lymphadenectomy or lymph node dissection is the surgical removal of one or more groups of lymph nodes .

it is almost always performed as part of the surgical management of cancer .

in a regional lymph node dissection , some of the lymph nodes in the tumor area are removed ; in a radical lymph node dissection , most or all of the lymph nodes in the tumor area are removed .

lymphadenectomy

rcts and quasi - rcts that compared lymphadenectomy versus no lymphadenectomy in adult women diagnosed with endometrial cancer .
to evaluate the effectiveness and safety of lymphadenectomy for the management of endometrial cancer .
lymphadenectomy in the management of stage i malignant melanoma : a prospective randomized study .
[ lymphadenectomy : indications - - technic - - invasion - - documentation ] .
postoperative complications after pelvic lymphadenectomy for the surgical staging of endometrial cancer . - pubmed - ncbi
sentinel node biopsy with lymphadenectomy - karenzupko & associates , inc . karenzupko & associates , inc .
sentinel lymph node mapping with staging lymphadenectomy for patients with endometrial cancer increases the detection of metastasis .
to compare the performance of sentinel lymph node ( sln ) mapping with staging lymphadenectomy versus staging lymphadenectomy alone for the detection of metastasis and the use of adjuvant therapies in patients with endometrial cancer .
post lymphadenectomy complications and quality of life among breast cancer patients in brazil . - pubmed - ncbi
was to compare the effects of drains versus no drains in preventing lymphocyst formation following pelvic lymphadenectomy .
lymphadenectomy in the management of stage i malignant melanoma : a prospective randomized study . - pubmed - ncbi
[ lymphadenectomy : indications - - technic - - invasion - - documentation ] . - pubmed - ncbi
this review found no evidence that lymphadenectomy decreases risk of death or disease recurrence compared with no lymphadenectomy in women with presumed stage i disease . evidence on serious adverse events suggests that women who undergo lymphadenectomy are more likely to experience surgery - related systemic morbidity or lymphoedema / lymphocyst formation . currently , no rct evidence shows the impact of lymphadenectomy in women with higher - stage disease and in those at high risk of disease recurrence .
caldwell , w . l . : why retroperitoneal lymphadenectomy for testicular tumors ? sth . med . j .
zielinski m . technical pitfalls of transcervical extended mediastinal lymphadenectomy - - how to avoid them and to manage intraoperative complications .
sentinel lymph node mapping with staging lymphadenectomy for patients with endometrial cancer increases the detection of metastasis . - pubmed - ncbi
to assess whether pelvic lymphadenectomy at surgical staging for endometrial carcinoma is an independent risk factor for the occurrence of postoperative complications .
patients received a standardized cervical injection of indocyanine green , followed by sentinel lymph node mapping and pelvic lymphadenectomy with or without para - aortic lymphadenectomy . sentinel lymph nodes that were negative on hematoxylin - and - eosin staining of sections were ultrastaged by immunohistochemistry for cytokeratin .
shimoyama s , seto y , yasuda h , kaminishi m . wider indications for the local resection of gastric cancer by adjacent lymphadenectomy .
the performance of sln mapping with staging lymphadenectomy increased the detection of lymph node metastasis and was associated with more use of adjuvant therapies .
to assess the effects of retroperitoneal drainage versus no drainage after pelvic lymphadenectomy on lymphocyst formation and related morbidities in women with gynaecological cancer .
zielinski m . transcervical extended mediastinal lymphadenectomy : results of staging in two hundred fifty - six patients with non - small cell lung cancer .
a comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging ( fires trial ) : a multicentre , prospective , cohort study .
a comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging ( fires trial ) : a multicentre , prospective , cohort study .
castro , j . r . : lymphadenectomy and radiation therapy in malignant tumors of the testicle other than pure seminoma . cancer ( philad . )
a recent trend for less invasive surgery has increased consideration for a minimized scope of lymphadenectomy for submucosal cancer ; however , feasibility criteria have not been precisely established .
a comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging ( fires trial ) : a multicentre , prospective , cohort study . - pubmed - ncbi
all patients with apparent early - stage endometrial cancer ( n = 780 ) who underwent robotic - assisted hysterectomy with pelvic±aortic lymphadenectomy from july - 2006 to june - 2013 were compared [ pelvic±aortic lymphadenectomy ( n = 661 ) versus sln - mapped cases with pelvic±aortic lymphadenectomy ( n = 119 ) ] . isosulfan - blue and indocyanine - green with near - infrared imaging were used for sln mapping . clinico - pathological data , figo stage , gog risk category , and adjuvant therapies were compared .
hata e , haykawa k , miyamoto h , et al . rationale for extended lymphadenectomy for lung cancer . theor surg . 1990 . 5 : 19 - 25 .
zielinski m , hauer l , hauer j , nabialek t , szlubowski a , pankowski j . non - small - cell lung cancer restaging with transcervical extended mediastinal lymphadenectomy .
kuzdzal j , zielinski m , papla b , narski m , szlubowski a , hauer l , et al . effect of bilateral mediastinal lymphadenectomy on short - term pulmonary function .
sentinel lymph nodes identified with indocyanine green have a high degree of diagnostic accuracy in detecting endometrial cancer metastases and can safely replace lymphadenectomy in the staging of endometrial cancer . sentinel lymph node biopsy will not identify metastases in 3 % of patients with node - positive disease , but has the potential to expose fewer patients to the morbidity of a complete lymphadenectomy .
sentinel lymph node mapping with complete pelvic lymphadenectomy was performed in 340 patients , including para - aortic lymphadenectomy in 196 patients ( 58 % ) . among these patients , 293 ( 86 % ) had successful mapping of at least 1 sentinel lymph node . overall , 41 patients ( 12 % ) had positive nodes , including 36 with ≥ 1 mapped sentinel lymph node .
the investigators concluded : “sentinel lymph nodes identified with indocyanine green have a high degree of diagnostic accuracy in detecting endometrial cancer metastases and can safely replace lymphadenectomy in the staging of endometrial cancer . sentinel lymph node biopsy will not identify metastases in 3 % of patients with node - positive disease , but has the potential to expose fewer patients to the morbidity of a complete lymphadenectomy . ”
shimoyama s , joujima y , yasuda h , oohara t , kaminishi m . prospectively performed modified d1 lymphadenectomy for clinically diagnosed mucosal , node negative gastric cancer : our findings over the past decade .
two review authors independently extracted data and assessed risk of bias . hazard ratios ( hrs ) for overall and progression - free survival and risk ratios ( rrs ) comparing adverse events in women who received lymphadenectomy versus those with no lymphadenectomy were pooled in random - effects meta - analyses . we assessed the quality of the evidence using the grade ( grades of recommendation , assessment , development and evaluation ) approach .
kuzdzal j , zielinski m , papla b , urbanik a , wojciechowski w , narski m , et al . the transcervical extended mediastinal lymphadenectomy versus cervical mediastinoscopy in non - small cell lung cancer staging .
placement of retroperitoneal tube drains has no benefit in the prevention of lymphocyst formation after pelvic lymphadenectomy in women with gynaecological malignancies . when the pelvic peritoneum is left open , the tube drain placement is associated with a higher
complete mediastinal lymphadenectomy will continue to be performed in medical centers demanding the most comprehensive information . this is justified by previous data demonstrating that the dissection can be performed with minimal time and no increase in morbidity and mortality .
walsh , p . c . , kaufman , j . j . , coulson , w . f . , goodwin , w . e . : retro - peritoneal lymphadenectomy for testicular tumors . j . amer . med . ass .
stanford has been a leading center in advancing the use of laparoscopic lymphadenectomy since the early 1990s . doctors at the stanford cancer center have been among the first to use the procedure in prostate cancer , endometrial cancer , and other genitourinary cancers .
this knowledge helps doctors understand how advanced the cancer is , and thus how to treat it . although lymph nodes can be biopsied or removed during a surgical procedure , it is now often possible to use a less invasive approach called a laparoscopic lymphadenectomy .
laparoscopic lymphadenectomy can provide results equivalent to surgical biopsies or lymph node removal and , although it is carried out under general anesthesia , it is less invasive than surgery so your hospital stay will be shorter and you will recover much faster and with less pain .
leschber g , holinka g , linder a . video - assisted mediastinoscopic lymphadenectomy ( vamla ) - - a method for systematic mediastinal lymphnode dissection . eur j cardiothorac surg . 2003 aug . 24 ( 2 ) : 192 - 5 . [ medline ] .
published in issue 6 , 2014 . pelvic lymphadenectomy is associated with significant complications including lymphocyst formation and related morbidities . retroperitoneal drainage using suction drains has been recommended as a method to prevent such complications . however , findings from recent studies have challenged this policy .
hürtgen m , friedel g , toomes h , fritz p . radical video - assisted mediastinoscopic lymphadenectomy ( vamla ) - - technique and first results . eur j cardiothorac surg . 2002 feb . 21 ( 2 ) : 348 - 51 . [ medline ] .
nicholson , t . c . , wash , p . c . , ratner , m . b . : lymphadenectomy combined with preoperative and postoperative cobalt 60 teletherapy in the management of embryonal carcinoma and teratocarcinoma of the testis . j . urol . ( baltimore )
during a laparoscopic lymphadenectomy the surgeon makes a small incision in the lower abdomen to reach the lymph nodes . a tiny tube with a light and a camera ( i . e . , a laparoscope ) is inserted into the incision and directed to the lymph nodes .
johnson d . e . ( 1977 ) retroperitoneal lymphadenectomy : indications , complications and expectations . in : grundmann e . , vahlensieck w . ( eds ) tumors of the male genital system . recent results in cancer research , vol 60 . springer , berlin , heidelberg
in the fires prospective cohort study reported in the lancet oncology , emma c . rossi , md , of the university of north carolina , chapel hill , and colleagues found that sentinel lymph node mapping was highly accurate in detecting metastases compared with complete lymphadenectomy in women with endometrial cancer .
charoenkwan k , kietpeerakool c . retroperitoneal drainage versus no drainage after pelvic lymphadenectomy for the prevention of lymphocyst formation in women with gynaecological malignancies . cochrane database of systematic reviews 2017 , issue 6 . art . no . : cd007387 . doi : 10 . 1002 / 14651858 . cd007387 . pub4
a mediastinal lymphadenectomy may be performed to achieve complete staging ( possibly to make postoperative treatment decisions ) , better locoregional control , and improved overall survival . arguments against the procedure include increased operating time , possible increased morbidity , and lack of conclusive evidence to support an increased survival from the procedure .
yoo dg , kim yh , kim dk , kim hr , park si . clinical feasibility and surgical benefits of video - assisted mediastinoscopic lymphadenectomy in the treatment of resectable lung cancer . eur j cardiothorac surg . 2011 dec . 40 ( 6 ) : 1483 - 6 . [ medline ] .
sentinel - lymph - node mapping has been advocated as an alternative staging technique for endometrial cancer . the aim of this study was to measure the sensitivity and negative predictive value of sentinel - lymph - node mapping compared with the gold standard of complete lymphadenectomy in detecting metastatic disease for endometrial cancer .
) that compared the effect of retroperitoneal drainage versus no drainage after pelvic lymphadenectomy in women with gynaecological cancer . retroperitoneal drainage was defined as placement of passive or active suction drains in pelvic retroperitoneal spaces . no drainage was defined as no placement of passive or active suction drains in pelvic retroperitoneal spaces .
mediastinal lymphadenectomy is indicated for t1 - 3 n0 - 1 resectable nsclc . patients should be without evidence of mediastinal lymph node involvement as assessed by preoperative imaging ( ct , pet , or both ) and sampling by means of mediastinoscopy , a chamberlain procedure , endoscopic ultrasonography , or a transbronchial technique .
maier , j . g . , buskirk , k . e . , van sulak , m . h . , perry , r . h . , schomber , d . t . : an evaluation of lymphadenectomy in the treatment of malignant testicular germ cell neoplasms . j . urol . ( baltimore )
call s , obiols c , rami - porta r , trujillo - reyes jc , iglesias m , saumench r , et al . video - assisted mediastinoscopic lymphadenectomy for staging non - small cell lung cancer . ann thorac surg . 2016 apr . 101 ( 4 ) : 1326 - 33 . [ medline ] .
witte b , messerschmidt a , hillebrand h , gross s , wolf m , kriegel e , et al . combined videothoracoscopic and videomediastinoscopic approach improves radicality of minimally invasive mediastinal lymphadenectomy for early stage lung carcinoma . eur j cardiothorac surg . 2009 feb . 35 ( 2 ) : 343 - 7 . [ medline ] .
when submucosal cancer is evaluated as ct1cn0 , a virtually sufficient minimized scope of lymphadenectomy is a d1 dissection for that within the cutoff diameter and a modified d2 dissection for that exceeding the cutoff diameter . these two types of dissection can even cover the infrequently observed node - positive stations and can realize no residual disease at surgery .
izbicki jr , passlick b , pantel k , pichlmeier u , hosch sb , karg o , et al . effectiveness of radical systematic mediastinal lymphadenectomy in patients with resectable non - small cell lung cancer : results of a prospective randomized trial . ann surg . 1998 jan . 227 ( 1 ) : 138 - 44 . [ medline ] .
darling ge , allen ms , decker pa , ballman k , malthaner ra , inculet ri , et al . randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with n0 or n1 ( less than hilar ) non - small cell carcinoma : results of the american college of surgery oncology group z0030 trial .
wang x , yan s , phan k , yan td , zhang l , yang y , et al . mediastinal lymphadenectomy fulfilling nccn criteria may improve the outcome of clinical n0 - 1 and pathological n2 non - small cell lung cancer . j thorac dis . 2016 mar . 8 ( 3 ) : 342 - 9 . [ medline ] . [ full text ] .
patients receive radiolabeled technetium tc 99m sulfur colloid injected around the tumor 6 hours prior to or after induction of anesthesia right before surgery . patients then undergo radical hysterectomy and complete pelvic and low para - aortic lymphadenectomy . intraoperatively , patients undergo lymphatic mapping and sentinel lymph node identification using isosulfan blue or methylene blue injected at 4 locations in the cervix and a hand - held gamma counter .
a critical review of published literature on mediastinal lymphadenectomy requires an understanding of the described operative technique . sampling refers to the technique of removing easily found and obviously abnormal mediastinal lymph nodes . systematic sampling refers to the routine biopsy of lymph nodes at levels or stations as specified by the authors . complete mediastinal lymph node dissection refers to the routine complete removal of all mediastinal tissue as described by the authors .
dykhuizer , r . f . , george , f . w . , iii , kirohara , s . , ratner , m . , sargent , c . r . , varney , j . k . : the use of cobalt 60 telecurietherapy or x - ray therapy with and without lymphadenectomy in the treatment of testis germinal tumors ; a 20 - year comparison study . j . urol . ( baltimore )
the surgeon documented that she performed a partial mastectomy , sentinel node mapping , sentinel node biopsy and a complete lymphadenectomy . our question is directed at the sentinel node biopsy only as we are receiving denials for this procedure . we are reporting cpt code 38525 with 19302 and are receiving a denial as inclusive . we are not sure what modifier to use as the modifier 59 submitted on appeal is not bypassing our payor’s edit .
this is an often asked question . while the sentinel node biopsy is separately reportable with a partial mastectomy , the work is considered inclusive to the lymphadenectomy performed on the same day and is not separately reportable . the denial as inclusive to cpt code 19302 is correct . perform a write off on the account for cpt code 38792 as a coding error adjustment for tracking purposes . use this example as part of your compliance review .
the nci dictionary of cancer terms features 8 , 287 terms related to cancer and medicine .
we offer a widget that you can add to your website to let users look up cancer - related terms . get nci’s dictionary of cancer terms widget .
the search textbox has an autosuggest feature . when you enter three or more characters , a list of up to 10 suggestions will popup under the textbox . use the arrow keys to move through the suggestions . to select a suggestion , hit the enter key . using the escape key closes the listbox and puts you back at the textbox . the radio buttons allow you to toggle between having all search items start with or contain the text you entered in the search box .
a surgical procedure to remove most or all of the lymph nodes that drain lymph from the area around a tumor . the lymph nodes are then examined under a microscope to see if cancer cells have spread to them .
the nci dictionary of cancer terms features 8 , 239 terms related to cancer and medicine .
national medical specialty societies as well as organizations representing other members of the clinical care team are working with the abim foundation to help providers , patients and other health care stakeholders think and talk about overuse of health care resources in the united states .
specialty society partners are also expected to review and update their list on an annual basis to ensure that it continues to reflect the best evidence as well as review and update the list as needed upon publication of new evidence that contradicts one or more society recommendations .
by partnering in the choosing wisely campaign , aapm & r hopes that patients will initiate discussions with their physicians .
as the global leader in clinical chest medicine , the american college of chest physicians ( chest ) represents more than 18 , 700 members who provide patient care in the areas of pulmonary , critical care , and sleep medicine in the united states and more than 100 countries worldwide . from cutting - edge medical research in the journal chest ; evidence - based guidelines in antithrombotic therapy , lung cancer , and chronic cough ; to innovative clinical education delivered through the chest annual meeting , simulation education program , and board review courses , chest strives to fulfill its mission – to promote the prevention , diagnosis , and treatment of chest diseases through education , communication , and research .
the american college of obstetricians and gynecologists ( the college ) , representing over 56 , 000 physicians and partners in women’s health , is proud to partner with the choosing wisely ® campaign . the college promotes quality , safety and efficiency in the delivery of women’s health care services . the college believes that the efforts of the choosing wisely campaign will directly contribute to these goals . recommendations that are based on specific medical evidence should be discussed between physicians and their patients to help make wise decisions about appropriate care . these efforts are particularly important since women are the primary decision makers for themselves and their families with regard to health care .
the american epilepsy society believes in the importance of engaging patients and providers in conversations that empower patients and lead to improved care . people living with epilepsy , a complex spectrum of disorders , connect with our health system in many different ways and across multiple areas . assuring not only that appropriate tests , procedures and treatments are offered but also that unnecessary interventions are avoided is critical to those living with one of the most common neurological disorders .
in support of our 16 , 000 members who are committed to high - quality patient care , the american gastroenterological association ( aga ) is pleased to join the abim foundation and many other esteemed medical societies in the choosing wisely ® campaign . by developing clinical guidelines and quality measures , the aga ensures that the patient care decisions made by gastroenterologists are guided by scientific evidence . through the choosing wisely campaign , we hope to further increase physician and patient understanding of which tests and procedures will benefit which patients , and in doing so minimize the misuse of costly screening and diagnostic tests .
amda — the society for post - acute and long - term care medicine ( amda ) is proud to be a partner in the choosing wisely® campaign . amda , the national professional association of medical directors , attending physicians , and other professionals practicing long term care medicine , is dedicated to excellence in patient care . amda provides education , advocacy , information , and professional development to enable its 5 , 000 - plus members to deliver quality long term care .
the american psychiatric association ( apa ) , founded in 1844 , is the world’s largest psychiatric organization . it is a medical specialty society representing more than 33 , 000 psychiatric physicians from the united states and around the world . its member physicians work together to ensure humane care and effective treatment for all persons with mental disorders , including intellectual disabilities and substance use disorders . apa is the voice and conscience of modern psychiatry . participating in the choosing wisely ® campaign furthers apa’s mission to promote the highest quality care for individuals with mental disorders ( including intellectual disabilities and substance use disorders ) and their families .
the american society for apheresis ( asfa ) is an organization of physicians , scientists , and allied health professionals whose mission is to advance apheresis medicine for patients , donors and practitioners through education , evidence - based practice , research and advocacy . asfa represents a broad range of professionals involved in : donor apheresis , apheresis in transplantation , and therapeutic apheresis . asfa is proud to join the choosing wisely campaign and advance efforts to reduce waste and overuse in health care .
the american society for reproductive medicine ( asrm ) , founded in 1944 , is the oldest and largest society devoted to reproductive medicine in the world with approximately 8000 members . asrm is proud to partner with the choosing wisely ® campaign and its focus on encouraging a dialog between health care providers and patients . as the leading multidisciplinary organization dedicated to the advancement of the art , science , and practice of reproductive medicine worldwide , asrm attempts to educate both the public and its members about the best practices in the field and views this campaign as consistent with its goals . the society views this campaign as complementary to its development of evidence - based practice guidelines for its members and the translation of these guidelines into patient information materials for the public .
the american thoracic society’s mission is to improve health worldwide by advancing research , clinical care , and public health in respiratory disease , critical illness , and sleep disorders . founded in 1905 to combat tuberculosis , the ats is the world’s oldest respiratory society . while the scope of the society’s activities have expanded greatly , its founding philosophy–that disease is vanquished faster when knowledge is shared–remains a touchstone for its programs and people , including 15 , 000 members . for more information , please visit urltoken .
the american urogynecologic society ( augs ) is proud to partner with the choosing wisely campaign . founded in 1979 , augs is the premier non - profit organization representing more than 1 , 800 members including practicing physicians , nurse practitioners , physical therapists , nurses and health care professionals , as well as researchers from many disciplines , all dedicated to treating female pelvic floor disorders .
as the leader in female pelvic medicine and reconstructive surgery , augs promotes the highest quality patient care through excellence in education , research and advocacy . participation in choosing wisely® complements augs’ commitment to quality improvement , and improving patient care practices and outcomes .
the heart rhythm society ( hrs ) is the international leader in science , education and advocacy for cardiac arrhythmia professionals and patients , and the primary information resource on heart rhythm disorders . its mission is to improve the care of patients by promoting research , education and optimal health care policies and standards . representing more than 5 , 800 heart rhythm professionals in more than 70 countries around the world , hrs is pleased to partner in the choosing wisely ® campaign to help ensure that people living with heart rhythm disorders receive optimal care and improved quality of life . the society also is a leader of the “ apples and oranges ” sudden cardiac arrest awareness campaign aimed at sharing the differences between sca and heart attack and the “ afib feels like ” awareness campaign aimed at helping people understand the symptoms , risks , and treatment options for atrial fibrillation , the most common heart rhythm disorder . for more information , follow hrs on twitter , facebook , linkedin , or the society’s blog , ep insights .
hivma is pleased to partner with the choosing wisely® campaign to raise awareness of inappropriate , wasteful clinical actions that harm patients and lead to wasteful health costs . consistent with the mission of choosing wisely® , hivma is committed to evidence - based medicine and continually develops and updates clinical practice guidelines that inform the use of high - quality , truly necessary medicine .
founded in 2001 , the society for the advancement of blood management ( sabm ) was started by a group of dedicated volunteers who saw a need for a new way of thinking . the sabm founders realized that blood management ought to be the standard of care , and that blood transfusion should be viewed as the alternative . today , sabm is recognized as a key educational resource for patient blood management . sabm is grounded in scientific validation , evidence - based practices and focused on promoting the patients’ best interest through effective and optimal blood management .
sabm defines its mission as the improvement of health outcomes by advancing comprehensive patient blood management practices , promoting innovative research , and providing quality professional and public education .
given our mission and message , sabm is truly honored and proud to partner with the choosing wisely® campaign .
as a leading voice in infection prevention and antibiotic stewardship , the society for healthcare epidemiology of america ( shea ) strongly supports the goals of the choosing wisely® campaign and is a proud to partner in helping raise awareness of inappropriate clinical actions that can harm patients and increase the cost of care . shea is a professional society representing physicians and other healthcare professionals around the world with expertise in healthcare epidemiology , infection prevention , and antibiotic stewardship . the society is on the forefront of the education , research , and guideline development for the appropriate and safe use of antibiotics , as well as clinical practices that reduce healthcare - associated infections , optimize patient safety , control costs , and reduce resistance to antimicrobials .
choosing wisely® is an initiative of the abim foundation . © 2018 . all rights reserved .
html public
- / / w3c / / dtd xhtml 1 . 0 strict / / en
urltoken
notice : users may be experiencing issues with displaying some pages on stanfordhealthcare . org . we are working closely with our technical teams to resolve the issue as quickly as possible . thank you for your patience .
access your health information from any device with myhealth . you can message your clinic , view lab results , schedule an appointment , and pay your bill .
the myhealth mobile app puts all your health information at your fingertips and makes managing your health care simple and quick . available for iphone and android .
when investigating pelvic cancers ( such as prostate , testicular , cervical , and uterine cancers ) it is important to know whether the disease has spread to the lymph nodes in the region .
the doctor navigates and inspects the region on a tv - like monitor that receives images from the camera , and can biopsy or remove the lymph nodes with a cutting instrument and tissue retrieval apparatus that is also part of the laparoscope .
in addition , the laparoscope images are magnified when they appear on the monitor , allowing your doctor to see even greater tissue detail than would be available during traditional surgery .
like all surgeries , the success of laparoscopic surgery is related to doctor ' s experience with the technique . with well over a decade of experience , you can be assured that the stanford cancer center provides the reliable , quality care that is essential when you are facing cancer .
if a woman has symptoms of endometrial cancer , her doctor will examine her and possibly order blood and urine tests .
pelvic exam and pap smears , which look for cervical cancer , can also find a small number of endometrial cancers before symptoms develop .
transvaginal ultrasound , in which the doctor inserts a wand - like instrument into the vagina . the instrument aims high - frequency sound waves at the uterus . the pattern of the echoes they produce creates a picture . saltwater can be placed into the uterus through the cervix before the ultrasound test to give a clearer picture . this is called a sonohystogram . if the endometrium looks too thick or irregular , the doctor can perform an endometrial biopsy in the office or a dilation and curettage ( d & c ) in the operating room .
the definitive test is a biopsy ( taking and testing a tissue sample from the uterus ) . if a biopsy confirms the diagnosis , the doctor will order imaging tests such as a ct scan or mri ; blood tests for ca - 125 , a marker seen both with ovarian and endometrial cancer ; and a colonoscopy . the doctor may also order exploratory surgery ( opening the abdomen ) to determine how far the disease has spread .
if the cancer has spread beyond the uterus , then after surgery the patient is given radiation , often in combination with chemotherapy , to wipe out the remaining cancer cells . some doctors also recommend radiation when the tumor is large but has not spread beyond the uterus .
patients in remission need checkups every few months for several years . if cancer comes back , it usually happens within three years . caught early , cancer that comes back may be cured with aggressive radiation , chemotherapy , or more surgery .
to help cope with the emotional difficulties of having uterine cancer , patients might consider joining a support group . counseling is especially helpful for pre - menopausal women who become depressed after a hysterectomy .
lebovic , d . ; gordon , j . ; taylor , r . ;
reproductive endocrinology & infertility .
scrubb hill press , 2005 .
melanoma is a type of skin cancer . when it spreads to other places in your body , it ' s called metastatic , or advanced . you may also hear your doctor refer to it as stage iv melanoma .
although in most cases it can ' t be cured , treatments and support can help you live longer and better . doctors have new therapies that have greatly increased survival rates . and researchers are working to find new medications that can do even more .
remember : you still have control over the decisions you make about your treatment and your life . it ' s important to have people you can talk to about your plans , your fears , and your feelings . so find support and learn about your treatment options . that will help you make the most of your life .
in most cases , melanoma is caused by exposure to ultraviolet ( uv ) radiation from the sun or tanning beds . it damages the dna of your skin cells , and they start to grow out of control .
you can get the disease on parts of your body that don ' t get sunlight , though , like the palms of your hands and the retinas of your eyes .
if you haven’t already been diagnosed with melanoma , your doctor will do a skin exam . if he thinks you may have skin cancer , you ' ll need a biopsy to find out .
a doctor will look at the growth under a microscope to see how thick it is . usually , a thicker tumor means the cancer is more serious .
if you ' ve been diagnosed with melanoma , you may also have a blood test and an imaging test to see if it has spread to other areas .
chest x - ray . this uses radiation in low doses to make pictures of the inside of your body .
ct scan ( computerized tomography ) . it uses powerful x - rays so your doctor can get a detailed look at what ' s going on inside you .
mri ( magnetic resonance imaging ) . it uses powerful magnets and radio waves to make pictures of organs and structures inside your body . it helps show blood flow and can help locate cancer growths .
pet scan . this test uses radioactive material to look for signs of cancer .
the doctor will also check to see if your lymph nodes are enlarged . lymph nodes are bean - sized glands under the skin in your neck , underarms , and groin . the doctor uses a thin needle to remove a sample of cells . this is called a fine - needle aspiration biopsy .
the doctor may also do a lymph node biopsy . this removes the lymph nodes most likely to have cancer cells . in this test , the doctor injects a dye into the area where the potential cancer was . it spreads to the nearest lymph nodes , which are removed and tested . if these lymph nodes , called sentinel nodes , don ' t have cancer , then it ' s likely the cancer hasn ' t spread .
the results of these tests help the doctor determine the stage of your cancer and how widespread it is .
you and your doctor will decide on the best treatment plan once you know that information .
although metastatic melanoma is not easy to treat , you do have options . choosing what ' s right for you will depend on where and how big the cancer is , what your health is like , and what your wishes are . since most cases of metastatic melanoma can ' t be cured , the goals of treatment are to :
treatment used to be mainly radiation and chemotherapy . now there are newer drugs available that can work better , studies show . your treatment may include :
surgery . your doctor may remove tumors or lymph glands . although surgery alone probably won ' t cure the cancer , it can help you live longer and have fewer symptoms . your doctor will likely also use one or more other treatments .
radiation and chemotherapy . these can help some people , depending on the size and location of the cancer .
immunotherapy . these drugs boost your immune system so it can better attack the cancer . you get immunotherapy through an iv or a shot in high doses . it can have serious side effects , but it can also shrink metastatic melanomas and help some people live longer . these drugs include :
interferon - alpha and interleukin - 2 : these older drugs can help some people live longer .
ipilimumab ( yervoy ) : there are two uses for this drug . it can be given to individuals who have had surgery to remove melanoma in order to prevent the melanoma from coming back . it can also be used for late - stage melanoma that cannot be removed by surgery . but the drug doesn ' t work for everyone , and it can have serious , even life - threatening , side effects .
nivolumab ( opdivo ) : it works by inhibiting the pd - 1 protein on cells , which blocks the body’s immune system from attacking melanoma tumors . it ' s been shown to increase overall survival .
pembrolizumab ( keytruda ) : in people with advanced melanoma who have already been treated with yervoy , keytruda may shrink tumors in some . you take it as an iv infusion every 3 weeks .
researchers are studying many other drugs that spur the immune system to fight melanoma . because metastatic melanoma is so hard to treat , you may want to ask your doctor about taking part in a clinical trial , which uses a treatment that ' s still under research .
targeted therapy . this kind of treatment aims to kill cancer cells without harming healthy ones . they may work for people who have certain changes in genes . because these treatments target the tumors , they may cause fewer side effects than chemotherapy or radiation .
some drugs attack a gene called braf . about half the people who have melanoma have changes in this gene , which helps cancer cells grow . if you have a tumor with braf , these drugs may shrink it and extend your life . they include :
other drugs block an enzyme called mek . this enzyme is often overactive in some cancers . these drugs , working in combination with a braf inhibitor to attack cancer cells , seem to shrink tumors for a longer period of time :
hearing that your cancer has spread is scary , but a lot of research is underway to find new treatments . and there are treatments available to try to stop the disease from spreading , so you can live longer .
it ' s important to have support and to talk about your fears and feelings , too . your doctor can help you find a cancer support group .
if you lose your appetite , eat small amounts of food every 2 to 3 hours instead of bigger meals . a dietitian can give you other tips on nutrition and eating during your cancer treatment . ask your doctor for a referral .
exercise can help you feel better overall and fight fatigue . but listen to your body , and balance rest and activity .
get the kind of emotional support that ' s right for you . it could be from family , friends , your cancer support group , or a religious group .
although stage iv melanoma is hard to treat , each case is different , and some people will respond very well to treatment . talk to your doctor about all your options , and find out more about clinical trials to see if one is right for you .
the melanoma research foundation has an online library of free support services , including an online patient community and a phone buddy program . and for more information on metastatic melanoma , go to the web site of the skin cancer foundation .
if you are interested in more advanced reading on this topic , we’ve made content from our health professional site , medscape , available to you on webmd .
american cancer society :
melanoma skin cancer overview ,
treatment of melanoma sin cancer by stage , ”
targeted therapy for melanoma skin cancer .
fda :
fda approves yervoy to reduce the risk of melanoma returning after surgery ,
fda approves cotellic as part of combination treatment for advanced melanoma .
national cancer institute :
what you need to know about melanoma and other skin cancers .
medscape : “some melanoma patients living for up to 10 years after ipilimumab . ”
uptodate :
melanoma treatment ; advanced or metastatic melanoma ( beyond the basics ) .
html public
- / / w3c / / dtd xhtml 1 . 0 transitional / / en
urltoken
warning : the ncbi web site requires javascript to function . more . . .
cochrane database syst rev . 2015 sep 21 ; ( 9 ) : cd007585 . doi : 10 . 1002 / 14651858 . cd007585 . pub3 .
obstetrics and gynaecology , gloucestershire hospitals nhs foundation trust , great western road , gloucester , uk , gl1 3nn .
we searched the cochrane central register of controlled trials ( central ) , the cochrane gynaecological cancer review group trials register , medline and embase to june 2009 for the original review and extended the search to june 2015 for this version of the review . we also searched registers of clinical trials , abstracts of scientific meetings and reference lists of included studies , and we contacted experts in the field .
please confirm that you would like to log out of medscape . if you log out , you will be required to enter your username and password the next time you visit . log out cancel
author : r james koness , md , facs ; chief editor : erik d schraga , md more . . .
the classification of regional lymph node stations for lung cancer staging reported by mountain and dresler in 1997 describes the anatomic landmarks for 14 levels of intrapulmonary , hilar , and mediastinal lymph nodes stations . [ 5 ] tnm classification for lung cancer classifies lymph node stations into six zones , as follows :
n3 lymph nodes are contralateral mediastinal , ipsilateral scalene , or supraclavicular . among the primary tumors that had only a single involved n2 station , the most common site of lymph node metastases was level 4r for right - upper - lobe tumors , levels 5 / 6 for left - upper - lobe tumors , and level 7 for middle - and lower - lobe tumors . [ 6 ]
four published randomized trials compared mediastinal lymph node dissection and mediastinal lymph node sampling . [ 7 , 8 , 9 , 10 ] a meta - analysis of the first three trials reported a survival advantage for stages i , ii , and iiia , and a fixed - effects model by the same group reported that mediastinal lymph node dissection reduced the risk of death . [ 11 , 12 ]
call et al assessed the results of vamla for staging nsclc in 160 cases , 138 of which involved clinical n0 - 1 cancers . [ 13 ] they found vamla to be highly accurate , with a sensitivity of 0 . 96 ( 95 % confidence interval [ ci ] , 0 . 81 - 99 . 3 ) , a specificity of 1 ( 95 % ci , 0 . 97 - 1 ) , a positive predictive value of 1 ( 95 % ci , 0 . 87 - 1 ) , a negative predictive value of 0 . 99 ( 95 % ci , 0 . 95 - 0 . 99 ) , and a diagnostic accuracy of 0 . 99 ( 95 % ci , 0 . 96 - 0 . 99 ) . complications developed in 5 . 9 % of patients .
cahan wg , watson wl , pool jl . radical pneumonectomy . j thorac surg . 1951 nov . 22 ( 5 ) : 449 - 73 . [ medline ] .
little ag , rusch vw , bonner ja , gaspar le , green mr , webb wr , et al . patterns of surgical care of lung cancer patients . ann thorac surg . 2005 dec . 80 ( 6 ) : 2051 - 6 ; discussion 2056 . [ medline ] .
ginsberg rj . resection of non - small cell lung cancer : how much and by what route . chest . 1997 oct . 112 ( 4 suppl ) : 203s - 205s . [ medline ] .
mountain cf , dresler cm . regional lymph node classification for lung cancer staging . chest . 1997 jun . 111 ( 6 ) : 1718 - 23 . [ medline ] .
rusch vw , crowley j , giroux dj , goldstraw p , im jg , tsuboi m , et al . the iaslc lung cancer staging project : proposals for the revision of the n descriptors in the forthcoming seventh edition of the tnm classification for lung cancer . j thorac oncol . 2007 jul . 2 ( 7 ) : 603 - 12 . [ medline ] .
sugi k , nawata k , fujita n , ueda k , tanaka t , matsuoka t , et al . systematic lymph node dissection for clinically diagnosed peripheral non - small - cell lung cancer less than 2 cm in diameter . world j surg . 1998 mar . 22 ( 3 ) : 290 - 4 ; discussion 294 - 5 . [ medline ] .
wu yl , huang zf , wang sy , yang xn , ou w . a randomized trial of systematic nodal dissection in resectable non - small cell lung cancer . lung cancer . 2002 apr . 36 ( 1 ) : 1 - 6 . [ medline ] .
wright g , manser rl , byrnes g , hart d , campbell da . surgery for non - small cell lung cancer : systematic review and meta - analysis of randomised controlled trials . thorax . 2006 jul . 61 ( 7 ) : 597 - 603 . [ medline ] .
manser r , wright g , hart d , byrnes g , campbell da . surgery for early stage non - small cell lung cancer . cochrane database syst rev . 2005 jan 25 . cd004699 . [ medline ] .
naruke t . mediastinal lymph node dissection . general thoracic surgery . 6th ed . philadelphia : lippincott williams & wilkins ; 2005 .
martini n . mediastinal lymph node dissection for lung cancer . the memorial experience . chest surg clin n am . 1995 may . 5 ( 2 ) : 189 - 203 . [ medline ] .
watanabe y , shimizu j , tsubota m , iwa t . mediastinal spread of metastatic lymph nodes in bronchogenic carcinoma . mediastinal nodal metastases in lung cancer . chest . 1990 may . 97 ( 5 ) : 1059 - 65 . [ medline ] .
whitson ba , groth ss , duval sj , swanson sj , maddaus ma . surgery for early - stage non - small cell lung cancer : a systematic review of the video - assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy . ann thorac surg . 2008 dec . 86 ( 6 ) : 2008 - 16 ; discussion 2016 - 8 . [ medline ] .
yan td , black d , bannon pg , mccaughan bc . systematic review and meta - analysis of randomized and nonrandomized trials on safety and efficacy of video - assisted thoracic surgery lobectomy for early - stage non - small - cell lung cancer . j clin oncol . 2009 may 20 . 27 ( 15 ) : 2553 - 62 . [ medline ] .
cerfolio rj , bryant as , eloubeidi ma . accessing the aortopulmonary window ( # 5 ) and the paraaortic ( # 6 ) lymph nodes in patients with non - small cell lung cancer . ann thorac surg . 2007 sep . 84 ( 3 ) : 940 - 5 . [ medline ] .
video - mediastinoscope ( wolf company , knittlingen , germany ) , with the 2 blades opened for demonstration .
r james koness , md , facs program director , fellowship in surgical oncology , roger williams medical center ; clinical assistant professor , division of surgical oncology , department of surgery , the warren alpert medical school of brown university r james koness , md , facs is a member of the following medical societies : american college of surgeons , american head and neck society , society of surgical oncology , american society of breast surgeons disclosure : nothing to disclose .
erik d schraga , md staff physician , department of emergency medicine , mills - peninsula emergency medical associates disclosure : nothing to disclose .
all material on this website is protected by copyright , copyright © 1994 - 2018 by webmd llc . this website also contains material copyrighted by 3rd parties .
urol clin north am . 2001 aug ; 28 ( 3 ) : 491 - 8 .
scott department of urology , baylor college of medicine , houston , texas , usa .
accurate mediastinal staging is the hallmark of a good thoracic oncology program . despite advancements in imaging , surgical staging remains the gold standard of mediastinal staging for lung cancer . this review article summarizes the technique of transcervical mediastinal lymph node dissection and its role in the staging of non - small cell lung cancer ( nsclc ) .
a transverse collar incision is made about 1 cm superior to the sternal notch to a length of 6–8 cm . bilateral anterior jugular veins are divided and subplatysmal flaps are developed superiorly and inferiorly with the upper flap reaching the level of the thyroid cartilage and the lower flap extending below the margin of the sternal notch ( fig .
operative photograph showing the transverse cervical incision to accomplish temla . subplatysmal flaps have been raised and the strap muscles are being separated
in this operative photograph , the rultract retractor hook has been placed retrosternally and the sternum has been elevated . the innominate has been dissected and the right paratracheal space accessed
) . this extensive dissection also facilitates thoracoscopic lobectomy / pneumonectomy as well as saves time by avoiding the need to dissect these stations by vats .
dissection of the deep right paratracheal space . after the lymph node packet is removed , the distal trachea and azygous vein can be clearly visualized
) . occasionally , patients have thoracic inlets mobile and open enough to permit direct viewing of the distal tracheobronchial dissection .
in summary , temla is a promising technique that deserves multi - institutional evaluations for enhanced staging and in approaching the mediastinum for other pathology . future studies are needed to determine whether temla improves patient selection or survival with regards to lung cancer resection .
j thorac oncol : off publication of the international association for the study of lung cancer .
eur j cardiothorac surg : official journal of the european association for cardio - thoracic surgery .
) has remained the popular choice . the purpose of this presentation is to report our experience gained from performing 152 retro - peritoneal lymphadenectomies over the past 18 years and is an attempt at the present time to answer caldwell’s (
these keywords were added by machine and not by the authors . this process is experimental and the keywords may be updated as the learning algorithm improves .
boden , g . , gibb , r . : radiotherapy and testicular neoplasms . lancet ( 1951 )
dean , a . l . : treatment of testis tumors . j . urol . ( baltimore )
dees , j . e . : metastatic embryonal cell carcinoma of testis : an apparent 8 - year cure . j . urol . ( baltimore )


quintiq is a dutch company that develops planning , scheduling and supply chain optimization software .

the company is headquartered in 's - hertogenbosch and its north american headquarters are in radnor , pennsylvania .

quintiq

quintiq radnor , pa isn ' t hiring right now . check out all quintiq jobs
glassdoor has 227 quintiq reviews submitted anonymously by quintiq employees . read employee reviews and ratings on glassdoor to decide if quintiq is right for you .
this is an overview of the quintiq radnor campus or office location . this office is the major quintiq philadelphia , pa area location . find the quintiq radnor address . browse jobs and read about the quintiq radnor location with content posted anonymously by quintiq employees in radnor , pa .
sorry . there are no quintiq customers who meet your search criteria and have chosen to be featured on this site . contact quintiq to discuss quintiq customers in your industry .
quintiq is a software company specializing in advanced planning and scheduling software . quintiq develops and implements advanced planning and scheduling software ; the quintiq software is currently in use in 74 countries .
§ customers of quintiq should realize the new portfolio capabilities of the combined organization .
glassdoor gives you an inside look at what it ' s like to work at quintiq , including salaries , reviews , office photos , and more . this is the quintiq company profile . all content is posted anonymously by employees working at quintiq .
quintiq quickly outgrew its klcc offices - you can now find quintiq in the crown and horizon penthouses of the 1 first avenue building , bandar utama , petaling jaya .
in the short term , ds will move quintiq to its delmia business group where it will remain a separate entity . ds looks set to take on all quintiq ' s employees . quintiq is known as an innovative vendor and we believe this will continue .
as a platinum quintiq implementation partner , we offer complete project management , consultancy and development expertise in implementing quintiq’s supply chain planning and optimization software ( scp & o ) solutions .
quintiq develops its supply chain planning & optimization platform , creates industry - specific software solutions , and maps the strategic and tactical path that quintiq will follow in the coming years .
quintiq arrived in the us in 2005 . quintiq ' s first office was located in wayne , pa , just outside philadelphia . after a successful foray into the us market and subsequent expansion , quintiq relocated its us headquarters to radnor , pa , in november 2010 .
quintiq is now the world’s fourth - biggest supply - chain planning and optimization software company .
ashurst has advised dassault systèmes s . a . ( dassault systèmes ) in the €250m ( approximately a $ 350m ) acquisition of quintiq holding b . v . ( quintiq ) .
quintiq maintains a deep industry domain expertise and has strong professional services . customers like how quintiq approaches the proof of concept step and their responsiveness to customer feedback on areas to enhance and evolve .
at the heart of every quintiq solution are four key ingredients that gives a company the speed , flexibility , and foresight it needs to achieve breakthrough results . presented at the quintiq world tour in singapore .
quintiq was founded in the netherlands in 1997 . the first office was opened in 1999 at the van grobbendoncklaan in ' s - hertogenbosch . quintiq is now located on the utopialaan , ' s - hertogenbosch .
the quintiq software architecture provides companies with a flexible configuration that addresses industry specific processes and customer unique needs .
outside the process manufacturing industry , quintiq has limited value . quintiq will need to expand their functionality and build process templates for discrete or mixed mode industries to compete as a full featured supply chain planning software solution .
to find a quintiq office , click on the map markers or select from the drop - down menu .
quintiq addresses logistic planning integration with their other planning solutions ; but without the operational management functionality . in other words , most companies could not meet all their logistics needs with quintiq ; a wms and tms solution from another vendor is needed to address the non - planning operational activities . quintiq logistic planning software features address the following :
strategic production planning – quintiq solutions use their macro planner for medium - term to long - term production plans .
tactical production planning – the quintiq company planner addresses real - time interactions between sales , planning and production solutions .
official twitter account for quintiq , a dassault systèmes company . global leader in # supplychain planning & optimization software .
alunorf , the world ' s largest aluminum rolling and remelt plant , increased output by 40 % with quintiq .
quintiq has grown rapidly over the years expanding its customers portfolio . year after year quintiq acquires new clients in new industries and as a truly optimization company we constantly work on advancing and optimizing our core software to make our clients happy !
quintiq has been profitable every year since 1997 , and is now known as an industry leader in supply chain planning & optimization . today , approximately 12 , 000 users in numerous global organizations in over 80 countries use quintiq on a daily basis .
quintiq solves every planning puzzle and optimizes every operation for better performance and higher profitability . on a single powerful software platform .
ds will find it challenging to expand quintiq ' s ability to adapt the solution to customer requirements . quintiq is capable in this area , but ds will need to mature and improve . quintiq exploited its ability to customize the solution throughout the customer engagement life cycle , starting in the sales process , where it would invest days building configured workflows to demonstrate its capabilities .
quintiq production planning and scheduling software focuses on avoiding common problems such as high inventory levels , poor customer delivery times , low yield , high scrap and inefficient usage of capacity and production capabilities . quintiq planning and scheduling is addressed over three time horizons :
opened in january 2012 , quintiq ' s office in perth was established to address western australia ' s natural resources market growth . quintiq has dedicated resources and local talent to provide the best level of support possible for its client base in the west .
quintiq does not provide a full warehouse management system . for warehouse management solutions , customers will need to use separate wms software .
trouble with ensuring meat freshness for your end customers ? don’t let disassembly challenges eat you up . get the quintiq expert opinion :
quintiq helps you plan and optimize your operations against your most important business kpis . watch the video to learn more . show less
quintiq llc . delivers supply chain planning & optimization software solutions to a diverse portfolio of clients in the us , canada and mexico in the areas of logistics , workforce , manufacturing and metals . the philadelphia office is home to quintiq ' s ceo and cfo .
quintiq is an international company with a vision to solve every planning puzzle with a single software platform . since its founding in 1997 , quintiq has grown to industry leadership in supply chain planning and optimization . today , our software is in use by fortune . . .
i applied through a recruiter . the process took 2 weeks . i interviewed at quintiq ( radnor , pa ) in march 2013 .
airports are a key market for quintiq as it explores further growth . they are , of course , very dynamic environments , and the inherent flexibility of the quintiq platform in responding to operational changes or disruption in real - time , makes it a vital technology for airports .
quintiq solutions are tightly integrated from high level financial based plans down to detailed factory production scheduling , and provides strong atp and ctp capabilities .
quintiq engineers built the platform to fit any conceivable business model . that’s why we’re able to offer a 100 % fit to every customer .
quintiq ' s first australian office was established in melbourne in january 2008 . since then , the quintiq team has grown rapidly with the acquisition and support of major clients in a broad range of industries including field services , mining , logistics , utilities , public transportation and air traffic control . to accommodate its growing team , quintiq pty ltd moved to a bigger office in st . kilda road in february , 2014 .
quintiq is a leading provider of supply chain and operations planning and optimisation software and dassault systèmes is a leading provider in 3d design software .
quintiq will expand dassault systèmes’ delmia brand , adding the new product line of operations planning and optimization to the existing ones of digital manufacturing and manufacturing operations management . quintiq provides new reach into industries such as metals , mining , oil & gas , rail , delivery and freight .
quintiq opened its first asian offices in 2006 in petronas twin towers in kuala lumpur , malaysia , with an initial team of 5 developers . in just 5 years , the global development center has grown to become quintiq ' s largest department and its sole development center in the world . most of quintiq ' s development activities take place here ; over 240 developers work on customization projects and industry solutions for the business worldwide .
ds is likely to offer a combination of modeling and simulation , and quintiq planning , scheduling and optimization , to joint customers in industries such as mining . we expect the companies will then develop solutions in other industries . but ds must ensure that quintiq ' s resources aren ' t stretched so far in focusing on areas of alignment that it threatens quintiq ' s ability to remain a force in logistics planning and scheduling .
quintiq’s killer app was simple : its algorithms allowed the software to move beyond the limitations of a basic enterprise resource planning system to something different . where existing software simply allowed businesses to systematize their business data — inputting orders and invoices and authorizing payments — quintiq took the next step .
§ dassault systèmes is gaining access to 200 new customers through quintiq , with few overlaps . however , dassault’s traditional strength lies in discrete industries , whereas quintiq is more process focused . this requires a global account strategy to precisely identify the areas where short - term growth opportunities exist .
the quintiq logistic planning solution addresses many of the tms best practice features ; however , it is missing procurement , freight audit and settlement features .
i applied through a recruiter . the process took 5 days . i interviewed at quintiq ( kuala lumpur ( malaysia ) ) in january 2014 .
quintiq ' s supply chain planning and optimization ( scp & o ) solution is designed to help businesses manage their planning and job scheduling activities .
quintiq will expand dassault systèmes ' delmia brand , adding the new product line of operations planning and optimization to the existing ones of digital manufacturing and manufacturing operations management . quintiq provides a new reach into industries such as metals , mining , oil & gas , rail , delivery and freight .
sydney trains to use quintiq ' s solutions to provide computerized decision support for monitoring services and responding to service disruptions at its new rail operations centre .
the transaction involved the acquisition by dassault systèmes of the entire issued share capital of , and cancellation of options to acquire ordinary shares in , quintiq .
quintiq is a leading supplier of advanced supply chain planning and scheduling software solutions for complex process industries covering food , forest , metals and textile products . the quintiq advanced planning and scheduling system aids companies in the planning and utilization of employees , resources and processes , with sophisticated business rules and operational constraints .
dr . victor allis is the ultimate problem solver , and as ceo and founding partner of supply - chain optimization business quintiq , it’s an essential quality .
allis says the focus since the beginning of the quintiq story has been on honing and refining the software packages to a point of certitude . and with the meticulous analysis and careful planning synonymous with allis , quintiq has retained its founding spirit of problem solving , in part thanks to its relatively flat management structure .
every business has its planning puzzles , some large , some complex , some seemingly impossible to solve . quintiq’s vision is to solve every one using a single platform . that vision has driven the development of quintiq software since the first line was coded back in 1997 . our vision is transforming the world’s supply chains .
the quintiq story is one of rapid , successful growth . beginning in 1997 with a group of five ambitious computer programmers , the company now boasts more than 800 employees in offices around the world . coo arjen heeres joined shortly after quintiq was founded , and his own passion for solving planning puzzles echoes the company’s vision .
the logic factory is proud to be a certified quintiq platinum partner . we specialize in the development of advanced software solutions for customers across a broad range of industries , from logistics , maritime and aviation to metals and manufacturing . we are capable of fully executing quintiq implementation projects , from planning and optimization to support and maintenance .
quintiq also works with airlines and air navigation service providers ( ansps ) . indeed , it was recently announced that klm royal dutch airlines has rolled out its software platform to optimise its workforce planning strategies for pilot management . meanwhile , quintiq works with some of the world’s biggest ansps , including deutsche flugsicherung , the faa , and nav canada . quintiq’s workforce planning and optimisation solution enables ansps to create plans that fully incorporate government legislation , labour agreements , and the latest fatigue risk management principles .
the demand management and forecasting software does not have the robust features of the top supply chain management software vendors and many quintiq customers use other products for demand management .
§ quintiq and dassault systèmes began their initial collaboration when working with a customer in the mining industry , which ultimately lead to the acquisition discussions between the two companies .
using process templates , macro planning , company planning and scheduling modules , and optimization algorithms , quintiq is able to support best practices for the more complex process industry challenges .
the acquisition of quintiq , headquartered in ’s - hertogenbosch , the netherlands , extends dassault systèmes’ 3d experience platform to business operations planning and further enables its longtime goal of harmonizing product , nature and life . quintiq will expand dassault systèmes’ delmia brand , adding the new product line of operations planning and optimization to the existing ones of digital manufacturing and manufacturing operations management . quintiq provides a new reach into industries such as metals , mining , oil & gas , rail , delivery and freight . read the press release .
quintiq ' s rome office was initially established in 2010 to meet the growing italian demand for supply chain planning & optimization solutions . it now functions in an operative capacity .
quintiq opened its first french office in the heart of paris in 2013 , and has since invested millions of euros to strengthen its presence in france and to grow the team .
london underground selects quintiq to support long - and medium - term planning as well as day - to - day operations to improve employee satisfaction , process sustainability and customer satisfaction .
“the quintiq solution offers us flexibility when planning for short - term scenarios and also the ability to plan years ahead , enabling us to provide better service to our customers . ”
§ conversely , dassault systèmes should look at cross - selling plant simulation solutions into quintiq captive customer base like steel , glass making , rail , mill production , and energy .
the company has been profitable every year since 1997 . in 2011 private equity firms llr partners inc . and newspring capital ventures lp made an investment in quintiq for a 48 percent ownership position . the original founders and employees still hold a majority of the company . quintiq grew 40 % in 2010 and is expected to have a similar growth rate in 2011 .
over the last few years , quintiq has developed a global footprint and has received funding to continue their business expansion . software delivery or deployment options include on premises and saas solutions .
the team also has access to industry experts from quintiq offices worldwide , which enable the deployment of on - scope , on - budget and on - time solutions to its customers .
another area which the market should consider is how the two companies will manage their direct sales and channel sales . quintiq has predominantly gone direct to the market . delmia has relied on channel sales for its digital manufacturing products and apriso is more of a direct sales and partner approach . quintiq has ramped up its partner efforts recently and it appears to be gaining traction .
demand planning is weak and lacks detailed features . customers may be better off using another demand planning and s & op ; solution , and import the results into quintiq for production planning .
dassault systèmes aims to provide value by connecting all business processes from product design and planning to execution for supply chains . supply chain leaders must ensure dassault will expand quintiq services and support .
marjolijn joined the logic factory in early 2018 and brings over 22 years of project management and consultancy experience . she excels in the implementation of complex software solutions , particularly in the fields of erp , supply chain planning and optimization . prior to joining the logic factory team , she worked with our partner quintiq for 10 years , where she was lastly responsible for quintiq’s european operations .
many of the quintiq software deployments are limited to a supporting role for another supply chain planning software solution . for example , production planning and scheduling solutions become sub components for another scp solution .
eric holds a master’s degree in econometrics from tilburg university . he specializes in designing solutions for logistic operations and complex planning problems , recognizing critical issues at manufacturing sites . besides leading the company , eric continues to be an integral , hands - on leader in all tlf projects . he is level 5 certified and globally recognized as a top quintiq consultant in all key quintiq project roles .
at the 2015 pact enterprise awards , llr partners and newspring capital were honored with the investment deal of the year award for the sale of radnor , pa - based quintiq to dassault systèmes .
global carrier dhl uses quintiq supply chain planning software to schedule and manage its dispatch and delivery processes , managing the daily delivery and pick - up of thousands of parcels in more than 50 countries .
kris kosmala , general manager of quintiq asia pacific , tells a great story of how a container port successfully went beyond their traditional function and is now gaining more profits than ever befo . . .
llr and newspring first invested in quintiq , a provider of on - premise and on - cloud supply chain and operations planning & optimization software , in 2011 . quintiq was acquired by dassault systèmes ( euronext paris : dsy . pa ) , a world leader in 3d design software , 3d digital mock up and product lifecycle management ( plm ) solutions , in october 2014 for approximately €250 million .
read more about the origins of llr’s investment in quintiq , the company’s growth and sale to dassault in this acg philadelphia profile and click here for the complete list of 2015 pact enterprise award winners .
since then quintiq has grown from a group of five programmers in a small office in ' s - hertogenbosch , the netherlands , to a company with close to 1000 employees in offices around the world .
dassault said it would pay about 250 million euros ( $ 336 million ) in cash for netherlands and united states based , privately - held quintiq , which is majority owned by its senior management team .
secure assurances about the availability of key quintiq personnel , particularly in logistics . check any new terms and conditions ( t & cs ) , as ds ' s t & cs are tougher than some .
kind of interdependency , ” heeres commented . “the platform we provide is one where you can capture all those puzzles , identify where they all work in collaboration with each other , and find the best possible solution given the circumstances . ” quintiq has recently been acquired by dassault systems , which will only strengthen its focus on the aviation business . airports are a key market for quintiq as it explores further growth . they are , of course , very dynamic environments , and the inherent flexibility of the quintiq platform in responding to operational changes or disruption in real - time , makes it a vital technology for airports .
kevin gaskell , former managing director at porsche gb and bmw , talks to quintiq about bringing the best out of people and how porsche jumped to number one from 31 in customer satisfaction . breakth . . .
charlie macdonald , cio of db schenker australia , talks to quintiq about the role of the internet of things and how connecting an instrument in your supply chain can lead to better visibility and se . . .
for further information : for further information : quintiq , martijn van gils , marketing director , tel . + 31 ( 0 ) 73 - 6910739 , e - mail : martijn . van . gils @ urltoken
evaluate the solutions on their individual merits . don ' t factor in any potential value from a converged offering until such a solution exists . prospects of quintiq ' s logistics offerings should conduct extensive due diligence .
quintiq does not provide a procurement module ; supply planning and optimization is addressed in their company planner module . for full feature procurement solutions , customers will need to use their erp software or another supply chain solution .
“what if you could anticipate the number of passengers at check - in ? you could then plan your staff and counters accordingly . ” – conny van der heijden , quintiq ground operations business consultant . learn more :
our vision is to transform the world’s supply chains . with more than 700 employees in 16 offices around the world , quintiq is ready and able to help any company with their planning puzzles , no . . .
ds and quintiq focus on different industries with only some overlap in manufacturing and workforce management . this gives ds growth opportunities . the few areas of industry overlap give some medium - term opportunities for both product lines .
such has been the success of quintiq’s offering that growth has been nothing short of phenomenal . within 10 years of being established in the netherlands , the business was reporting an average annual growth rate of approximately 40 % .
copenhagen airports , operator of the busiest hub in the nordic region , is using quintiq’s software platform to plan its workforce . copenhagen airport handled a record 24 . 1 million passengers last year , and quintiq has provided a single integrated software platform to optimise the planning of the airport’s workforce of 2 , 100 staff . its software implementation also includes the deployment of a mobile application , integration with sap payroll , and the automation of key planning tasks .
dr . mahender singh , the founding ceo of the malaysia institute for supply chain innovation , talks to quintiq about why it ' s worth investing in asia and why it ' s difficult for a solutions provider t . . .
quintiq goes to great lengths to make their employees happy and productive . since the acquisition by dassault systemes , the original quintiq leadership fought tooth and nail to keep the best benefits we have , because that is part of what makes us love working here . the work is challenging and interesting . we get to work with any number of different industries , and different people from around the world . the customers vary widely and often make the job more fun .
utilizing their sophisticated planning and optimization modules , quintiq provides customers with an array of solutions to manage and optimize the balance between customer needs , inventory levels and operating costs . the following solutions help customers address distribution , replenishment and fulfillment :
in 2008 , quintiq also established its regional head office for southeast asia and india here in malaysia , to address the growing market opportunities throughout the region as well as to support the company ' s rapidly developing southeast asian customer base .
that’s what we do . ” having fun playing around with possible scenarios and their solutions has been central to quintiq’s success , with allis as innovator - in - chief . and this unique application of puzzle solving seems to be proving extremely popular .
business units around the world manage their own profit and loss , while managers have the freedom to choose which customers they pursue and who they hire . the autonomy quintiq allows its managers stems from allis’ insistence on treating them like grown - ups .
klm royal dutch airlines uses quintiq supply chain planning software to schedule the transitions , vacations and training of more than 2 , 000 commercial pilots while klm catering services leverages the daily distribution of 40 , 000 meals to aircraft at the amsterdam airport .
in 1997 five computer programmers began work on a new scheduling application for one of the world’s largest aluminum hot mill operators . their mission was to develop planning & optimization software that could be configured to suit any business model . the unique and sophisticated algorithms they created were pivotal to quintiq’s success , as were the vision and direction provided by former ceo victor allis ( who was also one of those five programmers ) and former coo arjen heeres ( who joined shortly after quintiq was founded ) .
for more information please send an e - mail to mg @ urltoken . for consideration , please upload your resume and a cover letter stating why you are applying for this position . for more information on quintiq please visit their website at urltoken .
quintiq brings record - breaking decision support and optimization technology to the most complex global business planning challenges . now , in combination with dassault systèmes’ leadership in the experience economy , we will bring our customers new levels of innovation , operational efficiency and performance .
§ dassault systèmes is set to develop a data management platform , which will further help quintiq customers to capture and enforce clean and reliable data to create supply and demand plans , and enhance the capabilities to manage the entire logistics of the its operations .
unfortunately , a corporate takeover by dassault systemes promises to remove the quintiq culture . work - life balance depends on your project . long days , late nights , travel , and even weekend work can be necessary and sometimes common . additional work both within and beyond your own project is expected , to assist others . in return , quintiq compensated with time - for - time ( paid overtime or extra time off ) . but , time - for - time is being taken away . in fact , management has approached employees on this with some aggression , and we ' ll lose earned time - for - time retroactively from the beginning of the year . as opposed to quintiq ' s culture , dassault systemes evidently prefers a standard corporate top - down approach .
paris ( reuters ) - dassault systemes is to buy business planning software company quintiq , its second acquisition this month , taking the french management solutions company into the metals , mining , oil and gas , rail delivery and freight industries for the first time .
on 24 july 2014 , dassault systèmes ( ds ) , a french design and product life cycle management vendor , announced that it plans to acquire quintiq , a dutch planning and optimization vendor with strong supply chain credentials . the deal is due to complete in september 2014 .
initially , that meant inviting several companies to a seminar , where he showcased the product software to give a taste of what it could do . today , quintiq is signing up international retail giants as well as customers from the mining , manufacturing , metal , transport and logistics industries .
quintiq has a very flat structure , which is great because you work among your equals . as you gain experience , you will be given additional responsibilities . but , your official title won ' t change . some people want to move up a structured managerial latter as they put in their time . i would say that quintiq does not follow this structure . sales cycles are battles of attrition , but the rewards are huge . this means that the difference between a good year and a bad year is often whether or not your business unit had a single sale .
while they developed the product , they took on contracting work — consulting on business processes — which earned enough money to pay the interest on the loan until they were ready to go to market . two years down the line , the product was ready and quintiq signed its first contract .
250 million . with 800 employees , quintiq , whose offerings include production , logistics and workforce planning applications , is rated as a leader in the market by top industry analysts and its solutions are used today by 250 customers , at 1 , 000 sites , in more than 90 countries .
you will be involved at every stage of the implementation , from determining the compatibility of quintiq with the customers’ existing solutions during the pre - sales cycle , to troubleshooting following go - live . you will be assigned to a project team . you will report directly to the team manager .
the logic factory offers customers utilizing a quintiq scp & o a flexible , fully integrated range of software maintenance , support and control services . service levels are fully customizable and can include anything from corrective maintenance and incident management to out regular preventive check - ups and pro - active system management .
founded in 1997 , quintiq seeks to solve supply planning puzzles for large and complex companies . its customers include chip tool maker asml , cement group lafarge , and steelmaker arcelormittal . it also plans and optimizes operations for delivery groups dhl and tnt , global retailer walmart and the federal aviation administration .
different puzzles call for different methods . taking only one approach to optimization is never the right approach . get a faster roi and better quality plans when you rely on quintiq’s optimization technology . it combines optimization technologies and techniques in a way that means you’ll always get the optimal solution to your puzzle .
with approximately 350 employees worldwide , $ 45 million in revenues , and scm software products in use at over 500 sites in 77 countries , quintiq is a small privately held software vendor with a short history . nonetheless , the company has an impressive list of customers with marquee brands which include the following :
again the collaborative feature doesn ' t have all the robust functionality of other demand management software solutions . quintiq does have provisions built into the architecture that support it standards to share data with other business systems ; but , this does not address the more robust and sophisticated collaborative features to be considered a best practice .
arjen heeres , quintiq coo : “we can strategically help airports determine at what level they should invest in new infrastructure , for example . we can also assist on a practical level with capacity planning and staff rostering , while on an operational level , we can help minimise the effects of last minute disruptions in real - time . ”
the solution helps to manage production , logistics , or the workforce , spanning from strategic , to tactical , to operational . quintiq ' s supply chain planning & optimization works to support the needs of businesses , no matter the industry , size , or functionality requirements . the planning interface allows departments to collaborate and communicate common goals .
ds ' s vision is a bold one that should be valuable to users . ds is likely to maintain quintiq ' s value . it will probably successfully articulate a strong vision to customers and prospects . but the challenge for ds will be delivering this vision to the market and selling it to organizations at the right level of readiness .
having completed his phd in artificial intelligence , allis was lured by the puzzles of the business world and joined a knowledge technology firm as a senior consultant and manager . but when that business rejected his big idea in 1997 , he joined up with four computer programmers to form quintiq and got to work creating a custom - made scheduling application .
attracting bright minds with phds and master’s degrees , quintiq’s recruitment process is rigorous , with puzzles and practical tests a key part of the process . “we are also looking for a cultural fit , ” says allis , “so we like people who are open but also show humility and want to win for the team and not just for themselves . ”
quintiq offers a variety of features to monitor the management of supply chains , including optimization capabilities . its real - time planning environment includes a propagation engine that calculates and visually displays the consequences of potential or real - time changes and events . this scenario planning can help businesses visualize the effect of certain changes before these changes are put into place .
quintiq brings it all together . it’s one planning system to cover every aspect of planning , from long - term strategic plans to short - term schedules and disruption management . every department and every user can customize the interface and the information visible to suit preferences and requirements . plans are updated in real - time for company - wide transparency and collaboration .
§ dassault systèmes’ acquisition in the core manufacturing operations software space have included intercim ( 2011 ) , apriso ( 2013 ) and now quintiq ( 2014 ) . these acquisitions have enabled dassault systèmes to add at least $ 4 - 6 bn in additional addressable market . this will potentially increase dassault systèmes addressable market to ~ $ 36 - 41 bn market .
the company now employs 700 people and has operations in more than 20 countries . while allis is dutch , he is now based at the company’s us office in pennsylvania and sees his role today as maintaining the original quintiq ethos of approaching each conundrum with a fresh , innovative approach — something he has been careful to instill in his army of engineers and programmers .
quintiq multi - level supply chain optimization software provides planners visibility into all aspects of the supply chain , and enables real - time management and optimization of production capacities , raw materials , and order fulfillment . the product mix optimization solution , using the macro planner , helps to identify the ideal product portfolio to maximize profits . macro planner also addresses optimal safety stock levels and customer service levels .
by using a range of data inputs to spot patterns and use resources more efficiently , quintiq was able to help businesses optimize their supply chain and logistics , and therefore save them time and money . “if you look at the role of business , whether it is about making products , moving things or deploying people , there’s always an enormous puzzle : how do we get everything to flow optimally ? ”
about shaun joughin shaun joughin is a senior logistics consultant at quintiq emea . he is a planning expert in various segments of the logistics industry including postal , maritime , and intermodal transport . but shaun’s passion lies with the maritime sector , where he has been helping companies improve their bottom line through improved planning on both the landside and shipping areas of the transportation market . he holds a degree in mathematics from durham university in the uk .
ds ' s latest acquisition will enable it to expand into the supply chain management market , and supply chain planning in particular . quintiq is a strong vendor in planning , scheduling and optimization — its solution can address most planning problems through its functional depth and configurability , and its talent pool is deep . ds believes that , through planning and execution , it can create value for customers by connecting all business processes from product / service innovation , design and production to final delivery .
quintiq supply chain design lets customers perform strategic long - term scm plans and make informed decisions regarding major activities such as capital investments , portfolio product mix , inventory levels , outsourcing , and customer service strategies . multi - scenario functionality lets customers generate ' what - if ' supply chain configurations that cover production sites , suppliers , inbound and outbound logistics , warehouses , distribution centers and more . the different scenarios can be analyzed to determine their impact on profits , costs , inventory levels and delivery performance .
quintiq s & op ; solution is based on their macro planner module and outputs from demand forecasting . macro planner reaches a balance between demand and supply chain capabilities , and addresses safety stock levels and available to promise . software feature sets address inventory optimization , strategic plans , resource capacity , sourcing , distribution and multiple scenario
what if
contingencies . the dynamic performance analysis module allows planners to monitor results based on key performance indicators ( kpi ) , thus allowing for midcourse corrections in the s & op ; plans .
there are many cross - synergies between dassault systèmes , apriso and quintiq in terms of solution offerings , customer business drivers and industry challenges . the capability to deliver solutions from product conception to planning , optimization and delivery , provides a comprehensive technology platform for customers . very few companies have a semblance of similar solution offerings , and those that do are facing significant integration challenges . realistically , it will likely take at least 2 - 3 years for dassault systèmes to realize the impact of this solution strategy and how it will positively impact the operating margins of the organization .
in the longer term , ds will talk about
business operations planning
in its delmia business group . it will try to use quintiq to drive planning across all types of resources at every level , linking ds product design and manufacturing / logistics execution capability ( from its apriso acquisition ) . converging these areas may create synergy if ds executes well . however , big acquisition strategies are rarely successful . ds has a good track record of keeping acquired talent , but it will probably take years to pull off this ambitious convergence strategy — if it does at all .
quintiq takes a somewhat unique architectural approach that breaks up their supply chain planning software into three layers . the first layer has many of the features of a soa platform , the second layer addresses industry practices with a number of different market templates and the third layer is the customer specific layer . imbedded in the first layer are a planning platform consisting of a demand , macro , company and schedule planning modules , and an optimization platform with math algorithms , analytics , an event propagator , a business modeler , workflow and other functionalities . the underlying architecture powers many of the unique business processes and software capabilities .
“jps selection are the most tenacious , well - mannered and supportive recruitment consultants i have the experience of working with . all too often , recruitment consultancies don’t listen to what their clients want ( and we the candidates , are as much their clients as the prospective company ) . jps selection are one of the few exceptions in this industry . throughout the recruitment process to join quintiq , they coached , listened to my concerns , answered my questions clearly and supported me continuously . at all stages , i knew where the potential interview pitfalls lay and with their guidance , successfully got the job . i have no hesitation recommending jps selection to prospective candidates . ”
second , build a network that goes beyond technical specialists . it doesn’t have to be big , but it has to be diverse . foster relationships with experienced and successful people outside of your field . what you learn from your connections in construction , advertising , finance , and so on will help you to become a well - rounded leader with the broad skillset needed in the c - suite . and give you a much deeper understanding of the world in which your customers and employees operate . even when i was leading quintiq’s r & d , i made sure to spend about half of my time out in the field , to keep myself , my team and the technology grounded in reality .
central to this vision is the ability to solve each planning puzzle using a single supply chain planning and optimisation software platform . “we optimise and plan larger operations with multiple planning puzzles , each of which have some
heeres’ concluding sentiment was that optimisation is typically underestimated , but the benefits are tangible . “you need to be precise in capturing the operation of an airport . that requires quite some work , but my recommendation is look into it and really make the effort to understand why , if you put the effort in , the rewards can be enormous . ”
don ' t miss out on the latest news from aci europe airport business - receive our newsletter straight to your inbox when new content is published .
airport news - including reports on the latest strategic , operational and political viewpoints from all of the world ' s airports , airlines and governmental authorities .
special editions - exclusive access to our special reports which detail how airport operators have approached major expansion projects .
conference updates - receive all the latest news on conference developments from aci europe as well as notifications of early booking discount deadlines .
for inquiries related to this message please contact support . for sales inquiries , please visit urltoken
if you believe this to be in error , please confirm below that you are not a robot by clicking
i ' m not a robot
below .
please make sure your browser supports javascript and cookies and that you are not blocking them from loading . for more information you can review the terms of service and cookie policy .
html public
- / / w3c / / dtd xhtml 1 . 0 transitional / / en
urltoken
data management addresses the basics , but may not have all the bells and whistles that sap , oracle and jda include in their demand management solutions . there are features to accept statistical data from other systems , share forecasts throughout the organization and handle multi - forecast scenarios .
victor allis solved his first rubik’s cube at a very early age . while at school , in between earning a few dutch guilders tutoring older students in mathematics , he represented the netherlands in the international mathematical olympiad and finished 14th in the world .
it was clear the boy had talent . “when i got to university , i started to create programs that played thinking games , programs that played chess , connect four , go and all sorts of weird games , ” he remembers . “
the question is always , how do you outwit your opponents ? so in 1988 , i wrote a program that played connect four perfectly .
i was always intrigued by how you have a puzzle that has an enormous number of possibilities and how you find the optimal path to the solution . for those who subscribe to malcolm gladwell’s outlier theory , which holds that successful people are defined by insatiable hunger for their subject allied with relentless practice , then victor allis is living proof .
he’s one of the very few academics to have translated their natural intellect into business success . today , it is a background that makes him stand out in the business world .
while many leaders would focus on sales and marketing , allis takes a rigorous and scientific approach to perfecting the product , ensuring that it always provides the best possible solution . for allis , this is a prerequisite for success and growth .
keen to keep 100 % control of the business , the founders avoided asking for venture capital in order to fund it . instead , each put a sum into the company , supported by a substantial bank loan .
find out how collaboration between the cfo and supply chain – and all disciplines – is indispensable , in our report , partnering for performance : the cfo and the supply chain .
allis explains : “what we find is that when a business gets to a certain complexity , it needs to change . so we made a single software application that can solve all those puzzles .
operations were expanded beyond europe to the us and then asia , where allis sees exceptional opportunities — not just to grow consumer markets , but also to tap into the extraordinary talent and energy of the emerging graduate class there to provide the next wave of programming geniuses . growth came , allis says , through being able to demonstrate the power of the product .
“i’ve found that , if you start by trusting people , you get a lot of trust back , ” he says . “if you start by distrusting people , they start trying to work around the rules .
so i think control is not an effective baseline to manage a business . it’s an inefficient way , because what you’re trying to do is stop people from doing things they want to do . ”
of course , this places greater pressure on executives to find the right talent . allis , though , is unperturbed . “all i can do is help hire the right people and make an environment where you want to be .
then i can support the right initiatives and maybe slow down some of the wrong ones . ” that working environment is one where there is a no - blame culture and where individuals are encouraged to be confident and experiment .
allis’ meticulous approach has its origins in his academic background , which , it should be said , does not conform to the stereotypical back story of the successful entrepreneur . “i never grew up thinking i wanted to be a businessman or an entrepreneur , ” he admits .
but he says his insatiable desire for the next challenge did free him from the fear of failure that restricts many of those with a good idea but doubts about their ability to carry it off . it’s certainly clear allis has extraordinary drive .
when he’s not solving puzzles , he relaxes by doing endurance running , and in his youth he played in the team that won the dutch basketball championship in 1979 .
the experience taught allis an important lesson : “it left me with a feeling that if you want to achieve something and are able to set your mind on it , there’s no good reason why you shouldn’t try . ” it is a lesson that has served him well in business .
as allis looks out from the window of his 12th - story office in den bosch in the netherlands , he ruminates on where the company can go next . has he completed the puzzle ?
“no , not yet . i think there will probably be more puzzles in more areas . right now , we don’t think we will change course in the next 5 or 10 years . ”
allis is most concerned about maintaining the business’s innovative edge . “i don’t worry too much about the long - term future , but i worry every single day about what we’re missing today that we could do to be better next quarter or next year , ” he says .
it comes back down again to the view that if the product is as perfect as it can be , success in the rest of the business should follow . “some people say you can be either an entrepreneur or a manager . i don’t think that is necessarily true . ”
“entrepreneurs are people who say ‘why not ? i can do that’ and think outside the box . managers are diligent people who hold to their promises and do the things that are needed . ”