Reference number : GC-2017-Q3-00544, amendment number : , agreement type : G, recipient legal name : Li, Feng (Brock University), recipient country : CA, recipient province : nan, recipient city : Ontario, recipient postal code : nan, program name english : Engage Grants for universities, program name french : Subventions d'engagement partenarial pour les universités, program purpose english : Point-of-care tests (POCT) are simple medical tests that can bring complex disease diagnostic and screening tests currently performed at centralized facilities to patients bedside and thus are envisioned to significantly improve the quality of healthcare. However, only a few POCT systems have been commercialized for diagnosis, prognosis, and screening of devastating diseases, such as bacteria and virus infections. This proposed research will work towards design, fabrication and testing of a smartphonebased POCT diagnostic system that detects bacterial and viral pathogens from patient samples by identifying species-specific genetic sequences using color. Leveraging the advantages of DNA-mediated ultrafast color generation and accurate color identification using the Nix Color Sensor, this system will analyze clinical sample for major infectious diseases in less than one hour by just using a smartphone and thus allow physicians to screen patients accurately in a non-invasive manner during a single visit. If successful, the simple and inexpensive smartphone-based tests, which are currently not available, can be easily incorporated into a routine physical checkup to screen patients before presentation of overt symptoms. Such early screening will hold great promise to enable personalized healthcare, improve quality of life, and decrease the financial costs associated with patient care., program purpose french : Point-of-care tests (POCT) are simple medical tests that can bring complex disease diagnostic and screening tests currently performed at centralized facilities to patients bedside and thus are envisioned to significantly improve the quality of healthcare. However, only a few POCT systems have been commercialized for diagnosis, prognosis, and screening of devastating diseases, such as bacteria and virus infections. This proposed research will work towards design, fabrication and testing of a smartphonebased POCT diagnostic system that detects bacterial and viral pathogens from patient samples by identifying species-specific genetic sequences using color. Leveraging the advantages of DNA-mediated ultrafast color generation and accurate color identification using the Nix Color Sensor, this system will analyze clinical sample for major infectious diseases in less than one hour by just using a smartphone and thus allow physicians to screen patients accurately in a non-invasive manner during a single visit. If successful, the simple and inexpensive smartphone-based tests, which are currently not available, can be easily incorporated into a routine physical checkup to screen patients before presentation of overt symptoms. Such early screening will hold great promise to enable personalized healthcare, improve quality of life, and decrease the financial costs associated with patient care., agreement title english : Development of ultrafast colorimetric assays and devices for integration into the Nix Color Sensor, agreement title french : Development of ultrafast colorimetric assays and devices for integration into the Nix Color Sensor, agreement number : EGP, agreement value : 25000.0, agreement start date : 2017-12-13, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada