Reference number : GC-2017-Q1-00332, amendment number : , agreement type : G, recipient legal name : Goh, Cynthia (University of Toronto), recipient country : CA, recipient province : nan, recipient city : Ontario, recipient postal code : nan, program name english : Collaborative Research and Development Grants - Project, program name french : Subventions de recherche et développement coopérative - projet, program purpose english : Universal NanoSensor Technologies (UNS-Tech) develops and commercializes nanochip and microfluidic impedance detectors. UNS-Tech's microfluidic conductivity detector for ion chromatography rivals the most sensitive currently available on the market but at a significantly lower price point.  The nanochip is sensitive to material deposited on its surface at the sub monolayer level.  It is manufactured using silicon fabrication methods and is also cost-effective._x000D_
  In this CRD project, UNS-Tech will partner with Prof. Cynthia Goh to extend and demonstrate the capacities of these technologies. The microfluidic detector's performance will be modeled using an equivalent resistor - capacitor model, which will then be exploited to extend its performance to include dielectric constant (DC) detection. DC is a universal property of matter, in turn making this detector a universal detector like a refractive index detector used in chromatography, but at a much lower price point and potentially with higher sensitivity.  Also, in this project both the microfluidic and the nanochip detectors will be modified to enable them to function as sensors; i.e. they will be surface functionalized with molecular "recognition elements" that selectively bind to specific "targets", and the binding will be monitored using impedance spectroscopy._x000D_
  Applications of the new capabilities of both the microfluidic and nanochip technologies will be demonstrated, e.g. DC will be used to detect carbohydrates and polyethylene glycol and the sensors to detect crown ether/lead and biotin/avidin binding.  The results will be analyzed and the findings will be published in scientific journals. Working with a company partner will provide students with invaluable real world experience developing products and enhance their training as highly qualified personnel as they prepare to enter the Canadian work force. UNS-Tech - an Ontario-based company - will also benefit. Achieving successful demonstrations in a university setting and publishing the results would be critical benchmarks for UNS-Tech before moving onto product development, beta tests and new product lines.  This will require employing more Ontarians and will, in turn, benefit both Ontario and Canada._x000D_
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_x000D_, program purpose french : Universal NanoSensor Technologies (UNS-Tech) develops and commercializes nanochip and microfluidic impedance detectors. UNS-Tech's microfluidic conductivity detector for ion chromatography rivals the most sensitive currently available on the market but at a significantly lower price point.  The nanochip is sensitive to material deposited on its surface at the sub monolayer level.  It is manufactured using silicon fabrication methods and is also cost-effective._x000D_
  In this CRD project, UNS-Tech will partner with Prof. Cynthia Goh to extend and demonstrate the capacities of these technologies. The microfluidic detector's performance will be modeled using an equivalent resistor - capacitor model, which will then be exploited to extend its performance to include dielectric constant (DC) detection. DC is a universal property of matter, in turn making this detector a universal detector like a refractive index detector used in chromatography, but at a much lower price point and potentially with higher sensitivity.  Also, in this project both the microfluidic and the nanochip detectors will be modified to enable them to function as sensors; i.e. they will be surface functionalized with molecular "recognition elements" that selectively bind to specific "targets", and the binding will be monitored using impedance spectroscopy._x000D_
  Applications of the new capabilities of both the microfluidic and nanochip technologies will be demonstrated, e.g. DC will be used to detect carbohydrates and polyethylene glycol and the sensors to detect crown ether/lead and biotin/avidin binding.  The results will be analyzed and the findings will be published in scientific journals. Working with a company partner will provide students with invaluable real world experience developing products and enhance their training as highly qualified personnel as they prepare to enter the Canadian work force. UNS-Tech - an Ontario-based company - will also benefit. Achieving successful demonstrations in a university setting and publishing the results would be critical benchmarks for UNS-Tech before moving onto product development, beta tests and new product lines.  This will require employing more Ontarians and will, in turn, benefit both Ontario and Canada._x000D_
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_x000D_, agreement title english : Applications of impedometry using micro - and nano - electrodes, agreement title french : Applications of impedometry using micro - and nano - electrodes, agreement number : CRDPJ, agreement value : 360000.0, agreement start date : 2017-06-14, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year. (2017-2018 to 2022-2023), additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2022-2023), owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada