From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human mRNA for platelet-derived growth factor PDGF-A.
Date: 29 Sep 92 10:06:47 GMT
Distribution: bionet
Checksum: 04178     5

LOCUS       HUMPDGFA     2305 bp ss-mRNA            PRI       29-SEP-1992
DEFINITION  Human mRNA for platelet-derived growth factor PDGF-A.
ACCESSION   X06374
KEYWORDS    growth factor; platelet-derived growth factor.
SOURCE      human (Homo sapiens).
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2305)
  AUTHORS   Hoppe,J., Schumacher,L., Eichner,W. and Weich,H.A.
  TITLE     The long 3'-untranslated regions of the PDGF-A and -B mRNAs are
            only distantly related
  JOURNAL   FEBS Lett. 223, 243-246 (1987)
  STANDARD  simple automatic
COMMENT     *source: cell line=U-2OS osteosarcoma cells; clone=pPG2-F.  **map:
            chromosomal location=chromosome 7;
               EMBL features not translated to GenBank features:
               key        from     to       description
               POLYA      2305   2305       polyA site
FEATURES             Location/Qualifiers
     CDS             404..994
                     /note="PDGF-A"
                     /product="platelet-derived growth factor A chain"
                     /gene="PDGFA"
                     /codon_start=1
                     /translation="MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDL
                     QRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVI
                     YEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRK
                     KPKLKEVQVRLEEHLECACATTSLNPDYREEDTDVR"
BASE COUNT      500 a    617 c    595 g    593 t
ORIGIN
        1 ttcttggggc tgatgtccgc aaatatgcag aattaccggc cgggtcgctc ctgaagccag
       61 cgcggggagc gagcgcggcg gcggccagca ccgggaacgc accgaggaag aagcccagcc
      121 cccgccctcc gccccttccg tccccacccc ctacccggcg gcccaggagg ctccccggct
      181 gcggcgcgca ctccctgttt ctcctcctcc tggctggcgc tgcctgcctc tccgcactca
      241 ctgctcgccg ggcgccgtcc gccagctccg tgctccccgc gccaccctcc tccgggccgc
      301 gctccctaag ggatggtact gaatttcgcc gccacaggag accggctgga gcgcccgccc
      361 cgcgcctcgc ctctcctccg agcagccagc gcctcgggac gcgatgagga ccttggcttg
      421 cctgctgctc ctcggctgcg gatacctcgc ccatgttctg gccgaggaag ccgagatccc
      481 ccgcgaggtg atcgagaggc tggcccgcag tcagatccac agcatccggg acctccagcg
      541 actcctggag atagactccg tagggagtga ggattctttg gacaccagcc tgagagctca
      601 cggggtccac gccactaagc atgtgcccga gaagcggccc ctgcccattc ggaggaagag
      661 aagcatcgag gaagctgtcc ccgctgtctg caagaccagg acggtcattt acgagattcc
      721 tcggagtcag gtcgacccca cgtccgccaa cttcctgatc tggcccccgt gcgtggaggt
      781 gaaacgctgc accggctgct gcaacacgag cagtgtcaag tgccagccct cccgcgtcca
      841 ccaccgcagc gtcaaggtgg ccaaggtgga atacgtcagg aagaagccaa aattaaaaga
      901 agtccaggtg aggttagagg agcatttgga gtgcgcctgc gcgaccacaa gcctgaatcc
      961 ggattatcgg gaagaggaca cggatgtgag gtgaggatga gccgcagccc tttcctggga
     1021 catggatgta catggcgtgt tacattcctg aacctactat gtacggtgct ttattgccag
     1081 tgtgcggtct ttgttctcct ccgtgaaaaa ctgtgtccga gaacactcgg gagaacaaag
     1141 agacagtgca catttgttta atgtgacatc aaagcaagta ttgtagcact cggtgaagca
     1201 gtaagaagct tccttgtcaa aaagagagag agagagagag agagagaaaa caaaaccaca
     1261 aatgacaaaa acaaaacgga ctcacaaaaa tatctaaact cgatgagatg gagggtcgcc
     1321 ccgtgggatg gaagtgcaga ggtctcagca gactggattt ctgtccgggt ggtcacaggt
     1381 gcttttttgc cgaggatgca gagcctgctt tgggaacgac tccagagggg tgctggtggg
     1441 ctctgcaggg cccgcaggaa gcaggaatgt cttggaaacc gccacgcgaa ctttagaaac
     1501 cacacctcct cgctgtagta tttaagccca tacagaaacc ttcctgagag ccttaagtgg
     1561 tttttttttt tgtttttgtt ttgttttttt tttttttgtt tttttttttt tttttttttt
     1621 ttacaccata aagtgattat taagcttcct tttactcttt ggctagcttt tttttttttt
     1681 tttttttttt ttttttttaa ttatctcttg gatgacattt acaccgataa cacacaggct
     1741 gctgtaactg tcaggacagt gcgacggtat ttttcctagc aagatgcaaa ctaatgagat
     1801 gtattaaaat aaacatggta tacctaccta tgcatcattt cctaaatgtt tctggctttg
     1861 tgtttctccc ttaccctgct ttatttgtta atttaagcca ttttgaaaga actatgcgtc
     1921 aaccaatcgt acgccgtccc tgcggcacct gccccagagc ccgtttgtgg ctgagtgaca
     1981 acttgttccc cgcagtgcac acctagaatg ctgtgttccc acgcggcacg tgagatgcat
     2041 tgccgcttct gtctgtgttg ttggtgtgcc ctggtgccgt ggtggcggtc actccctctg
     2101 ctgccagtgt ttggacagaa cccaaattct ttatttttgg taagatattg tgctttacct
     2161 gtattaacag aaatgtgtgt gtgtggtttg tttttttgta aaggtgaagt ttgtatgttt
     2221 acctaatatt acctgttttg tatacctgag agcctgctat gttcttcttt tgttgatcca
     2281 aaattaaaaa aaaaatacca ccaac
//