From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rattus norvegicus beta-adrenergic receptor kinase 1 (beta-ARK1)
Date: 3 Jan 93 22:08:33 GMT
Distribution: bionet
Checksum: 10736 6

LOCUS       RATBARK1     2683 bp ss-mRNA            ROD       21-DEC-1992
DEFINITION  Rattus norvegicus beta-adrenergic receptor kinase 1 (beta-ARK1)
            mRNA, complete cds.
ACCESSION   M87854
KEYWORDS    G protein-receptor kinase; beta-adrenergic receptor kinase 1.
SOURCE      Rattus norvegicus (strain Sprague-Dawley) (library: lambda-gt11)
            adult brain cDNA to mRNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2683)
  AUTHORS   Arriza,J.L., Dawson,T.M., Simerly,R.B., Martin,L.J., Caron,M.G.,
            Snyder,S.H. and Lefkowitz,R.J.
  TITLE     The G protein-receptor kinases beta-ARK1 and beta-ARK2 are widely
            distributed at synapses in rat brain
  JOURNAL   J. Neurosci. 12, 4045-4055 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             144..2213
                     /gene="beta-ARK1"
                     /product="beta-adrenergic receptor kinase 1"
                     /codon_start=1
                     /translation="MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQ
                     KYLEDRGEVTFEKIFSQKLGYLLFRDFYLNHLEEAKPLVEFYEEIEKYEKLETEEERV
                     VRSREIFDSYIMKELLACSHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGD
                     VFHKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYA
                     MKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNG
                     GDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRIS
                     DLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFR
                     QHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEIKES
                     PFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRN
                     FPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMS
                     KMGNPFLTQWQRRYFYLFPNRLEWRGEDEAPQSLLTMEEIQSVEETQIKERKCLLLKI
                     RGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLIQ
                     RGSANGL"
BASE COUNT      630 a    751 c    766 g    536 t
ORIGIN      
        1 gaattcgggc gggcgacgag cgaggaccgg gcggggcggc ggcggcgccg aggccgacaa
       61 gccgcgcggg ccgggccggg ccgagcgagc gggagcggag cggagcctcg ggcggcggga
      121 ggaacagcgc cgccgccgcc aagatggccg acctggaggc ggtactggcc gatgtgagct
      181 acctgatggc catggagaag agcaaggcca cgccggccgc gcgcgccagc aagaagatcc
      241 tgctgccaga gcccagcatc cgcagcgtca tgcagaagta tctagaggat cgaggagaag
      301 tgacctttga aaagatcttc tcacagaagt taggatacct gcttttccgg gacttctacc
      361 tgaaccatct ggaagaggcc aagcccttgg tggagttcta tgaagagatc gagaaatatg
      421 agaagctgga gacggaggag gaacgtgtgg tccgcagccg ggagatcttt gactcctaca
      481 tcatgaaaga actgctggcc tgctcacatc ccttttcaaa gaatgccacg gagcatgtcc
      541 agggccacct ggtgaagaag caggtacctc cagatctctt ccagccatac attgaggaga
      601 tttgtcagaa cctccgaggg gatgtgttcc acaaattcat tgagagtgac aagttcacac
      661 ggttctgcca gtggaagaat gtagagctca acatccacct gaccatgaat gacttcagtg
      721 tgcatcgaat catcgggcgt gggggcttcg gtgaggtcta tgggtgccgg aaagcagaca
      781 caggcaagat gtacgccatg aagtgtctgg acaagaaacg catcaagatg aagcagggag
      841 agaccctggc tctgaacgag cggatcatgc tttccctcgt cagcactggg gactgcccct
      901 tcatcgtgtg catgtcatat gcattccaca caccagacaa gctcagtttc atcctggatc
      961 tcatgaacgg tggggacctg cactaccact tgtctcagca tggagtcttc tctgaagccg
     1021 acatgcgctt ctacgcagct gagatcatcc tgggccttga acacatgcac aatcgctttg
     1081 tagtctacag ggacctaaag ccagccaaca ttctcctgga tgagcatggc catgtgagaa
     1141 tctcagacct gggcctagcc tgtgacttct ccaagaagaa gcctcatgcc agtgtgggca
     1201 cacacgggta catggccccg gaagtcctac agaagggcgt ggcctatgac agcagtgccg
     1261 actggttctc cctgggctgc atgctcttca agttgttgcg gggacacagc cccttccggc
     1321 agcacaagac caaagacaag catgagattg accgcatgac attgacaatg gctgttgagc
     1381 tgcctgactc cttctcccct gaactccgat ccctgctgga aggtttgctg cagagggatg
     1441 tcaatcggag actaggctgt ctgggccgtg gggctcaaga gataaaagaa agccccttct
     1501 tccgttccct ggactggcag atggtcttct tacagaagta ccctcctcca ctgatccccc
     1561 cacgcgggga ggtgaatgca gcggacgcct ttgacattgg ctcctttgat gaggaggaca
     1621 caaaaggaat caagttactg gacagtgacc aggaactgta ccgcaacttc cctctcacca
     1681 tctctgagcg gtggcaacag gaggtggcag agactgtctt tgataccatc aatgctgaga
     1741 cagaccggct ggaggcacgg aagaaagcca aaaacaaaca gctgggccac gaggaggact
     1801 acgccctggg taaggactgc atcatgcatg gctacatgtc caagatgggc aaccccttcc
     1861 tgacccagtg gcagcggcga tacttctacc tgttccccaa ccggcttgag tggaggggtg
     1921 aagacgaggc tccgcagagc ctcctgacca tggaagagat ccagtcggtg gaagagacac
     1981 agatcaagga acgcaagtgt ctcctgctta agatccgagg tggcaagcag tttgtcctgc
     2041 agtgtgatag tgaccctgag ctggtgcaat ggaaaaaaga gctgcgcgat gcttaccgtg
     2101 aggcccagca gctggtgcag cgagtgccca agatgaagaa caagccacgc tcacctgtgg
     2161 tggagctgag caaggtgcca ctgattcagc gtggcagtgc caacggcctc tgattcaccc
     2221 atctgctgcc cgcctgccca cccgcctttt ataaacctct aatttatttt gttgaatttt
     2281 tattatttgt tttcgcaaag cggaaaaggt tttattttgt aattattgtg atttcctgtg
     2341 gccccagcca ggcccagccc cagggagggg cctgcttgcc tcagctcctg ctgccaccaa
     2401 cccagccact gtctagcacc cctgccccgc ccccaccgca tgcccctagg gtccttgctc
     2461 ccagtatctt cctactggga agaggagcaa ccctcagcag ccctcttgcc cctccatggg
     2521 gtgaagccac agtcggtggg tgtgtcactt caggctctgt gggctacact cagcctgagg
     2581 cccagctggg tggcccagca cccctaccct aggaaggtgc aacacaggga tactacttga
     2641 actttcctat catagctccc atgccacaga gggacccgaa ttc
//