From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mus musculus delta-5-3-beta-hydroxysteroid dehydrogenase/delta-5->
Date: 10 Apr 92 10:08:27 GMT
Distribution: bionet
Checksum: 48945     5

LOCUS       MUSHSD3B     1628 bp ss-mRNA            ROD       10-APR-1992
DEFINITION  Mus musculus delta-5-3-beta-hydroxysteroid dehydrogenase/delta-5->
            delta-4 isomerase (Hsd3b) mRNA, complete cds.
ACCESSION   M58567
KEYWORDS    delta-5-3-beta-hydroxysteroid dehydrogenase/delta-5-> delta-4 ise.
SOURCE      Mouse (strain CD-1), cDNA to mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Bain,P.A., Yoo,M., Clarke,T., Hammond,S.H. and Payne,A.H.
  TITLE     Multiple forms of mouse 3 beta - hydroxysteroid dehydrogenase /
            delta 5 - delta 4 isomerase and differential expression in gonads,
            adrenal glands, liver, and kidneys of both sexes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 88, 8870-8874 (1991)
  STANDARD  simple staff_entry
FEATURES             Location/Qualifiers
     mat_peptide     131..1249
                     /EC_number="1.1.1.145"
                     /standard_name="3bHSD/isomerase"
                     /product="3-beta-hydroxysteroid
                     dehydrogenase/delta-5-steroid isomerase"
                     /gene="Hsd3b"
                     /codon_start=1
     CDS             131..1252
                     /EC_number="1.1.1.145"
                     /standard_name="3bHSD/isomerase"
                     /product="3-beta-hydroxysteroid
                     dehydrogenase/delta-5-steroid isomerase"
                     /gene="Hsd3b"
                     /codon_start=1
                     /translation="MAGWSCLVTGAGGFVGQRIIKMLVQEKELQEVRALDKVFRPETK
                     EEFSKLQTKTKVTVLEGDILDAQCLRRACQGISVVIHTAAVIDVTGVIPRQTILDVNL
                     KGTQNLLEACVQASVPAFIFCSSVDVAGPNSYKKIVLNGHEEQNHESTWSDPYPYSKK
                     MAEKAVLAANGSMLKNGGTLNTCALRPMYIYGERSPFIFNAIIRALKNKGILCVTGKF
                     SIANPVYVENVAWAHILAARGLRDPKKSTSIQGQFYYISDDTPHQSYDDLNYTLSKEW
                     GLRPNASWSLPLPLLYWLAFLLETVSFLLRPVYRYRPLFNRHLITLSNSTFTFSYKKA
                     QRDLGYEPLVNWEEAKQKTSEWIGTIVEQHREILDTKCQ"
BASE COUNT      472 a    396 c    372 g    388 t
ORIGIN
        1 agtcctgatc tgagggctga ggagatcagc atccagacac tctcatctga cttttaacaa
       61 tttaacagcc ctcctaaggg ttaccctata tcataccagc tcccactgtc atctgtttcc
      121 tgtgttgacc atggctggat ggagctgcct ggtgacagga gcaggagggt ttgtgggcca
      181 gaggatcatc aagatgttgg tgcaggagaa agaactgcag gaggtcagag ctctggacaa
      241 agtattccga ccagaaacca aggaggaatt ctccaagctg cagacaaaga ccaaggtgac
      301 agtgttggaa ggagacattc tggatgccca gtgcctgagg agagcctgcc agggcatctc
      361 tgttgtcatc cacactgctg ctgtcattga tgtcacaggt gtcattccca ggcagaccat
      421 cctagatgtc aatctgaaag gtacccagaa cctattggag gcctgtgttc aagcaagtgt
      481 gccagccttc atcttctgca gctcagttga tgttgcaggg cccaactcgt acaagaagat
      541 cgtcctgaat ggccacgagg aacagaatca tgaaagcaca tggtctgatc catacccata
      601 cagcaaaaag atggctgaga aggcagtact ggcagccaat gggagcatgc tgaaaaatgg
      661 tggcactttg aatacttgtg ccttaagacc catgtacatt tatggggaga gaagtccatt
      721 catttttaat gcaataatta gggccctcaa aaataagggt attctgtgtg ttactggcaa
      781 attctccata gccaacccag tatatgtgga aaatgtggcc tgggcacaca ttctggcagc
      841 caggggcctt cgagacccca agaagtctac aagcatccaa ggacagttct actacatctc
      901 agatgacacc cctcaccaaa gctatgatga tttaaattac accctaagta aggaatgggg
      961 gctccgccct aatgccagct ggagccttcc tctgcccctg ctctactggc ttgccttcct
     1021 gctggaaact gtgagcttcc tgctacgtcc agtctacagg tatagacctc tctttaaccg
     1081 ccacttgatc acactgtcaa atagcacgtt cactttttct tacaagaaag ctcagcgaga
     1141 tctgggctat gagccacttg tcaactggga ggaagcaaag cagaaaacct cagagtggat
     1201 agggacaata gtggaacagc acagggagat actggacaca aagtgccagt gatggaaaaa
     1261 gggcaggtac atggctctgg gagttataag gtcctgtagc aagtacagag gcacaagcca
     1321 ggtcctgctg tctcctgtag acacagagac caacttggta tctttctcaa gtcaccagaa
     1381 gccttgccag tcactaaccc actcacaaac ttgcttccct aagcccctgc tcagagacaa
     1441 acatagctga gtctcagttc ttaggcttca gcaattacaa tttactttca cttagaactt
     1501 agtattgctt ttatttcccc cttcaagtcc taaatcatat cctgcctttg gtaaaatccc
     1561 attgctttct gaagcaaaac aaaaacagca ataaatattg taatgcctta aaaaaaaaaa
     1621 aaaaaaaa
//