Reference number : 172-2025-2026-Q4-1041349, amendment number : , agreement type : C, recipient legal name : Kapoose Creek Bio Corporation, recipient country : CA, recipient province : BC, recipient city : Vancouver|Vancouver, recipient postal code : V6H 3Y4, program name english : Industrial Research Assistance Program, program name french : Programme d’aide à la recherche industrielle, program purpose english : The purpose of Industrial Research Assistance Program Contributions to Firms is to provide support that assists small and medium-sized enterprises (SMEs) to advance their innovation knowledge and ability to innovate, grow through innovation and stimulate wealth creation for Canada., program purpose french : Les contributions versées aux entreprises en vertu du Programme d’aide à la recherche industrielle ont pour objectif d’apporter un soutien aux petites et moyennes entreprises (PME) afin qu’elles puissent approfondir leurs connaissances en matière d’innovation et renforcer leur capacité d’innovation, de croissance et de création de richesse pour le Canada., agreement title english : AI-Enabled Phenotypic Platform for Chemical Threat Assessment, agreement title french : AI-Enabled Phenotypic Platform for Chemical Threat Assessment, agreement number : 1041349, agreement value : 700000.0, agreement start date : 2026-02-01, agreement end date : 2027-08-02, description english : Kapoose Creek Bio will adapt our existing AI-enabled phenotypic profiling platform for chemical threat assessment. Unlike chemistry-first detection that requires knowing what to look for, our activity-based approach identifies biological mechanism of action regardless of chemical novelty detecting even never-before-seen agents, such as novel derivatives that would evade traditional methods. The platform uses high-content cell imaging combined with Random Forest machine learning, leveraging a training set of 13,000+ bioactive compounds with known activity and mechanism. We will build a reference atlas of ~100 threat-relevant agents to further train mechanism classification. This capability will provide actionable intelligence within 48h., description french : Kapoose Creek Bio will adapt our existing AI-enabled phenotypic profiling platform for chemical threat assessment. Unlike chemistry-first detection that requires knowing what to look for, our activity-based approach identifies biological mechanism of action regardless of chemical novelty detecting even never-before-seen agents, such as novel derivatives that would evade traditional methods. The platform uses high-content cell imaging combined with Random Forest machine learning, leveraging a training set of 13,000+ bioactive compounds with known activity and mechanism. We will build a reference atlas of ~100 threat-relevant agents to further train mechanism classification. This capability will provide actionable intelligence within 48h., expected results english : The expected results and outcomes of NRC Industrial Research Assistance Program is focused on growing small and medium-sized enterprises (SMEs) through innovation and wealth creation for Canada., expected results french : Les résultats attendus du Programme d’aide à la recherche industrielle du CNRC sont axés sur la croissance des petites et moyennes entreprises (PME) grâce à l’innovation et à la création de richesse pour le Canada., additional information english : nan, additional information french : nan, owner organization : nrc-cnrc, owner organization title : National Research Council Canada | Conseil national de recherches Canada