From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Ginglymostoma cirratum MHC class II protein mRNA.
Date: 7 Jan 93 05:46:29 GMT
Distribution: bionet
Checksum: 19332 4

LOCUS       GINMHAA      1206 bp ss-mRNA            VRT       06-JAN-1993
DEFINITION  Ginglymostoma cirratum MHC class II protein mRNA.
ACCESSION   M89950
KEYWORDS    alpha chain; cell surface glycoprotein; class II gene;
            integral membrane protein; major histocompatibility complex.
SOURCE      Ginglymostoma cirratum spleen cDNA to mRNA.
  ORGANISM  Ginglymostoma cirratum
            Eukaryota; Animalia; Chordata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Euselachii; Neoselachii; Batoidea;
            Orectolobiformes; Ginglymostomatidae.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Flajnik,M.F., McKinney,E.C., Sato,K., Vazquez,M. and Kasahara,M.
  TITLE     Evolution of the major histocompatibility complex: Isolation of
            class II A cDNA clones from the cartilaginous fish
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89, 6688-6692 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     88..147
                     /codon_start=1
     mat_peptide     148..828
                     /product="MHC class II protein"
                     /codon_start=1
     polyA_signal    1190..1195
     CDS             88..831
                     /product="MHC class II protein"
                     /codon_start=1
                     /translation="MEARNYFSVLVLVLIQGGWAGKYLYDFTQVYFVQQRSPEKHFDV
                     MEDGDEIFYMDFNLKKEVARIPEFAHLYMQGGEAGISANIAIVKNNLKVVMNLSGGTP
                     EPKVPPEVSVYSEDLVEWGQLNTLICFADGFYPPHITMKWRRNNEPMTDGDNITEFYI
                     KDDFTYRRFSYLSIVPSPGDMYSCHVEHSSLQDPVTVFWDQGVPEEKSGPGTIICALG
                     LTLGIISAVVGIILLIKERQRLQAQQHGI"
BASE COUNT      336 a    237 c    281 g    352 t
ORIGIN      
        1 ctaacgtgtg ggagagaaac acagcaatcc aagaggagct ggcactgggt gaagactgtc
       61 gcatctcaga gaatcgagaa gctcagaatg gaagcgagga attacttttc cgtgttggtg
      121 ctggttttaa ttcaaggagg ctgggctgga aaatatctgt acgatttcac ccaggtgtat
      181 tttgtgcagc agcgcagtcc cgagaaacac tttgatgtga tggaggacgg agatgagatt
      241 ttctacatgg acttcaacct gaagaaggag gtggcccgga tccccgagtt tgcccatctt
      301 tacatgcagg gaggagaggc gggaatctca gccaatatcg ccatcgtcaa aaacaatttg
      361 aaagttgtta tgaacctgtc cggcgggacc ccggaaccga aagttccccc tgaagtctct
      421 gtgtattctg aagaccttgt agaatggggg cagctgaaca cattgatctg ttttgctgat
      481 ggattctacc ctccacacat caccatgaag tggagaagaa acaatgagcc catgactgat
      541 ggcgataaca tcactgagtt ctatattaaa gacgatttta catatcgtag attttcatac
      601 ctgagcattg tcccgagtcc tggagacatg tactcctgtc atgtggaaca ttcgagccta
      661 caggatccag taactgtatt ctgggatcag ggagtacctg aggaaaagtc tggtcctggg
      721 acaataatct gtgctctggg actcaccctg ggaattatca gtgctgttgt aggaatcatt
      781 ttactgatta aagagagaca gcggttgcaa gctcagcagc atggcatcta ggggtaccct
      841 cattgtgatg cagaaattca atactgaagg ttctacgatg aaaatgcgtc aagtttgaaa
      901 ttatgtcttt attgggttaa aactacctta cgatattgtc tgatctaaat tatctgccaa
      961 caatggaaat ctactcatac tttcagattt gtaacagata ttattgtcat aagtacaatg
     1021 tctcctgttt cctaaacgtt actattcaag gcatgtctta taacaaggcc actttgttaa
     1081 tttggttgtg gaatcctgat tgatttaaac ataatcaggg tctgcatttt gttcactttc
     1141 tagtttgatt ttcagtgttc tgtaaatccc tgttctacat tctatttgca ataaatactg
     1201 ttaatt
//