From: GenBank-Updates@net.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: H.sapiens mRNA for protein kinase C-Epsilon
Date: 28 Dec 92 21:29:43 GMT
Distribution: bionet
Checksum: 63463 5

LOCUS       HUMPKCE      2244 bp ss-RNA             PRI       01-DEC-1992
DEFINITION  H.sapiens mRNA for protein kinase C-Epsilon
ACCESSION   X65293
KEYWORDS    protein kinase C epsilon.
SOURCE      Homo sapiens RNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 2244)
  AUTHORS   Basta,P.V., Strickland,M.B., Holmes,W., Loomis,C.R., Ballas,L.M.
            and Burns,D.J.
  TITLE     Sequences and expression of human protein kinase C-EPSIlONS
  JOURNAL   Biochim. Biophys. Acta 1132, 154-160 (1992)
  STANDARD  full automatic
COMMENT     From EMBL    entry HSPKCE;  dated 15-OCT-1992.
FEATURES             Location/Qualifiers
     CDS             16..2229
                     /EC_number="2.7.1.37"
                     /product="protein kinase Cepsilon"
                     /codon_start=1
                     /translation="MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIAL
                     NVDDSRIGQTATKQKTNSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQF
                     EELLQNGSRHFEDWIDLEPEGRVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAV
                     RRRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIIT
                     KCAGLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVC
                     KMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPAS
                     GSSPSEEDRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGEN
                     GEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDV
                     DCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPR
                     SRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTT
                     FCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDV
                     LYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIK
                     PPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP"
BASE COUNT      558 a    611 c    620 g    455 t
ORIGIN      
        1 ctccccgccc cgaccatggt agtgttcaat ggccttctta agatcaaaat ctgcgaggcc
       61 gtgagcttga agcccacagc ctggtcgctg cgccatgcgg tgggaccccg gccgcagact
      121 ttccttctcg acccctacat tgccctcaat gtggacgact cgcgcatcgg ccaaacggcc
      181 accaagcaga agaccaacag cccggcctgg cacgacgagt tcgtcaccga tgtgtgcaac
      241 ggacgcaaga tcgagctggc tgtctttcac gatgccccca taggctacga cgacttcgtg
      301 gccaactgca ccatccagtt tgaggagctg ctgcagaacg ggagccgcca cttcgaggac
      361 tggattgatc tggagccaga aggaagagtg tatgtgatca tcgatctctc agggtcgtcg
      421 ggtgaagccc ctaaagacaa tgaagagcgt gtgttcaggg aacgcatgcg gccgaggaag
      481 cggcaggggg ccgtcaggcg cagggtccat caggtcaacg gccacaagtt catggccacc
      541 tatcttcggc agcccaccta ctgctcccat tgcagagact tcatctgggg tgtcatagga
      601 aagcagggat accagtgtca agtctgcacc tgcgtggtcc acaagcggtg ccacgagctc
      661 ataatcacaa agtgtgctgg gttaaagaag caggagaccc ccgaccaggt gggctcccag
      721 cggttcagcg tcaacatgcc ccacaagttc ggtatccaca actacaaggt ccctaccttc
      781 tgcgatcact gtgggtccct gctctgggga ctcttgcggc agggtttgca gtgtaaagtc
      841 tgcaaaatga atgttcaccg tcgatgtgag accaacgtgg ctcccaactg tggagtggat
      901 gccagaggaa tcgccaaagt actggccgac ctgggcgtta ccccagacaa aatcaccaac
      961 agcggccaga gaaggaaaaa gctcattgct ggtgccgagt ccccgcagcc tgcttctgga
     1021 agctcaccat ctgaggaaga tcgatccaag tcagcaccca cctccccttg tgaccaggaa
     1081 ataaaagaac ttgagaacaa cattcggaaa gccttgtcat ttgacaaccg aggagaggag
     1141 caccgggcag catcgtctcc tgatggccag ctgatgagcc ccggtgagaa tggcgaagtc
     1201 cggcaaggcc aggccaagcg cctgggcctg gatgagttca acttcatcaa ggtgttgggc
     1261 aaaggcagct ttggcaaggt catgttggca gaactcaagg gcaaagatga agtatatgct
     1321 gtgaaggtct taaagaagga cgtcatcctt caggatgatg acgtggactg cacaatgaca
     1381 gagaagagga ttttggctct ggcacggaaa cacccgtacc ttacccaact ctactgctgc
     1441 ttccagacca aggaccgcct ctttttcgtc atggaatatg taaatggtgg agacctcatg
     1501 tttcagattc agcgctcccg aaaattcgac gagcctcgtt cacggttcta tgctgcagag
     1561 gtcacatcgg ccctcatgtt cctccatcag catggagtca tctacaggga tttgaaactg
     1621 gacaacatcc ttctggatgc agaaggtcac tgcaagctgg ctgacttcgg gatgtgcaag
     1681 gaagggattc tgaatggtgt gacgaccacc acgttctgtg ggactcctga ctacatagct
     1741 cctgagatcc tgcaggagtt ggagtatggc ccctccgtgg actggtgggc cctgggggtg
     1801 ctgatgtacg agatgatggc tggacagcct ccctttgagg ccgacaatga ggacgaccta
     1861 tttgagtcca tcctccatga cgacgtgctg tacccagtct ggctcagcaa ggaggctgtc
     1921 agcatcttga aagctttcat gacgaagaat ccccacaagc gcctgggctg tgtggcatcg
     1981 cagaatggcg aggacgccat caagcagcac ccattcttca aagagattga ctgggtgctc
     2041 ctggagcaga agaagatcaa gccacccttc aaaccacgca ttaaaaccaa aagagacgtc
     2101 aataattttg accaagactt tacccgggaa gagccggtac tcacccttgt ggacgaagca
     2161 attgtaaagc agatcaacca ggaggaattc aaaggtttct cctactttgg tgaagacctg
     2221 atgccctgag agcccactgc agtt
//