From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens FACC mRNA from complementation group C (FA(C))
Date: 29 Dec 92 01:19:34 GMT
Distribution: bionet
Checksum: 37194 8

LOCUS       HUMFACC2     4485 bp ss-RNA             PRI       07-DEC-1992
DEFINITION  H.sapiens FACC mRNA from complementation group C (FA(C))
ACCESSION   X66894 X66184
KEYWORDS    DNA-repair disorder.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4485)
  AUTHORS   Buchwald,M.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 4485)
  AUTHORS   Strathdee,C.A., Gavish,H., Shannon,W.R. and Buchwald,M.
  TITLE     Cloning of cDNAs for Fanconi's anemia by functional complementation
  JOURNAL   Nature 356, 763-767 (1992)
  STANDARD  full automatic
REFERENCE   3  (bases 1 to 4485)
  AUTHORS   Strathdee,C.A., Duncan,A.M. and Buchwald,M.
  TITLE     evidence for at least four Fanconi anemia genes including FACC on
            chromosome 9
  JOURNAL   Nature Genet. 1, 196-198 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=adult; *source: tissue=lymphoid; *source: cell_line=
            hsc93; *source: sex=F;


               From EMBL    entry HSFACC2;  dated 26-JUN-1992.
FEATURES             Location/Qualifiers
     5'UTR           1..173
     3'UTR           1847..4444
     polyA_site      2214
     polyA_signal    2237..2242
     polyA_signal    3039..3044
     polyA_site      3152
     repeat_region   3273..3395
     polyA_signal    4362..4367
     polyA_site      4444
     CDS             174..1847
                     /codon_start=1
                     /translation="MAQDSVDLSCDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEF
                     LRKMYEALKEMDSNTVIERFPTIGQLLAKACWNPFILAYDESQKILIWCLCCLINKEP
                     QNSGQSKLNSWIQGVLSHILSALRFDKEVALFTQGLGYAPIDYYPGLLKNMVLSLASE
                     LRENHLNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPE
                     FFEAVNEAILLKKISLPMSAVVCLWLRHLPSLEKAMLHLFEKLISSERNCLRRIECFI
                     KDSSLPQAACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFVEALEKASKQLR
                     FALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQTHGSCGGPFE
                     SWFLFIHFGGWAEMVAEQLLMSAAEPPTALLWLLAFYYGPRDGRQRAQTMVQVKAVLG
                     HLLAMSRSSSLSAQDLQTVAGQGTDTDLRAPAQQLIRHLLLNFLLWAPGGHTIAWDVI
                     TLMAHTAEITHEIIGFLDQTLYRWNRLGIESPRSEKLARELLKELRTQV"
BASE COUNT     1051 a   1091 c   1167 g   1176 t
ORIGIN      
        1 gagcccccgg agaggcggga gcggtgttgg cgttttggtt ctttttgttc attgagcgca
       61 ggcagctatg tcttcttcaa aggagaggag caaagcttta atgtgtgccg accatttcct
      121 tcagtgctgg acaggctgct gtgaagggac atcacctttt cgctttttcc aagatggctc
      181 aagattcagt agatctttct tgtgattatc agttttggat gcagaagctt tctgtatggg
      241 atcaggcttc cactttggaa acccagcaag acacctgtct tcacgtggct cagttccagg
      301 agttcctaag gaagatgtat gaagccttga aagagatgga ttctaataca gtcattgaaa
      361 gattccccac aattggtcaa ctgttggcaa aagcttgttg gaatcctttt attttagcat
      421 atgatgaaag ccaaaaaatt ctaatatggt gcttatgttg tctaattaac aaagaaccac
      481 agaattctgg acaatcaaaa cttaactcct ggatacaggg tgtattatct catatacttt
      541 cagcactcag atttgataaa gaagttgctc ttttcactca aggtcttggg tatgcaccta
      601 tagattacta tcctggtttg cttaaaaata tggttttatc attagcgtct gaactcagag
      661 agaatcatct taatggattt aacactcaaa ggcgaatggc tcccgagcga gtggcgtccc
      721 tgtcacgagt ttgtgtccca cttattaccc tgacagatgt tgaccccctg gtggaggctc
      781 tcctcatctg tcatggacgt gaacctcagg aaatcctcca gccagagttc tttgaggctg
      841 taaacgaggc cattttgctg aagaagattt ctctccccat gtcagctgta gtctgcctct
      901 ggcttcggca ccttcccagc cttgaaaaag caatgctgca tctttttgaa aagctaatct
      961 ccagtgagag aaattgtctg agaaggatcg aatgctttat aaaagattca tcgctgcctc
     1021 aagcagcctg ccaccctgcc atattccggg ttgttgatga gatgttcagg tgtgcactcc
     1081 tggaaaccga tggggccctg gaaatcatag ccactattca ggtgtttacg cagtgctttg
     1141 tagaagctct ggagaaagca agcaagcagc tgcggtttgc actcaagacc tactttcctt
     1201 acacttctcc atctcttgcc atggtgctgc tgcaagaccc tcaagatatc cctcggggac
     1261 actggctcca gacactgaag catatttctg aactgctcag agaagcagtt gaagaccaga
     1321 ctcatgggtc ctgcggaggt ccctttgaga gctggttcct gttcattcac ttcggaggat
     1381 gggctgagat ggtggcagag caattactga tgtcggcagc cgaacccccc acggccctgc
     1441 tgtggctctt ggccttctac tacggccccc gtgatgggag gcagagagca cagactatgg
     1501 tccaggtgaa ggccgtgctg ggccacctcc tggcaatgtc cagaagcagc agcctctcag
     1561 cccaggacct gcagacggta gcaggacagg gcacagacac agacctcaga gctcctgcac
     1621 aacagctgat caggcacctt ctcctcaact tcctgctctg ggctcctgga ggccacacga
     1681 tcgcctggga tgtcatcacc ctgatggctc acactgctga gataactcac gagatcattg
     1741 gctttcttga ccagaccttg tacagatgga atcgtcttgg cattgaaagc cctagatcag
     1801 aaaaactggc ccgagagctc cttaaagagc tgcgaactca agtctagaag gcacgcaggc
     1861 cgtgtgggtg cccggcgtga gggatcaggc tcgccagggc cacaggacag gtgatgacct
     1921 gtggccacgc atttgtggag taagtgccct cgctgggctg tgagaatgag ctgtacacat
     1981 cttgggacaa tctgctagta tctattttac aaaatgcaga gccaggtccc tcagcccaga
     2041 ctcagtcaga catgttcact aatgactcaa gtgagcttcg gtactcctgg tgcccgcccg
     2101 gccagaccgt cagcttgata attactaaag caaaggcctg ggtgggagaa caggtttcta
     2161 gtttttaccc aagtcaagct gcacatctat tatttaaaaa ttcaaagtct tagaaccaag
     2221 aatttggtca tgaaccatta aagaatttag agagaactta gctcttttta gactcttttt
     2281 aggagtcagg gatctgggat aaagccacac tgtcttgctg tatggagaaa ttcttcaagg
     2341 ggagtcaggg tccctcaggc ttcccttgtg tctccctgga cctgcctgac aggccacagg
     2401 agcagacagc acacccaagc ccgggcctcc ggcacactct ttccactctg tatttgctaa
     2461 atgatgctaa ctgctaccaa aaggcccttg ggacatcaga ggagccggca gcgaaggtag
     2521 aggatgtgtt ccagaaacat tagaaggcag gattaattca gttagttagt ctcttgttaa
     2581 atggaaatgg gaattggaaa ttcctgataa agaattggcc tggctgggtg cagtggctca
     2641 cacctgtgat cccagcactt tgggaggcca aggcaggggg attacttcag cccaggagtt
     2701 ccagactgcc tggctaacat ggcaataccc tatctctact aaaaatacaa aaattatcgg
     2761 ggtgcaatgg catgcatctg taacccagct attcaagagg ctgaggcatg aggatctctt
     2821 gaacccggga ggtgggagtt gtagtgagcc gagatcatga cactgcactc cagcctgggc
     2881 aacagagcga gaccatctct taaaaaaagg cattgttagt gtaactcaag gttaacattt
     2941 atttcatgtc agtacagggt gctttttcct ttcagggaca ttctggaatt gtattggttg
     3001 tacattcttt tgtgtctatt ctgtttgtca agtgagtcaa gacttgcttt tgtccatttt
     3061 gatttgtgtg tattagtctg agtcttggct ccgttttgag gtatgagcaa agttttgctg
     3121 gatagagtta acctttaggg aaattcctta ttttggtatg tggcaatgct aatagatcca
     3181 ctgaagatct ggaaaattcc aggaactttt tcacctgagc ctttcttctg agaaatgctg
     3241 cagtcagaag ggtgtgctgg taaagtattt tggtggcagc tgccatcatg gtcattgcct
     3301 tcatataaca tgcttcgtgc tcatggtcat tgccttcata taacatgctt cgtgccatca
     3361 tgatccttgc cttcatataa caaacatgct tcgtcagagg tgttggggtt gaaaaaggag
     3421 ctgcatgctt cactggagtt gagggcctct cctgtctgac tttaagccag aacttgtggc
     3481 tgggccatgg aagctgtgac tcctctgtgg acatggtggc agcagggaac ccctagagag
     3541 aggggccact gggaccaggc ctcctgttgt ggagggactc ctgggacagt cctccaccct
     3601 gtcctgtggt cctgtgtaca gggttggcct cttcctcctc ccctgccagg cctctgccca
     3661 tgccccttcc ttccttctcc tgggactggt gaagctaggc atctggaaga cttcttccta
     3721 gcctggaagc cctgacctcg gcccatctgc agaatctccc agttccttca cagctgccga
     3781 gtcctctcac gggtgcggtg gaggcggcct tgcggtggtg ctttctgggc agccaggggt
     3841 tcctgggtgg gaggactgtc cctctgggga cgtggcactg aagtgcctgc tggcttcatg
     3901 tggccctttg ccctttccca gcctgagaga tgctcaaagg tggggagctg ggggagccac
     3961 ccctcggcca ttccctccac ctccaagaca ggtggcggcc gggcaggcac tcttaagccc
     4021 acctccccct cttgttgcct tcgatttcgg caaagcctgg gcaggtgcca ccgggaagga
     4081 atggcatcga gatgctgggc ggggacgcgg cgtggcgagg gggcttgacg gcgttggcgg
     4141 ggctgggcac aggggcagcc gcagggaggc agggatggca aggcgtgaag ccaccctgga
     4201 aggaactgga ccaaggtctt cagaggtgcg acagggtctg gaatctgacc ttactctagc
     4261 aggagttttt gtagactctc cctgatagtt tagtttttga taaagcatgc tggtaaaacc
     4321 actaccctca gagagagcca aaaatacaga agaggcggag agcgcccctc caaccaggct
     4381 gttattcccc tggactccgt gacatctgtg gaatttttta gctctttaaa atctgtaatt
     4441 tgttgtctat tttttcattc taaataaaac ttcagtttgc accta
//