From: vvl2h@galen.med.Virginia.EDU (Victor V. Levenson)
Subject: Vaccinologist/immunologist is looking for a job
Organization: University of Virginia
Distribution: usa
Date: Sun, 4 Oct 1992 20:41:03 GMT



Dear netters;

This is a posting for my father. You may contact him at his post-mail 
address below or send a message to me at vvl2h@virginia.edu.
                                            Victor Levenson


=========================================================================
Dear Sir/Madam;

I am looking for an appropriate position in experimental immunology. Before 
my recent immigration from Russia I worked in the field of bacterial antigens
and vaccines. I have a degree of Doctor of Medical Sciences in Immunology
(1970) and considerable experience in experimental work. Some ideas
concerning development of bacterial vaccines can be used both in research
and in production of bacterial vaccines foe medicine and veterinary.

If you happen to have a position or some information relevant to my
situation please contact me via e-mail or conventional mail at 
addresses provided.

                               Thank you,

                                            Vadim Levenson.

===================================================================

                        CURRICULUM VITAE

September, 1992


OBJECTIVE: 
     Position in bacterial vaccinology or immunology of bacterial infections 
(basic or applied studies).

EDUCATION: 
     Candidate of Science (=PhD) in Pathology in 1960; 1st Moscow Medical 
       Institute, Moscow, USSR: "Problems of thyroid histopathology: 
       autoradiographic study".

     Doctor of Medical Sciences in Immunology in 1970; All-Union Acad.of 
       Medical Sciences, Moscow, USSR: "Regulation of the immune response. 
       The experimental study with somatic antigens of typhoid bacteria".


EXPERIENCE:

     1970-present   Head of the laboratory of subcellular vaccines
                      Moscow Inst. Epidemiol. Microbiol.
     
     1960-1970      Junior and then Senior Research Fellow in 
                      Immunology; Moscow Inst. Epidemiol. Microbiol.

     1954-1960      Graduate student in Pathology; 1st Moscow 
                       Medical Institute.

=================================================================

    My early work was concerned with antigens of Shigella, Salmonella, 
Pasteurella and other bacteria as well as bacterial LPS. Polysaccharide 
Vi-antigen was studied as an inducer of antibody production, cutaneous 
anaphilaxy and immunological tolerance in animal and as a potential 
vaccine component in humans.Flagellins from different Salmonella sp. were
isolated and used for serological diagnosis in the clinic of infectious 
diseases.

     Recent studies were devoted to bacterial vaccines and endotoxin with 
special reference to RNP-associated antigenic complexes that have been 
previously described as potential ribosomal vaccines. Extended investigation 
of their nature employed different chemical and physical methods
(chromatography, electron microscopy, density ultracentrifugation, etc.) 
Immunological studies proved high protection activity of some of 
preparations. Vaccines from two Shigella sp. and from P.multocida seem 
to be very effective and therefore promising for use as vaccines for 
humans and animals resp.

     The work on Shigella vaccine was supported by WHO grant.

     An inexpensive method was developed for large-scale production of 
protective RNP-antigenic complexes.

     I firmly believe that this approach can be further developed to obtain 
various immunogenic preparations, vastly superior in their protective 
activity to currently produced vaccines.

     The LPS-associated protein (LAP) in Shigella endotoxin preparations 
was studied as a possible component of vaccines against Gram-negative 
infections.

     My scientific interests are not limited by the above-mentioned areas. 
Suggestions concerning other fields of experimental immunology or vaccine 
production can be also considered. I am experienced in current literature, 
planning experiments and critical evaluation of results.

PUBLICATIONS: 
     
     A total of about 150 papers, experimental and reviews, were published, 
mostly in Russian.

    Following papers appeared in English:

 1. Levenson V.I., Braude N.I. Different forms of interaction of  
     macrophages with foreign antigens provided by "early" and    
    "late" immune sera. Folia Biologica (Praha) 1967, 13, 113-120

 2. Levenson V.I., German G.P., Chernokhvostova E.V. Immunologic  
    response to somatic antigens of S.typhi in mice. ibid, 1971, 
    17, 136-147.

 3. Levenson V.I., Braude N.I., Chernokhvostova E.V. Adherence   
    promoting antibodies. The investigation of physico-chemical  
    properties of mouse anti-Vi antibodies providing immune        
    fixation of antigen to macrophage surface.                     
    Austr.J.Exp.Biol.Med.Sci. 1970. 48, 417-427

 4. Levenson V.I. Cytophilic properties of immune complexes. In:   
    "Antigen-Antibody Reaction" 1971, pp.111-115. Eds. H.Ambrosius,
     K.Malberg, H.Schaffner. VEB Gustav Fischer Verlag, Jena.

 5. Dzikidze E.K., Stasilevitch Z.K., Kavtaradze K.N., Levenson    
    V.I. Experimental study of Shigella ribosomal vaccine in       
    monkeys. In: "Bacteria and the Host" 1986, 365-368. Eds. M.Ryc,
    J.Franek. Praha.

 6. Levenson V.I., Chernokhvostova E.V., Lyubinskaya M.M. et al.   
    Parenteral immunisation with Shigella ribosomal vaccine elicits
    local immune response and primes for mucosal memory.           
    Int.Arch.Allergy Appl.Immunol, 1988, 87, 25-31.

 7. Chernokhvostova E.V., Lyubinskaya M.M., Belkin Z.P., Levenson  
    V.I. Protective milk antibodies induced in guinea pigs by      
    parenteral Shigella ribosomal vaccine. Int.Arch.Allergy        
    Appl.Immunol, 1990, 92, 265-267. 

 8. Levenson V.I., Egorova T.P. Polysaccharide nature of O-antigen 
    in protective ribosomal preparations from Shigella. Res. in    
    Microbiol., 1990, 141, 707-720.

 9. Levenson V.I., Egorova T.P., Belkin Z.P. et al. Protective     
    ribosomal preparations from Shigella sonnei as a parenteral    
    candidate vaccine. Infection and Immunity, 1991, 59, 3610-3618.

10. Levenson V.I., Egorova T.P., Dushuk R.V. et al. High protective
    activity of ribosomal vaccine against Pasteurella multocida    
    infection in rabbits and swine. Submitted to Infect.Immun.

11. Levenson V.I., Egorova T.P., Nartikiva et al. Lipid A          
    associated protein of Shigella: chemical and immunological     
    properties. In preparation.

PERSONAL DATA

    I arrived in the US this summer with a refugee status (employment 
authorized). I am married, have two sons who live separately.

PRESENT MAILING ADDRESS: 

2504 E. Stadium Rd, Charlottesville VA 22903. Tel: (804)293-7077.


REFERENCES:

Available upon request.


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