From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Drosophila melanogaster hu-li tai shao (hts) mRNA, complete cds.
Date: 6 Nov 92 18:27:38 GMT
Distribution: bionet
Checksum: 62177 9

LOCUS       DROHTSC      3922 bp ss-mRNA            INV       02-NOV-1992
DEFINITION  Drosophila melanogaster hu-li tai shao (hts) mRNA, complete cds.
ACCESSION   L05016
KEYWORDS    adducin; homologue; hu-li tai shao protein;
            membrane skeletal protein.
SOURCE      Drosophila melanogaster (library: Spradlin's) female ovary cDNA to
            mRNA.
  ORGANISM  Drosophila melanogaster
            Eukaryota; Animalia; Metazoa; Arthropoda; Uniramia; Insecta;
            Pterygota; Neoptera; Holometabola; Diptera; Brachycera;
            Cyclorrhapha; Schizophora; Drosophiloidea; Drosophilidae.
REFERENCE   1  (bases 1 to 3922)
  AUTHORS   Yue,L. and Spradling,A.C.
  TITLE     hu-li tai shao, a gene required for ring canal formation during
            Drosophila oogenesis, encodes a homolog of adducin
  JOURNAL   Genes Dev. (1993) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     exon            1..186
                     /number=1
                     /gene="hts"
     exon            187..235
                     /number=2
                     /gene="hts"
     exon            236..831
                     /number=3
                     /gene="hts"
     exon            832..1543
                     /number=4
                     /gene="hts"
     exon            1544..1667
                     /number=5
                     /gene="hts"
     exon            1668..1778
                     /number=6
                     /gene="hts"
     exon            1779..2073
                     /number=7
                     /gene="hts"
     exon            2074..2154
                     /number=8
                     /gene="hts"
     exon            2155..2226
                     /number=9
                     /gene="hts"
     exon            2227..3922
                     /number=10
                     /gene="hts"
     CDS             252..3722
                     /function="required for assembling actin at ring canals in
                     developing egg chambers"
                     /note="homolog of mammalian membrane skeletal protein
                     adducin"
                     /note="there are multiple transcripts for the hts gene;
                     the cDNA sequence submitted here corresponds to the 4.5 Kb
                     ovarian transpcript"
                     /citation=[1]
                     /gene="hts"
                     /product="hu-li tai shao protein"
                     /codon_start=1
                     /translation="MTEVEQPPQNGIDPTAGEDDDNSKARPADIEQDMREMERRKRVE
                     AIMGSKLFREELERIVDSARDGGAGASGILQQLSDIVGVPVSRVGSVFKSSNCMVPIN
                     DIRGVESMGYAKGEKILRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYG
                     LLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSP
                     VVAISSLKTGLLPLTKDACVLGEITTHAYTGLFDEEERNRLVRSLGPNSKVILLTNHG
                     ALCCGETIEEAFFAACHIVQACETQLKLLPVGLDNLVLIPEESRKAIYEQSRRPPEDL
                     EKKFAAVAAAEDGAATVEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDNAGYRTGYI
                     YRHPLIKSDPPKPKNDVELPPAVSSLGYLLEEEELFRQGIWKKGDIRKGGDRSRWLNS
                     PNVYQKVEVLETGTPDPKKITKWVAEGSPTHSTPVRIEDPLQFVPAGTNPREFKRVQQ
                     LIKDNRRADKISAGPQSHILEGVTWDEASRLKDATVSQAGDHVVMMGAASKGIIQRGF
                     QHNATVYKAPYAKNPFDNVTDDELNEYKRTVERKKKSVHGEYTDTDFSESEAVLQAGT
                     KKYPQSEPETEHQVIEIQTQQAPVPRQAEVVLSDALVSQLAQKYAFLYSPGQYMYGCL
                     KMAPLMQKVYVIHKVEPVSKHNYPPVNDGNMSIHHNESGAGFLAHESSVISSTPVRNA
                     LASVSFPEERNHSILGLSSTPYRTISHFGFNCPLITSPTILLHPEHRSIWQRVAEQRE
                     KVVSFIDLTTLSLDNRKLLNVVTSTHPTQCQSQSQSFISEKHIQLEVTPPKRKQRVYS
                     ATISSGLDDSLDELDSLMSGLAINMPRSREQDSGLYRSYTFLPSNHALPKDTDANDRD
                     QTDRERPEAEQEESFHCAGDSGIGDSTGRRPRLATTSNDSSIQEAEAYTQGKHVKLTL
                     SSSPTPTATQSPATIEILINVSLRNAECVQTVQTHEQEFRAKLERVIDEEIHYISQQL
                     AFKQRQAELHEQQTTSRAPIATPSFTTMHPPAPASSSSMVHRSNSAPELCHTYSYVAV
                     GDLSTKQDQASPQLPAEGEPLNDILSSLEKELERLLNSVVTAHMLHNKAIIHECRARF
                     SQLADGIVSS"
BASE COUNT     1025 a   1020 c   1022 g    855 t
ORIGIN      
        1 gtgtgtttgt acgaattagc ggctgaaaac caaaaaccga ggtgcgagag cgagaatacg
       61 tttataaaaa acgcgtgcgt ttctcctcta acacatacag tgagtgtgac cgttgtattt
      121 gtgacctgtg cctgtgttag cggccactgg aggatcaacg aatttaaaag aatactaaaa
      181 gtaccgggac atcaatataa aagtattata accacgcaac aaattcaatt ttaagcattt
      241 taactgaaat catgactgaa gttgagcaac cgccacagaa tggcatagat cccactgccg
      301 gcgaagatga tgacaatagc aaagcacgtc ccgcggatat tgaacaggat atgcgcgaaa
      361 tggagcgtcg caagcgagtc gaggctataa tgggctcgaa actgttccgc gaggagctgg
      421 agcgtatcgt ggactcggcg cgcgatggag gtgctggcgc tagtggaatc ctgcagcagc
      481 tgtcggacat tgtgggcgta ccagtgtcca gggtgggcag cgtcttcaag agcagcaact
      541 gcatggtgcc aatcaacgat atacgcggcg tcgagtccat gggctatgcc aagggcgaga
      601 agatactccg gtgcaagctg gccgccacat tccgtctgct cgatctgtac ggctggaccc
      661 agggtctggg ggcacagatc accgcccgac tcaaggtcga tcaggagtac ttcctggtta
      721 acccatacgg cctgctttac cacgagatca ctgcctcagc gctgaacaag gtggatatgc
      781 aaggacagat tgtggagcag ggcaccacca actttggcgg caacaagagt cactttgtcc
      841 tccattcggt ggtacatgct gcccgtccag atattcgatg cgccatctat atcggctgca
      901 gtccagtcgt ggctatttcc tcactgaaga ctggtctatt gccgttgacc aaggatgcct
      961 gtgtgctggg cgagatcacc actcacgctt atactggtct attcgacgag gaggagcgca
     1021 atcgattggt ccgcagcctt ggtcccaact ccaaggtgat tctgttaact aatcacggtg
     1081 ctttgtgctg cggagagacc atcgaggaag ccttcttcgc cgcctgtcac attgtacagg
     1141 cgtgtgagac gcaactgaag ctgttgcccg tcggtttgga taacttggtg ctgattccag
     1201 aggagtcgcg caaggccatt tacgagcagt cgcgccggcc gccggaggat ctggagaaga
     1261 agtttgccgc cgtcgccgct gccgaagatg gtgctgctac tgttgaaaag gatgcagccg
     1321 aagcagtacc caaggttggc agtccgccca agtggcgtgt gggtggtgct gaatttgagg
     1381 ccttgatgcg catgctggac aatgctggct atcgcactgg ctatatctac cgccatccac
     1441 tgatcaaatc ggatcctccc aagcctaaga acgatgtcga actaccgcca gctgtttcat
     1501 cactgggcta tcttcttgag gaggaggaac tcttccgtca agggatctgg aagaagggag
     1561 atattcgcaa aggcggcgac cgcagtcggt ggctcaactc gccaaacgtt taccaaaagg
     1621 tcgaggttct ggagaccggc actccggatc ccaagaagat tacaaagtgg gtggctgagg
     1681 gttcccccac ccactcaacg ccagtgagga tagaagatcc actccagttt gtgcctgcag
     1741 gaaccaatcc aagggaattt aagcgtgtcc agcaactaat taaggacaac cgccgggcag
     1801 ataagatttc agccggacca cagtcgcata ttctggaggg cgtgacatgg gacgaggcga
     1861 gccgactcaa ggatgcaacg gtctcgcagg ccggcgatca tgtcgtcatg atgggtgccg
     1921 cctccaaggg aatcattcag cgtggcttcc agcacaatgc cactgtctac aaggcaccgt
     1981 atgctaagaa cccattcgat aacgtcacag acgatgaact caatgaatac aaacgcacgg
     2041 tggagcgcaa aaagaaatcg gtgcatggcg aatataccga cacagacttt tcggaatccg
     2101 aagcggtcct gcaggcgggg acaaagaaat acccacaaag cgaacccgag accgagcacc
     2161 aggtcattga gatccaaaca cagcaagcgc cagtgccaag gcaggcggaa gtcgtgctga
     2221 gcgatgcact tgtctctcaa ctggctcaaa agtatgcgtt cctttattcg cctggccaat
     2281 acatgtatgg ctgcctgaaa atggctccat taatgcagaa ggtttatgtt atacacaagg
     2341 tcgagcccgt cagcaagcac aactatccgc cagttaacga tggcaatatg agtattcatc
     2401 acaacgaaag tggagccgga ttcctggccc atgagtccag cgttattagt agcacccccg
     2461 tacgcaatgc cttggcatca gtatcatttc cggaagagag gaatcattct attttgggct
     2521 tatcatcaac tccgtatcgc accatctcgc atttcgggtt caattgtccg cttattacgt
     2581 caccaaccat tctcctgcat cccgaacatc gatccatttg gcaacgggtg gccgagcagc
     2641 gcgagaaggt tgtgtccttc atagatctca caacattgag cttggacaac cgcaagctgc
     2701 tcaatgtagt gacatcaacg catccaaccc agtgccaatc gcaatcgcaa tcctttatct
     2761 ctgagaagca cattcagctg gaagttacgc caccgaagcg aaagcagcgt gtctacagcg
     2821 ccaccatcag cagtggtcta gacgacagcc tcgatgagct ggactccctg atgagcggcc
     2881 tagccatcaa tatgccgcgc agtcgggagc aggacagcgg tctgtaccgc agctacacct
     2941 ttctacccag taatcatgct ctgcccaagg atacagatgc caatgatagg gatcaaacgg
     3001 atcgtgagcg accagaagcg gagcaggagg aaagttttca ctgcgcaggc gacagtggta
     3061 ttggcgattc caccggccgg cgtccgcgtc tggccaccac cagcaatgat tcgtcgattc
     3121 aagaggccga agcctacacc cagggcaagc acgtcaagtt gaccttgagc agctcaccca
     3181 cgccgacggc cacacagtca cctgcaacca tcgaaattct tatcaacgta tcgctgcgca
     3241 atgccgagtg cgtccaaacg gtccagaccc atgagcagga gtttcgcgcc aagttggagc
     3301 gagtaatcga cgaggagatc cactatattt cgcagcaact cgcatttaaa cagcgacagg
     3361 cagagttgca tgaacaacag actacatcgc gggctccaat cgctacgcct tctttcacaa
     3421 ctatgcatcc gccggcaccg gcttcttcat catccatggt tcaccgcagc aactcggcac
     3481 cagaactgtg ccacacctat agctatgtgg ccgtgggcga tttgtcgacc aaacaggatc
     3541 aagcctctcc acaactgcca gcggagggtg agccgttgaa tgatatactc agtagtttgg
     3601 agaaggaact ggagcgtctg ctgaacagcg tggtgacagc ccacatgctg cacaacaagg
     3661 ccatcataca cgagtgccgg gctcgcttct cgcagctggc cgatggaatt gtcagctcgt
     3721 agatacatat tatgattttg atggaaaatt tacatcttcg cttttgttgt gatatttgaa
     3781 aatcgacaac agtgaaatga ttgtataaag caactagatt aagtttaatg atgataattt
     3841 ggaaatcttc aaatcgaact aatgcatttt tttacttctt tgttctctta atttaaatgt
     3901 taagactgta acttaagtac aa
//