Reference number : GC-2017-Q1-00323, amendment number : , agreement type : G, recipient legal name : Sharif, Shayan (University of Guelph), recipient country : CA, recipient province : nan, recipient city : Ontario, recipient postal code : nan, program name english : Collaborative Research and Development Grants - Project, program name french : Subventions de recherche et développement coopérative - projet, program purpose english : The research proposed here focuses on in ovo supplementation of chick embryos with vitamins and probiotic bacteria. Newly hatched chicks are subject to various forms of stress that make them more susceptible to pathogens. Chicks can be made healthier by early interventions, such as by pre-hatch administration of nutrients and/or beneficial bacteria. More specifically, we intend to take a systematic approach and examine how these interventions can enhance the chicken's immune system health. Research into in ovo nutrition has demonstrated improvements in hatch weight and growth, digestive capacity, reduced post-hatch mortality and morbidity, and improved immune response. Probiotics have been shown to improve growth performance and feed efficiency, antibody response, and to limit food-borne pathogens. Given the potential of nutrients and probiotics to stimulate intestinal and immune system development, in ovo treatment could provide a natural barrier to pathogen colonization and allow accelerated intestinal and immune system development resulting in increased growth and health of birds. Given the routine in ovo use of various vaccines, anything else administered in ovo, in addition to having a positive effect on health and performance, must not interfere with vaccine efficacy., program purpose french : The research proposed here focuses on in ovo supplementation of chick embryos with vitamins and probiotic bacteria. Newly hatched chicks are subject to various forms of stress that make them more susceptible to pathogens. Chicks can be made healthier by early interventions, such as by pre-hatch administration of nutrients and/or beneficial bacteria. More specifically, we intend to take a systematic approach and examine how these interventions can enhance the chicken's immune system health. Research into in ovo nutrition has demonstrated improvements in hatch weight and growth, digestive capacity, reduced post-hatch mortality and morbidity, and improved immune response. Probiotics have been shown to improve growth performance and feed efficiency, antibody response, and to limit food-borne pathogens. Given the potential of nutrients and probiotics to stimulate intestinal and immune system development, in ovo treatment could provide a natural barrier to pathogen colonization and allow accelerated intestinal and immune system development resulting in increased growth and health of birds. Given the routine in ovo use of various vaccines, anything else administered in ovo, in addition to having a positive effect on health and performance, must not interfere with vaccine efficacy., agreement title english : The effect of in ovo delivery of nutrients and feed additives on the development of the immune system, agreement title french : The effect of in ovo delivery of nutrients and feed additives on the development of the immune system, agreement number : CRDPJ, agreement value : 30000.0, agreement start date : 2017-05-10, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year. (2017-2018 to 2019-2020), additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2019-2020), owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada