Question: query regarding a cow showing the signs of marble like growth on the skin from last two month, the animal was treated with 1 ml  ivermectin injection,& antihistamine  but  it does not show any signs of recovery 
Answer:  1 ml ivermectin ( for 50 kg body weight ) may not be sufficient for the heifer, repeat the dose again after 20-22 days of 1 st injection, several injections may require to minimise the occurrence, insted of  ivermectin one can try withanthiomalein injection with vetcort forte injection, besides auto- haemo therapy can be done with consultation with the local veterinarian ( 3-4 month may require for recovery ), the the blood & tissue can be semnt to the advance animal disease diagnosis centre for conformative diagnosis wheather it is myoma , fibrisarcoma