From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.influenzae genes galT, galK, galM and galR for
Date: 24 Jul 92 10:06:19 GMT
Distribution: bionet
Checksum: 40805     9

LOCUS       HEAGALTKMR   3943 bp ds-DNA             BCT       24-JUL-1992
DEFINITION  H.influenzae genes galT, galK, galM and galR for
            galactose-1-phosphate uridyltransferase, galactokinase, mutarotase
            and galactose repressor
ACCESSION   X65934
KEYWORDS    galK gene; galM gene; galR gene; galT gene; galactokinase;
            galactose repressor; galactose-1-phosphate uridyltransferase;
            mutarotase.
SOURCE      Haemophilus influenzae DNA.
  ORGANISM  Haemophilus influenzae
            Prokaryotae; Facultatively anaerobic gram-negative rods;
            Pasteurellaceae.
REFERENCE   1  (bases 1 to 3943)
  AUTHORS   Maskell,D.J., Szabo,M.J., Deadman,M. and Moxon,E.R.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: strain=RM.7004;
            From EMBL    entry HIGALTKMR;  dated 13-MAY-1992.
FEATURES             Location/Qualifiers
     CDS             complement(100..1098)
                     /product="galactose repressor"
                     /gene="galR"
                     /codon_start=1
                     /translation="MSTIRDVAKLANVSVATVSRVLNHSLSVSENTRLAVERAIAQLA
                     YQPNANAQALAVQNTDTIGVVVTDVTDAFFAILVKAVDKVAEAHQKTILIGIGYHHAE
                     KEREAINTLLRKRCSSLVVHSKALSDDELSHYLNTVQGMVIINRVIKGYEHRCVSLDN
                     QKGTYLATEMLIRYGHQHIAYIGSNHAIFDEVERRNGYLAALKDHNYLIIEQAITLNS
                     PDFEGGEKAMIDLLSYNKNLTAVVAYNDSMAAGAISVLNENNISVPSQFSIIGFDDMP
                     IARYLIPKLTTIRYPIDLMATYAAKLALSLTDEKIITPPVVQFNPTLVRRFSVESR"
     CDS             1306..2355
                     /product="galactose-1-phosphateuridyltransferase"
                     /gene="galT"
                     /codon_start=1
                     /translation="MTALFEPTEHPHRRYNPLIDQWVLVSPHRAKRPWQGQQEKVNEE
                     QKPSYDPTCYLCPSNKRITGELNPDYRKPYVFKNDFSALLEDTPAPEKSSDPLFQSSQ
                     ARGESRVICFSPDHSKTLPLLTALEIEEVIKVWQEQLRELGAKYQWVQIFENKGAAMG
                     CSNPHPHGQIWANSFLPNEVAREDRTQRDYLLKHGSVMLVDYVKRELALKERIVVETE
                     HWVALVPYWAVWPFETLLLPKTHVKRLTELSDEQSKDLAVILKKLTTKYDNLFETSFP
                     YSMGFHAAPFNGEDNEHWQLHAHFYPPLLRSATVRKFMVGYEMLGENQRDLTAEQAAD
                     RLRALSEVHYKERTK"
     CDS             2432..3586
                     /product="galactokinase"
                     /gene="galK"
                     /codon_start=1
                     /translation="MTPIQNAQQIFNRQHKNLPEITVYAPGRVNIIGEHTDYNDGFVM
                     PCAINFGTAVSGTKRDDHIWNVYAADLDETDEFSLNVEIPKSEHKWANYVRGVVKFIQ
                     ERYPHFQQGANLVISGNVPLSSGLSSSAALEVAVGKFCQQLGNLPLSHTDIALNGQKA
                     ENQFVGANCGNMDQLISALGQENHLLMIDCRSLETTPTPVPQDVAVIIVNSNVPHDLV
                     TGEYNTRRQQCEEAAKFFGVKALRDVSVEQFQKREAELTALSPLAAKRARHVVTENQR
                     VLDAVEALKNNDLTCLGKLMEASHDSMRDDFEITVPQIDYLVELVQLVIGKSGGTRMT
                     GGGFGGCIVALAPHDKVDAVRKIIADNYEKTTGLKETFYVCTASQGVRVI"
     CDS             3593..>3943
                     /product="mutarotase"
                     /gene="galM"
                     /codon_start=1
                     /translation="MMLEQTTFNAPDGAPYQLITLQNENGMRVQFMDWGATWLSCKIP
                     VNGTLREVLLGCKVENYPTHQSYLGASVGRYANRIANAQFELNGELIKLSSNQGKHQL
                     HGGEGFDKRRWKIQK"
BASE COUNT     1250 a    717 c    803 g   1173 t
ORIGIN
        1 gtacatcata aataaattat cgtaattaat ctatgagcaa atttgcaaaa atgaaaatga
       61 ttacataaaa aattatgaat ttgtgatcca tgtcacaaat tagcgcgatt ccaccgaaaa
      121 acggcgtacc aaagtagggt taaattgaac tactggaggt gtaattattt tctcgtcagt
      181 tagacttaat gctaatttag ccgcataagt tgccattaaa tcaataggat agcgaattgt
      241 ggttaatttt gggatcaaat aacgggcaat cggcatatca tcaaaaccaa taattgaaaa
      301 ttggcttggt acgctgatat tgttttcatt gagaactgaa atggctcccg ccgccattga
      361 atcgttataa gcaacgacag ccgtaagatt tttgttataa ctaagtaaat caatcattgc
      421 tttttcgccg ccttcaaagt ctgggctatt gagtgttatc gcctgttcaa tgatgagata
      481 attgtgatct tttaatgcgg caagataacc atttcttctt tcaacttcat caaaaatggc
      541 gtgatttgaa ccgatatatg caatatgttg atgcccataa cgaataagca tttccgtggc
      601 taaataagtg cctttttggt tatctaaact gacacaacga tgttcataac ctttaataac
      661 acggttaatg attaccattc cttgcacagt atttaaataa tggcttaatt catcatcaga
      721 taaggcttta gaatgtacaa caagagaact acaacgctta cgtaataagg tattaattgc
      781 ttcccgctct ttttccgcat gatgataacc aataccgata agaatcgttt tttgatgtgc
      841 ttctgctact ttatccaccg cttttactaa aattgcaaaa aaggcatccg tcacatcggt
      901 taccaccacg ccaattgtat cggtgttctg cacggcaagg gcttgagcat ttgcattagg
      961 ttgataagct aactgtgcaa tagctcgttc caccgcaagg cgtgtatttt cactaacaga
     1021 aagagagtga tttaatactc gggatacggt agcgacagat acattggcta atttagcgac
     1081 atctcgaata gtactcataa ctttttcctt gttataatct ataaatctta tattttgatc
     1141 ataaataatt tacgataaat tgaaagcggt tactttcata agtatgaact aaatcataaa
     1201 aaattttgct tattttctta ttttgtgaca aagatcacgg tttatttaca ataatttagt
     1261 ataaattaat gtaatcgctt acattgataa aaaacaggag tcaaaatgac cgcacttttt
     1321 gaacctacag aacatccaca tcgtcgctac aatccgttaa tcgatcaatg ggttttagtt
     1381 tcgccacatc gtgccaaacg cccgtggcaa gggcaacagg aaaaagtcaa tgaagaacaa
     1441 aaaccaagtt atgatccaac ttgttatctt tgcccgagta ataagcgtat tacaggggaa
     1501 ttaaatccag attatcgtaa accttatgtg tttaaaaatg atttttccgc gcttttagaa
     1561 gatacgccag cccctgaaaa atcctccgat cctcttttcc aaagttctca agctcgtggg
     1621 gaaagtcgag tcatttgttt ctctcccgat catagtaaaa cattgccatt attgaccgca
     1681 cttgagattg aagaagtgat taaagtatgg caggaacaac ttcgtgaact tggtgcgaaa
     1741 taccaatggg tgcaaatttt tgaaaacaaa ggggcggcaa tggggtgttc taacccacat
     1801 ccacatggtc aaatttgggc gaatagtttc ttgccaaatg aagttgctcg tgaagatcgt
     1861 acacaacgtg attatttgct aaaacatggc tcagtaatgt tggttgatta tgtaaaacga
     1921 gaattagcgt tgaaagaacg tattgtcgtt gaaactgaac attgggtcgc tttagtgcct
     1981 tattgggctg tttggccatt tgaaacattg cttttaccaa aaactcatgt aaaacgttta
     2041 actgaattaa gtgacgaaca atcaaaagat cttgcggtta ttttgaaaaa attgacgact
     2101 aaatacgaca atctctttga aacttctttc ccatattcaa tgggatttca tgcggcacca
     2161 tttaatggcg aagataacga acattggcag ctacatgctc atttttaccc tcctcttttg
     2221 cgttcagcaa ccgtgcgtaa atttatggtg gggtatgaaa tgttaggcga aaaccaacgc
     2281 gatttaacgg cggaacaggc tgcagatcga ttacgtgctt tgagtgaagt tcattataaa
     2341 gaaagaacta aataatatag tcagttcccc tctttagctt tagcaaagag gggtgcagat
     2401 cgagtataga tttaatataa aggatagaaa tatgacccca atccaaaatg ctcaacaaat
     2461 tttcaataga cagcataaaa atttgccaga aattaccgtc tatgcgcctg gcagagtaaa
     2521 tatcatcggc gaacataccg actacaacga cggctttgtt atgccttgcg caattaattt
     2581 tggtacggcc gtttctggta caaaacgaga tgatcatatt tggaatgttt atgcggcgga
     2641 tcttgatgaa actgatgaat tctctctcaa tgttgaaatt cctaagagtg aacacaaatg
     2701 ggccaattac gtgcgtgggg tggtaaaatt tatccaagaa cgttacccgc actttcaaca
     2761 aggtgcaaat ttagtgattt ctggtaatgt gccgctttct tcgggattaa gttcatctgc
     2821 agcgttagaa gttgcggtgg gtaaattctg ccaacaactt ggcaatttac cactttctca
     2881 cacggatatt gcattgaatg ggcaaaaagc ggaaaaccaa tttgttggcg caaattgtgg
     2941 caatatggat cagttaattt ctgcgcttgg gcaggaaaat catttactga tgatcgattg
     3001 tcgtagtctt gaaaccacgc caacaccagt gccacaagat gtcgccgtga ttattgtgaa
     3061 ttcaaacgta ccgcacgatt tagtaacagg cgaatacaat actcgccgtc agcaatgtga
     3121 agaggcagca aaattttttg gcgtgaaagc attacgagat gtttcagttg agcaattcca
     3181 aaaaagagaa gcggaattga ccgcactttc tccgttagca gcaaaacgcg ctcgtcatgt
     3241 cgtaacagaa aatcaacgag tacttgatgc agtagaagca ttgaagaaca atgatttgac
     3301 ttgtttaggt aaactaatgg aagcatctca cgattcaatg cgtgatgatt ttgaaatcac
     3361 cgtaccacaa attgattatt tagttgaatt ggttcaactt gttattggca aaagtggcgg
     3421 cacacgtatg acgggcggcg gttttggtgg ctgtattgtc gcacttgcac cgcatgataa
     3481 agtcgatgca gttcgtaaaa ttattgcgga taattacgag aaaacgactg gtttaaaaga
     3541 aactttttat gtgtgtaccg catcacaagg tgttcgagtg atttaagaga aaatgatgtt
     3601 agaacaaacc acttttaatg cgcctgatgg tgcaccttat cagcttataa ccctgcaaaa
     3661 tgaaaatggg atgcgtgttc aatttatgga ttggggcgca acttggcttt cttgtaaaat
     3721 accagtaaat ggcactttac gtgaggtttt attgggttgt aaggtagaga attaccccac
     3781 tcatcaaagc tatttaggcg caagcgtagg gcgttatgca aatcgtattg caaatgcaca
     3841 atttgaattg aatggcgaac ttattaaatt aagtagtaat caaggaaagc accagcttca
     3901 tggtggagag ggttttgata aacgtcgttg gaaaatccaa aag
//