From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens TCR V-beta 5.5 gene for TCR beta chain variable region
Date: 29 Aug 92 10:01:51 GMT
Distribution: bionet
Checksum: 60241     3

LOCUS       HUMTRVB55     741 bp ds-DNA             PRI       29-AUG-1992
DEFINITION  H.sapiens TCR V-beta 5.5 gene for TCR beta chain variable region
ACCESSION   X61439
KEYWORDS    T-cell receptor; T-cell receptor beta-chain variable region;
            TCR V-beta 5.5 gene.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Li,Y.
  JOURNAL   Unpublished (1991)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 739)
  AUTHORS   Li,Y., Szabo,P. and Posnett,D.N.
  TITLE     Human Tcr V beta 6.10 is a pseudogene with Alu repetitive sequences
            in the promoter region
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: tissue=placental; *source: clone_library=human genomic
            library; *source: clone=9; *source: isolate=human genomic library,
            Clontech labs., CAT# *source: HL1067J; *source: chromosome=7;
            *source: is_germline=Y;
            From EMBL    entry HSTRVB55;  dated 29-OCT-1991.
FEATURES             Location/Qualifiers
     CDS             join(236..284,409..700)
                     /partial
                     /note="V-beta-5.5"
                     /gene="TCRB"
                     /codon_start=1
                     /translation="MGPGLLCWELLYLLGAGPVEAGVTQSPTHLIKTRGQQVTLRCSP
                     ISGHSSVSWYQQAPGQGPQFIFEYANELRRSEGNFPNRFSGRQFHDCCSEMNVSALEL
                     GDSALYLCARS"
                     /partial
     promoter        1..235
                     /gene="TCRB"
     exon            236..284
                     /number=1
                     /note="first leader"
                     /gene="TCRB"
     intron          285..408
                     /number=1
                     /gene="TCRB"
     exon            409..700
                     /number=2
                     /note="second leader and V region"
                     /gene="TCRB"
BASE COUNT      165 a    217 c    191 g    168 t
ORIGIN
        1 aaactgtctt cattcacaga agcttctccc ttgtcaccct tctgctggac agggagggga
       61 gcttcaggtt gtggggagta ctggacctca ggaagtcctt tatagggagg acacaggaca
      121 gtgacatcac aggatatccc acccatcagg aaaatcaagg cccagaactc acttggccct
      181 tccccaggag gaccaagccc tgaatcagat gcagtgctgc ctgccccact gtgccatggg
      241 ccccgggctc ctctgctggg aactgcttta tctcctggga gcagatgagt cctgtgcaca
      301 gaacagcagc cccattctca gatttcccac ccctgtgtcc tccactttac actggggagg
      361 acctccaggc tgtctgctgt gctcatcctc catctgcttt tcccacaggc ccagtggagg
      421 ctggagtcac ccaaagtccc acacacctga tcaaaacgag aggacagcaa gtgactctga
      481 gatgctctcc tatctctggg cacagcagtg tgtcctggta ccaacaggcc ccgggtcagg
      541 ggccccagtt tatctttgaa tatgctaatg agttaaggag atcagaagga aacttcccta
      601 atcgattctc agggcgccag ttccatgact gttgctctga gatgaatgtg agtgccttgg
      661 agctggggga ctcggccctg tatctctgtg ccagaagctt ggcacagccc tgcagagtca
      721 ctggaactct gtgcactaat c
//