From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus rattus guanine nucleotide dissociation stimulator for a
Date: 31 Dec 92 01:39:41 GMT
Distribution: bionet
Checksum: 41138 8

LOCUS       RATGNDSA     3665 bp ss-mRNA            ROD       17-DEC-1992
DEFINITION  Rattus rattus guanine nucleotide dissociation stimulator for a
            ras-related GTPase mRNA, complete cds.
ACCESSION   L07925
KEYWORDS    exchange factor; guanine nucleotide dissociation stimulator.
SOURCE      Rattus rattus (library: of Xiao Fan Wang) cDNA to mRNA.
  ORGANISM  Rattus rattus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3665)
  AUTHORS   Albright,C.F., Giddings,B.W., Liu,J., Vito,M. and Weinberg,R.A.
  TITLE     Characterization of a guanine nucleotide dissociation stimulator
            for a ras-related GTPase
  JOURNAL   EMBO J. (1993) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             202..2889
                     /evidence="EXPERIMENTAL"
                     /note="'also known as exchange factor for the ralA and
                     ralB GTPases.'; 'ralGDSb is a member of the CDC25 family
                     of GDSproteins, which includes CDC25, SDC25, BUD5, LTE1,
                     ste6, SOS, mSOS-1, mSOS-2,CDC25-Mm, and Ras-GRF.'"
                     /product="guanine nucleotide dissociation stimulator"
                     /codon_start=1
                     /translation="MVQRMWAEASGPIGGAEPLFPGSRRSRSVWDAVRLEVGVPDSCP
                     VVLHSFTQLDPDLPRLESSTQEIGEELINGVIYSISLRKVQLYPGATKGQRWLGCENE
                     SALNLYETCKVRTVKAGTLEKLVEHLVPAFQGSDLSYVTVFLCTYRAFTTTQQVLDLL
                     FKRYGCILPYSSEDGGPQDQLKNAISSILGTWLDQYSEDFCQPPDFPCLKQLVAYVQL
                     NMPGSDLERRAHLLLAQLEDLEPSEVEPEALSPAPVLSLKPASQLEPAPALLLTPSRA
                     VASTPVREPAPVPVLASSPVVAPASELEPALEPPLDPEPTLAPAPELDPTVSQSLHLE
                     PAPVPAPALEPSWPLPETTENGLCAKPHLLLFPPDLVAEQFTLMDAELFKKVVPYHCL
                     GSIWSQRAKKGKEHLAPTIRATVAQFNNVANCVITTCLGDQSMKASDRARVVEHWIEV
                     ARECRVLKNFSSLYAILSALQSNAIHRLKKTWEEVSRGSFRVFQKLSEIFSDENNYSL
                     SRELLIKEGTSKFATLEMNPRRTQRRQKETGVIQGTVPYLGTFLTDLVMLDTAMKDYL
                     YGRLINFEKRRKEFEVIAQIKLLQSACNNYSIVPEEHFGAWFRAMGRLSEAESYNLSC
                     ELEPPSESASNTLRSKKSTAIVKRWERRQAPSTELSTSSSAHSKSCDQLRCSPYLSSG
                     DITDALSVHSAGSSTSDVEEINMSFVPESPDGQEKKFWESASQSSPETSGISSASSST
                     SSSSASTTPVSTTRTHKRSVSGVCSYSSSLPLYNQQVGDCCIIRVSLDVDNGNMYKSI
                     LVTSQDKAPTVIRKAMDKHNLDEDEPEDYELLQIISEDHKLKIPENANVFYAMNSAAN
                     YDFILKKRAFTKGAKVKHGASSTLPRMKQKGLRIARGIF"
BASE COUNT      806 a   1181 c    989 g    689 t
ORIGIN      
        1 ccaccaggcc taacaactag aggaggctta cggccctcgg aaaccacgcc cccatcagtc
       61 agtccccacc ctcagctgac atcagcgagt ccggccctgg gcgcagagcg caggcagcgc
      121 ggagccgcgc cggccggccc tgcgcccacg ccgccccggg tctcgcggcc cgccggccac
      181 ccgcgccacc gggagtcgtc catggtgcag cgcatgtggg ccgaggcgtc cgggcccata
      241 gggggcgccg agccgttgtt tcccggctcc cggcgcagcc gcagcgtgtg ggacgccgtg
      301 cgtctggagg tgggcgtccc tgacagctgt ccagtggtgc tgcacagctt cacgcagctc
      361 gaccccgatc tgccgcgcct ggagagctct acgcaggaga ttggggagga gctgatcaac
      421 ggggtcatct actccatctc cctgcgcaag gttcagctat acccaggagc caccaagggc
      481 cagcgctggc tagggtgcga gaatgagtca gctctgaacc tctacgagac ttgcaaggtg
      541 cgcacggtga aggccggtac tctggagaag ctggtggaac acctggtgcc tgccttccag
      601 ggcagtgacc tttcctacgt caccgtattc ctgtgcacct acagagcctt cacaaccact
      661 cagcaggtgc tagacctgct gttcaaaaga tatggctgca tccttcccta ctccagtgag
      721 gacggcggac cacaggacca actcaaaaat gccatctctt ccatcctggg cacctggctg
      781 gaccaatact ccgaggactt ctgtcaaccc ccggactttc cctgcctcaa gcagctggtg
      841 gcttatgtgc agctcaacat gcctggctca gacctggagc gccgtgctca ccttctcctg
      901 gcccagctgg aggacctgga gcccagtgag gttgagcctg aggccctgtc cccagctcca
      961 gtgctgtctc tgaaaccagc ttcacagcta gaaccagctc ccgccctgct tctgacgccc
     1021 agccgagctg tggcatccac tccagtacga gagccagccc cggtgccagt actggcatcc
     1081 agcccggtgg tggcgccagc ctctgagcta gaaccagctc tggagccgcc cctagaccct
     1141 gagccaaccc tcgcacctgc tccagagctg gaccccactg tctcacagag cctccacctc
     1201 gagcccgctc ccgtgcccgc tcctgcatta gagccttcct ggcctctgcc tgaaaccacg
     1261 gagaacggac tgtgtgcaaa gcctcaccta ctgctgttcc ctccagactt ggtggctgaa
     1321 cagtttacgc tgatggacgc agagctattc aagaaagttg tgccctacca ctgcctgggc
     1381 tccatctggt cccagcgggc aaagaagggc aaggagcacc tcgcgcccac catccgtgcc
     1441 actgtcgccc agttcaacaa cgtggccaac tgtgtcatca ccacctgcct tggggaccag
     1501 agtatgaaag cttcggacag ggcccgggtg gtggaacact ggatcgaggt ggccagggag
     1561 tgcagggtgc tcaagaattt ctcctccctc tacgccatcc tctctgccct acagagcaat
     1621 gccatccacc gcctaaagaa gacatgggaa gaggtctcca ggggcagctt tcgagtgttc
     1681 cagaaactgt cagaaatctt ctctgatgag aacaactact ccttgagcag agagctgctc
     1741 atcaaggaag gaacctccaa gtttgccacg ctggagatga accctaggag aacccagagg
     1801 cggcagaagg agacaggtgt catccagggc actgtcccct acctgggcac attcctcact
     1861 gacctggtga tgctggacac agccatgaag gactatctat atgggagact gatcaacttt
     1921 gaaaagagga ggaaggagtt cgaagtcatc gcccagatca agttgctcca gtcggcctgc
     1981 aacaactaca gcattgttcc cgaggagcac tttggagcct ggttccgagc catgggacgg
     2041 ctcagcgagg ctgagagcta caacctgtcg tgtgagctgg agcccccgtc tgagtcagcc
     2101 agcaacaccc tgaggagcaa gaaaagcaca gctatcgtca agcgctggga gcgacgccag
     2161 gctcccagca cggagctcag caccagtagc agtgcacact ccaagtcatg tgaccagctc
     2221 cggtgcagcc cctacctcag cagcggggac atcacggacg cactcagtgt gcactcagct
     2281 ggttcatcca cgtctgacgt ggaggagatc aacatgagct ttgttccaga gtctcctgat
     2341 ggccaggaaa agaagttctg ggagtcagcc tcccagtcgt ccccagagac ctctggcatc
     2401 agctcggcct ccagcagcac ctcctcttcg tcagcctcta ccacaccggt gtctaccaca
     2461 cgcacccaca agcgctctgt ctcaggggtc tgcagctaca gctcctcact gccactctac
     2521 aaccagcagg tgggcgactg ctgcatcatc agggtcagcc tggatgtgga caacggcaac
     2581 atgtacaaga gcatcctggt gaccagccag gataaggctc cgactgtcat ccggaaagcc
     2641 atggacaaac acaacctaga tgaggacgag cccgaggact atgagctgct gcagatcatc
     2701 tcagaggacc acaagctgaa aattccagag aacgccaatg tgttctatgc catgaactct
     2761 gccgccaact atgacttcat cctaaagaag cgggccttca ctaagggggc taaagtcaag
     2821 catggagcca gctccactct ccctcgaatg aagcagaagg gactcaggat tgccagaggc
     2881 atcttctaag gacgtctccc aggggctggc tggctggctg gggactaagc acttacagac
     2941 tagagtggcc caggccacag gtacctctgc cctcctgcca gcccaggcta ctcccagact
     3001 ccactttcac cccgaacctg tcctgctgcc gggattgaca cctgccactg acaggctgac
     3061 ctggcctccg gggaccgctc accgccttag gtgccttctg ctctctgcaa ccagaggact
     3121 agctgacttt gccaaggggt gctgccagct gggcatggag cctcgcctgc cctggacaat
     3181 gtccaccaca ctttcctgtc acctccccaa gtgcagatca ctgccaccca tgctcccaga
     3241 tgctccagga cacccacaca cccagcgggg ctgccaactg cgttctctcc ttgtgcccat
     3301 aggccatggc ctgggacctt catggaggtc ctagcctttc ttaggctgca ccaaagattc
     3361 caccttcagg cctacagagt gagggagtct cgcccaccac gagcccaagc cctcccatgg
     3421 atcagagaga gaagccctct catggaccgc ctggttggca ttgaacccca taccactgaa
     3481 agtgccattc accaccgctg cgtcccgggt gtacaagact acatgcaatg ggaggtttgt
     3541 ggggaggggg aagacgactg gatatttgta taaaacgtaa aaagtttact gattggggtg
     3601 gggcaatatt tatttgttgt aaatagaaaa tgctagactt gaatattata ttaaaatccc
     3661 gtttc
//