Reference number : GC-2017-Q1-00235, amendment number : , agreement type : G, recipient legal name : Freed, Darren (University of Alberta), recipient country : CA, recipient province : nan, recipient city : Alberta, recipient postal code : nan, program name english : Collaborative Health Research Projects, program name french : Projets de recherche concertée sur la santé, program purpose english : Cardiac transplantation remains the gold standard therapy for the definitive treatment of endstage_x000D_
heart failure. However the wider application of this life saving intervention is limited by_x000D_
the short supply of donor organs. Compounding this problem is a high frequency of poor heart_x000D_
function observed in the multi-organ donor, resulting in a low utilization rate of hearts that are_x000D_
offered. We are developing a device that will provide continuous warm blood-based perfusion_x000D_
of the donor heart, permitting optimal preservation of the organ as well as functional_x000D_
assessment., program purpose french : Cardiac transplantation remains the gold standard therapy for the definitive treatment of endstage_x000D_
heart failure. However the wider application of this life saving intervention is limited by_x000D_
the short supply of donor organs. Compounding this problem is a high frequency of poor heart_x000D_
function observed in the multi-organ donor, resulting in a low utilization rate of hearts that are_x000D_
offered. We are developing a device that will provide continuous warm blood-based perfusion_x000D_
of the donor heart, permitting optimal preservation of the organ as well as functional_x000D_
assessment., agreement title english : Development of an ex vivo heart perfusion system for pre-transplant preservation and evaluation of donor hearts, agreement title french : Development of an ex vivo heart perfusion system for pre-transplant preservation and evaluation of donor hearts, agreement number : CHRPJ, agreement value : 315794.0, agreement start date : 2017-04-25, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year. (2017-2018 to 2020-2021), additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2020-2021), owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada