From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: D.pseudoobscura Adh gene for alcohol dehydrogenase
Date: 28 Dec 92 21:26:23 GMT
Distribution: bionet
Checksum: 41850 8

LOCUS       DROADHGN09   3457 bp ds-DNA             INV       01-DEC-1992
DEFINITION  D.pseudoobscura Adh gene for alcohol dehydrogenase
ACCESSION   X62189
KEYWORDS    ADH gene; alcohol dehydrogenase.
SOURCE      Drosophila pseudoobscura DNA.
  ORGANISM  Drosophila pseudoobscura
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 3457)
  AUTHORS   Schaeffer,S.W. and Miller,E.L.
  TITLE     Estimates of gene flow in Drosophila pseudoobscura determined from
            nucleotide sequence analysis of the alcohol dehydrogenase region
  JOURNAL   Genetics 132, 471-480 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=BR7F; *source: isolate=Bryce Canyon, Utah; *source:
            chromosome=IV section 88;
               From EMBL    entry DPADHGN09;  dated 16-OCT-1992.
FEATURES             Location/Qualifiers
     mRNA            join(40..119,917..1022,1086..1490,1551..1966)
                     /note="adult mRNA (Adh)"
     mRNA            join(884..1022,1086..1490,1551..1966)
                     /note="larval mRNA (Adh)"
     promoter        8..14
                     /note="adult promoter (Adh)"
     prim_transcript 40..1966
                     /note="adult primary transcript (Adh)"
     exon            40..119
                     /note="adult exon 1a"
     intron          120..916
                     /note="adult intron"
     promoter        848..855
                     /note="larval promoter (Adh)"
     prim_transcript 884..1966
                     /note="larval primary transcript (Adh)"
     exon            884..1022
                     /note="larval exon 1"
     exon            917..1022
                     /note="adult exon 1b"
     intron          1023..1085
                     /number=1
     exon            1086..1490
                     /number=2
     intron          1491..1550
                     /number=2
     exon            1551..1966
                     /number=3
     polyA_signal    1943..1948
     polyA_site      1966
     CDS             join(930..1022,1086..1490,1551..1817)
                     /EC_number="1.1.1.1"
                     /gene="Adh"
                     /product="alcoholdehydrogenase"
                     /codon_start=1
                     /translation="MSLTNKNVVFVAGLGGIGLDTSRELVKRNLKNLVILDRIDNPAA
                     IAELKAINPKVTITFYPYDVTVPVAETTKLLKTIFAQVKTIDVLINGAGILDDHQIER
                     TIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGSKAAVVN
                     FTSSLAKLAPITGVTAYTVNPGITKTTLVHKFNSWLDVEPRVAEKLLEHPTQTSQQCA
                     ENFVKAIELNKNGAIWKLDLGTLEPITWTQHWDSGI"
BASE COUNT      966 a    782 c    795 g    914 t
ORIGIN      
        1 cgtagtgtat ttaaggcact gcacatgtcg aggaccacga ttattgtcta cagtgcagtc
       61 agtagttgtc aggtgcagca ggcggatcaa catttcttta aatctactca atcgatcaag
      121 taagtaactg tgtaatccaa gtacagttgg cccatcccac tcggttctgc cgtaactcaa
      181 gaaatttctt gatagcgcag ttccagttgt agaacgtcgc ttaaaaaaac atctcgttgg
      241 agcttgggtt gaaaaacgtt cgagttgggc gtagaaaagt tcaaatataa aatatcaaaa
      301 aagagaaaat atcttcccaa agcagctgtc cattttttgt taaagtgata gatcaaaaat
      361 tcgtatgacg tatttcccaa gtgctcttta tgcaaataat ttcctcaatt ctaattctac
      421 aagaagcact tttggctctt gtccagaaaa aacaatttgt ttacactttt cggttgataa
      481 cagaggcgga ccgacggcta agtaacataa cagtcgcctg ttaagtaatg ccctcactct
      541 ctgttagatg gccgcgcgtg tcgactccga tagaccagca gacacgcagt agttttcctc
      601 aagaacctga actctaaaca tagacataat ttacgatacc ttgagactca aataaaaata
      661 caagtatgag tggtattcta ttcctgatta gactcgcaca cacacgcata cgagtattaa
      721 cataaatttg ccggcaaata accaaaacaa aacgaacgca aacgatccga acacgtaatg
      781 cgagagataa gaaacagaaa agctcgacgt gaaagaagct tctggcggaa gctcttgccg
      841 aactccctat aaatacgaga cagaaaacca gaataaatat aataacaaac tgttgaattg
      901 tcccatcgat tcccagatca aaagacagaa tgtctctcac caacaagaac gtcgttttcg
      961 tggccggtct gggcggcatt ggcctggaca ccagccggga gttggtcaag cgtaatctga
     1021 aggtaagagt gaacgaattc catggaatct atggaatcct aaatttaaaa atttatattt
     1081 tttagaacct ggtcatcctg gatcgcattg acaatccggc tgccattgcc gaactgaagg
     1141 caatcaatcc caaggtgacc atcaccttct atccctacga tgtgactgtg cccgtcgctg
     1201 agaccaccaa gctcctgaag accatctttg cccaggtgaa gaccatcgat gtgctgatca
     1261 acggtgctgg catcctggac gatcatcaga tcgagcgcac cattgccgtt aactacacgg
     1321 gcctggtcaa caccaccaca gccattctgg acttctggga caagcgcaag ggcggcccag
     1381 gcggcatcat ttgcaacatt ggctccgtca ccggtttcaa tgccatctac caggtgcccg
     1441 tttactccgg ctccaaggcg gcggtggtta actttacttc ctccctggcg gtaagaaatc
     1501 ctacaactat cctactcccc aaaactaaat atttctttga attcccatag aaactggctc
     1561 ccattactgg tgtcactgct tacactgtca atcctggcat cactaagacc actctggtcc
     1621 acaaattcaa ctcgtggctg gatgtggagc cccgtgtggc agagaagctg ctcgagcatc
     1681 ccacccagac ctctcagcag tgcgccgaga actttgtgaa ggccattgag ctgaacaaga
     1741 acggtgccat ctggaagttg gatttgggca ccttggagcc catcacatgg acccagcact
     1801 gggactcggg catctaaacc atcccagaga ctctatggga catggcgttt tagcttttag
     1861 tttctttttt tccactcaat tgttacgtat atacatacac atatggcaat aaggctgatt
     1921 tgaaccccgt tttgaatatg ataatacaaa attatatttg agaaatttca acaaaatcga
     1981 taagagctat agctctcttt taattaaaaa aaactagata aaaagagcaa tggtcagtgg
     2041 tggtgggcag tggtcgttgt ggcctctatc gatttccaca caaaaacttt actgtttagt
     2101 aatagaaaag aacttgagaa aggcagccaa aagaatgtac gatctgacgg gtaagcatgt
     2161 ctgctatgtg gctgactgcg gtggcattgc actggagacc agcaaggttc tcatgaccaa
     2221 gaatatagcg gtgagtggta gagtggtgta gagagtggag agtggttctg gttcttaaac
     2281 aagtctctag tctctagtct cttggctgct gctggtagct gtcgaaacta attaagttaa
     2341 tgactttttc atgttttgtt tttgtccgct gacttttgct gttcaaagct acaattaagt
     2401 ttatgttttg agtttgatct acttttgctt aagggaagta ctttcgatta cggattgctg
     2461 gcatataaaa atagatacca aggaatgtgc atcatatcat attgattcca tcttgattct
     2521 ttgcccagaa actggccatc cttcagagcg tggaaaaccc cccggccatt gctcagttac
     2581 aatcgattaa gcacagcaca cagatcttct tctggacctt cgatgtgacc atggcccgcg
     2641 aggagatgaa gaagtacttc gatgaggtca tggtccagat ggactacatc gatgtgctga
     2701 tcaatggggc caccctgtgc gatgagcgga acattgatgc caccatcaat acgaatctga
     2761 ccggcatgat gaacaccgtg gccactgtgc tgccctatat ggaccgtaag atgggcggtt
     2821 cggggggact gattgtgaat gtcacctccg tcataggact ggatccatcg ccggtctttt
     2881 gtgcgtacag tgcctcaaag tttggtgtga ttgggttcac ccgaagtcta gcggtgagtg
     2941 ggcgagatct taacttgaaa atcctctcta atgtctttca ttctttcgca ggatcccctg
     3001 tattacaccc aaaatggtgt ggctgtcatg gccgtctgct gtggtcccac caaagtgttt
     3061 gtcgatcgcg aactgactgc cttcctggaa tacggccaaa cctttgccga tcgcctgcgt
     3121 cgtgccccct gccaatcgac ggccgtctgc ggccagaata tagtaaatgc catcgagaga
     3181 tcggagaacg gacagatctg gattgccgac aagggcggcc tggagtcggt ggtcctccac
     3241 tggtattggc atatggccga tcagtttgtg aactatatgc agagcactga cgatgaggat
     3301 caggagtttt ttttgggcca gcgatgaggt ggaataaaac atcaaatgtg tcacaaaaag
     3361 taggcaactt gtttgtgggt ctgggaatag atttgaaata ttttgaggtc atatgaataa
     3421 tgacataaat gagggtgcct gaaagtatgc caagttt
//