Reference number : GC-2017-Q4-00575, amendment number : , agreement type : G, recipient legal name : Finlay, Warren (University of Alberta), recipient country : CA, recipient province : nan, recipient city : Alberta, recipient postal code : nan, program name english : Engage Plus Grants for universities, program name french : Subvention d'engagement partenarial Plus pour les universités, program purpose english : This project will continue work aimed at understanding how process parameters affect an existing technology developed by us for freeze-drying biological and medical solutions to produce powders. Freeze-dried bio-medical powders are used in pharmaceuticals as well as for food. The technology we will employ in this project is called atmospheric spray freeze drying (ASFD) and has the potential to be faster and more economical than current methods and to work for a wider variety of substances than allowed for by current methods. During our previous Engage grant, we improved the monitoring and process control of our AFSD equipment. In the proposed work, we will examine the effects of different process parameter variations on the attributes of the powders produced with AFSD. This work will aim towards optimization of process parameters to produce powders with given desired properties. Use of AFSD will be explored using pharmaceutical formulations of interest to the industry partner and comparison to conventional tray freeze-drying will be made. As part of the proposed research, we will examine the ability of AFSD to produce dried material with desired properties but with reduced processing time and cost compared to the other methods used by the industry partner. In addition, we wish to continue improving our understanding of how process parameters and their control affect the essential properties of atmospheric spray freeze dried material., program purpose french : This project will continue work aimed at understanding how process parameters affect an existing technology developed by us for freeze-drying biological and medical solutions to produce powders. Freeze-dried bio-medical powders are used in pharmaceuticals as well as for food. The technology we will employ in this project is called atmospheric spray freeze drying (ASFD) and has the potential to be faster and more economical than current methods and to work for a wider variety of substances than allowed for by current methods. During our previous Engage grant, we improved the monitoring and process control of our AFSD equipment. In the proposed work, we will examine the effects of different process parameter variations on the attributes of the powders produced with AFSD. This work will aim towards optimization of process parameters to produce powders with given desired properties. Use of AFSD will be explored using pharmaceutical formulations of interest to the industry partner and comparison to conventional tray freeze-drying will be made. As part of the proposed research, we will examine the ability of AFSD to produce dried material with desired properties but with reduced processing time and cost compared to the other methods used by the industry partner. In addition, we wish to continue improving our understanding of how process parameters and their control affect the essential properties of atmospheric spray freeze dried material., agreement title english : Improved powder production processes, agreement title french : Improved powder production processes, agreement number : EGP2, agreement value : 12500.0, agreement start date : 2018-03-07, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada