From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus rearranged T-cell receptor alpha chain (V-J-C)
Date: 15 Aug 92 10:02:41 GMT
Distribution: bionet
Checksum: 03927     4

LOCUS       MUSTCRAVJC   1349 bp ss-RNA             ROD       15-AUG-1992
DEFINITION  M.musculus rearranged T-cell receptor alpha chain (V-J-C)
ACCESSION   X67127
KEYWORDS    T-cell receptor; T-cell receptor alpha; constant region;
            joining region; variable region.
SOURCE      Mus musculus RNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Austrup,F., Kodelja,V., Kucharzik,T. and Klsch,E.
  TITLE     Characterization of idiotype-specific I-Ed-restricted T suppressor
            lymphocytes which confine immunoglobulin class expression to IgM in
            the anti-a(1-3) dextran B 1355 S response of BALB/c mice
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1349)
  AUTHORS   Kodelja,V.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: strain=BALB/c; *source: stage=adult; *source: tissue=
            spleen; *source: cell_type=T-cells; *source: clone_library=lambda
            ZAP; *source: clone=CD3+, 4+, 5+, 8-; *source: chromosome=14;
            *source: is_germline=N;
            From EMBL    entry MMTCRAVJC;  dated 03-AUG-1992.
FEATURES             Location/Qualifiers
     CDS             53..856
                     /product="T-cell receptor alpha chain (VJC)"
                     /codon_start=1
                     /translation="MQRNLVAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCN
                     FSIAATTVQWFLQNPRGSLINLFYLVPGTKENGRLKSTFNSKESYSTLHIRDAQLEDS
                     GTYFCAAEANSGYNKLTFGKGRVLLVSPDIQNPEPAVYQLKDPRSQDSTLCLFTDFDS
                     QINVPKTMESGTFITDKTVLDMKAMDSKSNGAIAWSNQTSFTCQDIFKETNATYPSSD
                     VPCDATLTEKSFETDMNLNFQNLSVMGLRILLLKVAGFNLLMTLRLWSS"
     misc_feature    53..112
                     /note="leader"
     misc_feature    113..383
                     /note="variable region (V alpha 11.3)"
     misc_feature    384..442
                     /note="joining region (J alpha new 11)"
     misc_feature    443..1349
                     /note="constant region (C alpha)"
BASE COUNT      357 a    351 c    315 g    326 t
ORIGIN
        1 caagacaccc ttcagggctg gagagaagac aactagcgat tggacagggg ccatgcagag
       61 gaacctggtt gctgtgctgg ggattctgtg ggtgcagatt tgctgggtga gcggagataa
      121 ggtgaagcaa agtccctcag cgctgagtct ccaagaggga accaattctg ctctgagatg
      181 caatttttct atcgccgcga caactgtgca gtggttccta cagaatccca ggggcagcct
      241 catcaatctt ttttacctgg ttccaggaac aaaggagaat gggaggttaa agtcaacatt
      301 caattctaag gagagctaca gcaccctgca catcagggat gcccagctgg aggactcagg
      361 cacttacttc tgtgctgctg aggccaactc gggatacaac aaactcactt ttggaaaggg
      421 cagggtactt ctagtctctc cagacatcca gaacccagaa cctgctgtgt accagttaaa
      481 agatcctcgg tctcaggaca gcaccctctg cctgttcacc gactttgact cccaaatcaa
      541 tgtgccgaaa accatggaat ctggaacgtt catcactgac aaaactgtgc tggacatgaa
      601 agctatggat tccaagagca atggggccat tgcctggagc aaccagacaa gcttcacctg
      661 ccaagatatc ttcaaagaga ccaacgccac ctaccccagt tcagacgttc cctgtgatgc
      721 cacgttgacc gagaaaagct ttgaaacaga tatgaaccta aactttcaaa acctgtcagt
      781 tatgggactc cgaatcctcc tgctgaaagt agcgggattt aacctgctca tgacgctgag
      841 gctgtggtcc agttgaggtc tgcaagactg acagagcctg actcccaagt tccgtcctcc
      901 tcacccctcc gctccctctt caagccaaaa ggagccggct gtctggggtc tggttggccc
      961 tgattcacaa tcccacctgg atctcccaga tttgtgagga aggttgctag agagctaagc
     1021 gctgctgccg cacccactca gctccctcac tgctgctgac cattcacaaa aaaaaaaaac
     1081 ggcaggggcg gggcttctcc tggatctgaa gacccctccc ccatggcaga ctcccctata
     1141 aaatctcttg gagaatgttg taaaaaatat gggttttttt tttttggcgg gtttactttt
     1201 ttaagcatcc ataaagaaat gcatattact ctttcatcaa ggtgtagaaa ttatctcatt
     1261 gtctagaccc tcctgctact gtgtgtattg agccacattg tatattattc tgctgcccat
     1321 gacatcatta aaggtgattc agaaaaacc
//