From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Plasmodium falciparum erythrocyte binding protein gene, complete
Date: 22 Jul 92 10:03:25 GMT
Distribution: bionet
Checksum: 00712    11

LOCUS       PFAERBPB     5057 bp ds-DNA             INV       22-JUL-1992
DEFINITION  Plasmodium falciparum erythrocyte binding protein gene, complete
            cds.
ACCESSION   M93397
KEYWORDS    erythrocyte binding protein.
SOURCE      Plasmodium falciparum DNA.
  ORGANISM  Plasmodium falciparum
            Eukaryota; Animalia; Protozoa; Microspora; Microsporea;
            Microsporida; Haemosporina; Plasmodiidae.
REFERENCE   1  (bases 1 to 5057)
  AUTHORS   Miller,L.H., Kaslow,D.C., Fang,X., Dolan,S.A., Sim,B.K. and
            Adams,J.H.
  TITLE     A family of erythrocyte binding proteins of malaria parasites
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. (1992) In press
  STANDARD  full automatic
FEATURES             Location/Qualifiers
     CDS             join(56..4238,4364..4442,4550..4632,4773..4855)
                     /product="erythrocyte binding protein"
                     /gene="erythrocyte binding protein"
                     /codon_start=1
                     /translation="MKCNISIYFFASFFVLYFAKARNEYDIKENEKFLDVYKEKFNEL
                     DKKKYGNVQKTDKKIFTFIENKLDILNNSKFNKRWKSYGTPDNIDKNMSLINKHNNEE
                     MFNNNYQSFLSTSSLIKQNKYVPINAVRVSRILSFLDSRINNGRNTSSNNEVLSNCRE
                     KRKGMKWDCKKKNDRSNYVCIPDRRIQLCIVNLSIIKTYTKETMKDHFIEASKKESQL
                     LLKKNDNKYNSKFCNDLKNSFLDYGHLAMGNDMDFGGYSTKAENKIQEVFKGAHGEIS
                     EHKIKNFRKEWWNEFREKLWEAMLSEHKNNINNCKNIPQEELQITQWIKEWHGEFLLE
                     RDNRSKLPKSKCKNNTLYEACEKECIDPCMKYRDWIIRSKFEWHTLSKEYETQKVPKE
                     NAENYLIKISENKNDAKVSLLLNNCDAEYSKYCDCKHTTTLVKSVLNGNDNTIKEKRE
                     HIDLDDFSKFGCDKNSVDTNTKVWECKNPYILSTKDVCVPPRRQELCLGNIDRIYDKN
                     LLMIKEHILAIAIYESRILKRKYKNKDDKEVCKIINKTFADIRDIIGGTDYWNDLSNR
                     KLVGKINTNSKYVHRNKKNDKLFRDEWWKVIKKDVWNVISWVFKDKTVCKEDDIENIP
                     QFFRWFSEWGDDYCQDKTKMIETLKVECKEKPCEDDNCKSKCNSYKEWISKKKEEYNK
                     QAKQYQEYQKGNNYKMYSEFKSIKPEVYLKKYSEKCSNLNFEDEFKEELHSDYKNKCT
                     MCPEVKDVPISIIRNNEQTSQEAVPEENTEIAHRTETPSISEGPKGNEQKERDDDSLS
                     KISVSPENSRPETDAKDTSNLLKLKGDVDISMPKAVIGSSPNDNINVTEQGDNISGVN
                     SKPLSDDVRPDKKELEDQNSDESEETVVNHISKSPSINNGDDSGSGSATVSESSSSNT
                     GLSIDDDRNGDTFVRTQDTANTEDVIRKENADKDEDEKGADEERHSTSESLSSPEEKM
                     LTDNEGGNSLNHEEVKEHTSNSDNVQQSGGIVNMNVEKELKDTLENPSSSLDEGKAHE
                     ELSEPNLSSDQDMSNTPGPLDNTSEETTERISNNEYKVNEREDERTLTKEYEDIVLKS
                     HMNRESDDGELYDENSDLSTVNDESEDAEAKMKGNDTSEMSHNSSQHIESDQQKNDMK
                     TVGDLGTTHVQNEISVPVTGEIDEKLRESKESKIHKAEEERLSHTDIHKINPEDRNSN
                     TLHLKDIRNEENERHLTNQNINISQERDLQKHGFHTMNNLHGDGVSERSQINHSHHGN
                     RQDRGGNSGNVLNMRSNNNNFNNIPSRYNLYDKKLDLDLYENRNDSTTKELIKKLAEI
                     NKCENEISVKYCDHMIHEEIPLKTCTKEKTRNLCCAVSDYCMSYFTYDSEEYYNCTKR
                     EFDDPSYTCFRKEAFSSMPYYAGAGVLFIILVILGASQAKYQSSEGVMNENNENNFLF
                     EVTDNLDKLSNMFNQQVQETNINDFSEYHEDINDIKFKI"
     exon            56..4238
                     /number=1
                     /gene="erythrocyte binding protein"
     intron          4239..4363
                     /number=1
                     /gene="erythrocyte binding protein"
     exon            4364..4442
                     /number=2
                     /gene="erythrocyte binding protein"
     intron          4443..4549
                     /number=2
                     /gene="erythrocyte binding protein"
     exon            4550..4632
                     /number=3
                     /gene="erythrocyte binding protein"
     intron          4633..4772
                     /number=3
                     /gene="erythrocyte binding protein"
     exon            4773..4855
                     /number=4
                     /gene="erythrocyte binding protein"
BASE COUNT     2192 a    483 c    845 g   1537 t
ORIGIN
        1 tatatatata tatatatata gataataaca tataaatata ttcaatgtgc atacaatgaa
       61 atgtaatatt agtatatatt tttttgcttc cttctttgtg ttatattttg caaaagctag
      121 gaatgaatat gatataaaag agaatgaaaa atttttagac gtgtataaag aaaaatttaa
      181 tgaattagat aaaaagaaat atggaaatgt tcaaaaaact gataagaaaa tatttacttt
      241 tatagaaaat aaattagata ttttaaataa ttcaaaattt aataaaagat ggaagagtta
      301 tggaactcca gataatatag ataaaaatat gtctttaata aataaacata ataatgaaga
      361 aatgtttaac aacaattatc aatcattttt atcgacaagt tcattaataa agcaaaataa
      421 atatgttcct attaacgctg tacgtgtgtc taggatatta agtttcctgg attctagaat
      481 taataatgga agaaatactt catctaataa cgaagtttta agtaattgta gggaaaaaag
      541 gaaaggaatg aaatgggatt gtaaaaagaa aaatgataga agcaactatg tatgtattcc
      601 tgatcgtaga atccaattat gcattgttaa tcttagcatt attaaaacat atacaaaaga
      661 gaccatgaag gatcatttca ttgaagcctc taaaaaagaa tctcaacttt tgcttaaaaa
      721 aaatgataac aaatataatt ctaaattttg taatgatttg aagaatagtt ttttagatta
      781 tggacatctt gctatgggaa atgatatgga ttttggaggt tattcaacta aggcagaaaa
      841 caaaattcaa gaagttttta aaggggctca tggggaaata agtgaacata aaattaaaaa
      901 ttttagaaaa gaatggtgga atgaatttag agagaaactt tgggaagcta tgttatctga
      961 gcataaaaat aatataaata attgtaaaaa tattccccaa gaagaattac aaattactca
     1021 atggataaaa gaatggcatg gagaattttt gcttgaaaga gataatagat caaaattgcc
     1081 aaaaagtaaa tgtaaaaata atacattata tgaagcatgt gagaaggaat gtattgatcc
     1141 atgtatgaaa tatagagatt ggattattag aagtaaattt gaatggcata cgttatcgaa
     1201 agaatatgaa actcaaaaag ttccaaagga aaatgcggaa aattatttaa tcaaaatttc
     1261 agaaaacaag aatgatgcta aagtaagttt attattgaat aattgtgatg ctgaatattc
     1321 aaaatattgt gattgtaaac atactactac tctcgttaaa agcgttttaa atggtaacga
     1381 caatacaatt aaggaaaagc gtgaacatat tgatttagat gatttttcta aatttggatg
     1441 tgataaaaat tccgttgata caaacacaaa ggtgtgggaa tgtaaaaacc cttatatatt
     1501 atccactaaa gatgtatgtg tacctccgag gaggcaagaa ttatgtcttg gaaacattga
     1561 tagaatatac gataaaaacc tattaatgat aaaagagcat attcttgcta ttgcaatata
     1621 tgaatcaaga atattgaaac gaaaatataa gaataaagat gataaagaag tttgtaaaat
     1681 cataaataaa actttcgctg atataagaga tattatagga ggtactgatt attggaatga
     1741 tttgagcaat agaaaattag taggaaaaat taacacaaat tcaaaatatg ttcacaggaa
     1801 taaaaaaaat gataagcttt ttcgtgatga gtggtggaaa gttattaaaa aagatgtatg
     1861 gaatgtgata tcatgggtat tcaaggataa aactgtttgt aaagaagatg atattgaaaa
     1921 tataccacaa ttcttcagat ggtttagtga atggggtgat gattattgcc aggataaaac
     1981 aaaaatgata gagactctga aggttgaatg caaagaaaaa ccttgtgaag atgacaattg
     2041 taaaagtaaa tgtaattcat ataaagaatg gatatcaaaa aaaaaagaag agtataataa
     2101 acaagccaaa caataccaag aatatcaaaa aggaaataat tacaaaatgt attctgaatt
     2161 taaatctata aaaccagaag tttatttaaa gaaatactcg gaaaaatgtt ctaacctaaa
     2221 tttcgaagat gaatttaagg aagaattaca ttcagattat aaaaataaat gtacgatgtg
     2281 tccagaagta aaggatgtac caatttctat aataagaaat aatgaacaaa cttcgcaaga
     2341 agcagttcct gaggaaaaca ctgaaatagc acacagaacg gaaactccat ctatctctga
     2401 aggaccaaaa ggaaatgaac aaaaagaacg tgatgacgat agtttgagta aaataagtgt
     2461 atcaccagaa aattcaagac ctgaaactga tgctaaagat acttctaact tgttaaaatt
     2521 aaaaggagat gttgatatta gtatgcctaa agcagttatt gggagcagtc ctaatgataa
     2581 tataaatgtt actgaacaag gggataatat ttccggggtg aattctaaac ctttatctga
     2641 tgatgtacgt ccagataaaa aggaattaga agatcaaaat agtgatgaat cggaagaaac
     2701 tgtagtaaat catatatcaa aaagtccatc tataaataat ggagatgatt caggcagtgg
     2761 aagtgcaaca gtgagtgaat ctagtagttc aaatactgga ttgtctattg atgatgatag
     2821 aaatggtgat acatttgttc gaacacaaga tacagcaaat actgaagatg ttattagaaa
     2881 agaaaatgct gacaaggatg aagatgaaaa aggcgcagat gaagaaagac atagtacttc
     2941 tgaaagctta agttcacctg aagaaaaaat gttaactgat aatgaaggag gaaatagttt
     3001 aaatcatgaa gaggtgaaag aacatactag taattctgat aatgttcaac agtctggagg
     3061 aattgttaat atgaatgttg agaaagaact aaaagatact ttagaaaatc cttctagtag
     3121 cttggatgaa ggaaaagcac atgaagaatt atcagaacca aatctaagca gtgaccaaga
     3181 tatgtctaat acacctggac ctttggataa caccagtgaa gaaactacag aaagaattag
     3241 taataatgaa tataaagtta acgagaggga agatgagaga acgcttacta aggaatatga
     3301 agatattgtt ttgaaaagtc atatgaatag agaatcagac gatggtgaat tatatgacga
     3361 aaattcagac ttatctactg taaatgatga atcagaagac gctgaagcaa aaatgaaagg
     3421 aaatgataca tctgaaatgt cgcataatag tagtcaacat attgagagtg atcaacagaa
     3481 aaacgatatg aaaactgttg gtgatttggg aaccacacat gtacaaaacg aaattagtgt
     3541 tcctgttaca ggagaaattg atgaaaaatt aagggaaagt aaagaatcaa aaattcataa
     3601 ggctgaagag gaaagattaa gtcatacaga tatacataaa attaatcctg aagatagaaa
     3661 tagtaataca ttacatttaa aagatataag aaatgaggaa aacgaaagac acttaactaa
     3721 tcaaaacatt aatattagtc aagaaaggga tttgcaaaaa catggattcc ataccatgaa
     3781 taatctacat ggagatggag tttccgaaag aagtcaaatt aatcatagtc atcatggaaa
     3841 cagacaagat cgggggggaa attctgggaa tgttttaaat atgagatcta ataataataa
     3901 ttttaataat attccaagta gatataattt atatgataaa aaattagatt tagatcttta
     3961 tgaaaacaga aatgatagta caacaaaaga attaataaag aaattagcag aaataaataa
     4021 atgtgagaac gaaatttctg taaaatattg tgaccatatg attcatgaag aaatcccatt
     4081 aaaaacatgc actaaagaaa aaacaagaaa tctgtgttgt gcagtatcag attactgtat
     4141 gagctatttt acatatgatt cagaggaata ttataattgt acgaaaaggg aatttgatga
     4201 tccatcttat acatgtttca gaaaggaggc tttttcaagt atgatattca aatttttaat
     4261 aacaaataaa atatattatt atttttatac ttacaaaact gcaaaagtaa caataaaaaa
     4321 aattaatttc tcattaattt tttttttctt tttttctttt taggtatgcc atattatgca
     4381 ggagcaggtg tgttatttat tatattggtt attttaggtg cttcacaagc caaatatcaa
     4441 aggttagaaa aaataaataa aaataaaatt gagaagaatg taaattaaat atatatatat
     4501 atatatatat atatatatat atattgtatt atatattttt tttttatagt tctgaaggag
     4561 ttatgaatga gaataatgag aataattttt tatttgaagt tactgataat ttagataaat
     4621 tatccaatat gtgtaataca aatataaaaa aaaataataa ataaataaat aattacaagg
     4681 aaataaaaat gatatatatt attacattat gtttgtttac ttttatatta tcctataata
     4741 tttattttta ttttatgttt tttttttttc agtcaatcaa caagtacagg aaactaatat
     4801 caacgatttt tctgaatacc atgaggatat aaatgatatt aaatttaaga tatgatgtat
     4861 ttttttttag aaggattaat atattaaaat ggattatttt atttgttcag aataatagtt
     4921 atataagttt tatatttata actatttcct ataaaaataa aaattaaaag gatttttaat
     4981 attttttttg tgaatatata ttaagcattt tatgttaaaa tttgagaaaa aattcacata
     5041 aaagaaaaaa aaaaaaa
//