Reference number : GC-2017-Q1-00248, amendment number : , agreement type : G, recipient legal name : Chiao, Mu (The University of British Columbia), recipient country : CA, recipient province : nan, recipient city : British Columbia|Colombie-Britannique, recipient postal code : nan, program name english : Collaborative Health Research Projects, program name french : Projets de recherche concertée sur la santé, program purpose english : In recent years, various optical microscopy techniques have been developed for nondestructive_x000D_
imaging of biological tissues, including optical coherence tomography, reflectancemode_x000D_
confocal microscopy, fluorescence-mode confocal microscopy, and multiphoton_x000D_
excitation microscopy. Each imaging modality has its own advantages and disadvantages._x000D_
Previously, confocal microscopy has shown progress in skin cancer imaging and_x000D_
demonstrated potential in other cancer diagnosis. However, moving confocal imaging_x000D_
modalities into endoscopy applications is challenging in that miniaturized catheter probes_x000D_
have to be developed to pass through the endoscope instrument channel that is a few_x000D_
millimeter diameter in size. In this research, we aim to use MEMES (Microelectromechanical_x000D_
Systems) technology to make a miniature confocal optical probe that will produce histologylike_x000D_
cross sectional images and 3D images of tissue in vivo for GI (gastrointestinal) cancer_x000D_
diagnosis., program purpose french : In recent years, various optical microscopy techniques have been developed for nondestructive_x000D_
imaging of biological tissues, including optical coherence tomography, reflectancemode_x000D_
confocal microscopy, fluorescence-mode confocal microscopy, and multiphoton_x000D_
excitation microscopy. Each imaging modality has its own advantages and disadvantages._x000D_
Previously, confocal microscopy has shown progress in skin cancer imaging and_x000D_
demonstrated potential in other cancer diagnosis. However, moving confocal imaging_x000D_
modalities into endoscopy applications is challenging in that miniaturized catheter probes_x000D_
have to be developed to pass through the endoscope instrument channel that is a few_x000D_
millimeter diameter in size. In this research, we aim to use MEMES (Microelectromechanical_x000D_
Systems) technology to make a miniature confocal optical probe that will produce histologylike_x000D_
cross sectional images and 3D images of tissue in vivo for GI (gastrointestinal) cancer_x000D_
diagnosis., agreement title english : Development of a confocal endoscope for gastrointestinal cancer diagnosis, agreement title french : Development of a confocal endoscope for gastrointestinal cancer diagnosis, agreement number : CHRPJ, agreement value : 311545.0, agreement start date : 2017-04-25, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year. (2017-2018 to 2020-2021), additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2020-2021), owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada