Reference number : GC-2017-Q3-00578, amendment number : , agreement type : G, recipient legal name : Hébert, Terence (McGill University)|Hébert, Terence (Université McGill), recipient country : CA, recipient province : nan, recipient city : Quebec|Québec, recipient postal code : nan, program name english : Engage Grants for universities, program name french : Subventions d'engagement partenarial pour les universités, program purpose english : The ability to image and record cellular processes in living animals represents one of the most powerful_x000D_
approaches in biological research. A variety of protein based optical indicators or "biosensors" have been used_x000D_
to report cellular processes in cultured cells. However, imaging these biosensors in live animals has_x000D_
traditionally been challenging, requiring costly transgenic animals and specialized microscopy equipment._x000D_
These obstacles can be overcome with the recent development of affordable fiber-optic imaging systems,_x000D_
together with improved genetically-engineered biosensors and viral delivery methods. This Engage proposal_x000D_
aims to develop a novel fiber-optic photon counting system that would provide an affordable tool for recording_x000D_
biosensor emissions in live animals., program purpose french : The ability to image and record cellular processes in living animals represents one of the most powerful_x000D_
approaches in biological research. A variety of protein based optical indicators or "biosensors" have been used_x000D_
to report cellular processes in cultured cells. However, imaging these biosensors in live animals has_x000D_
traditionally been challenging, requiring costly transgenic animals and specialized microscopy equipment._x000D_
These obstacles can be overcome with the recent development of affordable fiber-optic imaging systems,_x000D_
together with improved genetically-engineered biosensors and viral delivery methods. This Engage proposal_x000D_
aims to develop a novel fiber-optic photon counting system that would provide an affordable tool for recording_x000D_
biosensor emissions in live animals., agreement title english : Development of fiber-optic, fluorescence lifetime-based imaging system for in vivo measures of signalling events, agreement title french : Development of fiber-optic, fluorescence lifetime-based imaging system for in vivo measures of signalling events, agreement number : EGP, agreement value : 25000.0, agreement start date : 2017-11-08, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada