From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse MHC class III RD gene (H2-d and H2-Sk haplotypes), complete
Date: 31 Dec 92 01:31:00 GMT
Distribution: bionet
Checksum: 02193 5

LOCUS       MUSMHRDDK    1812 bp ds-DNA             ROD       16-DEC-1992
DEFINITION  Mouse MHC class III RD gene (H2-d and H2-Sk haplotypes), complete
            cds.
ACCESSION   M21332
KEYWORDS    RD protein; class III gene; major histocompatibility complex.
SOURCE      Mouse H2-d haplotype, DNA, clone WL10S and mouse H2-Sk haplotype
            liver, cDNA to mRNA, clone WL623.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1812)
  AUTHORS   Levi-Strauss,M., Carroll,M.C., Steinmetz,M. and Meo,T.
  TITLE     A previously undetected MHC gene with an unusual periodic structure
  JOURNAL   Science 240, 201-204 (1988)
  STANDARD  full automatic
COMMENT     Authors named the 42 kd polypeptide product RD for the most common
            dipeptide repeat.  Both haplotypes had identical sequences for the
            exons.
FEATURES             Location/Qualifiers
     misc_feature    1..451
                     /note="This feature applies to a gene which lacks a coding
                     region feature. "
                     /gene="RD"
     exon            <1..131
                     /number=1
                     /gene="RD"
     intron          132..451
                     /number=1
                     /gene="RD"
     CDS             460..1587
                     /note="42 kd polypeptide;  (RD), (first expressed exon)"
                     /codon_start=1
                     /translation="MLVIPPGLSEEEEALQKEFNKLKKKKKALLALKKQSSSGPASQG
                     GVKRSLSEQPVVDTATATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKG
                     PVPTFQPFQRSMSADEDLQEPSRRPQRKSLYESFVSSSDRLRELGQDGEEAEAPGAGD
                     GPPRGFDWSYEEHGSARSSASPPRSRSRDRSHDRSRDRDRDKERDRDRDRDRDRDRDK
                     DKDRDRDRDRDKERDRDRDRDRDRERDREGPFRRSDSFPERRAPRKGNTLYVYGEDMT
                     PTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKVNIA
                     RKQPMLDAATGKSVWGSLAVQNSPKGCHRDKRTQIVYSDDL"
BASE COUNT      445 a    478 c    542 g    347 t
ORIGIN      506 bp upstream of PstI site; chromosome 17.
        1 ctcaggtgag ggcttcgtct cacatctttc gcgccttccc cgcgcggccc ctggttcttc
       61 ttcctcctcc tctggttgcc cagatagcgc tacgcgggcc cggccgcctt ctctgcccat
      121 cggaccccga ggttggctga cctaacccca ttgggcatgg gggtcgggag ccatcgcctt
      181 ggcgtcgcag gatgctttcc cttctccggg ctgaggtacc ccaaggctct agtgtctgga
      241 ccttggacat aggcgggaat gccggttgat taccatgacc aggaggctgg acaagcagcc
      301 tcggaggaac gaggggttag ggaaaggcca gaggctggag taggcgggcc tggaggttgg
      361 ggtgcataca ggatggacgc aagttggacg acgtgtgaat tttgaatggt gacagtagag
      421 aatgatgtct tgggttctgc ccttgaacca ggagccaaca tgttggtgat acctccgggg
      481 ctgagtgaag aggaagaggc actgcagaag gagttcaaca aactcaagaa gaagaaaaag
      541 gcattgctgg ctctgaagaa gcagagcagc agcggcccag cgagccaggg cggtgtcaaa
      601 cgctcactgt cagagcagcc tgtggtggac actgccacag caacagaaca ggccaaacaa
      661 ctggtgaagt caggagccat cagtgccatc aaggctgaaa ctaagaactc aggcttcaaa
      721 cgttctcgga ccctggaagg gaagttaaag gacccagaga aggggcctgt ccccactttc
      781 cagccgttcc agaggagcat gtctgctgat gaggacctac aggagccatc cagacgtccc
      841 cagaggaaat ctctgtatga aagctttgtg tcttctagtg atcggcttcg ggaactggga
      901 caagatggag aagaagcaga ggcccccggg gctggtgatg gcccacctcg aggctttgac
      961 tggagctatg aagagcatgg tagcgcccgc tcctcagcct cccctccccg aagccgcagc
     1021 agggaccgaa gtcatgaccg gagccgagat agggatcggg acaaagagag agacagagac
     1081 cgagatcgag atcgagacag agaccgggat aaagacaaag acagagaccg ggatcgagac
     1141 agagacaaag agcgggatcg agacagagac cgggaccgag atcgggaacg agaccgagag
     1201 ggccctttcc gcaggtcaga ctcattcccc gaacggaggg cccctcgaaa ggggaacaca
     1261 ctgtatgtgt atggagagga catgacgccc accctcctcc gcggggcctt ctctcccttt
     1321 ggaaatatca tcgacctctc catggaccca cccagaaact gtgccttcgt cacctacgag
     1381 aagatggagt ctgcagatca ggctgttgct gagctcaatg ggacccaggt ggaatctgtg
     1441 cagcttaaag tcaacatagc ccgaaaacag cccatgctgg acgctgctac tggcaaatct
     1501 gtctggggct cccttgctgt ccagaacagc cctaagggtt gccatcgaga caagaggacc
     1561 cagattgtgt acagtgacga tctataggaa accttgtgga tggcttctag gacatgaagc
     1621 tggattcctt gtgcctcata tgcccccaag ctggtctcag taaaatcctg gggtagaagc
     1681 ttttcacctc cgtcagcctc tagtctttca gcacttggga ttggagttaa gccttcaaaa
     1741 gcggctgtca gtgttgatgt taaccagtgc acgcccttac cccaaaaaga tgtggaacac
     1801 acttgttatt gt
//