From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse Golli-mpb mRNA, complete cds (alternate transcript from clone
Date: 29 Dec 92 01:20:08 GMT
Distribution: bionet
Checksum: 60967 5

LOCUS       MUSGOLLIB    1407 bp ss-mRNA            ROD       07-DEC-1992
DEFINITION  Mouse Golli-mpb mRNA, complete cds (alternate transcript from clone
            BG21).
ACCESSION   L07508
KEYWORDS    alternative splicing; myelin basic protein; overlapping genes.
SOURCE      Mus musculus (strain C57BL/6) (library: gt11) 2 day brain cDNA to
            mRNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (sites)
  AUTHORS   Takahashi,N., Roach,A., Teplow,D.B., Prusiner,S.B. and Hood,L.E.
  TITLE     Cloning and characterization of the myelin basic protein gene from
            mouse: One gene can encode both 14 and 18.5 kd MBPs by alternate
            use of exons
  JOURNAL   Cell 42, 139-148 (1985)
  STANDARD  full automatic
REFERENCE   2  (sites)
  AUTHORS   de Ferra,F., Engh,H., Hudson,L., Kamholz,J., Puckett,C.,
            Molineaux,S. and Lazzarini,R.A.
  TITLE     Alternative splicing accounts for the four forms of myelin basic
            protein
  JOURNAL   Cell 43, 721-727 (1985)
  STANDARD  full automatic
REFERENCE   3  (sites)
  AUTHORS   Newman,S., Kitamura,K. and Campagnoni,A.T.
  TITLE     Identification of a cDNA coding for a fifth form of myelin basic
            protein in mouse
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 84, 886-890 (1987)
  STANDARD  full automatic
REFERENCE   4  (bases 1 to 1407)
  AUTHORS   Campagnoni,A.T., Pribyl,T., Campagnoni,C., Kampf,K.,
            Amur-Umarjee,S., Landry,C., Handley,V., Newman,S., Garbay,B. and
            Kitamura,K.
  TITLE     Structure and developmental regulation of Golli-mbp, a 105 Kb gene
            that overlaps the myelin basic protein gene and is expressed in
            cells in the oligodendrocyte lineage in the brain
  JOURNAL   J. Biol. Chem. (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             275..862
                     /standard_name="BG21 transcript"
                     /gene="Golli-mbp"
                     /evidence="EXPERIMENTAL"
                     /note="alternate"
                     /codon_start=1
                     /translation="MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSD
                     VFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGR
                     EDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQRSKYLATASTMDHARHGF
                     LPRHRDTGILDSIGRFFSGDRGAPKRGSGKVSSEP"
BASE COUNT      313 a    401 c    422 g    271 t
ORIGIN      
        1 gcgtttacct gctttcaagc actgggaggc ggggcgggag cggggtgcgc gcccgtcccc
       61 ggagcagccg ctgtcagtca ccgccgctgc gcgccaggga ggaccagcct ctggctcagg
      121 cggcctgagc ttcacgaccc cggaacatag tatccgcgcc ccagcgaccc ctagcccagc
      181 gttgggtccc atccgccggg atcccgggat cctgggcccc tcttggcctc cgagcagcag
      241 ccagcaccac tcttgaacac cccattgggt cgccatggga aaccactctg gaaagagaga
      301 attatctgct gagaaggcca gtaaggatgg agagattcac cgaggagagg ctggaaagaa
      361 gagaagcgtg ggcaagcttt ctcagacggc ctcagaggac agtgatgtgt ttggggaggc
      421 agatgcgatc cagaacaatg ggacctcggc tgaggacacg gcggtgacag actccaagca
      481 cacagcagac ccaaagaata actggcaagg cgcccaccca gctgacccag ggaaccgccc
      541 ccacttgatc cgcctctttt cccgagatgc cccgggaagg gaggacaaca ccttcaaaga
      601 caggccctca gagtccgacg agcttcagac catccaagaa gaccccacag cagcttccgg
      661 aggcctggat gtgatggcat cacagaagag accctcacag cgatccaagt acctggccac
      721 agcaagtacc atggaccatg ccaggcatgg cttcctccca aggcacagag acacgggcat
      781 ccttgactcc atcgggcgct tctttagcgg tgacaggggt gcgcccaagc ggggctctgg
      841 caaggtgagc tccgagccgt agagaagctg tgggtttaaa tgcggaaagg aaggagaggt
      901 gggcaggtgg aactgggcca gtcaccatcg cagagcaacc gtgtccctgt gtctgagata
      961 ctagccctga tcggacagtg ctgatggcct gggggattgg gcgtggagtg ggcgtggtcg
     1021 ccacttagcc aatttctact tgttttgctc ctttgtcctt ctcacaggga ctgcgattgg
     1081 gtgtcactca ggaatgcaat gccttctgca tcctaacttg aggcacccag gatgtagcat
     1141 tgagcctatg ggttcctagg tatacatgcc ctatgcctgg gcttcagcag atcctgcctc
     1201 tgcgcagtgc ttccgggttt cgaacctcag ctgtgctcat tctctgctgg gtacaggctg
     1261 ctaattgctt gccgctgtga aacaatggtc caattgaggc gaggaggtct gccgactgac
     1321 ctctgcacct ccagcaaact ttcctctttg tcctatgtag tttggtgggg gtgaatgaat
     1381 gaatggtgtt catgacaaaa aaaaaaa
//