Reference number : GC-2017-Q1-00233, amendment number : , agreement type : G, recipient legal name : Fichtinger, Gabor (Queen’s University), recipient country : CA, recipient province : nan, recipient city : Ontario, recipient postal code : nan, program name english : Collaborative Health Research Projects, program name french : Projets de recherche concertée sur la santé, program purpose english : Breast cancer affects 1 in 8 women during their lives and is the second-leading cause of_x000D_
female cancer related deaths. The ideal treatment is breast-conservation surgery during its_x000D_
early stage to remove the cancer while conserving healthy parts of the breast._x000D_
When cancer cells are found on the edge of the resected tissue, the probability of recurrence_x000D_
is extremely high and the patient must have repeat surgery. On average, one out of every_x000D_
three or four women undergoing breast-conservation surgery needs at least one additional_x000D_
surgery due to tumor cells found on the resection margins. Repeat surgery leads to increased_x000D_
risk of postoperative complications, impaired cosmesis, delaying radiation therapy, increased_x000D_
psychological distress, increased costs, and risks of undergoing a second general_x000D_
anesthesia. Repeat surgery often leads to full mastectomy, which is a traumatic experience_x000D_
for a patient who expected a curative treatment with breast-conservation._x000D_
Through development of a novel real-time electromagnetic navigation system, we intend to_x000D_
improve the accuracy of breast cancer resection, which would lead to a significant reduction_x000D_
in the number of repeat surgeries, thus yielding major quality of life benefits for patients and_x000D_
much decreased costs for health care., program purpose french : Breast cancer affects 1 in 8 women during their lives and is the second-leading cause of_x000D_
female cancer related deaths. The ideal treatment is breast-conservation surgery during its_x000D_
early stage to remove the cancer while conserving healthy parts of the breast._x000D_
When cancer cells are found on the edge of the resected tissue, the probability of recurrence_x000D_
is extremely high and the patient must have repeat surgery. On average, one out of every_x000D_
three or four women undergoing breast-conservation surgery needs at least one additional_x000D_
surgery due to tumor cells found on the resection margins. Repeat surgery leads to increased_x000D_
risk of postoperative complications, impaired cosmesis, delaying radiation therapy, increased_x000D_
psychological distress, increased costs, and risks of undergoing a second general_x000D_
anesthesia. Repeat surgery often leads to full mastectomy, which is a traumatic experience_x000D_
for a patient who expected a curative treatment with breast-conservation._x000D_
Through development of a novel real-time electromagnetic navigation system, we intend to_x000D_
improve the accuracy of breast cancer resection, which would lead to a significant reduction_x000D_
in the number of repeat surgeries, thus yielding major quality of life benefits for patients and_x000D_
much decreased costs for health care., agreement title english : Real-time Breast Cancer Surgery Navigation, agreement title french : Real-time Breast Cancer Surgery Navigation, agreement number : CHRPJ, agreement value : 194419.0, agreement start date : 2017-04-25, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year. (2017-2018 to 2020-2021), additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2020-2021), owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada