Reference number : GC-2017-Q4-01731, amendment number : , agreement type : G, recipient legal name : Szatmari, George (Université de Montréal), recipient country : CA, recipient province : nan, recipient city : Quebec|Québec, recipient postal code : nan, program name english : Engage Grants for universities, program name french : Subventions d'engagement partenarial pour les universités, program purpose english : Cosenzae myxofaciens is a bacterium strongly related to other Proteus species, such as P.mirabilis._x000D_
C.myxofaciens is a strain of industrial importance, mostly for its ability to produce large quantities of cellulose_x000D_
in a short time period. The cellulose produced by this bacterium is of higher purity than that obtained from_x000D_
plant sources, which requires further treatments to remove hemicellulose and lignin. In addition, increased_x000D_
demand for plant-based cellulose will ultimately lead to deforestation and other environmental concerns. The_x000D_
production of bacterial cellulose overcomes these problems, as bacteria can be grown in large quantities using_x000D_
simple carbon sources, including various types of industrial wastes and other by-products. Bacterial cellulose_x000D_
is currently used by the electronic, food and biomedical industries. Traditionally, bacterial cellulose has been_x000D_
produced by Gluconeoacetobacter xylinus, a bacteria which requires oxygen to grow. C.myxofaciens has been_x000D_
recently revealed to be a better candidate for cellulose production, as this bacteria can grow in both the_x000D_
presence and absence of oxygen, making it more suitable for growth in large-scale industrial fermentors. The_x000D_
aim of this proposal is to develop molecular genetics tools to manipulate this organism to better understand its_x000D_
regulation of cellulose biosynthesis, with the ultimate goal of developing safe, stable, cellulose-overproducing_x000D_
strains for industrial applications., program purpose french : Cosenzae myxofaciens is a bacterium strongly related to other Proteus species, such as P.mirabilis._x000D_
C.myxofaciens is a strain of industrial importance, mostly for its ability to produce large quantities of cellulose_x000D_
in a short time period. The cellulose produced by this bacterium is of higher purity than that obtained from_x000D_
plant sources, which requires further treatments to remove hemicellulose and lignin. In addition, increased_x000D_
demand for plant-based cellulose will ultimately lead to deforestation and other environmental concerns. The_x000D_
production of bacterial cellulose overcomes these problems, as bacteria can be grown in large quantities using_x000D_
simple carbon sources, including various types of industrial wastes and other by-products. Bacterial cellulose_x000D_
is currently used by the electronic, food and biomedical industries. Traditionally, bacterial cellulose has been_x000D_
produced by Gluconeoacetobacter xylinus, a bacteria which requires oxygen to grow. C.myxofaciens has been_x000D_
recently revealed to be a better candidate for cellulose production, as this bacteria can grow in both the_x000D_
presence and absence of oxygen, making it more suitable for growth in large-scale industrial fermentors. The_x000D_
aim of this proposal is to develop molecular genetics tools to manipulate this organism to better understand its_x000D_
regulation of cellulose biosynthesis, with the ultimate goal of developing safe, stable, cellulose-overproducing_x000D_
strains for industrial applications., agreement title english : Genetic enhancement of cellulose production by Cosenzeae myxofaciens, agreement title french : Genetic enhancement of cellulose production by Cosenzeae myxofaciens, agreement number : EGP, agreement value : 25000.0, agreement start date : 2018-03-07, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada