From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens porin (por) mRNA, complete cds and truncated cds.
Date: 26 Jan 93 05:48:08 GMT
Distribution: bionet
Checksum: 52310 5

LOCUS       HUMPORIN     1464 bp ss-mRNA            PRI       25-JAN-1993
DEFINITION  Homo sapiens porin (por) mRNA, complete cds and truncated cds.
ACCESSION   L08666
KEYWORDS    VDAC; mitochondria; porin.
SOURCE      Homo sapiens blood cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Ha,H., Hajek,P., Bedwell,D.M. and Burrows,P.D.
  TITLE     A mitochondrial porin cDNA predicts the existence of multiple human
            porins
  JOURNAL   Unpublished (1993)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..247
                     /gene="por"
     3'UTR           1292..1464
                     /gene="por"
     polyA_site      1464
                     /gene="por"
     CDS             248..1291
                     /function="mitochondrial pore-forming protein"
                     /standard_name="VDAC"
                     /gene="por"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
                     /note="Met at bp 326 also used as initiation codon in
                     vitro"
                     /product="porin"
                     /codon_start=1
                     /translation="MSWCNELRLPALKQHSIGRGLESHITMCIPPSYADLGKAARDIF
                     NKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLETKYKWCEYGLTFTEKWN
                     TDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDFDFA
                     GPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGG
                     SIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQT
                     LRPGVKLTLSALVDGKSINAGGHKVGSPWSWRLNPAERNLWEWISEDLALIYFHCDQQ
                     QAFFPPEDDQNKG"
     CDS             326..1291
                     /gene="por"
                     /evidence="EXPERIMENTAL"
                     /citation=[1]
                     /note="Met at bp 248 also used as initiation codon in
                     vitro"
                     /product="porin"
                     /codon_start=1
                     /translation="MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTS
                     GSSNTDTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTT
                     FSPNTGKKSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSA
                     KSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTR
                     FGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVG
                     SPWSWRLNPAERNLWEWISEDLALIYFHCDQQQAFFPPEDDQNKG"
BASE COUNT      397 a    315 c    356 g    396 t
ORIGIN      
        1 gctgctggag ctgcagcccg accgcgagcg tgccaagcgg cttcagcagc tagcggacgt
       61 ggcggcggcc cccctcagga caccaccaga ttcccctctt cccgcggcct cgccatggcg
      121 acccacggac agacttgcgc gcgtcgatcg gatcaatcac ttttctagag gaagtagcag
      181 tccctcttgt gagagcgcaa ggtcattact tgtgctccta agggcgtgga cgtgctttgt
      241 ggaatgaatg agctggtgta atgagctcag attgcctgcc cttaagcagc acagcattgg
      301 ccgaggactt gagagtcaca ttacaatgtg tattcctcca tcatatgctg accttggcaa
      361 agctgccaga gatattttca acaaaggatt tggttttggg ttggtgaaac tggatgtgaa
      421 aacaaagtct tgcagtggcg tggaattttc aacgtccggt tcatctaata cagacactgg
      481 taaagttact gggaccttgg agaccaaata caagtggtgt gagtatggtc tgactttcac
      541 agaaaagtgg aacactgata acactctggg aacagaaatc gcaattgaag accagatttg
      601 tcaaggtttg aaactgacat ttgatactac cttctcacca aacacaggaa agaaaagtgg
      661 taaaatcaag tcttcttaca agagggagtg tataaacctt ggttgtgatg ttgactttga
      721 ttttgctgga cctgcaatcc atggttcagc tgtctttggt tatgagggct ggcttgctgg
      781 ctaccagatg acctttgaca gtgccaaatc aaagctgaca aggaataact ttgcagtggg
      841 ctacaggact ggggacttcc agctacacac taatgtcaat gatgggacag aatttggagg
      901 atcaatttat cagaaagttt gtgaagatct tgacacttca gtaaaccttg cttggacatc
      961 aggtaccaac tgcactcgtt ttggcattgc agctaaatat cagttggatc ccactgcttc
     1021 catttctgca aaagtcaaca actctagctt aattggagta ggctatactc agactctgag
     1081 gcctggtgtg aagcttacac tctctgctct ggtagatggg aagagcatta atgctggagg
     1141 ccacaaggtt ggctcgccct ggagttggag gcttaatcca gctgaaagaa acctttggga
     1201 atggatatca gaagatttgg ccttaatata tttccattgt gaccagcagc aggctttttt
     1261 ccccccagaa gatgatcaaa acaaaggatg atctcaacaa gagctgtatt ttaagtattt
     1321 agacagttct ttgttagctg gtttctagtt ggttatctag ttaccaatgc tgcagtcctg
     1381 cagtcaccta tacattattt aaatgtattt aactgttaaa tgcgctaccc accaataatg
     1441 aaatagacct ttatgaaaac tgtg
//