From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Homo sapiens sphingolipid activator proteins 1 and 2 processed
Date: 8 Apr 92 10:01:54 GMT
Distribution: bionet
Checksum: 36435     5

LOCUS       HUMSPHINO    2734 bp ss-mRNA            PRI       08-APR-1992
DEFINITION  Homo sapiens sphingolipid activator proteins 1 and 2 processed
            pseudogene mRNA, complete cds.
ACCESSION   M81355
KEYWORDS    pseudogene; sphingolipid activator protein.
SOURCE      Homo sapiens male infant skin cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2734)
  AUTHORS   Schnabel,D., Schroeder,M., Fuerst,W., Klein,A., Hurwitz,R.,
            Zenk,T., Weber,J., Harzer,K., Paton,B., Poulos,A., Suzuki,K. and
            Sandhoff,K.
  TITLE     Simultaneous deficiency of sphingolipid activator proteins 1 and 2
            is caused by a mutation in the initiation codon of their common
            gene
  JOURNAL   J. Biol. Chem. 267, 3312-3315 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             9..1592
                     /pseudo
                     /note="start codon atg->ttg resulting in no synthesis of
                     the coding region"
                     /gene="sphingolipid activator protein"
                     /codon_start=1
BASE COUNT      586 a    697 c    784 g    667 t
ORIGIN
        1 ccggcgcttt gtacgccctc ttcctcctgg ccagcctcct gggcgcggct ctagccggcc
       61 cggtccttgg actgaaagaa tgcaccaggg gctcggcagt gtggtgccag aatgtgaaga
      121 cggcgtccga ctgcggggca gtgaagcact gcctgcagac cgtttggaac aagccaacag
      181 tgaaatccct tccctgcgac atatgcaaag acgttgtcac cgcagctggt gatatgctga
      241 aggacaatgc cactgaggag gagatccttg tttacttgga gaagacctgt gactggcttc
      301 cgaaaccgaa catgtctgct tcatgcaagg agatagtgga ctcctacctc cctgtcatcc
      361 tggacatcat taaaggagaa atgagccgtc ctggggaggt gtgctctgct ctcaacctct
      421 gcgagtctct ccagaagcac ctagcagagc tgaatcacca gaagcagctg gagtccaata
      481 agatcccaga gctggacatg actgaggtgg tggccccctt catggccaac atccctctcc
      541 tcctctaccc tcaggacggc ccccgcagca agccccagcc aaaggataat ggggacgttt
      601 gccaggactg cattcagatg gtgactgaca tccagactgc tgtacggacc aactccacct
      661 ttgtccaggc cttggtggaa catgtcaagg aggagtgtga ccgcctgggc cctggcatgg
      721 ccgacatatg caagaactat atcagccagt attctgaaat tgctatccag atgatgatgc
      781 acatgcagga tcagcaaccc aaggagatct gtgcgctggt tgggttctgt gatgaggtga
      841 aagagatgcc catgcagact ctggtccccg ccaaagtggc ctccaagaat gtcatccctg
      901 ccctggaact ggtggagccc attaagaagc acgaggtccc agcaaagtct gatgtttact
      961 gtgaggtgtg tgaattcctg gtgaaggagg tgaccaagct gattgacaac aacaagactg
     1021 agaaagaaat actcgacgct tttgacaaaa tgtgctcgaa gctgccgaag tccctgtcgg
     1081 aagagtgcca ggaggtggtg gacacgtacg gcagctccat cctgtccatc ctgctggagg
     1141 aggtcagccc tgagctggtg tgcagcatgc tgcacctctg ctctggcacg cggctgcctg
     1201 cactgaccgt tcacgtgact cagccaaagg acggtggctt ctgcgaagtg tgcaagaagc
     1261 tggtgggtta tttggatcgc aacctggaga aaaacagcac caagcaggag atcctggctg
     1321 ctcttgagaa aggctgcagc ttcctgccag acccttacca gaagcagtgt gatcagtttg
     1381 tggcagagta cgagcccgtg ctgatcgaga tcctggtgga ggtgatggat ccttccttcg
     1441 tgtgcttgaa aattggagcc tgcccctcgg cccataagcc cttgttggga actgagaagt
     1501 gtatatgggg cccaagctac tggtgccaga acacagagac agcagcccag tgcaatgctg
     1561 tcgagcattg caaacgccat gtgtggaact aggaggagga atattccatc ttggcagaaa
     1621 ccacagcatt ggtttttttc tacttgtgtg tctgggggaa tgaacgcaca gatctgtttg
     1681 actttgttat aaaaataggg ctcccccacc tcccccattt ctgtgtcctt tattgtagca
     1741 ttgctgtctg caagggagcc cctagcccct ggcagacata gctgcttcag tgcccctttt
     1801 ctctctgcta gatggatgtt gatgcactgg aggtctttta gcctgccctt gcatggcgcc
     1861 tgctggagga ggagagagct ctgctggcat gagccacagt ttcttgactg gaggccatca
     1921 accctcttgg ttgaggcctt gttctgagcc ctgacatgtg cttgggcact ggtgggcctg
     1981 ggcttctgag gtggcctcct gccctgatca gggaccctcc ccgctttcct gggcctctca
     2041 gttgaacaaa gcagcaaaac aaaggcagtt ttatatgaaa gattagaagc ctggaataat
     2101 caggcttttt aaatgatgta attcccactg taatagcata gggattttgg aagcagctgc
     2161 tggtggcttg ggacatcagt ggggccaagg gttctctgtc cctggttcaa ctgtgatttg
     2221 gctttcccgt gtctttcctg gtgatgcctt gtttggggtt ctgtgggttt gggtgggaag
     2281 agggccatct gcctgaatgt aacctgctag ctctccgaag gccctgcggg cctggcttgt
     2341 gtgagcgtgt ggacagtggt ggccgcgctg tgcctgctcg tgttgcctac atgtccctgg
     2401 ctgttgaggc gctgcttcag cctgcacccc tcccttgtct catagatgct ccttttgacc
     2461 ttttcaaata aatatggatg gcgagctcct aggcctctgg cttcctggta gagggcggca
     2521 tgccgaaggg tctgctgggt gtggattgga tgctggggtg tgggggttgg aagctgtctg
     2581 tggcccactt gggcacccac gcttctgtcc acttctggtt gccaggagac agcaagcaaa
     2641 gccagcagga catgaagttg ctattaaatg gacttcgtga tttttgtttt gcactaaagt
     2701 ttctgtgatt taacaataaa attctgttag ccag
//