GreatNorthCollective/greatnorth-canada-federal-laws-text huggingface dataset:
Hazardous Products Regulations — (a)
A chemical under pressure that (a) contains > 1.0% flammable components, by mass, and has a heat of combustion < 20 kJ/g; or (b) contains < 85.0% flammable components, by mass, and has a heat of combustion ≥ 20 kJ/g
Hazardous Products Regulations — (a)
(a) contains > 1.0% flammable components, by mass, and has a heat of combustion < 20 kJ/g; or
Hazardous Products Regulations — (b)
(b) contains < 85.0% flammable components, by mass, and has a heat of combustion ≥ 20 kJ/g
Hazardous Products Regulations — 8.1
Definitions 8.1 The following definitions apply in this Subpart. acute toxicant means a mixture or substance that is liable to cause acute toxicity, or a mixture or substance that, upon contact with water, releases a gaseous substance that is liable to cause acute toxicity. ( toxique aigu ) acute toxicity refers to serious adverse health effects, including death, occurring following (a) oral or dermal administration of a single dose of a mixture or substance, or multiple doses given within 24 hours; or (b) an inhalation exposure to a mixture or substance of four hours or of a duration that is converted to four hours in accordance with subsection 8.1.1(4). ( toxicité aiguë ) dust means solid particles that are suspended in a gas, usually air. ( poussières ) mist means liquid droplets that are suspended in the air. ( brouillard ) SOR/2022-272, s. 38
Hazardous Products Regulations — Hazardous Products Regulations
acute toxicant means a mixture or substance that is liable to cause acute toxicity, or a mixture or substance that, upon contact with water, releases a gaseous substance that is liable to cause acute toxicity. ( toxique aigu )
Hazardous Products Regulations — (a)
acute toxicity refers to serious adverse health effects, including death, occurring following (a) oral or dermal administration of a single dose of a mixture or substance, or multiple doses given within 24 hours; or (b) an inhalation exposure to a mixture or substance of four hours or of a duration that is converted to four hours in accordance with subsection 8.1.1(4). ( toxicité aiguë )
Hazardous Products Regulations — Hazardous Products Regulations
dust means solid particles that are suspended in a gas, usually air. ( poussières )
Hazardous Products Regulations — Hazardous Products Regulations
mist means liquid droplets that are suspended in the air. ( brouillard )
Hazardous Products Regulations — 8.1.1
LD 50 or LC 50 — associated range 8.1.1 (1) An acute toxicant that is a substance is classified, with respect to each applicable route of exposure, in a category of this hazard class in accordance with the tables to subsection (3) if it has an LD 50 by the oral or dermal exposure route, or an LC 50 by the inhalation exposure route, that falls into one of the ranges indicated in the applicable table to that subsection. Contact with water — gaseous substance (2) If an acute toxicant that is a substance is not classified in accordance with subsection (1) with respect to the inhalation route of exposure in a category of this hazard class in accordance with Table 3 to subsection (3) and, upon contact with water, the acute toxicant releases a gaseous substance that has an LC 50 that falls into one of the ranges indicated in that table, it is classified in accordance with that table with regard to that range. LD 50 or LC 50 not available (3) If an LD 50 by the oral or dermal exposure route or an LC 50 by the inhalation exposure route is not available, an acute toxicity point estimate must be established in accordance with the table to section 8.1.7, and the acute toxicant must be classified based on that acute toxicity point estimate, with respect to each applicable route of exposure, in a category of this hazard class in accordance with the following tables: TABLE 1 Oral Exposure Route Column 1 Column 2 Item Category Ranges for LD 50 or for Acute Toxicity Point Estimates (mg/kg body weight) 1 Acute Toxicity (Oral) — Category 1 ≤ 5 2 Acute Toxicity (Oral) — Category 2 > 5 and ≤ 50 3 Acute Toxicity (Oral) — Category 3 > 50 and ≤ 300 4 Acute Toxicity (Oral) — Category 4 > 300 and ≤ 2000 TABLE 2 Dermal Exposure Route Column 1 Column 2 Item Category Ranges for LD 50 or for Acute Toxicity Point Estimates (mg/kg body weight ) 1 Acute Toxicity (Dermal) — Category 1 ≤ 50 2 Acute Toxicity (Dermal) — Category 2 > 50 and ≤ 200 3 Acute Toxicity (Dermal) — Category 3 > 200 and ≤ 1000 4 Acute Toxicity (Dermal) — Category 4 > 1000 and ≤ 2000 TABLE 3 Inhalation Exposure Route Column 1 Column 2 Column 3 Column 4 Ranges for LC 50 or for Acute Toxicity Point Estimates Item Category Gases (ppmV) Vapours (mg/l) Dusts and Mists (mg/l) 1 Acute Toxicity (Inhalation) — Category 1 ≤ 100 ≤ 0.5 ≤ 0.05 2 Acute Toxicity (Inhalation) — Category 2 > 100 and ≤ 500 > 0.5 and ≤ 2 > 0.05 and ≤ 0.5 3 Acute Toxicity (Inhalation) — Category 3 > 500 and ≤ 2500 > 2 and ≤ 10 > 0.5 and ≤ 1 4 Acute Toxicity (Inhalation) — Category 4 > 2500 and ≤ 20 000 > 10 and ≤ 20 > 1 and ≤ 5 One-hour exposure period (4) For the purposes of Table 3 to subsection (3), the LC 50 is based on a four-hour exposure period. If existing acute inhalation toxicity data have been generated according to a one-hour exposure period, the LC 50 for gases and vapours must be divided by two, and the LC 50 for dusts and mists must be divided by four. SOR/2022-272, s. 39
Hazardous Products Regulations — 8.1.2
Order of provisions 8.1.2 (1) The classification of a mixture as an acute toxicant in a category of this hazard class must proceed in accordance with the order of sections 8.1.3 to 8.1.6. Concentrations for the purpose of classification (2) Only ingredients present at concentrations equal to or greater than the concentration limit of 1.0% — w/w for solids, liquids, dusts, mists and vapours and v/v for gases — must be considered for the purpose of classification.
Hazardous Products Regulations — 8.1.3
Data available for mixture as a whole 8.1.3 If data of the types referred to in subparagraphs 2.1(a)(i) to (iv) are available for the mixture as a whole, the mixture must be classified as an acute toxicant in accordance with section 8.1.1.
Hazardous Products Regulations — 8.1.4
Data available for use of bridging principles 8.1.4 If data are available to enable the characterization of the mixture as an acute toxicant, in accordance with the bridging principles referred to in subsections 2.3(3) to (8), the mixture must be classified in a category of this hazard class in accordance with those subsections.
Hazardous Products Regulations — 8.1.5
Data available for all ingredients 8.1.5 If data are available for all ingredients in the mixture, the mixture must be classified as an acute toxicant in accordance with section 8.1.1 using the ATE of the mixture that is determined in respect of each applicable route of exposure by the following formula: ATE subscript mix is equal to 100 divided by, opening square bracket, the summation, represented by the capital sigma symbol, from n, of the series capital C, subscript i, divided by ATE, subscript i, closing square bracket. where ATE mix is the ATE of the mixture determined using this formula; C i is the concentration of ingredient i; n is the number of ingredients and i is running from 1 to n; ATE i is the ATE of ingredient i, which is either (a) the LD 50 or the LC 50 based on or converted to a four-hour exposure period, for i, or (b) if the LD 50 or the LC 50 is unavailable, the acute toxicity point estimate established for i in accordance with the table to section 8.1.7; and i is each ingredient in the mixture with (a) an ATE within the ranges set out in the applicable table to subsection 8.1.1(3), (b) an oral or dermal LD 50 greater than 2000 mg/kg body weight but less than or equal to 5000 mg/kg body weight, or (c) an LC 50 based on or converted to a four-hour exposure period within a range having an amplitude comparable to the one in paragraph (b).
Hazardous Products Regulations — 8.1.6
Data not available for all ingredients 8.1.6 If the ATE is not available for one or more ingredients of the mixture, the mixture must be classified as an acute toxicant in accordance with section 8.1.1 using the ATE of the mixture that is determined in respect of each applicable route of exposure according to the following: (a) if data permit the ATE to be estimated for each of those ingredients in accordance with established scientific principles, the formula in section 8.1.5 must be used; (b) if data do not permit the ATE to be estimated for an ingredient in accordance with established scientific principles, and the concentration of the ingredient in the mixture is equal to or greater than the concentration limit of 1.0%, the mixture is classified based only on the ingredients having an ATE, such that (i) if the total concentration of all ingredients with unknown acute toxicity is less than or equal to 10.0% of the mixture, the formula in section 8.1.5 must be used, or (ii) if the total concentration of all ingredients with unknown acute toxicity is greater than 10.0% of the mixture, the following formula must be used: ATE subscript mix is equal to the quotient of the numerator of 100 minus, opening parenthesis, the summation, represented by the capital sigma symbol, of the series capital C, subscript unknown, if the value of C is greater than 10.0%, closing parenthesis, divided by the following denominator: opening square bracket, the summation, represented by the symbol capital sigma, from n, of the series capital C, subscript i, divided by ATE, subscript i, closing square bracket. where ATE mix is the ATE of the mixture determined using this formula, C i is the concentration of ingredient i, C unknown is the concentration of ingredients i with unknown ATE values, n is the number of ingredients and i is running from 1 to n, ATE i is the ATE of ingredient i, which is either (a) the LD 50 or the LC 50 based on or converted to a four-hour exposure period, for i, or (b) if the LD 50 or the LC 50 is unavailable, the acute toxicity point estimate established for i in accordance with the table to section 8.1.7, and i is each ingredient in the mixture with (a) an ATE within the ranges set out in the applicable table to subsection 8.1.1(3), (b) an oral or dermal LD 50 greater than 2000 mg/kg body weight but less than or equal to 5000 mg/kg body weight, or (c) an LC 50 based on or converted to a four-hour exposure period within a range having an amplitude comparable to the one in paragraph (b).
Hazardous Products Regulations — 8.1.7
Conversion from range to point estimate 8.1.7 (1) If a formula in section 8.1.5 or 8.1.6 is used, an acute toxicity point estimate must be determined, in accordance with the table to subsection (2), for each ingredient for which only that ingredient’s classification category or experimentally obtained acute toxicity range is available. More than one range (2) If the experimentally obtained acute toxicity range for an ingredient does not fall entirely within any of the ranges set out in column 2 of the following table, the converted acute toxicity point estimate for that ingredient for the purposes of column 3 is the lowest value of the experimentally obtained acute toxicity range. TABLE Column 1 Column 2 Column 3 Item Exposure Routes Classification Category and Associated Experimentally Obtained Acute Toxicity Range Minimum and Maximum Values Converted Acute Toxicity Point Estimate 1 Oral (mg/kg body weight) 0 < Category 1 ≤ 5 5 < Category 2 ≤ 50 50 < Category 3 ≤ 300 300 < Category 4 ≤ 2000 0.5 5 100 500 2 Dermal (mg/kg body weight) 0 < Category 1 ≤ 50 50 < Category 2 ≤ 200 200 < Category 3 ≤ 1000 1000 < Category 4 ≤ 2000 5 50 300 1100 3 Inhalation (gases) (ppmV) 0 < Category 1 ≤ 100 100 < Category 2 ≤ 500 500 < Category 3 ≤ 2500 2500 < Category 4 ≤ 20 000 10 100 700 4500 4 Inhalation (vapours) (mg/l) 0 < Category 1 ≤ 0.5 0.5 < Category 2 ≤ 2.0 2.0 < Category 3 ≤ 10.0 10.0 < Category 4 ≤ 20.0 0.05 0.5 3 11 5 Inhalation (dust/mist) (mg/l) 0 < Category 1 ≤ 0.05 0.05 < Category 2 ≤ 0.5 0.5 < Category 3 ≤ 1.0 1.0 < Category 4 ≤ 5.0 0.005 0.05 0.5 1.5 SOR/2022-272, s. 40
Hazardous Products Regulations — 8.2
Definitions 8.2 The following definitions apply in this Subpart. skin corrosion means the production of irreversible damage to the skin, namely, visible necrosis through the epidermis and into the dermis, occurring after exposure to a mixture or substance, and includes ulcers, bleeding, bloody scabs and, within a 14-day observation period, discoloration due to blanching of the skin, complete areas of alopecia, and scars. ( corrosion cutanée ) skin-corrosive means, in relation to a mixture or substance, liable to cause skin corrosion. ( corrosif pour la peau ) skin-irritant means, in relation to a mixture or substance, liable to cause skin irritation. ( irritant pour la peau ) skin irritation means the production of reversible damage to the skin occurring after exposure to a mixture or substance. ( irritation cutanée ) SOR/2022-272, s. 41
Hazardous Products Regulations — Hazardous Products Regulations
skin corrosion means the production of irreversible damage to the skin, namely, visible necrosis through the epidermis and into the dermis, occurring after exposure to a mixture or substance, and includes ulcers, bleeding, bloody scabs and, within a 14-day observation period, discoloration due to blanching of the skin, complete areas of alopecia, and scars. ( corrosion cutanée )
Hazardous Products Regulations — Hazardous Products Regulations
skin-corrosive means, in relation to a mixture or substance, liable to cause skin corrosion. ( corrosif pour la peau )
Hazardous Products Regulations — Hazardous Products Regulations
skin-irritant means, in relation to a mixture or substance, liable to cause skin irritation. ( irritant pour la peau )
Hazardous Products Regulations — Hazardous Products Regulations
skin irritation means the production of reversible damage to the skin occurring after exposure to a mixture or substance. ( irritation cutanée )
Hazardous Products Regulations — 8.2.1
Order of provisions 8.2.1 The classification of a skin-corrosive substance or a skin-irritant substance in a category or subcategory of this hazard class must proceed in accordance with the order of sections 8.2.2 to 8.2.7, unless, after applying subsections 8.2.2(1) to (3), the substance is not classified further to subsection 8.2.2(4).
Hazardous Products Regulations — (a)
A substance (a) that, according to human data, is skin-irritant; or (b) in respect of which animal data reveal (i) in the case of data acquired from a test performed in accordance with the OECD Guideline for the Testing of Chemicals, No. 404, entitled Acute Dermal Irritation/Corrosion , as amended from time to time, a mean score of ≥ 2.3 and ≤ 4.0 for erythema and eschar or for edema in at least two of three animals from gradings at 24, 48 and 72 hours after patch removal or, if reactions are delayed, from gradings on three consecutive days after the onset of skin reactions, (ii) in the case of data acquired from a scientifically validated method, inflammation, namely, local alopecia, hyperkeratosis, hyperplasia and scaling, that persists to the end of the observation period specified by the method in at least two animals, or (iii) in the case of data acquired from a scientifically validated method, evidence of severe skin irritation in only one animal
Hazardous Products Regulations — (a)
(a) that, according to human data, is skin-irritant; or
Hazardous Products Regulations — (b)
(b) in respect of which animal data reveal (i) in the case of data acquired from a test performed in accordance with the OECD Guideline for the Testing of Chemicals, No. 404, entitled Acute Dermal Irritation/Corrosion , as amended from time to time, a mean score of ≥ 2.3 and ≤ 4.0 for erythema and eschar or for edema in at least two of three animals from gradings at 24, 48 and 72 hours after patch removal or, if reactions are delayed, from gradings on three consecutive days after the onset of skin reactions, (ii) in the case of data acquired from a scientifically validated method, inflammation, namely, local alopecia, hyperkeratosis, hyperplasia and scaling, that persists to the end of the observation period specified by the method in at least two animals, or (iii) in the case of data acquired from a scientifically validated method, evidence of severe skin irritation in only one animal
Hazardous Products Regulations — (i)
(i) in the case of data acquired from a test performed in accordance with the OECD Guideline for the Testing of Chemicals, No. 404, entitled Acute Dermal Irritation/Corrosion , as amended from time to time, a mean score of ≥ 2.3 and ≤ 4.0 for erythema and eschar or for edema in at least two of three animals from gradings at 24, 48 and 72 hours after patch removal or, if reactions are delayed, from gradings on three consecutive days after the onset of skin reactions,
Hazardous Products Regulations — (ii)
(ii) in the case of data acquired from a scientifically validated method, inflammation, namely, local alopecia, hyperkeratosis, hyperplasia and scaling, that persists to the end of the observation period specified by the method in at least two animals, or
Hazardous Products Regulations — (iii)
(iii) in the case of data acquired from a scientifically validated method, evidence of severe skin irritation in only one animal
Hazardous Products Regulations — 8.2.3
Other skin data from animals 8.2.3 A substance for which there are animal data on dermal exposure, acquired from a scientifically validated method, that have not been purposely generated and that demonstrate that the substance is skin-corrosive or skin-irritant is classified, respectively, in the category “Skin Corrosion — Category 1” or the category “Skin Irritation — Category 2”.
Hazardous Products Regulations — 8.2.4
In vitro or ex vivo data 8.2.4 A substance for which the data, in vitro or ex vivo , acquired from a scientifically validated method for the evaluation of skin corrosion or skin irritation demonstrate that the substance is skin-corrosive or skin-irritant is classified, respectively, in the category “Skin Corrosion — Category 1” or the category “Skin Irritation — Category 2”.
Hazardous Products Regulations — 8.2.5
pH 8.2.5 A substance for which the pH is less than or equal to two or equal to or greater than 11.5 is classified in the category “Skin Corrosion — Category 1”, unless an assessment of alkali or acid reserve performed in accordance with established scientific principles supports the conclusion that it need not be classified as a skin-corrosive substance on the basis of its pH.
Hazardous Products Regulations — 8.2.6
Structure-activity relationship — skin corrosion 8.2.6 (1) A substance for which a structure-activity relationship, established in accordance with established scientific principles, supports the conclusion that the substance must be classified in the category “Skin Corrosion — Category 1” is classified in that category. Structure-activity relationship — skin irritation (2) A substance for which a structure-activity relationship, established in accordance with established scientific principles, supports the conclusion that the substance must be classified in the category “Skin Irritation — Category 2” is classified in that category.
Hazardous Products Regulations — 8.2.7
Totality of available data 8.2.7 A substance for which an evaluation of the totality of available data, performed in accordance with established scientific principles, supports the conclusion that the substance is skin-corrosive or skin-irritant is classified, respectively, in the category “Skin Corrosion — Category 1” or the category “Skin Irritation — Category 2”.
Hazardous Products Regulations — 8.2.8
Order of provisions 8.2.8 The classification of a mixture as skin-corrosive or as skin-irritant in a category or subcategory of this hazard class must proceed in accordance with the order of sections 8.2.9 to 8.2.11.
Hazardous Products Regulations — 8.2.9
Data available for mixture as a whole 8.2.9 (1) If data of the types referred to in subparagraphs 2.1(a)(i) to (iv) are available for the mixture as a whole, the mixture must be classified in accordance with the order of sections 8.2.2 to 8.2.7, unless under subsection 8.2.2(4) the mixture need not be classified. Data available for mixture as a whole — sections 8.2.10 and 8.2.11 (2) If data of the types referred to in subparagraphs 2.1(a)(i) to (iv) are available for the mixture as a whole, but the mixture cannot be classified further to subsections 8.2.2(1) to (3) or sections 8.2.3 to 8.2.7, its classification in a category or subcategory of this hazard class must proceed in accordance with the order of sections 8.2.10 and 8.2.11.
Hazardous Products Regulations — 8.2.10
Data available for use of bridging principles 8.2.10 If data are available to enable the characterization of the mixture as a skin-corrosive mixture or a skin-irritant mixture, in accordance with the bridging principles referred to in subsections 2.3(3) to (8), the mixture must be classified in a category or subcategory of this hazard class in accordance with those subsections.
Hazardous Products Regulations — 8.2.11
ed in the subcategory “Skin Corrosion ─ Category 1C”; (b) if the sum of concentrations of ingredients classified in the category “Skin Corrosion — Category 1”, ingredients classified in the subcategory “Skin Corrosion — Category 1A”, ingredients classified in the subcategory “Skin Corrosion — Category 1B” and ingredients classified in the subcategory “Skin Corrosion — Category 1C” is equal to or greater than 1.0% but less than 5.0%, the mixture is classified in the category “Skin Irritation — Category 2”; (c) if the sum of concentrations of ingredients classified in the category “Skin Irritation — Category 2” is equal to or greater than 10.0%, the mixture is classified in the category “Skin Irritation — Category 2”; or (d) if the sum of the results of the following subparagraphs is equal to or greater than 10.0%, the mixture is classified in the category “Skin Irritation — Category 2”: (i) 10 times the sum of concentrations of ingredients classified in the category “Skin Corrosion — Category 1”, ingredients classified in the subcategory “Skin Corrosion — Category 1A”, ingredients classified in the subcategory “Skin Corrosion — Category 1B” and ingredients classified in the subcategory “Skin Corrosion — Category 1C”, and (ii) the sum of concentrations of ingredients classified in the category “Skin Irritation — Category 2”. Mixtures containing particular ingredients (3) A mixture is classified in a category of this hazard class in accordance with the following table if it contains one or more substances, such as acids, bases, inorganic salts, aldehydes, phenols or surfactants, which could be corrosive or irritant at concentrations below the concentration limits set out in subsection (2) and at least one ingredient with a concentration that is above the concentration limits set out below: TABLE Column 1 Column 2 Column 3 Item Category Ingredient Concentration Limits 1 Skin Corrosion — Category 1 Acid with pH ≤ 2 ≥ 1.0% 2 Skin Corrosion — Category 1 Base with pH ≥ 11.5 ≥ 1.0% 3 Skin Corrosion — Category 1 Other ingredients classified in the category “Skin Corrosion — Category 1” ≥ 1.0% 4 Skin Irritation — Category 2 Other ingredients classified in the category “Skin Irritation — Category 2”, including acids and bases ≥ 3.0% SOR/2022-272, s. 43
Hazardous Products Regulations — 8.3
Definitions 8.3 The following definitions apply in this Subpart. eye irritation means the production of changes in the eye after exposure of the eye to a mixture or substance that are fully reversible within an observation period of 21 days after that exposure. ( irritation oculaire ) serious eye damage means the production of tissue damage in the eye or serious physical decay of vision, occurring after exposure of the eye to a mixture or substance, (a) for which data demonstrate that it is irreversible; or (b) that is not fully reversible within an observation period of 21 days after that exposure. ( lésion oculaire grave ) SOR/2022-272, s. 44