Reference number : GC-2017-Q1-00286, amendment number : , agreement type : G, recipient legal name : Bouchard, Hugo (Université de Montréal), recipient country : CA, recipient province : nan, recipient city : Quebec|Québec, recipient postal code : nan, program name english : Collaborative Research and Development Grants - Project, program name french : Subventions de recherche et développement coopérative - projet, program purpose english : In this project, we will develop a new technique combining ultrasound and X-ray imaging to track anatomy in real time during radiotherapy treatments. The study will be mainly focused on applications to 4D lung radiotherapy where correlation models are required to overcome the loss of ultrasound information in the presence of tissue-air interfaces. This joint effort takes place in collaboration between academia and the industry. A prototype of ultrasound imaging probe will be combined to an existing technology based on X-ray imaging which allows tracking anatomy in real time. Specialized algorithms will be developed to enable the integration of the ultrasound technology to this type of image-guided radiotherapy. Advanced tools will be developed to evaluate the performance of these algorithms in the context of radiation dose delivery. A prototype of mannequin allowing simulating the human respiratory motion and a model of the treatment machine will be built to enable predicting dose distributions received by the mannequin. This tool will be used as a mean of evaluation for the absolute performance of the technique and enable the development of a predictive model on the precision of tumour tracking in a clinical environment._x000D_, program purpose french : In this project, we will develop a new technique combining ultrasound and X-ray imaging to track anatomy in real time during radiotherapy treatments. The study will be mainly focused on applications to 4D lung radiotherapy where correlation models are required to overcome the loss of ultrasound information in the presence of tissue-air interfaces. This joint effort takes place in collaboration between academia and the industry. A prototype of ultrasound imaging probe will be combined to an existing technology based on X-ray imaging which allows tracking anatomy in real time. Specialized algorithms will be developed to enable the integration of the ultrasound technology to this type of image-guided radiotherapy. Advanced tools will be developed to evaluate the performance of these algorithms in the context of radiation dose delivery. A prototype of mannequin allowing simulating the human respiratory motion and a model of the treatment machine will be built to enable predicting dose distributions received by the mannequin. This tool will be used as a mean of evaluation for the absolute performance of the technique and enable the development of a predictive model on the precision of tumour tracking in a clinical environment._x000D_, agreement title english : Performance of an ultrasound probe prototype for motion management in radiotherapy, agreement title french : Performance of an ultrasound probe prototype for motion management in radiotherapy, agreement number : CRDPJ, agreement value : 70700.0, agreement start date : 2017-06-14, agreement end date : nan, description english : nan, description french : nan, expected results english : nan, expected results french : nan, additional information english : Grant or Award spanning more than one fiscal year. (2017-2018 to 2020-2021), additional information french : Subvention ou bourse octroyée s'appliquant à plus d'un exercice financier. (2017-2018 à 2020-2021), owner organization : nserc-crsng, owner organization title : Natural Sciences and Engineering Research Council of Canada | Conseil de recherches en sciences naturelles et en génie du Canada