From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens FACC mRNA from complementation group C (FA(C))
Date: 29 Dec 92 01:19:33 GMT
Distribution: bionet
Checksum: 32294 9

LOCUS       HUMFACC1     4567 bp ss-RNA             PRI       07-DEC-1992
DEFINITION  H.sapiens FACC mRNA from complementation group C (FA(C))
ACCESSION   X66893 X66184
KEYWORDS    DNA-repair disorder.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 4567)
  AUTHORS   Buchwald,M.
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 4566)
  AUTHORS   Strathdee,C.A., Gavish,H., Shannon,W.R. and Buchwald,M.
  TITLE     Cloning of cDNAs for Fanconi's anemia by functional complementation
  JOURNAL   Nature 356, 763-767 (1992)
  STANDARD  full automatic
REFERENCE   3  (sites)
  AUTHORS   Strathdee,C.A., Duncan,A.M. and Buchwald,M.
  TITLE     evidence for at least four Fanconi anemia genes including FACC on
            chromosome 9
  JOURNAL   Nature Genet. 1, 196-198 (1992)
  STANDARD  full automatic
COMMENT     *source: stage=adult; *source: tissue=lymphoid; *source: cell_line=
            hsc93; *source: sex=F;


               From EMBL    entry HSFACC1;  dated 22-JUN-1992.
FEATURES             Location/Qualifiers
     5'UTR           1..255
     3'UTR           1929..4566
     polyA_signal    2319..2324
     polyA_site      2336
     polyA_signal    3121..3126
     polyA_site      3234
     repeat_region   3355..3477
     polyA_signal    4444..4449
     polyA_site      4566
     CDS             256..1929
                     /codon_start=1
                     /translation="MAQDSVDLSCDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEF
                     LRKMYEALKEMDSNTVIERFPTIGQLLAKACWNPFILAYDESQKILIWCLCCLINKEP
                     QNSGQSKLNSWIQGVLSHILSALRFDKEVALFTQGLGYAPIDYYPGLLKNMVLSLASE
                     LRENHLNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPE
                     FFEAVNEAILLKKISLPMSAVVCLWLRHLPSLEKAMLHLFEKLISSERNCLRRIECFI
                     KDSSLPQAACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFVEALEKASKQLR
                     FALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQTHGSCGGPFE
                     SWFLFIHFGGWAEMVAEQLLMSAAEPPTALLWLLAFYYGPRDGRQRAQTMVQVKAVLG
                     HLLAMSRSSSLSAQDLQTVAGQGTDTDLRAPAQQLIRHLLLNFLLWAPGGHTIAWDVI
                     TLMAHTAEITHEIIGFLDQTLYRWNRLGIESPRSEKLARELLKELRTQV"
BASE COUNT     1080 a   1133 c   1178 g   1176 t
ORIGIN      
        1 actgctgaca cgtgtgcgcg cgcgcggctc cactgccggg cgaccgcggg aaaattccaa
       61 aaaaactcaa aaagccaata cgaggcaaag ccaaattttc aagccacaga tcccgggcgg
      121 tggcttcctt tccgccactg cccaaactgc tgaagcagct cccgcgagga ccacccgatt
      181 taatgtgtgc cgaccatttc cttcagtgct ggacaggctg ctgtgaaggg acatcacctt
      241 ttcgcttttt ccaagatggc tcaagattca gtagatcttt cttgtgatta tcagttttgg
      301 atgcagaagc tttctgtatg ggatcaggct tccactttgg aaacccagca agacacctgt
      361 cttcacgtgg ctcagttcca ggagttccta aggaagatgt atgaagcctt gaaagagatg
      421 gattctaata cagtcattga aagattcccc acaattggtc aactgttggc aaaagcttgt
      481 tggaatcctt ttattttagc atatgatgaa agccaaaaaa ttctaatatg gtgcttatgt
      541 tgtctaatta acaaagaacc acagaattct ggacaatcaa aacttaactc ctggatacag
      601 ggtgtattat ctcatatact ttcagcactc agatttgata aagaagttgc tcttttcact
      661 caaggtcttg ggtatgcacc tatagattac tatcctggtt tgcttaaaaa tatggtttta
      721 tcattagcgt ctgaactcag agagaatcat cttaatggat ttaacactca aaggcgaatg
      781 gctcccgagc gagtggcgtc cctgtcacga gtttgtgtcc cacttattac cctgacagat
      841 gttgaccccc tggtggaggc tctcctcatc tgtcatggac gtgaacctca ggaaatcctc
      901 cagccagagt tctttgaggc tgtaaacgag gccattttgc tgaagaagat ttctctcccc
      961 atgtcagctg tagtctgcct ctggcttcgg caccttccca gccttgaaaa agcaatgctg
     1021 catctttttg aaaagctaat ctccagtgag agaaattgtc tgagaaggat cgaatgcttt
     1081 ataaaagatt catcgctgcc tcaagcagcc tgccaccctg ccatattccg ggttgttgat
     1141 gagatgttca ggtgtgcact cctggaaacc gatggggccc tggaaatcat agccactatt
     1201 caggtgttta cgcagtgctt tgtagaagct ctggagaaag caagcaagca gctgcggttt
     1261 gcactcaaga cctactttcc ttacacttct ccatctcttg ccatggtgct gctgcaagac
     1321 cctcaagata tccctcgggg acactggctc cagacactga agcatatttc tgaactgctc
     1381 agagaagcag ttgaagacca gactcatggg tcctgcggag gtccctttga gagctggttc
     1441 ctgttcattc acttcggagg atgggctgag atggtggcag agcaattact gatgtcggca
     1501 gccgaacccc ccacggccct gctgtggctc ttggccttct actacggccc ccgtgatggg
     1561 aggcagagag cacagactat ggtccaggtg aaggccgtgc tgggccacct cctggcaatg
     1621 tccagaagca gcagcctctc agcccaggac ctgcagacgg tagcaggaca gggcacagac
     1681 acagacctca gagctcctgc acaacagctg atcaggcacc ttctcctcaa cttcctgctc
     1741 tgggctcctg gaggccacac gatcgcctgg gatgtcatca ccctgatggc tcacactgct
     1801 gagataactc acgagatcat tggctttctt gaccagacct tgtacagatg gaatcgtctt
     1861 ggcattgaaa gccctagatc agaaaaactg gcccgagagc tccttaaaga gctgcgaact
     1921 caagtctaga aggcacgcag gccgtgtggg tgcccggcgt gagggatcag gctcgccagg
     1981 gccacaggac aggtgatgac ctgtggccac gcatttgtgg agtaagtgcc ctcgctgggc
     2041 tgtgagaatg agctgtacac atcttgggac aatctgctag tatctatttt acaaaatgca
     2101 gagccaggtc cctcagccca gactcagtca gacatgttca ctaatgactc aagtgagctt
     2161 cggtactcct ggtgcccgcc cggccagacc gtcagcttga taattactaa agcaaaggcc
     2221 tgggtgggag aacaggtttc tagtttttac ccaagtcaag ctgcacatct attatttaaa
     2281 aattcaaagt cttagaacca agaatttggt catgaaccat taaagaattt agagagaact
     2341 tagctctttt tagactcttt ttaggagtca gggatctggg ataaagccac actgtcttgc
     2401 tgtatggaga aattcttcaa ggggagtcag ggtccctcag gcttcccttg tgtctccctg
     2461 gacctgcctg acaggccaca ggagcagaca gcacacccaa gcccgggcct ccggcacact
     2521 ctttccactc tgtatttgct aaatgatgct aactgctacc aaaaggccct tgggacatca
     2581 gaggagccgg cagcgaaggt agaggatgtg ttccagaaac attagaaggc aggattaatt
     2641 cagttagtta gtctcttgtt aaatggaaat gggaattgga aattcctgat aaagaattgg
     2701 cctggctggg tgcagtggct cacacctgtg atcccagcac tttgggaggc caaggcaggg
     2761 ggattacttc agcccaggag ttccagactg cctggctaac atggcaatac cctatctcta
     2821 ctaaaaatac aaaaattatc ggggtgcaat ggcatgcatc tgtaacccag ctattcaaga
     2881 ggctgaggca tgaggatctc ttgaacccgg gaggtgggag ttgtagtgag ccgagatcat
     2941 gacactgcac tccagcctgg gcaacagagc gagaccatct cttaaaaaaa ggcattgtta
     3001 gtgtaactca aggttaacat ttatttcatg tcagtacagg gtgctttttc ctttcaggga
     3061 cattctggaa ttgtattggt tgtacattct tttgtgtcta ttctgtttgt caagtgagtc
     3121 aagacttgct tttgtccatt ttgatttgtg tgtattagtc tgagtcttgg ctccgttttg
     3181 aggtatgagc aaagttttgc tggatagagt taacctttag ggaaattcct tattttggta
     3241 tgtggcaatg ctaatagatc cactgaagat ctggaaaatt ccaggaactt tttcacctga
     3301 gcctttcttc tgagaaatgc tgcagtcaga agggtgtgct ggtaaagtat tttggtggca
     3361 gctgccatca tggtcattgc cttcatataa catgcttcgt gctcatggtc attgccttca
     3421 tataacatgc ttcgtgccat catgatcctt gccttcatat aacaaacatg cttcgtcaga
     3481 ggtgttgggg ttgaaaaagg agctgcatgc ttcactggag ttgagggcct ctcctgtctg
     3541 actttaagcc agaacttgtg gctgggccat ggaagctgtg actcctctgt ggacatggtg
     3601 gcagcaggga acccctagag agaggggcca ctgggaccag gcctcctgtt gtggagggac
     3661 tcctgggaca gtcctccacc ctgtcctgtg gtcctgtgta cagggttggc ctcttcctcc
     3721 tcccctgcca ggcctctgcc catgcccctt ccttccttct cctgggactg gtgaagctag
     3781 gcatctggaa gacttcttcc tagcctggaa gccctgacct cggcccatct gcagaatctc
     3841 ccagttcctt cacagctgcc gagtcctctc acgggtgcgg tggaggcggc cttgcggtgg
     3901 tgctttctgg gcagccaggg gttcctgggt gggaggactg tccctctggg gacgtggcac
     3961 tgaagtgcct gctggcttca tgtggccctt tgccctttcc cagcctgaga gatgctcaaa
     4021 ggtggggagc tgggggagcc acccctcggc cattccctcc acctccaaga caggtggcgg
     4081 ccgggcaggc actcttaagc ccacctcccc ctcttgttgc cttcgatttc ggcaaagcct
     4141 gggcaggtgc caccgggaag gaatggcatc gagatgctgg gcggggacgc ggcgtggcga
     4201 gggggcttga cggcgttggc ggggctgggc acaggggcag ccgcagggag gcagggatgg
     4261 caaggcgtga agccaccctg gaaggaactg gaccaaggtc ttcagaggtg cgacagggtc
     4321 tggaatctga ccttactcta gcaggagttt ttgtagactc tccctgatag tttagttttt
     4381 gataaagcat gctggtaaaa ccactaccct cagagagagc caaaaataca gaagaggcgg
     4441 agagcgcccc tccaaccagg ctgttattcc cctggactcc gtgacatctg tggaattttt
     4501 tagctcttta aaatctgtaa tttgttgtct attttttcat tctaaataaa acttcagttt
     4561 gcaccta
//