Reference number : GC-2017-Q4-00842, amendment number : , agreement type : G, recipient legal name : Jabaji, Suha (McGill University)|Jabaji, Suha (Université McGill), recipient country : CA, recipient province : nan, recipient city : Quebec|Québec, recipient postal code : nan, program name english : Engage Plus Grants for universities, program name french : Subvention d'engagement partenarial Plus pour les universités, program purpose english : The mission and vision of Mondias Naturals Inc (MNI) is to commercialize evidence-based botanical_x000D_
antimicrobial products for the residential, organic and commercial agricultural markets. Mondias has identified_x000D_
several herb extracts including CELEX07 that have antimicrobial activity. The previous NSERC-ENGAGE_x000D_
proposal (Application number 506182-16) was related to the needs of the industrial partner MNI to evaluate the_x000D_
use of plant extracts as biopesticides against economically important diseases of plant crops. The main focus of_x000D_
MNI was to obtain information on the minimum inhibitory concentration (MIC) of their botanical aqueous_x000D_
extracts (BE) prepared from plant roots of Chelidonium majus, (referred to as CELEX 07) against bacterial and_x000D_
fungal pathogens of tomato, tobacco and lettuce young plants, and compare CELEXT07 efficacy to existing_x000D_
botanical extracts products found on the market (Yarrow and Thyme flower extracts). The results confirmed_x000D_
that CELEXT07 applied as soil drench at the MIC 1% concentration showed growth stimulatory effect_x000D_
(increased plant height and weight) of tobacco and lettuce young plants compared to non-treated plants or_x000D_
plants treated with a combined dose of yarrow and CELEXT07. Armed with this knowledge, MNI is keen to_x000D_
address the following questions and objectives through NSERC Engage Plus: (1) What are the active_x000D_
metabolites of CELEXT07 prepared from root and leaf organs (2) Identify the signatory metabolite group_x000D_
responsible for growth stimulation of plants (e.g., phytohormones) and increased resistance (e.g., phenolics)_x000D_
against selective pathogens. (3) Carry out large-scale greenhouse experiments toevaluate the efficacy of_x000D_
CELEXT07 extracts from root vs. leaf for disease suppression of Botrytis cinerea and Xanthomonas_x000D_
campestris, the causal agents of grey mould and bacterial leaf spots on lettuce, respectively._x000D_
The execution of the above objectives will provide Mondias Naturals Inc. an independent assessment and_x000D_
scientific evidence on the active metabolite in the botanical extract CELEX07 as well as the biotechnological_x000D_
potential to develop a monotherapy-type line of formulations targeted for specific agricultural markets., program purpose french : The mission and vision of Mondias Naturals Inc (MNI) is to commercialize evidence-based botanical_x000D_
antimicrobial products for the residential, organic and commercial agricultural markets. Mondias has identified_x000D_
several herb extracts including CELEX07 that have antimicrobial activity. The previous NSERC-ENGAGE_x000D_
proposal (Application number 506182-16) was related to the needs of the industrial partner MNI to evaluate the_x000D_
use of plant extracts as biopesticides against economically important diseases of plant crops. The main focus of_x000D_
MNI was to obtain information on the minimum inhibitory concentration (MIC) of their botanical aqueous_x000D_
extracts (BE) prepared from plant roots of Chelidonium majus, (referred to as CELEX 07) against bacterial and_x000D_
fungal pathogens of tomato, tobacco and lettuce young plants, and compare CELEXT07 efficacy to existing_x000D_
botanical extracts products found on the market (Yarrow and Thyme flower extracts). The results confirmed_x000D_
that CELEXT07 applied as soil drench at the MIC 1% concentration showed growth stimulatory effect_x000D_
(increased plant height and weight) of tobacco and lettuce young plants compared to non-treated plants or_x000D_
plants treated with a combined dose of yarrow and CELEXT07. Armed with this knowledge, MNI is keen to_x000D_
address the following questions and objectives through NSERC Engage Plus: (1) What are the active_x000D_
metabolites of CELEXT07 prepared from root and leaf organs (2) Identify the signatory metabolite group_x000D_
responsible for growth stimulation of plants (e.g., phytohormones) and increased resistance (e.g., phenolics)_x000D_
against selective pathogens. (3) Carry out large-scale greenhouse experiments toevaluate the efficacy of_x000D_
CELEXT07 extracts from root vs. leaf for disease suppression of Botrytis cinerea and Xanthomonas_x000D_
campestris, the causal agents of grey mould and bacterial leaf spots on lettuce, respectively._x000D_
The execution of the above objectives will provide Mondias Naturals Inc. an independent assessment and_x000D_
scientific evidence on the active metabolite in the botanical extract CELEX07 as well as the biotechnological_x000D_
potential to develop a monotherapy-type line of formulations targeted for specific agricultural markets., agreement title english : Biochemical profiling and activity of the botanical extract CELEXT07, agreement title french : Biochemical profiling and activity of the botanical extract CELEXT07, agreement number : EGP2, agreement value : 12500.0, agreement start date : 2018-03-22, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year (2017-2018 to 2018-2019)., additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier (2017-2018 à 2018-2019)., owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada