From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human nerve growth factor beta (beta-NGF) gene, segment 2.
Date: 5 Nov 92 23:11:41 GMT
Distribution: bionet
Checksum: 12666 9

LOCUS       HUMNGFBA2    5778 bp ds-DNA             PRI       15-DEC-1988
DEFINITION  Human nerve growth factor beta (beta-NGF) gene, segment 2.
ACCESSION   M21062 M14806
KEYWORDS    nerve growth factor.
SEGMENT     2 of 2
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 5778)
  AUTHORS   Ullrich,A., Gray,A., Berman,C.H., Coussens,L. and Dull,T.J.
  TITLE     Sequence homology of human and mouse beta-NGF subunit genes
  JOURNAL   Cold Spring Harb. Symp. Quant. Biol. 48, 435-442 (1983)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mat_peptide     3681..4034
                     /product="nerve growth factor beta"
                     /gene="NGFB"
                     /codon_start=1
     CDS             3318..4043
                     /gene="NGFB"
                     /product="nerve growth factor beta"
                     /codon_start=1
                     /translation="MSMLFYTLITAFLIGIQAEPHSESNVPAGHTIPQVHWTKLQHSL
                     DTALRRARSAPAAAIAARVAGQTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQD
                     LDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVL
                     GEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQA
                     AWRFIRIDTACVCVLSRKAVRRA"
BASE COUNT     1681 a   1284 c   1436 g   1377 t
ORIGIN      About 2.8 kb after segment 1.
        1 ggcagagcag tccctactgg cttacagaca agggacttgg caccagctcc tttgagcagg
       61 gtgatatgat cagagcaggc tttaagaagc taaatggggt ggccagggat aggaggaatt
      121 ggaagaagag agatgagggt ccaggatatc aggtgggaga ctgttcccat gacctgaact
      181 aggggcccag agatgagaat ggaagataaa atacagtttc aagataatgc taccaaacca
      241 gaaccaaaag ggctggatgg aggtcaggga ggaaaaagca gagggataag cagaggtatg
      301 gagctagtgg atgaatgaat gatggttcca gtaacagaaa aaggaaactg tgaagaagcg
      361 tgtttaggga gatgaggaga gaggatcaag agagatggta gctgtgaaaa ctatcatcaa
      421 atggtttcaa aatggggctg ttgctattgt atgcagagaa ggaagatggg gagaagatga
      481 tcctaattat gattatgagt atgaagattt ttgttttggt agtcttgcat ttaaaatgcc
      541 agtatctatg gagaattgcc ctcaggaagc aggagggcag aactagcttc aaaagactag
      601 ttgattagag atccaggtat gggagtcaat tgcacagaaa tttcgatggg ctccttagaa
      661 gaggaggagc ccaccaaagg agagaccaag aatcgaagtg ggaacctctg gtaatgggga
      721 atagggagag gtatgtccct tatgtccatc gaaacccttt tatttagtta atttcatttt
      781 cctcttgaaa ttctagcaag tgttactaat ttggatataa gggaatgaat ttcagttttc
      841 tttcttctcc tttaatgtat ctgataagag atattatgta ccgagaagaa caaagaagtg
      901 aaacatgaaa aggagcaaaa gtaaaaggtt tagatttgct gccaactgaa tattcagtcc
      961 gctaagagtt gaccggacat ttatcgcaag accattaaca gatctggtaa tggtcaaaac
     1021 cccagatatg ccattgcctc ctttgcatgg tcagctggag aactggagca aacagaaaca
     1081 ttcttcaaag aaaccaaaga gaaaagaatt tggtgatttc cttcttggta tctcaccaaa
     1141 gagctgtcta tttccagctg aataaaagca cagtatggag gagaagaatg tgttgcctta
     1201 aaacagatta gaaaagcagt gtgtagccat atgcacaaag gccaaaagaa accacacact
     1261 gtgatggaaa gaaggcagat ggtgagcttc tcttgccact ctcattcatt ctttctttca
     1321 ttcattctcc ttaaattttt tgagtaccta ctacatgcca gacacggcaa ctggccctgg
     1381 aaatattgaa atgcaaattg tgcagcttgc aaagccctct cagggagaca gacaagttaa
     1441 tgattatcca caaccctagg agaggtgata gggttatgca caaactgctg tggaatacaa
     1501 gggatggagt gcccagatac acaagtggat gagacacggc tccaccctcg agtacctcac
     1561 agtcggggtg agacaataaa aatggctttg aaggaggtct gagagaggta aaaccgcgtg
     1621 aaagcacaaa agacaaagtc cttgaccaca aggagacaga aataactcat gatttacaca
     1681 aattttgtga gaacctactt catcctaaca actactctgg gagatagtgt tttttgccca
     1741 cctccgatca atgggaacgc taaggctctg ggaaattaaa tgggtttctt ctgctaacaa
     1801 gtagtggagt aggaatccaa acacgatttt ctaaccccca gacccaatgc agagttcttg
     1861 tcattacact gatttagtag gagagaacac acacactcac actcacatga acacacacat
     1921 atgcacatac aattacgcta ttctgaagtg cagaatggca aaagatcatt tttgattgga
     1981 gtgatctgag aaggcttcga ggactaggtc gtatctgtgt ggaaacggag cagaatgacc
     2041 cataagagtg ggaaggagag atgggagaaa ggatagaatt ggaagtttgt agagcactct
     2101 tacaggagat atttctgatc ctaccaggaa gatctatgga agctttacag aggagctgac
     2161 gtttgctaca catctacaag tatgcatagg agctccgcgg aggccagtga gaggccctcc
     2221 aggagcagaa ctaattccac aattacttga ccaagttggg ggattatttg tggggtaact
     2281 gcagtgcagt atggagtcct cttggggaca gttagagcca taccatttga tctatagtca
     2341 cataagaaca aacaataaaa agaaaagaca tgcttaagag tgaaagagaa agggagggag
     2401 aaaagaagga agggtggatg gaaggacact agcttagtaa ggggtcaact ttggattcta
     2461 tttctggttc agttttcatt tgtgacttca gtgctttagt gttagttcat tttctgtgaa
     2521 tcagtttcct tatatgtgaa ataaatatga taaatcctaa ttgaactcac agactcatga
     2581 gaagatagaa gtgaacacat tttaaaaaca tcacacaaag aggaactatt atgtggtcca
     2641 catttatata tgtggggtag cgtctgaaga ggtgcctgga ctaagatggt cccagagcca
     2701 caaggttttt gccaaacatg acgctttgtg aattcataac aagggctcca agtcaccaga
     2761 tcttagagct gacccagtgc actgtctgaa agggggtacc agttctgagg cttcaagaca
     2821 tgtccccagc agatcttccc cgtgccttcc cagaggattc aaaactgttg agcaggacgg
     2881 caccatcaca tcaaggcaca agtgccaggg agaggtgtta aactctcccc accaacctcc
     2941 ctggtacaca catggacact tgccacctcc ctcagccgcc ttaagcttca gagaactcaa
     3001 aggactctgt aagtgatgtc tccaagctca tatcgaacta ctgggcaaaa tttcaggggc
     3061 tctgtcactt cctggagaag ctcggatggg gtgaccacac atccatactg cctgagtcag
     3121 ccccgggtta cgcctgttgt cccggtataa ccattgctag cacacccttt ccctctcaga
     3181 agtgccccgg tttgaatgaa acctcttcgt gatccccttg gaggtcaact ctgagggacc
     3241 cagaaactgc cttttgactg catttagtac tccatgaagt caccctcatt tctttttcat
     3301 tccaggtgca tagcgtaatg tccatgttgt tctacactct gatcacagct tttctgatcg
     3361 gcatacaggc ggaaccacac tcagagagca atgtccctgc aggacacacc atcccccaag
     3421 tccactggac taaacttcag cattcccttg acactgccct tcgcagagcc cgcagcgccc
     3481 cggcagcggc gatagctgca cgcgtggcgg ggcagacccg caacattact gtggacccca
     3541 ggctgtttaa aaagcggcga ctccgttcac cccgtgtgct gtttagcacc cagcctcccc
     3601 gtgaagctgc agacactcag gatctggact tcgaggtcgg tggtgctgcc cccttcaaca
     3661 ggactcacag gagcaagcgg tcatcatccc atcccatctt ccacaggggc gaattctcgg
     3721 tgtgtgacag tgtcagcgtg tgggttgggg ataagaccac cgccacagac atcaagggca
     3781 aggaggtgat ggtgttggga gaggtgaaca ttaacaacag tgtattcaaa cagtactttt
     3841 ttgagaccaa gtgccgggac ccaaatcccg ttgacagcgg gtgccggggc attgactcaa
     3901 agcactggaa ctcatattgt accacgactc acacctttgt caaggcgctg accatggatg
     3961 gcaagcaggc tgcctggcgg tttatccgga tagatacggc ctgtgtgtgt gtgctcagca
     4021 ggaaggctgt gagaagagcc tgacctgccg acacgctccc tccccctgcc ccttctacac
     4081 tctcctgggc ccctccctac ctcaacctgt aaattatttt aaattataag gactgcatgg
     4141 taatttatag tttatacagt tttaaagaat cattatttat taaatttttg gaagcatcct
     4201 gtgtgctgat gctggttatt ttttttgagt aaaatcatct gcaagtctga ggaagatgca
     4261 gggggaattg tctgaagcac cccctggctc cttctaaggc ccacctgtaa cccttacccc
     4321 acccccagcc agtgctgcaa cttcaggaaa ggctaactgg tttcagatat tagcctaagc
     4381 caggcatgat tagcaaagga agcctgctgg attgcaactt tgttctacat tccagagcca
     4441 aagctaccta atcattggat tacctgccca cggcctggaa gcatgggccc tggctcctcc
     4501 cttggagaag ttagtggagc ctcatcagga ggcagatcac cactgggcat ggggctgccc
     4561 tggcctcaga ggcacagtct cagtcctggg ggcactcgat agacaggaag aggcttgtac
     4621 caaagatctg tgagctgctc atttgtagag ggagtgtgct gtctggagag ttgtaacaga
     4681 gtaactcacg aagcctgcca aagtaagatc tagggtttca tgttcagctg gccttagtac
     4741 tcgttttatc cctcagcagc ctcctgcaga aagactttca ttaccccaag aaaacattag
     4801 tgcctccgac actcttgcaa cccactaaca gccacagtag caacttccag gggccccacc
     4861 atcagcccac agccagggaa gccagagacg ggagagaact tctgaaaata tttttattct
     4921 taattggatg atttccataa gtgaccaaag gtgactgggg ccgtgggacc tgcagagaag
     4981 agggtggggc agaaagacta agtaaatgga gtaagaacca aataaacctg gagatgtgga
     5041 ggacaggtgg gccggcagga accacggctt tctgcttctc ccaaacaggg gaaatgaaac
     5101 aaggatgaca aagagaaggc cagaggtgga tgtgaagaag gggaggggag gacagagcag
     5161 gaggaggagg gaggtgtgat ctctcatctt taccagcact ctccagcctc caggaaagtt
     5221 agcaacctgg gtggttcttg tggggctttt tggatgtgct aataaacact gactccatcc
     5281 agagcatctt aggagtgaag gtgacagagg gactccaggg ttcagcctgc agcagggctc
     5341 cacccagcct cacacgaccc ccttcccctg caactttcat tttgtatttt ccttgaagcc
     5401 acaatattcc cccagacaga gcacttatat taagacagaa aatttcccct cctatccatc
     5461 ctgtctcccc ccgaggatga aatgcctaca ctggttttca agagaacagg cccaaattgt
     5521 ccatccgaga aaagagcaaa tggtcttatt cattccctct gtaatcctcg ctgtccggcc
     5581 ccacctccaa cgccatccaa atagggcaaa ttagaaacgt agggagcttt ggcatgagag
     5641 ccatttgatt agggtagaag tatgatgaaa tgtgccctgt tttttctatc agagccactg
     5701 caattggaat aaaggtttat gctcaagaaa caccagctag aacattctgt gctgagattc
     5761 taagtgagat aaaggcat
//