From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: R.rattus mRNA for guanine nucleotide releasing factor for RAS P21
Date: 15 Aug 92 10:03:06 GMT
Distribution: bionet
Checksum: 00422     8

LOCUS       RATRASGRF    3804 bp ss-RNA             ROD       15-AUG-1992
DEFINITION  R.rattus mRNA for guanine nucleotide releasing factor for RAS P21
ACCESSION   X67241
KEYWORDS    guanine nucleotide releasing factor; releasing factor.
SOURCE      Rattus rattus RNA.
  ORGANISM  Rattus rattus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 3804)
  AUTHORS   Shou,C., Farusworth,C.L., Neel,B.G. and Feig,L.A.
  TITLE     Molecular cloning of cDNA encoding a guanine nucleotide releasing
            factor for ras P21
  JOURNAL   Nature 358, 351-354 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=adult; *source: tissue=brain; *source:
            clone_library=lambda gt10;
            From EMBL    entry RRRASGRF;  dated 03-AUG-1992.
FEATURES             Location/Qualifiers
     CDS             70..3804
                     /product="P140 RAS-GRF"
                     /codon_start=1
                     /translation="MQKAIRLNDGHVVSLGLLAQRDGTRKGYLSKRSSDNPKWQTKWF
                     ALLQNLLFYFESDSSSRPSGLYLLEGSICKRMPSPKRGTSSKESDKQHHYFTVNFSND
                     SQKSLELRTDDSKDCDEWVAAIARASYKILATEHEALMQKYLHLLQVVETEKTVAKQL
                     RQQLEDGEVEIERLKAEIANLIKDNERIQSNQLVAPEDEDSDIKKIKKVQSFLRGWLC
                     RRKWKNIIQDYIRSPHADSMRKRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASS
                     KKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARIASWPTLVLADLFDILLPMLNIYQ
                     EFVRNHQYSLQILAHCKQNRDFDKLLKQYEAKPDCEERTLETFLTYPMFQIPRYILTL
                     HELLAHTPHEHVERNSLDYAKSKLEELSRVMHDEVSETENIRKNLAIERMITEGCEIL
                     LDTSQTFVRQGSLIQVPMSEKGKINKGRLGSLSLKKEGERQCFLFSKHLIICTRGSGS
                     KLHLTKNGVISLIDCTLLDDPENMDDDGKGQEVDHLDFKIWVEPKDSPPFTVILVASS
                     RQEKAAWTSDIIQCVDNIRCNGLMMNAFEENSKVTVPQMIKSDASLYCDDVDIRFSKT
                     MNSCKVLQIRYASVERLLERLTDLRFLSIDFLNTFLHSYRVFTDAVVVLDKLISIYKK
                     PITAIPARSLELLFSSSHNTKLLYGDAPKSPRASRKFSSPPPLAIGTSSPVRRRKLSL
                     NIPIITGGKALELASLGCPSDGYTNIHSPISPFGKTTLDTSKLCVASSLTRTPEEIDM
                     TTLEESSGFRKPTSDILKEESDDDQSDVDDTEVSPPTPKSFRNRITQEFPLFNYNSGI
                     MMTCRDLMDSNRSPLSATSAFAIATAGANESPANKEIYRRMSLANTGYSSDQRNIDKE
                     FVIRRAATNRVLNVLRHWVTKHSQDFETDDLLKYKVICFLEEVMHDPDLLPQERKAAA
                     NIMRTLTQEEITENHSMLDELLLMTEGVKTEPFENHSAMEIAEQLTLLDHLVFKSIPY
                     EEFFGQGWMKADKNERTPYIMKTTRHFNHISNLIASEILRNEEVSARASTIEKWVAVA
                     DICRCLHNYNAVLEITSSINRSAIFRLKKTWLKVSKQTKSLFDKLQKLVSSDGRFKNL
                     RETLRNCDPPCVPYLGMYLTDLAFLEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQ
                     TTYKIEPQPKVTQYLVDETFVLDDESLYEASLRIEPKLPT"
     misc_feature    238..461
                     /note="Db1 oncogene-like"
     misc_feature    920..1221
                     /note="S.cerevisiae CDC-25-like"
BASE COUNT     1015 a   1077 c    932 g    780 t
ORIGIN
        1 ccgacgaggg gcagtcgggt gcctctcgga gatgtttagt gcgtgaggtc tctctggcct
       61 ccaagcacca tgcagaaagc catccgactg aacgatggcc acgtcgtgtc cctgggactg
      121 ctggcccaga gagacggtac gcgcaaaggc tacctgagca agaggagttc ggacaaccca
      181 aaatggcaaa ccaagtggtt tgcgctgctg cagaacctgc tcttctactt cgaaagtgac
      241 tcgagctctc ggccctcggg gctctacctg ctggagggca gtatctgcaa acgcatgccc
      301 tcccccaagc gagggacctc ctccaaggag tccgacaaac agcatcatta cttcacagtg
      361 aacttctcca atgacagcca gaagtcccta gagctgagga ccgatgactc caaggactgt
      421 gacgagtggg tggcagcgat tgctcgcgcc agctacaaga tactggccac agagcatgag
      481 gcgctcatgc agaagtacct gcacctgctg caggtggtgg agacagagaa gaccgtggct
      541 aagcagctgc gacagcagct cgaggatggc gaggtcgaga tcgagcgcct gaaggcagag
      601 attgcaaacc tgatcaagga caatgaacgt atccagtcca accagctggt tgcccctgag
      661 gatgaggaca gtgacatcaa gaaaattaag aaggtacaga gtttccttcg cggatggctg
      721 tgccggcgaa agtggaagaa catcatccag gactacatcc ggtctcctca tgccgacagc
      781 atgcgcaaga ggaaccaggt ggtgttcagc atgctggaag ctgaggccga gtacgtgcag
      841 caactacaca tccttgtcaa caattttctg cgcccactgc gcatggccgc cagctctaag
      901 aaacccccta taacacatga cgacgtcagc agtatctttc tgaacagtga gaccatcatg
      961 ttcctgcacc agatcttcta ccaaggcctg aaggcccgta tcgccagctg gcccaccctg
     1021 gttctggcgg acctgttcga catcctgctg ccaatgctta acatctacca ggagttcgtc
     1081 cgcaaccacc agtacagtct ccagatccta gcacactgca agcaaaaccg ggactttgac
     1141 aagctcctca agcagtatga ggccaagcca gactgcgagg agcgcacact ggagaccttc
     1201 ctcacctatc caatgttcca gatccccagg tacatcctga cactccatga gctgctggcc
     1261 cacacacctc atgagcatgt ggagcgcaac agcctggact atgccaaatc caaactagag
     1321 gagctgtcca gggtcatgca cgacgaagtc agtgagaccg agaacatccg caaaaacctg
     1381 gccattgagc gtatgatcac cgagggctgt gagatcctcc ttgacaccag ccagaccttt
     1441 gtgcgccaag gttccctcat ccaggtgccc atgtcagaaa agggcaagat caacaagggc
     1501 cgcctggggt ctctgtccct taagaaagaa ggtgagcgcc agtgtttcct gttctccaag
     1561 catctcatca tctgcaccag aggctctggt agcaaactgc acctaaccaa gaatggcgtg
     1621 atttccctca ttgactgcac tctactggat gatccagaaa acatggatga tgacggcaaa
     1681 ggacaagagg tagatcacct ggactttaag atttgggtgg agccaaagga ttccccaccc
     1741 ttcacagtca tcctggtggc ctcatccagg caggagaagg cggcatggac cagtgacatc
     1801 atccagtgcg tggataatat ccgctgcaac gggctcatga tgaatgcctt tgaagaaaat
     1861 tccaaggtca ccgtgccgca gatgatcaag tctgatgctt ccttatactg tgatgatgtt
     1921 gacattcgct tcagcaaaac catgaattct tgcaaagtgc tgcagatccg ctatgccagc
     1981 gtggagcgcc tgctggagcg cctgactgat cttcgcttcc tgagtattga ctttctcaac
     2041 accttcctgc actcctatcg agtcttcacc gatgctgtgg tggtcctaga caagctgatc
     2101 agcatctaca aaaagcccat cactgcgatt cctgccaggt cactggaact cctgttctcc
     2161 agtagccaca acaccaaact tctgtacgga gatgccccca agtcgcctcg tgccagccgc
     2221 aagttctcct cgccgccgcc cttggccatc ggcacttcgt ccccagtccg ccgccggaag
     2281 ttgtctctca acattcccat catcacaggc ggcaaggcgc tggaactggc ttcgctcggg
     2341 tgcccctccg acggctacac caacatacac tcgcccatat ctcccttcgg caaaaccacg
     2401 ctggacacca gcaagctctg tgtggccagc agcttgacca gaacgccgga ggagattgat
     2461 atgaccactc tagaggagtc atcaggcttc aggaagccga cctcagacat cttgaaagaa
     2521 gagtctgatg atgaccagag tgatgtagac gacacagaag tgtctccacc aacaccgaaa
     2581 tcattcagaa acagaatcac tcaagagttc ccactcttta actacaacag tggaatcatg
     2641 atgacatgtc gcgatctgat ggacagtaac cgcagccctc tgtcagctac ctctgccttt
     2701 gccatagcga ctgcaggagc caatgaaagc cccgcaaaca aggagatata tcgaaggatg
     2761 tctttggcca acacagggta ttcctctgac cagagaaata tcgacaaaga gttcgtgatc
     2821 cgcagagcgg ccaccaaccg tgtactgaat gtgttgcgcc actgggtcac caagcactcc
     2881 caggactttg aaactgacga cctcctcaaa tacaaggtga tctgctttct ggaagaggtc
     2941 atgcatgacc cagaccttct accacaagag cgaaaggcag cagccaacat catgaggact
     3001 ctgacccagg aagaaataac tgaaaaccat agcatgctgg atgagctctt actaatgacg
     3061 gagggtgtga agactgagcc cttcgaaaac cactcagcca tggagatagc agagcagctg
     3121 accctgctgg atcaccttgt cttcaagagt attccttatg aggaattctt tggccagggc
     3181 tggatgaagg cagataagaa tgaaaggaca ccttacatta tgaaaaccac cagacatttc
     3241 aaccatatca gtaacttgat cgcttcagaa attctccgaa acgaggaggt cagtgcaagg
     3301 gcaagcacca tcgagaagtg ggtggctgtt gccgacattt gccgctgcct gcacaactac
     3361 aatgctgtgc tggagatcac ttcctccatc aaccgcagcg caatcttccg actcaagaag
     3421 acatggctca aagtttctaa gcagacgaaa tctctgtttg acaagctcca aaagcttgtg
     3481 tcatcagatg gccgatttaa gaacctcaga gaaactttgc gaaattgtga tccaccctgt
     3541 gtcccttacc tggggatgta cctgaccgac ttggcattcc tcgaggaagg aacacccaat
     3601 tacacagagg acggcctggt caacttctcc aagatgagga tgatctccca tattatccgc
     3661 gagattcgcc agtttcagca gactacttac aaaatcgagc cccagccaaa ggtaactcag
     3721 tacttagtgg atgaaacctt tgtgttggac gacgaaagtc tgtatgaggc ctccctccga
     3781 attgaaccaa aactccccac atga
//