Reference number : GC-2017-Q4-00593, amendment number : , agreement type : G, recipient legal name : Fortier, Isabelle (Cégep de Lévis-Lauzon), recipient country : CA, recipient province : nan, recipient city : Quebec|Québec, recipient postal code : nan, program name english : Engage Grants for colleges, program name french : Subventions d'engagement partenarial pour les collèges, program purpose english : This project aims to assess the biological efficacy of Ginnalin A, a phenolic antioxidant compound extracted from red maples buds, in the treatment of inflammatory bowel disease using a murine model. TransBIOTech will first perform a standard pharmacokinetic analysis of Ginnalin A to establish compound bioavailability and proper dosage for the efficacy study. Using the DSS-induced colitis murine model, TransBIOTech will further establish the capability of Ginnalin A at reducing the model associated symptoms at the macroscopical, histological and biochemical levels., program purpose french : This project aims to assess the biological efficacy of Ginnalin A, a phenolic antioxidant compound extracted from red maples buds, in the treatment of inflammatory bowel disease using a murine model. TransBIOTech will first perform a standard pharmacokinetic analysis of Ginnalin A to establish compound bioavailability and proper dosage for the efficacy study. Using the DSS-induced colitis murine model, TransBIOTech will further establish the capability of Ginnalin A at reducing the model associated symptoms at the macroscopical, histological and biochemical levels., agreement title english : Efficiency of Ginnalin A in an inflammatory-induced colitis model, agreement title french : Efficiency of Ginnalin A in an inflammatory-induced colitis model, agreement number : CARD1, agreement value : 25000.0, agreement start date : 2018-03-07, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada