From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for HLA-E heavy chain (exons 4 - 7)
Date: 10 Apr 92 10:06:11 GMT
Distribution: bionet
Checksum: 19287     4

LOCUS       HUMHLAEHCM   1692 bp ss-mRNA            PRI       10-APR-1992
DEFINITION  H.sapiens mRNA for HLA-E heavy chain (exons 4 - 7)
ACCESSION   X64879
KEYWORDS    HLA-E gene.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1692)
  AUTHORS   Ulbrecht,M., Honka,T., Person,S. and Weiss,E.H.
  TITLE     The HLA-E gene encodes two differentially regulated transcripts and
            a cell suface protein
  JOURNAL   Unpublished (1992)
  STANDARD  full automatic
COMMENT     *source: haplotype=HLA-A2, B27, CW1; *source: stage=lymphoblastoid
            B cell; *source: tissue=B-LCL; *source: cell_line=LG2; *source:
            clone_library=LG2; *source: clone=LG2-E1; *source: isolate=B-LCL
            LG2; *source: chromosome=6;
            From EMBL    entry HSHLAEHCM;  dated 23-MAR-1992.
FEATURES             Location/Qualifiers
     exon            <1..56
                     /number=4
     CDS             <1..247
                     /product="HLA-E heavy chain"
                     /codon_start=2
                     /translation="YTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSG
                     AVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL"
     exon            57..173
                     /number=5
     exon            174..206
                     /number=6
     exon            207..>1692
                     /number=7
     polyA_signal    799..804
     polyA_signal    813..818
     polyA_signal    1670..1675
BASE COUNT      431 a    423 c    441 g    397 t
ORIGIN
        1 atacacgtgc catgtgcagc atgaggggct acccgagccc gtcaccctga gatggaagcc
       61 ggcttcccag cccaccatcc ccatcgtggg catcattgct ggcctggttc tccttggatc
      121 tgtggtctct ggagctgtgg ttgctgctgt gatatggagg aagaagagct caggtggaaa
      181 aggagggagc tactctaagg ctgagtggag cgacagtgcc caggggtctg agtctcacag
      241 cttgtaaagc ctgagacagc tgccttgtgt gcgactgaga tgcacagctg ccttgtgtgc
      301 gactgagatg caggatttcc tcacgcctcc cctatgtgtc ttaggggact ctggcttctc
      361 tttttgcaag ggcctctgaa tctgtctgtg tccctgttag cacaatgtga ggaggtagag
      421 aaacagtcca cctctgtgtc taccatgacc cccttcctca cactgacctg tgttccttcc
      481 ctgttctctt ttctattaaa aataagaacc tgggcagagt gcggcagctc atgcctgtaa
      541 tcccagcact tagggaggcc gaggagggca gatcacgagg tcaggagatc gaaaccatcc
      601 tggctaacac ggtgaaaccc cgtctctact aaaaaataca aaaaattagc tgggcgcaga
      661 ggcacgggcc tgtagtccca gctactcagg aggcggaggc aggagaatgg cgtcaacccg
      721 ggaggcggag gttgcagtga gccaggattg tgcgactgca ctccagcctg ggtgacaggg
      781 tgaaacgcca tctcaaaaaa taaaaattaa aaaataaaaa aagaacctgg atctcaattt
      841 aatttttcat attcttgcaa tgaaatggac ttgaggaagc taagatcata gctagaaata
      901 cagataattc cacagcacat ctctagcaaa tttagcctat tcctattctc tagcctattc
      961 cttaccacct gtaatcttga ccatatacct tggagttgaa tattgttttc atactgctgt
     1021 ggtttgaatg ttccctccaa cactcatgtt gagacttaat ccctaatgtg gcaatactga
     1081 aaggtggggc ctttgagatg tgattggatc gtaaggctgt gccttcattc atgggttaat
     1141 ggattaatgg gttatcacag gaatgggact ggtggcttta taagaagagg aaaagagaac
     1201 tgagctagca tgcccaaccc acagagagcc tccactagag tgatgctaag tggaaatgtg
     1261 aggtgcagct gccacagagg gcccccacca gggaaatgtc tagtgtctag tggatccagg
     1321 ccacaggaga gagtgccttg tggagcgctg ggagcaggac ctgaccacca ccaggacccc
     1381 agaactgtgg agtcagtggc agcatgcagc gcccccttgg gaaagcttta ggcaccagcc
     1441 tgcaacccat tcgagcagcc acgtaggctc gacccagcaa agccacaggc acggggctac
     1501 ctgaggcctt gggggccaat ccctgctcca gtgtgtccgt gaggcagcac acgaagtcaa
     1561 aagagattat ctcttcccac agataccttt tctctcccat gaccctttaa cagcatctgc
     1621 ttcattcccc tcaccttccc aggctgatct gaggtaaact ttgaagtaaa ataaaagctg
     1681 tgtttgagca tc
//