Reference number : GC-2017-Q4-01562, amendment number : , agreement type : G, recipient legal name : Rousseaux, Sophie (University of Toronto), recipient country : CA, recipient province : nan, recipient city : Ontario, recipient postal code : nan, program name english : Engage Grants for universities, program name french : Subventions d'engagement partenarial pour les universités, program purpose english : The cyclopropylamine motif is found in numerous pharmaceuticals and agrochemicals. Therefore, methods to_x000D_
prepare these compounds are highly desirable. This Engage Grant will explore a new method to prepare_x000D_
cyclopropylamines from readily accessible starting materials based on recent results obtained by the Rousseaux_x000D_
group in this area._x000D_
Inception Sciences Canada has found that introduction of a cyclopropylamine motif in one of their small_x000D_
molecule therapeutics is beneficial for overall potency while also leading to desirable metabolic properties. The_x000D_
method developed by the Rousseaux group in the context of this Engage Grant will enable Inception Sciences_x000D_
to rapidly construct a large library of cyclopropylamines and facilitate the synthesis of analogs., program purpose french : The cyclopropylamine motif is found in numerous pharmaceuticals and agrochemicals. Therefore, methods to_x000D_
prepare these compounds are highly desirable. This Engage Grant will explore a new method to prepare_x000D_
cyclopropylamines from readily accessible starting materials based on recent results obtained by the Rousseaux_x000D_
group in this area._x000D_
Inception Sciences Canada has found that introduction of a cyclopropylamine motif in one of their small_x000D_
molecule therapeutics is beneficial for overall potency while also leading to desirable metabolic properties. The_x000D_
method developed by the Rousseaux group in the context of this Engage Grant will enable Inception Sciences_x000D_
to rapidly construct a large library of cyclopropylamines and facilitate the synthesis of analogs., agreement title english : Development of a One-Pot Procedure for the Synthesis of Cyclopropylamines, agreement title french : Development of a One-Pot Procedure for the Synthesis of Cyclopropylamines, agreement number : EGP, agreement value : 25000.0, agreement start date : 2018-03-07, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada