From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human angiotensin II type-1 receptor (AT1) mRNA, complete cds.
Date: 6 Nov 92 18:06:18 GMT
Distribution: bionet
Checksum: 44003 4

LOCUS       HUMANTIIR    1575 bp ss-mRNA            PRI       28-OCT-1992
DEFINITION  Human angiotensin II type-1 receptor (AT1) mRNA, complete cds.
ACCESSION   M93394
KEYWORDS    angiotensin II type-1 receptor.
SOURCE      Homo sapiens cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Curnow,K.M., Pascoe,L. and White,P.C.
  TITLE     Genetic Analysis of the human type-1 angiotensin II receptor
  JOURNAL   Mol. Endocrinol. 6, 1113-1118 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..172
                     /gene="AT1"
     misc_feature    42..125
                     /note="Unprocessed intron, use of an alternate splice
                     donor site or additional 5' untranslated exon; present in
                     about half of all transcripts in most tissues expressing
                     AT1."
                     /gene="AT1"
     3'UTR           1253..1575
                     /gene="AT1"
     CDS             173..1252
                     /gene="AT1"
                     /product="angiotensin II type-1 receptor"
                     /codon_start=1
                     /translation="MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIF
                     GNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCK
                     IASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLAS
                     LPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLI
                     WKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRI
                     ADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKM
                     STLSYRPSDNVSSSTKKPAPCFEVE"
BASE COUNT      440 a    339 c    302 g    494 t
ORIGIN      
        1 gccggccctc ggcgggacgt gacgcagcgc ccggggcgcg ggtttgatat ttgacaaatt
       61 gatctaaaat ggctgggttt ttatctgaat aactcactga tgccatccca gaaagtcggc
      121 accaggtgta tttgatatag tgtttgcaac aaattcgacc caggtgatca aaatgattct
      181 caactcttct actgaagatg gtattaaaag aatccaagat gattgtccca aagctggaag
      241 gcataattac atatttgtca tgattcctac tttatacagt atcatctttg tggtgggaat
      301 atttggaaac agcttggtgg tgatagtcat ttacttttat atgaagctga agactgtggc
      361 cagtgttttt cttttgaatt tagcactggc tgacttatgc tttttactga ctttgccact
      421 atgggctgtc tacacagcta tggaataccg ctggcccttt ggcaattacc tatgtaagat
      481 tgcttcagcc agcgtcagtt tcaacctgta cgctagtgtg tttctactca cgtgtctcag
      541 cattgatcga tacctggcta ttgttcaccc aatgaagtcc cgccttcgac gcacaatgct
      601 tgtagccaaa gtcacctgca tcatcatttg gctgctggca ggcttggcca gtttgccagc
      661 tataatccat cgaaatgtat ttttcattga gaacaccaat attacagttt gtgctttcca
      721 ttatgagtcc caaaattcaa cccttccgat agggctgggc ctgaccaaaa atatactggg
      781 tttcctgttt ccttttctga tcattcttac aagttatact cttatttgga aggccctaaa
      841 gaaggcttat gaaattcaga agaacaaacc aagaaatgat gatattttta agataattat
      901 ggcaattgtg cttttctttt tcttttcctg gattccccac caaatattca cttttctgga
      961 tgtattgatt caactaggca tcatacgtga ctgtagaatt gcagatattg tggacacggc
     1021 catgcctatc accatttgta tagcttattt taacaattgc ctgaatcctc ttttttatgg
     1081 ctttctgggg aaaaaattta aaagatattt tctccagctt ctaaaatata ttcccccaaa
     1141 agccaaatcc cactcaaacc tttcaacaaa aatgagcacg ctttcctacc gcccctcaga
     1201 taatgtaagc tcatccacca agaagcctgc accatgtttt gaggttgagt gacatgttcg
     1261 aaacctgtcc ataaagtaat tttgtgaaag aaggagcaag agaacattcc tctgcagcac
     1321 ttcactacca aatgagcatt agctactttt cagaattgaa ggagaaaatg cattatgtgg
     1381 actgaaccga cttttctaaa gctctgaaca aaagcttttc tttccttttg caacaagaca
     1441 aagcaaagcc acattttgca ttagacagat ggacggctgc tcgaagaaca atgtcagaaa
     1501 ctcgatgaat gtgttgattc gagaaatttt actgacagaa atgcaatctc cctagcctgc
     1561 ttttgtcctg ttatt
//