From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: plc-21=phospholipase C (PLC) gene [Drosophila, mRNA, 5586 nt]
Date: 3 Jan 93 22:09:13 GMT
Distribution: bionet
Checksum: 37068 11

LOCUS       S39797       5586 bp    mRNA            INV       21-DEC-1992
DEFINITION  plc-21=phospholipase C (PLC) gene [Drosophila, mRNA, 5586 nt]
ACCESSION   S39797 M60452
KEYWORDS    .
SOURCE      Drosophila
  ORGANISM  Drosophila
            Unclassified.
REFERENCE   1  (bases 1 to 5586)
  AUTHORS   Shortridge,R.D., Yoon,J., Lending,C.R., Bloomquist,B.T.,
            Perdew,M.H. and Pak,W.L.
  TITLE     A Drosophila phospholipase C gene that is expressed in the central
            nervous system.
  JOURNAL   J. Biol. Chem. 266, 12474-12480 (1991)
  STANDARD  full automatic
COMMENT     This entry [NCBI gibbsq 39797] was created by the journal scanning
            component of NCBI/GenBank at the National Library of Medicine.
            This sequence comes from Fig. 3.  Map location: 21C.
FEATURES             Location/Qualifiers
     CDS             825..4739
                     /note="Description: phospholipase C (PLC) gene;
                     phosphatidylinositol-specific phospholipase C;  For the
                     protein sequence (NCBI gibbsq 39801):  This sequence comes
                     from Fig. 3.
                     Author-given protein sequence is in conflict with the
                     conceptual translation"
                     /gene="plc-21"
                     /product="PI-PIC"
                     /codon_start=1
                     /translation="MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVD
                     AKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVT
                     VCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQ
                     VDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYK
                     YLTQRSEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKEL
                     IQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHN
                     TYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVL
                     EAIAESAFKTSEYPVILSFENHCNPRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMD
                     LPPPAMLRRKIIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVA
                     LSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSS
                     EDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCY
                     EMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVA
                     LNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSIT
                     VLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVL
                     PELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKD
                     YVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSCGQKKELR
                     PVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVST
                     SIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQK
                     SSPLEGKKPKFAITNKLVKRLSNKSLEPGVEIPACPLDLGDSSEESAAADAGEDLAGG
                     SSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASL
                     DKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAERVRLKQTF
                     DRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTG
                     SGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT"
BASE COUNT     1538 a   1372 c   1404 g   1272 t
ORIGIN      
        1 gagaacgaac ggagaccaaa agtcgcacgg cagcgatata agcgggtctt ataagcctaa
       61 tctaaatcta aactgggaga acaggaccta tgtatgtcct gctatccaat tcgtctatca
      121 ctgctcttca acgtcgtcgc gttttttggg ctttcgggtg tatttttttg ttttgaattg
      181 ttgacacatc tccgggacgt ttcatcgttt tggattgtaa ttaggcgtgc aagtggaaaa
      241 gataataaat caaagccaat gtgcagcgtg agagtaacga aaaaaaaaac aaaacaatcg
      301 cagcgtgaga ctttgctttt tgttgtctat tgctaagtga tgctgcagca acaatagtaa
      361 ccaaagcatc aagaacatca ataagagctc ccgcaaaaat tcgccgaacc taaacttatt
      421 gcaaaacaac aagaattgtc gtaatacggt tgttttttct gcattattac ttcataacag
      481 agtgtcgctc tctcgctcgc tccggaaaac gtccgctttt ggggttctct ctcgctcaga
      541 aaacagccag aacttttaat cagtcccaga atgcagtcca aagagctcgc atgcggtgca
      601 aagtcaatac cgctctaacg tgtccaggac catgtcgatg attcggatac caaccaggac
      661 tatggcgtca tttgtatgcg gtgtggctat tctgcgacaa ctaagggaaa ggaaatgagg
      721 agccgcggct aatccaagaa tcgcacagaa agtaaacaga aagcgttcat cagtgggtca
      781 gtagcagccc gtaaacgaga ttttaaaccc aaaaatttgt gaggatgatg agcgccggag
      841 gaacctacat ctccaccgcc agcgtggagg tgccacaagc tctgcaagat ggcgagaagt
      901 tcattcgatg ggatgatgac tcgggcactg gaacaccggt tacaatgcgc gtcgatgcca
      961 agggcttctt cctctactgg gtcgaccaga acaacgagct ggatatcctt gatatagcca
     1021 ccatacgcga cgttcgcaca ggacagtacg ctaagcgacc aaaggacaac aagctgcgcc
     1081 agattgtgac gctgggcccc caggacacgc tcgaggagaa gacagtgacg gtatgccacg
     1141 gctcggactt cgtcaacatg acgttcgtca acttctgctg cacccggcgg gacatagccc
     1201 agctctggac cgacggactc atcaagttgg cctacagctt ggcccagctc aatggctcgg
     1261 cgattatgtt cctgcagaag gcccatacca aactgtgtct ccaggtggac aaaagcggcc
     1321 gcataccagt gaaaaacatc ataaaacttt ttgcccaaaa caaggaggat cgcaaacgtg
     1381 tcgagaaggc gctggacgtg accggtttgc cgtcgggaaa ggtcgatagc atatcggtgt
     1441 ccaaatttca attcgaggac ttttacaatt tgtacaaata tctcacgcag cgttcggagg
     1501 tagaacgcct ctttgacagc atcgttggca actcgaagcg caagtgcatg tccatcgctc
     1561 aactggtgga gttcctgaac aagacacagc gtgatccccg cctgaacgag atcctctacc
     1621 cttatgcgaa tcccgcccgc gccaaggagc tcatccagca atatgagccc aacaagttca
     1681 acgcgcaaaa gggccaactc agcctggatg gctttttgag gtacttaatg ggcgacgaca
     1741 atcccatcat ggcgcccagc aagctcgatc tctgcgatga catggaccag ccgatgtcgc
     1801 actacttcat caactcctcg cataacacct acttgacggg acaccagctg accggcaagt
     1861 cgtccgtcga gatttacagg cagtgtctcc tggcgggatg cagatgcgtt gagctcgact
     1921 tctggaacgg acgcaccgag gagccagtca ttgtccacgg ctatacgttc gtgcccgaga
     1981 tatttgccaa ggacgtgctg gaggccatcg cagagagtgc atttaaaaca tccgaatacc
     2041 ctgtgatatt gagctttgag aatcactgca accctaggca acaggcgaaa attgccaact
     2101 attgtcgcga aatatttggc gatatgctgc tcgataagcc tctagactct catccgctgg
     2161 agccgaacat ggacttgcca ccgccggcga tgctgcgccg caagattata atcaagaaca
     2221 agaagaagca tcaccaccac catcaccatc atcaccacaa aaagccagcg caggtgggca
     2281 cgccggcagc caacaacaaa ctgactacag cgaattcagt ggatgccaag gcggcgcaac
     2341 aagtcgcttt gtcggcctcg catgaggatg ggggcgtgac caggagcacc gccaacggtg
     2401 acgttgccac tggaacagga accggaagtg ctgctgggac agcaggacac gcgccgccgt
     2461 tgcaacaaat ccgccaaagc tccaaagaca gcactggatc ctccgattcg gacagctctt
     2521 cggaggatga atccctgcct aacaccacgc ccaatttgcc cagcggcaac gaacctccgc
     2581 cagaaaaggc tcaaaaggaa acggaggcgg gagcagagat ttcagctttg gtcaactatg
     2641 ttcagcccat ccattttagc tcttttgaga atgcggaaaa aaagaatcga tgctacgaaa
     2701 tgtcttcgtt tgatgaaaaa caggcgacaa cattattgaa ggagcgaccg attgaatttg
     2761 tgaactacaa caaacaccaa ttatctcgtg tctatccggc gggcactcgc tttgatagct
     2821 ccaactttat gccgcagttg ttctggaatg ccggatgtca gctcgtggca cttaacttcc
     2881 aaaccctcga tctggccatg caactcaact tggggatctt tgagtataac gctcggtccg
     2941 gttatctact taagccggag tttatgcgcc gatcagatcg cagattggat cccttcgcgg
     3001 aaagcactgt ggatggcatc atagcaggca cagtatcaat cacggttcta tctggtcagt
     3061 ttctcacgga taagagggcg aacacttttg tggaagttga tatgtacggt ttgccagcgg
     3121 acacggtgag aaagaagttt cgcaccaaga cagtgcggga taatggaatg aatccccttt
     3181 atgacgagga gccgttcgtg tttaagaagg tggttctccc cgagttggcg agcattcgaa
     3241 ttgcagcata tgaagagggt ggcaaactca ttggtcaccg cgttttgccc gtaatcggtc
     3301 tttgccctgg ttaccgacat gtgaatctcc gatctgaagt gggtcaacca atagcccttg
     3361 cctctctttt cctgtgcgtg gtggtcaagg attatgtacc cgatgatctt tccaatttcg
     3421 cagaggcgct agctaaccct attaaatacc aaagtgagct agagaagcgc gatattcaac
     3481 tatctgtttt gaccgacgaa gccgaagcgc tgggcagtgc ggacgaggat ctctccaagt
     3541 cgtgtggcca aaaaaaggag ctgcgtccgg ttgaatcgct tgcgacttcg ccgaagcata
     3601 ggccgagcat ctcggccgcc gcagcaatga gtgttgacgt taccgtggat cggaccgatg
     3661 gcggaagggg agaagatagc atctctattg tagcaccctc aatacagcat cagcactctc
     3721 tagaccagtc cgtaagcacc tccatccgac aggtggagtc ctcgcagttt gatgtcgatc
     3781 ttgtgttggc ggagccgctg gaaaagatat tggatcacaa gtccgtcaag gaaaagcgtc
     3841 tcgagatgga aaagaagctg gagtcactgc gaaagaagca tgacaaggaa aagattaaga
     3901 tcgccggcca gaaatccagt ccgctagagg gcaagaagcc gaagtttgcc atcacgaata
     3961 agctggtgaa gcggctaagc aacaagagtc tcgagcctgg tgtagagatc cccgcctgcc
     4021 ctctggatct gggcgatagc agcgaggaga gtgcagccgc ggatgccggt gaggacttag
     4081 ccggtgggag cagcagtctg gatggcagaa ctcaagagtc gcgattacgc agtgcctgcc
     4141 gggagtacac ttcccagtac cgtgagctgc aggagaagta ccatgaggca atttacagtg
     4201 cagccgagaa ggtgctgaag acatcgcaaa ctgggcaaac aaagcagtta aaagcatctc
     4261 tggacaaggt cactggagag gttatgcacc agctgcagga ggcccgccgc aacgaggtta
     4321 agaatctggc caccgtgcac cgggatcgtg atgagctgat cagaatgaaa cgcgaggtgg
     4381 caagctccgt tgtggaacgt ggcgtagctg aacgtgtgcg gctgaagcag acctttgacc
     4441 ggagaacgga tgaacttcag aagcagcacg actcagtgcg caatgccctg gcagagcacc
     4501 gctccaaggc tcgtcaaatt ctcgacaagg aggcagaatc gcgaagctgt gtatccagca
     4561 atggcttctt ggtcctcttc catggacctc atcaccatgg ctgtacgggc tccggctcgt
     4621 cagccctttc aggcaataat ctcactctaa atctggacgc gggggctgcc ggtagtcatt
     4681 cagccatttc gccggcaaag tcgcacaaca gcatcgcagc agcggccgag atgaagacgt
     4741 aaatgggcca cgccgtatag gtttttctcc ccgcccaaat tatccctagg attaattgtg
     4801 gttctaaagt tgttagtctt cagtatttac agcagaaaca taggaatgaa aagtcttcgt
     4861 agtatataag cagtggagga gtagtcccta tcctcccaca cctatttgac gggaactgac
     4921 ctcgattaga tcttaggacc tttgacccta ggcattgtaa atcccactgc taaggggaat
     4981 ccaagcaaac acgttttcta actgaacaaa ctagatgtaa atctatcgca tgtatgatgt
     5041 acttgtagcg taactgttga cgtatccgta ctttacagta ctttatctgt atactgaacg
     5101 gtgtatttct atggtgttaa tggaggttga tccatcacac tcccgtcaaa ccgtacggtt
     5161 tcttcctatt cgaacttcgc tgaaactctg agtgtctaat taagcaagca aatgtaacag
     5221 aagcagaaaa taagtataat ttatttgtct atacgaagga gactgagtgc tccatttgtc
     5281 taatgctaat tgtggttgtg tgtattttac atcagtttta atcgatataa tttatacaat
     5341 tagtttaagc ctctcacaca aactgtggat tgaatctcgt gcgcacacaa ggcggatgct
     5401 agagcggatg ccaaagcaca agtctaggcc aacaattagt catttatttc tcggttggtt
     5461 gctatttatt cttgatttag tcactattct tacgtttacc tagtcgttac aaagctccaa
     5521 taaaattcta tacggattgt ttttccccac ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     5581 aaaaaa
//