Reference number : GC-2017-Q4-01729, amendment number : , agreement type : G, recipient legal name : Sylvestre, Julien (Université de Sherbrooke), recipient country : CA, recipient province : nan, recipient city : Quebec|Québec, recipient postal code : nan, program name english : Engage Grants for universities, program name french : Subventions d'engagement partenarial pour les universités, program purpose english : Various containers, such as glass vials and plastic bags, are used in large quantities by the pharmaceutical_x000D_
industry to manufacture and distribute sterile products. Structural weaknesses or defects in these containers can_x000D_
compromise the integrity of the pharmaceutical products. When detected during the manufacturing phase,_x000D_
compromised products have to be discarded and result in significant monetary losses. When they go_x000D_
undetected, compromised products jeopardize patient safety. As a result, manufacturers of pharmaceutical_x000D_
products and suppliers of glass or plastic containers invest significant efforts to control the quality of containers_x000D_
and packaged products, before, during and after the manufacturing process. Many of the most important classes_x000D_
of defects are difficult to detect with conventional methods, such as optical inspection. Examples include_x000D_
hairline cracks or voids in the walls of glass vials, voids in plastic bag seals, glass vial walls or plastic bags that_x000D_
are too thin, and small glass particles mixed with the pharmaceutical product inside glass vials. The industry is_x000D_
therefore looking for other inspection technologies that could provide quality information which is orthogonal_x000D_
to what is provided by optical methods, to better detect hard-to-find defects. The main research challenges to be_x000D_
addressed through the project therefore include the use of quality control technologies for pharmaceutical_x000D_
containers based on acoustic microscopy, which have high sensitivity to defects, low false positive rates, and_x000D_
which are fast enough for high-volume manufacturing., program purpose french : Various containers, such as glass vials and plastic bags, are used in large quantities by the pharmaceutical_x000D_
industry to manufacture and distribute sterile products. Structural weaknesses or defects in these containers can_x000D_
compromise the integrity of the pharmaceutical products. When detected during the manufacturing phase,_x000D_
compromised products have to be discarded and result in significant monetary losses. When they go_x000D_
undetected, compromised products jeopardize patient safety. As a result, manufacturers of pharmaceutical_x000D_
products and suppliers of glass or plastic containers invest significant efforts to control the quality of containers_x000D_
and packaged products, before, during and after the manufacturing process. Many of the most important classes_x000D_
of defects are difficult to detect with conventional methods, such as optical inspection. Examples include_x000D_
hairline cracks or voids in the walls of glass vials, voids in plastic bag seals, glass vial walls or plastic bags that_x000D_
are too thin, and small glass particles mixed with the pharmaceutical product inside glass vials. The industry is_x000D_
therefore looking for other inspection technologies that could provide quality information which is orthogonal_x000D_
to what is provided by optical methods, to better detect hard-to-find defects. The main research challenges to be_x000D_
addressed through the project therefore include the use of quality control technologies for pharmaceutical_x000D_
containers based on acoustic microscopy, which have high sensitivity to defects, low false positive rates, and_x000D_
which are fast enough for high-volume manufacturing., agreement title english : Scalable Acoustic Microscopy for Pharmaceutical Applications, agreement title french : Scalable Acoustic Microscopy for Pharmaceutical Applications, agreement number : EGP, agreement value : 25000.0, agreement start date : 2018-03-22, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada