From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Drosophila melanogaster brain-specific-homeobox protein gene,
Date: 21 Dec 92 20:40:47 GMT
Distribution: bionet
Checksum: 47472 6

LOCUS       DROBSHHB     2672 bp ds-DNA             INV       17-NOV-1992
DEFINITION  Drosophila melanogaster brain-specific-homeobox protein gene,
            complete cds.
ACCESSION   L06475
KEYWORDS    homeobox protein.
SOURCE      Drosophila melanogaster (strain Oregon R) DNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 2672)
  AUTHORS   Jones,B. and McGinnis,W.
  TITLE     A new Drosophila homeobox gene, bsh, is expressed in a subset of
            brain cells during embryogenesis
  JOURNAL   Development (1993) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     mRNA            join(88..311,782..1056,1442..1743,2162..>2672)
                     /gene="bsh"
     5'UTR           88..294
                     /gene="bsh"
     exon            88..311
                     /number=1
                     /gene="bsh"
                     /label=exon1
     intron          312..781
                     /number=1
                     /gene="bsh"
     exon            782..1056
                     /number=2
                     /gene="bsh"
                     /label=exon2
     intron          1057..1441
                     /number=2
                     /gene="bsh"
     exon            1442..1743
                     /number=3
                     /gene="bsh"
                     /label=exon3
     variation       replace(1554,"")
                     /note="'t' in variation"
     intron          1744..2161
                     /number=3
                     /gene="bsh"
     exon            2162..>2672
                     /number=4
                     /gene="bsh"
                     /label=exon4
     variation       replace(2217,"")
                     /note="'a' in variation"
     3'UTR           2249..>2672
     CDS             join(295..311,782..1056,1442..1743,2162..2248)
                     /function="'transcription factor'"
                     /product="brain-specific homeobox protein"
                     /codon_start=1
                     /translation="MHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQP
                     PPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFG
                     GAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSPP
                     ERVELATALGLSETQVKTWFQNRRMKHKKQLAGATMPMSPSTSHAANRASSRARPPPP
                     PGTPSTAN"
BASE COUNT      833 a    607 c    555 g    677 t
ORIGIN      
        1 acgccgtttc catcgagcac atattgttca aactaaatag tgccagcaat aacaatatag
       61 tagtgatacc aagcatcgcc gcaaacacca acaactacgc gccaaagagc agcagaaacg
      121 cggtgaaaag tgccagaagc gcatttgccc acgacaataa tccgcacaaa catccgtcgc
      181 aacattcgca tccgccgcag tcacatccgc cggcgtccgc atcgcatccg cgacggctac
      241 tgcccgcagc aaccaggctg cgtcgggtta cgctggcgag gatacggcaa gtccatgcac
      301 agcactccac ggttggtttc cgaattccat ggcctaatac tactgcagtg aaattttagt
      361 ttaaaaaact ttaattttaa gccaatataa ttgcatagaa aagtgaaaaa aagtaattaa
      421 aataaaaaaa aaataaataa aaaataagct aatattaaca aagtgaattt ataaaagaat
      481 aagaagtaaa catcaaacat caaatacgat agatagtcac accttcttga agacaaatat
      541 tttggaatag catacacctt taaaatctta ctttggatta tgttctttta aattatagaa
      601 tattttttgt aagaaaaatg atattttgga aacatagaaa tcaggcttac cataaagctt
      661 aatgtatctg ggaatatata tttgtattta agcatattag cataaaaatc actattggac
      721 ataaagagaa tagtttacat cgaaatccaa tagaccccta attgaaccac ttgcttcgta
      781 ggtccaacca ccactcgcga catggaactt cccactacaa cggagatcag atttcgcagc
      841 agttgggatc tggagcagca caacatccgc cggtgcccac gactcaacct caacctccgc
      901 ctccgccgcc cctgaatgga ggtagtggtg catccaatgg agtactctat ccgaatgcac
      961 cctacaccga tcacggattt cttcaaatga ccctcggata tctctcgccg tcgtcgggca
     1021 cctacaagtc cgtggatccc tattttctat cacaaggtga gttaatgctc gatattacag
     1081 agatatcctc ctagatgatt ctgatttgta ctagtacata caaacatgtt ggtaataagt
     1141 taaagtcgaa ctcatagaaa ttaaaagtca attctagcat gagtttagct aatcaaaatg
     1201 aagttggaca tattctcatt aaaaagccag caacatttaa tttaacattt agaacttttt
     1261 cgaaatgaaa cccaaattag taggacaact gatgttgaag tgcagttttt gttgccacat
     1321 agcttcattt agggcactaa aactgcgaaa tattcggtgt aaatgaccat caacaccgaa
     1381 agttttcatt tgttccaact ataacgaagt taaccaaatt ttgcatcctt tgccctttca
     1441 gccagcctgt tcgggggagc gcccttcttc ggagcgcctg gctgtgtgcc ggaactggcc
     1501 ctcggactgg gaatgggcgt gaatgccctg cgccactgcc gccggaggaa ggcccgcacg
     1561 gtgttcagtg atccgcagct gtccggtctg gaaaagcggt tcgagggaca gcgatacctg
     1621 tcaccgccgg agcgtgtgga gctggccacc gccttgggac tcagcgagac gcaggtgaag
     1681 acctggttcc agaaccgccg catgaagcac aaaaagcagc tcgccggcgc gacaatgcca
     1741 atggtgtgta cattgattca taatcataaa ttattatgag caaattaaat attacgaaat
     1801 ttataatact caaatcaagt tatttaatat tcaaaccttt tctgggctgt taagaacaac
     1861 tagagcgaaa aagagttgcc taagttttcc agcttttaga caatgcaata tttgagttag
     1921 caattgaaat tgtcaaaagg catttcgagc aggagtggtc agcggttttc aaattggtca
     1981 caaagcacca aaaactagac cactggagtg agtagtttct ttgaggaact tttggactat
     2041 caattagacc ttttggcttt tagccggctc cttgtgatgc aaaaagtttt gctcaagttt
     2101 caacgcaaat caaattagtt ctaaattttg tggaaatttc tttgactctt ccatgccgca
     2161 gagcccgtcg acttctcacg cagcgaaccg ggcaagcagc cgggcgaggc cacctcctcc
     2221 tccggggact ccaagcacgg caaactgaat cccggatctg tcggcggcac acccactcag
     2281 ccgacgagcg agcagcagct gcagatgtgc ctgatgcagc agggttactc cacggatgac
     2341 tactccgatc tggaggcgga cagtggcgac gaggacaact ccagcgacgt ggacatcgtc
     2401 ggcgatgcga aactctacca gttaacatag acagttcgat cgggatgtgg acctggatcc
     2461 taaagtagta aagttttcgg tgtttcagtt gggggaaata caactaaaag agattttcaa
     2521 atcaaaaaat atcagtttct tttactaaat gacttttcta ttagacaagc acagaagtta
     2581 caaaacaaca catatcttat cagcgcgagc atggatatac cattttgaaa atatctatta
     2641 ttacgattta gtacgaacta tagttcctta gg
//