From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Pig MHC class II (SLA-DR-alpha) mRNA, complete cds.
Date: 29 Dec 92 21:38:49 GMT
Distribution: bionet
Checksum: 39964 4

LOCUS       PIGMHCIIDD   1256 bp ss-mRNA            MAM       15-DEC-1992
DEFINITION  Pig MHC class II (SLA-DR-alpha) mRNA, complete cds.
ACCESSION   M93028
KEYWORDS    cell surface glycoprotein; class II gene;
            immunoglobulin heavy chain; integral membrane protein;
            major histocompatibility complex.
SOURCE      Sus scrofa (strain Minnesota miniature swine, sub_species
            domesticus) (library: lambda gt10 (SCAd)) adult spleen and blood
            cDNA to mRNA.
  ORGANISM  Sus scrofa
            Eukaryota; Animalia; Chorqata; Vertebrata; Mammalia; Theria;
            Eutheria; Artiodactyla; Suiformes; Suidae.
REFERENCE   1  (bases 1 to 1256)
  AUTHORS   Hirsch,F., Germana,S., Gustafsson,K., Pratt,K., Sachs,D.H. and
            Leguern,C.
  TITLE     Structure and expression of class II alpha genes in miniature swine
  JOURNAL   J. Immunol. 149, 841-846 (1992)
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     sig_peptide     78..143
                     /gene="SLA-DR-alpha"
                     /codon_start=1
     mat_peptide     144..833
                     /product="MHC class II DR-alpha"
                     /gene="SLA-DR-alpha"
                     /codon_start=1
     CDS             78..836
                     /gene="SLA-DR-alpha"
                     /product="MHC class II DR-alpha"
                     /codon_start=1
                     /translation="MTILGVPVLGFVITILNLQKSWAIVENHVIIQAEFYLSPDKSGE
                     FMFDFDGDEIFHVDMEKRETVWRLEEFGHFASFEAQGALANIAVDKANLEILIKRSNN
                     TPNTNVPPEVTVLSDKPVELGEPNILICFIDKFSPPVVNVTWLRNGSPVTRGVSETVF
                     LPREDHLFRKFHYLPFMPSTEDVYDCQVEHWGLDKPLLKHWEFEAQTPLPETTENTVC
                     ALGLIVALVGIIVGTVLIIKGVRKGNATERRGPL"
BASE COUNT      296 a    332 c    281 g    347 t
ORIGIN      
        1 attctctttg cttgtattgc tgtccatcct gacccaccat agctctaccg accctcatcg
       61 aggcatctaa ggagaaaatg accatacttg gggtcccagt cctgggattt gtcatcacca
      121 tcttgaacct tcagaaatca tgggctatcg tagagaatca cgtgatcatc caggctgagt
      181 tctatctgag ccctgacaaa tctggcgagt ttatgtttga ctttgacggt gatgagattt
      241 tccacgtgga tatggaaaag agggagacgg tctggcgact tgaagaattt ggacattttg
      301 ccagctttga ggctcagggt gcactggcca acatagctgt ggacaaagcc aacctggaaa
      361 tcctgatcaa gcgctccaac aacaccccga acaccaatgt acctccagaa gtgactgtgc
      421 tctcagacaa gcctgttgaa ctgggagagc ccaacatcct catctgtttc atcgacaagt
      481 tctccccgcc agtggtcaat gtcacctggc ttcgaaatgg ctcccctgtc accagaggag
      541 tgtcagagac agtcttcctg ccccgggagg accacctttt ccgcaagttc cactatctcc
      601 ccttcatgcc ctcaaccgag gatgtctatg actgccaggt ggagcactgg ggtttggaca
      661 agcctcttct caagcactgg gagtttgaag ctcaaacccc cctcccagag actacagaga
      721 acaccgtgtg tgctctgggc ctgattgtgg ctctggtggg catcatcgtc gggaccgtcc
      781 tcatcatcaa gggtgtgcgc aaaggcaacg ccactgaacg ccgagggcct ctgtgaggtg
      841 cttgcaggga atggactttg ttaaagatca atgaagatat ttcctcttga acagctttac
      901 aaacccagcg atactccagc tgttcacctc cgtgaagaca actctccttc agcactttcc
      961 agccctgaag ccactctaag tgttgatgcc ttctttaatc ttcaaattct aacatctggt
     1021 tattccctgt ttgttacccc ttcttgtgct ggctttccct ccatttccac agccttttta
     1081 ttatcaccgt gtaatgcctt tggaagagat cccatgggat cctttctctg ctatgaaacc
     1141 ttttgaatgt tctatggagg catctactgt atacttatta cttggagttt cttccaactg
     1201 tgattgtgat ttttctgaat acaataaact ttgagtgggc cttaggtgga aaaaaa
//