From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus meprin beta-subunit mRNA, complete cds.
Date: 28 Jul 92 10:07:52 GMT
Distribution: bionet
Checksum: 23877     5

LOCUS       RATMEPRIN    2306 bp ss-mRNA            ROD       28-JUL-1992
DEFINITION  Rattus norvegicus meprin beta-subunit mRNA, complete cds.
ACCESSION   M88601
KEYWORDS    ectoenzyme; meprin beta-subunit; metalloendopeptidase;
            transmembrane protein.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) adult kidney cDNA to
            mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2306)
  AUTHORS   Johnson,G.D. and Hersh,L.B.
  TITLE     Cloning a rat meprin cDNA reveals the enzyme is a heterodimer
  JOURNAL   J. Biol. Chem. 267, 13505-13512 (1992)
  STANDARD  full staff_review
FEATURES             Location/Qualifiers
     CDS             27..2033
                     /EC_number="3.4.24.18"
                     /product="meprin beta-subunit"
                     /gene="meprin beta-subunit"
                     /codon_start=1
                     /translation="MDARHWPWFLVFATFLLVSGLPAPEKFVKDIDGGIDQDIFDINE
                     DLGLDLFEGDIKLEASGRNSIIGDNYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLK
                     TCIDFKPWSGEENYISVFKGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALG
                     FWHEQSRADRDDYITIVWDRILSGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQ
                     NGTESTIITKISDFEDVIGQRMDFSDYDLLKLNQLYSCTSSLSFMDSCDFELENICGM
                     IQSSQDSADWQRLSQVLSGPENDHSNMGQCKDSGFFMHFNTSTGNGGITAMLESRVLY
                     PKRGFQCVEFYLYNSGSGNGQLNVYTREYTAGHQDGVLTLQREIRDIPTGSWQLYYVT
                     LQVTEKFRVVFEGVGGPGASSGGLSIDDINLSETRCPHHIWHIQNFTQLLGGQTTVYS
                     PPFYSSKGYAFQINLDLTSPTNVGLYFHLISGANDDQLQWPCPWQQATMTLLDQNPDI
                     RQRMSNQRSITTDPKMTDDNGSYLWDRPSKVGVEAFFPNGTQFSRGRGYGTSVFITQE
                     RLKSREFLKGDDVYILLTVEDISHLNSTAAVPGQSPPPRLSIMPALRSNVRTAASALS
                     KKAELSASVLQEKTGGTWAKGVRREGPPRTRLSLLCLPRSPCLP"
BASE COUNT      646 a    540 c    567 g    553 t
ORIGIN
        1 gagcttgcaa ctttgaaagc cacagtatgg atgcccggca ttggccctgg tttctggttt
       61 ttgccacatt tctcctggtt tctggcttgc cagctccaga aaagtttgtc aaagacatag
      121 atgggggaat cgatcaagac atattcgata tcaatgaaga tttaggactg gaccttttcg
      181 agggagacat caaactggag gcaagtggga ggaattccat cattggagac aactacagat
      241 ggccacatac cattccatat gttctagaag acagcttgga aatgaatgct aaaggagtaa
      301 tcctcaatgc gttcgagcgc tatcgcctta aaacgtgcat tgacttcaag ccctggtctg
      361 gagaagagaa ctatatatca gtgttcaagg gcagtgggtg ctggtcttca gtgggaaaca
      421 ttcacgctgg gaagcaagag ttgtccatcg ggacaaactg tgacagaata gcaacagttc
      481 aacatgagtt cctccacgcc ctgggattct ggcacgagca gtcgcgtgct gaccgagatg
      541 attacatcac tatagtttgg gacaggatct tgtccggcaa ggaacacaat ttcaacatct
      601 acaacgacag tgtgtctgat tccctgaatg tcccatacga ctacacctcg gtaatgcact
      661 acagcaaaac cgctttccag aatgggacag agtctaccat cattacgaaa atctcagact
      721 ttgaggatgt gattggccaa cgaatggact tcagtgacta tgaccttctg aagctgaacc
      781 agctgtacag ctgcacttct tccttgagtt ttatggactc ctgcgatttt gagctggaga
      841 atatctgtgg catgatccaa agttcacaag atagcgctga ctggcagcgg ctttcacagg
      901 ttctcagtgg tccggagaat gaccactcca acatgggcca gtgcaaagac tctggcttct
      961 ttatgcactt caacactagc actgggaatg gggggatcac agcgatgctg gagagcagag
     1021 tgctgtaccc caagagaggg tttcagtgcg tggagtttta tctgtataac agtggaagtg
     1081 gaaatggcca actgaacgtc tacacccggg agtacactgc aggccaccag gatggcgttt
     1141 tgacccttca gagagaaata agagacatac ccactgggag ctggcagctt tactatgtaa
     1201 cactgcaagt gactgaaaaa ttccgagtgg tgtttgaagg cgtcggaggc cctggcgcat
     1261 catcgggtgg tctgtctatc gatgacatca atctctcgga aacaaggtgt ccccaccaca
     1321 tctggcacat acagaatttc actcagcttc ttggaggcca gaccactgta tacagtcctc
     1381 cattttattc ctctaaaggt tacgcttttc agattaacct ggatctaaca tccccgacca
     1441 atgtagggct ttatttccac ctgatctccg gggccaatga cgatcaatta cagtggccgt
     1501 gtccttggca gcaagccaca atgacactct tggatcagaa tcctgacatc cggcagcgta
     1561 tgtccaacca gcggagtata accacagacc caaagatgac cgatgataat ggaagctatc
     1621 tttgggacag gccttccaag gtgggagtgg aggctttttt ccctaatgga actcagttta
     1681 gcagaggcag aggctatgga accagtgtct tcataaccca agagaggctg aagagcagag
     1741 agttcttaaa aggagatgac gtttacatct tactgacggt tgaagatata tctcacctca
     1801 attctacagc ggctgtccca ggccagtccc caccacctcg actgtccata atgcctgctc
     1861 tgaggtcgaa tgtcagaacg gcggcatctg cactctccaa gaaggcagag ctgagtgcaa
     1921 gtgtcctgca ggagaagact ggtggtacat gggcaaaagg tgtgagaaga gagggtccac
     1981 caaggacacg attgtcattg ctgtgtcttc cacggtcacc gtgtttgccg tgatgctgat
     2041 catcaccctt atcagcgtct actgcacccg gaggaaatat cgtaagaagg ctagtgcaaa
     2101 gacagcagcc atgaatctag aaaaccaaca tgcgttttga atattaactc gtgccagcag
     2161 gtgaaacaaa aagaaacctt ctgtcgtcgt agaagaatat ttcgcccagg ctgtgcgacg
     2221 acattcacag catttcaaac cagaccatct ctgtaaatag ctgagtgcct aataaaccat
     2281 tattttggta aaaaaaaaaa aaaaaa
//