From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: M.musculus Thy-1 mRNA for Thy-1 antigen (unmethylated island &
Date: 25 Jul 92 10:05:18 GMT
Distribution: bionet
Checksum: 23585     4

LOCUS       MUSTHY1PR    1339 bp ds-DNA             ROD       25-JUL-1992
DEFINITION  M.musculus Thy-1 mRNA for Thy-1 antigen (unmethylated island &
            promoter elements)
ACCESSION   X17683
KEYWORDS    CpG-rich region; GPI-linked glycoprotein; T-cell marker;
            Thy-1 antigen; adhesion molecule; immunoglobulin superfamily;
            neuronal antigen; unmethylated island.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1339)
  AUTHORS   Gundersen,G., Kolsto,A.-B., Larsen,F. and Prydz,H.
  TITLE     tissue-specific methylation of a CpG island in transgenic mice
  JOURNAL   Gene 113, 207-214 (1992)
  STANDARD  full automatic
COMMENT     *source: strain=AKR; *source: haplotype=Thy-1.1 allele; *source:
            clone_library=lambda 641; AKR-DNA/EcoRI; *source: clone=9kb M.H
            Thy-1 hybrid gene/pUC8; *source: chromosome=9;
            See also X02772, M12380 & Ingraham H.A., Mol. Cell Biol. 6:
            2923-2931(1986)
            From EMBL    entry MMTHY1PR;  dated 21-MAY-1992.
FEATURES             Location/Qualifiers
     mRNA            join(393..445,690..831)
                     /gene="Thy-1"
     misc_feature    1..1339
                     /note="methylation-free island"
     misc_binding    276..283
                     /bound_moiety="SRE-1.1"
     misc_binding    312..317
                     /bound_moiety="NF1"
     promoter        332..340
                     /note="nonameric promoter"
     exon            392..445
                     /number=1
                     /note="1a"
     repeat_region   560..569
                     /note="decameric"
     promoter        636..644
                     /note="nonameric promoter"
     exon            690..831
                     /number=1
                     /note="1b"
     repeat_region   859..868
                     /note="decameric"
     repeat_region   905..914
                     /note="decameric"
     repeat_region   917..926
                     /note="decameric"
BASE COUNT      304 a    373 c    425 g    237 t
ORIGIN
        1 gatctccagc caagaggcaa aggaatgggg gaagctggag ggcctccctc tggtttatcc
       61 aggcttctga aggttctagc aaagaaaggg ttacaacctt aaaaggagag cgtcccgggg
      121 tatgggtaga agactgctcc accccgaccc ccagggtccc taaccgtctt ttccttgggc
      181 gagtcagccc aatcacagga ctgagagtgc ctctttagta gcagcaagcc acttcggaca
      241 cccaaatgga acacctccag tcagccctcg ccgaccaccc caccccctcc atccttttcc
      301 ctccgcctcc gattggctga atctagagtc cctccctgct cccccccccc ctctccccac
      361 cccaggtgaa aactgcgggc ttcagcgctg ggtgcagcaa ctggaggcgt tggcgcacca
      421 ggaggaggct gcagctaggg gagtccaggt gagagcaggc cggcgggagg gacccgcaca
      481 tgcaaggaca gccgcagggc gaggatgcaa gccttcccca gctacagttt tgggaaagga
      541 taccaggcgc tcctatacgg gggcgcggga actggggaaa gaaggtgctc ccaggacgag
      601 gtgggagagg aaggcagtgc ggggtcccgg gctttctccc tgctaagcca cgctttcaag
      661 atggggtgcc ggaagagaac cgtgaggaag gacatcaagg acagcctttg gtccccaagc
      721 tcagatcgct ttagtggtgc gaatagaggg aggaggtggg tggcaaactg gagggagtcc
      781 ccgccgggtg acctcgtggc tggctgggtg cggggcacgc aggtaagaaa accgcaatgt
      841 tgcgggaggg gactgggtgg ggcgcggggg agggaaagct agaaaggatg cgagggagcg
      901 gaggggggag cggggagggg agcgggagaa tctcaactgg tagaggaaga ttaaaatgag
      961 gaaatagcat cagggtgggt tagccaagcc gggcctcagg gaaagggcgc aaagtttgtc
     1021 tgggagtggg cttaggtggg ctggtaatga gattcgaggc gccgaaaaca ctcgtgcgcc
     1081 tctgccaaat cacggtaccc ctgtatctag ttctgccagg cttctccagc cccagcccca
     1141 gccccaattc ttttctctag tgttccccct tccctcccct gaatctcaag cccacactcc
     1201 ctcctccata acccactgtt atcaaatcca agtcctttgg cacccaacaa ccatcaggag
     1261 gcggaagcag acgggtggag tttgagatca acttgggcta catcaagttc caagctcacc
     1321 aaggcttctt taggagatc
//