From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human MHC class II lymphocyte antigen (HLA-DP) beta chain mRNA,
Date: 29 Dec 92 19:58:10 GMT
Distribution: bionet
Checksum: 42957 5

LOCUS       HUMMHHLADP   1501 bp ss-mRNA            PRI       10-DEC-1992
DEFINITION  Human MHC class II lymphocyte antigen (HLA-DP) beta chain mRNA,
            complete cds.
ACCESSION   M83664 M83129
KEYWORDS    HLA-DP beta chain; cell surface glycoprotein; class II gene;
            integral membrane protein; lymphocyte antigen-beta;
            major histocompatibility complex.
SOURCE      Homo sapiens (individual_isolate systemic lupus erythematosis (SLE)
            patient 0077) (library: SLE patient leucocyte) cDNA to mRNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1501)
  AUTHORS   Korioth,F., Hartung,K., Deicher,H. and Frey,J.
  TITLE     A new HLA-DPB1 allele from a patient with systemic lupus
            erythematosus
  JOURNAL   Tissue Antigens 39, 216-219 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     5'UTR           1..59
                     /gene="HLA-DPB1"
                     /partial
     sig_peptide     60..146
                     /gene="HLA-DPB1"
                     /codon_start=1
     mat_peptide     147..833
                     /product="HLA-DPB1"
                     /gene="HLA-DPB1"
                     /codon_start=1
     3'UTR           837..1501
                     /gene="HLA-DPB1"
                     /partial
     polyA_signal    1478..1483
                     /gene="HLA-DPB1"
                     /note="putative"
     polyA_site      1501
                     /gene="HLA-DPB1"
     CDS             60..836
                     /gene="HLA-DPB1"
                     /product="HLA-DPB1"
                     /codon_start=1
                     /translation="MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYVYQGRQEC
                     YAFNGTQRFLERYIYNREEYARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVP
                     DRVCRHNYELDEAVTLQRRVQPKVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFL
                     NGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYICQVEHTSLDSPVTVEWKAQ
                     SDSAQSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA"
BASE COUNT      385 a    372 c    368 g    376 t
ORIGIN      
        1 agcgagtcct tcttttcctg actgcagctc ttttcatttt gccatccttc tccagctcca
       61 tgatggttct gcaggtttct gcggcccccc ggacagtggc tctgacggcg ttactgatgg
      121 tgctgctcac atctgtggtc cagggcaggg ccactccaga gaattacgtg taccagggac
      181 ggcaggaatg ctacgcgttt aatgggacac agcgcttcct ggagagatac atctacaacc
      241 gggaggagta cgcgcgcttc gacagcgacg tgggggagtt ccgggcggtg acggagctgg
      301 ggcggcctgc tgcggagtac tggaacagcc agaaggacat cctggaggag aagcgggcag
      361 tgccggacag ggtatgcaga cacaactacg agctggacga ggccgtgacc ctgcagcgcc
      421 gagtccagcc taaggtgaac gtttccccct ccaagaaggg gcccctgcag caccacaacc
      481 tgcttgtctg ccacgtgaca gatttctacc caggcagcat tcaagtccga tggttcctga
      541 atggacagga ggaaacagct ggggtcgtgt ccaccaacct gatccgtaat ggagactgga
      601 ccttccagat cctggtgatg ctggaaatga ccccccagca gggagacgtc tacatctgcc
      661 aagtggagca caccagcctg gacagtcctg tcaccgtgga gtggaaggca cagtctgatt
      721 ctgcccagag taagacattg acgggagctg ggggcttcgt gctggggctc atcatctgtg
      781 gagtgggcat cttcatgcac aggaggagca agaaagttca acgaggatct gcataaacag
      841 ggttcctgac ctcaccgaaa agactaatgt gccttagaac aagcatttgc tgtgttttgt
      901 taacacctgg ttccaggaca gaccctcagc ttcccaagag gatactgctg ccaagaagtt
      961 gctctgaagt cagtttctat cgttctgctc tttgattcaa agcactgttt ctctcactgg
     1021 gcctccaacc atgttccctt cttcttagca ccacaaataa tcaaaaccca acataagtgt
     1081 ttgctttcct ttaaaaatat gcatcaaatc gtctctcatt acttttctct gagggtttta
     1141 gtaaacagta ggagttaata aagaagttca ttttggttta cacgtaggaa agaagagaag
     1201 catcaaagtg gagatatgtt aactattgta taatgtggcc tgttatacat gacactcttc
     1261 tgaattgact gtatttcagt gagctgcccc caaatcaagt ttagtgccct catccattta
     1321 tgtctcagac cgctattctt aactattcaa tggtgagcag actgcaaatc tgcctgatag
     1381 gacccatatt cccacagcac taattcaaca tatatcttac tgagagcatg ttttatcatt
     1441 accattaaga agttaaatga acatcagaat ttaaaatcat aaatataatc taatacactt
     1501 t
//