Reference number : GC-2017-Q4-00445, amendment number : , agreement type : G, recipient legal name : DeGroot, Christopher (The University of Western Ontario), recipient country : CA, recipient province : nan, recipient city : Ontario, recipient postal code : nan, program name english : Engage Grants for universities, program name french : Subventions d'engagement partenarial pour les universités, program purpose english : A nebulizer is a type of drug delivery device that provides medication in the form of an aerosol that can be_x000D_
inhaled into the lungs and absorbed into the bloodstream. They are typically used to treat respiratory illnesses_x000D_
such as chronic obstructive pulmonary disorder and asthma. Nebulizers operate by taking a medication in_x000D_
liquid form, transforming it into small aerosol droplets of a particular size, and delivering those droplets to the_x000D_
mouth of the patient for inhalation. There are several different types of nebulizer, the most common of which is_x000D_
the jet nebulizer, which will be studied during the proposed project. These operate through the use of a_x000D_
high-speed jet of compressed gas, which entrains the liquid and converts it to an aerosol, typically by colliding_x000D_
the liquid droplets with a baffle._x000D_
This project seeks to provide a better understanding of the operation of jet nebulizers from a fluid mechanics_x000D_
perspective. To provide this understanding, a computational fluid dynamics (CFD) model will be developed to_x000D_
model the flow patterns in the device, and their role in the formation and delivery of aerosol particles. This will_x000D_
allow for optimization of nebulizer devices, which can lead to better utilization of the drug and shorter_x000D_
treatment times for patients. Ultimately, by improving the medical devices that treat respiratory illnesses, the_x000D_
patients' conditions can be better managed, allowing them to lead better lives., program purpose french : A nebulizer is a type of drug delivery device that provides medication in the form of an aerosol that can be_x000D_
inhaled into the lungs and absorbed into the bloodstream. They are typically used to treat respiratory illnesses_x000D_
such as chronic obstructive pulmonary disorder and asthma. Nebulizers operate by taking a medication in_x000D_
liquid form, transforming it into small aerosol droplets of a particular size, and delivering those droplets to the_x000D_
mouth of the patient for inhalation. There are several different types of nebulizer, the most common of which is_x000D_
the jet nebulizer, which will be studied during the proposed project. These operate through the use of a_x000D_
high-speed jet of compressed gas, which entrains the liquid and converts it to an aerosol, typically by colliding_x000D_
the liquid droplets with a baffle._x000D_
This project seeks to provide a better understanding of the operation of jet nebulizers from a fluid mechanics_x000D_
perspective. To provide this understanding, a computational fluid dynamics (CFD) model will be developed to_x000D_
model the flow patterns in the device, and their role in the formation and delivery of aerosol particles. This will_x000D_
allow for optimization of nebulizer devices, which can lead to better utilization of the drug and shorter_x000D_
treatment times for patients. Ultimately, by improving the medical devices that treat respiratory illnesses, the_x000D_
patients' conditions can be better managed, allowing them to lead better lives., agreement title english : Development of a Computational Fluid Dynamics Model of a Jet Nebulizer Device for Aerosol Drug Delivery, agreement title french : Development of a Computational Fluid Dynamics Model of a Jet Nebulizer Device for Aerosol Drug Delivery, agreement number : EGP, agreement value : 25000.0, agreement start date : 2018-02-07, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada