HDTenEightyP/NetNews huggingface dataset:
From: kristoff@genbank.bio.net (David Kristofferson)
Newsgroups: bionet.announce
Subject: 2ND AND FINAL CALL FOR VOTES: bionet.biochem.carotenoids
Date: 1 Oct 92 23:41:35 GMT
Reply-To: biovote@genbank.bio.net

This is the second and final call for votes on
bionet.biochem.carotenoids.

----------------------------------------------------------------------
Proposal to establish bionet.carotenoids

Discussion leader: Pablo A. Scolnik (scolnipa@esvax.dnet.dupont.com)

Purpose: discussions regarding the chemistry, biochemistry,
photochemistry, role in photosynthesis, genetics, metabolism, and
health effects of carotenoids.  This newsgroup will also include
information exchange on pure compounds, mutants, techniques, and
recombinant DNA constructs.
------------------------------------------------------------------

Voting is open on bionet.biochem.carotenoids and will run through
24:00 hrs Pacific Time on 15 October 1992.  Please send your vote to
any of the following addresses:

Address                               Location        Network
-------                               --------        -------
biovote@daresbury.ac.uk               U.K.            JANET
biovote@genbank.bio.net               U.S.A.          Internet/BITNET
biovote@irlearn.ucd.ie                Ireland         EARN/BITNET

Your vote should contain a single line:

YES on bionet.biochem.carotenoids

if you favor creation of the newsgroup or

NO on bionet.biochem.carotenoids

if you think that the creation of this newsgroup will adversely affect
the BIOSCI system.  If you are simply not interested in participating
in this newsgroup, please don't cast a NO vote, but instead just don't
vote at all.

The newsgroup proposal must receive at least 80 YES votes to pass and
the number of YES votes must be greater than the number of NO votes by
at least 40.  Discussion of the newsgroup proposal is now closed and
we strongly discourage posting any messages in other forums about the
fact that a CALL FOR VOTES has been issued.

				Sincerely,

				Dave Kristofferson
				GenBank Manager

				kristoff@genbank.bio.net
From: anderson@CSHL.ORG (John Anderson)
Newsgroups: bionet.neuroscience
Subject: Summer School of Brain Research
Date: 29 Sep 92 17:13:40 GMT
Distribution: bionet


Xref: sparky bionet.neuroscience:428 alt.drugs:16670
From: alves@calvin.usc.edu (William Alves)
Newsgroups: bionet.neuroscience,alt.drugs
Subject: Neurotransmitter questions
Date: 6 Oct 92 01:41:56 GMT
Organization: University of Southern California, Los Angeles, CA
NNTP-Posting-Host: calvin.usc.edu

I am merely an interested amateur who as been reading a few books, but
they have left me with a few questions, and I hope that some of you will
indulge me by posting answers to a couple of them. Perhaps the answers
aren't known, but the things I have read so far have not made that clear.

First, this whole neurotransmitter business. As I see it, there are only
two possible effects a neurotransmitter can have on a neuron - it can
inhibit or excite the cell. Then doesn't it seem logical that there would
be only two types of neurotransmitters, instead of the pharmacopeia that
has been discovered? What is the difference between inhibition from one
neurotransmitter and another?

Second, the non-technical sources I have read have made a big deal out of
the chemical similarities between certain hallucinogens (LSD for example)
and certain neurotransmitters (serotonin for example). Yet is simple 
mimickry behind all of the drug's effects? If that is so, why do different
serotonin-like drugs have wildly different effects, and others have none
at all?

I hope I don't get deluged with "go to the library"-type flames. It's true
I haven't gone to med school, but I have been to the library, and that's
what has left me with these questions. Thanks very much for any help.

Bill
From: rchafetz@cephalo.neusc.bcm.tmc.edu (Ross Chafetz)
Newsgroups: bionet.neuroscience
Subject: EEG recordings
Date: 6 Oct 1992 18:47:41 GMT
Organization: Baylor College of Medicine, Houston,Tx
Distribution: world
NNTP-Posting-Host: cephalo.neusc.bcm.tmc.edu


Does anyone know of software that will read cortical spikewave
(typical of absence seizures) discharges recorded with an EEG?



:)
Ross
rchafetz@cephalo.neusc.bcm.tmc.edu
From: tsau@FRED.MED.YALE.EDU
Newsgroups: bionet.neuroscience
Subject: hottest topic
Date: 1 Oct 92 14:59:59 GMT
Distribution: bionet

Hello netters,
  What is the hottest topic on neuroscience?
  T.Y.
From: TSAU@BIOMED.MED.YALE.EDU
Newsgroups: bionet.neuroscience
Subject: apply
Date: 29 Sep 92 22:04:12 GMT
Distribution: bionet

Hello,
  Can I get the regular news about neuroscience from you? Thanks.
Yang Tsau
--------------------------------
Dr. Yang Tsau
Dept. of Physiology,
Yale Univ. Sch. of Med.
333 Cedar str.
P.O.Box 3333
New Haven, CT06510-8026
tel: 203-785-4047
email: tsau@biomed.med.yale.edu
--------------------------------
From: g5000005@nickel.laurentian.ca
Newsgroups: bionet.neuroscience
Subject: Wanted: Statistica 3.1 manual
Date: 30 Sep 92 19:11:13 GMT
Organization: Laurentian University

Hello netters!

	I am looking for a manual/book for the statistical analysis program 
called Statistica 3.1 (for DOS). I am currently using VAX/VMS SPSSx but I will
be graduating soon (what time is it now?) and have to decide between SPSS-PC+ 
and Statistica for my PC.

	If anyone has used this package I would be interested to hear your 
comments/criticisms regarding this package.

	Thanks in advance!

Norm
Newsgroups: bionet.neuroscience
From: olav-n@hsr.no (Olav Naerland)
Subject: EEG data needed
Organization: Rogaland University Centre
Date: Mon, 28 Sep 1992 10:37:31 GMT

Hey,

I'm testing a program for detection of epileptogenic sharp transients in EEG.
Please e-mail me if someone has any EEG data willing to share with me.
Thanks in advance.

Olav Naerland
email: olav-n@hsr.no
From: karabinos@exmed1.dnet.gwdg.de ("EXMED1::KARABINOS")
Newsgroups: bionet.neuroscience
Subject: sub
Date: 27 Sep 92 22:21:39 GMT
Distribution: bionet
Original-To: neur-sci@uk.ac.daresbury

sub bionet.neuroscience
From: bathurst@phoenix.Princeton.EDU (Bruce Bathurst)
Newsgroups: bionet.neuroscience
Subject: Re: working in labs reduces my brain capacity (s
Date: 4 Oct 92 03:14:25 GMT
Organization: Princeton University
Originator: news@nimaster

>I have a few small questions regarding brain health.
>
>Headaches.

My knowledge of neuroscience is nil, but I did suffer from nearly continuous
migraine, until a neuropsychiatrist prescribed MAO inhibitors.

A slight implication in this thread is that headaches are not damaging to the
brain itself, and I'm not sure people meant to state that.  Certainly migraine
and other neurological headaches affect the brain abnormally, as one can read
in Sach's book of descriptions.

Though it is claimed that there is no statistical correlation between those
who have classical migraine and those who have temporal-lobe epilepsy, the
published descriptions of the auras appear identical to me.  So whether the
migraine itself causes long-term damage seems open.

BTW, Universities refused to treat my migraines.  Physicians just consoled me
with the statment that it was only a headache.  The first thing a consultant
did was examine an MRI for "tiny strokes" caused by the headache process
itself.

Bruce
-- 
Department of Geological and Geophysical Sciences
Princeton University, Princeton, NJ 08544
bathurst@phoenix.princeton.edu bathurst@pucc.bitnet !princeton!phoenix!bathurst
Newsgroups: bionet.neuroscience,alt.drugs
From: ringo@craft.camp.clarkson.edu (Ringo)
Subject: Re: Neurotransmitter questions
Organization: Clarkson University
Date: Tue, 6 Oct 1992 14:07:59 GMT

alves@calvin.usc.edu (William Alves) writes:


>First, this whole neurotransmitter business. As I see it, there are only
>two possible effects a neurotransmitter can have on a neuron - it can
>inhibit or excite the cell. Then doesn't it seem logical that there would
>be only two types of neurotransmitters, instead of the pharmacopeia that
>has been discovered? What is the difference between inhibition from one
>neurotransmitter and another?

Some possible effects a neurotransmitter can have: Increase/Decrease = I/D.
I/D spontaneous firing rate.
I/D resting potential to bring it nearer to/further from threshold.
I/D activity of other NT's
I/D receptability of neuron to OTHER NT's (NT = Neurotransmitter)
I/D secretion of a neuromodulator, which can do any of the above.
Several more things, too. Won't bother to go into them.


>Second, the non-technical sources I have read have made a big deal out of
>the chemical similarities between certain hallucinogens (LSD for example)
>and certain neurotransmitters (serotonin for example). Yet is simple 
>mimickry behind all of the drug's effects? If that is so, why do different
>serotonin-like drugs have wildly different effects, and others have none
>at all?

A drug can mimic, block or enhance another NT. (Actually it can do lots
more, like prevent reuptake of an NT, prolonging its activity on the
PostSyn Neuron.) LSD is a similar chemical to Serotonin, and mimics its
effects. The LSD you've probably taken, though, is LSD-25. If you've
taken other lsd containing things, it very probably didn't have the
same isomer. It was another ergoline (class that LSD belongs to) which
had very similar, though not exactly the same effects as LSD-25.
So, taking from the list above, a drug can mimic, block, enhance, inhibit,
etc, ANY of the above things. 

I hope this has cleared things up for you somewhat.

--John Rescigno
Dept. of Psychology
Clarkson University
Nowhere, NY
From: SDELLAP@YALEVM.YCC.YALE.EDU (Neil McHale)
Newsgroups: bionet.genome.arabidopsis
Subject: POSTDOCTORAL POSITION IN LEAF DEVELOPMENT
Date: 5 Oct 92 20:04:02 GMT
Distribution: bionet


MOLECULAR GENETIC ANALYSIS OF LEAF DEVELOPMENT

A postdoctoral position is available starting September 1992 for
studies on genetic dissection of leaf development.  The work will
center on a bladeless mutant and two dominant ectopic blade
initiators in tobacco and Ds-enhancer trapping of leaf mutants in
Arabidopsis.  Applicants should have experience in histology and
molecular genetics.  Starting salary is $26,600/year plus benefits.

Send Curriculum vitae and names of three referenc
es to Dr. Neil A.
McHale, Dept. of Biochemistry and Genetics, The Connectucut
Agricultural Experiment Station, P.O. Box 1106, New Haven, CT
06504; telephone 203-789-6912, fax 203-789-7232 (or respond by
email c/o sdellap@yalevm.bitnet)
From: LEHLEF@CCIT.ARIZONA.EDU
Newsgroups: bionet.genome.arabidopsis
Subject: (none)
Date: 6 Oct 92 21:23:11 GMT
Distribution: bionet

Dear Networkers,              October 6, 1992

LEHLE SEEDS has received a special request to package EMS mutated
M2 Arabidopsis seeds by small groups of say 10 or less M1 parents.  

We would be willing to do this, but before we do, we would like some
feedback from the Arabidopsis community as to the most desirable
packaging arrangement.   We have the following two questions.

What is the best ratio of M2 seeds to M1 parent(s) to use for
packaging?  1:1, 5:1, ?    

What is the minimum number of  M2 seeds that should be provided
for each M1 parent? 

It would also be nice to know how much demand there is out there
for this type of packaging.  If you think this type of packaging would
be of interest to you, kindly express yourself by fax, phone, or letter.

Thanks,

Fred Lehle, Ph.D.

LEHLE SEEDS
3819 South Evans Suite#307
Tucson AZ 85714 USA
Tel. 602-889-3339
FAX 602-889-3403
From: MOURAD@SASK.USASK.CA
Newsgroups: bionet.genome.arabidopsis
Subject: (none)
Date: 1 Oct 92 20:37:00 GMT
Distribution: bionet

Subscription request:

Please add my address to your mailing list.

thank you, 

George Mourad

"Mourad@Sask.USask.CA"
From: Curator@FRODO.MGH.HARVARD.EDU (AAtDB Data Submission Address)
Newsgroups: bionet.genome.arabidopsis
Subject: AAtDB update coming soon
Date: 5 Oct 92 19:53:23 GMT
Distribution: bionet

AAtDB 1-2 coming soon. Send your updated information now.

Within a couple of weeks we expect to make available the first update
to AAtDB, the database of Arabidopsis information.  If you have
considered updating any of the information in AAtDB now is the time to
send in that information.

The mapping survey is currently under way and you should use the forms
that were sent via electronic and postal mail.

For other types of information please just send us the new or changed
info in an electronic mail message to curator@frodo.mgh.harvard.edu or
FAX to 617-726-6893. No particular form is required. Simply state the
information that you wish to submit as clearly as possible.

In particular we would like to verify that the Colleague information
is up-to-date. If you are not able to verify your information in the
AAtDB database using the Unix version or the Gopher and WAIS servers
you are invited to send a message to curator@frodo.mgh.harvard.edu.
We will check that your information is current in AAtDB. If you wish
to update your information please submit your information to the same
address. List any of the following types of information.

Colleague Class of Information in AAtDB.

   Full Name:
   Position (optional):
   Profession (optional):
   Complete postal mail address:
   Country:
   List of Electronic Mail Addresses (Bitnet, Internet and other):
   FAX number:
   Telex number:
   Brief Summary of Research Interests (optional):
   Keywords Describing Your Research Interests (optional):
   Lab group or Associated researchers (optional):


Any other information you wish to be included in AAtDB 1-2 should be
sent as soon as possible.

The AAtDB 1-2 release will come after the next release of the ACeDB
software for X-windows. We anticipate AAtDB 1-3 will follow around the
new year.  Also of interest to many of you the development of the
Macintosh version of the ACeDB software by Frank Eeckman (LLNL) is
going well and is currently in beta testing.

Mike Cherry
Sam Cartinhour

AAtDB is funded by the U. S. Department of Agriculture Plant Genome
Research Program through the National Agricultural Library and is
maintained by a group at the Massachusetts General Hospital and
Harvard Medical School.
From: Quail@mendel.berkeley.edu ( Peter Quail)
Newsgroups: bionet.genome.arabidopsis
Subject: change of address for quail lab
Date: 1 Oct 1992 22:15:19 GMT
Organization: University of California, Berkeley
Distribution: world
NNTP-Posting-Host: mendel.berkeley.edu


Newsgroups: bionet.genome.arabidopsis
From: jaguey@forbt2.nrrc.ncsu.edu (Jose Chaparro)
Subject: Re: Using MAPMAKERin case of partial F2 lethality
Organization: North Carolina State University
Distribution: bionet
Date: Wed, 30 Sep 1992 14:44:09 GMT

In article <9209291857.AA05863@genbank.bio.net>, ANMR1@UORDB2.bitnet writes:
|> I would like to find out how to use the Lander MAPMAKER program to
|> analyze F2 intercross data for mapping when the homozygous recessive
|> for one marker is partially lethal. For example, when that marker gives a
|> 
|> distorted Mendelian ratio of (say) 7:1 in F2, instead of 3:1, due to partial
|> embryo lethality. I would appreciate if someone comments on this.
|> Thanks.
|> Animesh Ray
The first thing you should try is a chi square test for independence to test for associations between markers and the trait.  You cannot do this in mapMaker but it is possible to do it in a spread sheet program. If you have a large F2 population, and the molecular markers that you are testing for linkage do not exhibit a distorted segregation ratio, then you can analyse the data for linkage in mapmaker.  The linkage estimate will have a higher variance than normal, but you will know the general location of



 the lethal.
From: PLXZW@VAX.CCC.NOTTINGHAM.AC.UK
Newsgroups: bionet.genome.arabidopsis
Subject: Postdoc Appt-Mol.Plant Pathology
Date: 6 Oct 92 09:58:00 GMT
Distribution: bionet
Original-To: ARAB-GEN@UK.AC.DARESBURY

University of Nottingham
Department of Life Science

POSTDOCTORAL RESEARCH ASSISTANT
IN MOLECULAR PLANT PATHOLOGY

Applications are invited for a 3 year postdoctoral research post, 
funded by the AFRC, to work on molecular variation and the 
genetics of host specificity in Peronospora parasitica , a 
biotrophic 
fungal pathogen of crucifers.  The project will use RAPDs and 
RFLPs to fingerprint isolates from different host species and map 
pathogen genes of interest.  The postdoctoral scientist will join a 
small team working on the genetics of downy mildew fungi, but 
will also interact with the Plant Molecular Biology research 
group. 
Experience in appropriate molecular techniques is essential.  The 
salary will be on the RA 1A scale. 

Applications, including a cv. and the names of two referees 
should 
be sent ASAP to Dr. John Lucas, Department of Life Science, 
University of Nottingham, NG7 2RD.  Further details can be 
obtained from either Dr. Zoe Wilson (0602 513235) or Dr. John 
Lucas  (0602 513203).
From: BTNYDWM@MVS.UCC.OKSTATE.EDU
Newsgroups: bionet.genome.arabidopsis
Subject: Update on Mapping Survey
Date: 29 Sep 92 12:58:00 GMT
Distribution: bionet

To the Arabidopsis Community:

     The initial response to the mapping survey distributed
several weeks ago has been rather disappointing.  Please find
your copy of the survey and return it as soon as possible.
Most of you should have received two copies of the survey:
(1) by postal mail from the ABRC at Ohio State University;
and (2) by electronic mail from Mike Cherry at AAtDB
(curator@frodo.mgh.harvard.edu).  This duplication of effort
was designed to simplify your job in completing the survey and
encourage a greater response.  Completed forms need to be
received by October 15.  Results will be added immediately
to AAtDB and compiled for presentation at the upcoming Plant
Genome meeting in San Diego.  Please remember that the survey
includes two major sections: (1) linkage information on visible
and molecular markers; and (2) information on new gene symbols
currently being used in your laboratory.  Your response to both
sections is requested.  Please make an effort to contribute to
this important project.

Regards - David Meinke
From: tmb@faraday.clas.Virginia.EDU (Thomas M. Breeden)
Subject: Televised Symposium: Luciferase as a Real-Time Reporter of Gene Expression
Organization: University of Virginia
Distribution: na
Date: Mon, 28 Sep 1992 15:44:06 GMT

------------------------------------
The NSF Center for Biological Timing
and 
Promega Corporation
------------------------------------

Will Sponsor a Televised Symposium On:

     ***********************************************************
     *                                                         *
     *  Luciferase As A Real-Time Reporter of Gene Expression  *
     *                                                         *
     ***********************************************************

                       Friday, November 13, 1992
             1:00 P.M. to 3:30 P.M. Eastern Standard Time
             10:00 A.M. to 12:30 P.M. Pacific Standard Time

The keynote lectures will be televised via satellite to interested sites
within the United States:

Chairman: Dr. Margaret Shupnik, Center for Biological Timing and 
                          the Department of Medicine, University of Virginia

Speakers:

     The Application of Photon Counting Imaging for Biological Studies 
                  Dr. Robert Wick, Hamamatsu Corporation

     Firefly and Beetle Luciferases for Novel Gene Reporter Technology 
                  Dr. Keith Wood, Promega Corporation

     Monitoring Viral (HIV) Gene Expression in Mammalian Cells 
                  Dr. Michael White, Department of Biochemistry,
                            University of Oxford

     Dynamic Monitoring of Gene Expression in Higher Plants 
                  Dr. Steve Kay, Center for Biological Timing and 
                           the Department of Biology, University of Virginia

This program will be available, FREE OF CHARGE, to all sites in the U.S.
with satellite reception capability. We will provide you with complete
technical information and posters for local publicity. Please contact:

      Center for Biological Timing          Phone: (804) 982-5225
      Gilmer Hall                           Fax: (804) 982-5221
      University of Virginia                EMail: clock@virginia.edu
      Charlottesville, VA 22901

There will also be a limited number of spaces available for a
workshop/demonstration of Hamamatsu imaging systems on the morning of
Friday, November 13th. For registration information to attend the
symposium and demonstration on site, please contact the above address.
The onsite registration fee will be $75 for attendees from academic
institutions and $300 for corporate participants.

Additional information will also be posted on the BioTiming Bulletin Board,
on Internet (telnet minerva.acc.virginia.edu, login:biotiming).
--

            - Tom Breeden
              tmb@virginia.EDU      -> Internet
              tmb@virginia          -> BITNET
From: Quail@mendel.berkeley.edu ( Peter Quail)
Newsgroups: bionet.genome.arabidopsis
Subject: Change of E-mail address for Quail lab
Date: 2 Oct 1992 14:56:01 GMT
Organization: University of California, Berkeley
Distribution: world
NNTP-Posting-Host: mendel.berkeley.edu
Keywords: Pr <--> Pf


Greetings.

The E-mail address for Quail lab has been changed to:

	Quail@mendel.berkeley.edu


:-)  :-)  :-)
From: VARNUM@MOLBIO.UOREGON.EDU
Newsgroups: bionet.genome.arabidopsis
Subject: SEM on cauline and rosette leaves
Date: 5 Oct 92 22:52:18 GMT
Distribution: bionet

I am about to embark upon a series of SEM experiments but would first like 
to ask whether anyone has observed a difference between the epidermal cell 
layer of cauline and rosette leaves?  Any information would be appreciated.
                                   Susan Varnum
                                   varnum@molbio.uoregon.edu
From: S1DFV@ISUVAX.IASTATE.EDU
Newsgroups: bionet.genome.arabidopsis
Subject: job announcement
Date: 6 Oct 92 16:15:03 GMT
Distribution: bionet


Job Announcement:  Plant/Maize Molecular Geneticist

The Department of Zoology and Genetics at Iowa State University
seeks applicants for a tenure-track postion at any academic level. 
Plant molecular biologists using genetic approaches will be given
special consideration.  Laboratory and greenhouse space are available
in the new molecular biology building, and generous start-up funds 
will be provided.  Modest teaching responsibilities are determined by
the interest and expertise of the individual.  Application deadline is 
November 15, 1992 or until position is filled.  Send a curriculum vitae,
a description of future research, and three letters of reference to:
Alan G. Atherly, 2216 Molecular Biology Building, Iowa State University,
Ames, IA  50011
From: 21847CRS@MSU.EDU ("Chris.Somerville")
Newsgroups: bionet.genome.arabidopsis
Subject: Arabidopsis Information Service
Date: 6 Oct 92 02:48:00 GMT
Distribution: bionet


 Rob McClung asked about the fate of the Arabidopsis Information Service.
This journal stopped when Dr. Kranz retired last year.  However, there are
plans afoot to launch a successor and several colleagues around the world have
agreed to serve as editors. The Ohio Stock Center has offered to be the
publisher. Therefore, I hope that by next summer at the latest we will have
something in place.  We feel a bit nervous about this because several calls
for interest last year were greeted with muted enthusiasm.  There are already
too many journals and this newsgroup apparently satisfies many of the needs
for news (and with the MGH Gopher, also provides and archive of methods etc).

Regarding old copies of the AIS: I think the only solution is that I will
donate my copy of the entire series of AIS volumes to the Ohio Stock Center
and they can take responsibility for sending out xerox copies of articles.
Contact them if there is something you really need.