HDTenEightyP/NetNews huggingface dataset:
From: saj@chinet.chi.il.us (Stephen Jacobs)
Subject: Re: Azide Chemistry
Summary: Straightforward, if weird
Organization: Chinet - Public Access UNIX
Date: Fri, 28 Aug 1992 14:10:40 GMT

In article <awcnv#+.ladasky@netcom.com> ladasky@netcom.com (John J. Ladasky II) writes:
>	O.K., I've got an o-chem question.
>
>	The paper, "Selective covalent binging of an Ethidium Analog to
>Mitochondial DNA with Production of Petite Mutants in Yeast by Photoaffin-
>ity Labeling" (Hixon SC et. al., J. Mol. Biol 92:319-329 [1975]), contains
>a reference to a reaction that is not covered in my o-chem references.
>
>	A primary amine (alpha to a benzene ring, if that matters) is
>converted to an azide by suspension of the reactant in concentrated HCl 
>and sodium azide at 5C, followed by dropwise addition of sodium nitrite.
>Does anyone know of a general refernce to this reaction?  In particular, 
>I'm interested to know what side reactions might occur - will the azide 
>attack alkylated tertiary amines?
>
I've never seen this one before, and I'd be reluctant to try it, but what's
going on is clear.  The primary amine is being diazotized.  Being aliphatic,
it promptly decomposes to the carbonium ion; being benzylic (and that is
important here) it lasts long enough to react with something external--in
this case, to combine with the azide ions in the solution.  Neat, in a way.

But hydrazoic acid is volatile, explosive, lethal in concentrations
comparable to the concentrations at which HCN is lethal, and causes distress-
ing circulatory problems (including monumental headaches) at low concentrations.

I just wouldn't want to do it this way.  Could you maybe displace a benzylic
chloride or tosylate with azide in DMSO or liquid ammonia?  Not totally safe
either, but it scares me a lot less.

The reaction given should affect tertiary amines MUCH slower than primary 
amines (but not leave them totally untouched).

                                         Steve
Newsgroups: sci.chem
From: cfthb@ux1.cts.eiu.edu (Howard Black)
Subject: Re: Structure of nonoxynol-9 wanted
Date: Fri, 28 Aug 1992 14:51:23 GMT
Organization: Eastern Illinois University
Keywords: nonoxynol-9, structure, search, database

In article <1992Aug28.013052.114803@zeus.calpoly.edu> dfield@zeus.calpoly.edu (Daniel R. Field) writes:
>
>     At the ACS national meeting in San Francisco, several representatives
>from the chemical databases (STN, Dialog...) attempted to help me find
>the structure of nonoxynol-9, the common over-the-counter spermicide, but
>to no avail.  
>     If anyone could direct me to the appropriate resource to find this
>structure, I would appreciate it.  If you could e-mail me the diagram,
>I would be very happy.  A mailed photocopy of the diagram would be
>cherished! :)    That could go to: Dan Field, P.O. Box 13932, 
>San Luis Obispo, CA 93406-3932

    Nonoxynols are a series of polyethers with the general structure:


       C9H19-C6H4-(OCH2CH2)n-OH  (C6H4 is a para-disubst. benzene ring)

		when n=9, it's nonoxynol 9.

-- 
   ******************************************************************
     Howard Black                             cfthb@ux1.cts.eiu.edu
     Department of Chemistry                  Eastern Illinois Univ. 
Newsgroups: sci.chem
From: cfthb@ux1.cts.eiu.edu (Howard Black)
Subject: Re: arcane rearrangement
Date: Thu, 27 Aug 1992 19:59:14 GMT
Organization: Eastern Illinois University

In article <1992Aug25.174207.20706@mnemosyne.cs.du.edu> aankrom@nyx.cs.du.edu (Anthony Ankrom) writes:
> A well-known chemist has suggested that the following rearrangement is
>possible, but he failed to elaborate. (He mentioned it in passing.) I'm
>curious as to how the reaction proceeds and wondered anyone out in Netland
>had any idea...
>
>   Ar-CH=CH-C-NRR'         (?)              Ar-CH2-CH-CH3
>            "         --------------->             |
>            O          X # steps (?)               NRR'
>
> In case my ascii structures are unclear, the starting product is an Aryl
>substituted acrylic acid amide, the final product is an 1-Aryl-2-amino
>propane. (R, R' = H)

    Your ascii structures are very clear....the structure of amphetamine is
hard to miss.  Perhaps the DEA can help you.

-- 
   ******************************************************************
     Howard Black                             cfthb@ux1.cts.eiu.edu
     Department of Chemistry                  Eastern Illinois Univ.
From: RS0VRD@rohvm1.rohmhaas.com (Ross Druker)
Newsgroups: sci.chem
Subject: chemistry ftp sites
Date: 31 Aug 92 17:20:00 GMT
Organization: Rohm and Haas Company

Hi,
Can you tell me if there are ftp sites that specialize in chemistry or
chem eng. software or information?

Ross Druker
Rohm and Haas Co.
rs0vrd@rohmhaas.com
From: bjgaed@bb1t.monsanto.com
Newsgroups: sci.chem
Subject: Re: the TRUTH about Methylene Chloride
Date: 28 Aug 92 07:25:57 CST
Organization: Monsanto Company, St. Louis, MO

In article <BtnKoI.4I0@news.cso.uiuc.edu>, nash@aries.scs.uiuc.edu (David Nash) writes:
> 
> Frankly, requiring showering after so much as using a
> bottle of methylene chloride seems a bit extreme, but I still wouldn't want to 
> get the stuff all over my hands.  (I've done it once already and don't 
> particularly want to repeat the experience.)
> 

You think *that's* bad.  In grad school, many years ago, I set a 1 
liter bottle of methylene chloride down on the bench and had the 
bottom break out, dumping the whole bottle down the front of my pants. 
Rather than shock the very nice lady postdoc who was in the lab at the 
time, I dashed for the men's room and got my clothes off *fast*.  I 
was standing there, naked from the waist down, waving my undershorts 
in the air amid a cloud of fumes when a very distinguished full 
professor of organic chemistry walked in, looked at me, and just 
turned around and walked out.  My only thought at the time was:

"I just *know* Professor Y. is going to be on my thesis committee."

(He wasn't)  8{)


-- 
--Electric Monk            (Bruce Gaede); 
                            e-mail: bjgaed@ccmail.monsanto.com

"...and then time started seriously to pass."
--Douglas Adams, _Dirk Gently's Holistic Detective Agency_
Newsgroups: sci.chem
From: mort@quads.uchicago.edu (Dave Mortman)
Subject: Re: chemistry ftp sites
Reply-To: mort@midway.uchicago.edu
Organization: Quantum Chemicals; University of Chicago Dept of Chemistry
Date: Tue, 1 Sep 1992 14:35:46 GMT

I too would be interested in the afformentioned information

Dave Mortman
Room 810B
1005 East 60th Street
Chicago, IL 60637
(312) 702-6367 (after Sept 25)
(513) 891-7359
mort@midway.uchicago.edu


							Thanks
							-Dave

Newsgroups: sci.chem
From: knapp@spot.Colorado.EDU (David Knapp)
Subject: Re: Sparking grapes
Organization: University of Colorado, Boulder
Date: Tue, 25 Aug 1992 18:35:59 GMT

In article <Bt70w9.6uA@news.cso.uiuc.edu> berger@atropa (Mike Berger) writes:
>
>Most grapes are not electromagnetic in nature.


Was this arrived at emprically?  ;-)


-- 
David Knapp                                      University of Colorado, Boulder
Highly Opinionated, Aging  and                      knapp@spot.colorado.edu
Perpetual Student of Chemistry and Physics.
            Write me for an argument on your favorite subject.
From: Jochen_Lichtenthaeler@lu.maus.de (Jochen Lichtenthaeler)
Newsgroups: sci.chem
Subject: was ist das ?
Date: 29 Aug 92 17:28:00 GMT
Organization: MausNet
X-Gateway: MausGate/News 1.11

Was tut sich in dieser Gruppe, bzw. was soll sich dort tun ?
Ich bin Dipl.-Chem. und interessiert an EDV in der Chemie sowie
TeX als "Textverarbeitung".

Gruss Jochen
Newsgroups: sci.chem
From: windsong@nevada.edu (Anne Racel)
Subject: temporary Analytical Chemist position
Organization: University of Nevada, Las Vegas
Date: Fri, 4 Sep 1992 19:22:44 GMT

    Posted for:
 "Nancy E. Carpenter" <carpenne@cda.mrs.umn.edu>

Due to a recent and unexpected retirement, the following position in
chemistry is now open:
ANALYTICAL CHEMIST. Temporary position beginning January 1993 at the
University of Minnesota, Morris.  Duties: teach Instrumental Analysis
in winter and Analytical Chemistry in spring.  Scholarly research
and some service responsibilities are expected.  Appointment at
Assistant Professor level for Ph.D., Instructor for others. Salary
negotiable.  Tenure-track search expected later.  Minimum qualifications:
M.S. or M.A. in chemistry with analytical background and one year
teaching experience (graduate TA experience acceptable). Ph.D. in
analytical and excellence in teaching preferred.  Send application,
resume, transcripts and three reference letters via U.S. mail to:
Dr. Michael Korth, Chair, Division of Science and Mathematics,
University of Minnesota, Morris; Morris, MN 56267-2128 to arrive
by October 23, 1992.  The University of Minnesota is an equal
opportunity educator and employer.
-- 
    Anne Racel                Internet:  windsong@nevada.edu
    University of Nevada,   Compuserve:  72105,1105
    Las Vegas                   Bitnet:  windsong@nevada3
    "experience teaches that silence terrifies people the most"
Newsgroups: sci.chem
From: s9874194@phobos.ucc.umass.edu (s9874194)
Subject: Re: whiskey bottle
News-Software: VAX/VMS VNEWS 1.41    
Organization: University of Massachusetts, Amherst
Date: Mon, 31 Aug 1992 13:45:00 GMT

In article <1992Aug31.120649.24027@alf.uib.no>, ttt@cmr.no (Tore Tjomsland) writes...
>Yesterday I was cleaning up the lab. I found a 
>beautiful bottle. It contained a liquid, and was
>marked: "platinum chloride".
> 
>As noted above, the bottle is beautiful, and I
>want to use it in my private bar.
> 
>I therefore wonder if anyone has got health
>data (oral) for the platinum chloride. Will it
>be safe to drink from the bottle after a simple
>wash? And have you got any good suggestions on 
>how I should get rid of the platinum cloride? 
> 
>Thanks in advance!
> 
>Regards,
> 
>Tore Tjomsland
>e-mail:	ttt@cmr.no
Wash that with some nitric acid and plenty of water will be safe enough
Newsgroups: sci.chem
From: knapp@spot.Colorado.EDU (David Knapp)
Subject: Re: airbags how do they work? Chemistry??
Organization: University of Colorado, Boulder
Date: Tue, 25 Aug 1992 17:04:15 GMT

In article <15AUG199212012653@juliet.caltech.edu> natefrei@juliet.caltech.edu (Frei, Nathan A.) writes:
>In article <1992Aug14.201208.14279@engage.pko.dec.com>, moroney@ramblr.enet.dec.com writes...
>>In article <cs_jh.555@cox.nsac.ns.ca>, cs_jh@cox.nsac.ns.ca (JEFF HOYLE) writes...
>>>Some time ago I posted a request for info concerning the chemistry involved 
>>>in air bag inflation.  I did not get any useful responses.  Is there any one 
>>>out there who either knows and can explain the process or who has a leading 
>>>reference to this subject.
>> 
>>I believe they use sodium azide, which explodes producing a sudden large
>>volume of nitrogen gas.
>> 
>>Sodium Azide is NaN .
>>                   3
>>-Mike
>
>That sounds right.  Incidentally, the rxn is highly exothermic (only logical,
>considering that it produces tens of liters of gas in milliseconds), meaning
>that a people suffer second or third degree burns from airbags.  Auto
>manufacturers (and most folks tend to agree) that this is a reasonable
>price for an increased survival rate.

Is the thermal mass (specific heat) of gaseous nitrogen so high that it can 
heat water (skin) to any significant degree during a second or two contact?
I find it hard to believe this and also find it hard to believe that the 
adiabatic expansion of the gas doesn't help cool the exothermicity of that
reaction immensely. Do you have references for these people with burns?

-- 
David Knapp                                      University of Colorado, Boulder
Highly Opinionated, Aging  and                      knapp@spot.colorado.edu
Perpetual Student of Chemistry and Physics.
            Write me for an argument on your favorite subject.
Newsgroups: sci.chem
From: knapp@spot.Colorado.EDU (David Knapp)
Subject: He who laughs last... was Re: Let's have a laugh
Organization: University of Colorado, Boulder
Date: Tue, 25 Aug 1992 16:58:16 GMT

In article <1992Aug15.035241.2924@news.Hawaii.Edu> belli@uhunix.uhcc.Hawaii.Edu (Jack Belli) writes:
>  Are we forgetting one of the first things one learns as a synthetic chemist?
>Namely,if you can buy something at a reasonable price and in the required
>purity then don't bother making it.I would suggest a visit to the nearest lab
>with an AA and filling your balloons,garbage bag or whatever with reagent
>grade 
>N2O  then have a gas..........................


I would like to just add that this is a great way to have your *last* laugh.
Many people die each year from suffocation resulting from using this bag
technique.  Some die because they pass out from the nitrous oxide, then
have their face buried in the bag.  Two hospital janitors from my home
state died *at the same time* because they had both inhaled the latex
gloves they were taking tokes out of.

Perhaps you could use a rigid container; nitrous under glass?  In any case,
think before you do that kind of stuff.


-- 
David Knapp                                      University of Colorado, Boulder
Highly Opinionated, Aging  and                      knapp@spot.colorado.edu
Perpetual Student of Chemistry and Physics.
            Write me for an argument on your favorite subject.
Newsgroups: sci.chem
From: singley@helix.nih.gov (Erick D. Singley)
Subject: Re: Chemical Safety
Organization: (National Institutes of Health, Bethesda, MD)
Distribution: sci.chem
Date: Fri, 28 Aug 1992 19:39:04 GMT

If you have information concerning safety practices that your 
supervisors tell you to disregard (or if you know better than they and don't
correct it) AND DO IT ANYWAY then you can be held personally liable.
For instance: Aberdeen Testing Facil (near Jessup) people with such safety 
knowledge were told by supervisors to dump chemicals illegially on site.
They did so, and were reciently convicted of environmental damage laws.
EVEN THOUGH their Supervisors told them so (and were gov. employees)

So, yes, you are personally responsible for your actions, but should only
be resposible for the actions of company and employees if you are in that
chain of command (ie Safety officer)
From: css1rs@gondor.mcs.surrey.ac.uk (Russell Smithers)
Newsgroups: sci.chem
Subject: Freon (effects)
Date: 4 Sep 92 09:27:15 GMT
Organization: University of Surrey, Guildford, England
X-Newsreader: Tin 1.1 PL4

What effect would a small quantity of freon have on someone if
inhaled?

Thanks.
Reply's via e-mail please.
Newsgroups: sci.chem
From: knapp@spot.Colorado.EDU (David Knapp)
Subject: Re: the TRUTH about Methylene Chloride
Organization: University of Colorado, Boulder
Date: Tue, 25 Aug 1992 17:14:43 GMT

In article <1992Aug17.200337.9530@uoft02.utoledo.edu> dsmith@uoft02.utoledo.edu writes:
>If they will forgive me, the following is taken from the Merck Index, 10th
>Edition, page 869, item 5936, Methylene Chloride:
>
>	Human Toxicity:  Narcotic in high concns.
>	Use:  Solvent for cellulose acetate; degreasing and cleaning fluids,
>	      as solvent in food processing.
>	Therap Cat:  Pharmaceutical aid (solvent)

But this doesn't support an assertion that it is harmless.  Tri-chlor has
been used to decaffeinate coffee and you wouldn't go drinking tri-chlor, right?
Tri-chlor is nasty stuff but we don't mind rinsing it through our coffee
because we can make sure there is no significant residue.

I don't have references handy to make any assertion about methylene chloride's
toxicity but I wouldn't take this blurb from Merck as support for anything.

>
>So, if all of you chemophobes and rumormongers don't mind - DON'T GO TALKING
>ABOUT SOMETHING UNTIL YOU CHECK YOUR FACTS.

We are *all* guilty of this though, aren't we?

>Obviously, as with any chemical
>(which means any matter in the universe) too much is bad for you.  (Even
>too much oxygen can hurt or kill you in the right circumstances.  Just ask
>a scuba diver.)

I'll vouch for that. Except it isn't quantity that is bad, it's the biological
reactivity under pressure (what I was taught in my three certifications, no
references handy.)  Beyond 1 atmosphere, oxygen can be toxic.

>I don't mind concern by uninformed or lay persons, or even those who think
>they might know but aren't sure.  The worst enemy we have is ignorance.
>But when chemists start passing bad information, that hurts everyone.  I
>don't pretend to know everything, and I would not have put my two cents in,
>but this subject was starting to get out of hand.  As a chemist and teacher,
>I feel that the only way people and society will advance will be to take the
>mystery out of (IMHO) simple sciences such as chemistry, since everything
>is chemistry.
>
>Doug Smith, Ph.D.
>Assistant Professor of Chemistry
>The University of Toledo
>
>"The technology of a sufficiently advanced civilization is indistinguishable
>from magic."


-- 
David Knapp                                      University of Colorado, Boulder
Highly Opinionated, Aging  and                      knapp@spot.colorado.edu
Perpetual Student of Chemistry and Physics.
            Write me for an argument on your favorite subject.
Organization: Arizona State University
Date: Wednesday, 26 Aug 1992 22:20:36 MST
From: Shooting Club at ASU <GUNDEVIL@ASUACAD.BITNET>
Newsgroups: sci.chem
Subject:    Heaviest Element


    Heaviest Element Discovered                            Ver25Aug92

        The heaviest element known to science was recently discovered
    by scientists at Arizona State University.  The element, tentatively
    named 'Administratium' (Ad), has no protons or electrons, thus it
    has atomic number 0.

        Ad does, however, have a neutron, 75 associat-neutrons, 125
    deputy-neutrons and 111 assistant-deputy-neutrons.  This yields an
    atomic mass of 312.

        These 312 particles are held together in the nucleus by a force
    that involves the continuous exchange of meson-like particles called
    memos.

        Because it has no electrons, 'Administratium' is inert.  Never-
    theless, it can be detected chemically, because it seems to impede
    every reaction in which it takes part.

        According to Dr. M. Languor, one of the discoveries of the
    discoverers of the element, is that a very small amount of 'Administrat-
    ium' can make one reaction, that normally takes less than a second,
    require more than four days for completion.

        In addition, the molecule has an affinity for others with the
    weakest constitution, and will gravitate towards the most liberal
    compositions but, "One can never be sure what's going to happen when
    Ad reacts with other molecules."

        'Administratium' has a half-life of approximately three years.
    At the end of this time it does not actually decay.  Instead, it
    undergoes an internal reorganization in which the associates to the
    neutron, deputy-associates to the neutron, and assistant-deputy-
    neutrons, all exchange places.

        Some studies indicates that the atomic mass actually increases
    after each reorganization.

    Anon.
From: kkniaz@eniac.seas.upenn.edu (Krzysztof W. Kniaz)
Newsgroups: sci.chem
Subject: good organic donor...
Keywords: buckyballs, intercalation, organic donor
Date: 25 Aug 92 23:02:02 GMT
Organization: University of Pennsylvania

As some of you may know Fred Wudl at the Univ. of Calif in Santa Barbara
succeeded in dopind C60 with TDAE (tetrakisdimethylpaminoethylene), obtaining
a new intercalation compound, which is ferromagnetic below 16K. Although
many question his magnetism data, he firmly supports his finding.

Question does anyone know about particularly good organic donor (at least
as good as TDAE)? Resistance to elevated temperatures (say 300C) would be
a plus. 

Thanks.
Chris



--

Krzysztof Kniaz, University of Pennsylvania | If you can't learn  
Lab for Research on the Structure of Matter | to do it well,
Philadelphia, PA, 19104, USA                | learn to enjoy doing it badly.
Newsgroups: sci.chem,rec.autos,rec.autos.tech,misc.consumers,sci.environment,talk.environment
From: knapp@spot.Colorado.EDU (David Knapp)
Subject: Re: Carburetors, gasoline, and why I don't recycle
Organization: University of Colorado, Boulder
Distribution: na
Date: Thu, 3 Sep 1992 14:51:44 GMT

In article <Btz7xq.H47@news.cso.uiuc.edu> cec35848@uxa.cso.uiuc.edu (Chuck Carroll) writes:
>1)  You'll need a pretty good estimate of friction, since without it
>it would take no energy to move a car over level ground. 


What about W=F*d?  Ek=1/2m*(dV)^2?  P=m(dV)?



-- 
David Knapp                                      University of Colorado, Boulder
Perpetual Student                                   knapp@spot.colorado.edu
Newsgroups: sci.chem
From: pbays@bach.helios.nd.edu (phil bays)
Subject: Sparkles in the Air 
Way: when the hot concentrated methanol solution of 
Organization: Saint Mary's College , Notre Dame
Distribution: sci.chem
Date: Thu, 3 Sep 1992 16:54:38 GMT


Newsgroups: sci.chem,rec.autos,rec.autos.tech,misc.consumers,sci.environment,talk.environment
From: joec@fid.morgan.com (Joe Collins)
Subject: Re: Carburetors, gasoline, and why I don't recycle
Organization: None
Distribution: na
Date: Wed, 2 Sep 1992 20:55:00 GMT

>In article <1992Sep02.010828.24870@rs6000.cmp.ilstu.edu> ejhupper@rs6000.cmp.ilstu.edu (Eric Huppertz) writes:

Eric writes a long article about how the oil companies et al have 
discovered a way to get excellent miles per gallon but won't release
it for sale since the price of oil/gasoline would plummet. Thus, they
keep the technique locked up in a vault and thus have been screwing
the customer all these years.

It should be fairly to prove/disprove this, emperically.

Simply put, look up the potential energy in a gallon of automotive
gasoline. Factor in inefficiencies due to friction, heat loss and so forth.
The resultant energy is available to move a vehicle a distance of X miles.
BTW- I would guess a car is less than 20% efficient. Even electrical
companies are only 40-50% efficient, with the rest lost to friction (motor
bearings, fluid flow), heat loss (steam, etc), electrical resistance 
in the transmission lines.

I don't have the numbers nor have a handle on the energy of gasoline but
any good chemist/physicist should be able to run the numbers and prove
or disprove Eric's point. 

Personally, I'll bet the numbers disprove Eric's point.

Joe
joec@morgan.com
From: kkniaz@eniac.seas.upenn.edu (Krzysztof W. Kniaz)
Newsgroups: sci.chem
Subject: Re: Chemie-Programme in @ RS
Date: 25 Aug 92 18:40:42 GMT
Organization: University of Pennsylvania

In article <2a8a995fwnr070@ark.abg.sub.org> ralf@ark.abg.sub.org (Ralf Stephan) writes:
>Thorsten_Floeck@rs.maus.de (Thorsten Floeck) writes:
>> Hallo Chemiker,
>>...
>
>If you want us to read your infos, please write English.
>
>--ralf
>-- Telepathy is just a trick:  once you know how to do it, it's easy. (nh)

In contrary, some of us understand and appreciate entries in German.

--

Krzysztof Kniaz, University of Pennsylvania | If you can't learn  
Lab for Research on the Structure of Matter | to do it well,
Philadelphia, PA, 19104, USA                | learn to enjoy doing it badly.
Newsgroups: sci.chem,sci.physics