From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Pneumocystis carinii beta-tubulin gene, complete cds.
Date: 3 Jan 93 22:08:05 GMT
Distribution: bionet
Checksum: 17330 7

LOCUS       PMCBT        2876 bp ds-DNA             INV       21-DEC-1992
DEFINITION  Pneumocystis carinii beta-tubulin gene, complete cds.
ACCESSION   L05466
KEYWORDS    beta-tubulin; tubulin.
SOURCE      Pneumocystis carinii (library: lambda EMBL3) DNA.
  ORGANISM  Pneumocystis carinii
            Eukaryota; Animalia; Protozoa; Sarcomastigophora; Sarcodina.
REFERENCE   1  (bases 1 to 2876)
  AUTHORS   Edlind,T.D., Bartlett,M.S., Weinberg,G.A., Prah,G.N. and Smith,J.W.
  TITLE     The beta-tubulin gene from rat and human isolates of Pneumocystis
            carinii
  JOURNAL   Mol. Microbiol. 6, 3365-3373 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            <745..756
                     /number=1
     intron          757..818
                     /number=1
                     /note="putative"
     exon            819..834
                     /number=2
     intron          835..892
                     /number=2
                     /note="putative"
     exon            893..912
                     /number=3
     intron          913..1012
                     /number=3
                     /note="putative"
     exon            1013..1068
                     /number=4
     intron          1069..1142
                     /number=4
                     /note="putative"
     exon            1143..1197
                     /number=5
     intron          1198..1238
                     /number=5
                     /note="putative"
     exon            1239..1649
                     /number=6
     intron          1650..1714
                     /number=6
                     /note="putative"
     exon            1715..1970
                     /number=7
     intron          1971..2028
                     /number=7
                     /note="putative"
     exon            2029..2456
                     /number=8
     intron          2457..2523
                     /number=8
                     /note="putative"
     exon            2524..>2598
                     /number=9
     CDS             join(745..756,819..834,893..912,1013..1068,1143..1197,
                     1239..1649,1715..1970,2029..2456,2524..2598)
                     /citation=[1]
                     /note="putative"
                     /product="beta tubulin"
                     /codon_start=1
                     /translation="MREIVHLQTGQCGNQIGASFWSTISGEHGLDSTGVYQGTSDLQL
                     ERMNVYFNEASGGKYVPRSILIDLEPGTMDAVRSGPFGNLFRPDNFVFGQSGAGNNWA
                     KGHYTEGAELVDSVLDVVRREAEACDCLQGFQITHSLGGGTGAGMGTLLISKIREEYP
                     DRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLP
                     DPGYGDLNHLVSAVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFIVGFAPLTSK
                     GSHSFRSLTVPELTQQMFDAKNMMAASDPRHGRYLTVAAIFRGRVSMKEVEDQMHSVQ
                     QKNSSYFVEWIPNNVQTALCSIPPRGLKMSSTFIGNSTSIQELFKRVGDQFSAMFRRK
                     AFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYEIAGVDEEVELDDEIET"
BASE COUNT      891 a    443 c    464 g   1078 t
ORIGIN      
        1 aagcttctaa aagagaatca taataaatat tataaaataa tttttatttt actggacttt
       61 tatttcactg atttcaatat tatctatcta tatatcttta ttggttagac gaaatattta
      121 aaataattgc ataatatttt tattcttata aaaatgatct caataatata tccatcaatc
      181 aagaaataat attttaataa actaatatct tgattttagt atttaatcat attattttaa
      241 aggttttaat aatctatttt tgtttatata attgcattaa ttataattga tataatattt
      301 ataatcttta tatactaatc atatatattt ttagttatct ctattatata tgaattaata
      361 agtattcgat atctcttcta ttctaatagt aagatgttat ttatattata tataattcta
      421 cataatataa ttctacataa tataatctat atatacctta tacattattc atttcaaatt
      481 tataaccttt ttattgattc aactaagcat tctttataaa ctcatcccaa ccctaacccc
      541 gtagttccaa ccctaaccgt agttccaacc ctaacccaac ccatcaccta actctccact
      601 tcaccctaac ctgcataccc taaccctact cataccctac cctgatgtac aacaaatcac
      661 gtgattcgct gaaaaagcta gacgtgtcaa caattcgaat cattcaagac aaactttttt
      721 caaaatatac gttttgtcta aaatatgaga gaaattgtat gttttacccc caatttttta
      781 gttttaagca atttctaacc tctttttctt ttaaataggt ccatcttcaa acaggtgcgt
      841 ttttttcccg tcttttttag acctattttc atcatttttt tatttcttac aggacaatgt
      901 ggaaaccaga ttgtaagtta ttttacatga ttatttagga tatatatgcg cgcattgatc
      961 gacgtatata ttctttttta ttgaaaatta ttcctttatt catgagtttc agggcgcgtc
     1021 tttttggtct acaattagcg gagaacatgg tttagatagc acaggagtgt aagtttctat
     1081 acgcggatga tatatttcat cgcgttttcc gagtatattt tttctaagat ttttgagtta
     1141 agttatcagg gtacatctga cctacaactt gaacgtatga atgtctattt taatgaggta
     1201 acgatatata tacggattat atatcttatg agaaataggc atctggcgga aaatatgttc
     1261 ctcgatcgat attaattgat cttgaaccgg gtactatgga tgcggtaaga tcgggaccat
     1321 ttggcaatct ttttcggcca gataattttg tttttggtca atctggagca gggaataatt
     1381 gggcaaaagg gcattataca gaaggagcgg aattggtaga ttccgtatta gatgtagttc
     1441 gtcgagaagc agaagcttgt gattgtttac aagggtttca aattacgcat tctcttggtg
     1501 gtggaacggg tgcgggtatg gggacattat taatttcaaa aattcgagaa gaatatccgg
     1561 atcgaatgat ggcaacgttt tcggtagttc catcgccaaa agtttcggat acagtggtag
     1621 aaccatacaa tgcgacgctt tctgtacacg tatgttttta tttttgtttt ttttttttgg
     1681 ggggcataaa gacaagggta ttgatgttaa atagcaatta gtggaaaatt cggatgaaac
     1741 gttttgtatt gataatgaag ctttatatga tatttgtatg cgaacgttaa aactcccgga
     1801 tccaggatat ggtgatttaa atcatttggt atcagcagta atgagtggta ttacgacatg
     1861 tcttcgattt cccggacagc ttaattcaga tttacgtaaa ttggctgtaa acatggtacc
     1921 atttcctcga ttgcactttt tcattgttgg atttgcgcca ttaacaagca gtatgttttg
     1981 ttttgttttg tttattttaa caattgttaa tataaatgtg taataaagag gggtcacatt
     2041 ctttccgctc tttaacagtt ccggaattaa cacagcaaat gtttgatgca aaaaatatga
     2101 tggctgcttc agatccaagg catggacgat atttaacggt tgcagcaatt ttccgtggtc
     2161 gagtatcgat gaaagaagtg gaagatcaaa tgcatagtgt tcaacaaaag aattcctcat
     2221 attttgtcga atggattccc aataatgtgc aaactgcatt gtgttcaatt ccaccaaggg
     2281 gacttaaaat gtcatctact tttattggta attctacatc gattcaggag ctcttcaaac
     2341 gagtgggcga tcaattttca gcaatgtttc gacgtaaagc atttttgcat tggtatacgg
     2401 gcgaaggaat ggatgaaatg gaattcacag aagctgaatc aaacatgaat gatctggtac
     2461 gtcttttaaa atattttatt attcattttg tttggttttc taattttttt tttaaaaata
     2521 taggttagtg aatatcaaca atacgaaata gctggcgtcg atgaagaagt agaacttgat
     2581 gatgagattg aaacataaat ggtcatttat taataaatat tgctgatcat tcttgatctt
     2641 cgattattat tagctcatct cgctatttta tctccttcgt atatttattt tttgaccgtt
     2701 tatatataaa tatgtaatgt gtatgaactt gcgttaaaca tgcttgcttt attttttcta
     2761 taatcttaag acctttaccc aagcatcctt atatcctttt tttcttaaat cctatccttt
     2821 ctataccata aaataataag ttaggatctt aaaagaagtc ctattgtatc agatct
//