From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat H+,K+-ATPase mRNA, complete cds.
Date: 28 Jul 92 10:07:51 GMT
Distribution: bionet
Checksum: 37894     8

LOCUS       RATATPASEZ   3942 bp ss-mRNA            ROD       28-JUL-1992
DEFINITION  Rat H+,K+-ATPase mRNA, complete cds.
ACCESSION   M90398
KEYWORDS    H+,K+-ATPase.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) colon cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3942)
  AUTHORS   Crowson,M.S. and Shull,G.E.
  TITLE     Isolation and characterization of a cDNA encoding the putative
            distal colon H+, K+-ATPase: Similarity of deduced amino acid
            sequence to gastric H=,K+-ATPase and mRNA expression in distal
            colon, kidney, and uterus
  JOURNAL   J. Biol. Chem. 267, 13740-13748 (1992)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             203..3313
                     /product="H+,K+-ATPase"
                     /gene="H+,K+-ATPase"
                     /codon_start=1
                     /translation="MRRKTEIYSVELNGTKDVKPADQRDDKKFKGAKNKDLEPNKSHE
                     KEELKKELDLDDHRLSNTELEQKYGTNIIQGLSSVRATELLARDGPNTLTPPKQTPEI
                     IKFLKQMVGGFSILLWIGAALCWIAFVIQYVNNSASLDNVYLGAILVLVVILTGIFAY
                     YQEAKSTNIMASFSKMIPQQALVIRDAEKKVISAEQLVVGDVVEIKGGDQIPADIRLV
                     FSQGCKVDNSSLTGESEPQARSTEFTHENPLETKNIGFYSTTCLEGTATGIVINTGDR
                     TIIGRIASLASGVGSEKTPIAIEIEHFVHIVAGVAVSIDIIFFITAVCMKYYVLDAII
                     FLISIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGT
                     LTQNRMTVAHLWFDNQIFVADTSENQTKQAFDQSSGTWASLSKIITLCNRAEFRPGQE
                     SVPIMKRTVVGDASETALLKFSEVILGDVMGIRKRNHKVAEIPFNSTNKFQLSIHETE
                     DPNNKRFLVVMKGAPERILEKCSTIMINGQEQPLDKSSADSFHTAYMELGGLGERVLG
                     FCHLYLPAEQFPQSYIFDVDSVNFPTSNFCFVGLLSMIDPPRSTVPDAVSKCRSAGIK
                     VIMVTGDHPITAKAIAKSVGIISANNETVEDIAKRRNIAVEQVNKREAKAAVVTGMEL
                     KDMTPEQLDELLTNYQEIVFARTSPQQKLIIVEGCQRQDAIVAVTGDGVNDSPALKKA
                     DIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYTLTKNIAE
                     LCPFLIYIVAGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKKKDRL
                     VNTQLAIYSYLHIGLMQALGGFLVYFTVYAQQGFWPTSLINLRVAWETDDINDLEDSY
                     GQEWTRYQRKYLEWTGSTAFFVAIMIQQIADLIIRKTRRNSIFQQGLFRNKVIWVGIA
                     SQVIVALILSYGLGSVPALSFTMLRVQYWFVAVPHAILIWVYDEMRKLFIRLYPGSWW
                     DKNMYY"
     polyA_signal    3919..3925
                     /gene="H+,K+-ATPase"
     polyA_site      3942
                     /gene="H+,K+-ATPase"
BASE COUNT     1054 a    972 c    955 g    961 t
ORIGIN
        1 ggccttcacc actcagggac ccggacctca acacccgccg cggccgcggc agccgccacc
       61 aaaagttcag acttgattct gtgaaccaca gtccggcgcg cgctaaagca acgcgcatct
      121 tcacgcctat ccggctcacc tcaacaggcc agcatccggt gtcttacatc gtttgccagc
      181 gggttggacc accagccaca gtatgcgccg gaaaacagaa atttattctg tagagctcaa
      241 cggaactaaa gacgtcaagc cagcagacca gagggatgac aaaaagttca aaggagcgaa
      301 gaacaaggac ttggaaccca acaagagtca cgagaaagag gagctgaaga aagaacttga
      361 tctggatgat cacagactca gtaatacaga attggaacag aaatatggta ccaacatcat
      421 ccagggtctc tccagcgtca gagctacaga gctcctggct cgggatgggc ccaacactct
      481 tacccctccc aagcaaactc cagagattat caagttcctc aagcagatgg tggggggctt
      541 ttccatcctc ctgtggatag gtgctgcctt gtgctggatc gcatttgtga tccagtacgt
      601 caacaattcc gcatccctag acaacgtcta cttgggcgcc atacttgtcc tggttgttat
      661 tttaacgggg atttttgctt attaccaaga agccaaaagc accaacatca tggccagctt
      721 tagtaagatg atcccccagc aagctcttgt catccgagat gccgaaaaga aggtcatttc
      781 agcagagcaa ctggtggtgg gggacgttgt ggagattaaa ggaggggacc agatccctgc
      841 agacatcaga ctggtatttt cccaagggtg caaagtagat aactcctctc tcactgggga
      901 atctgagccc caggctcgtt caactgagtt tacccatgaa aaccccttgg aaaccaagaa
      961 cataggcttc tattccacaa cctgcctgga aggtacagca actggcattg tcatcaacac
     1021 gggtgaccgt accatcatcg ggcgcatagc ctccttggct tcaggcgttg ggagtgagaa
     1081 aacacccatt gccattgaga tcgagcattt tgtccatatt gtggcaggag tggctgtgtc
     1141 cattgacatc attttcttca tcaccgccgt gtgcatgaag tactatgtcc tcgacgccat
     1201 catcttcctc attagcatca ttgtggctaa cgtgccagag ggcctcctgg ctactgtcac
     1261 tgttaccctg tcactgacgg caaaacggat ggccaagaag aactgcctgg taaagaatct
     1321 ggaggcagtg gagactcttg gctccacctc catcatctgc tcagacaaga cggggaccct
     1381 gacccagaac aggatgactg tggctcactt gtggtttgac aatcagatct ttgtggctga
     1441 tactagtgaa aaccaaacaa aacaagcctt tgaccaaagc tctggaacct gggcttcctt
     1501 gtccaagata ataacactgt gtaaccgagc agagttcagg ccaggccagg agagtgtccc
     1561 catcatgaag agaactgtgg ttggagacgc ctcagaaact gctctgctaa agttctcaga
     1621 ggtcattttg ggtgacgtga tgggaattag gaaaagaaac cacaaagtgg ctgaaattcc
     1681 ttttaattct accaacaaat ttcagctctc catacatgag acagaggacc ctaataacaa
     1741 acgcttcctc gtggtgatga aaggagcccc tgagaggatc ttagagaagt gcagcaccat
     1801 catgatcaat ggccaggagc agccactgga caagagctct gctgatagct tccacacagc
     1861 ctacatggag ctgggcggtc tgggcgagcg tgtgttgggt ttctgtcacc tctacttgcc
     1921 agcagagcag ttcccccaaa gttacatctt tgatgtcgac tccgtaaact ttcccacttc
     1981 caacttctgc tttgtggggc ttctgtccat gatcgaccct cctcggtcta ctgtgccaga
     2041 cgcagtctcc aaatgtcgga gtgccgggat caaggttatc atggtcacag gtgatcaccc
     2101 tatcaccgcc aaagctattg ccaagagtgt aggaatcata tcggccaaca acgagacagt
     2161 ggaagacatc gcgaaacgcc gcaatatcgc tgtggagcag gtcaacaaaa gagaagctaa
     2221 agccgctgtg gtgactggca tggagctgaa ggacatgacc ccagaacaac tggatgagct
     2281 tttgaccaac taccaagaaa tcgtatttgc ccggacatca ccccagcaga agttgatcat
     2341 tgtggagggc tgtcagaggc aggacgccat cgttgccgtg acgggtgatg gagtgaacga
     2401 ctctccagca ctgaagaagg cagacatcgg gattgctatg gggatagcag gttctgacgc
     2461 tgctaagaac gcagctgaca tggtcttact agacgacaac ttcgcgtcta tagtcacagg
     2521 ggtggaggaa ggtcgcctga tcttcgacaa cctgaagaaa accattgcgt acaccctgac
     2581 aaagaacatc gccgagctct gccctttttt gatctacatc gttgctgggc tccccctgcc
     2641 tattggaacc atcactatcc tattcatcga cctgggcaca gacattatcc cctccattgc
     2701 cttggcctat gagaaagcag aaagtgacat tatgaatagg aaacctcgcc acaagaagaa
     2761 agacagactg gtgaacacgc agctggccat ctactcttac cttcacattg gtctcatgca
     2821 agctctggga ggtttcctcg tctatttcac tgtctatgca cagcagggct tttggcccac
     2881 ttctctcatc aacctgaggg tagcatggga aacagatgac ataaatgact tggaagacag
     2941 ctacgggcag gaatggacaa ggtatcagag aaaatacctg gaatggacag gctcaacggc
     3001 tttctttgtt gccatcatga tccaacaaat tgcggatctg atcatcagga aaacccggag
     3061 gaattccatc tttcagcagg ggctcttcag aaataaagtc atctgggtgg ggatcgcctc
     3121 acaggtcatc gttgcactga tcctctccta tggtctcggg agtgtcccag ctctgagctt
     3181 taccatgctc agggttcagt actggtttgt ggctgtgcca catgccattt tgatttgggt
     3241 gtatgacgag atgcgaaagt tgttcatcag gctctaccct ggaagctggt gggataagaa
     3301 catgtattat tgagaccatg tcactcacag gtctcccagt ggcctatcag aggtgttctt
     3361 cgtcaagttt ggctacactt cggagatctc tgcacaatgt gaatgctacc aaaccccaca
     3421 tgagagagac ttttggacag aaaactgtat gaagcatact taggttttgt attttaaagc
     3481 tgagatttaa ctgtttatat agaatgttca tctctatgtc tgcctcttaa ttttaaatga
     3541 tgtgaatttc agatatcagc atagggaagg atatatttat gtgtatgtaa aggtactgtg
     3601 ttaaatagcc ttgtatatcc aaggcatgtg ctggggtctg ccctaagcta gactatgatt
     3661 cctcaggcct tactttctta ctctcctaga ggcccaacag accccctaaa tccaccaagc
     3721 aaactttctg tttgctggag tttaacctca ggcaaagagt accagtgact taagcagtaa
     3781 tatttatttc tagtaaaaca ttgtcaacgt ctcgccagca atcattttgt gtcagtcatg
     3841 tgttgtgttg taactgttag atgtattcat gtgtgacatg tgtgactaga ttggcaggtc
     3901 cagtgaggcc tcgtttttaa gtaaaagatg ttttctaaag cc
//