcgc tggcggcggc gcaactgtcc ttcgtcgccg cgctggcgct ctacgatgcg
     9781 cttggtctgg cctgcggccc ggccgcgcgg ctggcgatca aatggccgaa cgacgtgctg
     9841 ctgaacggcg gcaaggtggc gggcatcctg ctggaaagct cgggctccgg ccccggcgtg
     9901 caggccgtcg cggtcggcat cggcgtcaac ctggccggcg cgcccgatgc cggcgcggtc
     9961 gagcccggtg ccaccccgcc ggtttccgtg caaggcgaga ctggccacgc cgtcgatccc
    10021 gaggaattcc tggacctgct ggcgccggcc tttgcacgct ggcaggcgca actcgacacc
    10081 tatggcttcg cgccgatccg caatgcctgg ctggcccgcg cggcccggct gggcgagccg
    10141 atcatcgccc gcaccggcac tgccgaaagc cacggcatct tcgagggcat cgacgacagc
    10201 ggcgcgctga tcctgcgcgg cccggcgggg cggcaggtca ttcccgccgc cgaagtcttt
    10261 ttcggaggct aggccatgct gctttgcatc gacaccggca acaccaacac ggtcttttcc
    10321 gtctgggacg gcgagaaatt cgtgggcctc tggcgcatct cgaccgacca ccggcgcacg
    10381 gcggacgagt atttcgtctg gctatccacg ctgatttccc tgcag
//