From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens Ig germline lambda-chain gene variable region
Date: 6 Nov 92 18:06:52 GMT
Distribution: bionet
Checksum: 44728 4

LOCUS       HUMIGLVD      650 bp ds-DNA             PRI       28-OCT-1992
DEFINITION  Homo sapiens Ig germline lambda-chain gene variable region
            retinoblastoma subgroup I (IGLV), 5' end cds.
ACCESSION   M94112
KEYWORDS    germline; immunoglobulin light chain; lambda immunoglobulin;
            variable region; variable region subgroup VL-I.
SOURCE      Homo sapiens (library: EMBL-3) retinoblastoma DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Daley,D.M., Olee,T., Peng,H.-q., Soto-Gil,R.W., Chen,P.P. and
            Siminovitch,K.A.
  TITLE     Molecular characterization of the human immunoglobulin V lambda-I
            germline gene repertoire
  JOURNAL   Mol. Immunol. 29, 1031-1042 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     misc_feature    38..624
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="IGLV"
     sig_peptide     join(276..286,120..165)
                     /pseudo
                     /gene="IGLV"
                     /note="putative"
                     /codon_start=1
                     /citation=[1]
     exon            <120..165
                     /number=X
                     /gene="IGLV"
     CDS             join(120..165,276..583)
                     /pseudo
                     /standard_name="Humlv101"
                     /product="immunoglobulin lambda-I V-region"
                     /gene="IGLV"
                     /codon_start=1
                     /partial
     TATA_signal     38..44
                     /gene="IGLV"
     intron          166..275
                     /gene="IGLV"
     exon            276..583
                     /number=X+1
                     /gene="IGLV"
     mat_peptide     287..583
                     /pseudo
                     /standard_name="Humlv101"
                     /product="immunoglobulin lambda-I V-region"
                     /gene="IGLV"
                     /note="putative"
                     /codon_start=1
                     /citation=[1]
     misc_signal     586..592
                     /standard_name="heptamer recombination signal"
                     /note="heptamer recombination signal"
                     /gene="IGLV"
                     /note="putative"
                     /citation=[1]
     misc_signal     616..624
                     /standard_name="nonamer recombination signal"
                     /note="nonamer recombination signal"
                     /gene="IGLV"
                     /note="putative"
                     /citation=[1]
BASE COUNT      135 a    193 c    181 g    141 t
ORIGIN      
        1 ggtcagctgc acaaggtagg gattcccact ctcagagtat gaagaggggc agggagagat
       61 ttggggaagc tctgcttcag ctgtgggcac aggaggcagc actcaggaca atctccagca
      121 tggcctggtc tcctctcctc ctcactctcc tcgctcactg cacaggtgac tggatacaga
      181 tcgaggggag ggtccctggg aagcctatgg attcttgctt tctcctcttg tctctagaag
      241 cagaatcatg atgcctgtgt ctctcccact tccagggtcc tgggcccagt ctgtgctgac
      301 gcagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct gcactgggag
      361 cagctccaac attggggcgg gttatgttgt acattggtac cagcagcttc caggaacagc
      421 ccccaaactc ctcatctatg gtaacagcaa tcggccctca ggggtccctg accaattctc
      481 tggctccaag tctggcacct cagcctccct ggccatcact ggactccagt ctgaggatga
      541 ggctgattat tactgcaaag catgggataa cagcctgaat gctcacacag tgctccaggc
      601 ccagggggag gtgagagaag aacccccttc ctcctctacc aggagggtga
//