Reference number : GC-2017-Q2-00476, amendment number : , agreement type : G, recipient legal name : Hein, Jason (The University of British Columbia), recipient country : CA, recipient province : nan, recipient city : British Columbia|Colombie-Britannique, recipient postal code : nan, program name english : Engage Plus Grants for Universities, program name french : Subvention d'engagement partenarial Plus pour les universités, program purpose english : The ability to visualize a chemical reaction in real-time is a very powerful and much needed tool. Real-time_x000D_
feedback using this approach would allow chemical researchers to identify new transformations and study new_x000D_
catalysts. At the same time, this technology is needed to safely control production and manufacturing_x000D_
processes. Many analytical techniques have been adapted to probe chemical reactions in real-time, however,_x000D_
most have serious restrictions on the kind of reaction that can be investigated, or require significant effort to_x000D_
prepare samples for visualization. This is especially true for analysis by Nuclear Magnetic Resonance (NMR)._x000D_
Despite the wealth of kinetic and structural information available through this technique, broad application has_x000D_
been hampered by the technical challenges of sampling and analysis. The challenge is to design and integrate_x000D_
an efficient workflow that allows any reaction to be probed quickly, accurately and with minimal perturbation_x000D_
of the system under study. This project will develop new technology through a partnership with Nanalysis and_x000D_
researchers at the University of British Columbia. This team has separately developed new NMR hardware_x000D_
(Nanalysys) and automated robotic sampling (UBC) that, when combined, will provide a new broadly_x000D_
applicable NMR analysis technique., program purpose french : The ability to visualize a chemical reaction in real-time is a very powerful and much needed tool. Real-time_x000D_
feedback using this approach would allow chemical researchers to identify new transformations and study new_x000D_
catalysts. At the same time, this technology is needed to safely control production and manufacturing_x000D_
processes. Many analytical techniques have been adapted to probe chemical reactions in real-time, however,_x000D_
most have serious restrictions on the kind of reaction that can be investigated, or require significant effort to_x000D_
prepare samples for visualization. This is especially true for analysis by Nuclear Magnetic Resonance (NMR)._x000D_
Despite the wealth of kinetic and structural information available through this technique, broad application has_x000D_
been hampered by the technical challenges of sampling and analysis. The challenge is to design and integrate_x000D_
an efficient workflow that allows any reaction to be probed quickly, accurately and with minimal perturbation_x000D_
of the system under study. This project will develop new technology through a partnership with Nanalysis and_x000D_
researchers at the University of British Columbia. This team has separately developed new NMR hardware_x000D_
(Nanalysys) and automated robotic sampling (UBC) that, when combined, will provide a new broadly_x000D_
applicable NMR analysis technique., agreement title english : Combined HPLC-NMR reaction progress monitoring using the NMReady., agreement title french : Combined HPLC-NMR reaction progress monitoring using the NMReady., agreement number : EGP2, agreement value : 12500.0, agreement start date : 2017-08-23, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada